Produção Nacional
Lenise Jihe Kim, Fernando Morgadinho Santos Coelho, Camila Hirotsu, Paula Araujo, Lia Bittencourt, Sérgio Tufik, Mônica L. Andersen,
... PhD, Camila Hirotsu, PhD, Paula Araujo, PhD, Lia Bittencourt, MD, PhD, Sergio Tufik, MD, PhD, Monica Levy Andersen, PhD Lenise ... Federal de São Paulo, São Paulo, Brazil , Lia Bittencourt, MD, PhD Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brazil , Sergio Tufik, MD, PhD Departamento de Psicobiologia, Universidade Federal ...
Tópico(s): Restless Legs Syndrome Research
2015 - American Academy of Sleep Medicine | Journal of Clinical Sleep Medicine
Produção Nacional
Priscila Farias Tempaku, Camila Hirotsu, Diego R. Mazzotti, Gabriela Xavier, Pawan Kumar Maurya, Elisa Brietzke, Síntia Belangero, Dalva Poyares, Lia Bittencourt, Sérgio Tufik,
... Sintia Belangero, PhD, Dalva Poyares, MD, PhD, Lia Bittencourt, MD, PhD, Sergio Tufik, MD, PhD Priscila Tempaku, MsC Department of ... Search for more papers by this author , Lia Bittencourt, MD, PhD Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil Search for more papers by this author , Sergio Tufik, MD, PhD Address correspondence to: Sergio Tufik, ...
Tópico(s): Sleep and related disorders
2018 - American Academy of Sleep Medicine | Journal of Clinical Sleep Medicine
Produção Nacional
Priscila Farias Tempaku, Diego R. Mazzotti, Camila Hirotsu, Mônica L. Andersen, Gabriela Xavier, Pawan Kumar Maurya, Lucas B. Rizzo, Elisa Brietzke, Síntia Belangero, Lia Bittencourt, Sérgio Tufik,
... 2,4 , Sintia Iole Belangero 2,5 , Lia Bittencourt 1 and Sergio Tufik 1 1 Departamento de Psicobiologia, Universidade Federal ...
Tópico(s): Nutritional Studies and Diet
2016 - Impact Journals LLC | Oncotarget
Produção Nacional
Revisado por pares
Helena Martí-Soler, Camila Hirotsu, Pedro Marques‐Vidal, Péter Vollenweider, Gérard Waeber, Martin Preisig, Mehdi Tafti, Sérgio Tufik, Lia Bittencourt, Sérgio Tufik, José Haba‐Rubio, Raphaël Heinzer,
Background Diagnosis of sleep-disordered breathing requires overnight recordings, such as polygraphy or polysomnography. Considering the cost and low availability of these procedures, preselection of patients at high risk is recommended. We aimed to develop a screening tool allowing identification of individuals at risk of sleep-disordered breathing. Methods We used the participants from the population-based HypnoLaus cohort in Lausanne, Switzerland, who had a clinical assessment and polysomnography ...
Tópico(s): Dysphagia Assessment and Management
2016 - Elsevier BV | The Lancet Respiratory Medicine
Produção Nacional
Revisado por pares
Daniel Ninello Polesel, Karen Tieme Nozoe, Sérgio Tufik, Andréia Gomes Bezerra, Maria Teresa Bechere Fernandes, Lia Bittencourt, Sérgio Tufik, Mônica L. Andersen, Helena Hachul,
This study aims to investigate anthropometric measures and their effectiveness as screening method for diagnosing obstructive sleep apnea (OSA) in each gender. We also evaluated which measures were associated with OSA in the adult population of a large metropolitan city, Sao Paulo, Brazil. 552 women and 450 men were submitted to polysomnography (PSG), and the anthropometric measurements as body mass index (BMI), waist-to-height ratio, neck and waist circumference were collected. The measurements were ...
Tópico(s): Neuroscience of respiration and sleep
2019 - Brazilian Association of Sleep and Latin American Federation of Sleep Societies | Sleep Science
Produção Nacional
Revisado por pares
Joachim A. Behar, Niclas Palmius, Sroussi Zacharie, Armand Chocron, Thomas Penzel, Lia Bittencourt, Sérgio Tufik,
Portable oximetry has been shown to be a promising candidate for large-scale obstructive sleep apnea screening. In polysomnography (PSG), the gold standard OSA diagnosis test, the oxygen desaturation index (ODI) is usually computed from desaturation events occurring during sleep periods only, i.e. overnight desaturations occurring during or overlapping with a wake state are excluded. However, for unattended home oximetry, all desaturations are taken into account since no reference electroencephalogram ...
Tópico(s): Non-Invasive Vital Sign Monitoring
2020 - IOP Publishing | Physiological Measurement
Produção Nacional
Revisado por pares
Francieli S. Ruiz, Daniela Santoro Rosa, Ioná Zalcman Zimberg, Marcus Vinicius Lúcio dos Santos Quaresma, Jethe O.F. Nunes, Juliana de Souza Apostólico, Lily Yin Weckx, Alessandra R. Souza, Fernanda Veruska Narciso, Silvio A. Fernandes‐Junior, Bruno da Silva Brandão Gonçalves, Simon Folkard, Lia Bittencourt, Sérgio Tufik, Marco Túlio de Mello,
It is well-established that sleep regulates immune functions. Immunological functions are dependent on circadian rhythms and regular sleep as both have an impact on the magnitude of immune responses following antigenic challenge (eg, in vaccination). Here we investigated whether nocturnal shift work can influence post-vaccination response. Thirty-four healthy workers (23 females) working either nocturnal or diurnal shifts (17 in each group) received the meningococcal C meningitis vaccine. Sleep was ...
Tópico(s): Sleep and related disorders
2020 - Elsevier BV | Sleep Medicine
Produção Nacional
Revisado por pares
Fernando Gasi, Gilberto Petraconi Filho, Edison Bittencourt, Sérgio Ricardo Lourenço, Alonso Hernan Ricci Castro, Felipe Miranda, Alexei Mikhailovich Essiptchouk, Larissa Nascimento, André Petraconi, Mariana Amorim Fraga, Rodrigo Sávio Pessoa,
In this study, the hybrid corona-dielectric barrier discharge plasma treatment was employed to modify the physical, chemical and morphological characteristics of a half-knitted fabric composed of 92% polyamide 6.6 and 8% elastane (PA). These properties of the fabric were evaluated by the water contact angle, x-ray diffraction, infrared spectroscopy, scanning electron microscopy and atomic force microscopy techniques. In addition, the dyeing and washing processes were also investigated. A significant ...
Tópico(s): Electrospun Nanofibers in Biomedical Applications
2019 - Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímer | Materials Research
Produção Nacional
Revisado por pares
Joachim A. Behar, Niclas Palmius, Qiao Li, S. Garbuio, Fabíola Paula Galhardo Rizzatti, Lia Bittencourt, Sérgio Tufik, Gari D. Clifford,
The growing awareness for the high prevalence of obstructive sleep apnea (OSA) coupled with the dramatic proportion of undiagnosed individuals motivates the elaboration of a simple but accurate screening test. This study assesses, for the first time, the performance of oximetry combined with demographic information as a screening tool for identifying OSA in a representative (i.e. non-referred) population sample.A polysomnography (PSG) clinical database of 887 individuals from a representative population ...
Tópico(s): Cardiovascular and Diving-Related Complications
2019 - Elsevier BV | EClinicalMedicine
Produção Nacional
Revisado por pares
Camila Hirotsu, José Haba‐Rubio, Sônia Maria Togeiro, Pedro Marques‐Vidal, Luciano F. Drager, Péter Vollenweider, Gérard Waeber, Lia Bittencourt, Sérgio Tufik, Raphaël Heinzer,
Cross-sectional studies have demonstrated that obstructive sleep apnoea (OSA) and metabolic syndrome (MetS) are often associated, but whether a temporal relationship exists is unknown. We aimed to investigate the effect of OSA on the risk of developing MetS in the general population. A prospective study was conducted combining two population-based samples: Episono (Brazil) and HypnoLaus (Switzerland). MetS was assessed according to unified criteria. Polysomnography (PSG) was performed at baseline and ...
Tópico(s): Cardiovascular and Diving-Related Complications
2018 - European Respiratory Society | European Respiratory Journal
Produção Nacional
Revisado por pares
Marcos Mônico‐Neto, Hanna Karen Moreira Antunes, Ronaldo Vagner Thomatieli dos Santos, Vânia D’Almeida, Altay Alves Lino de Souza, Lia Bittencourt, Sérgio Tufik,
Obstructive sleep apnoea (OSA) is positively associated with cardiometabolic diseases; however, high levels of physical activity could decrease the incidence of OSA and associated comorbidities. In this study we aimed to examine the incidence of OSA in relation to physical activity, and its role as a protective factor in individuals with OSA on the incidence of cardiometabolic diseases, in an 8–9-year follow-up study. We analysed data of 658 volunteers from the São Paulo Epidemiologic Sleep Study ( ...
Tópico(s): Sleep and related disorders
2018 - European Respiratory Society | European Respiratory Journal
Produção Nacional
Revisado por pares
Zaira Fernanda Martinho Nicolau, Andréia Gomes Bezerra, Daniel Ninello Polesel, Mônica L. Andersen, Lia Bittencourt, Sérgio Tufik, Helena Hachul,
The aim of this study is to compare sleep characteristics between women with premenstrual syndrome (PMS) and a control group. The data were extracted from an epidemiologic survey conducted in Sao Paulo (EPISONO), Brazil, which used subjective assessments and objective polysomnography records to analyze subjects' sleep pattern. Subjective questionnaires used in this study were Women's Questionnaire, Pittsburgh Sleep Quality Index, Epworth sleepiness scale, Insomnia Severity Index and the general sleep ...
Tópico(s): Biochemical effects in animals
2018 - Elsevier BV | Psychiatry Research
Produção Nacional
Andressa Silva, Marco Túlio de Mello, Paula Regina Mendes da Silva Serrão, Roberta Pitta Costa Luz, Francieli S. Ruiz, Lia Bittencourt, Sérgio Tufik, Stela Márcia Mattiello,
It has been demonstrated in recent studies that obstructive sleep apnea (OSA) is the most prevalent sleep disorder in patients with osteoarthritis (OA), and thus the current study aimed to investigate the influence of OSA on knee extensor torque, pain, stiffness, and physical function in men with low-grade knee OA.The study included 60 male volunteers, aged 40 to 70 years, allocated into four groups: Group 1 (G1) Control (n = 15): without OA and without OSA; Group 2 (G2) (n = 15): with OA and without OSA; ...
Tópico(s): Obstructive Sleep Apnea Research
2018 - American Academy of Sleep Medicine | Journal of Clinical Sleep Medicine
Produção Nacional
Revisado por pares
Márcio H. Miname, Márcio Sommer Bittencourt, Sergio Moraes, Rômulo I.M. Alves, Pãmela R.S. Silva, Cinthia E. Jannes, Alexandre C. Pereira, José Eduardo Krieger, Khurram Nasir, Raúl D. Santos,
The aim of this study was to evaluate the role of coronary artery calcium (CAC) as a predictor of atherosclerotic cardiovascular disease (ASCVD) (fatal or not myocardial infarction, stroke, unstable angina requiring revascularization, and elective myocardial revascularization) events in asymptomatic primary prevention molecularly proven heterozygous familial hypercholesterolemia (FH) subjects receiving standard lipid-lowering therapy. FH is associated with premature ASCVD. However, the clinical course ...
Tópico(s): Coronary Interventions and Diagnostics
2018 - Elsevier BV | JACC. Cardiovascular imaging
Produção Nacional
Revisado por pares
Tim J. Gabbett, Rasmus Oestergaard Nielsen, Michael Lejbach Bertelsen, Natália Franco Netto Bittencourt, Sérgio T. Fonseca, Shane Malone, Merete Møller, Eric Oetter, Evert Verhagen, Johann Windt,
The goal for sports medicine practitioners is to develop robust athletes, capable of withstanding high training and competition loads. For sports medicine professionals, understanding the workload–capacity relationship is central to achieving this goal. This editorial discusses how two different methodological frameworks—(1) moderation and (2) circular causation—align to develop physical capacity and injury resilience in athletes. The Arab proverb ‘ the straw that broke the camel’s back’ refers to ...
Tópico(s): Sports injuries and prevention
2018 - BMJ | British Journal of Sports Medicine
Produção Nacional
Revisado por pares
José Tadeu Tesseroli de Siqueira, Cinara Maria Camparis, Sílvia Regina Dowgan Tesseroli de Siqueira, Manoel Jacobsen Teixeira, Lia Bittencourt, Sérgio Tufik,
The purpose of this study was to investigate whether the presence of concomitant widespread pain could influence the polysomnographic characteristics of patients with Sleep Bruxism(SB) and chronic masticatory muscle pain(TMD). 20 SB/TMD patients (17 women and 3 men) were evaluated according to the RDC/TMD questionnaire; and were divided into two groups according to the absence (Group A) or presence (Group B) of widespread pain. They were evaluated in a one night polysomnography paradigm. Group B had ...
Tópico(s): Restless Legs Syndrome Research
2017 - Elsevier BV | Archives of Oral Biology
Produção Nacional
Revisado por pares
J H Soterio-Pires, Camila Hirotsu, Lenise Jihe Kim, Lia Bittencourt, Sérgio Tufik, Mônica L. Andersen,
Tópico(s): Eating Disorders and Behaviors
2016 - Springer Nature | International Journal of Impotence Research
Produção Nacional
Revisado por pares
Camila Hirotsu, Rachel G. Albuquerque, Heloisa Nogueira, Helena Hachul, Lia Bittencourt, Sérgio Tufik, Mônica L. Andersen,
Obstructive sleep apnea (OSA) has been associated with increased risk of cardiovascular morbidity and mortality. Although inflammatory markers may mediate this association, it is unknown the influence of gender in this mechanism. Thus, we aimed to evaluate the interaction effects between OSA and gender on metabolic and inflammatory profile in a population sample. This study is part of EPISONO cohort, in which 1042 participants underwent polysomnography, answered questionnaires, and had their blood ...
Tópico(s): Sleep and Wakefulness Research
2016 - Elsevier BV | Brain Behavior and Immunity
Helena Hachul, Daniel Ninello Polesel, Nozoe KT, Sanchez Zm, Prado MCO, Andersen Ml, Lia Bittencourt, Sérgio Tufik,
Purpose: To characterize the onset of natural menopause and to investigate the associated factors with the age of menarche and natural menopause in a population aged 29-59 yrs in Sao Paulo, Brazil. Methods: In total, 426 women underwent clinical evaluation and blood collection for biochemical analysis. Participants were classified as being in the premenopausal or natural menopausal stage. Results: The results showed that the mean age of menarche was 12.7 yrs and that the mean age of menopause was ...
Tópico(s): Estrogen and related hormone effects
2016 - OMICS Publishing Group | Journal of Women s Health Care
Produção Nacional
Revisado por pares
Daniel Ninello Polesel, Camila Hirotsu, Karen Tieme Nozoe, André Campiolo Boin, Lia Bittencourt, Sérgio Tufik, Mônica L. Andersen, Helena Hachul,
Objective The current study aimed to investigate stages of reproductive aging as an associated factor for obstructive sleep apnea syndrome (OSAS) among women in a representative sample of Sao Paulo, Brazil. Methods Four hundred seven women underwent clinical evaluation, polysomnography, and biochemical analysis. Stages of reproductive aging were defined as premenopause, early postmenopause, and late postmenopause. Results OSAS was more frequent in the postmenopausal groups, with 68.4% of women affected ...
Tópico(s): Sleep and related disorders
2015 - Lippincott Williams & Wilkins | Menopause The Journal of The North American Menopause Society
Produção Nacional
Revisado por pares
Thiago de Souza Vilela, Lia Bittencourt, Sérgio Tufik, Gustavo Antônio Moreira,
Sleep deprivation in adolescents has lately become a health issue that tends to increase with higher stress prevalence, extenuating routines, and new technological devices that impair adolescents' bedtime. Therefore, this study aimed to assess the excessive sleepiness frequency and the factors that might be associated to it in this population.The cross-sectional study analyzed 531 adolescents aged 10-18 years old from two private schools and one public school. Five questionnaires were applied: the ...
Tópico(s): Psychosocial Factors Impacting Youth
2015 - Elsevier BV | Jornal de Pediatria
Produção Nacional
Revisado por pares
Helena Hachul, Cristina Frange, Andréia Gomes Bezerra, Camila Hirotsu, Gabriel Natan Pires, Mônica L. Andersen, Lia Bittencourt, Sérgio Tufik,
Objective Our objective was to investigate the influence of menopausal status on sleep patterns in a representative sample of women from São Paulo, Brazil. Study design A population-based survey with a probabilistic three-stage cluster sample of the city of São Paulo was used to represent the local population according to gender, age (20–80 years) and socioeconomic status. Main outcome measures The female participants answered a sleep questionnaire, underwent polysomnographic recording and allowed ...
Tópico(s): Sleep and Wakefulness Research
2014 - Elsevier BV | Maturitas
Produção Nacional
Revisado por pares
Rômulo Lopes Gama, Veralice Meireles Sales de Bruin, Daniel Gurgel Fernandes Távora, Fábio Duran, Lia Bittencourt, Sérgio Tufik,
The objective is to evaluate clinical characteristics and cerebral alterations in Parkinson's disease (PD) patients with diurnal visual hallucinations (VHs). Assessment was performed using magnetic resonance image (MRI) and voxel-based morphometry (VBM). Thirty-nine patients with PD (53.8%) and ten controls were studied. Voxel based morphology analysis was performed. Eleven patients presented diurnal VHs and among these, six had cognitive dysfunction. Patients with VHs performed worse in the mentation- ...
Tópico(s): Spatial Neglect and Hemispheric Dysfunction
2014 - Elsevier BV | Brain and Cognition
Produção Nacional
Revisado por pares
Camila Guindalini, Diego R. Mazzotti, Laura Castro, Carolina Vicaria Rodrigues D’Aurea, Mônica L. Andersen, Dalva Poyares, Lia Bittencourt, Sérgio Tufik,
Previous studies have suggested that brain‐derived neurotrophic factor (BDNF) participates in the homeostatic regulation of sleep. The objective of this study was to investigate the influence of the Val66Met functional polymorphism of the BDNF gene on sleep and sleep EEG parameters in a large population‐based sample. In total 337 individuals participating in the São Paulo Epidemiologic Sleep Study were selected for analysis. None of the participants had indications of a sleep disorder, as measured ...
Tópico(s): Restless Legs Syndrome Research
2014 - Wiley | Journal of Neuroscience Research
Produção Nacional
Revisado por pares
Lenise Jihe Kim, Fernando Morgadinho Santos Coelho, Camila Hirotsu, Lia Bittencourt, Sérgio Tufik, Mônica L. Andersen,
Tópico(s): Sleep and Wakefulness Research
2014 - Springer Science+Business Media | Sleep And Breathing
Produção Nacional
Revisado por pares
Laura Castro, Dalva Poyares, Damien Léger, Lia Bittencourt, Sérgio Tufik,
Using polysomnography, the gold standard for sleep assessment, this study aimed to describe the objective prevalence of insomnia in the São Paulo, Brazil, Epidemiologic Sleep Study cohort of 1,101 adults (20-80 years old).Objective insomnia was defined by meeting 1 of the following criteria: sleep onset latency >30 minutes (sleep initiating insomnia), wake after sleep onset lasting >30 minutes (sleep maintenance insomnia), total sleep time 30 minutes (insomnia with too short duration of sleep or early ...
Tópico(s): Restless Legs Syndrome Research
2013 - Wiley | Annals of Neurology
Produção Nacional
Revisado por pares
Gabriela Matos, Camila Hirotsu, Tathiana A. Alvarenga, Fátima Dumas Cintra, Lia Bittencourt, Sérgio Tufik, Mônica L. Andersen,
Inflammatory markers like tumour necrosis factor-alpha (TNF-α) have been related to erectile dysfunction (ED) and may interact with other cardiovascular risk factors such as obstructive sleep apnoea syndrome (OSAS). The aim of this study was to examine the inflammatory, metabolic and hormonal profile of men with or without ED complaints and/or OSAS recruited through the Epidemiologic Sleep Study (EPISONO). A sample of 363 men completed sexual questionnaires for ED and had physical and blood examinations. ...
Tópico(s): Urinary Bladder and Prostate Research
2013 - Wiley | Andrology
Produção Nacional
Revisado por pares
Sônia Maria Togeiro, Gláucia Carneiro, Fernando Flexa Ribeiro Filho, Maria Teresa Zanella, Rogério Santos‐Silva, Jose Augusto Taddei, Lia Bittencourt, Sérgio Tufik,
Abstract Objective: Epidemiologic studies that control for potential confounders are needed to assess the independent associations of obstructive sleep apnea (OSA) with metabolic abnormalities. The aim of our study was to evaluate the associations of OSA with metabolic abnormalities among the adult population of Sao Paulo, Brazil. Design and Methods: Questionnaires were applied face‐to‐face, full night polysomnography (PSG) was performed, and blood samples were collected in a population‐based survey ...
Tópico(s): Sleep and related disorders
2013 - Wiley | Obesity
Produção Nacional
Revisado por pares
Renata Guedes Koyama, Andrea Maculano Esteves, Luciana Oliveira e Silva, Fábio Santos Lira, Lia Bittencourt, Sérgio Tufik, Marco Túlio de Mello,
This study evaluated the prevalence of, and the risk factors for, obstructive sleep apnea syndrome (OSAS) among Brazilian railroad workers. Male railroad workers (745) from a railway company in Brazil were analyzed after responding to questionnaires about their demographics, sleep habits, excessive daytime sleepiness (Epworth), and the likelihood of having apnea (Berlin). We also performed polysomnography and measured anthropometric data for all of the railroad workers. The results showed that 261 (35. ...
Tópico(s): Neuroscience of respiration and sleep
2012 - Elsevier BV | Sleep Medicine
Produção Nacional
Revisado por pares
Lígia Gabrielle Santos, Gabriel Natan Pires, Lia Bittencourt, Sérgio Tufik, Mônica L. Andersen,
Despite the knowledge concerning the pathogenesis of tuberculosis, this disease remains one of the most important causes of mortality worldwide. Several risk factors are well-known, such poverty, HIV infection, and poor nutrition, among others. However, some issues that may influence tuberculosis warrant further investigation. In particular, the chronobiological aspects related to tuberculosis have garnered limited attention. In general, the interface between tuberculosis and chronobiology is manifested ...
Tópico(s): Tuberculosis Research and Epidemiology
2012 - Elsevier BV | Tuberculosis