Edward Helmore, Michael Prescott, Barbara Hall, General H Norman Schwarzkopf, Paul Nelson, Virginia Bottomley, Helen Davidson, Philip Norman, Rob Hughes, John Peter, Mark Reason, Jonathan Miller, Graham Lees, Eric Dymock, Lesley White, Barbara Ellis, Tony Francis, Susan d'Arcy, Tony Parsons, Stephen Bayley, Frank Whitford, Graham Rose, Sheridan Morley, Christa D'souza, Diana Wright Personal Finance Editor, David McErlain, Kirstle Hamilton, Alistair Scott, Sally Payne, David Smith, Nick Pitt, Martin Brundle, Edward Welsh, Carol Sarler, Carl Hindmarch, Geordie Greig, Tony Allen-Mills, Charles Murray, Martin James, Robert Sandall, Iain Johnstone, Boris Yeltsin, Nilgin Yusuf, Irwin Stelzer, Robert Hewison, Ivan Fallon, Deryk Brown, David Dougill, Alan Bergson, Peter Reading, John Gribbin, Vivienne Savory, Harvey Porlock, Hugh Canning, Peter Kemp, Kitsch Crystal, Melanie Hunter, Sean Ryan, Michael Jones, John Chawner, Caroline Lees, Peter Millar, Brian Morton, Peter Kellner, George Perry, John Cassidy, Sue Mott, Mark Skipworth, Philip Robinson, Harry Ritchie, J Beacon, Paul Golding, Christine Toomey, Bernard Cafferty, Paul Donovan, Peter Hounam, Peter Lewis, Simon Mills, Michael Prescot, Jeff Randall, James Adams, Richard Dawkins, Robin Carrell, Janine di Glovanni, Tim Rayment, Peter Plant, Martin Jones, Tom Shone, Janet Daley, Rufus Olins, Tavleen Singh, Bryan Gould, David Lawrenson, David Field, Ira Miller, Richard Rosenfeld, Christopher Lloyd, James Brown, Brian Reading, John Karter, Barbara Amiel, Malcolm Winton, Terry Finerty, Richard Cook, Craig Brown, Diana Wright, Jean-Paul Gaultier, Stephen Jones, Jonathan Coe, Andrew Grice Chief Political Correspondent, Ken Shuttleworth, Reger Williams, Andrew Neil, Richard Palmer, Nick Hornby, Andrew Grice, Carolione Lees Arts Correspondent, Martin Searby, Ian Birrell, David Torvell, Marcel Berlins, Lanny Bezant, Ray Monk, Polly Samson, Nick MacKinnon, Andrew Hogg, A Pedder, Clive Everton, Garth Alexander, Peter Johnson, Rupert Morris, P Wilkins, Mitchell Symons, Leon Sanders, Michael Kallenbach, Brian Moore, Elizabeth Shrimpton, Rebecca Fowler, Palricia Fenn, Michael Jones Political Editor, Ian Penman, Julie Burchill, Andrew Yates, David Hunn, Mihir Bose, Simon Callow, Matthew Lynn, Eve Arnold, Hugh Fearnley-Whittingstall, Simon Watson, Stuart Welling, Roy Hattersley, Matthew Campbell, Bryan Appkeyard, Stan Levenson, Norman Macrae, Chris Dighton, Chris Tame, Godfrey Golzen, Gilbert Adair, Tony Hall, Patricia Fenn, Andrew Lorenz, John Furbisher, Chanteuse, Kim Andreoli, Chris Lightbown, Jeff Randall City Editor, Hugh Pearman, Rufus Ollns, Angela Huth, John Kohut, George Racz, Neil MacLean, Penny Perrick, Tony Hetherington, Anthony Howard, Joanna Simon, Douglas Dunn, Iain Jenkins, Danny Danziger, Rebecca Mead's, Matthew Crabbe, Boris Schapiro,
... by Edward Helmore Picture Gallery Those Guys on? Sergio Tacchini On all fours The four-wheel-drive ...
1992 - Gale Group | Sunday Times HA GDA
Fungyi Chow, Juan Macchiavello, Sergio Santa Cruz, Erika Fonck, Jorge Olivares,
... for more papers by this authorSergio Santa Cruz, Sergio Santa Cruz Facultad de Ciencias del Mar. Universidad Católica del ... for more papers by this authorSergio Santa Cruz, Sergio Santa Cruz Facultad de Ciencias del Mar. Universidad Católica del ...
Tópico(s): Marine and coastal plant biology
2001 - Wiley | Journal of the World Aquaculture Society
Giles Smith, Andrew Robson, Christina Hardyment, John McNamara, Dan Cruickshank, Robert Cole, Bel Mooney, David Brown, Alexandra Frean, Matt Spence, F. G. Cottam, Tom Dyckhoff, Frances Gibb Legal Editor, Amanda Ursell, Simon Barnes, David Aaronovitch, Jane MacQuitty, Lloyd Bradley, Peter Lansley, Kathleen Wyatt Travel Editor, Simon Hills, Robert Lindsay, Lionel Shriver, 50, Author and Journalist, Stephen Bayley, John Mulvey, Sarah Urwin Jones, Alexandra Frean Education Editor, Kate Quill Assistant Travel Editor, Emma Cook, Tony Turnbull, Philip Howard, Carol Midgley, David Lister Scotland Correspondent, Christine Seib, David Chater, Kate Wighton, James Ducker, Rachel Campbell-Johnston, Melissa Katsoulis, Clive Davis, Dan Kieran, Gabrielle Starkey, Lucia Van Der Post, Jane Taylor-Hayhurst, Will Pavia, Lauren Thompson, Margaret Sandiford, James Hider, Tristram Hunt, Hilly Janes Editor, Kevin Eason, Wendy Ide, John Bungey, Lucy Bannerman, Andrew Norfolk, Robin Pagnamenta, Giles Coren, Vivienne Parry, Sathnam Sanghera, Dr Copperfield, Anthony Burns, Dr Adam P Fitzpatrick, John Clarke, Jane MacArtney, Vinny Lee, Hannah Fletcher, A. S. H. Smyth, Siobhan Kennedy, Francis Elliott, David Byers, Madeline Thomas, Jack Malvern, Dan Sabbagh Media Editor, Debra Craine, Amanda Owens, Ruth Corbett, John Tiffany, Tom Charity, Allan Simmons, Robina Manger, Daniel Finkelstein, Rosemary Bennett, Tim Reid, Jeanette Winterson, Dan Sabbagh, Dalya Alberge Arts Correspondent, Dolly Daniel, Allan Wyatt, Tom Gatti, Jo Morris, Kevin Dolak, Sophie Harris, Marion Carr, Andrew Ellson Personal Finance Editor, David Hands, Nicky Hambleton-jones, Charles Bremner, Chris Johnston, Thamoasina Miers, Ian Collins, Helen Rumbelow, Ben MacHell, Jonathan Sacks, Lucy Sweeney, Tim Teeman, Lilly Peel, Hugo Rifkind, Derwent May, James Mottram, Angela Jameson, Kate Muir, Peter Carrington, Salman Rushdie, Aggie MacKenzie, Russell Kempson, Robert Crompton, Emma Mahony, Sue Fox, Ed Potton, Gary Duncan Economics Editor, George Rae, Stephen Anderton, Sarah Vine, Mark Atherton, Lisa Armstrong, John Westerby, Jane Wheatley, Rebecca O'connor Troubleshooter, Debby Wakeham, Morgan Falconer, Douglas Rankine, Sally Baker, John Stanning, Pete Paphides, Sheera Frenkel, Rob Wright, Christina Koning, Carla Power, Natalie Haynes, Edward Gorman Motor Racing Correspondent, Neil Harman Tennis Correspondent, Victoria Lambert, Raymond Keene, Ken Howard, Adam Sage, Sean O'Neill Crime and Security Editor, Suzi Godson, Lewis Smith, John Russell Taylor, Kate Saunders, Matt Hughes, Rebecca O'Connor, Peter McGeown, Gordon Ramsay, Camilla Hempleman-Adams, Bruce Dessau, Dr Keith Hopcroft, Sean O'Neill, Lewis Smith Environment reporter, Kaveh Solhekol, Nigel Hawkes, Roger Phillips, Rick Jones, Andrew G. Marshall, Chris Campling, Emily Monk, Adam Fresco Crime Correspondent, Patrick Hosking, Richard Owen, Ross Leckie, Erica Wagner, Roger Boyes, James Charles, Sarah Wootton, Air Vice-Marshal Barry Higgs, Peter Dixon, Thomasina Miers, Peter Neall, Jonathan Luxmoore, Margaret Reynolds, Fu Ying, David Hands Rugby Correspondent, Rosemary Bennett Social Affairs Correspondent, Julian Muscat, Paul Simons, Kevin Maher, Mike Mulvihill, Nicholas Clee, Steve Jelbert, Nigel Kendall, David Byrnand, Dominic Kennedy, Dearbáil Jordan, Joanna Pitman, Philip Webster Political Editor, Sam Coates Chief Political Correspondent, Richard Ehrlich, Steve Hawkes, Lord Skidelsky, Dominic Maxwell, Steophen Dalton, Prue White, Matthew Parris, Mark Bridge, Gabriele Starkey, Michael Moran, Amanda Craig, Tim Wapshott, Caitlin Moran, Sheila Keating, Alan Lee, Neil Fisher, Iain Finlayson, Stuart pace, Ben MacIntyre, Jeremy Page South Asia Correspondent, Anna Dixon, Bess Twiston Davies, George Clooney, David Sinclair, John Naish, Catherine Philp, Martin Waller, Mark Henderson, James Jackson, Patrick Foster, Nigel Hawkes Health Editor, Ashling O'Connor, Anna Shepard, Benedict Nightingale, Louise Cohen, Brian Logan, Dr Thomas Stuttaford, Stephen Dalton, Ben Hoyle, The Rev Michael Bentley, Alyson Rudd, Frances Gibb, Tom Chesshyre, Tony Halpin, Alice Miles, Robert Cole Personal Investor, Chris Moore, James Christopher, Richard Morrison, Simon Crompton, Michael Evans, Alan Lee Racing Correspondent, Lisa Tuttle, Alan Jackson, Steve Hawkes Retail Correspondent, Tobias Hill, Kim Newman, Miles Costello, Jan Raath, David Robertson, Steve Keenan Online Travel Editor, Richard Hammond,
... Runway Sky One, 8pm Gossip Girl ITV2, 10pm Sergio Leone: Once Upon a Time Sky Arts, 10pm ...
2008 - Gale Group | TDA
Produção Nacional
Revisado por pares
Maria Regiane Araújo Soares, Cristiane Costa Carvalho, Lucileine Amorim Silva, Mauro Sérgio Cruz Souza Lima, Aldina Barral, José Manuel Macário Rebêlo, Silma Regina Ferreira Pereira,
O objetivo deste estudo foi investigar a infecção natural por Leishmania chagasi em flebotomíneos capturados em focos de leishmanioses visceral (LV) na ilha de São Luís, Maranhão, Brasil. Análise molecular por reação em cadeia da polimerase (PCR) foi aplicada para determinar a taxa de infecção natural de Lutzomyia longipalpis por L. chagasi em áreas de ocupação humana antiga e recente, na ilha de São Luís. Valendo-se de uma amostra de 800 fêmeas coletadas no período de março a agosto de 2005, foi ...
Tópico(s): Trypanosoma species research and implications
2010 - Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz | Cadernos de Saúde Pública
By Clive Borrell and Christopher Sweeney, From Robert Fisk, From Peter Nichols in Rome and Patrick Brogan in New York, From Our Correspondent, By Paul Routledge Labour Correspondent, By George Clark Political Staff, By Stewart Tendler, By Our Political Editor, By Paul Routledge, By John Roper Medical Reporter, From Robert Fisk Belfast, Feb 20, By Frank Roberts Local Government Correspondent, By a Staff Reporter, By Frank Roberts Our Local Government Correspondent, By Michael Baily Transport Correspondent, By Pat Healy Social Services Correspondent, From Christopher Warman, From Arthur Osman, By Martin Huckerby, By Our Horticultural Correspondent, By Arthur Reed Air Correspondent, From David Cross, From Our Own Correspondent, From Richard Wigg, From Edward Mortimer, By Our Diplomatic Correspondent, From Ian McDonald, From Paul Martin, From Our Correspondent Athens, Feb 20, From Philip Short, From David Bonavia, Victor E. Neuburg, Hugh Jolly, By Neil Allen Boxing correspondent, By Peter West Rugby Correspondent, By Peter Ryde Golf Correspondent, By Our Rackets Correspondent, By Michael Phillips Racing Correspondent, Stanley Sadie, Irving Wardle, Joseph Wechsberg, Keith Horner, Stanley Reynolds, Leonard Buckley, Michael Wale, Max Harrison, Richard Crossman, C. D. Foster, A. M. Rendel Diplomatic Correspondent, PHS, Edward Mortimer, SYBIL ROSENFELD., GEOFFREY CHANDLER, , D. L. BLAY, , G. CUNNINGHAM, JOHN HORAM, , W. N. EWER, , GORDON WARD., ALBAN CAROE, G. G. STEWART., JUAN P. CRUZ, , RONALD BUTT, , GERARD NOEL, J. C. AMBLER, , C.L. HOWELL THOMAS, , BASIL BOOTHROYD, GLORIA CIGMAN, , JANE MANLEY., Keith Gore, By Maurice Corina Industrial Editor, By Roger Vielvoye, By Peter Hill, By Christopher Wilkins, By Ian Morison, By Melvyn Westlake, By Clifford Webb, By R. W. Shakespeare Northern Industrial Correspondent, By Andrew Goodrick-Clark, BY THE FINANCIAL EDITOR, From Frank Vogl, By Guy Hawtin, F. A. PULLINGER, , R. N. BOWES, F. G. BERNAYS, , JULIA L. PARKER, , ISABEL GARFORD, , R. BARNES, , G. A. HARMAN, , W. M. FORREST, , Peter Hill, Geoffrey Bell, Patricia Tisdall, John Whitmore, Andrew Wilson, Le Monde, La Stampa, The Times, Die Welt, Jacques-Francois Simon Le Monde, Lamberto Furno La Stampa, Jörg Foshag Die Welt, Tony Aldous The Times, by John Ardagh, by Tony Aldous, by Mario Salvatorelli La Stampa, by Etienne Mallet Le Monde, by Jan Brech Die Welt, by Francois Grosrichard Le Monde, by Sergio Devecchi La Stampa, by Hans Stollhans Die Welt, Vittorio Zucconi La Stampa, by Philippe Lemaitre Le Monde,
News: Police hunt fails to trace Petain coffin, Ulster poll is against extremist politicians, Currency upheavals cause delay in EEC's farm review, Mr ...
1973 - Gale Group | TDA
Josef E. Herz, M. Sergio Cruz, J.V. Torres, Arturo Murillo,
Abstract Esters of 17α-ethinyl-19-nortestosterone (19-NET) and hindered acids are potentially useful as long-acting anticonceptive agents. No satisfactory method for the prepara-
Tópico(s): Inflammatory mediators and NSAID effects
1977 - Taylor & Francis | Synthetic Communications
Manoel Messias Pereira da Silva, Hernán Vásquez, Ricardo Bressan‐Smith, José Fernando Coelho da Silva, Eleonora D'Ávila Erbesdobler, Paulo Sérgio Cruz de Andrade,
Neste estudo, as espécies capim-setária (Setaria anceps Stapf.), capim-hemárthria (Hemarthria altissima [Poir] Stapf. & Hubbard), capim-do-nilo (Acroceras macrum Stapf.) e capim-angola (Brachiaria purpurascens [Raddi] Henr.) foram submetidos à deficiência hídrica moderada a seca com o objetivo de avaliar o efeito do déficit hídrico sobre as características de fluorescência da clorofila. O experimento foi realizado em casa de vegetação, em blocos ao acaso, constituídos pelas quatro espécies cultivadas sob ...
Tópico(s): Bioenergy crop production and management
2006 - Sociedade Brasileira de Zootecnia | Revista Brasileira de Zootecnia
Sergio Cruz-Blázquez, David Ruiz,
Abstract In this paper, we consider the problem of prescribing the Gaussian and geodesic curvature on a disk and its boundary, respectively, via a conformal change of the metric. This leads us to a Liouville-type equation with a non-linear Neumann boundary condition. We address the question of existence by setting the problem in a variational framework which seems to be completely new in the literature. We are able to find minimizers under symmetry assumptions.
Tópico(s): Advanced Mathematical Modeling in Engineering
2018 - De Gruyter | Advanced Nonlinear Studies
Fanzhu Kong, Cheng‐Hung Tsai, Fu-Sheng Tsai, Wenyi Huang, Sergio Cruz,
The purpose of this study is to conduct a wide-ranging meta-analytic review of empirical psychological capital studies in the management field. We conducted a meta-analysis on papers collected from the EBSCOhost and ProQuest databases. For comprehensive and extensive literature coverage, we also searched and compared the Journal Citation Report for the journals that referenced the most-cited articles (e.g., Journal of Organizational Behavior, Academy of Management Journal, etc.). A total of 81 published ...
Tópico(s): Psychological Well-being and Life Satisfaction
2018 - Multidisciplinary Digital Publishing Institute | Sustainability
Produção Nacional
Revisado por pares
Antonio Sérgio Cruz Gaia, Pablo Henrique Caracciolo Gomes de Sá, Mônica Silva de Oliveira, Adonney Allan de Oliveira Veras,
Abstract The Next-Generation Sequencing (NGS) platforms provide a major approach to obtaining millions of short reads from samples. NGS has been used in a wide range of analyses, such as for determining genome sequences, analyzing evolutionary processes, identifying gene expression and resolving metagenomic analyses. Usually, the quality of NGS data impacts the final study conclusions. Moreover, quality assessment is generally considered the first step in data analyses to ensure the use of only reliable ...
Tópico(s): Molecular Biology Techniques and Applications
2019 - Nature Portfolio | Scientific Reports
Diana Gabriela Robinson Trápaga, Isis Arlene Díaz Carrión, Sergio Cruz Hernández,
La organización de las mujeres indígenas y rurales en grupos productivos y microempresas pretende ser un mecanismo hacia el empoderamiento, combate a la pobreza, y equidad de género, los tres son Objetivos de Desarrollo Sostenible de la Agenda para el Desarrollo al 2030 de las Naciones Unidas (PNUD, 2017); en México, dichos objetivos se abordan desde el Plan Nacional de Desarrollo, PND (2013-2018), donde además se establece como estrategia transversal la perspectiva de género para ser aplicada en ...
Tópico(s): Family Business Performance and Succession
2019 - Politecnica Salesiana University | Retos
Sergio Cruz-León, Nadine Schwierz,
A large variety of physicochemical properties involving RNA depends on the type of metal cation present in solution. In order to gain microscopic insight into the origin of these ion specific effects, we apply molecular dynamics simulations to describe the interactions of metal cations and RNA. For the three most common ion binding sites on RNA, we calculate the binding affinities and exchange rates of eight different mono- and divalent metal cations. Our results reveal that binding sites involving ...
Tópico(s): RNA Research and Splicing
2020 - American Chemical Society | Langmuir
Corina Benjet, Andrea K. Wittenborn, Raúl A. Gutiérrez–García, Yesica Albor, Eunice Vargas Contreras, Sergio Cruz Hernández, Karla Patricia Valdés‐García, Iris Rubí Monroy Velasco, Álvaro J. Peláez Cedrés, Praxedis Cristina Hernández Uribe, Anabell Covarrubias Díaz-Couder, Guillermo E. Quevedo Chávez, María Abigal Paz-Peréz, María Elena Medina‐Mora, Ronny Bruffaerts,
Purpose Although Internet-based electronic health (eHealth) interventions could potentially reduce mental health disparities, especially in college students in under-resourced countries, little is known about the relative acceptability of eHealth versus in-person treatment modalities and the treatment barriers associated with a preference for one type over the other. Methods Participants were from the 2018–2019 cohort of the University Project for Healthy Students (PUERTAS), a Web-based survey of ...
Tópico(s): Mental Health Research Topics
2020 - Elsevier BV | Journal of Adolescent Health
Sergio Cruz-León, Tomáš Majtner, Patrick C. Hoffmann, Jan Philipp Kreysing, Sebastian Kehl, Maarten W. Tuijtel, Stefan L. Schaefer, Katharina Geißler, Martin Beck, Beata Turoňová, Gerhard Hummer,
Abstract Visual proteomics attempts to build atlases of the molecular content of cells but the automated annotation of cryo electron tomograms remains challenging. Template matching (TM) and methods based on machine learning detect structural signatures of macromolecules. However, their applicability remains limited in terms of both the abundance and size of the molecular targets. Here we show that the performance of TM is greatly improved by using template-specific search parameter optimization ...
Tópico(s): RNA and protein synthesis mechanisms
2024 - Nature Portfolio | Nature Communications
Sergio Cruz-León, Kara K. Grotz, Nadine Schwierz,
Magnesium and calcium play an essential role in the folding and function of nucleic acids. To correctly describe their interactions with DNA and RNA in biomolecular simulations, an accurate parameterization is crucial. In most cases, the ion parameters are optimized based on a set of experimental solution properties such as solvation free energies, radial distribution functions, water exchange rates, and activity coefficient derivatives. However, the transferability of such bulk-optimized ion parameters ...
Tópico(s): Protein Structure and Dynamics
2021 - American Institute of Physics | The Journal of Chemical Physics
Kara K. Grotz, Sergio Cruz-León, Nadine Schwierz,
Magnesium ions play an essential role in many vital processes. To correctly describe their interactions in molecular dynamics simulations, an accurate parametrization is crucial. Despite the importance and considerable scientific effort, current force fields based on the commonly used 12–6 Lennard-Jones interaction potential fail to reproduce a variety of experimental solution properties. In particular, no parametrization exists so far that simultaneously reproduces the solvation free energy and ...
Tópico(s): Protein Structure and Dynamics
2021 - American Chemical Society | Journal of Chemical Theory and Computation
Sergio Cruz-León, Nadine Schwierz,
The distribution of cations around nucleic acids is essential for a broad variety of processes ranging from DNA condensation and RNA folding to the detection of biomolecules in biosensors. Predicting the exact distribution of ions remains challenging since the distribution and, hence, a broad variety of nucleic acid properties depend on the salt concentration, the valency of the ions, and the ion type. Despite the importance, a general theory to quantify ion-specific effects for highly charged biomolecules ...
Tópico(s): Nanopore and Nanochannel Transport Studies
2022 - American Chemical Society | The Journal of Physical Chemistry B
Sergio Cruz-León, Willem Vanderlinden, Peter Müller, Tobias Förster, Georgina Staudt, Yi-Yun Lin, Jan Lipfert, Nadine Schwierz,
Abstract The structure and properties of DNA depend on the environment, in particular the ion atmosphere. Here, we investigate how DNA twist -one of the central properties of DNA- changes with concentration and identity of the surrounding ions. To resolve how cations influence the twist, we combine single-molecule magnetic tweezer experiments and extensive all-atom molecular dynamics simulations. Two interconnected trends are observed for monovalent alkali and divalent alkaline earth cations. First, ...
Tópico(s): Bacteriophages and microbial interactions
2022 - Oxford University Press | Nucleic Acids Research
Seyed Mohammad Mahdi Moosavi, Jawad Faiz, Mohsen Bandar Abadi, Sérgio M. A. Cruz,
... more papers by this authorSergio M.A. Cruz, Sergio M.A. Cruz orcid.org/0000-0002-9651-8925 Department of ... more papers by this authorSergio M.A. Cruz, Sergio M.A. Cruz orcid.org/0000-0002-9651-8925 Department of ...
Tópico(s): Electric Motor Design and Analysis
2018 - Institution of Engineering and Technology | IET Electric Power Applications
Produção Nacional
Revisado por pares
Natasha Ferreira Santos da Cruz, Larissa Silva Brandão, Sérgio Ferreira Santos da Cruz, Sergio Escribano Cruz, Carla Andréa Avelar Pires, Francisca Regina Oliveira Carneiro,
We aimed to report the ocular manifestations observed in patients with psoriasis.Patients were included and referred to our ophthalmology clinic from dermatology clinics of Universidade do Estado do Pará between October 2013 and August 2014. Clinical interviews were conducted to identify relevant epidemiological data, clinical features, and treatment details, and data were recorded using the same protocol. Subsequent dermatological examinations were performed and disease severity was rated using ...
Tópico(s): Acne and Rosacea Treatments and Effects
2018 - Conselho Brasileiro de Oftalmologia | Arquivos Brasileiros de Oftalmologia
Produção Nacional
Revisado por pares
Luís Mesquita Sousa-Filho, Cléverson D.T. Freitas, Marina Duarte Pinto Lobo, Ana Cristina de Oliveira Monteiro‐Moreira, Renan O. Silva, Lucas de Araújo Bastos Santana, Ronaldo A. Ribeiro, Marcellus Henrique Loiola Ponte de Souza, Gustavo Portela Ferreira, Anna Carolina Toledo da Cunha Pereira, André Luiz dos Reis Barbosa, Mauro Sérgio Cruz Souza Lima, Jefferson Soares de Oliveira,
Parotoid glands of amphibians are known for the production of several biologically active compounds having pharmacological and toxic effects in mammals. In the present work, a protein fraction obtained from Rhinella schneideri parotoid gland (RsPP) was characterized to study its biological and toxic effects. Rhinella schneideri parotoid secretion is composed of up to 30% (w/w) of soluble proteins. Tandem mass spectrometric analysis of the RsPP identified 104 proteins, including actin, beta-actin, ...
Tópico(s): Galectins and Cancer Biology
2016 - Wiley | Journal of Experimental Zoology Part A Ecological Genetics and Physiology
With the recent development of wearable cameras, the interest for research on the egocentric perspective is increasing. This opens the possibility to work on a specific object detection problem of hand detection and hand disambiguation. However, recent progress in egocentric hand disambiguation and even hand detection, especially using deep learning, has been limited by the lack of a large dataset, with suitable variations in subject, activity, and scene. In this paper, we propose a dataset that ...
Tópico(s): Advanced Neural Network Applications
2019 - Elsevier BV | Image and Vision Computing
Produção Nacional
Revisado por pares
Mauro Sérgio Cruz Souza Lima, Jonas Pederassi, R. B. Pineschi, Diogo Brunno e Silva Barbosa,
Vocalizations are an important trait for the identification of cryptic and/or closely related amphibian species. Different vocalizations also contribute to partitioning of the acoustic space by sympatric species. This study aimed to describe the advertisement calls of anurans in a pond of the municipality of Floriano, State of Piauí, Brazil, and infer the acoustic niche partitioning of amphibians. Euclidean distance was used in a cluster analysis approach to infer the acoustic similarities among ...
Tópico(s): Animal Behavior and Reproduction
2018 - Instituto Internacional de Ecologia (Brazil) | Brazilian Journal of Biology
Maarten W. Tuijtel, Sergio Cruz-León, Jan Philipp Kreysing, Sonja Welsch, Gerhard Hummer, Martin Beck, Beata Turoňová,
Cryo-electron tomography (cryo-ET) is a powerful method to elucidate subcellular architecture and to structurally analyze biomolecules in situ by subtomogram averaging, yet data quality critically depends on specimen thickness. Cells that are too thick for transmission imaging can be thinned into lamellae by cryo-focused ion beam (cryo-FIB) milling. Despite being a crucial parameter directly affecting attainable resolution, optimal lamella thickness has not been systematically investigated nor the ...
Tópico(s): Seismic Imaging and Inversion Techniques
2024 - American Association for the Advancement of Science | Science Advances
Sergio Cruz-León, Álvaro Vázquez‐Mayagoitia, Simone Melchionna, Nadine Schwierz, Maria Fyta,
A coarse-grained model for simulating structural properties of double-stranded RNA is developed with parameters obtained from quantum-mechanical calculations. This model follows previous parametrization for double-stranded DNA, which is based on mapping the all-atom picture to a coarse-grained four-bead scheme. Chemical and structural differences between RNA and DNA have been taken into account for the model development. The parametrization is based on simulations using density functional theory ( ...
Tópico(s): DNA and Nucleic Acid Chemistry
2018 - American Chemical Society | The Journal of Physical Chemistry B
María Luna‐Luna, Sergio Críales-Vera, Diana Jhoseline Medina-Leyte, Mariana Díaz‐Zamudio, Adriana Flores-Zapata, David Cruz‐Robles, Mauricio López‐Meneses, Sergio Olvera-Cruz, Samuél Ramírez-Marroquín, Cristóbal Flores‐Castillo, José Manuel Fragoso, Elizabeth Carreón‐Torres, Jesús Vargas‐Barrón, Gilberto Vargas‐Alarcón, Óscar Pérez‐Méndez,
It has been proposed that the cardiovascular effects of obesity are related to epicardial adipose tissue (EAT), which seems to play an active role on the development and calcification of atherosclerotic plaques, but the mechanisms are still unknown. Therefore, the aim of this study was to determine whether the EAT expresses the genes of calcifying factors and whether such expression is associated with the body mass index (BMI) and with the presence of coronary artery calcium (CAC) in patients with ...
Tópico(s): Connective tissue disorders research
2020 - Dove Medical Press | Diabetes Metabolic Syndrome and Obesity
Ulises De la Cruz-Mosso, Trinidad García‐Iglesias, Richard Bucala, Iris Estrada‐García, Laura González-López, Sergio Cerpa‐Cruz, Isela Parra‐Rojas, Jorge Iván Gámez-Nava, Edsaúl Emilio Pérez-Guerrero, José Francisco Muñoz‐Valle,
Macrophage migration Inhibitory Factor (MIF) is a cytokine associated with the pathogenesis of autoimmune inflammatory diseases. There is evidence that MIF functions in a positive-feedback-loop with proinflammatory cytokines and could perpetuate the inflammatory process in Systemic Lupus Erythematosus (SLE).The aim of this study was to assess the effect of recombinant-human-MIF (rhMIF) on the expression of Th1, Th2 and Th17 cytokines in Peripheral Blood Mononuclear Cells (PBMC) from Healthy Subjects ( ...
Tópico(s): Galectins and Cancer Biology
2017 - Elsevier BV | Cellular Immunology
Produção Nacional
Revisado por pares
Manoel Messias Pereira da Silva, Hernán Vásquez, Ricardo Bressan‐Smith, José Fernando Coelho da Silva, Eleonora D'Ávila Erbesdobler, Paulo Sérgio Cruz de Andrade,
Quatro gramíneas forrageiras (Setaria anceps Stapf., Hemarthria altissima [Poir] Stapf. & Hubbard, Acroceras macrum Stapf. e Brachiaria purpurascens [Raddi] Henr.), foram estabelecidas por mudas, em vasos plásticos com diferentes condições hídricas, para se avaliar algumas características morfogênicas e estruturais. As irrigações foram controladas pela pesagem individual dos vasos e pela saturação relativa à porosidade total (SRPT) para cada nível hídrico do solo. Utilizou-se o delineamento de blocos ...
Tópico(s): Soil Carbon and Nitrogen Dynamics
2005 - Sociedade Brasileira de Zootecnia | Revista Brasileira de Zootecnia
Sergio Cerpa‐Cruz, Patricia Paredes-Casillas, Erika‐Paola Navarro, Ana Guilaisne Bernard‐Medina, G. Martínez-Bonilla, Sergio Gutiérrez‐Ureña,
Tópico(s): Rheumatoid Arthritis Research and Therapies
2013 - Springer Science+Business Media | Immunologic Research
Luis Alexis Hernández-Palma, Samuel García‐Arellano, Richard Bucala, Mara Anaís Llamas-Covarrubias, Ulises De la Cruz-Mosso, Edith Oregón-Romero, Sergio Cerpa‐Cruz, Isela Parra‐Rojas, Arturo Plascencia-Hernández, José Francisco Muñoz‐Valle,
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by elevated levels of pro-inflammatory cytokines, such as interleukin (IL)-6, IL-17, and macrophage migration inhibitory factor (MIF). MIF induces IL-17 secretion and MIF promoter polymorphisms influence the expression of selected downstream mediators. The aim of this study was to investigate the relationship between known functional MIF haplotypes and Th17-related cytokine secretion profile in peripheral blood mononuclear ...
Tópico(s): Nuclear Receptors and Signaling
2018 - Elsevier BV | Cytokine