Produção Nacional
Revisado por pares
Estevan Eltink, Eliseu Vieira Dias, Sérgio Dias‐da‐Silva, César Leandro Schultz, Max C. Langer,
Stereospondyls are a diverse and morphologically distinctive clade of basal tetrapods that rapidly reached a global distribution and high abundance during the Early Triassic. Yet, the first stereospondyls appeared in the Middle-Late Permian of Gondwana, mostly represented by Rhinesuchidae. Australerpeton cosgriffi is a long-snouted representative of the group and one of the most complete temnospondyls known from the Permian of South America. The elements attributed to Au. cosgriffi were recovered ...
Tópico(s): Evolution and Paleontology Studies
2015 - Oxford University Press | Zoological Journal of the Linnean Society
Francisco Caiado, Tânia Carvalho, Isadora Rosa, Leonor Remédio, Ana Costa, João Matos, Beate Heissig, Hideo Yagita∥, Koichi Hattori, João Pereira da Silva, Paulo Fidalgo, António Dias Pereira, Sérgio Dias,
Timely detection of colorectal cancer metastases may permit improvements in their clinical management. Here, we investigated a putative role for bone marrow-derived cells in the induction of epithelial-to-mesenchymal transition (EMT) as a marker for onset of metastasis. In ectopic and orthotopic mouse models of colorectal cancer, bone marrow-derived CD11b(Itgam)(+)Jagged2 (Jag2)(+) cells infiltrated primary tumors and surrounded tumor cells that exhibited diminished expression of E-cadherin and increased ...
Tópico(s): Wnt/β-catenin signaling in development and cancer
2013 - American Association for Cancer Research | Cancer Research
Produção Nacional
Revisado por pares
Sérgio Dias‐da‐Silva, Sérgio Furtado Cabreira, Lúcio Roberto da Silva,
The first occurrence of stereospondyl remains in the Santa Maria Formation (Middle/Upper Triassic) of the Paraná Basin is reported. The material is fragmentary but indicates the presence of large stereospondyls in the Carnian of this unit. The lack of informative characters is an obstacle, but the specimens probably belong to metoposaurids, trematosaurids or mastodonsauroids. Most South American reports of stereospondyls record fragmentary remains (except for the Argentinean chigutisaurids, and the ...
Tópico(s): Ichthyology and Marine Biology
2010 - Taylor & Francis | Alcheringa An Australasian Journal of Palaeontology
Produção Nacional
Revisado por pares
Sérgio Dias‐da‐Silva, Dhurjati Prasad Sengupta, Sérgio Furtado Cabreira, Lúcio Roberto da Silva,
Abstract: Chigutisauridae is the longest‐lived trematosaurian clade (from early Triassic to early Cretaceous). They were reported in Argentina, Australia, India and South Africa. This contribution reports a putative chigutisaurid specimen in the Carnian of southern Brazil (Santa Maria Formation, Paraná Basin). The material comprises two skull fragments, a mandibular fragment, a clavicular blade and a humerus. Ontogenetic features point to an early development stage of the specimen. The presence of ...
Tópico(s): Ichthyology and Marine Biology
2011 - Wiley | Palaeontology
Produção Nacional
Frederico Teixeira, Sérgio Dias do Couto Netto, André Luis de Freitas Perina, Fábio César Miranda Torricelli, Luciana Ragazzo Teixeira, Antônio Eduardo Zerati, Fábio de Oliveira Ferreira, Eduardo Hiroshi Akaishi, Sérgio Carlos Nahas, Edivaldo Massazo Utiyama,
Leiomyosarcoma (LMS) of inferior vena cava (IVC) is a rare neoplasm affecting approximately 1/100,000 people. The prognosis is poor and potential curative intent occurs through challenging operations, such as vena cava resection, occasionally multivisceral when required, and vascular reconstruction. There are few retrospective series regarding this retroperitoneal neoplasm, and the aim of the present study was to discuss the experience at the São Paulo Cancer Institute and Clinics Hospital of University ...
Tópico(s): Vascular Tumors and Angiosarcomas
2017 - Spandidos Publishing | Oncology Letters
... Marco Aurélio Gallo de França, Sérgio Furtado Cabreira, Sérgio Dias-Da-Silva An impressive skeleton of the giant ...
Tópico(s): Evolution and Paleontology Studies
1915 - University of Chicago Press | The Journal of Geology
Produção Nacional
Revisado por pares
João Victor de Oliveira Santos, Sérgio Dias da Costa Júnior, Sandrelli Meridiana de Fátima Ramos dos Santos Medeiros, Iago Dillion Lima Cavalcanti, Jaqueline Barbosa de Souza, Davi de Lacerda Coriolano, Wagner Roberto Cirilo da Silva, Maria Helena Menezes Estevam Alves, Isabella Macário Ferro Cavalcanti,
Antimicrobial resistance (AMR) represents a critical obstacle to public health worldwide, due to the high incidence of strains resistant to available antibiotic therapies. In recent years, there has been a significant increase in the prevalence of resistant epidemic strains, associated with this, public health authorities have been alarmed about a possible scenario of uncontrolled dissemination of these microorganisms and the difficulty in interrupting their transmission, as nosocomial pathogens ...
Tópico(s): Bacterial Identification and Susceptibility Testing
2022 - Springer Science+Business Media | Current Microbiology
Produção Nacional
Revisado por pares
Tiane Macedo de Oliveira, Felipe L. Pinheiro, Átila Augusto Stock Da‐Rosa, Sérgio Dias‐da‐Silva, Leonardo Kerber,
After the Permo-Triassic mass extinction, the archosauromorph fossil record is comparatively abundant and ecologically diverse. Among early archosauromorphs, tanystropheids gained considerable attention due to the presence of extreme skeletal adaptations in response to sometimes overspecialized lifestyles. The origin and early radiation of Tanystropheidae, however, remains elusive. Here, a new Early Triassic archosauromorph is described and phylogenetically recovered as the sister-taxon of Tanystropheidae. ...
Tópico(s): Evolution and Paleontology Studies
2020 - Public Library of Science | PLoS ONE
Produção Nacional
Revisado por pares
Micheli Stefanello, Leonardo Kerber, Agustín G. Martinelli, Sérgio Dias‐da‐Silva,
Probainognathian cynodonts are well represented in the fossil record from the Middle and Upper Triassic of South America, especially in Brazil and Argentina. In this contribution, we describe a new genus and species of non-mammaliaform prozostrodontian cynodont from southern Brazil. The new taxon comes from the Niemeyer Site, a locality in which the traversodontid cynodont Siriusgnathus niemeyerorum is numerically dominant, whereas probainognathians and other tetrapods are comparatively scarce. ...
Tópico(s): Ichthyology and Marine Biology
2020 - Taylor & Francis | Journal of Vertebrate Paleontology
Produção Nacional
Revisado por pares
Juliana Hipólito, Bruna dos Santos Bandeira Sousa, Rafael Cabral Borges, Rafael Melo de Brito, Rodolfo Jaffé, Sérgio Dias, Vera Lúcia Imperatriz-Fonseca, Tereza Cristina Giannini,
The assessment of nature's contribution to people (NCP) is an important strategy for decision-making given the increasing need to reconcile biodiversity and human society with conservation. A monetary and a non-monetary approaches were combined to evaluate the pollination services provided by two Brazilian protected areas (PAs) in northern (Serra da Bocaina, Pará) and southeastern region (Mata do Jambreiro, Minas Gerais) within the Amazon forest and Atlantic forest biomes, respectively. The monetary ...
Tópico(s): Economic and Environmental Valuation
2019 - Elsevier BV | Global Ecology and Conservation
Produção Nacional
Revisado por pares
Carlos Augusto Metidieri Menegozzo, Frederico Teixeira-Júnior, Sérgio Dias do Couto Netto, Octacílio Martins-Júnior, Celso de Oliveira Bernini, Edivaldo Massazo Utiyama,
Colorectal cancer is one of the most frequent types of malignant neoplasms. Age is a risk factor for this disease, with 75% of cases diagnosed in patients older than 65 years. Complications such as obstruction, hemorrhage, and perforation are present in more than one-third of cases and require emergency treatment. We aim to analyze the profile of elderly patients undergoing surgery for complicated colorectal cancer, and to evaluate factors related to worse short-term prognosis.A retrospective analysis ...
Tópico(s): Colorectal and Anal Carcinomas
2019 - Elsevier BV | Clinics
Produção Nacional
Revisado por pares
Lívia Roese‐Miron, Ane Elise Branco Pavanatto, Flávio Augusto Pretto, Rodrigo Temp Müller, Sérgio Dias‐da‐Silva, Leonardo Kerber,
Traversodontidae is a less inclusive clade of cynognathian cynodonts that lived during the Triassic. Recently, a traversodontid from the southern Brazilian Triassic beds was described – Siriusgnathus niemeyerorum – based upon specimens found exclusively in its type-locality. No absolute age or index fossils have been reported for this locality, which prevents an accurate biostratigraphic correlation. In the present contribution, we describe the first specimens of S. niemeyerorum found outside its type- ...
Tópico(s): Evolution and Paleontology Studies
2019 - Elsevier BV | Journal of South American Earth Sciences
Produção Nacional
Revisado por pares
Cristián Pacheco, Rodrigo Temp Müller, Max C. Langer, Flávio Augusto Pretto, Leonardo Kerber, Sérgio Dias‐da‐Silva,
Predatory dinosaurs were an important ecological component of terrestrial Mesozoic ecosystems. Though theropod dinosaurs carried this role during the Jurassic and Cretaceous Periods (and probably the post-Carnian portion of the Triassic), it is difficult to depict the Carnian scenario, due to the scarcity of fossils. Until now, knowledge on the earliest predatory dinosaurs mostly relies on herrerasaurids recorded in Carnian strata of South America. Phylogenetic investigations recovered the clade ...
Tópico(s): Evolution and Paleontology Studies
2019 - PeerJ, Inc. | PeerJ
Carla P. Gomes, Sandrina Nóbrega‐Pereira, Beatriz Domingues-Silva, Kenny Rebelo, Catarina Alves-Vale, Sérgio Marinho, Tânia Carvalho, Sérgio Dias, Bruno Bernardes de Jesus,
Long non-coding RNAs (lncRNAs) represent a substantial portion of the human transcriptome. LncRNAs present a very stringent cell-type/tissue specificity being potential candidates for therapeutical applications during aging and disease. As example, targeting of MALAT1, a highly conserved lncRNA originally identified in metastatic non-small cell lung cancer, has shown promising results in cancer regression. Nevertheless, the regulation and specificity of MALAT1 have not been directly addressed. Interestingly, ...
Tópico(s): RNA Research and Splicing
2019 - BioMed Central | BMC Cancer
Produção Nacional
Revisado por pares
Maurício S. Garcia, Rodrigo Temp Müller, Átila Augusto Stock Da‐Rosa, Sérgio Dias‐da‐Silva,
Late Triassic deposits from south Pangea (Argentina and Brazil) bear the oldest (so far) and most informative unequivocal records of dinosaurs worldwide. Herein we describe a new lagerpetid dinosauromorph from a classic dinosaur-bearing locality (Cerro da Alemoa site) from the Candelária Sequence (Santa Maria Formation), southern Brazil, and report the oldest co-occurrence of dinosaurs, lagerpetids and silesaurids, in the same layer of a Triassic outcrop. Although tentatively regarded as a skeletally ...
Tópico(s): Evolution and Paleontology Studies
2019 - Elsevier BV | Journal of South American Earth Sciences
Produção Nacional
Revisado por pares
Thiago Fossile, Jéssica Ferreira, Dione da Rocha Bandeira, Sérgio Dias‐da‐Silva, André Carlo Colonese,
Sambaquis are archaeological shell mounds and middens formed by pre-Columbian populations inhabiting the Atlantic Forest coast of Brazil between the Middle and Late Holocene. Beyond their recognized cultural values, sambaquis are valuable biological archives for tracking changes in past biodiversity and informing modern conservation studies and management. In this contribution we reviewed the published record of faunal remains from archaeological sites located in Babitonga Bay, in the state of Santa ...
Tópico(s): Marine animal studies overview
2019 - Elsevier BV | Quaternary International
Produção Nacional
Revisado por pares
Maurício S. Garcia, Flávio Augusto Pretto, Sérgio Dias‐da‐Silva, Rodrigo Temp Müller,
Discoveries in Carnian-aged rocks are establishing a rich and diverse dinosaurian fauna at the so-called 'dawn of the age of dinosaurs' in the Late Triassic of Western Gondwana. Accordingly, Brazilian strata from the Candelária Sequence have contributed extensively to this trend. Here, we present a new dinosaurian specimen (CAPPA/UFSM 0200) from this geological unit. The material was collected at a fossiliferous site that had no previous record of dinosaurs. Our specimen comprises a single ilium, ...
Tópico(s): Amphibian and Reptile Biology
2019 - Brazilian Academy of Sciences | Anais da Academia Brasileira de Ciências
Produção Nacional
Revisado por pares
Maurício S. Garcia, Rodrigo Temp Müller, Sérgio Dias‐da‐Silva,
The controversial dinosauriform Teyuwasu barberenai Kischlat, 1999 (Fig. 1B) is based on a right femur (BSPG AS XXV 53) and tibia (BSPG AS XXV 54), formerly referred to the pseudosuchian 'Hoplitosuchus raui' (= Hoplitosaurus raui) Huene, 1938 (see also Huene, 1942). This material comes from a classic Late Triassic (Carnian) locality in southern Brazil (Fig. 1A), the Cerro da Alemoa outcrop on the Alemoa complex, that has yielded several noteworthy tetrapod specimens (see Garcia et al., 2019, for a complete ...
Tópico(s): Evolution and Paleontology Studies
2019 - Q15088586 | Zootaxa
Produção Nacional
Revisado por pares
Thiago Fossile, Jéssica Ferreira, Dione da Rocha Bandeira, Levy Figuti, Sérgio Dias‐da‐Silva, Niklas Hausmann, Harry K. Robson, David Orton, André Carlo Colonese,
Abstract Small‐scale fisheries provide food and livelihoods for thousands of people along the Brazilian coastline. However, considerable uncertainties still surround the extent to which artisanal and subsistence fisheries contribute to the total of national landings and their historical ecological significance. Fisheries monitoring is deficient in Brazil, and historical records are limited to irregular accounts spanning the last few decades, while this coastline has supported human populations for ...
Tópico(s): Marine animal studies overview
2019 - Wiley | Fish and Fisheries
Produção Nacional
Revisado por pares
Ane Elise Branco Pavanatto, Leonardo Kerber, Sérgio Dias‐da‐Silva,
Abstract The brain endocasts of the late Triassic (Carnian) traversodontids (Eucynodontia: Gomphodontia) Siriusgnathus niemeyerorum and Exaeretodon riograndensis from southern Brazil are described based on virtual models generated using computed tomography scan data. Their skull anatomy resembles that of other non‐mammaliaform cynodonts, showing an endocranial cavity that is not fully ossified. A “V‐shaped” orbitosphenoid, neither fully developed nor ossified is present in E. riograndensis . The nasal ...
Tópico(s): Ichthyology and Marine Biology
2019 - Wiley | Journal of Morphology
Produção Nacional
Revisado por pares
Micheli Stefanello, Rodrigo Temp Müller, Leonardo Kerber, Ricardo N. Martínez, Sérgio Dias‐da‐Silva,
Ecteniniidae comprises an endemic radiation of carnivore probainognathian cynodonts from the Late Triassic of South America. Three taxa have been included in this clade: Ecteninion lunensis Martínez et al., 1996 and Diegocanis elegans Martínez et al., 2013 from Argentina, and Trucidocynodon riograndensis Oliveira et al., 2010 from Brazil. Herein, a new specimen (skull and mandible) assigned to T. riograndensis from the Carnian of the Candelária Sequence (Southern Brazil) is described. A phylogenetic ...
Tópico(s): Ichthyology and Marine Biology
2018 - Q15088586 | Zootaxa
Produção Nacional
Sérgio Dias da Costa Júnior, João Victor de Oliveira Santos, Luís André de Almeida Campos, Marcela Araújo Pereira, Nereide Stela Santos-Magalhães, Isabella Macário Ferro Cavalcanti,
The aim of this study was to determine the antibacterial and antibiofilm properties of quercetin against clinical isolates of Staphyloccocus aureus and Staphylococcus saprophyticus with resistance profile. The antibacterial activity of quercetin was performed by the determination of the minimum inhibitory concentration (MIC) through the microdilution method according to the Clinical and Laboratory Standards Institute (CLSI). The percentage of inhibition of Staphylococcus spp. biofilm, after treatment ...
Tópico(s): Oral microbiology and periodontitis research
2018 - Infogain Publication | International Journal of Environment Agriculture and Biotechnology
Produção Nacional
Revisado por pares
Rodrigo Temp Müller, Max C. Langer, Sérgio Dias‐da‐Silva,
Despite representing a key-taxon in dinosauromorph phylogeny, Lagerpertidae is one of the most obscure and enigmatic branches from the stem that leads to the dinosaurs. Recent new findings have greatly increased our knowledge about lagerpetids, but no phylogenetic analysis has so far included all known members of this group. Here, we present the most inclusive phylogenetic study so far conducted for Lagerpetidae. Phylogenetic analyses were performed based on three independent data matrixes. In two ...
Tópico(s): Paleontology and Evolutionary Biology
2018 - Q15088586 | Zootaxa
Produção Nacional
Revisado por pares
Rodrigo Temp Müller, Max C. Langer, Sérgio Dias‐da‐Silva,
The rise of sauropodomorphs is still poorly understood due to the scarcity of well-preserved fossils in early Norian rocks. Here, we present an association of complete and exceptionally well-preserved dinosaur skeletons that helps fill that gap. They represent a new species, which is recovered as a member of a clade solely composed of Gondwanan Triassic taxa. The new species allows the definition of a set of anatomical changes that shaped sauropodomorph evolution along a period from 233 to 225 Ma, ...
Tópico(s): Ichthyology and Marine Biology
2018 - Royal Society | Biology Letters
Produção Nacional
Revisado por pares
Ane Elise Branco Pavanatto, Flávio Augusto Pretto, Leonardo Kerber, Rodrigo Temp Müller, Átila Augusto Stock Da‐Rosa, Sérgio Dias‐da‐Silva,
A new Upper Triassic fossiliferous outcrop, the Niemeyer Site, from the Santa Maria Supersequence (Paraná Basin, Southern Brazil) is reported. The lithology found in this locality is consistent with that found in the Candelária Sequence. The high prevalence of traversodontid cynodonts in this site is particularly notable, with collected specimens mostly composed of isolated bones and fragmentary specimens, but also including well-preserved skulls and mandibles. Probainognathian cynodonts and archosauromorphs ...
Tópico(s): Fish biology, ecology, and behavior
2018 - Elsevier BV | Journal of South American Earth Sciences
Produção Nacional
Revisado por pares
Lúcio Roberto da Silva, Rodrigo Temp Müller, Marco Aurélio Gallo de França, Sérgio Furtado Cabreira, Sérgio Dias‐da‐Silva,
In the present contribution, we aim to present the osteology of ‘ULBRA-PVT-281’, which comprises the best-preserved skeleton of Prestosuchus chiniquensis ever found. ULBRA-PVT-281 combines the morphology of two classic specimens referred to P. chiniquensis, UFRGS-PV-0156-T and UFRGSPV- 0152-T, reunited in a single operational taxonomic unit (OTU) in previous phylogenetic studies. Therefore, the new specimen reinforces the combination of both specimens. We performed a phylogenetic analysis, combining ...
Tópico(s): Ichthyology and Marine Biology
2018 - Taylor & Francis | Historical Biology
Produção Nacional
Revisado por pares
Rodrigo Temp Müller, Max C. Langer, Mario Bronzati, Cristián Pacheco, Sérgio Furtado Cabreira, Sérgio Dias‐da‐Silva,
An exceptional new specimen (CAPPA/UFSM 0035) of Buriolestes schultzi was discovered during recent fieldwork at the type locality of the taxon, which is Carnian in age (Late Triassic). This early sauropodomorph is peculiar owing to its faunivorous feeding habits, unusual amongst the members of this large omnivorous/herbivorous clade. The specimen incorporates new data on skeletal portions that have so far been unknown for B. schultzi, particularly regarding the skull and axial skeleton. As such, B. ...
Tópico(s): Ichthyology and Marine Biology
2018 - Oxford University Press | Zoological Journal of the Linnean Society
Ana C. Gregório, Manuela Lacerda, Paulo Figueiredo, Sérgio Simões, Sérgio Dias, João Nuno Moreira,
A major challenge in the management of breast cancer disease has been the development of metastases. Finding new molecular targets and the design of targeted therapeutic approaches to improve the overall survival and quality of life of these patients is, therefore, of great importance. Nucleolin, which is overexpressed in cancer cells and tumor-associated blood vessels, have been implicated in various processes supporting tumorigenesis and angiogenesis. Additionally, its overexpression has been ...
Tópico(s): RNA Research and Splicing
2018 - Elsevier BV | Critical Reviews in Oncology/Hematology
Neidy V. Rodrigues, Daniel V. Correia, Sofia Mensurado, Sandrina Nóbrega‐Pereira, Ana deBarros, Fernanda Kyle‐Cezar, Andrew Tutt, Adrian Hayday, Haakan Norell, Bruno Silva‐Santos, Sérgio Dias,
Abstract Vγ9Vδ2 T cells, the main subset of γδ T lymphocytes in human peripheral blood, are endowed with antitumor functions such as cytotoxicity and IFNγ production. These functions are triggered upon T-cell receptor–dependent activation by non-peptidic prenyl pyrophosphates (“phosphoantigens”) that are selective agonists of Vγ9Vδ2 T cells, and which have been evaluated in clinical studies. Because phosphoantigens have shown interindividual variation in Vγ9Vδ2 T-cell activities, we asked whether ...
Tópico(s): Lipid metabolism and disorders
2018 - American Association for Cancer Research | Cancer Immunology Research
Produção Nacional
Revisado por pares
Rodrigo Temp Müller, Maurício S. Garcia, Átila Augusto Stock Da‐Rosa, Sérgio Dias‐da‐Silva,
Sedimentary compression can produce deep changes in the organismal morphology during fossil diagenesis, so that intrinsic biological aspects (e.g. internal architecture of bones) could also generate non-natural traits when determinate bone element suffers sedimentary compression. Here we report a particular taphonomic case, in which the mode of preservation of a basal sauropodomorph from the Late Triassic of Brazil offers a valuable opportunity to examine the effects of sedimentary compression on ...
Tópico(s): Paleontology and Stratigraphy of Fossils
2018 - Elsevier BV | Journal of South American Earth Sciences