Giuseppe Musumeci, Paola Castrogiovanni, Marta Anna Szychlinska, Rosa Imbesi, Carla Loreto, Sergio Castorina, Salvatore Giunta,
In our previous work we have shown that L-Tryptophan (TrP) enriched diet prevents the age-induced decline of hippocampal Serotonin (5-HT) production. Considering that loss or reduction in 5-HT neurotransmission may contribute to age-related cognitive decline, here we have investigated the effect of such diet on passive avoidance (PA) behavior, cell death, pro- and anti- apoptotic molecules (BAX, Bcl-2 and Caspase-3) and an important transcription factor involved in synaptic plasticity and memory (CREB). ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2016 - Elsevier BV | Brain Research Bulletin
Paola Castrogiovanni, Angelo Di Giunta, Claudia Guglielmino, Federico Roggio, Domenico M. Romeo, Federica Fidone, Rosa Imbesi, Carla Loreto, Sergio Castorina, Giuseppe Musumeci,
The aim of this study was to investigate the effects of kinesio taping (KT) in combination with moderate adapted exercise on the functional outcome of patients with knee osteoarthritis. We included 66 patients who presented pain and functional impairment with osteoarthritis. At the end of the treatment, only 57 patients remained because nine patients were excluded. Patients were randomly allocated to three treatment groups: (1) exercise group; (2) exercise KT with tension application (stabilizing effect) ...
Tópico(s): Foot and Ankle Surgery
2016 - Multidisciplinary Digital Publishing Institute | Journal of Functional Morphology and Kinesiology
Giuseppe Musumeci, Paola Castrogiovanni, Francesca M. Trovato, Rosa Imbesi, Salvatore Giunta, Marta Anna Szychlinska, Carla Loreto, Sergio Castorina, Ali Mobasheri,
Osteoarthritis ( OA ) is a common musculoskeletal disorder characterized by slow progression and joint tissue degeneration. Aging is one of the most prominent risk factors for the development and progression of OA . OA is not, however, an inevitable consequence of aging and age‐related changes in the joint can be distinguished from those that are the result of joint injury or inflammatory disease. The question that remains is whether OA can be prevented by undertaking regular physical activity. Would ...
Tópico(s): Lower Extremity Biomechanics and Pathologies
2014 - Wiley | Scandinavian Journal of Medicine and Science in Sports
Giuseppe Musumeci, Paola Castrogiovanni, Carla Loreto, Sergio Castorina, Karin Pichler, Annelie‐Martina Weinberg,
The epiphyseal plate is a hyaline cartilage plate that sits between the diaphysis and the epiphysis. The objective of this study was to determine the impact of an injury in the growth plate chondrocytes through the study of histological morphology, immunohistochemistry, histomorphometry and Western Blot analyses of the caspase-3 and cleaved PARP-1, and levels of the inflammatory cytokines, Interleukin-6 (IL-6) and Tumor Necrosis Factor alpha (TNF-α), in order to acquire more information about post- ...
Tópico(s): NF-κB Signaling Pathways
2013 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Produção Nacional
Revisado por pares
... artigo aborda a produção cinematográfica financiada pelo governo Sergio Loreto em Pernambuco (1922-1926). Por meio de textos ...
Tópico(s): Literature, Culture, and Criticism
2013 - FUNDAÇÃO GETÚLIO VARGAS | Estudos Históricos (Rio de Janeiro)
Venerando Rapisarda, Carla Loreto, Sergio Castorina, Gaetano Romano, Sebastiano Fabio Garozzo, Andrea Musumeci, Marcello Migliore, Roberto Avola, Diana Cinà, Cristoforo Pomara, Caterina Ledda,
An environmental contamination due to an asbestiform mineral fiber, fluoro-edenite (FE), caused a significantly increased mortality rate for malignant mesothelioma in Biancavilla, Italy. Exposure to fluoro-edenite has been associated with inflammatory processes as an early response to inhaled fibers. The aim was to explore prevalence of anti-nuclear autoantibodies (ANA) in a group of construction workers residing and working in the contaminated area. Prevalences for samples positive to ANA were 60% ( ...
Tópico(s): Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
2018 - Future Medicine | Future Oncology
Mario Tello, Gino Corsini, Luis Larrondo, Loreto Salas, Sergio Lobos, Rafael Vicuña,
Three new genes (Cs-mnp2A, Cs-mnp2B and Cs-mnp3) coding for manganese-dependent peroxidase (MnP) have been identified in the white-rot basidiomycete Ceriporiopsis subvermispora. The mature proteins contain 366 (MnP2A and MnP2B) and 364 (MnP3) amino acids, which are preceded by leader sequences of 21 and 24 amino acids, respectively. Cs-mnp2A and Cs-mnp2B appear to be alleles, since the corresponding protein sequences differ in only five residues. The upstream region of Cs-mnp2B contains a TATA box, ...
Tópico(s): Microbial Metabolism and Applications
2000 - Elsevier BV | Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression
Giuseppe Musumeci, Carla Loreto, Rosalia Leonardi, Sergio Castorina, Salvatore Giunta, Maria Luisa Carnazza, Francesca M. Trovato, Karin Pichler, Annelie‐Martina Weinberg,
Tópico(s): Bone Metabolism and Diseases
2012 - Springer Science+Business Media | Journal of Bone and Mineral Metabolism
Produção Nacional
Revisado por pares
Sita Luvangadio Lukoki Vunda, Ismael Pretto Sauter, Samuel Paulo Cibulski, Paulo Michel Roehe, Sérgio Augusto Loreto Bordignon, Marilise Brittes Rott, Miriam Anders Apel, Gilsane Lino von Poser,
Tópico(s): Essential Oils and Antimicrobial Activity
2012 - Springer Science+Business Media | Parasitology Research
Stefania Fioravanti, M. Antonietta Loreto, Lucio Pellacani, Sergio Raimondi, Paolo A. Tardella,
The reaction of mono- and disubstituted allylsilanes with (ethoxycarbonyl)nitrene allowed the preparation of the N-substituted allylamines 2a, 2b, 2e and 2d in yields up to 60%. The 2-ethoxyoxazolines 3a, 3b and 3c were isolated as minor products.
Tópico(s): Chemical Synthesis and Reactions
1993 - Elsevier BV | Tetrahedron Letters
Produção Nacional
Revisado por pares
Eduardo Luis Konrath, Marı́a Gabriela Ortega, Sérgio de Loreto Bordignon, Miriam Anders Apel, Amélia Teresinha Henriques, José Luis Cabrera,
The alkaloid extracts of four Huperzia and one Lycopodiella species, from Brazilian habitats, were tested for their in vitro anticholinesterase activities. IC(50) values showed a potent acetylcholinesterase inhibition for H. reflexa (0.11 ± 0.05 μg/mL), followed by H. quadrifariata (2.0 ± 0.3 μg/mL), H. acerosa (5.5 ± 0.9 μg/mL), H. heterocarpon (25.6 ± 2.7 μg/mL) and L. cernua (42.6 ± 1.5 μg/mL). A lower inhibition of butyrylcholinesterase was observed for all species with the exception of H. heterocarpon (8.3 ± ...
Tópico(s): Insect Pest Control Strategies
2011 - Taylor & Francis | Journal of Enzyme Inhibition and Medicinal Chemistry
Davide Fiore Bavaro, Michele Fabiano Mariani, Emma Diletta Stea, Loreto Gesualdo, Gioacchino Angarano, Sergio Carbonara,
Sphingomonas paucimobilis is an emerging aerobic, nonfermenting gram-negative, opportunistic bacterium involved in many healthcare-associated infections. We herein report the first outbreak of S paucimobilis catheter related bacteriemia occurred on the same day in 3 patients sharing a dialysis room. This report suggests that S paucimobilis could represent a further emerging cause of rapidly spreading healthcare-associated infections, and highlights the importance of a high level of surveillance ...
Tópico(s): Bacterial biofilms and quorum sensing
2020 - Elsevier BV | American Journal of Infection Control
Loreto Reyes, Jorge Rodríguez, Sergio Urzúa,
We analyze the economic returns to different postsecondary degrees in Chile. We posit a schooling decision model with unobserved ability, observed test scores and labor market outcomes. We benefit from administrative records to carry out our empirical strategy. Our results show positive average returns to postsecondary degrees, especially for five-year degrees. However, we also uncover a large fraction of individuals with realized negative net returns. Although psychic benefits of postsecondary ...
Tópico(s): Intergenerational and Educational Inequality Studies
2013 - RELX Group (Netherlands) | SSRN Electronic Journal
Marcelo Miranda, G. Kuester, Loreto Ríos, Esteban Basáez, Sergio Hazard,
In recent years there has been growing interest in the effect of music as alternative or add-on therapy in different neurological conditions [ [1] Sacks O. The power of music. Brain. 2006; 129: 2528-2532 Crossref PubMed Scopus (109) Google Scholar ]. However, there are only a few reports on its effects on epilepsy [ 2 Hughes J.R. Daaboul Y. Fino J.J. et al. The Mozart effect on epileptiform activity. Clin Electroencephalogr. 1998; 29: 109-119 Crossref PubMed Scopus (112) Google Scholar , 3 Hughes J.R. Fino ...
Tópico(s): EEG and Brain-Computer Interfaces
2010 - Elsevier BV | Epilepsy & Behavior
Produção Nacional
Revisado por pares
Adhemar Longatto‐Filho, Sónia Maria Miranda Pereira, Celso di Loreto, Maria Lúcia Utagawa, Sérgio Makabe, Marina Yoshiê Sakamoto Maeda, J Marqués, Carmen L.F. Santoro, Adauto Castelo,
Objective.To compare the performances of Papanicolaou test (PapTest) and of a new liquid-based cytology method, DNA-CitoliqR System (DCS), in a high-risk population, with histology confirmation.Methods.Paired specimens of exfoliated cervical cells were collected under split-sample protocol.All patients were submitted to colposcopy and a biopsy taken when any atypical transformation zone was seen.Sensitivity, specificity, positive and negative predictive values, and overall accuracy of both conventional ...
Tópico(s): Global Cancer Incidence and Screening
2005 - Elsevier BV | Gynecologic Oncology
Produção Nacional
Revisado por pares
Bianca Ott Andrade, Camila Leal Bonilha, Gerhard E. Overbeck, Eduardo Vélez‐Martin, Rosângela Gonçalves Rolim, Sérgio Augusto de Loreto Bordignon, Ângelo Alberto Schneider, Cleusa Vogel Ely, Dióber Borges Lucas, Élen Nunes Garcia, Emily D. dos Santos, Fábio Piccin Torchelsen, Mariana S. Vieira, Pedro Joel Silva da Silva Filho, Pedro Maria Abreu Ferreira, Rafael Trevisan, Raquel Hollas, Sérgio Campestrini, Valério D. Pillar, Ilsi Iob Boldrini,
Abstract Aims We offer a first classification of South Brazilian grasslands ( Campos Sulinos ) based on quantitative vegetation data and describing grassland types in terms of dominant and indicator species. Location South Brazilian grasslands (Paraná, Santa Catarina, Rio Grande do Sul states). Methods We described vegetation plots in 167 sampling units throughout the region using a stratified nested design, totalizing 1,502 1 m² quadrats. We classified vegetation using cluster analysis based on Bray– ...
Tópico(s): Plant and animal studies
2018 - Wiley | Applied Vegetation Science
Produção Nacional
Revisado por pares
Marí Castro Santos, Natally S.B. Toson, M.C.B. Pimentel, Sérgio Augusto de Loreto Bordignon, Andreas Sebastian Loureiro Mendez, Amélia T. Henriques,
Cuphea is the largest genus of the Lythraceae family. It is popularly known as "sete-sangrias" in Brazil used in folk medicine as a diuretic, antipyretic, anti-inflammatory, laxative and antihypertensive agent. The raw material of Cuphea has shown promising results in the production of fitotherapics, which are chemically characterized by quercetin core flavonoids. Present work aims to investigate the chemical composition of Cuphea calophylla, Cuphea carthagenensis, Cuphea glutinosa and Cuphea racemosa ...
Tópico(s): Essential Oils and Antimicrobial Activity
2020 - Elsevier BV | Journal of Ethnopharmacology
Produção Nacional
Revisado por pares
Simone Quintana de Oliveira, Jadel M. Kratz, Vítor Clasen Chaves, TATIANA R. GUIMARÃES, DANIELLE T.M. COSTA, SAPFO DIMITRAKOUDI, Argyro Vontzalidou, Sérgio Augusto de Loreto Bordignon, CESAR P. SIMIONATO, Mário Steindel, Flávio Henrique Reginatto, Cláudia Maria Oliveira Simões, Eloir Paulo Schenkel,
Aristolochia triangularis Cham., is one of the most frequently used medicinal plant in Southern Brazil. Preparations containing the leaves and/or stems are traditionally used as anti-inflammatory, diuretic, as well as antidote against snakebites. This study screened A. triangularis extracts, fractions and isolated compounds for different bioactivities. A weak antiproliferative activity against human lung cancer cell line (A549) was observed only for chloroform fraction obtained from stems (CFstems - ...
Tópico(s): Drug Transport and Resistance Mechanisms
2019 - Brazilian Academy of Sciences | Anais da Academia Brasileira de Ciências
Produção Nacional
Revisado por pares
Ana Julia Maciel, Caroline Pavin Lacerda, Letícia Jacobi Danielli, Sérgio Augusto de Loreto Bordignon, Alexandre Meneghello Fuentefría, Miriam Anders Apel,
Abstract The purpose of this work was to determine the chemical composition and evaluate the antichemotactic, antioxidant, and antifungal activities of the essential oil obtained from the species Cryptocarya aschersoniana Mez , Cinnamomum amoenum ( Ness & Mart .) Kosterm. , and Schinus terebinthifolia Raddi , as well as the combination of C. aschersoniana essential oil and terbinafine against isolates of dermatophytes. Allo‐aromadendrene, bicyclogermacrene, and germacrene B were identified as major compounds ...
Tópico(s): Plant Pathogens and Fungal Diseases
2019 - Wiley | Chemistry & Biodiversity
Produção Nacional
Revisado por pares
Letícia Jacobi Danielli, Bruna Pippi, Jonathaline Apollo Duarte, Ana Julia Maciel, William Lopes, Michel Mansur Machado, Luís Flávio Souza de Oliveira, Marilene Henning Vainstein, Mário Lettieri Teixeira, Sérgio Augusto de Loreto Bordignon, Alexandre Meneghello Fuentefría, Miriam Anders Apel,
The aim of this study was to evaluate the antifungal, antichemotactic and antioxidant activities of Schinus lentiscifolius essential oil, as well as its combined effect with terbinafine and ciclopirox, against dermatophytes.Essential oil was analysed by GC-MS. The antifungal activity and the mechanism of action were determined by broth microdilution, sorbitol and ergosterol assays, as well as scanning electron microscopy. The checkerboard method was used for evaluating the interactions with commercial ...
Tópico(s): Bee Products Chemical Analysis
2018 - Oxford University Press | Journal of Pharmacy and Pharmacology
Produção Nacional
Revisado por pares
Caroll Schneider Cezarotto, Ariane Dorneles, Fernanda Giesel Baldissera, Matheus Brasil da Silva, Melissa Medeiros Markoski, Luiz Carlos Rodrigues, Alessandra Peres, Tiago Fazolo, Sérgio Augusto de Loreto Bordignon, Miriam Anders Apel, Pedro Roosevelt Torres Romão, Gilsane Lino von Poser,
Several species of Salvia are used as medicinal plants around the world. Biological activities of isolated compounds have been described, being diterpenes frequently responsible for the effects.Isolation of diterpenes from Salvia uliginosa Benth. and evaluation of the antichemotactic and leishmanicidal activities of the isolated compounds.To isolate diterpenes from S. uliginosa and evaluate their antichemotactic and leishmanicidal activities in vitro.The exudate of S. uliginosa was obtained by rapidly ...
Tópico(s): Plant biochemistry and biosynthesis
2018 - Elsevier BV | Phytomedicine
Produção Nacional
Revisado por pares
Cleusa Vogel Ely, Sérgio Augusto de Loreto Bordignon, Rafael Trevisan, Ilsi Iob Boldrini,
Red Lists are legal instruments that guide decisions within the context of conservation. Such lists can indicate the most appropriate conservation actions, leading to choices of priority areas for conservation, or create alternatives to ensure the preservation of threatened species. However, if Red Lists are effective tools in the conservation of threatened species, then it is important that we have guaranteed the quality of taxonomic delimitation of these taxa. Here we discuss a case of taxonomic ...
Tópico(s): Plant and animal studies
2017 - Elsevier BV | Journal for Nature Conservation
Produção Nacional
Revisado por pares
Gilson R. P. Moreira, Rodrigo Petry Eltz, Ramoim B. Pase, Gabriela T. Silva, Sérgio Augusto de Loreto Bordignon, Wolfram Mey, Gislene L. Gonçalves,
Galls induced by the larval stage of cecidosids (Lepidoptera: Cecidosidae) are complex, multi-trophic systems, still poorly studied. They may be associated with other insect feeding guilds, including inquilines, kleptoparasites, cecidophages, parasitoids, and predators. By causing death of the gall inducer early in life and altering the gall phenotype, inquilines may lead to misidentification of the true gall inducers. Here, we describe through light and scanning electron microscopy Cecidonius pampeanus, ...
Tópico(s): Insect-Plant Interactions and Control
2017 - Pensoft Publishers | ZooKeys
Produção Nacional
Revisado por pares
Letícia Jacobi Danielli, Bruna Pippi, Krissie D. Soares, Jonathaline Apollo Duarte, Ana Julia Maciel, Michel Mansur Machado, Luís Flávio Souza de Oliveira, Sérgio Augusto de Loreto Bordignon, Alexandre Meneghello Fuentefría, Miriam Anders Apel,
Chemosentizing of pathogens using natural compounds has been shown to be a promising alternative, resulting in increased efficacy of classical antifungal therapy. This study determines the chemical composition and antifungal, antichemotactic and antioxidant activities of Nectandra Rol species. ex Rottb. essential oils species, and its interaction with commercial antifungals. The chemical composition of N. megapotamica and N. lanceolata essential oils was established by gas chromatography–mass spectrometry ( ...
Tópico(s): Phytochemistry and Biological Activities
2017 - Elsevier BV | Industrial Crops and Products
Produção Nacional
Jéssyka Arruda da Cunha, Cecília Á. Scheeren, Joseânia Salbego, Luciane Tourem Gressler, Laurício M. Madaloz, Guerino Bandeira, Adriane Erbice Bianchini, Carlos Garrido Pinheiro, Sérgio Augusto de Loreto Bordignon, Berta Maria Heinzmann, Bernardo Baldisserotto,
ABSTRACT This study evaluated anesthetic efficacy and possible effects of the essential oils (EOs) of Cunila galioides (EOC) and Origanum majorana (EOO) on ventilatory rate (VR) and ionoregulation in Rhamdia quelen. In the anesthesia assessments, 50, 100, 200 and 300 μL L-1 EOC and 50, 100, 200, 300, 400 and 500 μL L-1 EOO were tested, and time for induction to sedation and anesthesia stages, as well as recovery, were taken. A second trial employed lower concentrations of both EOs, 10, 25, 50 and 100 ...
Tópico(s): Aquaculture Nutrition and Growth
2017 - Sociedade Brasileira de Ictiologia | Neotropical Ichthyology
Produção Nacional
Revisado por pares
Luciana R. Tallini, Graziele P.R. Pedrazza, Sérgio Augusto de Loreto Bordignon, Ana Carolina Oliveira Costa, Martin Steppe, Alexandre Meneghello Fuentefría, José Ângelo Silveira Zuanazzi,
This study uses high performance liquid chromatography and capillary electrophoresis as analytical tools to evaluate flavonoids in hydrolyzed leaves extracts of Rubus erythrocladus Mart., Rosaceae, and Morus nigra L., Moraceae.For phytochemical analysis, the extracts were prepared by acid hydrolysis and ultrasonic bath and analyzed by high performance liquid chromatography using an ultraviolet detector and by capillary electrophoresis equipped with a diode-array detector.Quercetin and kaempferol ...
Tópico(s): Plant Gene Expression Analysis
2015 - Springer Science+Business Media | Revista Brasileira de Farmacognosia
Tomás Rau, Sergio Urzúa, Loreto Reyes,
This paper estimates the effect of early exposure to toxic waste on academic achievement. We analyze longitudinal information from individuals attending primary and secondary schools in Arica (northern Chile). Between 1984 and 1989, the city received more than 20,000 tons of toxic chemicals containing high concentrations of lead, arsenic, and mercury. We implement difference-in-differences and reduced-form models to document robust relationships between residential and school proximity to the polluted ...
Tópico(s): Air Quality and Health Impacts
2015 - University of Chicago Press | Journal of the Association of Environmental and Resource Economists
Jorge Rodríguez, Sergio Urzúa, Loreto Reyes,
We analyze the economic returns to post-secondary degrees in Chile. We posit a schooling decision model with unobserved ability, degree-specific tuition costs, and earnings. We use administrative records to carry out our empirical analysis. Our results show positive average returns to post-secondary education, especially for five-year degrees. However, we also uncover significant heterogeneity. We document how unobserved characteristics (ability) determine the economic benefits of first- and second- ...
Tópico(s): Economic Growth and Productivity
2015 - University of Wisconsin Press | The Journal of Human Resources
Produção Nacional
Revisado por pares
Caroline Rita Venturi, Letícia Jacobi Danielli, Fernanda Klein, Miriam Anders Apel, Jarbas Alves Montanha, Sérgio Augusto de Loreto Bordignon, Paulo Michel Roehe, Alexandre Meneghello Fuentefría, Amélia T. Henriques,
Context: Glechon spathulata Benth. and Glechon marifolia Benth. (Lamiaceae, Mentheae) are aromatic plants used in traditional medicine for the treatment of viral infections.
Tópico(s): Fern and Epiphyte Biology
2014 - Taylor & Francis | Pharmaceutical Biology
Produção Nacional
Revisado por pares
Letícia Jacobi Danielli, Monique dos Reis, Mariana Bianchini, Graziela S. Camargo, Sérgio Augusto de Loreto Bordignon, Irene Clemes Külkamp‐Guerreiro, Alexandre Meneghello Fuentefría, Miriam Anders Apel,
Volatile oils have important biological properties, like antifungal activity. Several studies have investigated the ability of nanoparticulate systems as carriers of these substances in order to stabilize and reduce their volatility and improve their effects. The aims of this study were to analyze the chemical composition of volatile oil of Stenachaenium megapotamicum and to evaluate the antifungal activity of the pure oil and its nanoemulsion. The volatile oil obtained by hydrodistillation was ...
Tópico(s): Fern and Epiphyte Biology
2013 - Elsevier BV | Industrial Crops and Products