Produção Nacional
Revisado por pares
André Luís Ribeiro Ribeiro, Tatiany Oliveira de Alencar Menezes, Sérgio de Melo Alves Júnior, Sílvio Augusto Fernandes de Menezes, Sílvia Helena Marques da Silva, Antônio Carlos Rosário Vallinoto,
ObjectiveTo identify the oral carriage of Candida spp in patients infected by human immunodeficiency virus (HIV) and the possible correlation with clinical characteristics.Study DesignMucosal swab samples collected from 246 patients who were infected by HIV, did not have oral candidiasis, and were being treated with highly active antiretroviral therapy were analyzed. Yeast colonies that developed were identified by using the VITEK 2 automated system.ResultsCandida yeasts were present in 41.87% of ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2015 - Elsevier BV | Oral Surgery Oral Medicine Oral Pathology and Oral Radiology
Produção Nacional
Revisado por pares
Walessa Brasil da Silva, André Luís Ribeiro Ribeiro, Sílvio Augusto Fernandes de Menezes, João de Jesus Viana Pinheiro, Sérgio de Melo Alves Júnior,
Tópico(s): Central Venous Catheters and Hemodialysis
2013 - Springer Science+Business Media | Oral and Maxillofacial Surgery
Produção Nacional
Revisado por pares
Deylane Menezes Teles e Oliveira, Mário Sérgio Coelho Marroquim, Rafael Melo Santos de Serpa Brandão, Luiz Cláudio Demes da Mata Sousa, Francisco das Chagas Alves Lima, Semíramis Jamil Hadad do Monte, Antonio Vanildo de Sousa Lima, Antônio Gilberto Borges Coelho, Jhonatan Matheus Sousa Costa, Ricardo Martins Ramos, Ester Miranda Pereira, Adalberto Socorro da Silva,
To improve the availability of three-dimensional (3D) structures of HLA molecules, we created the pHLA3D database. In its first version, we modeled and published 106 3D structures of HLA class I molecules from the HLA-A, HLA-B, and HLA-C loci. This paper presents an update of this database, providing more 127 3D structures of HLA class II molecules (41 DR, 42 DQ, and 44 DP), predicted via homology modeling with MODELLER and SWISS-MODEL. These new 3D structures of HLA class II molecules are now freely ...
Tópico(s): Immunotherapy and Immune Responses
2020 - Elsevier BV | Human Immunology
Produção Nacional
Revisado por pares
Ana Mercy S. Brito, Adriana M. Godin, Paulo Sérgio de Almeida Augusto, Raquel R. Menezes, Ivo S.F. Melo, Marcela G.M.B. Dutra, Sarah O.A.M. Costa, Franciele A. Goulart, Felipe F. Rodrigues, Marcela Í. Morais, Renes R. Machado, Márcio M. Coelho,
Leflunomide, an immunosuppressive drug approved for the treatment of patients with rheumatoid arthritis, exhibits many mechanisms which may affect the nociceptive processing. Therefore, the present study aimed to evaluate the effect induced by leflunomide on the mechanical allodynia in models of inflammatory and neuropathic pain in mice and investigate mechanisms mediating such effects. Per os (p.o.) administration of leflunomide (25, 50 or 100 mg/kg) inhibited the inflammatory edema and mechanical ...
Tópico(s): Peripheral Neuropathies and Disorders
2017 - Elsevier BV | European Journal of Pharmacology
Produção Nacional
Revisado por pares
Orlando Francisco Amodeo Bueno, Maria Gabriela Menezes Oliveira, Letícia L. Lobo, Paulo Rogério Morais, Fabiana Henriques Machado de Melo, Sérgio Tufik,
1. Male Wistar rats were submitted to paradoxical sleep deprivation for 96 hr by a modified multiple platform technique. 2. Training of step-through inhibitory avoidance was performed immediately after the last day of paradoxical sleep deprivation. Twenty-four hr after training the animals were submitted to the retention test. 3. In Experiment 1, pilocarpine (4 mg/Kg, i.p.) or atropine (4 mg/Kg, i.p.) were administered daily during the paradoxical sleep deprivation period. Pilocarpine, but not atropine, ...
Tópico(s): Sleep and Wakefulness Research
2000 - Elsevier BV | Progress in Neuro-Psychopharmacology and Biological Psychiatry
Produção Nacional
Revisado por pares
Marina Rolo Pinheiro da Rosa, André Luís Ribeiro Ribeiro, Sílvio Augusto Fernandes de Menezes, João de Jesus Viana Pinheiro, Sérgio de Melo Alves Júnior,
Neurofibroma is a benign neoplasm derived from peripheral nerves whose etiology is still unclear. It may present as a solitary lesion or be associated with other diseases such as neurofibromatosis type I and II syndrome. This paper aims to report an extremely rare case of a solitary giant neurofibroma of the mental nerve whose etiology was related to a local trauma. A 14-year-old female patient presented an extensive left facial mass with a size of 7 × 5 × 4 cm, located between the teeth 33 and 37 in ...
Tópico(s): Soft tissue tumor case studies
2013 - Lippincott Williams & Wilkins | Journal of Craniofacial Surgery
Produção Nacional
Revisado por pares
André Luís Ribeiro Ribeiro, Walessa B. Silva, Sílvio Augusto Fernandes de Menezes, Maria S.S. Kataoka, Sérgio de Melo Alves Júnior, João de Jesus Viana Pinheiro,
Vascular injuries are a constant risk in facial trauma, although bone and soft tissues of the face have provided some protection to the larger blood vessels. However, penetrating injuries usually do not have this type of protection and can damage significant vascular arteries. This article presents a case of a stab wound, which led to airway obstruction arising to a large sublingual hematoma due to lingual artery injury. A healthy 44-year-old man was stabbed in the submandibular region and admitted ...
Tópico(s): Ear and Head Tumors
2014 - Lippincott Williams & Wilkins | Journal of Craniofacial Surgery
Produção Nacional
Revisado por pares
Viviane Gorete Silveira Mouro, Ana Luíza Pereira Martins, Janaína Silva, Tatiana Prata Menezes, Marcos de Lucca Moreira Gomes, Juraci Alves de Oliveira, Fabiana Cristina Silveira Alves de Melo, Sérgio Luís Pinto da Matta,
The toxic effects of cadmium (Cd) on reproductive parameters are widely described in the literature. Experimental models often make use of the intraperitoneal route ( i.p. ), although human intoxication occurs preferentially by the oral route and can be continuous. However, little is known about the effect of Cd administration routes on the testicular structure. Thus, this study investigated the testicular impact of Cd exposure comparing both i.p. and oral routes, both single dose (SD), in addition to ...
Tópico(s): Toxic Organic Pollutants Impact
2019 - Hindawi Publishing Corporation | Oxidative Medicine and Cellular Longevity
Produção Nacional
Revisado por pares
Eunice Anita de Moura Fortes, Maíra Soares Ferraz, Dayseanny Oliveira Bezerra, Aírton Mendes Conde Júnior, Rosa Maria Cabral, Francisco das Chagas Araújo Sousa, Hatawa Melo de Almeida, Gérson Tavares Pessoa, Danilo José Ayres de Menezes, Sérgio Paulo Lima Guerra, Ivan Barbosa Machado Sampaio, Antônio Chaves de Assís Neto, Maria Acelina Martins de Carvalho,
The gestation period in agoutis can range from 104 to 120 days. Knowledge regarding the morphological characteristics of embryos and fetuses is important as a base for studies in reproduction biotechnology, such as in vitro fertilization, embryo transfer and helps in determining congenital anomalies during the development phase. Thus, given the importance and lack of information about agouti embryology, the objective of this study was to characterize the external morphology and define the biometry ...
Tópico(s): Fish Ecology and Management Studies
2013 - Elsevier BV | Animal Reproduction Science
Produção Nacional
Revisado por pares
Tatiane Medeiros Melo, Michael Bottlinger, Elke Schulz, Wilson Mozena Leandro, Sérgio Botelho de Oliveira, Adelmo Menezes de Aguiar Filho, Ali El‐Naggar, Nanthi Bolan, Hailong Wang, Yong Sik Ok, Jörg Rinklebe,
Hydrothermal carbonization is a promising approach of biosolids management and its utilization as a soil amendment. This study evaluated the physical and chemical properties of hydrothermally converted biosolids (Sewchar) and its effect as a potential soil amendment on the growth of rice, beans, and radish. The germination experiment was conducted in a greenhouse in a randomized design using five Sewchar doses (0, 10, 20, 40 and 60 Mg ha−1). The results showed that hydrothermal carbonization influences ...
Tópico(s): Wastewater Treatment and Reuse
2019 - Elsevier BV | Journal of Environmental Management
Produção Nacional
Sanni Moraes de Oliveira, Jonas Oliveira Menezes, Sérgio Vital da Silva, Maria Djair Dias, Maria das Graças Melo Fernandes, Maria de Oliveira Ferreira Filha,
Objetivo: relatar a experiência de um projeto de extensão universitária sobre rodas de Terapia Comunitária Integrativa em quilombos, que ofertou aos idosos dessa comunidade um espaço terapêutico de escuta e fala na partilha de sofrimentos e descobertas. Método: participaram 16 pessoas, com idade entre 60 e 80 anos no período de maio de 2013 a janeiro de 2014, no Conde, Paraíba. Resultados: as histórias de vida relatadas nas rodas desenvolvidas foram marcadas pelo tema da luta pela terra, acesso ...
Tópico(s): Psychology and Mental Health
2017 - UNIVERSIDADE FEDERAL DE SANTA MARIA | Revista de Enfermagem da UFSM
Produção Nacional
Revisado por pares
Annielle Regina da Fonsêca Fernandes, Carla Lauise Rodrigues Menezes Pimenta, Ivana Fernandes Vidal, Gabriela Capriogli Oliveira, Raissa Saran Sartori, Raizza Barros Araújo, Márcia Almeida de Melo, Hélio Langoni, Sérgio Santos de Azevêdo,
Abstract The aim of this survey was to determine the seropositivity and risk factors forLeishmania spp. and Trypanosoma cruzi in dogs in the State of Paraíba, Northeastern Brazil. A total of 1,043 dogs were tested, and the serological diagnoses of Chagas disease (CD) and canine visceral leishmaniasis (CVL) was performed by the indirect fluorescent antibody test (IFAT). Animals that tested seropositive for both diseases (by IFAT) were further subjected to ELISA. Of the 1,043 dogs 81 (7.8%; 95% CI = 6.1- ...
Tópico(s): Research on Leishmaniasis Studies
2016 - Colégio Brasileiro de Parasitologia Veterinaria | Revista Brasileira de Parasitologia Veterinária/Brazilian Journal of Veterinary Parasitology
Produção Nacional
Revisado por pares
Paulo Henrique Soares, Eduardo Sérgio da Silva, Klauber Menezes Penaforte, Renata Aparecida Nascimento Ribeiro, Marcella Oliveira Gama de Melo, Diogo Tavares Cardoso, Ingrid Morselli Santos, Raíssa Cotta Machado, Clara Lemos Carneiro Trindade, Anna Karolyna Rodrigues Cunha, Rafael Gonçalves Teixeira‐Neto, Saulo Nascimento de Melo, Vanessa Vilela de Aquino, Vinícius Silva Belo,
Responsible companion animal guardianship (RCAG) comprises a set of concepts involving activities, behavior and care that guardians must provide to ensure the welfare of their animals. When such principles are disregarded, the risk of animals developing zoonotic diseases, such as canine visceral leishmaniasis (CVL), increases. This disease is a public health problem in many urban settings in Brazil because dogs are the main reservoirs of Leishmania and are involved in the transmission of the parasites ...
Tópico(s): Dermatological diseases and infestations
2022 - BioMed Central | BMC Veterinary Research
Produção Nacional
Revisado por pares
José D. Silva, Demmya Haryssam Menezes Melo, José A.G. Costa, Diego Figueiredo da Costa, Raizza Barros Sousa Silva, Márcia Almeida de Melo, Sérgio Santos de Azevêdo, Clebert José Alves,
RESUMO: Nos assentamentos rurais há maiores concentrações de reservatórios e vetores da leishmaniose visceral canina (LVC) devido às transformações ambientais resultantes da ação antrópica pela ocupação do território, no entanto, não há estudos no Brasil acerca de informações epidemiológicas da LVC em assentamentos rurais. O objetivo do presente trabalho foi determinar a soroprevalência para Leishmania sp. em cães de assentamentos rurais, bem como identificar os fatores de risco associados a infecção. ...
Tópico(s): Leptospirosis research and findings
2017 - Colégio Brasileiro de Patologia Animal (CBPA) | Pesquisa Veterinária Brasileira
Produção Nacional
Revisado por pares
Fernanda Carolina Ribeiro Dias, Marcos de Lucca Moreira Gomes, Fabiana Cristina Silveira Alves de Melo, Tatiana Prata Menezes, Ana Luíza Pereira Martins, Marli do Carmo Cupertino, Wagner Campos Otoni, Sérgio Luís Pinto da Matta,
Roots of Pfaffia glomerata are used in traditional medicine as aphrodisiacs and sexual stimulants. The aim of this study was to evaluate the action of the hydroalcoholic extract from the roots of Pfaffia glomerata on the Leydig cells, cavernous bodies and other penile constituents, as well as on serum testosterone and 17β-estradiol levels of adult mice. Mature male Swiss mice were divided into 6 groups: control (water), sildenafil citrate, 3 groups receiving daily doses of P. glomerata extract (100, ...
Tópico(s): Endometriosis Research and Treatment
2020 - Elsevier BV | Journal of Ethnopharmacology
Produção Nacional
Revisado por pares
Sarah Carvalho Vasconcelos, Lauana Alves Régis, Antônio Carlos Pereira de Menezes Filho, Cristiane de Melo Cazal, Paulo Sérgio Pereira, Marcela Christofoli,
O gênero Ocimum da família Lamiaceae compreende um grupo de plantas bem conhecidas como Ocimum gratissimum L. (alfavaca) e Ocimum basilicum (manjericão). Estudos revelam que essas plantas apresentam atividade antimicrobiana, inseticida, antioxidante, antifúngica, analgésica e imunoestimulante. Neste contexto, o objetivo deste estudo foi analisar a composição química dos óleos essenciais de O. gratissimum e O. basilicum coletadas em diferentes horários e com diferentes tempos de extração, bem como, ...
Tópico(s): Coconut Research and Applications
2021 - Grupo de Pesquisa Metodologias em Ensino e Aprendizagem em Ciências | Research Society and Development
Produção Nacional
Revisado por pares
Saulo Nascimento de Melo, Rafael Gonçalves Teixeira‐Neto, Guilherme Loureiro Werneck, Cláudio J. Struchiner, Renata Aparecida Nascimento Ribeiro, Lorena R. Sousa, Marcella Oliveira Gama de Melo, Clóvis Gomes de Carvalho Júnior, Klauber Menezes Penaforte, Marianna Nascimento Manhani, Vanessa Vilela de Aquino, Eduardo Sérgio da Silva, Vinícius Silva Belo,
Free-roaming dogs affected by visceral leishmaniasis (VL) contribute to the geographical expansion of the disease and require special attention from health authorities. The objectives of the present study were to determine the prevalences of VL in a population of free-roaming dogs in an endemic region of Brazil, to establish the spatial distribution of infected dogs, and to examine the effectiveness of euthanasia of infected dogs in controlling the disease in this particular population. Dogs were ...
Tópico(s): Viral Infections and Vectors
2018 - Elsevier BV | Preventive Veterinary Medicine
Produção Nacional
Revisado por pares
José Ulisses de Souza Melo, Radamés Bezerra Melo, Jefferson Menezes Viana Santos, Manoel Messias Campos Júnior, Sérgio Botelho Guimarães, Paulo Roberto Leitão de Vasconcelos,
PURPOSE: To evaluate the effect of bioflavonoid ternatin (TRT) on rat liver regeneration and oxidative stress after 70% partial hepatectomy (PH). METHODS: Thirty six young male Wistar rats were randomly assigned to two groups of 18 animals each - control (G1) and experimental (G2) - and were submitted to PH under inhalatory diethylether anesthesia. G1 rats received daily intraperitoneal (ip) injections of saline (NaCl 0.9% solution) 0.1 mL/kg for 14 days; G2 animals received daily ip injections of TRT 0.1% ...
Tópico(s): Drug-Induced Hepatotoxicity and Protection
2013 - Sociedade Brasileira Para o Desenvolvimento da Pesquisa em Cirurgia | Acta Cirúrgica Brasileira
Produção Nacional
Revisado por pares
Deylane Menezes Teles e Oliveira, Rafael Melo Santos de Serpa Brandão, Luiz Cláudio Demes da Mata Sousa, Francisco das Chagas Alves Lima, Semíramis Jamil Hadad do Monte, Mário Sérgio Coelho Marroquim, Antonio Vanildo de Sousa Lima, Antônio Gilberto Borges Coelho, Jhonatan Matheus Sousa Costa, Ricardo Martins Ramos, Adalberto Socorro da Silva,
HLA epitope analysis emerged as a strategy to determine alloimmune risk in solid organ transplantation. However, it requires not only knowledge on HLA amino acids sequences, but also on HLA three-dimensional structures. Unfortunately, the number of structures available is still unsatisfactory. This work reports the modelling of 106 heterotrimeric (alpha chain + β2M + peptide) HLA class I molecules. The models were generated by homology modelling using Modeller, refined using GalaxyRefine server, heterodimerized ...
Tópico(s): Immunotherapy and Immune Responses
2019 - Elsevier BV | Human Immunology
Produção Nacional
Revisado por pares
Juliana Angélica Estevão de Oliveira, Luis Filipe Nakayama, Lucas Zago Ribeiro, Talita Virgínia Fernandes de Oliveira, Stefano Neto Jai Hyun Choi, Edgar Menezes Neto, Viviane Santos Cardoso, Sérgio Atala Dib, Gustavo Barreto Melo, Caio V. Regatieri, Fernando Korn Malerbi,
Abstract Aims This study aims to compare the performance of a handheld fundus camera (Eyer) and standard tabletop fundus cameras (Visucam 500, Visucam 540, and Canon CR-2) for diabetic retinopathy and diabetic macular edema screening. Methods This was a multicenter, cross-sectional study that included images from 327 individuals with diabetes. The participants underwent pharmacological mydriasis and fundus photography in two fields (macula and optic disk centered) with both strategies. All images were ...
Tópico(s): Retinal and Optic Conditions
2023 - Springer Science+Business Media | Acta Diabetologica
Produção Nacional
Revisado por pares
Paulo Mácio Porto de Melo, Paulo Abdo do Seixo Kadri, Jean G. de Oliveira, Ítalo Capraro Suriano, Sérgio Cavalheiro, Fernando Menezes Braga,
Clivus fractures are rare and severe entities, usually associated with vascular or cranial nerve lesions and frequently diagnosed postmortem. Cervical epidural haematomas can be traumatic or spontaneous, manifested in acute or chronic form, and are treated surgically in the majority of cases, although the conservative treatment also can be indicated to patients with incomplete and non-progressive deficits. The authors report the case of a female patient, 8 years old, victim of trampling in public ...
Tópico(s): Neurosurgical Procedures and Complications
2003 - Thieme Medical Publishers (Germany) | Arquivos de Neuro-Psiquiatria
Produção Nacional
Revisado por pares
Karolyny Martins Balbinot, Felippe José Almeida Loureiro, Giordanna Pereira Chemelo, Ricardo Alves Mesquita, Aline Maria Pereira Cruz Ramos, Rommel Thiago Jucá Ramos, Artur Silva, Sílvio Augusto Fernandes de Menezes, Maria Sueli da Silva Kataoka, Sérgio de Melo Alves Júnior, João de Jesus Viana Pinheiro,
Background Ameloblastoma (AME) is characterized by a locally invasive growth pattern. In an attempt to justify the aggressiveness of neoplasms, the investigation of the role of stem cells has gained prominence. The SOX-2, NANOG and OCT4 proteins are important stem cell biomarkers. Methodology To verify the expression of these proteins in tissue samples of AME, dentigerous cyst (DC) and dental follicle (DF), immunohistochemistry was performed and indirect immunofluorescence were performed on the human ...
Tópico(s): Cancer Research and Treatments
2023 - PeerJ, Inc. | PeerJ
Produção Nacional
Revisado por pares
Fabia Pigatti Silva, Renato T. Souza, José Guilherme Cecatti, Renato Passini, Ricardo Porto Tedesco, Giuliane Jesus Lajos, Marcelo Luís Nomura, Patrícia Moretti Rehder, Tábata Z. Dias, Paulo F. Oliveira, Cleide M. Silva, Maria Laura Costa, Rodolfo C. Pacagnella, Samira M. Haddad, Vilma Zotarelli, Lucio T. Gurgel, Nelson Lourenço Maia Filho, Jacinta P. Mathias, Sérgio Tadeu Martins Marba, Ruth Guinsburg, Francisco Eulógio Martinez, Silvana Maria Quintana, Patrícia P. S. Melli, Francisco Edson de Lucena Feitosa, George N. Chaves, Ana Maria Feitosa Porto, Isabela Coutinho, Antonio C. Barbosa Lima, Elias F. Melo, Débora F. Leite, Melânia Maria Ramos Amorim, Adriana Suely Oliveira Melo, Fabiana O. Melo, Marília G. Martins, Marinea V. Nunes, Cláudio Sérgio Medeiros Paiva, Moisés Diôgo de Lima, Djacyr Magna Cabral Freire, Edson Gomes Tristão, Dênis José Nascimento, Carlos A. S. Menezes, Marcelo de Amorim Aquino, Janete Vettorazzi, Cintia E. Senger, Augusta M. B. Assumpção, Marcela A. F. Guedes, Maria Elizabeth Lopes Moreira, Vera Therezinha Medeiros Borges, Eduardo de Souza, Ana Cristina Perez Zamarian, Fátima Aparecida Henrique Lotufo, Kaliane P. Uzilin, Elvira A. O. Zanette, Carla Betina Andreucci, Tenílson Amaral Oliveira, Laércio R. Oliveira, Marcos Antonio Nogueira Santos, Nelson Sass, Mirian R. F. Silveira, Pedro R. Coutinho, Luciana T. Siqueira,
Abstract The association of body mass index (BMI) and gestational weight gain (GWG) with preterm birth (PTB) remains controversial in the literature. To evaluate different maternal BMI and GWG categories, according to the initial BMI, in relation to different PTB subtypes and perinatal outcomes, we conducted a secondary analysis of a multicentre cross-sectional study, along with a nested case-control study including PTB from 20 centers in Brazil. Pre-pregnancy underweight was associated with a lower ...
Tópico(s): Pregnancy and preeclampsia studies
2019 - Nature Portfolio | Scientific Reports
Produção Nacional
Lucas Machado de Menezes, Eduardo Luís de Souza Cruz, José Thiers Carneiro, Maria Sueli da Silva Kataoka, Sérgio de Melo Alves Júnior, João de Jesus Viana Pinheiro,
Ameloblastoma is an odontogenic benign tumor of epithelial origin that is characterized by slow, aggressive growth and invasive features. This disease is predominant in the mandible, and in adults between 30 and 40 years of age. It rarely occurs in the maxilla; there are few reported cases in literature, with relative proportions of 1:8 and 1:14 or even 1:58 diagnosed maxilla/mandible ameloblastoma cases, according to published retrospective studies. The purpose of this study is to present and discuss ...
Tópico(s): Periodontal Regeneration and Treatments
2017 - Elsevier BV | Human Pathology Case Reports
Produção Nacional
Revisado por pares
Átila Duque Rossi, João Locke Ferreira de Araújo, Tailah Bernardo de Almeida, Marcelo Ribeiro‐Alves, Camila de Almeida Velozo, Jéssica Maciel de Almeida, Isabela de Carvalho Leitão, Sâmila Natiane Ferreira, Jéssica da Silva Oliveira, Hugo José Alves, Helena Toledo Scheid, Débora S. Faffe, Rafael Mello Galliez, Renata Eliane de Ávila, Gustavo Gomes Resende, Mauro Martins Teixeira, Alice Laschuk Herlinger, Aliny dos Santos Carvalho, André F. Santos, Anna Carla Pinto Castiñeiras, Bianca Isabelle Barreto Teixeira, Bianca Ortiz da Silva, Bruno Clarkson, Bruno Eduardo Dematté, Camila Nacif, Camille Victória Leal Correia de Silva, Carolina Moreira Voloch, Caroline Macedo Nascimento, Carolyne Lalucha Alves L. da Graça, Cássia Cristina Alves Gonçalves, Cíntia Policarpo, Diana Mariani, Ekaterini Simões Goudouri, Elaine Sobral da Costa, Elisângela Silva, Enrico Bruno Riscarolli, Érica Ramos dos Santos Nascimento, Fabio Hecht Castro Medeiros, Fábio L. Monteiro, Fernanda Leitão dos Santos, Fernando Luz de Castro, Filipe Romero Rebello Moreira, Francine Bittencourt Schiffler, Gabriela Bergiante Kraychete, Gabriele Silveira da Cunha, Gisely Novaes Borges da Cunha, Guilherme S. Lira, Gustavo Peixoto Duarte da Silva, Harrison James Westgarth, Helena D.’Anunciação de Oliveira, Helena Keito Toma, Huang Fang, Inês Corrêa Gonçalves, Ingrid Camelo da Silva, Isabela Labarba Carvalho de Almeida, Joissy Aprigio de Oliveira, Juliana Cazarin de Menezes, Juliana T.S. Fortuna, Karyne Ferreira Monteiro, Kíssyla Harley Della Pascôa França, Laura Zalcberg Renault, Lendel Correia da Costa, Leticia Averbug Correa, Liane de Jesus Ribeiro, Lídia Theodoro Boullosa, Liliane Cavalcante, Luana dos Santos Costa, Lucas Matos Millioni, Luciana Jesus da Costa, Luiza M. Higa, Marcela dos Santos Durães, Marcelo Amaral de Souza, Marcelo Calado de Paula Tôrres, Mariana Freire Campos, Mariana Quinto, Mariane Talon de Menezes, Marisa Souza Correia, Mateus Rodrigues de Queiroz, Matheus Augusto Calvano Cosentino, Mayla Gabryele Miranda de Melo, Mirela D’arc Ferreira da Costa, Pedro Paz, Raíssa Mirella dos Santos Cunha da Costa, Raquel Fernandes Coelho, Richard Araújo Maia, Rodrigo Brindeiro, Romina Carvalho Ferreira, Sérgio Machado Lisboa, Thamiris dos Santos Miranda, Victor Akira Ota, Victoria Cortes Bastos, Viviane Guimarães Gomes, Orlando da Costa Ferreira Júnior, Terezinha Marta Pereira Pinto Castiñeiras, Renan P. Souza, Amílcar Tanuri, Renato Santana Aguiar, Shana Priscila Coutinho Barroso, Cynthia Chester Cardoso,
Abstract ACE2 and TMPRSS2 are key players on SARS-CoV-2 entry into host cells. However, it is still unclear whether expression levels of these factors could reflect disease severity. Here, a case–control study was conducted with 213 SARS-CoV-2 positive individuals where cases were defined as COVID-19 patients with respiratory distress requiring oxygen support (N = 38) and controls were those with mild to moderate symptoms of the disease who did not need oxygen therapy along the entire clinical course ( ...
Tópico(s): Long-Term Effects of COVID-19
2021 - Nature Portfolio | Scientific Reports
Produção Nacional
Revisado por pares
Thássio Mesquita, Itamar Couto Guedes de Jesus, Jucilene F. dos Santos, Grace Kelly Melo de Almeida, Carla M. L. de Vasconcelos, Sílvia Guatimosim, Fabrício Nunes Macedo, Robervan Vidal dos Santos, José Evaldo Rodrigues de Menezes‐Filho, Rodrigo Miguel‐dos‐Santos, Paulo Tojal Dantas Matos, Sérgio Scalzo, Valter Joviniano Santana‐Filho, Ricardo Luiz Cavalcanti de Albuquerque Júnior, Rose Nely Pereira‐Filho, Sandra Lauton‐Santos,
Ginkgo biloba is the most popular phytotherapic agent used worldwide for treatment of several human disorders. However, the mechanisms involved in the protective actions of Ginkgo biloba on cardiovascular diseases remain poorly elucidated. Taking into account recent studies showing beneficial actions of cholinergic signaling in the heart and the cholinergic hypothesis of Ginkgo biloba-mediated neuroprotection, we aimed to investigate whether Ginkgo biloba extract (GBE) promotes cardioprotection via ...
Tópico(s): Neurological Disorders and Treatments
2017 - Frontiers Media | Frontiers in Pharmacology
Produção Nacional
Revisado por pares
Sérgio Melo, Lezilda Carvalho Torgan, Mariângela Menezes, Vera L. M. Huszar, José Dias Corrêa, Reinaldo L. Bozelii,
A new Synedropsis species is described from a coastal tropical lagoon in south-eastern Brazil. This species has a single chloroplast in both views of the valve, apical pore fields composed of three slits, and uniseriate striae. It is planktonic and was found in brackish water. Synedropsis roundii is the eighth Synedropsis species to be described and the first to be found in a tropical region. We studied the seasonal dynamics of S. roundii, which can form blooms in the coastal Imboassica Lagoon, ...
Tópico(s): Aquatic Ecosystems and Phytoplankton Dynamics
2003 - Taylor & Francis | Phycologia
Produção Nacional
Revisado por pares
Mariana Mara Buen, Eliana Amaral, Renato T. Souza, Renato Passini, Giuliane Jesus Lajos, Ricardo Porto Tedesco, Marcelo Luís Nomura, Tábata Z. Dias, Patrícia Moretti Rehder, Maria Helena de Sousa, José Guilherme Cecatti, Sérgio Tadeu Martins Marba, Jacinta P. Matias, Nelson Lourenço Maia Filho, Vera Therezinha Medeiros Borges, Laércio R. Oliveira, Tenílson Amaral Oliveira, Augusta M. B. Assumpção, Maria Elizabeth Lopes Moreira, Marcela A. F. Guedes, Cintia E. Senger, Janete Vettorazzi, Francisco Eulógio Martinez, Silvana Maria Quintana, Patrícia P. S. Melli, Antonio C. F. Barbosa Lima, Débora F. Leite, Elias F. Melo, Dênis José Nascimento, Edson Gomes Tristão, Luciana F. Siqueira, Pedro R. Coutinho, Ruth Guinsburg, Ana Cristina Perez Zamarian, Eduardo de Souza, Marília G. Martins, Marynea V. Nunes, Cláudio Sérgio Medeiros Paiva, Djacyr Magna Cabral Freire, Moisés Diôgo de Lima, Ana Maria Feitosa Porto, Isabela Cristina Coutinho de Albuquerque Neiva Coêlho, Adriana Suely Oliveira Melo, Fabiana O. Melo, Melânia Maria Ramos Amorim, Carlos A. S. Menezes, Marcelo de Amorim Aquino, Francisco Edson Lucena Feitosa, George N. Chaves, M.R.F. Silveira, Nelson Sass, Fátima Aparecida Henrique Lotufo, Kaliane P. Uzilin, Carla Betina Andreucci, Elvira A. O. Zanette,
Abstract Spontaneous preterm birth (sPTB) is a major pregnancy complication involving biological, social, behavioural and environmental mechanisms. Workload, shift and intensity may play a role in the occurrence of sPTB. This analysis is aimed addressing the effect of occupational activities on the risk for sPTB and the related outcomes. We conducted a secondary analysis of the EMIP study, a Brazilian multicentre cross-sectional study. For this analysis, we included 1,280 singleton sPTB and 1,136 ...
Tópico(s): Maternal and Perinatal Health Interventions
2020 - Nature Portfolio | Scientific Reports
Produção Nacional
Alexandre Santos Bruno, Renata Gomes Miranda e Castor, Bárbara Betônico Berg, Daniela Esteves Ferreira dos Reis Costa, André Luis Lima Monteiro, Sérgio Scalzo, Karla Caroline Marques de Oliveira, Fernanda Luiza Menezes Bello, Grazielle Cordeiro Aguiar, Marcos Barrouin Melo, Robson A.S. Santos, Daniella Bonaventura, Sílvia Guatimosim, Marina Gomes Miranda e Castor, Anderson J. Ferreira, Stêfany B. A. Cau,
The consumption of highly refined carbohydrates increases systemic inflammatory markers, but its potential to exert direct myocardial inflammation is uncertain. Herein, we addressed the impact of a high-refined carbohydrate (HC) diet on mice heart and local inflammation over time. BALB/c mice were fed with a standard chow (control) or an isocaloric HC diet for 2, 4, or 8 weeks (HC groups), in which the morphometry of heart sections and contractile analyses by invasive catheterization and Langendorff- ...
Tópico(s): Protein Tyrosine Phosphatases
2023 - Elsevier BV | Cytokine
Produção Nacional
José Dêvede da Silva, Demmya Haryssam Menezes Melo, Érico Luiz de Barros Correia, José Romero Alexandre Alves, Diego Figueiredo da Costa, Severino Silvano dos Santos Higino, Sérgio Santos de Azevêdo, Clebert José Alves,
Rural settlements are defined as family-run agrarian spaces. Their purpose, based on public policies, is to strengthen family agriculture. They are peculiar environments that can predispose to the risk of diseases, especially zoonotic diseases, due to close natural contact with animals that can be sources of infection. The aim of this study was to determine the frequency of anti-Leptospira antibodies in dogs from rural settlements in the state of Paraíba, Northeast Brazil, and to identify the risk ...
Tópico(s): Leptospirosis research and findings
2017 - UNIVERSIDADE ESTADUAL DE LONDRINA | Semina Ciências Agrárias