Allan J. Baker, Sérgio L. Pereira, Tara Paton,
... PubMed Search for more papers by this author , Sérgio L Pereira Sérgio L Pereira Google Scholar Find this author on PubMed Search ... Baker Google Scholar Find this author on PubMed , Sérgio L Pereira Sérgio L Pereira Google Scholar Find this author on PubMed and ... 10.1098/rsbl.2006.0606 Allan J Baker, Sérgio L Pereira and Tara A Paton volume 3issue 2Biology Letters06 ...
Tópico(s): Coronary Artery Anomalies
2008 - Royal Society | Biology Letters
Produção Nacional
Revisado por pares
... rural development; territorial development; agricultural policies; ruralities.LEITE, Sergio Pereira. Ruralidades, enfoque territorial e políticas públicas diferenciadas para ...
Tópico(s): Rural and Ethnic Education
2020 - SciELO | Estudos Sociedade e Agricultura
Andreimar M. Soares, Ana Helena Januário, Miriam Vergínia Lourenço, Ana Maria Soares Pereira, Paulo Sérgio Pereira,
Medicinal plants constitute a very rich source of natural inhibitors of animal toxins, and may be used: 1) to study the mechanism of action of toxins and inhibitors; 2) to treat ophidian envenomation as a supplementary and/or alternative therapy; and 3) as models to design new drugs of interest in clinical medicine. Several Brazilian plants have been utilized in folk medicine as antiophidians. However, only a few species have been scientifically investigated and still fewer have had their active ...
Tópico(s): Phytochemistry and Bioactivity Studies
2004 - Thomson Reuters | Drugs of the Future
Produção Nacional
Revisado por pares
Camila Carla Guimarães, Denise Dias Oliveira, Mayara Valdevite, Ana Saltoratto, Sarazete Izidia Vaz Pereira, Suzelei de Castro França, Ana Maria Soares Pereira, Paulo Sérgio Pereira,
The Aβ peptide-mediated toxicity participates in the neuronal death that occurs in Alzheimer's disease. The present study aims to isolate the major compounds of Serjania erecta Radlk leaves and assess whether these compounds protect PC12 cells from Aβ25-35 peptide-induced toxicity. We isolated three flavonoid glycosides with high purity: quercetrin, vitexin, and isovitexin. The Aβ25-35 peptide alone decreased the PC12 cell viability in a concentration-dependent manner, as evaluated by the 3-(4,5- ...
Tópico(s): Alzheimer's disease research and treatments
2015 - Elsevier BV | Food and Chemical Toxicology
Produção Nacional
Revisado por pares
Heitor Ricardo Cosiski Marana, Jurandyr Moreira de Andrade, Ângelo do Carmo da Silva Mathes, Geraldo Duarte, Sérgio Pereira da Cunha, Sérgio Bighetti,
Background. Carcinoma of the cervix is the most common malignant tumor associated with pregnancy. The initial stages and premalignant lesions apparently present the same prognosis in pregnant and nonpregnant women; however, there are limited data regarding outcome for locally advanced cervical cancer in pregnancy. Case. A 26-year-old woman, gravida 4, para 3, at 14 weeks and 4 days' gestation, was diagnosed with a FIGO stage IIB squamous cell carcinoma of the cervix, treated by primary chemotherapy ...
Tópico(s): Family Support in Illness
2001 - Elsevier BV | Gynecologic Oncology
Produção Nacional
Revisado por pares
Ronaldo Biondo, Ana Maria Soares Pereira, Silvana Marcussi, Paulo Sérgio Pereira, Suzelei de Castro França, Andreimar M. Soares,
Phospholipases A2 (PLA2) are multifunctional proteins which exhibit varied biological activities correlated to the structural diversities of the sub-classes. The crude aqueous extract from subterranean system of Mandevilla velutina, a plant found in Brazilian savanna, was assayed for its ability to inhibit biological activities of several snake venoms and isolated PLA2s. The extract induced total inhibition of the phospholipase activity of Crotalus durissus terrificus venom and only partial inhibition ...
Tópico(s): Bioactive Natural Diterpenoids Research
2003 - Elsevier BV | Biochimie
Produção Nacional
Revisado por pares
Éric Sabourin, Cátia Grisa, Paulo André Niederle, Sérgio Pereira Leite, Carolina Milhorance, Angela Damasceno Ferreira, Sérgio Sauer, José Milton Andriguetto-Filho,
L’article traite des modalités du démantèlement récent des politiques publiques rurales et environnementales avec un recul de quelques années, en mobilisant l’examen de plusieurs volets : le foncier, l’agriculture familiale, le développement territorial rural, l’agroécologie et l’environnement. L’analyse porte sur les trois derniers gouvernements (Rousseff, Temer et Bolsonaro), à partir de l’approche du démantèlement de politiques publiques de Bauer et al. (Bauer MW, Jordan A, Green-Pedersen C, Heritier ...
Tópico(s): Agricultural and Food Sciences
2020 - Université des Réseaux d'Expression Française | Cahiers Agricultures
Produção Nacional
Revisado por pares
Ana Maria Soares Pereira, Camila Hernandes, Sarazete Izidia Vaz Pereira, Bianca Waléria Bertoni, Suzelei de Castro França, Paulo Sérgio Pereira, Sílvia Helena Taleb Contini,
Tópico(s): Seaweed-derived Bioactive Compounds
2014 - Elsevier BV | Chemico-Biological Interactions
Produção Nacional
Revisado por pares
Sarazete Izidia Vaz Pereira, Sílvia Helena Taleb Contini, Juliana da Silva Coppede, Paulo Sérgio Pereira, Bianca Waléria Bertoni, Suzelei de Castro França, Ana Maria Soares Pereira,
Croton antisyphiliticus is a medicinal plant widely used in the treatment of microbial infections, especially those affecting the genital tract. Crude extract, fractions and pure compound isolated from roots of this species were investigated to validate their antimicrobial activity against Escherichia coli and Staphylococcus aureus. The compound ent-kaur-16-en-18-oic acid was isolated as a major component (0.7% of crude extract), and its MIC value determined against S. aureus (ATCC 6538) was 250 μg/ ...
Tópico(s): Insect Pest Control Strategies
2012 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
Walace Fraga Rizo, Luís Eduardo Ferreira, Vanessa Colnaghi, Juliana Simões Martins, Leonardo Pereira Franchi, Catarina Satie Takahashi, Renê Oliveira Beleboni, Mozart Marins, Paulo Sérgio Pereira, Ana Lúcia Fachin,
Cancer has become a major public health problem worldwide and the number of deaths due to this disease is increasing almost exponentially. In the constant search for new treatments, natural products of plant origin have provided a variety of new compounds to be explored as antitumor agents. Tabernaemontana catharinensis is a medicinal plant that produces alkaloids with expressive antitumor activity, such as heyneanine, coronaridine and voacangine. The aim of present study was firstly to screen the ...
Tópico(s): Cancer therapeutics and mechanisms
2013 - Brazilian Society of Genetics | Genetics and Molecular Biology
Produção Nacional
Francinete Ramos Campos, Ana Helena Januário, Lisandra Vieira Rosas, Samara K.R. Nascimento, Paulo Sérgio Pereira, Suzelei de Castro França, Milade S.C. Cordeiro, Míriam Paula Alonso Toldo, Sérgio de Albuquerque,
Tópico(s): Plant biochemistry and biosynthesis
2004 - Elsevier BV | Fitoterapia
Produção Nacional
Revisado por pares
Fernanda Neves Estrela, Abraão Tiago Batista Guimarães, Amanda Pereira da Costa Araújo, Fabiano Guimarães Silva, Thiarlen Marinho da Luz, Abner Marcelino Silva, Paulo Sérgio Pereira, Guilherme Malafaia,
The toxicity of zinc oxide (ZnO NPs) and polystyrene nanoplastics (PS NaPs) has been tested in different animal models; however, knowledge about their impact on mice remains incipient. The aim of the current study is to evaluate the effects of these nanomaterials on Swiss mice after their individual exposure to a binary combination of them. The goal was to investigate whether short exposure (three days) to an environmentally relevant dose (14.6 ng/kg, i.p.) of these pollutants would have neurotoxic, ...
Tópico(s): Effects and risks of endocrine disrupting chemicals
2020 - Elsevier BV | Chemosphere
Produção Nacional
Revisado por pares
Éder Pereira Miguel, Alba Valéria Rezende, Fabrício Assis Leal, Eraldo Aparecido Trondoli Matricardi, Ailton Teixeira do Vale, Reginaldo Sérgio Pereira,
Resumo:O objetivo deste trabalho foi avaliar a eficácia da aplicação de modelos de análise de regressão e redes neurais artificiais (RNAs) na predição do volume de madeira e da biomassa acima do solo, da vegetação arbórea em área de cerradão. Volume de madeira e biomassa foram estimados com equações alométricas desenvolvidas para a área de estudo. Os índices de vegetação, como variáveis preditoras, foram estimados a partir de imagens do sensor LISS-III, e a área basal foi determinada por medições ...
Tópico(s): Remote Sensing and LiDAR Applications
2015 - Embrapa Informação Tecnológica | Pesquisa Agropecuária Brasileira
Sérgio Pereira Leite, V. Sundararajan,
Tópico(s): Global Financial Crisis and Policies
1990 - Springer Nature | Staff Papers
Eduardo Cunha de Souza, Alex E. Jalkh, Clement L. Trempe, Sérgio Pereira da Cunha, Charles L. Schepens,
Three young, otherwise healthy patients had a similar picture of unilateral central chorioretinitis associated with severe visual loss. Fluorescein angiography disclosed diffuse leakage under the neurosensory retina in the posterior pole, associated with multifocal areas of staining along the retinal vessels. Systemic examination showed a positive fluorescent treponemal antibody absorption test and a sharp increase in VDRL titers, indicative of active secondary syphilis. The patients responded dramatically ...
Tópico(s): Retinal and Optic Conditions
1988 - Elsevier BV | American Journal of Ophthalmology
Produção Nacional
Revisado por pares
Luciana de Barros Duarte, Elaine Christine Dantas Moisés, Ricardo de Carvalho Cavalli, Vera Lúcia Lanchote, Geraldo Duarte, Sérgio Pereira da Cunha,
Tópico(s): Pregnancy and Medication Impact
2009 - Springer Science+Business Media | European Journal of Clinical Pharmacology
Produção Nacional
Revisado por pares
Liege Slomp, Paulo Sérgio Pereira, Suzelei de Castro França, Sônia Marli Zingaretti, Renê Oliveira Beleboni,
Synthetic nematicides have been used broadly in past decades for the control of plant parasitic nematodes. Despite their relevant effectiveness, these compounds can cause great damage to the environment, and have a relevant impact on human and animal health. The growing search for new nematicides, particularly natural ones, may lead to higher safety and efficiency in nematode control. In this work, the in vitro nematocidal effect of ethanol extracts obtained from the following plant species was ...
Tópico(s): Helminth infection and control
2009 - Taylor & Francis | Pharmaceutical Biology
Produção Nacional
Revisado por pares
Antonio Cardoso Neto, Joaquim Coutinho Netto, Paulo Sérgio Pereira, Ana Maria Soares Pereira, Sílvia Helena Taleb Contini, Suzelei de Castro França, Márcia Ortiz Mayo Marques, Renê Oliveira Beleboni,
Abstract Objectives The purpose of the present work was to characterize the pharmacological profile of different L. alba chemotypes and to correlate the obtained data to the presence of chemical constituents detected by phytochemical analysis. Methods Essential oils from each L. alba chemotype (LP1—LP7) were characterized by gas chromatography–mass spectrometry (GC-MS) and extracted non-volatile compounds were analysed by HPLC and GC-MS. The anticonvulsant actions of the extracted compounds were studied ...
Tópico(s): Medicinal Plants and Neuroprotection
2009 - Oxford University Press | Journal of Pharmacy and Pharmacology
Produção Nacional
Revisado por pares
Cristiane Alves de Carvalho, Miriam Vergínia Lourenço, Bianca Waléria Bertoni, Suzelei de Castro França, Paulo Sérgio Pereira, Ana Lúcia Fachin, Ana Maria Soares Pereira,
Muitas doenças e processos degenerativos estão associados à superprodução de espécies reativas de oxigênio (ERO) o que tem estimulado vários grupos de pesquisa a investigarem o potencial antioxidante de substâncias produzidas por diversas famílias da flora mundial. O presente trabalho teve como objetivo avaliar a atividade antioxidante de extrato bruto hidroalcoólico de folhas de Jacaranda decurrrens e de frações obtidas a partir desse extrato, pelo método espectrométrico de descoloração do radical ...
Tópico(s): Phytochemicals and Antioxidant Activities
2009 - Springer Science+Business Media | Revista Brasileira de Farmacognosia
Produção Nacional
Revisado por pares
Rodrigo de Freitas Gomes, Antonio Cardoso Neto, V.L. Melo, Vanessa C. Fernandes, G. Dagrava, W.S. Santos, Paulo Sérgio Pereira, Lucélio Bernardes Couto, Renê Oliveira Beleboni,
In this work we describe the analgesic, anti-inflammatory and toxic activities as well as the phytochemical profile of the ethanol extract from Tabernaemontana catharinensis A. DC. (Apocynaceae) stem bark. Analgesic evaluation was carried out against chemical and thermal stimuli. Anti-inflammatory activity was investigated on carrageenan-induced edema in rats and toxicological studies (LD50) were conducted in mice. Phytochemical analyses were performed by standardized methodology. In an analgesic ...
Tópico(s): Pharmacological Effects of Natural Compounds
2009 - Taylor & Francis | Pharmaceutical Biology
Produção Nacional
Revisado por pares
Luciana C. Diogo, Renata S. Fernandes, Silvana Marcussi, Danilo L. Menaldo, Patrícia G. Roberto, Paula V. F. Matrangulo, Paulo Sérgio Pereira, Suzelei de Castro França, Silvana Giuliatti, Andreimar M. Soares, Miriam Vergínia Lourenço,
Abstract: We genetically modified Eclipta alba using Agrobacterium rhizogenes LBA 9402, with the aim of producing secondary metabolites with pharmacological properties against phospholipase A 2 and the myotoxic activities of snake venom. Extracts from in natura aerial parts and roots, both native and genetically modified ( in vitro ), were prepared and analysed by high‐performance liquid chromatography. In natura materials showed the coumestan wedelolactone at higher concentration in the aerial parts, ...
Tópico(s): Medicinal Plants and Neuroprotection
2009 - Wiley | Basic & Clinical Pharmacology & Toxicology
Produção Nacional
Revisado por pares
Geraldo Duarte, Alessandra Cristina Marcolin, Carla Vitola Gonçalves, Silvana Maria Quintana, Aderson Tadeu Berezowski, Antônio Alberto Nogueira, Sérgio Pereira da Cunha,
Objetivos: avaliar os aspectos diagnósticos, terapêuticos e as complicações dos casos de infecção do trato urinário (ITU) sintomática durante a gestação, que necessitaram de internação hospitalar. Métodos: foram incluídas 136 grávidas com diagnóstico clínico de pielonefrite. Foram avaliados: a idade e paridade da paciente, idade gestacional em que foi feito o diagnóstico, antecedentes de importância epidemiológica, propedêutica laboratorial para avaliação da infecção urinária, tratamento e evolução ...
Tópico(s): Ureteral procedures and complications
2002 - Thieme Medical Publishers (Germany) | Revista Brasileira Ginecologia e Obstetrícia
Produção Nacional
Revisado por pares
Sérgio Pereira da Cunha, João Ricardo Carreira Alves, M. Moura Lima, Jair Rosa Duarte, Luiz CV de Barros, José L da Silva, Angelo T Gammaro, Orlando de S Monteiro Filho, Amauri R Wanzeler,
Relata-se a freqüência de vegetais Bromeliaceae e de outros criadouros com plantas positivos para Aedes aegypti durante dois ciclos operacionais (tratamento focal) consecutivos no Município do Rio de Janeiro, RJ, cujos períodos foram de 12 de novembro de 2000 a 9 de março de 2001 e 12 de março de 2001 a 15 de junho de 2001. O trabalho destaca as implicações epidemiológicas oriundas da crescente utilização dessas plantas para fins decorativos.
Tópico(s): Plant and animal studies
2002 - UNIVERSIDADE DE SÃO PAULO | Revista de Saúde Pública
Produção Nacional
Revisado por pares
Sérgio Pereira Braz, Domício do Nascimento, Reinaldo Bertola Cantarutti, Adair José Regazzi, Carlos Eugênio Martins, Dilermando Miranda da Fonseca, Rodrigo Amorim Barbosa,
O experimento foi conduzido na estação experimental da EMBRAPA/Gado de Leite, em Coronel Pacheco, na Zona da Mata de Minas Gerais, com o objetivo de avaliar os aspectos quantitativos do processo de reciclagem dos nutrientes pelas fezes de bovinos em pastejo. Utilizou-se uma área de 1,21 ha em uma pastagem de Brachiaria decumbens, já estabelecida. Foi verificado que, durante as 10 semanas do período experimental, ocorreram variações significativas nos teores de nitrogênio e magnésio na forrageira, ...
Tópico(s): Growth and nutrition in plants
2002 - Sociedade Brasileira de Zootecnia | Revista Brasileira de Zootecnia
Produção Nacional
Revisado por pares
José Maurício Machado Pires, Jorge Carvalho de Lena, Carlos Cardoso Machado, Reginaldo Sérgio Pereira,
Foram estudadas amostras de resíduo sólido da Barragem de Germano, da Samarco Mineração S.A. Tal barragem localiza-se no município de Mariana-MG. Sua principal função é coletar os efluentes do tratamento do minério de ferro processado no Complexo de Germano. Este resíduo foi submetido a testes de classificação, de acordo com as Normas ABNT 10004, 10005, 10006 e 10007. Constatou-se que o resíduo é classe III (inerte) e que os testes mostraram a grande capacidade deste material na retenção de metais ...
Tópico(s): Minerals Flotation and Separation Techniques
2003 - Sociedade de Investigações Florestais | Revista Árvore
Paulo Sérgio Pereira da Silva, Pierre Rouchon,
This work considers the open-loop control problem of steering a two level quantum system from an initial to a final condition. The model of this system evolves on the state space SU(2), having two inputs that correspond to the complex amplitude of a resonant laser field. A symmetry preserving flat output is constructed using a fully geometric construction and quaternion computations. Simulation results of this flatness-based open-loop control are provided.
Tópico(s): Quantum optics and atomic interactions
2008 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Automatic Control
Produção Nacional
Revisado por pares
Paulo Sérgio Pereira, Suzelei de Castro França, Paulo Vinicius Anderson de Oliveira, Camila Moniz de Souza Breves, Sarazete Izidia Vaz Pereira, Suely Vilela Sampaio, Auro Nomizo, Diones Aparecida Dias,
This work describes the isolation and structural determination of pharmacological compounds present in the bark of roots of Tabernaemontana catharinensis (Apocynaceae). Among the 27 substances detected 12 were identified as terpenoid-indole alkaloids, 2 steroids and 13 pentacyclic triterpenes. Structures were outlined based on HMQC, COSY, DEPT, 13C, and ¹H NMR data and MS. Spectral data of indole alkaloids were reviewed. An in vitro screening of the extracts and isolated compounds was carried out. ...
Tópico(s): Berberine and alkaloids research
2008 - Brazilian Chemical Society | Química Nova
Produção Nacional
Revisado por pares
Elaine Christine Dantas Moisés, Luciana de Barros Duarte, Ricardo de Carvalho Cavalli, Maria Paula Marques, Vera Lúcia Lanchote, Geraldo Duarte, Sérgio Pereira da Cunha,
Tópico(s): Inflammatory mediators and NSAID effects
2008 - Springer Science+Business Media | European Journal of Clinical Pharmacology
Produção Nacional
Revisado por pares
RC De Paula, EF Sanchez, TR Costa, Carlos Henrique Gomes Martins, Paulo Sérgio Pereira, Miriam Vergínia Lourenço, Andreimar M. Soares, AL Fuly,
Snakebites comprise a serious health problem in several countries due to their global incidence, which exceeds 2.5 million per year, and the elevated number of victim fatalities. To counteract envenomations, antivenoms have been used regularly for more than a century. Apart from side effects including anaphylactic reactions, antivenoms are not able to efficiently neutralize local tissue damage, which contributes to increasing the severity and morbidity observed in patients. This fact, in turn, may ...
Tópico(s): Healthcare and Venom Research
2010 - BioMed Central | The Journal of venomous animals and toxins including tropical diseases
Sérgio Pereira, Sofía Pedroso, La Salete Martins, Paula Motta dos Santos, Manuela Almeida, Cláudia Freitas, L. Dias, Jorge Dores, R. Almeida, A. Castro Henriques, Manuel Teixeira,
Tópico(s): Parathyroid Disorders and Treatments
2010 - Elsevier BV | Transplantation Proceedings