J.F.D. Adams, Sergio Undurraga, Sidney Lightman, Morteza Kakhi, John M. Austes, R.G. Lasse, Robert Kirkwood,
... Nine into One Authority to act Unless Mario Soares does something soon about Portugal's economy, someone ...
1976 - Gale Group | The Economist

Tales Miler Soares, Sérgio Nascimento Duarte, Ênio Farias de França e Silva, Ralini Ferreira de Mélo, Cristiano Jorge, Áureo Santana de Oliveira,
... WATER USE IN LETTUCE HYDROPONIC PRODUCTION Tales Miler Soares; Sergio Nascimento Duarte; Ênio Farias de França e Silva; ...
Tópico(s): Innovations in Aquaponics and Hydroponics Systems
2009 - UNIVERSIDADE EST.PAULISTA JÚLIO DE MESQUITA FILHO | Irriga
Catarina Tomás, Emanuel Oliveira, DANIEL WALLACE ASSIS DE SOUSA, Matheus Uba Chupel, Guilherme Eustáquio Furtado, Clara Rocha, Ana Teixeira, Pedro Lopes Ferreira, C. Alves, Stefan Gisin, Elisabete Catarino, Nelma Carvalho, Tiago Coucelo, Luís Américo Silva Bonfim, Carina Silva, Débora Franco, Jesús Alcoba González, Maria Helena de Agrela Gonçalves Jardim, Rita Silva, Cristina Lavareda Baixinho, Ma Helena Presado, Ma Fátima Marques, Mário E. Cardoso, Marina Cunha, Joana Mendes, Ana Xavier, Ana Galhardo, Margarida Couto, João Frade, Carla Nunes, João R. Mesquita, María Säo José Nascimento, Guilherme Gonçalves, Conceição Castro, Alice Mártires, M. João Monteiro, Conceição Rainho, Francisco P. Caballero, Fátima M. Monago, José T. Guerrero, Rocio M. Monago, Africa P. Trigo, Milagros L. Gutierrez, Gemma M. Milanés, Mercedes G. Reina, Ana G. Villanueva, Ana S. Piñero, Isabel R. Aliseda, Francisco Buitrago Ramírez, Andrea Ribeiro, Ana Quelhas, Maria Conceição Manso, Francisco P. Caballero, José T. Guerrero, Fátima M. Monago, Rafael Brito Santos, Nuria R. Jimenez, Cristina G. Nuñez, Inmaculada Rodríguez Gómez, Ma Jose L. Fernandez, Laura A. Marquez, Ana L. Moreno, Ma Jesus Tena Huertas, Francisco Buitrago Ramírez, Daniel Seabra, Ma Céu Salvador, Luciene Muniz Braga, Pedro Parreira, Anabela Salgueiro‐Oliveira, Cristina Arreguy-Sena, Bibiana F. Oliveira, Ma Adriana Henriques, Joana Santos, Sara Lebre, Alda Marques, Clarinda Festas, Sandra Rodrigues, Andrea Ribeiro, José Lumini‐Oliveira, Ana Gabriela Figueiredo, Francisco J. Hernandez-Martinez, Liliana Campi, Ma Pino Quintana-Montesdeoca, Juan F. Jimenez-Diaz, Bienvenida C. Rodriguez-De-Vera, Alexandra Parente, Ma Augusta Mata, Ana Ma Pereira, Adília Fernandes, Manuel Brás, Ma Rosário Pinto, Pedro Parreira, Marta Lima Basto, Ana C. Rei, Lisete Mónico, Gilberta Sousa, Clementina Morna, Otília Freitas, Gregório Freitas, Ana Carolina Gomes Jardim, Rita P. Vasconcelos, Lina G. Horta, Roger dos Santos Rosa, Luís Fernando Kranz, Rita C. Nugem, Mariana Santiago Siqueira, Ronaldo Bordin, Rosiane Kniess, Josimari Telino de Lacerda, Joana Guedes, Idalina Machado, Sidalina Almeida, Adriano Zilhão, Hélder Alves, Óscar Ribeiro, Ana Paula Martins Amaral, Ana Maria Ribeiro dos Santos, Joana Monteiro, Ma Clara Rocha, Rui Cruz, Ana Paula Martins Amaral, Marina Lourenço, Ma Clara Rocha, Rui Cruz, Sandra Regina Masetto Antunes, Verónica Mendonça, Isabel Andrade, Nádia Osório, Ana Valado, Armando Caseiro, Antonio Padua y Gabriel, Anabela Correia Martins, Fernando Mendes, Lídia Cabral, Manuela Ferreira, Amadeu Gonçalves, Tatiana Durão D`Ávila Luz, Leonardo Gomes de Oliveira Luz, Raúl A. Martins, Alice Murteira Morgado, Maria da Luz Vale-Dias, Rui Porta-Nova, Tânia Cristina Malezan Fleig, Éboni Marília Reuter, Miriam Beatris Froemming, Sabrina Luciane Camara Guerreiro, Lisiane Lisbôa Carvalho, Daniel Guedelha, Pedro S. Coelho, A.T. Pereira, António Calha, Raúl Cordeiro, Ana Gonçalves, Ana Certo, Ana Cristina Araújo de Andrade Galvão, Ma Augusta Mata, Aline Welter, Elayne Crestani Pereira, Sandra Aparecida Ribeiro, Márcia Regina Kretzer, Juan-Fernando Jiménez-Díaz, Carla Jiménez-Rodríguez, Francisco-José Hernández-Martínez, Bienvenida-Del-Carmen Rodríguez-De-Vera, Alexandre Marques-Rodrigues, Patrícia Brazil Pereira Coelho, Tiago Bernardes, Alexandre de Araújo Pereira, Patrícia Sousa, João Ghizzo Filho, Nazaré Otília Nazário, Márcia Regina Kretzer, Odete Amaral, António Garrido, Nélio Veiga, Carla Nunes, Ana Rita Pedro, Carlos Pereira, António Almeia, Hélder Miguel Fernandes, Carlos Vasconcelos, Nélson Sousa, Víctor Machado Reis, M. João Monteiro, Romeu Mendes, Isabel Pinto, Tânia C. S. P. Pires, João Gama, Vera Preto, Norberto Silva, Carlos Pires Magalhães, Matilde Martins, Mafalda Duarte, Constança Paúl, Ignácio Martín, Arminda Pinheiro, S. Xavier, J. Azevedo, E. Bento, C. Marques, M. Marques, A. Macedo, A.T. Pereira, José Pedro Almeida, António Almeida, Josiane Alves, Nélson Sousa, Francisco Saavedra, Romeu Mendes, Ana S. Maia, Michelle Teixeira Oliveira, Anderson Reis de Sousa, Paulo P. Ferreira, Luci S. Lopes, Eujcely C. Santiago, Sílvia Monteiro, Ângelo Jesus, Armanda Colaço, Antônio Ivo de Carvalho, Rita P. Silva, Agostinho Cruz, Ana Ferreira, Catarina Marques, João Paulo Figueiredo, Susana Paix�ão, Ana Ferreira, Carla Lopes, Fernando Moreira, João Paulo Figueiredo, Ana Ferreira, Diana Ribeiro, Fernando Moreira, João Paulo Figueiredo, Susana Paix�ão, Telma Fernandes, Diogo Amado, Jéssica Denise Vieira Leal, Marcelo Costa Velho Mendes de Azevedo, Sónia Ramalho, Catarina Mangas, Jaime Ribeiro, Rita Maria de Abreu Gonçalves, Amélia Fernandes Nunes, Ana Rita Tuna, Carlos Martins, Henriqueta D. Forte, Cláudia Costa, José António Tenedório, Paula Santana, José Augusto Andrade, Joana Pinto, C. Campofiorito, S. C. Nunes, Ana Sofia Carmo, A. Kaliniczenco, BARBARA DE LIMA ALVES, Francisco Mendes, Carlos Jesus, Felipe Paiva Fonseca, Flávia de Sousa Gehrke, Carlos Albuquerque, Rita Carla Pereira Batista, Madalena Cunha, António Dias, Olivério Ribeiro, Rosa Maria Grangeiro Martins, Teresa Madeira, Catarina Peixoto-Plácido, Nuno Rebelo dos Santos, Osvaldo Santos, Astrid Bergland, Asta Bye, Carla Lopes, Violeta Alarcão, Beatriz Goulão, Nuno Mendonça, Paulo Nicola, J. Gorjão Clara, João Gomes, Ana Querido, Catarina Tomás, Daniel Carvalho, Marina Cordeiro, Marlene Rosa, Alda Marques, Daniela Brandão, Óscar Ribeiro, Lia Araújo, Constança Paúl, Beatriz Minghelli, Sylvina Richaud, Ana Laura Mendes, Joana Marta‐Simões, Inês A. Trindade, Cláudia Ferreira, Teresa Carvalho,
... Laboratory: Pedagogical, dialogic and critical project Ana Torres, Sérgio Soares, Margarida Ferreira, Pedro Graça P23 Job satisfaction of ...
BioMed Central

Juliana Saraiva, Micael Soares de França, Sérgio Soares, Fernando J.C.L. Filho, Renata M.C.R. de Souza,
Object-Oriented Programming is one of the most used paradigms. Complementarily, the software maintainability is considered a software attribute playing an important role in quality level. In this context, Object-Oriented Software Maintainability (OOSM) has been studied through years, and many researchers have proposed a large number of metrics to measure it. Consequently, the decision-making process about which metrics can be adopted in experiments on OOSM is a hard task. Therefore, a metrics' categorization ...
Tópico(s): Advanced Software Engineering Methodologies
2015 - Elsevier BV | Journal of Systems and Software

Saulo L. da Silva, Carlos A. Dias‐Junior, Paulo A. Baldasso, Daniela D’Amico, Bruna Mara Aparecida de Carvalho, A. Garanto, Gerardo Acosta, Eliandre de Oliveira, Fernando Alberício, Andreimar M. Soares, Sérgio Marangoni, Rodrigo R. Resende,
Crotalus oreganus abyssus is a rattlesnake that is usually found in the Grand Canyon, United States of America. Knowledge regarding the composition of C. o. abyssus venom is scarce. New natriuretic peptides (NPs) have been isolated and characterized from the venoms of members of the Crotalinae family. The NP family comprises three members, ANP (atrial natriuretic peptide), BNP (b-type natriuretic peptide) and CNP (c-type natriuretic peptide), and has an important role in blood pressure regulation and ...
Tópico(s): Insect and Pesticide Research
2012 - Elsevier BV | Peptides
Elena Sánchez‐Zapata, Juana Fernández‐López, José Ángel Pérez‐Álvarez, José Soares, Sérgio Sousa, Ana Gomes, Manuela Pintado,
Tiger nut milk ("horchata") liquid co-products (TNLC) were evaluated as carbon source for probiotic bacteria (Lactobacillus acidophilus and Bifidobacterium animalis) growth by screening via microplate assay and determination of viable cells and metabolic activity. Based on MRS five different basal media were prepared ((i) without carbon source, (ii) with 2% (w/v) glucose, (iii) with 2% (w/v) FOS, (iv) with 2% (v/v) TNLC and (v) 3% (v/v) TNLC). Additionally, reconstituted TNLC was also used as basal medium. For ...
Tópico(s): Microbial Metabolic Engineering and Bioproduction
2012 - Elsevier BV | Food and Bioproducts Processing

Antônio Augusto Lopes, Alessandra Costa Barreto, Nair Yukie Maeda, Cristina Cícero, R.P.S. Soares, Sérgio Paulo Bydlowski, Stuart Rich,
Biomarkers have been identified for pulmonary arterial hypertension, but are less well defined for specific etiologies such as congenital heart disease-associated pulmonary arterial hypertension (CHDPAH). We measured plasma levels of eight microvascular dysfunction markers in CHDPAH, and tested for associations with survival. A cohort of 46 inoperable CHDPAH patients (age 15.0 to 60.2 years, median 33.5 years, female:male 29:17) was prospectively followed for 0.7 to 4.0 years (median 3.6 years). Plasma ...
Tópico(s): Heart Failure Treatment and Management
2011 - Associação Brasileira de Divulgação Científica | Brazilian Journal of Medical and Biological Research

João Paulo Oliveira–Costa, Juliana Silva Zanetti, Giórgia Gobbi da Silveira, Danilo Figueiredo Soave, Lucinei Roberto Oliveira, Verônica A Zorgetto, Fernando Augusto Soares, Sérgio Zucoloto, Alfredo Ribeiro‐Silva,
Abstract Background Cancer stem cell (CSC) hypothesis postulates that tumors are maintained by a self-renewing CSC population that is also capable of differentiating into non-self-renewing cell populations that constitute the bulk of tumor. Stem cells renewal and differentiation can be directly influenced by the oxygen levels of determined tissues, probably by the reduction of oxidative DNA damage in hypoxic regions, thus leading to a friendlier microenvironment, regarding to clonal expansion and ...
Tópico(s): Cancer Genomics and Diagnostics
2011 - BioMed Central | Diagnostic Pathology

Janaína Cristiana de Oliveira Crispim, Társia Giabardo Alves Silva, Francisco José Dutra Souto, Fernanda Fernandes Souza, Carmen Lucia Bassi, Christiane Pienna Soares, Sérgio Zucoloto, Philippe Moreau, Ana de Lourdes Candolo Martinelli, Eduardo Antônio Donadi,
Chronic hepatitis C virus (HCV) infection is a worldwide health problem that may evolve to cirrhosis and hepatocellular carcinoma. Incompletely understood immune system mechanisms have been associated with impaired viral clearance. The nonclassical class I human leukocyte antigen G (HLA-G) molecule may downregulate immune system cell functions exhibiting well-recognized tolerogenic properties. HCV genotype was analyzed in chronic HCV-infected patients. Because HLA-G expression may be induced by certain ...
Tópico(s): Pregnancy and Medication Impact
2011 - Elsevier BV | Human Immunology

Cliciane Guadalupe de Jesus, Cristiane Maria Sampaio Forte, Karen Wohnrath, Christiana Andrade Pessôa, Janete E. Soares, Sérgio Toshio Fujiwara, Pedro de Lima‐Neto, Adriana N. Correia,
Abstract A (SiPy + Cl − /CuTsPc) 5 layer‐by‐layer film was employed for the electroanalytical determination of promethazine hydrochloride in BR buffer pH 5.0 with peaks at 0.48 and 0.79 V. After optimisation of the square‐wave parameters ( f =100 s −1 , a =40 mV and Δ E s =2 mV), the peak at 0.79 V was used for quantification and a detection limit of 8.71×10 −9 mol L −1 and a quantification limit of 9.31×10 −8 were calculated. The applicability of this procedure was tested on commercial formulations of promethazine ...
Tópico(s): Electrochemical sensors and biosensors
2011 - Wiley | Electroanalysis

Gustavo Arruda Viani, Eduardo Jose Stefano, Francisco V Soares, Sérgio Luís Afonso,
Purpose To evaluate whether the risk of local recurrence depends on the biologic effective dose (BED) or fractionation dose in patients with resectable rectal cancer undergoing preoperative radiotherapy (RT) compared with surgery alone. Methods and Materials A meta-analysis of randomized controlled trials (RCTs) was performed. The MEDLINE, Embase, CancerLit, and Cochrane Library databases were systematically searched for evidence. To evaluate the dose–response relationship, we conducted a meta-regression ...
Tópico(s): Colorectal Cancer Screening and Detection
2010 - Elsevier BV | International Journal of Radiation Oncology*Biology*Physics

Clairton Marcolongo-Pereira, Ana Lúcia Schild, Mauro Pereira Soares, Sérgio Farias Vargas Júnior, Franklin Riet-Corrêa,
Foi realizado um estudo dos defeitos congênitas diagnosticados em bovinos, ovinos e bubalinos mediante revisão dos protocolos de necropsia do Laboratório Regional de Diagnóstico da Faculdade de Veterinária da Universidade Federal de Pelotas entre 1978 e 2009. A ocorrência de defeitos congênitos em bovinos, ovinos e bubalinos representou 0,88%, 0,36% e 7,54% respectivamente, de todos os materiais dessas espécies recebidos. Em bovinos os defeitos esporádicos representaram 45,83% dos diagnósticos, ...
Tópico(s): Plant Toxicity and Pharmacological Properties
2010 - Colégio Brasileiro de Patologia Animal (CBPA) | Pesquisa Veterinária Brasileira

Elson S. Alvarenga, S. A. Silva, L.C.A. Barosa, Antônio J. Demuner, Adriano Guimarães Parreira, Rosy Iara Maciel de Azambuja Ribeiro, Silvana Marcussi, Jaqueline Maria Siqueira Ferreira, Rodrigo R. Resende, Paulo Afonso Granjeiro, J.A. Silva, Andreimar M. Soares, Sérgio Marangoni, Saulo L. da Silva,
Several sesquiterpene lactone were synthesized and their inhibitive activities on phospholipase A(2) (PLA(2)) from Bothrops jararacussu venom were evaluated. Compounds Lac01 and Lac02 were efficient against PLA(2) edema-inducing, enzymatic and myotoxic activities and it reduces around 85% of myotoxicity and around 70% of edema-inducing activity. Lac05-Lac08 presented lower efficiency in inhibiting the biological activities studied and reduce the myotoxic and edema-inducing activities around only ...
Tópico(s): Bioactive Natural Diterpenoids Research
2010 - Elsevier BV | Toxicon
M. Fátima Leite, Giovanni Corso, Sónia Sousa, Fernanda Milanezi, Luís Pedro Afonso, Rui Henrique, José Manuel Soares, Sérgio Castedo, Fátima Carneiro, Giandomenico Roviello, Carla Oliveíra, Raquel Seruca,
Microsatellite instability (MSI) is a major pathway involved in gastric carcinogenesis occurring in 20% of gastric cancer (GC). However, it is not clear whether MSI phenotype preferentially occurs in the sporadic or familial GC, when stringent inclusion criteria are used. The aim of this study was to compare the frequency of MSI and hypermethylation of MLH1 promoter in a large series of familial GC patients (non-HNPCC and non-CDH1-related) and sporadic cases. Additionally, we analysed the immunoexpression ...
Tópico(s): Cholangiocarcinoma and Gallbladder Cancer Studies
2010 - Wiley | International Journal of Cancer

Lucinei Roberto Oliveira, João Paulo Oliveira–Costa, Iana Mizumukai de Araújo, Danilo Figueiredo Soave, Juliana Silva Zanetti, Fernando Augusto Soares, Sérgio Zucoloto, Alfredo Ribeiro‐Silva,
J Oral Pathol Med (2011) 40: 135–142 Background: The presence of cancer stem cell (CSC) antigens can be evidenced in some human tumors by phenotypic analysis through immunostaining. This study aims to identify a putative CSC immunophenotype in oral squamous cell carcinoma (OSCC) and determine its influence on prognosis. Methods: The following data were retrieved from 157 patents: age, gender, primary anatomic site, smoking and alcohol intake, recurrence, metastases, histologic classification, treatment, ...
Tópico(s): Cancer, Hypoxia, and Metabolism
2010 - Wiley | Journal of Oral Pathology and Medicine

Lucia Maria Brum-Soares, Sérgio Salles Xavier, Andréa Silvestre de Sousa, José Borges-Pereira, João Marcos Bemfica Barbosa Ferreira, Inez Ribeiro Costa, Ângela Cristina Veríssimo Junqueira, José Rodrigues Coura,
INTRODUÇÃO: Foi realizado um estudo soroepidemiológico e clínico em 152 indivíduos residentes no município de Barcelos, Estado do Amazonas. Avaliou-se a soroprevalência da infecção chagásica e a morbidade da doença de Chagas. MÉTODOS: Os testes sorológicos foram a imunofluorescência indireta, ELISA convencional e recombinante e o Tesa-blot. Foram considerados soropositivos 38 pacientes, duvidosos 31 e soronegativos negativos 83. Os 38 casos soropositivos foram pareados com 38 controles soronegativos ...
Tópico(s): Research on Leishmaniasis Studies
2010 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
Lúcia Roque, Paula Gomes, Cecília Correia, Paula Soares, Jorge Soares, Sérgio Castedo,
Cytogenetic study of 14 thyroid nodular hyperplasias revealed a hyperdiploid karyotype in two cases (14%) and a normal chromosomal complement in the remaining cases. Some of the numerical alterations found were identical to the ones considered characteristic of a subset of thyroid adenomas (+;5, +;7, +;9, +;12, +;14, and +;16). Our findings suggest that the cytogenetic events involved in the pathogenesis of thyroid hyperplastic lesions and benign tumors may be closely related, which supports the hypothesis of ...
Tópico(s): Head and Neck Anomalies
1993 - Elsevier BV | Cancer Genetics and Cytogenetics
Lúcia Roque, Ana Clode, Jorge Soares, Sérgio Castedo,
Abstract The cytogenetic study of a follicular thyroid adenoma revealed a t(5;19)(q13;q13.3). This is the second report of a translocation between chromosomes 5 and 19 in a thyroid follicular adenoma.
Tópico(s): Genomic variations and chromosomal abnormalities
1992 - Wiley | Genes Chromosomes and Cancer
Filipa Rafael, Maria Dias Rodrigues, José Bellver, Mariana Canelas‐Pais, Nicolás Garrido, Juan A. García-Velasco, Sérgio Reis Soares, Samuel Santos‐Ribeiro,
For a woman with infertility and overweight/obesity, can infertility treatment be postponed to first promote weight loss?Advice regarding a delay in IVF treatment to optimize female weight should consider female age, particularly in women over 38 years for whom only substantial weight loss in a short period of time (3 months) seems to provide any benefit.Body weight excess and advanced age are both common findings in infertile patients, creating the dilemma of whether to promote weight loss first ...
Tópico(s): Reproductive Health and Technologies
2023 - Oxford University Press | Human Reproduction
Leonel J. R. Nunes, António Curado, Luís Graça, Salete Soares, Sérgio Ivan Lopes,
Indoor radon exposure is raising concerns due to its impact on health, namely its known relationship with lung cancer. Consequently, there is an urgent need to understand the risk factors associated with radon exposure, and how this can be harmful to the health of exposed populations. This article presents a comprehensive review of studies indicating a correlation between indoor radon exposure and the higher probability of occurrence of health problems in exposed populations. The analyzed studies ...
Tópico(s): Radioactive contamination and transfer
2022 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health

Morgana Macedo Azevedo da Rosa, Guilherme Paim, Patrícia da Costa, Eduardo Costa, Rafael Soares, Sérgio Bampi,
Addition units are widely used in many computational kernels of several error-tolerant applications such as machine learning and signal, image, and video processing. Besides their use as stand-alone, additions are essential building blocks for other math operations such as subtraction, comparison, multiplication, squaring, and division. The parallel prefix adders (PPAs) is among the fastest adders. It represents a parallel prefix graph consisting of the carry operator nodes, called prefix operators ( ...
Tópico(s): Ferroelectric and Negative Capacitance Devices
2022 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Very Large Scale Integration (VLSI) Systems

Camilla Ioshida Vasconcelos, André Cronemberger Andrade, Normanda Souza‐Melo, Juliana T. Maricato, Patrícia Xander, Wagner L. Batista, Rodrigo Pedro Soares, Sérgio Schenkman, Ana Cláudia Torrecilhas,
All extracellular forms of Trypanosoma cruzi, the causative agent of Chagas disease, release extracellular vesicles (EVs) containing major surface molecules of the parasite. EV release depends on several mechanisms (internal and external). However, most of the environmental conditions affecting this phenomenon are still unknown. In this work, we evaluated EV release under different stress conditions and their ability to be internalized by the parasites. In addition, we investigated whether the release ...
Tópico(s): Galectins and Cancer Biology
2021 - Hindawi Publishing Corporation | Journal of Immunology Research

Marcelo de Oliveira Soares, Sergio Rossi, Anne Rebouças Gurgel, Caroline Costa Lucas, Tallita Cruz Lopes Tavares, Beatriz Diniz, Caroline Vieira Feitosa, Emanuelle Fontenele Rabelo, Pedro Henrique Cipresso Pereira, Ruy Kenji Papa de Kikuchi, Zelinda M.A.N. Leão, Igor Cruz, Pedro Bastos de Macêdo Carneiro, Lorenzo Álvarez‐Filip,
The hydrodynamic study of the littoral sector between Cumbuco and Matões, NW coast of Ceará Sstate, was carried out through an empirical method that makes use of a graph-based refraction diagram associated with fi eld work.This procedure has also considered the the coastal geometry infl uence on geomorphogenesis processes, where wind and waves exert a fundamental role.Modelling of the intensity and direction of the longshore transport has shown that the prevailing direction is SE-SW and its intensity ...
Tópico(s): Marine Ecology and Invasive Species
2021 - Elsevier BV | Ocean & Coastal Management

Ana Cláudia Torrecilhas, Rodrigo Pedro Soares, Sérgio Schenkman, Christopher Fernández-Prada, Martin Olivier,
Trypanosoma cruzi, Trypanosoma brucei and Leishmania (Trypanosomatidae: Kinetoplastida) are parasitic protozoan causing Chagas disease, African Trypanosomiasis and Leishmaniases worldwide. They are vector borne diseases transmitted by triatomine bugs, Tsetse fly, and sand flies, respectively. Those diseases cause enormous economic losses and morbidity affecting not only rural and poverty areas but are also spreading to urban areas. During the parasite-host interaction, those organisms release extracellular ...
Tópico(s): Research on Leishmaniasis Studies
2020 - Frontiers Media | Frontiers in Cellular and Infection Microbiology

Bruno Andrade, Fernanda de Souza Rangel, Naiane Oliveira Santos, Andria dos Santos Freitas, Wagner Rodrigues de Assis Soares, Sérgio Siqueira, Debmalya Barh, Aristóteles Goés‐Neto, Alexander Birbrair, Vasco Azevedo,
The SARS-CoV-2 outbreak originally appeared in China in December 2019 and became a global pandemic in March 2020. This infectious disease has directly affected public health and the world economy. Several palliative therapeutic treatments and prophylaxis strategies have been used to control the progress of this viral infection, including pre-(PrEP) and post-exposure prophylaxis. On the other hand, research groups around the world are still studying novel drug prophylaxis and treatment using repurposing ...
Tópico(s): SARS-CoV-2 and COVID-19 Research
2020 - Frontiers Media | Frontiers in Pharmacology

Ana Laura Soares, Sérgio D. Simon, Luíz Henrique Gebrim, Afonso Celso Pinto Nazário, Marise Lazaretti‐Castro,
Tópico(s): Cancer Diagnosis and Treatment
2019 - Springer Science+Business Media | Supportive Care in Cancer
Gisela H. Maia, Joana I. Soares, Sérgio G. Almeida, Juliana Moysés Leite, Helena X. Baptista, Nikolay Lukoyanov, Cátia Brazete, Nikolay Lukoyanov,
Studies in animal models of epilepsy revealed compromised serotonin (5-HT) transmission between the raphe nuclei and the brain limbic system. The goal of the present study was to evaluate the effects of epilepsy on the structural integrity of the dorsal (DR) and median (MnR) raphe nuclei and on the morphology of serotonergic fiber terminals in the dentate gyrus (DG), infralimbic cortex (IL) and medial septum (MS). The study was performed in adult Wistar rats using the kainate (9.5 mg/kg) status epilepticus ( ...
Tópico(s): Neurological disorders and treatments
2019 - Elsevier BV | Brain Research Bulletin

Vanessa Fátima Gazoni, Sikiru Olaitan Balogun, Karuppusamy Arunachalam, Darley Maria Oliveira, Valdir Cechinel Filho, Samara Rosolem Lima, Édson Moleta Colodel, Ilsamar Mendes Soares, Sérgio Donizeti Ascêncio, Domingos Tabajara de Oliveira Martins,
Simaba ferruginea A. St.-Hil., Simaroubaceae, popularly known as "calunga" is a typical subtropical shrub used in Central Brazil mainly for infection, anti-inflammatory, analgesic and gastric duodenal-ulcers. It presents in its composition the alkaloid canthin-6-one, an alkaloid indole β-carboxylic. This study aims to investigate the toxicity, antimicrobial activities of methanol extract of Simaba ferruginea (MESf) and canthin-6-one by using different experimental models. The present study evaluated ...
Tópico(s): Phytochemistry Medicinal Plant Applications
2018 - Elsevier BV | Journal of Ethnopharmacology

Jaqueline Cibene Moreira Borges, Khalid Haddi, Eugênio E. Oliveira, Bruno Andrade, Vitor L. Nascimento, Tarcísio Silva Melo, Julcemar Didonet, José Carlos Tavares Carvalho, Alex Sander Rodrigues Cangussu, Ilsamar Mendes Soares, Sérgio Donizeti Ascêncio, Nádia Rezende Barbosa Raposo, Raimundo Wagner de Souza Aguiar,
The use of wood residues and their extracts as sources for bioactive molecules not only helps to reduce the environmental impacts of the wastage produced by timber industry but also provide innumerous biotechnological application opportunities, including the development of novel insecticide products. Here, the insecticidal and repellent (in gel and cream formulations) potential of wood extracts of the Neotropical plant "purple ipê", Tabebuia heptaphylla (Bignoniaceae) against the mosquitoes Aedes aegypti ...
Tópico(s): Insect Pest Control Strategies
2018 - Elsevier BV | Industrial Crops and Products

Danielle Ayr Tavares de Almeida, Suellen Iara Guirra Rosa, Thais Campos Dias da Cruz, Eduarda Pavan, Amílcar Sabino Damazo, Amílcar Soares, Sérgio Donizeti Ascêncio, Antonio Macho, Domingos Tabajara de Oliveira Martins,
Mandevilla longiflora, popularly known as "velame" in central Brazil, is a subshrub widely distributed in South America. Its xylopodium is used in the form of a decoction or infusion to treat inflammation and other ailments.This study aimed to evaluate the anti-inflammatory potential of M. longiflora in an in vivo model of ovalbumin-induced immediate hypersensitivity, identifying its effects on leukocyte infiltration, IgE and LTB4 levels, and Th2 cytokine production. In addition, HPLC fingerprint ...
Tópico(s): Olfactory and Sensory Function Studies
2017 - Elsevier BV | Journal of Ethnopharmacology