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Artigo Acesso aberto Brasil Produção Nacional Revisado por pares

Daniela Coelho dos Santos, Jamal Rafique, Sumbal Saba, Valdelúcia M.A.S. Grinevicius, Danilo Wilhelm Filho, Ariane Zamoner, Antônio L. Braga, Rozangela Curi Pedrosa, Fabiana Ourique,

... at further investigating the antitumor mechanism of IP-Se-06 (3-((2-methoxyphenyl)selanyl)-7-methyl-2-phenylimidazol[ ... 2-a]pyridine derivative in glioblastoma cells. IP-Se-06 exhibited high cytotoxicity against A172 cells (IC50 = 1. ... and selectivity for this glioblastoma cell. The IP-Se-06 compound has pharmacological properties verified in its ADMET ... BBB) permeability. At low concentration (1 μM), IP-Se-06 induced intracellular redox state modulation with depletion of ... as well as inhibition of NRF2 protein. IP-Se-06 also decreased mitochondrial membrane potential, induced cytochrome c ...

Tópico(s): Redox biology and oxidative stress

2022 - Hindawi Publishing Corporation | Oxidative Medicine and Cellular Longevity

Artigo Acesso aberto Revisado por pares

A. M. Collins, Judith K. Brown, Malik Mujaddad Rehman, Marcia E. Roye,

... renamed EuMV-[Jamaica:StElizabeth:2006], abbreviated EuMV-[JM:SE:06]. The full-length DNA-B clone isolated from ... is the likely DNA-B of EuMV-[JM:SE:06], as it shared a 165-nt CR of ... MX:Yuc:04]. Phylogenetic analyses placed EuMV-[JM:SE:06] in the squash leaf curl virus cluster, as ... revealed that the DNA-A of EuMV-[JM:SE:06] and EuMV-B[MX:Jal:05] are highly ... 1a). DNA-B is available for EuMV-[JM:SE:06] and EuMV-[MX:Yuc:04] only, and they ... Table 2). The 83% identity between EuMV-[JM:SE:06] and EuMV-A[MX:Yuc:04] is in ...

Tópico(s): Plant Pathogenic Bacteria Studies

2009 - Springer Science+Business Media | Archives of Virology

Artigo Brasil Produção Nacional Revisado por pares

Daniela Coelho dos Santos, Jamal Rafique, Sumbal Saba, Gabriela M. Almeida, Tâmila Siminski, Cynthia Pádua, Danilo Wilhelm Filho, Ariane Zamoner, Antônio L. Braga, Rozangela Curi Pedrosa, Fabiana Ourique,

... and in vivo. The selenylated IP named IP‐Se‐06 (3‐((2‐methoxyphenyl)selanyl)‐7‐methyl‐2‐phenylimidazol[ ... this tumor cell line. At nontoxic concentration, IP‐Se‐06 decreased the protein levels of Bcl‐xL and ... B1, cyclin‐dependent kinase 2). In addition, IP‐Se‐06 decreased the number of cells in the S phase. In addition, IP‐Se‐06 led to increased generation of reactive oxygen species, ... antioxidant defenses, and caused DNA fragmentation. Finally, IP‐Se‐06 significantly inhibited the growth of Ehrlich ascites tumors ...

Tópico(s): Synthesis and biological activity

2020 - Wiley | Journal of Biochemical and Molecular Toxicology

Artigo Revisado por pares

Kunal Karia, Irving Waxman, Vani J. Konda, Frank G. Gress, Amrita Sethi, Uzma D. Siddiqui, Reem Z. Sharaiha, Prashant Kedia, Armeen Jamal-Kabani, Monica Gaidhane, Michel Kahaleh,

... for vessels, .16 (SE = .07) for villi, .22 (SE = .06) for dark clumps, .13 (SE = .06) for reticular pattern, .14 (SE = .06) for acinar cells pattern, .06 (SE = .06) for debris, .15 (SE = .03) for interpretation, .13 ( ...

Tópico(s): Gastrointestinal disorders and treatments

2015 - Elsevier BV | Gastrointestinal Endoscopy

Artigo Brasil Produção Nacional Revisado por pares

Gabriela M. Almeida, Jamal Rafique, Sumbal Saba, Tâmila Siminski, Nádia S.R.S. Mota, Danilo Wilhelm Filho, Antônio L. Braga, Rozangela Curi Pedrosa, Fabiana Ourique,

... 2-phenylimidazo[1,2-a]pyridine, named IP-Se-06, showed high cytotoxicity for MCF-7 cells (IC50 = ... of cell cycle. IP-Se-05 and IP-Se-06 were also evaluated for effects on CT-DNA ... at the imidazo[1,2-a]pyridine (IP-Se-06) appears to have a better antitumor effect with ... less necrosis. Overall, the current study established IP-Se-06 more than IP-Se-05 as a potential ...

Tópico(s): Metal complexes synthesis and properties

2018 - Elsevier BV | Biochemical and Biophysical Research Communications

Artigo Acesso aberto Revisado por pares

Demetrius A. Abshire, Dawn K. Wilson, Allison M. Sweeney, Bernardine M. Pinto,

... 07, p = .037), exercise self-concept (B = .28, SE = .06, p < .001), exercise support from friends (B = .12, SE = .06, p = .048), and places for walking and cycling (B = .13, SE = .06, p = .032) were positively associated with exercise motivation. ...

Tópico(s): Obesity, Physical Activity, Diet

2019 - SAGE Publishing | American Journal of Men s Health

Artigo

Jan van der Ende, Frank C. Verhulst, Henning Tiemeier,

... of internalizing problems in adolescence correlated, r = .14, SE = .06, p = .035 with more internalizing disorders in adulthood ... self-reports of internalizing problems correlated r = .14 (SE = .06, p = .033) and r = .13 (SE = .05, p = . ... increases of discrepancies over time correlated, r = .13, SE = .06, p = .036 with more DSM externalizing disorders in ...

Tópico(s): Attention Deficit Hyperactivity Disorder

2020 - American Psychological Association | Journal of Abnormal Psychology

Artigo Acesso aberto

Ricarda Mewes, Boris Friele, Evert Bloemen,

... Diagnostic accuracy with regard to PTSD (AUC=.74; SE=.06; p<.001; 95%-CI=.63-.84) and MD (AUC=.72; SE=.06; p<.001; 95%-CI=.61- .83) was adequate, ...

Tópico(s): Resilience and Mental Health

2018 - International Rehabilitation Council for Torture Victims | Torture Journal

Artigo Revisado por pares

Andrea Too, Catherine Gatien, Stéphanie Cormier,

... and patient depressive symptoms (indirect effect: B = -.19, SE =.06, 95 % CI [-.31, -.09]) and anxious symptoms (indirect effect: B = -.24, SE = .06, 95 % CI [-.35, -.14]), via treatment satisfaction as ...

Tópico(s): Pain Management and Placebo Effect

2020 - Elsevier BV | Patient Education and Counseling

Artigo Revisado por pares

Kristen P. Kremer,

... SE = .05), persisting in college ( OR = 1.40, SE = .06), and taking full-time course loads ( OR = 1.32, SE = .06). They were less likely to attend a 2- ...

Tópico(s): Urban, Neighborhood, and Segregation Studies

2020 - SAGE Publishing | Emerging Adulthood

Artigo Acesso aberto Brasil Produção Nacional

Luís Osmar Braga Schuch, Eliane Maria Kolchinski, Jonas Alex Finatto,

... qualidade. Na implantação do experimento a campo semeou-se 06 sementes por cova e após emergência, realizou-se ...

Tópico(s): Seed Germination and Physiology

2009 - SciELO | Revista Brasileira de Sementes

Artigo Revisado por pares

C. Philip Steuber, Curt I. Civin, J. Krischer, Steven J. Culbert, A H Ragab, F. B. Ruymann, Yaddanapudi Ravindranath, B G Leventhal, Rosemary Wilkinson, TJ Vietti,

... continuation therapy combination at 2 years was .50 (SE = .06), at 3 years was .35 (.04), and at ...

Tópico(s): Childhood Cancer Survivors' Quality of Life

1991 - Lippincott Williams & Wilkins | Journal of Clinical Oncology

Artigo Revisado por pares

Laura Detti, Giancarlo Mari, Masashi Akiyama, Erich Cosmi, Kenneth J. Moise, Theodor Stefor, Mark R. Conaway, Russell L. Deter,

... was not statistically significant (estimated difference = 1.1, SE =.06; P =.08).We have demonstrated that the MCA- ...

Tópico(s): Prenatal Screening and Diagnostics

2002 - Elsevier BV | American Journal of Obstetrics and Gynecology

Artigo Acesso aberto Revisado por pares

Fehmidah Munir, Joanna Yarker, Cheryl Haslam, Helen Long, Stavroula Leka, Amanda Griffiths, S J Cox,

... and long-term sickness absence (β=0.10, SE=.06). Conclusions: To enable individuals to effectively manage both ...

Tópico(s): Employment and Welfare Studies

2007 - Springer Science+Business Media | Journal of Occupational Rehabilitation

Artigo Revisado por pares

Rudy Bowen, Lloyd Balbuena, Carla Leuschen, Marilyn Baetz,

... of worse mental health (OR: 1.17, robust se: .06, p < .01) next to baseline GHQ. The results ...

Tópico(s): Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes

2012 - Elsevier BV | Personality and Individual Differences

Artigo Acesso aberto Revisado por pares

R. Meredith Elkins, Aubrey L. Carpenter, Donna B. Pincus, Jonathan S. Comer,

... accurately distinguishing between the two groups (AUC=.84, SE=.06). Specifically, a cut score of 63 achieved the ...

Tópico(s): Bipolar Disorder and Treatment

2014 - Elsevier BV | Journal of Anxiety Disorders

Artigo Acesso aberto Brasil Produção Nacional

Angélica Miguel SOARES, Jorge Lopes Cavalcante Neto,

... se 3.164 textos na busca inicial, selecionando-se 06 que preencheram os critérios estabelecidos. Observou-se que ...

Tópico(s): Child Development and Digital Technology

2015 - Associação Brasileira de Pesquisadores em Educação Especial | Revista Brasileira de Educação Especial

Artigo Brasil Produção Nacional Revisado por pares

A. F. Faria-Machado, Alba Tres, Saskia M. van Ruth, Rosemar Antoniassi, N. T. V. Junqueira, Paulo Sérgio Nascimento Lopes, H. R. Bizzo,

... unique pequi genotype without endocarp spines (CPAC-PQ-SE-06).

Tópico(s): Ethnobotanical and Medicinal Plants Studies

2015 - American Chemical Society | Journal of Agricultural and Food Chemistry

Artigo Revisado por pares

Andres G. Viana, Laura J. Dixon, Erin C. Berenz, Flint M. Espil,

... was significant for individuals scoring high (b = .25, SE = .06; t(50) = 3.83, p < .01) but not ...

Tópico(s): Child Abuse and Trauma

2016 - American Psychological Association | Psychological Trauma Theory Research Practice and Policy

Artigo Acesso aberto Revisado por pares

Christine M. Guardino, Christine Dunkel Schetter, Calvin J. Hobel, Robin Gaines Lanzi, Peter Schäfer, John M. Thorp, Madeleine U. Shalowitz,

... p = .006) and 12-month postpartum (b = .15, SE = .06, p = .007) adjusting for race/ethnicity, income, education, ...

Tópico(s): Adolescent and Pediatric Healthcare

2016 - Lippincott Williams & Wilkins | Psychosomatic Medicine

Artigo Revisado por pares

Paquito Bernard, Hans Ivers, Marie‐Hélène Savard, Josée Savard,

... SE = .05, p < .05), and TST (β = -.14, SE = .06, p < .05) were significantly associated with a greater ...

Tópico(s): Sleep and Wakefulness Research

2016 - American Psychological Association | Health Psychology

Artigo Revisado por pares

Lela Rankin Williams, Heidi Adams Rueda,

... mismatch resulted in greater couple negativity (B = .16, SE = .06, p = .01), which was associated with self-reported ...

Tópico(s): Attachment and Relationship Dynamics

2016 - Wiley | Journal of Adolescence

Artigo Acesso aberto Revisado por pares

Liat Ayalon, Sharon Shiovitz‐Ezra, Ilan Roziner,

... of memory functioning on loneliness was significant, B(SE) = -.06(.02), p = .01, indicating that lower levels of ...

Tópico(s): Aging and Gerontology Research

2016 - American Psychological Association | Psychology and Aging

Artigo Revisado por pares

Stephanie Dennis, V. G. Allen, K. E. Saker, J. P. Fontenot, Jamal Y. Ayad, Claire Brown,

... clones (3.4 vs 2.8 μg/g; SE, .06). In the second greenhouse experiment, genetically similar E+ ...

Tópico(s): Plant and fungal interactions

1998 - Oxford University Press | Journal of Animal Science

Artigo Revisado por pares

Ajay Manhapra, Ismene L. Petrakis, Robert A. Rosenheck,

... race (Hazards ratio [HR] 1.26; standard error [SE] .06; p.0003), the Charlson index (HR 1.03; ...

Tópico(s): HIV, Drug Use, Sexual Risk

2017 - Wiley | American Journal on Addictions

Artigo Revisado por pares

Vanessa Panaite, Alana Whittington, Alexandra Cowden Hindash,

... in DA among MDDs than controls (B = −.24, SE = .06, t(73) = −4.10, p < .001). Finally, lower ...

Tópico(s): Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes

2017 - Taylor & Francis | Cognition & Emotion

Artigo Acesso aberto Revisado por pares

Joshua P. Aquin, Leslie E. Roos, Jino Distasio, Laurence Y. Katz, Jimmy Bourque, James M. Bolton, Shay‐Lee Bolton, Jacquelyne Y. Wong, Dan Château, Julian M. Somers, Murray W. Enns, Stephen W. Hwang, James Frankish, Jitender Sareen,

... group (i.e., HF vs. TAU; estimate = –.04, SE = .06, P = 0.51). Furthermore, there was no effect ...

Tópico(s): Health disparities and outcomes

2017 - SAGE Publishing | The Canadian Journal of Psychiatry

Artigo Acesso aberto Revisado por pares

Shannon M. Christy, Joseph G. Winger, Catherine E. Mosher,

... perceived barriers to HPV vaccination—indirect effect = −.16, SE = .06, 95% confidence interval [CI] = [−.31, −.06]—and perceived ...

Tópico(s): Adolescent Sexual and Reproductive Health

2017 - SAGE Publishing | Clinical Nursing Research

Artigo Revisado por pares

Ranjan Sudan, Matthew L. Maciejewski, Amber R. Wilk, Ninh T. Nguyen, Jaime Ponce, John M. Morton,

... 9.3 (SE: .03), and SG 5.7 (SE: .06). Resolution of GERD was best for RYGB (odds ...

Tópico(s): Esophageal Cancer Research and Treatment

2017 - Elsevier BV | Surgery for Obesity and Related Diseases