Yan Du, Ying Zhong, Ruilin Ding, Xiaojie Wang, Fenfen Xia, Qian Zhang, Qing Peng,
... immune response to infection. Sepsis-induced myocardial dysfunction (SIMD) is a common complication in patients with severe ... associated with increased mortality. The molecular mechanisms underlying SIMD are complex and not well characterized. Excessive inflammation ... response is one of the major causes of SIMD. Necroptosis is a novel type of cell death ... and inflammation. However, the role of necroptosis in SIMD is not known. Therefore, in this study, we ... analysis to investigate the relationship between necroptosis and SIMD using a mouse model generated by intraperitoneal injection ...
Tópico(s): Cell death mechanisms and regulation
2022 - Frontiers Media | Frontiers in Cellular and Infection Microbiology
Yu Chen, Fu Zhang, Xin Ye, Jingjuan Hu, Xiao Yang, Yao Lin, Bing-Cheng Zhao, Fan Deng, Ke‐Xuan Liu,
Objective Sepsis-induced myocardial dysfunction (SIMD) seriously affects the evolution and prognosis of the sepsis patient. The gut microbiota has been confirmed to play an important role ... changes and roles of the gut microbiota in SIMD have not been reported yet. This study aims ... find the relationship between the gut microbiota and SIMD. Methods The prospective, observational, and 1:1 matched ... to observe gut microbiota profiles from patients with SIMD (n = 18) and matched non-SIMD (NSIMD) patients (n = 18) by 16S rRNA gene ...
Tópico(s): Intensive Care Unit Cognitive Disorders
2022 - Frontiers Media | Frontiers in Cellular and Infection Microbiology
Fiona Davie-Smith, Lorna Paul, Wesley Stuart, Brian Kennon, Robin Young, Sally Wyke,
... A postcode derived Scottish Index of Multiple Deprivation (SIMD) was applied by quintile (SIMD 1 = most deprived). Routine data were collected on ... 53% had diabetes. In total, 67% lived in SIMD 1 and 2 and 11.1% in SIMD 5. Sixty per cent had a transtibial amputation. ... six, and 29% at 12 months. Those in SIMD 1 were significantly younger (62.9 years) than those in SIMD 5 (76.3 years). Significantly more participants with a transfemoral amputation (TFA) lived in SIMD 1 (44%) compared with SIMD 5 (11%) (p = .004). Participation was low (RNLI ...
Tópico(s): Prosthetics and Rehabilitation Robotics
2019 - Elsevier BV | European Journal of Vascular and Endovascular Surgery
Hossein Amiri, Asadollah Shahbahrami,
Single instruction multiple data (SIMD) extensions are one of the most significant capabilities of recent General Purpose Processors (GPPs) which improves the performance of applications ... has its particular Instruction Set Architecture (ISA) and SIMD micro-architecture with different perspectives. Intel expanded SIMD technologies from hardware and software point of view. It has introduced SIMD technologies such as MultiMedia eXtensions (MMX), Streaming SIMD Extensions (SSE), Advanced Vector eXtensions (AVX), Fused Multiply ...
Tópico(s): Interconnection Networks and Systems
2019 - Elsevier BV | Journal of Parallel and Distributed Computing
Han Saem Jeong, Tae Hyub Lee, Cho Hee Bang, Jong-Ho Kim, Soon Jun Hong,
While both sepsis-induced myocardial dysfunction (SIMD) and stress-induced cardiomyopathy (SICMP) are common in patients with sepsis, the pathogenesis of the 2 diseases is different, and they require ... hours of admission.In all, 25 patients with SIMD and 27 patients with SICMP were enrolled. Chronic ... failure (HF) were more prevalent in both the SIMD and SICMP groups than in the control group. In the SIMD and SICMP groups, levels of inflammatory cytokines were ... level was significantly elevated in the SICMP and SIMD group compared to the control group. N-terminal ...
Tópico(s): Cardiac Arrest and Resuscitation
2018 - Wolters Kluwer | Medicine
Ding‐Yong Hong, Yuping Liu, Sheng‐Yu Fu, Jan‐Jan Wu, Wei‐Chung Hsu,
Recent trends in SIMD architecture have tended toward longer vector lengths, and more enhanced SIMD features have been introduced in newer vector instruction ... However, legacy or proprietary applications compiled with short-SIMD ISA cannot benefit from the long-SIMD architecture that supports improved parallelism and enhanced vector ... a dynamic binary translation technique that enables short-SIMD binaries to exploit benefits of new SIMD architectures by rewriting short-SIMD loop code. We propose a general approach that ...
Tópico(s): Interconnection Networks and Systems
2018 - Association for Computing Machinery | ACM Transactions on Embedded Computing Systems
Jinpil Lee, Francesco Petrogalli, G. L. K. Hunter, Mitsuhisa Sato,
... trends in processor design accommodate wide vector extensions. SIMD vectorization is more important than before to exploit ... directives which help compilers produce better code for SIMD auto-vectorization. However, it is hard to optimize the SIMD code performance in OpenMP since the target SIMD code generation mostly relies on the compiler implementation. ... propose a new directive that specifies user-defined SIMD variants of functions used in SIMD loops. The compiler can then use the user-defined SIMD variants when it encounters OpenMP loops instead of ...
Tópico(s): Advanced Data Storage Technologies
2017 - Springer Science+Business Media | Lecture notes in computer science
Amir Morad, Leonid Yavits, Shahar Kvatinsky, Ran Ginosar,
GP-SIMD, a novel hybrid general-purpose SIMD architecture, addresses the challenge of data synchronization by in-memory computing, through combining data storage and massive parallel processing. In this article, we explore a resistive implementation of the GP-SIMD architecture. In resistive GP-SIMD, a novel resistive row and column addressable 4F ... 190F 2 SRAM storage previously proposed for GP-SIMD architecture. The use of the resistive crossbar allows scaling the GP-SIMD from few millions to few hundred millions of ...
Tópico(s): Parallel Computing and Optimization Techniques
2016 - Association for Computing Machinery | ACM Transactions on Architecture and Code Optimization
... an array of structures by efficiently exploiting the SIMD instructions and cache memory of today's processors. Recently, multiway mergesort implemented with SIMD instructions has been used as a high-performance ... values. For sorting an array of structures with SIMD instructions, a frequently used approach is to first ... integer value, sort the key-index pairs using SIMD instructions, then rearrange the records based on the ... key-index pairs. This approach can efficiently exploit SIMD instructions because it sorts the key-index pairs ...
Tópico(s): Advanced Data Storage Technologies
2015 - Association for Computing Machinery | Proceedings of the VLDB Endowment
Thomas Schaub, Simon Moll, Ralf Karrenberg, Sebastian Hack,
... prevalent issue in current and future computing systems. SIMD processors amortize the power consumption of managing the ... multiple data. Therefore, in the past years, the SIMD width has steadily increased, and it is not ... article, we experimentally study the influence of the SIMD width to the execution of data-parallel programs. We investigate how an increasing SIMD width (up to 1024) influences control-flow divergence ... techniques to mitigate them will work on larger SIMD widths. We perform our study on 76 OpenCL ...
Tópico(s): Interconnection Networks and Systems
2015 - Association for Computing Machinery | ACM Transactions on Architecture and Code Optimization
Tomoyuki Endo, Shigeki Kushimoto, Satoshi Yamanouchi, Teruo Sakamoto, Hiroyasu Ishikura, Yasuhide Kitazawa, Yasuhiko Taira, Kazuo Okuchi, Takashi Tagami, Akihiro Watanabe, Junko Yamaguchi, Kazuhide Yoshikawa, Manabu Sugita, Yoichi Kase, Takashi Kanemura, Hiroyuki Takahashi, Y Kuroki, Hiroo Izumino, Hiroshi Rinka, Ryutarou Seo, Makoto Takatori, Tadashi Kaneko, Toshiaki Nakamura, Takayuki Irahara, Nobuyuki Saito,
... into two groups-with sepsis-induced myocardial dysfunction (SIMD) and without SIMD (non-SIMD)-according to a threshold LV ejection fraction (LVEF) ... 0.045) between GEDI and SVV in the SIMD group, whereas this paradoxical correlation was not found in the non-SIMD group and both groups on day 2. To ... and SVV >13% was compared in both the SIMD and non-SIMD groups. SVV ≤13% implies the attainment of cardiac preload optimization. Among patients with SIMD, GEDI was higher in patients with SVV >13% ... SVV ≤13% and SVV >13% in the non-SIMD group on the day of enrollment and both ...
Tópico(s): Climate Change and Health Impacts
2013 - BioMed Central | Journal of Intensive Care
Yongjun Park, Sangwon Seo, Hyunchul Park, Hyoun Kyu Cho, Scott Mahlke,
Single-instruction multiple-data (SIMD) accelerators provide an energy-efficient platform to scale the performance of mobile systems while still retaining post-programmability. The central challenge is translating the parallel resources of the SIMD hardware into real application performance. In scientific applications, ... and non-uniform execution behavior. As a result, SIMD lanes remain idle due to insufficient DLP. To ... this paper proposes a new vectorization pass called SIMD Defragmenter to uncover hidden DLP that lurks below ...
Tópico(s): Advanced Data Storage Technologies
2012 - ACM SIGARCH | ACM SIGARCH Computer Architecture News
Wing-Yee Lo, Daniel Pak-Kong Lun, Wan-Chi Siu, Wendong Wang, Jiqiang Song,
Single instruction multiple data (SIMD) execution is in no doubt an efficient way to exploit the data level parallelism in image and video applications. However, SIMD execution bottlenecks must be tackled in order to ... AVC namely, SATD and subpel interpolation, in conventional SIMD architectures to identify the bottlenecks in traditional approaches. ... on the analysis results, we propose a new SIMD architecture with two novel features: 1) parallel memory ... size and word length support, and 2) configurable SIMD structure. The proposed parallel memory structure allows great ...
Tópico(s): Advanced Data Compression Techniques
2011 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Circuits and Systems for Video Technology
Chun‐Gi Lyuh, Jung-Hee Suk, Ik-Jae Chun, Tae Moon Roh,
... using dynamically partitioned single-instruction multiple-data (DP-SIMD) which is able to process multimedia data. The SIMD processor and parallel SIMD (P-SIMD) processor, which is composed of a number of SIMD processors, are usually used these days. But these ... PUs can process different operations only when every SIMD group operation is predefined. We propose a processor ... method which can partition parallel processors into multiple SIMD-based processors dynamically to enhance efficiency. For performance ...
Tópico(s): Advanced Vision and Imaging
2009 - Electronics and Telecommunications Research Institute | ETRI Journal
Hamed Fatemi, Bart Mesman, Henk Corporaal, Twan Basten, Richard Kleihorst,
... the last two decades, Single Instruction Multiple Data (SIMD) processors have become important architectures in embedded systems ... efficiency. Often the processing elements (PEs) of an SIMD processor are only locally connected. This may result ... to use a fully connected communication network (FC-SIMD) between PEs. However, this solution leads to an ... E.g., the area overhead of an FC-SIMD is more than 100% when the number of ... this paper, we introduce a new type of SIMD architecture, called RC-SIMD, with a reconfigurable communication ...
Tópico(s): Embedded Systems Design Techniques
2006 - IOS Press | Journal of Embedded Computing
D. Talla, Lizy K. John, Doug Burger,
Multimedia SIMD extensions such as MMX and AltiVec speed up media processing; however, our characterization shows that the attributes of current general-purpose processors enhanced with SIMD extensions do not match very well with the ... stream are supporting instructions necessary to feed the SIMD execution units rather than true/useful computations, resulting in the underutilization of SIMD execution units (only 1 to 12 percent of the peak SIMD execution units' throughput is achieved). Contrary to focusing ...
Tópico(s): Embedded Systems Design Techniques
2003 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Computers
Bengt‐Olaf Schneider, J. van Welzen,
SIMD processors have become popular architectures for multimedia. Though most of the 3D graphics pipeline can be implemented on such SIMD platforms in a straightforward manner, polygon clipping tends to cause clumsy and expensive interruptions to the SIMD pipeline. This paper describes a way to increase the efficiency of SIMD clipping without sacrificing the efficient flow of a SIMD graphics pipeline. In order to fully utilize the ... to buffer polygons that need to be clipped. SIMD clipping partitions the actual polygon clipping procedure between ...
Tópico(s): Parallel Computing and Optimization Techniques
1998 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Visualization and Computer Graphics
... for compilers to utilize single instruction, multiple data (SIMD) instructions. Disjoint memory references, arbitrarily misaligned memory references, ... in loops are main challenges to handle for SIMD compilers. Due to those challenges, existing SIMD compilers have excluded loops with array indirection from their candidate loops for SIMD vectorization. However, addressing those challenges is inevitable, since ... work, we propose a method to generate efficient SIMD code for loops containing indirected memory references. We ...
Tópico(s): Algorithms and Data Compression
2012 - Association for Computing Machinery | ACM SIGPLAN Notices
Per Lincoln, Narciso Martı́-Oliet, José Meseguer, Livio Ricciulli,
... to compile various constructs of Simple Maude onto SIMD and MIMD/SIMD massively parallel architectures, and in particular onto the Rewrite Rule Machine (RRM), a special purpose MIMD/SIMD architecture for rewriting. We then demonstrate how to compile SIMD graph rewriting onto MIMD/SIMD architectures, and discuss mapping 3-D structures into 2-D SIMD meshes. Finally, we sketch the compilation of object-oriented rewriting into efficient MIMD/SIMD code. We thus show that Simple Maude is ...
Tópico(s): Software Engineering Research
1994 - Springer Science+Business Media | Lecture notes in computer science
Ru Chen, Xiaotao Hu, Wenè Wang, Hui Ran, Tianyuan Song, Yinyin Guo,
... DI can diagnose grapevine water status in time, SIMDS and SIDI have the advantages of sensitivity and ... the R2 values of the regression equations of SIMDS and SIDI with SWP and RWC were high, ... a very significant level (p < 0.01). Thus, SIMDS and SIDI are more suitable for the diagnosis of grapevine water status. The SIMDS peaked at the fruit expansion stage, reaching 0. ... the flowering stage were similar to those of SIMDS, while the correlation between SIDI and the soil moisture content was higher than that of SIMDS. It can be concluded that that SIDI is ...
Tópico(s): Irrigation Practices and Water Management
2021 - Multidisciplinary Digital Publishing Institute | Horticulturae
Wei Cheng, Yun Long, Hao Wang, Wen Han, Jiahui Zhang, Na Cui,
BackgroundSepsis-induced myocardial dysfunction (SIMD) is a life-threatening complication of sepsis. Mammalian target of rapamycin (mTOR) signalling pathway is significantly associated with SIMD in an animal model; however, there have been ... and interferon-γ were examined.ResultsCompared with non-SIMD patients, patients with SIMD had higher ICU and 28-day mortality, PS6K ... LC3B levels. Serum PS6K levels in patients with SIMD were significantly negatively and positively correlated with LC3B ... at ICU admission could predict the incidence of SIMD with a sensitivity and specificity of 91.7% ...
Tópico(s): Cardiac Ischemia and Reperfusion
2019 - Elsevier BV | Canadian Journal of Cardiology
Amir Morad, Leonid Yavits, Ran Ginosar,
GP-SIMD, a novel hybrid general-purpose SIMD computer architecture, resolves the issue of data synchronization by in-memory computing through combining data storage and massively parallel processing. GP-SIMD employs a two-dimensional access memory with modified ... row. An analytic performance model of the GP-SIMD architecture is presented, comparing it to associative processor and to conventional SIMD architectures. Cycle-accurate simulation of four workloads supports ... analytical comparison. Assuming a moderate die area, GP-SIMD architecture outperforms both the associative processor and conventional ...
Tópico(s): Interconnection Networks and Systems
2015 - Association for Computing Machinery | ACM Transactions on Architecture and Code Optimization
Hiroshi Inoue, Moriyoshi Ohara, Kenjiro Taura,
... intersections with sorted arrays on modern processors with SIMD instructions and high branch misprediction penalties. Our algorithm efficiently exploits SIMD instructions and can drastically reduce branch mispredictions. Our ... can execute these comparisons more efficiently using the SIMD instructions and gain the benefits of the reduced ... with gcc by up to 5.2x using SIMD instructions and by up to 2.1x even without using SIMD instructions for 32-bit and 64-bit integer datasets. Our SIMD algorithm also outperformed an existing algorithm that can ...
Tópico(s): Advanced Database Systems and Queries
2014 - Association for Computing Machinery | Proceedings of the VLDB Endowment
Xiaoying Chen, Xian Liu, RuiAn Dong, Dan Zhang, Shu Qin,
... 8 in patients with sepsis-induced myocardial dysfunction (SIMD) and a reduced left ventricular ejection fraction (LVEF) ... 2017 to December 2020 were divided into a SIMD group (42 patients) and NO-SIMD group (214 patients). Diagnostic criteria of sepsis were based on SEPSIS 3.0 guidelines. SIMD was defined as LVEF <50% by echocardiography and ... RESULTS:Plasma levels of IL-8 in the SIMD group were significantly higher than those in the NO-SIMD group, 133.90 (80.20, 402.79) vs ... using this cut-off value, IL-8 predicted SIMD in sepsis with a sensitivity of 83.3% ...
Tópico(s): Respiratory Support and Mechanisms
2021 - International Scientific Information Inc. | Medical Science Monitor
Almudena Lindoso, M. García-Valderas, Luis Entrena, Yolanda Morilla, Pedro Martín-Holgado,
This work analyzes the suitability of SIMD (Single Instruction Multiple Data) extensions of current microprocessors under radiation environments.SIMD extensions are intended for software acceleration, focusing mostly in applications ... common in many fields such as computer vision.SIMD extensions use a dedicated coprocessor that makes possible ... high performance could benefit from the use of SIMD coprocessors, but their reliability needs to be studied.In this work NEON™, the SIMD coprocessor of ARM microprocessors, has been selected as ...
Tópico(s): Interconnection Networks and Systems
2018 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Nuclear Science
Xinhai Chen, Peizhen Xie, Lihua Chi, Jie Liu, Chunye Gong,
... units. In order to take full advantage of SIMD acceleration technology in SpMV, we proposed a new matrix storage format called CSR‐SIMD. The new storage format compresses the non‐zero ... be completely calculated by vectorized implementation on wide SIMD units. Our experimental results indicate that CSR‐SIMD has better storage efficiency and low‐overhead for ... the new format achieves high scalability on wide SIMD units. In comparison with the CSR‐based and BCSR‐based SpMV, CSR‐SIMD obtains better performance on FT1500A, Intel Xeon, and ...
Tópico(s): Distributed and Parallel Computing Systems
2018 - Wiley | Concurrency and Computation Practice and Experience
Aditi Jain, Jhuma Sankar, Anubhuti Anubhuti, Dinesh Kumar Yadav, M. Jeeva Sankar,
... prevalence and effects of sepsis-induced myocardial dysfunction (SIMD) in children with septic shock. Enrolled children with ... troponin-I (cTnI) estimation within first 3 h. SIMD was defined as presence of systolic/diastolic dysfunction by echocardiography. The prevalence of SIMD was 71% in 'septic shock' and 23% in ' ... prevalent than systolic dysfunction (32.3%). Children with SIMD had higher requirement of inotropes [81 vs. 44%; ... 62.5%) and specificity (55.1%) for detecting SIMD. On follow-up at 3 months, there was ...
Tópico(s): Heart Failure Treatment and Management
2017 - Oxford University Press | Journal of Tropical Pediatrics
Nigel P. Smart, Fréderik Vercauteren,
... scheme and mentioned that the scheme could support SIMD style operations. The slow key generation process of ... their key generation method appears to exclude the SIMD style operation alluded to by Smart and Vercauteren. ... show how to select parameters to enable such SIMD operations. As such, we obtain a somewhat homomorphic scheme supporting both SIMD operations and operations on large finite fields of ... data elements separately. However, we show that the SIMD operations can be used to perform the recrypt ...
Tópico(s): Ferroelectric and Negative Capacitance Devices
2012 - Springer Nature | Designs Codes and Cryptography