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Graham Ward, David Frenk Executive director, Miriam Gaceri Kinyua, Paul King Chief executive, Anshul Rai, Pierre J. L. Lagoda Head of plant breeding and genetics, Michael Masters Chief executive, Sir Richard Branson Founder, Paul Waldenmeyer, Jerry Autry,

... Thinking outside the box Spain's cajas Microfight SKS comes to market Buttonwood Paying the price Out ...

2010 - Gale Group | The Economist

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Artigo Acesso aberto Revisado por pares

G. W. A. Dick,

... Mengo virus is serologically closely related to Col. SK, M.M. and EMC viruses, (b) Mengo and Col. SK viruses bear no antigenic relationship to the Lansing, Yale-SK (from Yale laboratory) or MEF-1 strains of ... small laboratory animals by Mengo, EMC and Col. SK viruses, and (f) the Col. SK and M.M. strains of virus are serologically identical. (The similarity of Col. SK and M.M. viruses has already been reported ... and this observation has been confirmed.) Since Col. SK virus bears no antigenic relationship to any of ...

Tópico(s): Plant Virus Research Studies

1949 - American Association of Immunologists | The Journal of Immunology

Artigo Acesso aberto Revisado por pares

Charles F. Dunkl,

... all rotations on certain spaces of functions on Sk, the /¿-dimensional sphere (k^2), namely C, L1, ... of various spaces of functions and measures on Sk, which involves the ultraspherical polynomials.Notation.Sk admits a group of rotations, namely the special ... defined by RJ(x) = /(*«) for all x e Sk, Rap(E) = n(Ea) for all /¿-measurable subsets E of Sk.P% is the ultraspherical polynomial of index A and degree n (normalized by ^nO)=l)-Considering Sk imbedded as the unit sphere in Rk + 1, ... points x and y (-1 ^x-y¿ 1).Sk has a unique rotation invariant Borel measure, say ...

Tópico(s): Algebraic and Geometric Analysis

1966 - American Mathematical Society | Transactions of the American Mathematical Society

Artigo Acesso aberto Revisado por pares

Charles F. Dunkl,

... all rotations on certain spaces of functions on Sk, the /¿-dimensional sphere (k^2), namely C, L1, ... of various spaces of functions and measures on Sk, which involves the ultraspherical polynomials.Notation.Sk admits a group of rotations, namely the special ... defined by RJ(x) = /(*«) for all x e Sk, Rap(E) = n(Ea) for all /¿-measurable subsets E of Sk.P% is the ultraspherical polynomial of index A and degree n (normalized by ^nO)=l)-Considering Sk imbedded as the unit sphere in Rk + 1, ... points x and y (-1 ^x-y¿ 1).Sk has a unique rotation invariant Borel measure, say ...

Tópico(s): Algebraic and Geometric Analysis

1966 - American Mathematical Society | Transactions of the American Mathematical Society

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Artigo Acesso aberto Revisado por pares

Chester M. Southam, Joseph H. Burchenal, Bayard D. Clarkson, Adrienne Tanzi, Rosemary Mackey, Vivian McComb,

... Raji, SL-1) one from reticulum cell sarcoma (SK-RCS1), 6 from leukemia (SK-L2 SK-L4, SK-L6, SK-L7, SK-L9, SK-L10), one from a normal lymph node (SK-LN1), and one from infectious mononucleosis (C566). Fourteen ... 2 and EB 3 from Burkitt tumors, lines SK-L2 and SK-L4 from acute leukemia, and the 2 lines ...

Tópico(s): Cytomegalovirus and herpesvirus research

1969 - Wiley | Cancer

Artigo Acesso aberto Revisado por pares

Gerald E. Siefring, Francis Castellino,

... they possess molecular weights of approximately 40,000 (SK 1), 36,000 (SK 2), 31,000 (SK 3), 26,000 (SK 4), and 10,000 (SK 5) under denaturing conditions, as observed on calibrated ... plasminogen employed. Utilizing rabbit plasminogen and streptokinase, the SK 4 fragment was purified. This fragment arises by ... However, when isolated utilizing dilute aqueous buffers, the SK 4 fragment contained a portion of the original ... of native streptokinase noncovalently bound to the molecule (SK 4'). SK 4' is capable of activating human ...

Tópico(s): Peptidase Inhibition and Analysis

1976 - Elsevier BV | Journal of Biological Chemistry

Artigo Revisado por pares

Robert G. Pendleton, George Gessner, John L. Sawyer,

After 7 day dosing with SK & F 64139, an inhibitor of adrenal and CNS PNMT, a stoichiometric relationship is observed between epinephrine decrease and norepinephrine increase in ... is not found with the adrenal PNMT inhibitor, SK & F 29661. SK & F 64139 was found to possess significant adrenal MAO inhibitory activity, but SK & F 29661 does not. Three factors are presented ... profile difference. We then performed various studies with SK & F 29661 and 64139 to examine whether enzymes ... not. However. when rats were dosed with either SK & F 29661 or 64139 over 24 h and ...

Tópico(s): Receptor Mechanisms and Signaling

1980 - Elsevier BV | European Journal of Pharmacology

Artigo Revisado por pares

Akikazu Takada, Kota Mochizuki, Yumiko Takada,

... to the mixture of plasminogen and streptokinase (called SK-activator activity) resulted in decreased extent of hydrolysis ... TAMe (tosyl arginine methyl ester). The addition of SK-potentiator to the mixture of SK (streptokinase), plasminogen and tranexamic acid prevented the decrease in SK-activator activity caused by tranexamic acid, thus SK-potentiator counteracting with the effects of tranexamic acid. Fibrinogen potentiated SK-activator activity, but did not prevent the decrease ... activity caused by tranexamic acid. Fibrinogen added to SK and plasminogen prior to tranexamic acid prevented the ...

Tópico(s): Blood properties and coagulation

1980 - Elsevier BV | Thrombosis Research

Artigo Acesso aberto Revisado por pares

R Hahn, Joe R. Wardell,

The renal vasodilator activity of SK&F 38393 and dopamine have been compared in anesthetized dogs surgically prepared with arterial blood pressure catheters and renal artery blood flowprobes. Intravenous infusion of SK&F 38393 (10–2,430 μg/kg/min) ... Maximum decreases in renal vascular resistance produced by SK&F 38393 and dopamine were 19 ± 4 and ... 25 ± 7%) and cardiac rate (52 ± 7%), while SK&F 38393 produced only an increase in pressure (17 ± 4%). The relative lack of efficacy of SK&F 38393 on alpha- and beta-adrenergic receptors ...

Tópico(s): Blood Pressure and Hypertension Studies

1980 - Lippincott Williams & Wilkins | Journal of Cardiovascular Pharmacology

Artigo Acesso aberto Revisado por pares

Namboori B. Raju,

ABSTRACT Crosses heterozygous and homozygous for Sk–1, Sk–2 and Sk–3 were examined by light microscopy. All three Spore killers behave similarly. In heterozygoua killer x sensitive ... only after killer and sensitive alleles, SkK and SkS, have segregated into separate ascospores. Homozygous killer x ... the degenerating sensitive ascospores in heterozygous asci.——With Sk–2, it was shown that SkS nuclei do not abort when both SkK and SkS are present in the same ascospore. Mutants affecting ... to obtain large ascospores enclosing both SkK and SkS meiotic products in a common cytoplasm. SkS nuclei ...

Tópico(s): Plant Reproductive Biology

1979 - Oxford University Press | Genetics

Artigo Acesso aberto Revisado por pares

Barbara C. Turner, David D. Perkins,

ABSTRACT Three chromosomal factors called Spore killer (Sk) have been found in wild populations of Neurospora sitophila and N . intermedia. Sk resembles other examples of meiotic drive such as Segregation Distorter ... Gamete eliminator in tomato. In crosses heterozygous for Sk, each ascus contains four viable black ascospores and ... When crosses are homozygous for an allele of Sk, all eight ascospores are viable and black in ... not found in any of the asci of Sk-homozygous crosses.)—killer (Sk-1K) and sensitive (Sk- ...

Tópico(s): Plant Disease Resistance and Genetics

1979 - Oxford University Press | Genetics

Artigo Acesso aberto Revisado por pares

Richard S. Meltzer, Marcel van den Brand, Patrick W. Serruys, P. Fioretti, Paul G. Hugenholtz,

... AMI) treated with direct intracoronary infusion of streptokinase (SK) followed by emergency coronary artery bypass grafting (CABG). ... underwent emergency coronary artery angiography with infusion of SK. Thirty-four of these patients with partial restoration ... management of resuscitation of patients with AMI, (2) SK-induced coagulopathy and ongoing thrombolysis, and (3) timely ... to preserve myocardial salvage. To highlight comparisons of SK-CABG management, data regarding 34 consecutive patients having routine non—SK-CABG surgery were collected simultaneously during the study. ...

Tópico(s): Coronary Interventions and Diagnostics

1982 - Elsevier BV | American Heart Journal

Artigo Revisado por pares

P. C. Sivelle, Anthony H. Underwood, J.A. Jelly,

... antiandrogenic activity whereas the other H2 receptor antagonists SK&F 92456, SK&F 92994, SK&F 92629 amd SK&F 93479 did not Cimetidine, metiamide and SK&F 92456 inhibited (3H] DHT binding to rat ventral prostate androgen receptor in vitro whereas SK&F 92629 and SK&F 93479 did not. SK&F 92994 affects DHT binding only slightly. Of ... H2 receptor antagonists only metiamide was antiandrogenic. However SK&F 92994 and SK&F 93479 are not antiandrogenic despite being more ...

Tópico(s): Hormonal and reproductive studies

1982 - Elsevier BV | Biochemical Pharmacology

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Akikazu Takada, Kota Mochizuki, Yumiko Takada,

... degradation products (FgDP-5′) enhanced the activity of SK-activator (SK-plasminogen or SK-plasmin) to the largest extent, and further degradation, ... chain (FgDP-20′), resulted in less enhancement of SK-activator activity than fibrinogen itself which also enhanced ... Fibrin enhanced the activation rate of plasminogen by SK to the largest extent, more than SK-potentiator. The action of thrombin on SK-potentiator was as effective as fibrin in the enhancement, thus removal of fibrinopeptides from fibrinogen or SK-potentiator is important in the activator activity of ...

Tópico(s): Platelet Disorders and Treatments

1981 - Elsevier BV | Thrombosis Research

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P. Rentrop, H. Blanke, K. R. Karsch, Wolfgang Rutsch, M Schartl, W. Merx, R. Dörr, D Mathey, Karl‐Heinz Kück,

... acute myocardial infarction (AMI) treated by intracoronary streptokinase (SK) infusion. Ejection fraction (EF) increased slightly, from 52% ± 13% before admission SK intervention to 58% ± 13% immediately after early recanalization ... AMI (2 to 4 weeks after successful early SK reperfusion) patients, repeat anglography revealed late reocclusion of ... Chronic EF was not significantly different from pre-SK intervontion EF in these nine patients with late ... patency, EF increased mildly from 52% ± 13% (before SK intervention) to 56% ± 16% (in long-term recanalization) ( ...

Tópico(s): Cardiovascular Function and Risk Factors

1981 - Elsevier BV | American Heart Journal

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