Beatriz Gimeno, Sara Martínez-Casasnovas, Inmaculada Velasco, Sofı́a T. Blanco, Javier Fernández,
In this work, density, vapor-liquid equilibrium and speed of sound measurements of the mixtures [CO2 + 4.72 mol% SO2 + 1.85 mol% CH4] and [CO2 + 0.09 mol% SO2 + 1.54 mol% CH4] were performed over the temperature range 263–373 K and at pressures of up to 30 MPa for density and up to 190 MPa for speed of sound. For the speed of sound measurements, the mixtures were doped with ≅0.8 mol% CH3OH. We compared our results to the values calculated using an extended version of the equation of state for combustion gases ( ...
Tópico(s): Chemical Thermodynamics and Molecular Structure
2019 - Elsevier BV | Fuel
Isabel Aguilar‐Palacio, María José Rabanaque, Lina Maldonado, Armando Chaure-Pardos, José María Abad-Díez, Montse León-Latre, José A. Casasnovas, Sara Malo,
The objective of this study was to analyse persistence to lipid-lowering drug use for primary prevention of cardiovascular disease (CVD) in a new users cohort, to explore all-cause and cardiovascular related morbidity, comorbidity and mortality in this group and, finally, to study the relationship between persistence and morbimortality. We selected subjects who started lipid-lowering treatment for primary prevention of CVD between 1 January 2010 and 31 December 2017 (N = 1424), and classified them as ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
2020 - Multidisciplinary Digital Publishing Institute | International Journal of Environmental Research and Public Health
... un considerable bagaje dramatico en su Galicia natal, Sara Casasnovas (Orense, 1984) afronta ahora, cargada de ilusion, el ...
Tópico(s): Spanish Culture and Identity
2010 - | Cambio 16
Carlos Casasnovas, Montserrat Ruíz, Agatha Schlüter, Alba Naudí, Stéphane Fourcade, M. Heras, Sara Castañer, Antonia Albertí, Núria Bargalló, Maria R. Johnson, Gerald V. Raymond, Ali Fatemi, Ann B. Moser, Francesc Villarroya, Manuel Portero‐Otín, Rafael Artuch, Reinald Pamplona, Aurora Pujol,
X-Adrenoleukodystrophy (X-ALD) and its adult-onset, most prevalent variant adrenomyeloneuropathy (AMN) are caused by mutations in the peroxisomal transporter of the very long-chain fatty acid ABCD1. AMN patients classically present spastic paraparesis that can progress over decades, and a satisfactory treatment is currently lacking. Oxidative stress is an early culprit in X-ALD pathogenesis. A combination of antioxidants halts the clinical progression and axonal damage in a murine model of AMN, providing ...
Tópico(s): Fuel Cells and Related Materials
2019 - Springer Science+Business Media | Neurotherapeutics
Belén Moreno‐Franco, Alejandro Pérez‐Esteban, Fernando Civeira, Pilar Guallar‐Castillón, José A. Casasnovas, Rocío Mateo‐Gállego, Estíbaliz Jarauta, Sara Malo, Martín Laclaustra,
Many addictive substances, such as tobacco and alcohol, influence atherosclerosis development. Whether or not tobacco's pro-atherosclerotic effect is influenced by alcohol consumption is unknown. We aimed to estimate the impact of alcohol intake on the presence of subclinical atherosclerosis in femoral arteries in smoking and non-smoking middle-aged men.Cross-sectional analysis of a subset of the Aragon Workers Health Study (AWHS), comprising 2099 men with mean age 50.9 years without previous cardiovascular ...
Tópico(s): Liver Disease Diagnosis and Treatment
2020 - Wiley | Addiction
Armando Chaure-Pardos, Isabel Aguilar‐Palacio, María José Rabanaque, María Jesús Lallana, Lina Maldonado, Sara Castel-Feced, Julián Librero, José A. Casasnovas, Sara Malo,
In this study, we analyzed the effectiveness of statin therapy for the primary prevention of cardiovascular disease (CVD) in low- and medium-risk patients. Using observational data, we estimated effectiveness by emulating a hypothetical randomized clinical trial comparing statin initiators with statin non-initiators. Two approaches were used to adjust for potential confounding factors: matching and inverse probability weighting in marginal structural models. The estimates of effectiveness were obtained ...
Tópico(s): Diabetes, Cardiovascular Risks, and Lipoproteins
2022 - Multidisciplinary Digital Publishing Institute | Journal of Personalized Medicine
Mercé Falip, L. Rodríguez-Bel, Sara Castañer, Jacint Sala‐Padró, Júlia Miró, Sònia Jaraba, Carlos Casasnovas, Francisco Morandeira, Javier Berdejo, Mar Carreño,
Background: Antibodies to glutamic acid decarboxylase (GAD ab) have been found in patients with limbic encephalitis (LE) and chronic pharmacoresistant focal epilepsy (FE). The objectives of the study were to: (1) analyze the clinical and neuroimaging course of patients with FE+GAD ab, (2) compare these characteristics with a control group, and (3) describe the most affected cerebral areas with structural and functional imaging. Methods: Patients with FE + high titers of GAD ab and a follow-up of at least ...
Tópico(s): Genetic Neurodegenerative Diseases
2019 - Frontiers Media | Frontiers in Neurology
Isabel Aguilar‐Palacio, Sara Malo, Cristina Feja, MaJesús Lallana, Montserrat León-Latre, José A. Casasnovas, María José Rabanaque, Eliseo Güallar,
Benefits of cardiovascular disease (CVD) risk factors control are well known, but goals achievement remains low. The objective of this study is to evaluate the prevalence of CVD risk factors among men ina worker’s cohort with no previous CVD, to study control variations across time and the factors associated with poor control. To this end, we conducted a cohort reexamination (2010–2014) within the context of the Aragon Workers Health Study (AWHS). Data from working characteristics, analytical values ...
Tópico(s): Workplace Health and Well-being
2018 - Public Library of Science | PLoS ONE
Patricia Pérez, David Astorgano, Guillermo Albericio, Sara Flores, Pedro J. Sánchez‐Cordón, Joanna Luczkowiak, Rafaël Delgado, José M. Casasnovas, Mariano Estéban, Juan García‐Arriaza,
Current coronavirus disease-19 (COVID-19) vaccines are administered by the intramuscular route, but this vaccine administration failed to prevent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus infection in the upper respiratory tract, mainly due to the absence of virus-specific mucosal immune responses. It is hypothesized that intranasal (IN) vaccination could induce both mucosal and systemic immune responses that blocked SARS-CoV-2 transmission and COVID-19 progression. Here, we ...
Tópico(s): Bacterial Infections and Vaccines
2022 - Frontiers Media | Frontiers in Immunology
Vera Bril, Artur Drużdż, Julian Großkreutz, Ali A. Habib, Renato Mantegazza, Sabrina Sacconi, Kimiaki Utsugisawa, John Vissing, Tuan Vu, Marion Boehnlein, Ali Bozorg, Maryam Gayfieva, Bernhard Greve, Franz Woltering, Henry J. Kaminski, Angela Genge, Rami Massie, Maxime D. Bérubé, Vera Bril, Lubna Daniyal, Shabber Mannan, Eduardo Ng, Ritesh Rohan Raghu Raman, Evelyn Sarpong, Mónica Alcántara, Annie Dionne, Zaeem A. Siddiqi, Derrick Blackmore, Faraz Hussain, Geneviève Matte, Stéphan A. Botez, Michaela Týblová, Michala Jakubíková, Jana Junkerová, John Vissing, Nanna Witting, Sonja Holm‐Yildiz, Mads Stemmerik, Henning Andersen, Izabella Obál, Guilhem Solé, Stéphane Mathis, Marie‐Hélène Violleau, Christine Tranchant, Sihame Messai, Jean‐Baptiste Chanson, Aleksandra Nadaj‐Pakleza, Arnaud Verloes, Leila Zaidi, Sabrina Sacconi, Manuela Gambella, Michele Cavalli, Tanya Stojkovic, Sophie Demeret, Loïc Le Guennec, Giorgia Querin, Nicolas Weiss, Marion Masingue, Laurent Magy, Karima Ghorab, Ia Rukhadze, Alexander Tsiskaridze, Marina Janelidze, Temur Margania, Florian Then Bergh, Eike Hänsel, Andrea Kalb, Bianca Meilick, Mandy Reuschel, Lars-Malte Teußer, Astrid Unterlauft, Clemens Goedel, Tim Hagenacker, Andreas Totzeck, Benjamin Stolte, Franz Blaes, Christine Bindler, Vasilios Tsoutsikas, Annekathrin Roediger, Christian Geis, Jens Schmidt, Jana Zschüntzsch, Margret Schwarz, Stefanie Meyer, Karsten Kummer, Stefanie Glaubitz, Rachel Zeng, Heinz Wiendl, Luisa Klotz, Anna Lammerskitten, Jan D. Lünemann, Péter Diószeghy, Renato Mantegazza, Lorenzo Maggi, Elena Rinaldi, Matteo Gastaldi, Federico Mazzacane, Pietro Businaro, Raffaele Iorio, Giovanni Antonini, Laura Fionda, Rita Rinaldi, Símone Rossi, Francesco Habetswallner, Francesco Tuccillo, Haruna Umehara, Eiko Uenaka, Masanori Takahashi, Keiko Higashi, Makoto Kinoshita, Emika Yoneda, Noriko Nakamura, Saeka Fujita, Tomoya Kubota, Masami Ono, Sana Yamamoto, Taku Hatano, Kazuki Oikoshi, Kazumasa Yokoyama, Yutaka Oji, Yuji Tomizawa, Akiyuki Uzawa, Manato Yasuda, Sachiko Akita, Yukiko Ozawa, Yosuke Onishi, Miki Takaki, Hiromi Yamada, Kanako Minemoto, Miki Sanko, Nanae Izawa, Mayumi Nakayama, Masayuki Masuda, Rune Tsuji, Nobuhiro Ido, Yumi Hyodo, Yoshihiko Okubo, Akiko Minohara, Nana Haraguchi, Makiko Naito, Seiko Yoshida, Yuri Fukushige, Akira Tsujino, Atsushi Nagaoka, Teiichiro Miyazaki, Shunsuke Yoshimura, Takuro Hirayama, Tomoaki Shima, Naoko Okamoto, Riki Matsumoto, Kenji Sekiguchi, Takehiro Ueda, Norio Chihara, Mari Kirimura, Emi Sunagawa, Ayaka Suzuki, Shigeaki Suzuki, Aozora Wada, Kei Ishizuchi, Yasushi Suzuki, Mitsuo Yata, Yuka Komatsu, Kenichi Tsukita, Genya Watanabe, Kazuki Sato, Emiko Kawasaki, Naoki Yamamoto, Hirohiko Ono, Tomoko Tsuda, Shigeki Ohashi, Kimiaki Utsugisawa, Yuka Fujisawa, Yumiko Yokota, Yuriko Nagane, Kameda Ayumi, Yuka Takematsu, Hiroyuki Naito, Takamichi Sugimoto, Kumiko Kuwada, Konrad Rejdak, Sebastian Szklener, Monika Kitowska, Kandyda Derkacz, Artur Drużdż, Tomasz Berkowicz, Paulina Budzinska, Marek Halas, Leonid Zaslavskiy, Evgeniya Skornyakova, Sergey Kotov, Ekaterina Novikova, Ольга Григорьевна Сидорова, Vitalii Goldobin, T. V. Alekseeva, P. Sh. Isabekova, Nadezhda Malkova, D. S. Korobko, Gordana Djordjević, Aleksandar Stojanov, Stojan Perić, Dragana Lavrnić, Ivo Božović, Aleksa Palibrk, Carlos Casasnovas, Velina Nedkova-Hristova, Nuria Vidal Fernández, Elena Cortés Vicente, Luis Querol Gutiérrez, Maria Salvadó Figueras, Anna Canovas Segura, Raúl Juntas Morales, Daniel Sanchez Tejerina, Albert Saiz, Yolanda Blanco Morgado, Sara Llufriú Durán, María Sepúlveda Gázquez, Eugenia María Martínez Hernández, Gerardo Gutiérrez‐Gutiérrez, Paqui Iniesta, José Meca Lallana, Yuh‐Cherng Guo, Hou‐Chang Chiu, Jiann‐Horng Yeh, Ya Hui Chen, M Lee, Yi‐Chung Lee, Kuan Lin Lai, Said R. Beydoun, Salma Akhter, Tuan H. Vu, Lucy Lam, Alisha Thomas, Michael H. Rivner, Brandy Quarles, Dale J. Lange, Shara Holzberg, Pantelis Pavlakis, Ashwathy Goutham, Henry J. Kaminski, Radwa Aly, Lisa Ashworth, Kathryn E. Bender, Karie Bond, Joanne Buckner, Sara Byerly, James B. Caress, Jessyca Clemons, Asha Farmer, Catherine Franklin, Summer Harris, Meredith Hiatt, Rachana Gandhi, G Miller, Lynn Smith, Rose Marie Smith, Brian Strittmatter, Tahseen Mozaffar, Ali A. Habib, Isela Hernandez, Kelsey Moulton, Chafic Karam, Pranali Ravikumar, Catherine Lomen‐Hoerth, Laura Rosow, Hannah George, Viktoriya Irodenko, Min Su Kang, Carol Denny, Bart Hanson, S. Klein, Jennifer M. Martinez‐Thompson, Elie Naddaf, Denny Padgett, Eric J. Sorenson, Jane L. Sultze, Delena Weis, Kourosh Rezania, Jason R. Thonhoff, Sheetal Shroff, Robert M. Pascuzzi, Angela Micheels, Cynthia Bodkin, Adam Comer, Gelasio Baras, R.M. Wagner, Zabeen Mahuwala, Stephen J. Ryan, Kai Su, Khema R. Sharma, Andrew Brown, Kore Liow,
Generalised myasthenia gravis is a chronic, unpredictable, and debilitating autoimmune disease. New treatments for this disease are needed because conventional therapies have limitations, such as side-effects (eg, increased infection risk) or inadequate control of symptoms. Rozanolixizumab is a neonatal Fc receptor blocker that might provide a novel therapeutic option for myasthenia gravis. We aimed to assess the safety and efficacy of rozanolixizumab for generalised myasthenia gravis.MycarinG is ...
Elsevier BV
Mercé Falip, Sònia Jaraba, L. Rodríguez-Bel, Sara Castañer, Jaume Mora, Pablo Arroyo, Júlia Miró, Jacint Sala‐Padró, Sergio Martínez‐Yélamos, Carlos Casasnovas, Jordi Gascón‐Bayarri, Eva Real, Francisco Morandeira, Noemí Vidal, M. Heras, Albert Saiz, Mar Carreño,
ObjectiveTo follow prospectively a group of patients with seizures or epilepsy and suggestive clinical features of autoimmune aetiology and find out how many are finally diagnosed with acute symptomatic seizures (ASS) secondary to autoimmune encephalitis or autoimmune-related epilepsy, and how many develop epilepsy.MethodsConsecutive patients meeting the inclusion criteria from 2010 to 2018 were identified. Patients were classified as confirmed, probable autoimmune, non-autoimmune, or unknown.ResultsOne- ...
Tópico(s): Epilepsy research and treatment
2020 - Elsevier BV | Seizure
Arielle F. Casasnovas, Kathryn M. Huryk, Devorah Levinson, Sara Markowitz, Shoshana Friedman, Eric Stice, Katharine L. Loeb,
The Body Project (BP) is a cognitive dissonance-based eating disorders (ED) prevention program that targets thin-ideal internalization and reduces ED risk factors and onset for higher-risk adolescent/young adult females. Although the more insular Orthodox Jewish communities reduce exposure to mainstream secular media, they are not immune to thin-ideal internalization and EDs. The present uncontrolled study evaluated the preliminary effects of a cultural adaptation of the BP for Orthodox Jewish girls. ...
Tópico(s): Obesity and Health Practices
2019 - Taylor & Francis | Eating Disorders
Sara Malo, Isabel Aguilar‐Palacio, Cristina Feja, Enrica Menditto, María Jesús Lallana, Elena Andrade-Gómez, José A. Casasnovas, María José Rabanaque,
The aim of this study was to assess patterns of treatment persistence in a cohort of male Spanish workers receiving statin therapy for primary prevention of cardiovascular disease. This descriptive study was conducted within the framework of the prospective longitudinal Aragon Workers' Health Study (N = 5400). Incident male statin users were identified based on data collected from the regional government's medication consumption information system. Patterns of treatment persistence with statins prescribed ...
Tópico(s): Antiplatelet Therapy and Cardiovascular Diseases
2017 - Elsevier BV | Revista Española de Cardiología (English Edition)
Sara Malo, Isabel Aguilar‐Palacio, Cristina Feja, Enrica Menditto, María Jesús Lallana, Elena Andrade-Gómez, José A. Casasnovas, María José Rabanaque,
El objetivo de este estudio es analizar el patrón de persistencia con estatinas en prevención primaria de enfermedad cardiovascular en una cohorte de trabajadores españoles. Este estudio descriptivo se llevó a cabo en el marco del estudio prospectivo longitudinal Aragon Workers’ Health Study (n = 5.400). Se identificó a los nuevos usuarios de estatinas varones a partir de datos recogidos en el sistema de información de consumo farmacéutico de Aragón. Se analizaron los patrones de persistencia con estatinas ...
Tópico(s): Acute Myocardial Infarction Research
2017 - Elsevier BV | Revista Española de Cardiología
Patricia Pérez, Guillermo Albericio, David Astorgano, Sara Flores, Cristina Sánchez-Corzo, Pedro J. Sánchez‐Cordón, Joanna Luczkowiak, Rafaël Delgado, José M. Casasnovas, Mariano Estéban, Juan García‐Arriaza,
The constant appearance of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VoCs) has jeopardized the protective capacity of approved vaccines against coronavirus disease-19 (COVID-19). For this reason, the generation of new vaccine candidates adapted to the emerging VoCs is of special importance. Here, we developed an optimized COVID-19 vaccine candidate using the modified vaccinia virus Ankara (MVA) vector to express a full-length prefusion-stabilized SARS-CoV- ...
Tópico(s): vaccines and immunoinformatics approaches
2023 - Frontiers Media | Frontiers in Immunology
Erola Pairo‐Castineira, Konrad Rawlik, Andrew D. Bretherick, Ting Qi, Yang Wu, Isar Nassiri, Glenn A. McConkey, Marie Zechner, Lucija Klarić, Fiona Griffiths, Wilna Oosthuyzen, Athanasios Kousathanas, Anne Richmond, Jonathan Millar, Clark D Russell, Tomas Malinauskas, Ryan S. Thwaites, Kirstie Morrice, Seán Keating, David M. Maslove, Alistair Nichol, Malcolm G. Semple, Julian C. Knight, Manu Shankar‐Hari, Charlotte Summers, Charles Hinds, Peter Horby, Lowell Ling, Daniel F. McAuley, Hugh Montgomery, Peter Openshaw, Colin B. Begg, Timothy Walsh, Albert Tenesa, Carlos Flores, José A. Riancho, Augusto Rojas‐Martínez, Pablo Lapunzina, Sara Clohisey, Johnny Millar, Manu Shankar‐Hari, Emma Aitkin, Latha Aravindan, Ruth Armstrong, J. Kenneth Baillie, Heather Biggs, Ceilia Boz, Adam Brown, Primmy Chikowore, Richard Clark, Audrey Coutts, J. Terrence Coyle, Louise Cullum, Sukamal Das, Nicky Day, Lorna Donnelly, Esther Duncan, Paul Finernan, Max Head Fourman, Anita Furlong, James Furniss, Bernadette Gallagher, Tammy Gilchrist, Ailsa Golightly, Fiona Griffiths, Katarzyna Hafezi, Debbie Hamilton, Ross Hendry, Naomi Kearns, Dawn Law, R. M. Law, Sarah Law, Rebecca Lidstone-Scott, Christen Lauder, Louise MacGillivray, Alan Maclean, Hanning Mal, Sarah McCafferty, Ellie Mcmaster, Jen Meikle, Shona C. Moore, Sheena Murphy, Hellen Mybaya, Miranda Odam, Wilna Oosthuyzen, Chenqing Zheng, Jiantao Chen, Nick Parkinson, Trevor Paterson, Petra Tucker, Katherine Schon, Andrew Stenhouse, Mihaela Das, Maaike Swets, Helen Szoor-McElhinney, Filip Taneski, Lance Turtle, Tony Wackett, Mairi Ward, Jane Weaver, Nicola Wrobel, Marie Zechner, Jacqueline Pan, Neus Grau, Tim Jones, Rosario Lim, Martina Marotti, R. Chris Whitton, Aneta Bociek, Sara Campos, Gill Arbane, Manu Shankar‐Hari, Marlies Ostermann, Mina Cha, Fabiola DAmato, Eirini Kosifidou, Shelley Lorah, Kyma Morera, Sarah Bircham, Laura Brady, Keith Hugill, Jeremy Henning, Stephen Bonner, Evie Headlam, Jessica Jones, A. List, J Morley, Amy Welford, Bobette Kamangu, Anitha Ratnakumar, Abiola Shoremekun, Zoe Alldis, Raine Astin-Chamberlain, Fatima Bibi, Jack Biddle, Sarah Blow, Matthew L. Bolton, Catherine Borra, Ruth Bowles, Maudrian Burton, Yasmin Choudhury, Amber Cox, Amy Easthope, Patrizia Ebano, Stavros Fotiadis, Jana Gurasashvili, Rosslyn Halls, Pippa Hartridge, Delordson Kallon, Jamila Kassam, Ivone Lancoma-Malcolm, Maninderpal Matharu, P. May, Oliver Mitchelmore, Tabitha Newman, Mital Patel, Jane Pheby, Irene Pinzuti, Zoe Prime, Oleksandra Prysyazhna, Julian Shiel, Melanie Taylor, Carey Tierney, Olivier Zongo, S. M. Wood, Anne Zak, David Collier, Manuela Mundy, C. C. Thompson, Lisa Pritchard, Minnie Gellamucho, David Cartlidge, Nageswar Bandla, Lucy Bailey, Michelle Davies, Jane Delaney, Leanne Scott, Marwa Abdelrazik, Frater Alasdair, David Carter, Munzir Elhassan, Arunkumar Ganesan, Samuel Jenkins, Zoe Lamond, Dharam Purohit, Kumar Rohit, Malik Saleem, Alanna Wall, Kugan Xavier, Dhanalaksmi Bakthavatsalam, Kirolos Gehad, Pakeerathan Gnanapragasam, Kapil Jain, Swati Jain, Abdul Malik, Naveen Pappachan, Jerónimo Moreno-Cuesta, Anne Haldeos, Rachel Vincent, Maryjane Oziegb, Anna Cavazza, Maeve Cockrell, Eleanor Corcoran, Maria Depante, Clare Finney, Ellen Jerome, Abigail Knighton, Monalisa Nayak, Evita Pappa, Rohit Saha, Sian Saha, Andrew Dodd, Kevin O’Reilly, Mark McPhail, Emma Clarey, Harriet Noble, John Smith, Phoebe Coghlan, Stephen J. Brett, Anthony Gordon, Maie Templeton, David Antcliffe, Dorota Banach, Sarah Darnell, Ziortza Fernandez, Eleanor Jepson, Amal Mohammed, Roceld Rojo, Sonia Sousa Arias, Anita Gurung, Jenny Wong, Jaime Fernandez-Roman, David Hamilton, Emily Johnson, Brian Johnston, Maria Lopez Martinez, Suleman Mulla, Alicia Waite, Karen Williams, Victoria Waugh, Ingeborg Welters, Jessica Emblem, Maria Norris, David Shaw, Archana Bashyal, Sally Beer, Paula Hutton, Stuart McKechnie, Neil Davidson, Soya Mathew, Grace Readion, Jung Hee Ryu, Jean Wilson, Shruti Agrawal, Kay Elston, Megan Jones, Eoghan Meaney, Petra Polgarova, Muhammad Elbehery, Charlotte Summers, Esther Daubney, Anthony Ng, Jocelyn R. Marshall, Nazima Pathan, Katerina Stroud, Deborah White, Angela Andrew, Saima Ashraf, Amy Clark, Martin Dent, Margaret Langley, Cecilia Peters, Lucy Ryan, Julia Sampson, Shuying Wei, Alice Baddeley, Megan Meredith, Lucy Morris, Alexandra Gibbons, Lisa McLoughlin, Carlos Castro Delgado, Victoria Clark, Deborah Dawson, Lijun Ding, Georgia Durrant, Obiageri Ezeobu, Abiola Harrison, William James Hurt, Rebecca Kanu, Ashley Kinch, Susannah Leaver, Ana Lisboa, Jisha Mathew, Kamal Patel, Romina Pepermans Saluzzio, John Rawlins,
Critical illness in COVID-19 is an extreme and clinically homogeneous disease phenotype that we have previously shown
Nature Portfolio
Daniela Matuozzo, Estelle Talouarn, Astrid Marchal, Peng Zhang, Jérémy Manry, Yoann Seeleuthner, Yu Zhang, Alexandre Bolze, Matthieu Chaldebas, Baptiste Milisavljevic, Adrian Gervais, Paul Bastard, Takaki Asano, Lucy Bizien, Federica Barzaghi, Hassan Abolhassani, Ahmad Abou Tayoun, Alessandro Aiuti, Ilad Alavi Darazam, Luis M. Allende, Rebeca Alonso‐Arias, Andrés A. Arias, Gökhan Aytekіn, Peter Bergman, Simone Bondesan, Yenan T. Bryceson, Ingrid G. Bustos, Óscar Cabrera-Marante, Sheila Cárcel, Paola Carrera, Giorgio Casari, Khalil Chaïbi, Roger Colobrán, Antônio Condino‐Neto, Laura Covill, Ottavia M. Delmonte, Loubna El Zein, Carlos Flores, Peter K. Gregersen, Marta Gut, Filomeen Haerynck, Rabih Halwani, Selda Hançerli, Lennart Hammarström, Nevin Hatipoğlu, Adem Karbuz, Sevgi Keleş, Christèle Kyheng, Rafael León‐López, José Luis Franco, Davood Mansouri, Javier Martínez‐Picado, Özge Metin Akcan, Isabelle Migeotte, Pierre‐Emmanuel Morange, Guillaume Morelle, Andrea Martín-Nalda, Giuseppe Novelli, Antonio Novelli, Tayfun Özçelık, Figen Palabıyık, Qiang Pan‐Hammarström, Rebeca Pérez de Diego, Laura Planas‐Serra, Daniel E. Pleguezuelo, Carolina Prando, Aurora Pujol, Luis Felipe Reyes, Jacques G. Rivière, Carlos Rodríguez‐Gallego, Julián Rojas, Patrizia Rovere‐Querini, Agatha Schlüter, Mohammad Shahrooei, Ali Sobh, Pere Soler‐Palacín, Yacine Tandjaoui-Lambiotte, Imran Tipu, Cristina Tresoldi, Jesús Troya, Diederik van de Beek, Mayana Zatz, Paweł Zawadzki, Saleh Zaid Al-Muhsen, Mohammed F. Alosaimi, Fahad Alsohime, Hagit Baris Feldman, Manish J. Butte, Stefan N. Constantinescu, Megan A. Cooper, Clifton L. Dalgard, Jacques Fellay, James R. Heath, YL Lau, Richard P. Lifton, Tom Maniatis, Trine H. Mogensen, Horst von Bernuth, Alban Lermine, Michel Vidaud, Anne Boland, Jean‐François Deleuze, Robert Nussbaum, Amanda Kahn-Kirby, France Mentré, Sarah Tubiana, Guy Gorochov, Florence Tubach, Pierre Hausfater, Laurent Abel, Saleh Al‐Muhsen, Fahd Al‐Mulla, Mark Anderson, Evangelos Andreakos, Andrés A. Arias, Hagit Baris Feldman, Alexandre Bélot, Catherine M. Biggs, Dusan Bogunovic, Анастасія Бондаренко, Ahmed Aziz Bousfiha, Petter Brodin, Yenan T. Bryceson, Carlos D. Bustamante, Samya Chakravorty, John Christodoulou, Murkesh Desai, Beth A. Drolet, Jamila El Baghdadi, Sara Elva Espinosa‐Padilla, José Luis Franco, Antoine Froidure, David Hagin, Sarah E. Henrickson, Elena W.Y. Hsieh, Eystein S. Husebye, Kohsuke Imai, Yuval Itan, Erich D. Jarvis, Timokratis Karamitros, Kai Kisand, Cheng‐Lung Ku, Yun Ling, C. Lucas, László Maródi, Isabelle Meyts, Joshua D. Milner, Kristina Mironska, Tomohiro Morio, Lisa F. P. Ng, Luigi D. Notarangelo, Cliona OʼFarrelly, Satoshi Okada, Anna M. Planas, Lluís Quintana‐Murci, Laurent Rénia, Igor Resnick, Carlos Rodríguez‐Gallego, Vanessa Sancho‐Shimizu, Anna Šedivá, Mikko Seppänen, Anna Shcherbina, Ondřej Slabý, Andrew L. Snow, Pere Soler‐Palacín, András N. Spaan, Ivan Tancevski, Stuart G. Tangye, Sathishkumar Ramaswamy, Stuart E. Turvey, K. M. Furkan Uddin, Mohammed Uddin, Diederik van de Beek, Donald C. Vinh, Mayana Zatz, Helen C. Su, Jean‐Laurent Casanova, Serge Bureau, Yannick Vacher, Anne Gysembergh-Houal, Lauren Demerville, Abla Chachoua, Sébastien Abad, Radhiya Abassi, Abdelrafie Abdellaoui, Abdelkrim Abdelmalek, Hendy Abdoul, Hélène Abergel, Fariza Abeud, Sophie Abgrall, Noémie Abisror, Marylise Adechian, Nordine Aderdour, Hakeem Farid Admane, Frédéric Adnet, Sara Afritt, Hélène Agostini, Claire Aguilar, Sophie Agut, Tommaso Francesco Aiello, Marc Ait Kaci, Hafid Aït-Oufella, Gokula Ajeenthiravasan, Virginie Alauzy, Fanny Alby‐Laurent, Lucie Allard, Marie‐Alexandra Alyanakian, Blanca Amador Borrero, Sabrina Amam, Lucile Amrouche, M. Andronikof, Dany Anglicheau, Nadia Anguel, Djillali Annane, Mohammed Aounzou, C. Aparicio, Gladys Aratus, Jean‐Benoît Arlet, Jérémy Arzoine, E. Aslangul, Mona Assefi, Adeline Aubry, Laetitia Audiffred, Étienne Audureau, Christelle Nathalie Auger, Jean-Charles Aurégan, Celine Awotar, Sonia Ayllon Milla, Delphine Azan, Laurene Azemar, Billal Azzouguen, Marwa Bachir Elrufaai, Aïda Badsi, Prissile Bakouboula, Coline Balcerowiak, Fanta Balde, Elodie Baldivia, Eliane-Flore Bangamingo, Amandine Baptiste, Fanny Baran‐Marszak, Caroline Barau, Nathalie Barget, Flore Baronnet, Romain Barthélémy, Jean-Luc Baudel, Camille Baudry, Élodie Baudry, Laurent Beaugerie, Adel Belamri, Nicolas Belaube, Rhida Belilita, Pierre Bellassen, Rawan Belmokhtar, Isabel Beltrán, Ruben Benaïnous, Mourad Benallaoua, Robert Benamouzig, Amélie Benbara, Jaouad Benhida, Anis Benkhelouf, Jihene Benlagha, Chahinez Benmostafa, Skander Benothmane, Miassa Bentifraouine, Laurence Bérard, Quentin Bernier, Emilio Berti, Astrid Bertier, Laure Berton, Simon Bessis, Alexandra Beurton, Céline Bianco, Clara Bianquis, Frank Bidar, P. Blanche, Clarisse Blayau, Alexandre Bleibtreu, Emmanuelle Blin, Coralie Bloch‐Queyrat, Marie‐Christophe Boissier, Diane Bollens, Marion Bolzoni, Rudy pierre Bompard, Nicolas Bonnet, Justine Bonnouvrier, Shirmonecrystal Botha, Wissam Boucenna, Fatiha Bouchama, Olivier Bouchaud, Hanane Bouchghoul, Taoueslylia Boudjebla, Noel Boudjema, Catherine Bouffard, Adrien Bouglé, Meriem Bouguerra, Leila Bouras,
Abstract Background We previously reported that impaired type I IFN activity, due to inborn errors of TLR3- and TLR7-dependent type I interferon (IFN) immunity or to autoantibodies against type I IFN, account for 15–20% of cases of life-threatening COVID-19 in unvaccinated patients. Therefore, the determinants of life-threatening COVID-19 remain to be identified in ~ 80% of cases. Methods We report here a genome-wide rare variant burden association analysis in 3269 unvaccinated patients with life-threatening ...
BioMed Central
Qian Zhang, Paul Bastard, Zhiyong Liu, Jérémie Le Pen, Marcela Moncada‐Vélez, Jie Chen, Masato Ogishi, Ira K. D. Sabli, Stephanie Hodeib, Cecilia B. Korol, Jérémie Rosain, Kaya Bilgüvar, Junqiang Ye, Alexandre Bolze, Benedetta Bigio, Rui Yang, Andrés A. Arias, Qinhua Zhou, Yu Zhang, Fanny Onodi, Sarantis Korniotis, Léa Karpf, Quentin Philippot, Marwa Chbihi, Lucie Bonnet‐Madin, Karim Dorgham, Nikaïa Smith, William M. Schneider, Brandon S. Razooky, Hans-Heinrich Hoffmann, Eleftherios Michailidis, Leen Moens, Ji Eun Han, Lazaro Lorenzo, Lucy Bizien, Philip Meade, Anna‐Lena Neehus, Aileen Camille Ugurbil, Aurélien Corneau, Gaspard Kerner, Peng Zhang, Franck Rapaport, Yoann Seeleuthner, Jérémy Manry, Cécile Masson, Yohann Schmitt, Agatha Schlüter, Tom Le Voyer, Taushif Khan, Juan Li, Jacques Fellay, Lucie Roussel, Mohammad Shahrooei, Mohammed F. Alosaimi, Davood Mansouri, Haya Al‐Saud, Fahd Al‐Mulla, Feras Almourfi, Saleh Zaid Al-Muhsen, Fahad Alsohime, Saeed Al Turki, Rana Hasanato, Diederik van de Beek, Andrea Biondi, Laura Rachele Bettini, Mariella D’Angiò, Paolo Bonfanti, Luisa Imberti, Alessandra Sottini, Simone Paghera, Eugenia Quirós-Roldán, Camillo Rossi, Andrew J. Oler, Miranda F. Tompkins, Camille Alba, Isabelle Vandernoot, Jean‐Christophe Goffard, Guillaume Smits, Isabelle Migeotte, Filomeen Haerynck, Pere Soler‐Palacín, Andrea Martín-Nalda, Roger Colobrán, Pierre‐Emmanuel Morange, Sevgi Keleş, Fatma Çölkesen, Tayfun Özçelık, Kadriye Kart Yaşar, Sevtap Şenoğlu, Şemsi̇ Nur Karabela, Carlos Rodríguez‐Gallego, Giuseppe Novelli, Sami Hraiech, Yacine Tandjaoui-Lambiotte, Xavier Duval, Cédric Laouénan, Andrew L. Snow, Clifton L. Dalgard, Joshua D. Milner, Donald C. Vinh, Trine H. Mogensen, Nico Marr, András N. Spaan, Bertrand Boisson, Stéphanie Boisson‐Dupuis, Jacinta Bustamante, Anne Puel, Michael J. Ciancanelli, Isabelle Meyts, Tom Maniatis, Vassili Soumelis, Ali Amara, Michel C. Nussenzweig, Adolfo Garcı́a-Sastre, Florian Krammer, Aurora Pujol, Darragh Duffy, Richard P. Lifton, Shen‐Ying Zhang, Guy Gorochov, Vivien Béziat, Emmanuelle Jouanguy, Vanessa Sancho‐Shimizu, Charles M. Rice, Laurent Abel, Luigi D. Notarangelo, Aurélie Cobat, Helen C. Su, Jean‐Laurent Casanova, Giuseppe Foti, Giacomo Bellani, Giuseppe Citerio, Ernesto Contro, Alberto Pesci, Maria Grazia Valsecchi, Marina Elena Cazzaniga, Jorge Abad, Sergio Aguilera, Özge Metin Akcan, Ilad Alavi Darazam, Juan C. Aldave, Miquel Alfonso Ramos, Seyed Alireza Nadji, Gülsüm Alkan, Jérôme Allardet-Servent, Luís M. Allende, Laia Alsina, Marie‐Alexandra Alyanakian, Blanca Amador-Borrero, Zahir Amoura, Arnau Antolí, Şevket Arslan, Sophie Trouillet‐Assant, Teresa Auguet, Axelle Azot, Fanny Bajolle, Aurélie Baldolli, Mayte Ballester, Hagit Baris Feldman, Benoı̂t Barrou, Alexandra Beurton, Agurtzane Bilbao, Géraldine Blanchard-Rohner, Ignacio Blanco, Adeline Blandinières, Daniel Blázquez‐Gamero, Markéta Bloomfield, Mireia Bolívar-Prados, Raphaël Borie, Cédric Bosteels, Ahmed Aziz Bousfiha, Claire Bouvattier, Oksana Boyarchuk, Maria Rita Passos‐Bueno, Jacinta Bustamante, Juan José Cáceres Agra, Semra Calimli, Ruggero Capra, Maria Carrabba, Carlos Casasnovas, Marion Caséris, Martin Castelle, Francesco Castelli, Martín Castillo de Vera, Mateus Vidigal de Castro, Émilie Catherinot, Martin Chalumeau, Bruno Charbit, Matthew P. Cheng, Père Clavé, Bonaventura Clotet, Anna Codina, Fatih Çölkesen, Fatma Çölkesen, Roger Colobrán, Cloé Comarmond, David Dalmau, D.R. Darley, Nicolás Dauby, Stéphane Dauger, Loïc de Pontual, Amin Dehban, Geoffroy Delplancq, Alexandre Demoule, Jean‐Luc Diehl, Stephanie Dobbelaere, Sophie Durand, Waleed Eldars, Mohamed Elgamal, Marwa H. Elnagdy, Melike Emiroğlu, Emine Hafize Erdeniz, Selma Erol Aytekin, Romain Euvrard, Recep Evcen, Fabio Gavarini, Laurence Faivre, Antonin Falck, Muriel Fartoukh, Morgane Faure, Miguel Fernández‐Arquero, Carlos Flores, Bruno François, Victòria Fumadó, Francesca Fusco, Blanca García‐Solis, Pascale Gaussem, Juana Gil-Herrera, Laurent Gilardin, Monica Girona Alarcon, Mònica Girona‐Alarcón, Jean‐Christophe Goffard, Funda Gök, Rafaela González‐Montelongo, Antoine Guerder, Yahya Gül, Şükrü Nail Güner, Marta Gut, Jérôme Hadjadj, Filomeen Haerynck, Rabih Halwani, Lennart Hammarström, Nevin Hatipoğlu, Elisa Hernández-Brito, Cathérine Heijmans, M.S. Holanda Peña, Juan Pablo Horcajada, Levi Hoste, Eric A. J. Hoste, Sami Hraiech, L. Humbert, Alejandro Iglesias, Antonio Íñigo-Campos, Matthieu Jamme, María J. Arranz, Iolanda Jordán, Philippe G. Jorens, Fikret Kanat, Hasan Kapaklı, Iskender Kara, Adem Karbuz, Kadriye Kart Yaşar, Sevgi Keleş, Yasemin Kendir Demirkol, Adam Klocperk, Zbigniew Król, Paul Kuentz, Mike Yat Wah Kwan, Jean‐Christophe Lagier, Bart N. Lambrecht, YL Lau, Fleur Le Bourgeois, Yee‐Sin Leo, Rafael León‐López, Daniel Leung, Michael Levin, Michaël Levy, Romain Lévy, Zhi Li, Agnès Linglart, Bart Loeys, José M. Lorenzo-Salazar, Céline Louapre, Catherine Lubetzki, Charles‐Édouard Luyt, David Chien Lye, Davood Mansouri, Majid Marjani, Jesus Marquez Pereira, Andrea Martín‐Nalda, David Martínez Pueyo, Javier Martínez‐Picado, Iciar Marzana, Alexis Mathian, Larissa R. B. Matos, Gail Matthews,
The genetics underlying severe COVID-19 The immune system is complex and involves many genes, including those that encode cytokines known as interferons (IFNs). Individuals that lack specific IFNs can be more susceptible to infectious diseases. Furthermore, the autoantibody system dampens IFN response to prevent damage from pathogen-induced inflammation. Two studies now examine the likelihood that genetics affects the risk of severe coronavirus disease 2019 (COVID-19) through components of this system ( ...
American Association for the Advancement of Science
Paul Bastard, Lindsey B. Rosen, Qian Zhang, Eleftherios Michailidis, Hans-Heinrich Hoffmann, Yu Zhang, Karim Dorgham, Quentin Philippot, Jérémie Rosain, Vivien Béziat, Jérémy Manry, Elana Shaw, Liis Haljasmägi, Pärt Peterson, Lazaro Lorenzo, Lucy Bizien, Sophie Trouillet‐Assant, Kerry Dobbs, Adriana A. de Jesus, Alexandre Bélot, Anne Kallaste, Émilie Catherinot, Yacine Tandjaoui-Lambiotte, Jérémie Le Pen, Gaspard Kerner, Benedetta Bigio, Yoann Seeleuthner, Rui Yang, Alexandre Bolze, András N. Spaan, Ottavia M. Delmonte, Michael S. Abers, Alessandro Aiuti, Giorgio Casari, Vito Lampasona, Lorenzo Piemonti, Fabio Ciceri, Kaya Bilgüvar, Richard P. Lifton, Marc Vasse, David M. Smadja, Mélanie Migaud, Jérôme Hadjadj, Benjamin Terrier, Darragh Duffy, Lluís Quintana‐Murci, Diederik van de Beek, Lucie Roussel, Donald C. Vinh, Stuart G. Tangye, Filomeen Haerynck, David Dalmau, Javier Martínez‐Picado, Petter Brodin, Michel C. Nussenzweig, Stéphanie Boisson‐Dupuis, Carlos Rodríguez‐Gallego, Guillaume Vogt, Trine H. Mogensen, Andrew J. Oler, Jingwen Gu, Peter D. Burbelo, Jeffrey I. Cohen, Andrea Biondi, Laura Rachele Bettini, Mariella D’Angiò, Paolo Bonfanti, Patrick Rossignol, Julien Mayaux, Frédéric Rieux‐Laucat, Eystein S. Husebye, Francesca Fusco, Matilde Valeria Ursini, Luisa Imberti, Alessandra Sottini, Simone Paghera, Eugenia Quirós-Roldán, Camillo Rossi, Riccardo Castagnoli, Daniela Montagna, Amelia Licari, Gian Luigi Marseglia, Xavier Duval, Jade Ghosn, John S. Tsang, Raphaela Goldbach‐Mansky, Kai Kisand, Michail S. Lionakis, Anne Puel, Shen‐Ying Zhang, Steven M. Holland, Guy Gorochov, Emmanuelle Jouanguy, Charles M. Rice, Aurélie Cobat, Luigi D. Notarangelo, Laurent Abel, Helen C. Su, Jean‐Laurent Casanova, Andrés A. Arias, Bertrand Boisson, Soraya Boucherit, Jacinta Bustamante, Marwa Chbihi, Jie Chen, Maya Chrabieh, Tatiana Kochetkov, Tom Le Voyer, Dana Liu, Yelena Nemirovskaya, Masato Ogishi, Dominick Papandrea, Cécile Patissier, Franck Rapaport, Manon Roynard, Natasha Vladikine, Mark Woollett, Peng Zhang, Anuj Kashyap, Li Ding, Marita Bosticardo, Qinlu Wang, Sebastian Ochoa, Hui Liu, Samuel D. Chauvin, Michael Stack, Galina Koroleva, Neha Bansal, Clifton L. Dalgard, Andrew L. Snow, Jorge Abad, Sergio Aguilera, Özge Metin Akcan, Ilad Alavi Darazam, Juan C. Aldave, Miquel Alfonso Ramos, Seyed Alireza Nadji, Gülsüm Alkan, Jérôme Allardet-Servent, Luís M. Allende, Laia Alsina, Marie‐Alexandra Alyanakian, Blanca Amador-Borrero, Zahir Amoura, Arnau Antolí, Şevket Arslan, Sophie Assant, Teresa Auguet, Axelle Azot, Fanny Bajolle, Aurélie Baldolli, Mayte Ballester, Hagit Baris Feldman, Benoı̂t Barrou, Alexandra Beurton, Agurtzane Bilbao, Géraldine Blanchard-Rohner, Ignacio Blanco, Adeline Blandinières, Daniel Blázquez‐Gamero, Markéta Bloomfield, Mireia Bolívar-Prados, Raphaël Borie, Ahmed Aziz Bousfiha, Claire Bouvattier, Oksana Boyarchuk, Maria Rita Passos‐Bueno, Jacinta Bustamante, Juan José Cáceres Agra, Semra Calimli, Ruggero Capra, Maria Carrabba, Carlos Casasnovas, Marion Caséris, Martin Castelle, Francesco Castelli, Martín Castillo de Vera, Mateus Vidigal de Castro, Émilie Catherinot, Martin Chalumeau, Bruno Charbit, Matthew Pellan Cheng, Père Clavé, Bonaventura Clotet, Anna Codina, Fatih Çölkesen, Fatma Çölkesen, Roger Colobrán, Cloé Comarmond, Angelo Guido Corsico, David Dalmau, D.R. Darley, Nicolás Dauby, Stéphane Dauger, Loïc de Pontual, Amin Dehban, Geoffroy Delplancq, Alexandre Demoule, Antonio Di Sabatino, Jean‐Luc Diehl, Stephanie Dobbelaere, Sophie Durand, Waleed Eldars, Mohamed Elgamal, Marwa H. Elnagdy, Melike Emiroğlu, Emine Hafize Erdeniz, Selma Erol Aytekin, Romain Euvrard, Recep Evcen, Fabio Gavarini, Laurence Faivre, Antonin Falck, Muriel Fartoukh, Morgane Faure, Miguel Fernández‐Arquero, Carlos Flores, Bruno François, Victòria Fumadó, Francesca Fusco, Blanca García‐Solis, Pascale Gaussem, Juana Gil-Herrera, Laurent Gilardin, Monica Girona Alarcon, Mònica Girona‐Alarcón, Jean‐Christophe Goffard, Funda Gök, Rafaela González‐Montelongo, Antoine Guerder, Yahya Gül, Şükrü Nail Güner, Marta Gut, Jérôme Hadjadj, Filomeen Haerynck, Rabih Halwani, Lennart Hammarström, Nevin Hatipoğlu, Elisa Hernández-Brito, M.S. Holanda Peña, Juan Pablo Horcajada, Sami Hraiech, L. Humbert, Alejandro Iglesias, Antonio Íñigo-Campos, Matthieu Jamme, María J. Arranz, Iolanda Jordán, Fikret Kanat, Hasan Kapaklı, Iskender Kara, Adem Karbuz, Kadriye Kart Yaşar, Sevgi Keleş, Yasemin Kendir Demirkol, Adam Klocperk, Zbigniew Król, Paul Kuentz, Mike Yat Wah Kwan, Jean‐Christophe Lagier, YL Lau, Fleur Le Bourgeois, Yee‐Sin Leo, Rafael León‐López, Daniel Leung, Michael Levin, Michaël Levy, Romain Lévy, Zhi Li, Agnès Linglart, José M. Lorenzo-Salazar, Céline Louapre, Catherine Lubetzki, Charles‐Édouard Luyt, David Chien Lye, Davood Mansouri, Majid Marjani, Jesus Marquez Pereira, Andrea Martín‐Nalda, David Martínez Pueyo, Javier Martínez‐Picado, Iciar Marzana, Alexis Mathian, Larissa R. B. Matos, Gail Matthews, Julien Mayaux, Jean‐Louis Mège, Isabelle Melki, Jean–François Méritet, Özge Metin Akcan, Isabelle Meyts, Mehdi Mezidi, Isabelle Migeotte, Maude Millereux, Tristan Mirault, Clotilde Mircher,
Interindividual clinical variability in the course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is vast. We report that at least 101 of 987 patients with life-threatening coronavirus disease 2019 (COVID-19) pneumonia had neutralizing immunoglobulin G (IgG) autoantibodies (auto-Abs) against interferon-ω (IFN-ω) (13 patients), against the 13 types of IFN-α (36), or against both (52) at the onset of critical disease; a few also had auto-Abs against the other three type I IFNs. ...
American Association for the Advancement of Science
Gemma Bullich, Leslie Matalonga, Montserrat Pujadas, Anastasios Papakonstantinou, Davide Piscia, Raúl Tonda, Rafael Artuch, P. Gallano, Glòria Garrabou, Juan R. González, Daniel Grinberg, Míriam Guitart, Steven Laurie, Conxi Lázaro, Cristina Luengo, Ramón Martí, Montserrat Milà, David Ovelleiro, Genı́s Parra, Aurora Pujol, Eduardo F. Tizzano, Alfons Macaya, Francesc Palau, Antònia Ribes, Luis A. Pérez‐Jurado, Sergi Beltrán, Agatha Schlüter, Agustí Rodríguez‐Palmero, Alejandro Cáceres, A. Nascimento, Àngels García‐Cazorla, Anna M. Cueto‐González, Anna Marcé‐Grau, A. Lô, Antonio Federico Martínez‐Monseny, Aurora Sánchez, Belén de la Fuente García, Belén Pérez‐Dueñas, Bernat Gel, Berta Fusté, Carles Hernández-Ferrer, Carlos Casasnovas, C. Ortez, César Arjona, Cristina Hernando‐Davalillo, Daniel Natera‐de Benito, Daniel Picó Amador, David Gómez‐Andrés, Dèlia Yubero, Dolors Pelegrí-Sisó, Edgard Verdura, Elena García‐Arumí, Elisabeth Castellanos, Elisabeth Gabau, Ester Tobías, Fermina López‐Grondona, Francesc Cardellach, Francesc Josep García‐García, Francina Munell, Frederic Tort, Gemma Aznar, Gemma Olivé-Cirera, Gemma Tell‐Martí, Gerard Muñoz-Pujol, Ida Paramonov, Ignacio Blanco, Irene Madrigal, Irene Valenzuela, Marta Gut, Ivon Cuscó, Jean-Rémi Trotta, Jordi Cruz, Jordi Díaz‐Manera, José C. Milisenda, Josep Ma Grau, Judit García‐Villoria, Judith Armstrong, Judith Cantó, Júlia Sala‐Coromina, Laia Rodríguez‐Revenga, Laura Alías, Laura Gort, Lidia González‐Quereda, Mar Costa, Marcos Fernández-Callejo, Marcos López‐Sánchez, María Isabel Álvarez‐Mora, Marta Gut, Mercedes Serrano, Miquel Raspall‐Chaure, Mireia del Toro, Mónica Bayés, Neus Baena Díez, Nino Spataro, Núria Capdevila, Olatz Ugarteburu, Patricia Muñoz‐Cabello, P. Romero Duque, Raquel Rabionet, Ricard Rojas‐García, Rosa Calvo, Roser Urreizti, Sara Bernal, Susana Boronat, Susana Balcells, Teresa Vendrell,
Many patients experiencing a rare disease remain undiagnosed even after genomic testing. Reanalysis of existing genomic data has shown to increase diagnostic yield, although there are few systematic and comprehensive reanalysis efforts that enable collaborative interpretation and future reinterpretation. The Undiagnosed Rare Disease Program of Catalonia project collated previously inconclusive good quality genomic data (panels, exomes, and genomes) and standardized phenotypic profiles from 323 families ( ...
Tópico(s): Genetic Syndromes and Imprinting
2022 - Elsevier BV | Journal of Molecular Diagnostics
Jérémy Manry, Paul Bastard, Adrian Gervais, Tom Le Voyer, Jérémie Rosain, Quentin Philippot, Eleftherios Michailidis, Hans-Heinrich Hoffmann, Shohei Eto, Marina García-Prat, Lucy Bizien, Alba Parra-Martínez, Rui Yang, Liis Haljasmägi, Mélanie Migaud, Karita Särekannu, Julia Maslovskaja, Nicolas de Prost, Yacine Tandjaoui-Lambiotte, Charles‐Édouard Luyt, Blanca Amador-Borrero, Alexandre Gaudet, Julien Poissy, Pascal Morel, Pascale Richard, Fabrice Cognasse, Jesús Troya, Sophie Trouillet‐Assant, Alexandre Bélot, Kahina Saker, Pierre Garçon, Jacques G. Rivière, Jean‐Christophe Lagier, Stéphanie Gentile, Lindsey B. Rosen, Elana Shaw, Tomohiro Morio, Junko Tanaka, David Dalmau, Pierre‐Louis Tharaux, D. Sène, Alain Stépanian, Bruno Mégarbane, Vasiliki Triantafyllia, Arnaud Fekkar, James R. Heath, José Luis Franco, Juan‐Manuel Anaya, Jordi Solé‐Violán, Luisa Imberti, Andrea Biondi, Paolo Bonfanti, Riccardo Castagnoli, Ottavia M. Delmonte, Yu Zhang, Andrew L. Snow, Steven M. Holland, Catherine M. Biggs, Marcela Moncada‐Vélez, Andrés A. Arias, Lazaro Lorenzo, Soraya Boucherit, Dany Anglicheau, Anna M. Planas, Filomeen Haerynck, Sotiriјa Duvlis, Tayfun Özçelık, Sevgi Keleş, Ahmed Aziz Bousfiha, Jalila El Bakkouri, Carolina Ramírez‐Santana, Stéphane Paul, Qiang Pan‐Hammarström, Lennart Hammarström, Annabelle Dupont, Alina Kurolap, Christine N. Metz, Alessandro Aiuti, Giorgio Casari, Vito Lampasona, Fabio Ciceri, Lucila Akune Barreiros, Elena Domínguez‐Garrido, Mateus Vidigal, Mayana Zatz, Diederik van de Beek, Sabina Sahanic, Ivan Tancevski, Yuriy Stepanovskyy, Oksana Boyarchuk, Yoko Nukui, Miyuki Tsumura, Loreto Vidaur, Stuart G. Tangye, Sonia Burrel, Darragh Duffy, Lluís Quintana‐Murci, Adam Klocperk, Nelli Y. Kann, Anna Shcherbina, YL Lau, Daniel Leung, Matthieu Coulongeat, Julien Marlet, Rutger Koning, Luis Felipe Reyes, Angélique Chauvineau‐Grenier, Fabienne Venet, Guillaume Monneret, Michel C. Nussenzweig, Romain Arrestier, Idris Boudhabhay, Hagit Baris Feldman, David Hagin, Joost Wauters, Isabelle Meyts, Adam H. Dyer, Seán Kennelly, Nollaig M. Bourke, Rabih Halwani, Fatemeh Saheb Sharif‐Askari, Karim Dorgham, Jérôme Sallette, Souad Mehlal Sedkaoui, Suzan A. AlKhater, Raúl Rigo‐Bonnin, Francisco Morandeira, Lucie Roussel, Donald C. Vinh, Christian Erikstrup, Antônio Condino‐Neto, Carolina Prando, Анастасія Бондаренко, András N. Spaan, Laurent Gilardin, Jacques Fellay, Stanislas Lyonnet, Kaya Bilgüvar, Richard P. Lifton, Shrikant Mane, Mark S. Anderson, Bertrand Boisson, Vivien Béziat, Shen‐Ying Zhang, Evangelos Andreakos, Olivier Hermine, Aurora Pujol, Pärt Peterson, Trine H. Mogensen, Lee Rowen, James Mond, Stéphanie Debette, Xavier de Lamballerie, Charles Burdet, Lila Bouadma, Marie Zins, Pere Soler‐Palacín, Roger Colobrán, Guy Gorochov, Xavier Solanich, Sophie Susen, Javier Martínez‐Picado, Didier Raoult, Marc Vasse, Peter K. Gregersen, Lorenzo Piemonti, Carlos Rodríguez‐Gallego, Luigi D. Notarangelo, Helen C. Su, Kai Kisand, Satoshi Okada, Anne Puel, Emmanuelle Jouanguy, Charles M. Rice, Pierre Tiberghien, Qian Zhang, Jean‐Laurent Casanova, Laurent Abel, Aurélie Cobat, Peng Zhang, Yoann Seeleuthner, Estelle Talouarn, Astrid Marchal, Daniela Matuozzo, Aliénor de la Chapelle, Jie Chen, Maya Chrabieh, Dana Liu, Yelena Nemirowskaya, Inés Marín Cruz, Marie Materna, Sophie Pelet, C Thibault, Xiaogang Li, Jorge Abad, Giulia Accordino, Cristian Achille, Sergio Aguilera, Aina Aguiló‐Cucurull, Alessandro Aiuti, Esra Akyüz Özkan, Ilad Alavi Darazam, Jonathan Antonio Roblero Albisures, Juan C. Aldave, Miquel Alfonso Ramos, Sajid Ali, Anna Aliberti, Seyed Alireza Nadji, Gülsüm Alkan, Suzan A. AlKhater, Jérôme Allardet-Servent, Luís M. Allende, Rebeca Alonso‐Arias, Mohammed Alshahrani, Laia Alsina, Marie‐Alexandra Alyanakian, Blanca Amador Borrero, Zahir Amoura, Arnau Antolí, Romain Arrestier, Mélodie Aubart, Teresa Auguet, Iryna Avramenko, Gökhan Aytekіn, Axelle Azot, Seiamak Bahram, Fanny Bajolle, Fausto Baldanti, Aurélie Baldolli, Mayte Ballester, Hagit Baris Feldman, Benoı̂t Barrou, Federica Barzaghi, Sabrina Basso, Gülsüm İclal Bayhan, Alexandre Bélot, Liliana Bezrodnik, Agurtzane Bilbao, Géraldine Blanchard-Rohner, Ignacio Blanco, Adeline Blandinières, Daniel Blázquez‐Gamero, Alexandre Bleibtreu, Markéta Bloomfield, Mireia Bolívar-Prados, Анастасія Бондаренко, A. Borghesi, Raphaël Borie, Elisabeth Botdhlo-Nevers, Ahmed Aziz Bousfiha, Aurore Bousquet, David Boutolleau, Claire Bouvattier, Oksana Boyarchuk, Juliette Bravais, M. Luisa Briones, Marie-Eve Brunner, Raffaele Bruno, Maria Rita Passos‐Bueno, Huda Bukhari, Jacinta Bustamante, Juan José Cáceres Agra, Ruggero Capra, Raphaël Carapito, Maria Carrabba, Giorgio Casari, Carlos Casasnovas, Marion Caséris, Irene Cassaniti, Martin Castelle, Francesco Castelli, Martín Castillo de Vera, Mateus Vidigal de Castro, Émilie Catherinot, Jale Bengi Çelik, Alessandro Ceschi, Martin Chalumeau, Bruno Charbit, Matthew Pellan Cheng, Père Clavé, Bonaventura Clotet, Anna Codina, Yves Cohen, Roger Colobrán, Cloé Comarmond, Alain Combes, Patrizia Comoli, Angelo Guido Corsico, Taner Çoşkuner, Aleksandar Cvetkovski, Cyril Cyrus, David Dalmau, François Danion, D.R. Darley, Vincent Das, Nicolás Dauby,
Significance There is growing evidence that preexisting autoantibodies neutralizing type I interferons (IFNs) are strong determinants of life-threatening COVID-19 pneumonia. It is important to estimate their quantitative impact on COVID-19 mortality upon SARS-CoV-2 infection, by age and sex, as both the prevalence of these autoantibodies and the risk of COVID-19 death increase with age and are higher in men. Using an unvaccinated sample of 1,261 deceased patients and 34,159 individuals from the general ...
National Academy of Sciences
Renato Mantegazza, Gil I. Wolfe, Srikanth Muppidi, Heinz Wiendl, Kenji P. Fujita, Fanny O’Brien, Heather Booth, James F. Howard, Claudio Mazia, Miguel Wilken, Fábio Barroso, Juliet Saba, Marcelo Rugiero, Mariela Bettini, Marcelo Chaves, Gonzalo Vidal, Alejandra Dalila Garcia, Jan De Bleecker, Guy Van den Abeele, Kathy de Koning, Katrien De Mey, Rudy Mercelis, Délphine Mahieu, Linda Wagemaekers, Philip Van Damme, Annelies Depreitere, Caroline Schotte, Charlotte Smetcoren, Olivier Stevens, Sien Van Daele, Nicolas Vandenbussche, Annelies Vanhee, Sarah Verjans, Jan Vynckier, Ann D’Hont, Petra Tilkin, Alzira Alves de Siqueira Carvalho, Igor Dias Brockhausen, David Feder, Daniel Ambrosio, Gabor Lovasamela César, Ana Paula Souto Melo, Renata Martins Ribeiro, Rosana Rocha, Bruno Bezerra Rosa, Thabata Veiga, Luiz Augusto da Silva, Murilo Santos Engel, Jordana Gonçalves Geraldo, Maria da Penha Ananias Morita, Érica Coelho, Gabriel Pina Paiva, M Tovar Pozo, Natalia Prando, Debora Dada Martineli Torres, Cristiani Fernanda Butinhao, Gustavo Duran, Tomás Augusto Suriane Fialho, Tamires Cristina Gomes da Silva, Luiz Otavio Maia Gonçalves, Lucas Eduardo Pazetto, Luciana Renata Cubas Volpe, Luciana Souza Duca, Maurício AndréGheller Friedrich, Alexandre Guerreiro, Alexandre Guerreiro, Henrique Mohr, Maurer Pereira Martins, Daiane da Cruz Pacheco, Luciana Ferreira, Ana Paula Macagnan, Graziela Hünning Pinto, Aline de Cassia Santos, Acary Souza Bullé Oliveira, Ana Carolina Amaral de Andrade, Marcelo Annes, Liene Duarte Silva, Valéria Cavalcante Lino, Wladimir Bocca Vieira de Rezende Pinto, Natália Assis, Fernanda Carrara, Carolina Miranda, Iandra Souza, Ana Patrícia Fernandes, Zaeem A. Siddiqi, Cecile Phan, Jeffrey Narayan, Derrick Blackmore, Ashley Mallon, Rikki Roderus, Elizabeth Watt, Stanislav Voháňka, Josef Bednařík, Magda Chmelikova, Marek Čierny, Stanislava Toncrova, Jana Junkerová, Barbora Kurková, Katarína Reguliová, Olga Zapletalová, Jiří Piťha, Iveta Nováková, Michaela Týblová, Ivana Jurajdova, Marcela Wolfova, Henning Andersen, Thomas Harbo, Lotte Vinge, Susanne Krogh, Anita Mogensen, John Vissing, Joan Højgaard, Nanna Witting, Anne Mette Ostergaard Autzen, Jane Pedersen, Juha-Pekka Erälinna, Mikko Laaksonen, Olli Oksaranta, Tuula Harrison, Jaana Eriksson, Csilla Rózsa, Melinda Horvath, Gábor Lovas, Judit Matolcsi, Gedeonne Jakab, G Szabó, Gedeonne Jakab, Brigitta Szabadosne, László Vécsei, Lívia Dézsi, Edina Varga, Monika Konyane, Giovanni Antonini, Antonella Di Pasquale, Matteo Garibaldi, Stefania Morino, Fernanda Troili, Laura Fionda, Antonella Di Pasquale, Amelia Evoli, Paolo Emilio Alboini, Valentina Damato, Raffaele Iorio, Maurizio Inghilleri, Laura Fionda, Vittorio Frasca, Elena Giacomelli, Maria Cristina Gori, Diego Lopergolo, Emanuela Onesti, Vittorio Frasca, Maria Gabriele, Francesco Saccà, Alessandro Filla, Teresa Costabile, Enrico Marano, Angiola Maria Fasanaro, Angela Marsili, Giorgia Puorro, Carlo Antozzi, Silvia Bonanno, Giorgia Camera, Alberta Locatelli, Lorenzo Maggi, Maria Barbara Pasanisi, Angela Campanella, Akiyuki Uzawa, Tetsuya Kanai, Naoki Kawaguchi, Masahiro Mori, Yoko Kaneko, Akiko Kanzaki, Eri Kobayashi, Hiroyuki Murai, Katsuhisa Masaki, Dai Matsuse, Takuya Matsushita, Taira Uehara, Misa Shimpo, Maki Jingu, Keiko Kikutake, Yumiko Nakamura, Yoshiko Sano, Kimiaki Utsugisawa, Yuriko Nagane, Ikuko Kamegamori, Tomoko Tsuda, Yuko Fujii, Kazumi Futono, Yukiko Ozawa, Aya Mizugami, Yuka Saito, Makoto Samukawa, Hidekazu Suzuki, Miyuki Morikawa, Sachiko Kamakura, Eriko Miyawaki, Meinoshin Okumura, Soichiro Funaka, Tomohiro Kawamura, Masayuki Nakamori, Masanori Takahashi, Namie Taichi, Tomoya Hasuike, Eriko Higuchi, Hisako Kobayashi, Kaori Osakada, Hirokazu Shiraishi, Teiichiro Miyazaki, Masakatsu Motomura, Akihiro Mukaino, Shunsuke Yoshimura, Shizuka Asada, Seiko Yoshida, Shoko Amamoto, Tomomi Kobashikawa, Megumi Koga, Maeda Yasuko, Kazumi Takada, Mihoko Takada, Masako Tsurumaru, Yumi Yamashita, Yasushi Suzuki, Tetsuya Akiyama, Koichi Narikawa, Ohito Tano, Kenichi Tsukita, Rikako Kurihara, Fumie Meguro, Yusuke Fukuda, Miwako Sato, Tomihiro Imai, Emiko Tsuda, Shun Shimohama, Takashi Hayashi, Shin Hisahara, Tomihiro Imai, Jun Kawamata, Takashi Murahara, Masaki Saitoh, Shun Shimohama, Shu-Ichiro Suzuki, Daisuke Yamamoto, Yoko Ishiyama, Naoko Ishiyama, Mayuko Noshiro, Rumi Takeyama, Kaori Uwasa, Ikuko Yasuda, Anneke J. van der Kooi, Marianne de Visser, Tamar Gibson, Byung‐Jo Kim, Chang Nyoung Lee, Yong Seo Koo, Hung Youl Seok, Hoo Nam Kang, HyeJin Ra, Byoung Joon Kim, Eun Bin Cho, Misong Choi, HyeLim Lee, Ju‐Hong Min, Jinmyoung Seok, Ji‐Eun Lee, Da Yoon Koh, JuYoung Kwon, SangAe Park, Eun Haw Choi, Yoon‐Ho Hong, Sohyun Ahn, Dae Lim Koo, Jae‐Sung Lim, Chaewon Shin, Ji Ye Hwang, Miri Kim, Seung Min Kim, Ha-Neul Jeong, Jin-Woo Jung, Yool-hee Kim, Hyung‐Seok Lee, Ha Young Shin, Eun Bi Hwang, Miju Shin, Carlos Casasnovas, Maria Antònia Albertí Aguiló, Christian Homedes-Pedret, Natalia Juliá Palacios, Laura Diez Porras, Valentina Vélez-Santamaría, A. M. Lázaro, Josep Gamez Carbonell, Pilar Suñé, Maria Salvadó Figueras, Gisela Gili, Gonzalo Mazuela,
Objective To evaluate whether eculizumab helps patients with anti–acetylcholine receptor–positive (AChR+) refractory generalized myasthenia gravis (gMG) achieve the Myasthenia Gravis Foundation of America (MGFA) post-intervention status of minimal manifestations (MM), we assessed patients9 status throughout REGAIN (Safety and Efficacy of Eculizumab in AChR+ Refractory Generalized Myasthenia Gravis) and its open-label extension. Methods Patients who completed the REGAIN randomized controlled trial and continued ...
Lippincott Williams & Wilkins
Henning Andersen, Renato Mantegazza, Jing Jing Wang, Fanny O’Brien, Kaushik Patra, James F. Howard, Claudio Mazia, Miguel Wilken, Fábio Barroso, Juliet Saba, Marcelo Rugiero, Mariela Bettini, Marcelo Chaves, Gonzalo Vidal, Alejandra Dalila Garcia, Jan De Bleecker, Guy Van den Abeele, Kathy de Koning, Katrien De Mey, Rudy Mercelis, Délphine Mahieu, Linda Wagemaekers, Philip Van Damme, Annelies Depreitere, Caroline Schotte, Charlotte Smetcoren, Olivier Stevens, Sien Van Daele, Nicolas Vandenbussche, Annelies Vanhee, Sarah Verjans, Jan Vynckier, Ann D’Hondt, Petra Tilkin, Alzira Alves de Siqueira Carvalho, Igor Dias Brockhausen, David Feder, Daniel Ambrosio, Pamela César, Ana Paula Souto Melo, Renata Martins Ribeiro, Rosana Rocha, Bruno Bezerra Rosa, Thabata Veiga, Luiz Augusto da Silva, Murilo Santos Engel, Jordana Gonçalves Geraldo, Maria da Penha Ananias Morita, Érica Coelho, Gabriel Pina Paiva, M Tovar Pozo, Natalia Prando, Debora Dada Martineli Torres, Cristiani Fernanda Butinhao, Gustavo Duran, Tamires Cristina Gomes da Silva, Luiz Otavio Maia Gonçalves, Lucas Eduardo Pazetto, Tomás Augusto Suriane Fialho, Luciana Renata Cubas Volpe, Luciana Souza Duca, Maurício Friedrich, Alexandre Guerreiro, Henrique Mohr, Maurer Pereira Martins, Daiane da Cruz Pacheco, Luciana Ferreira, Ana Paula Macagnan, Graziela Hünning Pinto, Aline de Cassia Santos, Acary Souza Bullé Oliveira, Ana Carolina Amaral de Andrade, Marcelo Annes, Liene Duarte Silva, Valéria Cavalcante Lino, Wladimir Bocca Vieira de Rezende Pinto, Natália Assis, Fernanda Carrara, Carolina Miranda, Iandra Souza, Ana Patrícia Fernandes, Zaeem A. Siddiqi, Cecile Phan, Jeffrey Narayan, Derrick Blackmore, Ashley Mallon, Rikki Roderus, Elizabeth Watt, Stanislav Voháňka, Josef Bednařík, Magda Chmelikova, Marek Čierny, Stanislava Toncrova, Jana Junkerová, Barbora Kurková, Katarína Reguliová, Olga Zapletalová, Jiří Piťha, Iveta Nováková, Michaela Týblová, Ivana Jurajdova, Marcela Wolfova, Thomas Harbo, Lotte Vinge, Susanne Krogh, Anita Mogensen, John Vissing, Joan Højgaard, Nanna Witting, Anne Ostergaard Autzen, Jane Pedersen, Juha-Pekka Erälinna, Mikko Laaksonen, Olli Oksaranta, Tuula Harrison, Jaana Eriksson, Csilla Rózsa, Melinda Horvath, Gábor Lovas, Judit Matolcsi, G Szabó, Gedeonne Jakab, Brigitta Szabadosne, László Vécsei, Lívia Dézsi, Edina Varga, Monika Konyane, Giovanni Antonini, Antonella Di Pasquale, Matteo Garibaldi, Stefania Morino, Fernanda Troili, Laura Fionda, A Filla, Teresa Costabile, Enrico Marano, Francesco Saccà, Angiola Maria Fasanaro, Angela Marsili, Giorgia Puorro, Carlo Antozzi, Silvia Bonanno, Giorgia Camera, Alberta Locatelli, Lorenzo Maggi, Maria Barbara Pasanisi, Angela Campanella, Amelia Evoli, Paolo Emilio Alboini, Valentina Damato, Raffaele Iorio, Maurizio Inghilleri, Laura Fionda, Vittorio Frasca, Elena Giacomelli, Maria Cristina Gori, Diego Lopergolo, Emanuela Onesti, Vittorio Frasca, Maria Gabriele, Akiyuki Uzawa, Tetsuya Kanai, Naoki Kawaguchi, Masahiro Mori, Yoko Kaneko, Akiko Kanzaki, Eri Kobayashi, Hiroyuki Murai, Katsuhisa Masaki, Dai Matsuse, Takuya Matsushita, Taira Uehara, Misa Shimpo, Maki Jingu, Keiko Kikutake, Yumiko Nakamura, Yoshiko Sano, Kimiaki Utsugisawa, Yuriko Nagane, Ikuko Kamegamori, Tomoko Tsuda, Yuko Fujii, Kazumi Futono, Yukiko Ozawa, Aya Mizugami, Yuka Saito, Hidekazu Suzuki, Miyuki Morikawa, Makoto Samukawa, Sachiko Kamakura, Eriko Miyawaki, Hirokazu Shiraishi, Teiichiro Mitazaki, Masakatsu Motomura, Akihiro Mukaino, Shunsuke Yoshimura, Shizuka Asada, Seiko Yoshida, Shoko Amamoto, Tomomi Kobashikawa, Megumi Koga, Yasuko Maeda, Kazumi Takada, Mihoko Takada, Masako Tsurumaru, Yumi Yamashita, Yasushi Suzuki, Tetsuya Akiyama, Koichi Narikawa, Ohito Tano, Kenichi Tsukita, Rikako Kurihara, Fumie Meguro, Yusuke Fukuda, Miwako Sato, Meinoshin Okumura, Soichiro Funaka, Tomohiro Kawamura, Masayuki Makamori, Masanori Takahashi, Namie Taichi, Tomoya Hasuike, Eriko Higuchi, Hisako Kobayashi, Kaori Osakada, Tomihiro Imai, Emiko Tsuda, Shun Shimohama, Takashi Hayashi, Shin Hisahara, Jun Kawamata, Takashi Murahara, Masaki Saitoh, Shu-Ichiro Suzuki, Daisuke Yamamoto, Yoko Ishiyama, Naoko Ishiyama, Mayuko Noshiro, Rumi Takeyama, Kaori Uwasa, Ikuko Yasuda, Anneke J. van der Kooi, Marianne de Visser, Tamar Gibson, Byung‐Jo Kim, Chang Nyoung Lee, Yong Seo Koo, Hung Youl Seok, Hoo Nam Kang, HyeJin Ra, Byoung Joon Kim, Eun Bin Cho, Misong Choi, HyeLim Lee, Ju‐Hong Min, Jinmyoung Seok, Ji-Eun Lee, Da Yoon Koh, JuYoung Kwon, SangAe Park, Eun Hwa Choi, Yoon‐Ho Hong, Sohyun Ahn, Dae Lim Koo, Jae‐Sung Lim, Chaewon Shin, Ji Ye Hwang, Miri Kim, Seung Min Kim, Ha-Neul Jeong, Jin-Woo Jung, Yool-hee Kim, Hyung‐Seok Lee, Ha Young Shin, Eun Bi Hwang, Miju Shin, Carlos Casasnovas, Maria Antònia Albertí Aguiló, Christian Homedes-Pedret, Natalia Juliá Palacios, Laura Diez Porras, Valentina Vélez-Santamaría, A. M. Lázaro, Exuperio Díez–Tejedor, Pilar Gomez Salcedo, Mireya Fernández-Fournier, Pedro Lopez Ruiz, Francisco Javier Rodríguez de Rivera Garrido, María Sastre, Josep Gámez, Pilar Suñé, María Salvadó, Gisela Gili, Gonzalo Mazuela, Isabel Illa, Elena Cortés Vicente,
To evaluate the effect of eculizumab on perceived fatigue in patients with anti-acetylcholine receptor antibody-positive, refractory, generalized myasthenia gravis (MG) using the Quality of Life in Neurological Disorders (Neuro-QOL) Fatigue subscale, and to evaluate correlations between improvements in Neuro-QOL Fatigue and other clinical endpoints.Neuro-QOL Fatigue, MG Activities of Daily Living (MG-ADL), Quantitative MG (QMG), and the 15-item MG Quality of Life (MG-QOL15) scales were administered during ...
Springer Science+Business Media
Hiroyuki Murai, Akiyuki Uzawa, Yasushi Suzuki, Tomihiro Imai, Hirokazu Shiraishi, Hidekazu Suzuki, Meinoshin Okumura, Fanny O’Brien, Jingjing Wang, Kenji P. Fujita, Kimiaki Utsugisawa, Claudio Mazia, Miguel Wilken, Fábio Barroso, Juliet Saba, Marcelo Rugiero, Mariela Bettini, Marcelo Chaves, Gonzalo Vidal, Alejandra Dalila Garcia, Jan De Bleecker, Guy Van den Abeele, Kathy de Koning, Katrien De Mey, Rudy Mercelis, Délphine Mahieu, Linda Wagemaekers, Philip Van Damme, Annelies Depreitere, Caroline Schotte, Charlotte Smetcoren, Olivier Stevens, Sien Van Daele, Nicolas Vandenbussche, Annelies Vanhee, Sarah Verjans, Jan Vynckier, Ann D’Hondt, Petra Tilkin, Alzira Alves de Siqueira Carvalho, Igor Dias Brockhausen, David Feder, Daniel Ambrosio, Pamela César, Ana Paula Souto Melo, Renata Martins Ribeiro, Rosana Rocha, Bruno Bezerra Rosa, Thabata Veiga, Luiz Augusto da Silva, Murilo Santos Engel, Jordana Gonçalves Geraldo, Maria da Penha Ananias Morita, Érica Coelho, Gabriel Pina Paiva, M Tovar Pozo, Natalia Prando, Debora Dada Martineli Torres, Cristiani Fernanda Butinhao, Gustavo Duran, Tamires Cristina Gomes da Silva, Luiz Otavio Maia Gonçalves, Lucas Eduardo Pazetto, Tomás Augusto Suriane Fialho, Luciana Renata Cubas Volpe, Luciana Souza Duca, Acary Souza Bullé Oliveira, Ana Carolina Amaral de Andrade, Marcelo Annes, Liene Duarte Silva, Valéria Cavalcante Lino, Wladimir Bocca Vieira de Rezende Pinto, Natália Assis, Fernanda Carrara, Carolina Miranda, Iandra Souza, Ana Patrícia Fernandes, Zaeem A. Siddiqi, Cecile Phan, Jeffrey Narayan, Derrick Blackmore, Ashley Mallon, Rikki Roderus, Elizabeth Watt, Jana Junkerová, Barbora Kurková, Katarína Reguliová, Olga Zapletalová, Jiří Piťha, Iveta Nováková, Michaela Týblová, Ivana Jurajdova, Marcela Wolfova, Henning Andersen, Thomas Harbo, Lotte Vinge, Susanne Krogh, Anita Mogensen, John Vissing, Joan Højgaard, Nanna Witting, Anne Mette Ostergaard Autzen, Jane Pedersen, Juha-Pekka Erälinna, Mikko Laaksonen, Olli Oksaranta, Tuula Harrison, Jaana Eriksson, Csilla Rózsa, Melinda Horvath, Gábor Lovas, Judit Matolcsi, G Szabó, Gedeonne Jakab, Brigitta Szabadosne, Giovanni Antonini, Antonella Di Pasquale, Matteo Garibaldi, Stefania Morino, Fernanda Troili, Laura Fionda, A Filla, Teresa Costabile, Enrico Marano, Francesco Saccà, Angiola Maria Fasanaro, Angela Marsili, Giorgia Puorro, Renato Mantegazza, Carlo Antozzi, Silvia Bonanno, Giorgia Camera, Alberta Locatelli, Lorenzo Maggi, Maria Barbara Pasanisi, Angela Campanella, Amelia Evoli, Paolo Emilio Alboini, Valentina Damato, Raffaele Iorio, Tetsuya Kanai, Naoki Kawaguchi, Masahiro Mori, Yoko Kaneko, Akiko Kanzaki, Eri Kobayashi, Katsuhisa Masaki, Dai Matsuse, Takuya Matsushita, Taira Uehara, Misa Shimpo, Maki Jingu, Keiko Kikutake, Yumiko Nakamura, Yoshiko Sano, Yuriko Nagane, Ikuko Kamegamori, Tomoko Tsuda, Yuko Fujii, Kazumi Futono, Yukiko Ozawa, Aya Mizugami, Yuka Saito, Miyuki Morikawa, Makoto Samukawa, Sachiko Kamakura, Eriko Miyawaki, Teiichiro Mitazaki, Masakatsu Motomura, Akihiro Mukaino, Shunsuke Yoshimura, Shizuka Asada, Seiko Yoshida, Shoko Amamoto, Tomomi Kobashikawa, Megumi Koga, Yasuko Maeda, Kazumi Takada, Mihoko Takada, Masako Tsurumaru, Yumi Yamashita, Tetsuya Akiyama, Koichi Narikawa, Ohito Tano, Kenichi Tsukita, Rikako Kurihara, Fumie Meguro, Yusuke Fukuda, Miwako Sato, Soichiro Funaka, Tomohiro Kawamura, Masayuki Makamori, Masanori Takahashi, Namie Taichi, Tomoya Hasuike, Eriko Higuchi, Hisako Kobayashi, Kaori Osakada, Emiko Tsuda, Shun Shimohama, Takashi Hayashi, Shin Hisahara, Jun Kawamata, Takashi Murahara, Masaki Saitoh, Shu-Ichiro Suzuki, Daisuke Yamamoto, Yoko Ishiyama, Naoko Ishiyama, Mayuko Noshiro, Rumi Takeyama, Kaori Uwasa, Ikuko Yasuda, Anneke J. van der Kooi, Marianne de Visser, Tamar Gibson, Carlos Casasnovas, Maria Antònia Albertí Aguiló, Christian Homedes-Pedret, Natalia Juliá Palacios, Laura Diez Porras, Valentina Santamaria, A. M. Lázaro, Exuperio Díez–Tejedor, Pilar Gomez Salcedo, Mireya Fernández-Fournier, Pedro Lopez Ruiz, Francisco Javier Rodríguez de Rivera Garrido, María Sastre, Josep Gámez, Pilar Suñé, María Salvadó, Gisela Gili, Gonzalo Mazuela, Isabel Illa, Elena Cortés Vicente, Jordi Díaz‐Manera, Luis Antonio Querol Gutiérrez, Ricardo Rojas Garcia, Núria Vidal, Elisabet Arribas-Ibar, Fredrik Piehl, Albert Hietala, Lena Bjarbo, İhsan Şükrü Şengün, Arzu Meherremova, Pınar Özçelik, Bengu Balkan, Celal Tuga, Müzeyyen Ugur, Sevim Erdem‐Özdamar, Can Ebru Bekircan‐Kurt, Nazire Pınar Acar, Ezgi Yılmaz, Yagmur Caliskan, Gulsah Orsel, Hüsnü Efendi, S. Aydınlık, Hakan Çavuş, Ayşe Kutlu, Gulsah Becerikli, Cansu Semiz, Ozlem Tun, Murat Terzi, Baki Doğan, Musa Onar, Sedat Şen, Tugce Kirbas Cavdar, Adife Veske, Fiona Norwood, Aikaterini Dimitriou, Jakit Gollogly, Mohamed Mahdi‐Rogers, Arshira Seddigh, Giannis Sokratous, Gal Maier, Faisal Sohail, Saiju Jacob, Girija Sadalage, Pravin Torane, Claire Brown, Amna Shah, Sivakumar Sathasivam, Heike Arndt, Debbie Davies, Dave Watling, Anthony Amato, Tom Cochrane, Mohammed Salajegheh, Kristen Roe, Katherine Amato, Shirli Toska, Gil I. Wolfe, Nicholas J. Silvestri, Kara Patrick, Karen Zakalik,
The terminal complement inhibitor eculizumab was shown to improve myasthenia gravis-related symptoms in the 26-week, phase 3, randomized, double-blind, placebo-controlled REGAIN study (NCT01997229). In this 52-week sub-analysis of the open-label extension of REGAIN (NCT02301624), eculizumab's efficacy and safety were assessed in 11 Japanese and 88 Caucasian patients with anti-acetylcholine receptor antibody-positive refractory generalized myasthenia gravis. For patients who had received placebo during ...
Elsevier BV
Valentina Vélez-Santamaría, Edgard Verdura, Colleen Macmurdo, Laura Planas‐Serra, Agatha Schlüter, Josefina Casas, Juan José Martínez, Carlos Casasnovas, Yue Si, Stephanie S Thompson, Reza Maroofian, Aurora Pujol,
... investing in your future (Rio Hortega, CM18/00145; Sara Borrell, CD19/00221; PFIS, FI18/00141)
Tópico(s): RNA modifications and cancer
2020 - Oxford University Press | Brain
James F. Howard, Kimiaki Utsugisawa, Michael Benatar, Hiroyuki Murai, Richard J. Barohn, Isabel Illa, Saiju Jacob, John Vissing, Ted M. Burns, John T. Kissel, Srikanth Muppidi, Richard J. Nowak, Fanny O’Brien, Jingjing Wang, Renato Mantegazza, Claudio Mazia, Miguel Wilken, Carolina Ortea, Juliet Saba, Marcelo Rugiero, Mariela Bettini, Gonzalo Vidal, Alejandra Dalila Garcia, Phillipa J. Lamont, Wai Yie Leong, Heidi Boterhoven, Beverly Fyfe, L. Jackson Roberts, Mahi Jasinarachchi, Natasha Willlems, Julia Wanschitz, Wolfgang N. Löscher, Jan De Bleecker, Guy Van den Abeele, Kathy de Koning, Katrien De Mey, Rudy Mercelis, Linda Wagemaekers, Délphine Mahieu, Philip Van Damme, Charlotte Smetcoren, Olivier Stevens, Sarah Verjans, Ann D’Hondt, Petra Tilkin, Alzira Alves de Siqueira Carvalho, Rosa Hasan, Igor Dias Brockhausen, David Feder, Daniel Ambrosio, Ana Paula Souto Melo, Rosana Rocha, Bruno Bezerra Rosa, Thabata Veiga, Luiz Augusto da Silva, Jordana Gonçalves Geraldo, Maria da Penha Morita Ananias, Érica Coelho, Gabriel Pina Paiva, M Tovar Pozo, Natalia Prando, Debora Dada Martineli Torres, Cristiani Fernanda Butinhao, Érica Coelho, Luciana Renata Cubas Volpe, Gustavo Duran, Tamires Cristina Gomes da Silva, Luiz Otavio Maia Gonçalves, Lucas Eduardo Pazetto, Luciana Souza Duca, Tomás Augusto Suriane Fialho, Maurício Friedrich, Alexandre Guerreiro, Henrique Mohr, Maurer Pereira Martins, Daiane da Cruz Pacheco, Ana Paula Macagnan, Aline de Cassia Santos, Acary Souza Bullé Oliveira, Ana Carolina Amaral de Andrade, Marcelo Annes, Valéria Cavalcante Lino, Wladimir Bocca Vieira de Rezende Pinto, Carolina Miranda, Fernanda Carrara, Iandra Souza, Angela Genge, Rami Massie, Natasha Campbell, Vera Bril, Hans Katzberg, Mehran Soltani, Eduardo Ng, Zaeem A. Siddiqi, Celile Phan, Derrick Blackmore, Stanislav Voháňka, Josef Bednařík, Magda Chmelikova, Marek Čierny, Stanislava Toncrova, Jana Junkerová, Barbora Kurková, Katarína Reguliová, Olga Zapletalová, Jiří Piťha, Iveta Nováková, Michaela Týblová, Marcela Wolfova, Ivana Jurajdova, Henning Andersen, Thomas Harbo, Lotte Vinge, Anita Mogensen, Joan Højgaard, Nanna Witting, Anne Mette Ostergaard Autzen, Jane Pedersen, Martti Färkkilâ, Sari Atula, Anne Nyrhinen, Juha-Pekka Erälinna, Mikko Laaksonen, Olli Oksaranta, Jaana Eriksson, Tuula Harrison, Claude Desnuelle, Sabrina Sacconi, Marie‐Hélène Soriani, Sonia Decressac, Julie Moutarde, Pauline Lahaut, Guilhem Solé, Gwendal Le Masson, Anne-Cécile Wielanek-Bachelet, Morgane Gaboreau, Caroline Moreau, Amy Wilson, Christophe Vial, Françoise Bouhour, H. Gervais-Bernard, H Merle, Caroline Hourquin, Arnaud Lacour, Olivier Outteryck, Patrick Vermersch, Hélène Zéphir, Edouard Millois, Michel Deneve, Fabienne Deruelle, Benedikt Schoser, Stephan Wenninger, Martin Stangel, Sascha Alvermann, Stefan Gingele, Thomas Skripuletz, Kurt-Wolfram Suehs, Corinna Trebst, Karin Fricke, Sotirios Papagiannopoulos, Sevasti Bostantzopoulou, Nicholas Vlaikidis, Martha Zampaki, Nikoletta Papadopoulou, Dimos D. Mitsikostas, Eleni Kasioti, Efstathia Mitropoulou, Despoina Charalambous, Csilla Rózsa, Melinda Horvath, Gábor Lovas, Judit Matolcsi, G Szabó, Brigitta Szabadosne, László Vécsei, Lívia Dézsi, Edina Varga, Monika Konyane, Bella Gross, Olga Azrilin, Nelly Greenbereg, H Kuperman, Giovanni Antonini, Matteo Garibaldi, Stefania Morino, Fernanda Troili, Antonella Di Pasquale, Alessandro Filla, Teresa Costabile, Enrico Marano, Francesco Saccà, Angela Marsil, Giorgia Puorro, Michelangelo Maestri Tassoni, Anna De Rosa, Silvia Bonanno, Carlo Antozzi, Lorenzo Maggi, Angela Campanella, C. Angelini, Paola Cudia, Valentina Pegoraro, Elena Pinzan, Francesca Bevilacqua, D. Orrico, Domenico Marco Bonifati, Amelia Evoli, Paolo Emilio Alboini, Valentina Damato, Raffaele Iorio, Maurizio Inghilleri, Laura Fionda, Vittorio Frasca, Elena Giacomelli, Maria Cristina Gori, Diego Lopergolo, Emanuela Onesti, Maria Gabriele, Francesco Patti, Andrea Caramma, Silvia Messina, Ester Reggio, Cinzia Caserta, Akiyuki Uzawa, Tetsuya Kanai, Masahiro Mori, Yoko Kaneko, Akiko Kanzaki, Eri Kobayashi, Katsuhisa Masaki, Dai Matsuse, Takuya Matsushita, Taira Uehara, Misa Shimpo, Maki Jingu, Keiko Kikutake, Yumiko Nakamura, Yoshiko Sano, Yuriko Nagane, Ikuko Kamegamori, Yuko Fujii, Kazumi Futono, Tomoko Tsuda, Yuka Saito, Hidekazu Suzuki, Miyuki Morikawa, Makoto Samukawa, Sachiko Kamakura, Hirokazu Shiraishi, Teiichiro Mitazaki, Masakatsu Motomura, Akihiro Mukaino, Shunsuke Yoshimura, Shizuka Asada, Tomomi Kobashikawa, Megumi Koga, Yasuko Maeda, Kazumi Takada, Mihoko Takada, Yumi Yamashita, Seiko Yoshida, Yasushi Suzuki, Tetsuya Akiyama, Koichi Narikawa, Kenichi Tsukita, Fumie Meguro, Yusuke Fukuda, Miwako Sato, Hidenori Matsuo, Takayasu Fukudome, Yuichiro Gondo, Yasuhiro Maeda, Akiko Nagaishi, Shunya Nakane, Yoshinori Okubo, Meinoshin Okumura, Soichiro Funaka, Tomohiro Kawamura, Masayuki Makamori, Masanori Takahashi, Tomoya Hasuike, Eriko Higuchi, Hisako Kobayashi, Kaori Osakada, Namie Taichi, Emiko Tsuda, Takashi Hayashi, Shin Hisahara, Tomihiro Imai, Jun Kawamata, Takashi Murahara, Masaki Saitoh, Shun Shimohama, Shu-Ichiro Suzuki, Daisuke Yamamoto, Shingo Konno,
Complement is likely to have a role in refractory generalised myasthenia gravis, but no approved therapies specifically target this system. Results from a phase 2 study suggested that eculizumab, a terminal complement inhibitor, produced clinically meaningful improvements in patients with anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis. We further assessed the efficacy and safety of eculizumab in this patient population in a phase 3 trial.We did a phase 3, ...
Elsevier BV
Ruth Garzón, Silvia F. Soriano, José Miguel Rodríguez‐Frade, Lucio Gómez, Ana Martı́n de Ana, Myriam Sánchez-Gómez, Carlos Martínez‐A, Mario Mellado,
... culture supernatants (23Bleul C.C. Fuhlbrigge R.C. Casasnovas J.M. Aiuti A. Springer T.A. J. ... was used as tracer (34Bang P. Eriksson U. Sara V. Wivall I.L. Hall K. Acta Endocrinol. ( ...
Tópico(s): Immune Cell Function and Interaction
2004 - Elsevier BV | Journal of Biological Chemistry
Roberto Bejarano Arosemena, Iago Sousa Casasnovas, Miriam Juàrez Fernández, Manuel Martínez‐Sellés, Sara Álvarez Zaballos, Esteban González Torrecilla, Felipe Atienza, Alejandro Carta Bergaz, Ángel Arenal, Francisco Fernández‐Avilés, Pablo Ávila,
Tópico(s): Cardiac pacing and defibrillation studies
2023 - Elsevier BV | Revista Española de Cardiología
R Sánchez, Jorge Martínez-Solano, Jorge García Carreño, Iago Sousa Casasnovas, Miriam Juàrez Fernández, Roberto Bejarano Arosemena, L. Gómez Pérez, Sara Álvarez Zaballos, Ricardo Sanz Ruíz, Enrique Gutiérrez, Jaime Elízaga Corrales, Francisco Fernández‐Avilés, Javier Bermejo Thomas, Manuel Martínez‐Sellés,
Tópico(s): Cardiovascular Effects of Exercise
2023 - Elsevier BV | Revista Española de Cardiología
Erola Pairo‐Castineira, Konrad Rawlik, Andrew D. Bretherick, Ting Qi, Yang Wu, Isar Nassiri, Glenn A. McConkey, Marie Zechner, Lucija Klarić, Fiona Griffiths, Wilna Oosthuyzen, Athanasios Kousathanas, Anne Richmond, Jonathan Millar, Clark D Russell, Tomas Malinauskas, Ryan S. Thwaites, Kirstie Morrice, Seán Keating, David M. Maslove, Alistair Nichol, Malcolm G. Semple, Julian C. Knight, Manu Shankar‐Hari, Charlotte Summers, Charles Hinds, Peter Horby, Lowell Ling, Daniel F. McAuley, Hugh Montgomery, Peter Openshaw, Colin B. Begg, Timothy Walsh, Albert Tenesa, Carlos Flores, José A. Riancho, Augusto Rojas‐Martínez, Pablo Lapunzina, Sara Clohisey, Johnny Millar, Manu Shankar‐Hari, Emma Aitkin, Latha Aravindan, Ruth Armstrong, J. Kenneth Baillie, Heather Biggs, Ceilia Boz, Adam Brown, Primmy Chikowore, Richard Clark, Audrey Coutts, J. Terrence Coyle, Louise Cullum, Sukamal Das, Nicky Day, Lorna Donnelly, Esther Duncan, Paul Finernan, Max Head Fourman, Anita Furlong, James Furniss, Bernadette Gallagher, Tammy Gilchrist, Ailsa Golightly, Fiona Griffiths, Katarzyna Hafezi, Debbie Hamilton, Ross Hendry, Naomi Kearns, Dawn Law, R. M. Law, Sarah Law, Rebecca Lidstone-Scott, Christen Lauder, Louise MacGillivray, Alan Maclean, Hanning Mal, Sarah McCafferty, Ellie Mcmaster, Jen Meikle, Shona C. Moore, Sheena Murphy, Hellen Mybaya, Miranda Odam, Wilna Oosthuyzen, Chenqing Zheng, Jiantao Chen, Nick Parkinson, Trevor Paterson, Petra Tucker, Katherine Schon, Andrew Stenhouse, Mihaela Das, Maaike Swets, Helen Szoor-McElhinney, Filip Taneski, Lance Turtle, Tony Wackett, Mairi Ward, Jane Weaver, Nicola Wrobel, Marie Zechner, Jacqueline Pan, Neus Grau, Tim Jones, Rosario Lim, Martina Marotti, R. Chris Whitton, Aneta Bociek, Sara Campos, Gill Arbane, Manu Shankar‐Hari, Marlies Ostermann, Mina Cha, Fabiola DAmato, Eirini Kosifidou, Shelley Lorah, Kyma Morera, Sarah Bircham, Laura Brady, Keith Hugill, Jeremy Henning, Stephen Bonner, Evie Headlam, Jessica Jones, A. List, J Morley, Amy Welford, Bobette Kamangu, Anitha Ratnakumar, Abiola Shoremekun, Zoe Alldis, Raine Astin-Chamberlain, Fatima Bibi, Jack Biddle, Sarah Blow, Matthew L. Bolton, Catherine Borra, Ruth Bowles, Maudrian Burton, Yasmin Choudhury, Amber Cox, Amy Easthope, Patrizia Ebano, Stavros Fotiadis, Jana Gurasashvili, Rosslyn Halls, Pippa Hartridge, Delordson Kallon, Jamila Kassam, Ivone Lancoma-Malcolm, Maninderpal Matharu, P. May, Oliver Mitchelmore, Tabitha Newman, Mital Patel, Jane Pheby, Irene Pinzuti, Zoe Prime, Oleksandra Prysyazhna, Julian Shiel, Melanie Taylor, Carey Tierney, Olivier Zongo, S. M. Wood, Anne Zak, David Collier, Manuela Mundy, C. C. Thompson, Lisa Pritchard, Minnie Gellamucho, David Cartlidge, Nageswar Bandla, Lucy Bailey, Michelle Davies, Jane Delaney, Leanne Scott, Marwa Abdelrazik, Frater Alasdair, David Carter, Munzir Elhassan, Arunkumar Ganesan, Samuel Jenkins, Zoe Lamond, Dharam Purohit, Kumar Rohit, Malik Saleem, Alanna Wall, Kugan Xavier, Dhanalaksmi Bakthavatsalam, Kirolos Gehad, Pakeerathan Gnanapragasam, Kapil Jain, Swati Jain, Abdul Malik, Naveen Pappachan, Jerónimo Moreno-Cuesta, Anne Haldeos, Rachel Vincent, Maryjane Oziegb, Anna Cavazza, Maeve Cockrell, Eleanor Corcoran, Maria Depante, Clare Finney, Ellen Jerome, Abigail Knighton, Monalisa Nayak, Evita Pappa, Rohit Saha, Sian Saha, Andrew Dodd, Kevin O’Reilly, Mark McPhail, Emma Clarey, Harriet Noble, John Smith, Phoebe Coghlan, Stephen J. Brett, Anthony Gordon, Maie Templeton, David Antcliffe, Dorota Banach, Sarah Darnell, Ziortza Fernandez, Eleanor Jepson, Amal Mohammed, Roceld Rojo, Sonia Sousa Arias, Anita Gurung, Jenny Wong, Jaime Fernandez-Roman, David Hamilton, Emily Johnson, Brian Johnston, Maria Lopez Martinez, Suleman Mulla, Alicia Waite, Karen Williams, Victoria Waugh, Ingeborg Welters, Jessica Emblem, Maria Norris, David Shaw, Archana Bashyal, Sally Beer, Paula Hutton, Stuart McKechnie, Neil Davidson, Soya Mathew, Grace Readion, Jung Hee Ryu, Jean Amos Wilson, Shruti Agrawal, Kay Elston, Megan Jones, Eoghan Meaney, Petra Polgarova, Muhammad Elbehery, Charlotte Summers, Esther Daubney, Anthony Ng, Jocelyn R. Marshall, Nazima Pathan, Katerina Stroud, Deborah L. White, Angela Andrew, Saima Ashraf, Amy Clark, Martin Dent, Margaret Langley, Cecilia Peters, Lucy Ryan, Julia Sampson, Shuying Wei, Alice Baddeley, Megan Meredith, Lucy Morris, Alexandra Gibbons, Lisa McLoughlin, Carlos Castro Delgado, Victoria Clark, Deborah Dawson, Lijun Ding, Georgia Durrant, Obiageri Ezeobu, Abiola Harrison, William James Hurt, Rebecca Kanu, Ashley Kinch, Susannah Leaver, Ana Lisboa, Jisha Mathew, Kamal Patel, Romina Pepermans Saluzzio, John Rawlins,
Nature Portfolio