James Landale, James Bone and Eve-Ann Prentice, S. Goldman, Anthony Harris, Liz Dolan, Bernard McCarthy, Jon Ashworth, Alan Hamilton and John Young, Nick Nuttall, Andrew Pierce, Mark Huband, Patricia Davies, Alexandra Frean, Rob Hughes, Rose Wild, Simon Barnes, Richard Ford, Home Correspondent, Gillian Wolfe, Jane MacQuitty, Bill Frost, Andrew Longmore, Ronald Faux, Peter Springett, Janet Bush, Economics Correspondent, John Diamond, Richard Lamb, Ivo Tennant, Philip Howard, Susan Bell, Ali, Paul Massey, Michael Binyon, Jeremy Kingston, Brian Pedley, George Sivell, Clive Fewins, Carl Mortished, Morag Preston, Tony Patrick, Stewart Tendler, Crime Correspondent, Kevin Eason, Geoff Brown, Mary Gunton, Hugh Cubitt, Jonathan Eyal, Martin Fletcher, Pat Gibson, John Alkin, Robert Sheehan, John Hopkins, Golf Correspondent, Peter Ball, Ruth Gledhill, Jean-Pierre Camelot, Rachel Kelly, Michael J. Cowie, Ruth Gledhill Religion Correspondent, F. J. Sharpless, Kathleen Adams, Alan Hamilton, Daniel Johnson, Peter Millar, Douglas Brewer, Neville Goldrein, Lord Montagu of Beaulieu, Nicholas Watt, Jenny MacArthur, A. Mackie, John Young, Harry Ritchie, Frances Bissell, Joseph Connolly, Sarah Bagnall, Peter Barnard, Nigella Lawson, Edward Gorman, Derwent May, Mary Loudon, Nick Nuttall and Marianne Curphey, Brian Nicholson, Russell Kempson, A. H. Bates, Richard Cork, Stephen Anderton, Lindsay Cook, Michael Theodoulou, David Miller, Gabriella Gamini, Jill Insley, Kate Adie, Geoffrey Wheeler, Liz Dolan and Morag Preston, Christina Koning, Albert Friedlander, Dalya Alberge, Arts Correspondent, David Powell Athletics Correspondent, Raymond Keene, Vaughan Freeman, David Robinson, Philip Willan, P. H. S, Christine Buckley and Jonathan Prynn, David Powell and David Miller, Don Lee, Richard Evans, Caroline Merrell, Alan Hadfield, Miss Caroline Waring, Eric Reguly, Oliver Holt, Marcel Berlins, Roger Boyes, Nigel Hawkes, Science Editor, Kate Alderson, Dalya Alberge, G. Dodds, Julian Muscat, Richard Duce, Martin Waller, Deputy City Editor, Anne Ashworth, Agence France-Presse, Sara McConnell, Ian Orr-Ewing, Alan Copps, Sean Coughlan, John Byfield, Valerie Singleton, Lucille Grant, Tim Wapshott, Helen Mound, Christine Wheeler, Ben MacIntyre, Paul Barker, Nigel Boothman, Alan Lee Cricket Correspondent, Richard Beeston, Russell Twisk, Tony Dawe, Simon Jenkins, Philip Pangalos, Michael Binyon, Diplomatic Editor, Anne Ashworth Personal Finance Editor, Martin Waller, Kate Bassett, Peter Ingham, Jason McDonald, Peter James, Tom Rhodes, Mrs J. McFarlane, Marianne Curphey, Jill Sherman, Political Correspondent, Adrian Dence, Jonathan Meades, David Powell, Jack Bailey, Richard Morrison, Elizabeth Buchan, Eric Alley, Michael Henderson, Anne McElvoy, Jan Brown, Alan Jackson, Penny Perrick, Dr Dashboard, Josh Lewis, Richard Ford, Christopher Irvine, Melvyn Marckus,
... Retired couple must demolish £75,000 home Villa Montes Phones Direct Football hooligans face tighter controls Father ... Send your money out… Pitfalls of leasehold conversion Sara McConnell warns of the obstacles to winning a ...
1995 - Gale Group | TDA
Roberto Velasco, Juan Trujillo, José Fernández-Arribas, Beatriz Serrano, Nathalie Campo-Fernández, Sara Puente‐Montes,
We studied 140 febrile infants between 30 and 90 days of age who had a positive urine culture to analyze the risk for complications. Patients with a healthy appearance and C-reactive protein blood value less than 40 mg/L had a very small probability of complications.
Tópico(s): Urological Disorders and Treatments
2012 - Lippincott Williams & Wilkins | The Pediatric Infectious Disease Journal
Roberto Velasco, José Luis Fernández Arribas, Sara Puente Montes, María Natalí Campo Fernández, Carmelo Gutiérrez Abad, Leticia Gonzalez Martin, M. González Sagrado,
Acute appendicitis is the most common surgical emergency during childhood. Accurate early diagnosis is important to avoid complications and unnecessary interventions. In 2002, Samuel developed the Pediatric Appendicitis Score (PAS) based on a series of data obtained from anamnesis, physical examination, and laboratory tests. The main purpose of this study was to check the validity of PAS and its applicability to our population.Prospective observational study, carried out at Hospital Río Hortega (Valladolid, ...
Tópico(s): Intraperitoneal and Appendiceal Malignancies
2012 - Lippincott Williams & Wilkins | Pediatric Emergency Care
Daniele Mipatrini, Sebastiano Pollina Addario, Roberto Bertollini, Mario Palermo, Alice Mannocci, Giuseppe La Torre, K. Langley, Matteo Dembech, Sara Barragán Montes, Santino Severoni,
Access to healthcare services for undocumented migrants is one of the main public health issues currently being debated among European countries. Exclusion from primary healthcare services may lead to serious consequences for migrants' health. We analyzed the risk among undocumented migrants, in comparison with regular migrants, of being hospitalized for preventable conditions in the Region of Sicily (Italy). We performed a hospital-based cross-sectional study of the foreign population hospitalized ...
Tópico(s): Chronic Disease Management Strategies
2017 - Oxford University Press | European Journal of Public Health
Sara M. C. Monte, V. Infante, J.F.A. Madeira, F. Moleiro,
This article is devoted to the study of the optimal design of fibers orientation in a composite specimen with the objective to minimize the displacement. The composite specimen considered is within the scope of aerospace and mechanical applications. The objective function associated with the composite design is computed based on a static analysis of a finite element solid model, which allows one to define (or control) the fibers orientation. The recent global and local optimization using direct search ...
Tópico(s): Structural Analysis and Optimization
2016 - Taylor & Francis | Mechanics of Advanced Materials and Structures
M. Belén Rubio, Sara Domínguez, Enrique Monte, Rosa Hermosa,
Trichoderma spp. are widely used as biopesticides and biofertilizers to control diseases and to promote positive physiological responses in plants. In vitro and in vivo assays with Trichoderma harzianum CECT 2413 (T34), Trichoderma virens Gv29-8 (T87) and Trichoderma hamatum IMI 224801 (T7) revealed that these strains affected the growth and development of lateral roots in tomato plants in different ways. The early expression profiles of these Trichoderma strains were studied after 20 h of incubation ...
Tópico(s): Studies on Chitinases and Chitosanases
2011 - Microbiology Society | Microbiology
Rosie Mayston, Mariella Guerra, Yueqin Huang, Ana Luisa Sosa, Richard Uwakwe, Isaac Acosta, Peter Ezeah, Sara Gallardo, Verónica Montes de, Hong Wang, Maëlenn Guerchet, Zhaorui Liu, Maria Angélica Sanchez, Peter Lloyd‐Sherlock, Martin Prince,
In low or middle income countries chronic diseases are rapidly becoming the main cause of disease burden. However, the main focus of health policymakers has been on preventing death from cancer and heart disease, with very little attention to the growing problem of long-term needs for care (dependence). Numbers of dependent older people are set to quadruple by 2050. The economic impact of providing long-term care is likely to be substantial. The study uses mixed methods and draws on and extends the ...
Tópico(s): Global Health Care Issues
2014 - Springer International Publishing | SpringerPlus
M. Belén Rubio, Narciso M. Quijada, Esclaudys Pérez, Sara Domínguez, Enrique Monte, Rosa Hermosa,
ABSTRACT Trichoderma parareesei and Trichoderma reesei (teleomorph Hypocrea jecorina ) produce cellulases and xylanases of industrial interest. Here, the anamorphic strain T6 (formerly T. reesei ) has been identified as T. parareesei , showing biocontrol potential against fungal and oomycete phytopathogens and enhanced hyphal growth in the presence of tomato exudates or plant cell wall polymers in in vitro assays. A Trichoderma microarray was used to examine the transcriptomic changes in T6 at 20 h of interaction ...
Tópico(s): Nematode management and characterization studies
2014 - American Society for Microbiology | Applied and Environmental Microbiology
Octavian O. H. Stephan, Stéphanie Cottier, Sara Fahlén, Adriana Montes‐Rodriguez, Jia Sun, D. Magnus Eklund, Ulrich Klahre, Benedikt Kost,
Abstract RAC/ROP GTPases coordinate actin dynamics and membrane traffic during polar plant cell expansion. In tobacco (Nicotiana tabacum), pollen tube tip growth is controlled by the RAC/ROP GTPase RAC5, which specifically accumulates at the apical plasma membrane. Here, we describe the functional characterization of RISAP, a RAC5 effector identified by yeast (Saccharomyces cerevisiae) two-hybrid screening. RISAP belongs to a family of putative myosin receptors containing a domain of unknown function ...
Tópico(s): Photosynthetic Processes and Mechanisms
2014 - Oxford University Press | The Plant Cell
Produção Nacional
Revisado por pares
Rocio Victoria Gili, Sara Leeson, Evelyn Montes-Chañi, Daniel Xutuc, Ismael Alejandro Contreras-Guillén, Gerardo N. Guerrero-Flores, Márcia Cristina Teixeira Martins, Fabio J. Pacheco, Sandaly Oliveira da Silva Pacheco,
Although current research has contributed to the promotion of whole-food plant-based diets, few studies have examined healthy vegan dietary and lifestyle factors, especially in South America. Therefore, we aimed at investigating the adherence to healthy vegan lifestyle habits among Argentinian vegetarians and omnivorous, using a recently developed vegetarian lifestyle index adapted to the vegan dietary pattern. Also, accessibility of vegetarian foods, and the proportion of household income spent ...
Tópico(s): Nutritional Studies and Diet
2019 - Multidisciplinary Digital Publishing Institute | Nutrients
Sara Gullace, Verónica Montes‐García, Víctor F. Martín, David Larios, Valentina Girelli Consolaro, F. Obelleiro, Giuseppe Calogero, Stefano Casalini, Paolo Samorı́,
Abstract The development of novel, highly efficient, reliable, and robust surface enhanced Raman scattering (SERS) substrates containing a large number of hot spots with programmed size, geometry, and density is extremely interesting since it allows the sensing of numerous (bio‐)chemical species. Herein, an extremely reliable, easy to fabricate, and label‐free SERS sensing platform based on metal nanoparticles (NPs) thin‐film is developed by the layer‐by‐layer growth mediated by polyelectrolytes. A ...
Tópico(s): Advanced Nanomaterials in Catalysis
2021 - Wiley | Small
Laura Martínez‐Arias, Sara Panizo, Cristina Alonso‐Montes, Julia Martín-Vírgala, Beatriz Martín-Carro, Sara Fernández-Villabrille, Carmen García Gil-Albert, Carmen Palomo-Antequera, José Luis Fernández Martín, María Piedad Ruiz‐Torres, Adriana Dusso, Natalia Carrillo‐López, Jorge B. Cannata‐Andía, Manuel Naves‐Díaz,
In chronic kidney disease, the activation of the renin-angiotensin-aldosterone system (RAAS) and renal inflammation stimulates renal fibrosis and the progression to end-stage renal disease. The low levels of vitamin D receptor (VDR) and its activators (VDRAs) contribute to worsen secondary hyperparathyroidism and renal fibrosis.The 7/8 nephrectomy model of experimental chronic renal failure (CRF) was used to examine the anti-fibrotic effects of treatment with two VDRAs, paricalcitol and calcitriol, ...
Tópico(s): Electrolyte and hormonal disorders
2020 - Oxford University Press | Nephrology Dialysis Transplantation
Agostina Stradella, Jesús Del Valle, Paula Rofes, Gardenia Vargas‐Parra, Mònica Salinas, Sara González, Eva Montes, Adriana López‐Doriga, Carolina de la Torre, Rafael de Cid, Esther Darder, Àlex Teulé, Ares Solanes, Elisabet Munté, Gabriel Capellá, Marta Pineda, Lídia Feliubadaló, Joan Brunet, Conxi Lázaro,
Background Hereditary breast and ovarian cancer syndrome (HBOC) is an inherited disorder with an increased risk of breast cancer (BC) and ovarian cancers (OC). Mutations in BRCA1-BRCA2 explains less than a half of cases. In the last decade several genes with different penetrance have been associated with an increased risk of BC or OC. A recurrent heterozygous ERCC3 truncating mutation increases the risk for breast cancer in patients with Ashkenazi Jewish ancestry. Our study aimed to investigate the ...
Tópico(s): Genomic variations and chromosomal abnormalities
2020 - Elsevier BV | European Journal of Cancer
Pedro R. Gil‐Monte, Sara Unda Rojas, Jorge I. Sandoval Ocaña,
SUMMARY Since the term burnout began to be used in the mid 1970’s to refer to the process of deterioration in the care and professional attention given to users of human service organizations (public service, volunteer, medical, human social service, educational organizations, etc.), a variety of instruments have been developed to measure this phenomenon. A review of the literature makes it possible to conclude that among these measurement instruments the Maslach Burnout Inventory (MBI) has been used ...
Tópico(s): Workplace Health and Well-being
2009 - Ramon de la Fuente National Institute of Psychiatry | Salud Mental
Sara Pignatelli, Paola Dal Monte, Giada Rossini, Tiziana Lazzarotto, Maria Rosaria Gatto, Maria Paola Landini,
Human cytomegalovirus (HCMV) clinical isolates display genetic polymorphisms, supposed to be related with strain-specific tissue-tropism and HCMV-induced immunopathogenesis. One recently discovered polymorphic gene is ORF UL73, encoding for the envelope glycoprotein gN. Among HCMV clinical strains, it shows four distinct genomic variants denoted as gN-1, gN-2, gN-3 and gN-4.Aims of this study were to assess the prevalence of the different gN types in the populations examined and to investigate the ...
Tópico(s): Herpesvirus Infections and Treatments
2002 - Elsevier BV | Journal of Clinical Virology
Paola Dal Monte, Sara Pignatelli, Nicoletta Zini, N. M. Maraldi, Emmanuelle Perret, M.C. Prévost, Maria Paola Landini,
Human cytomegalovirus (HCMV) UL53 belongs to a family of conserved herpesvirus genes. In this work, the expression and localization of the UL53 gene product was analysed. Results obtained showed that pUL53 is a new structural protein. In infected human fibroblasts, pUL53 localizes in cytoplasmic perinuclear granular formations together with other structural viral proteins. In the nucleus, pUL53 forms patches at the nuclear periphery and co-localizes with lamin B at the internal nuclear membrane level. ...
Tópico(s): Virus-based gene therapy research
2002 - Microbiology Society | Journal of General Virology
Sara Pignatelli, Paola Dal Monte, Giada Rossini, Szu‐Yi Chou, Takashi Gojobori, Kousuke Hanada, Jin Guo, William D. Rawlinson, William J. Britt, Michael Mach, Maria Paola Landini,
Human cytomegalvirus (HCMV) ORF UL73 is a polymorphic locus, encoding the viral glycoprotein gpUL73-gN, a component of the gC-II envelope complex. The previously identified gN genomic variants, denoted gN-1, gN-2, gN-3 and gN-4, were further investigated in this work by analysing a large panel of HCMV clinical isolates collected from all over the world (223 samples). Sequencing and phylogenetic analysis confirmed the existence of the four gN genotypes, but also allowed the identification of a novel ...
Tópico(s): HIV Research and Treatment
2003 - Microbiology Society | Journal of General Virology
Bruce J. MacFadden, Michael X. Kirby, Aldo F. Rincón, Camilo Montes, Sara Morón, N. Strong, Carlos Jaramillo,
Recently collected specimens of the extinct tayassuine peccary “Cynorca” occidentale (and another indeterminant tayassuid) are described from new excavations along the southern reaches of the Panama Canal. Fossil peccaries were previously unknown from Panama, and these new tayassuid specimens therefore add to the extinct mammalian biodiversity in this region. “Cynorca” occidentale occurs in situ in the Centenario Fauna (new name) from both the upper part of the Culebra Formation and overlying Cucaracha ...
Tópico(s): Pleistocene-Era Hominins and Archaeology
2010 - Cambridge University Press | Journal of Paleontology
Julio Fernández‐Mendoza, Christina Ilioudi, María Isabel Montes, Sara Olavarrieta‐Bernardino, Acacia Aguirre-Berrocal, Juan J. de la Cruz, Antonio Vela‐Bueno,
Tópico(s): Sleep and Wakefulness Research
2010 - Springer Science+Business Media | Sleep and Biological Rhythms
María Dulfary Sánchez, Yoenis García, Carlos Montes, Sara París, Mauricio Rojas, Luis F. Barrera, Mauricio A. Arias, Luis F. García,
Alterations of monocyte/macrophages have been reported in patients with tuberculosis (TB), but their significance is poorly understood. Blood mononuclear cells from patients with different clinical forms of TB, at various times of anti-TB treatment, and healthy tuberculin positive individuals, were double-stained for CD14 plus CD206, TLR-2, IFN-γR1, CD40, HLA-DR, CD36 and CD163, and analyzed by flow cytometry. Monocytes were infected with Mycobacterium tuberculosis H37Rv and 24 h later the phenotype, ...
Tópico(s): Tuberculosis Research and Epidemiology
2006 - Elsevier BV | Microbes and Infection
Marcela I. Henao, Carlos Montes, Sara París, Luis F. García,
Tuberculosis (TB) has different clinical presentations. Pulmonary TB affects only the lungs and exhibits variable anti-mycobacterial immune responses. Pleural TB is a localized disease with a strong immune response. Miliary TB is a disseminated form with poor immune response. Cytokines play a pivotal role in anti-mycobacterial response and may determine the type of TB. Thus, gene polymorphisms associated with cytokine production may be associated with clinical presentations of TB. In this study, ...
Tópico(s): Immunodeficiency and Autoimmune Disorders
2005 - Elsevier BV | Tuberculosis
Giada Rossini, Sara Pignatelli, Paola Dal Monte, Daria Camozzi, Tiziana Lazzarotto, Liliana Gabrielli, Maria Rosaria Gatto, Maria Paola Landini,
Human cytomegalovirus (HCMV) ORF UL73 encodes the envelope glycoprotein gpUL73-gN, which shows seven genotypes (gN-1, gN-2, gN-3a, gN-3b, gN-4a, gN-4b, gN-4c). The goal of this study was to determine retrospectively the distribution of gN variants in solid organ transplant recipients with HCMV infection and to establish an association with parameters important for monitoring post-transplantation clinical course during a follow-up of up to 2 years. Peripheral blood leukocytes from 40 solid organ transplant ...
Tópico(s): Neonatal Health and Biochemistry
2005 - Elsevier BV | Microbes and Infection
Sara Pignatelli, Paola Dal Monte, Giada Rossini, Maria Paola Landini,
Abstract Human cytomegalovirus (HCMV) clinical isolates display genetic polymorphisms in multiple genes. Some authors have suggested that those polymorphisms may be implicated in HCMV‐induced immunopathogenesis, as well as in strain‐specific behaviours, such as tissue‐tropism and ability to establish persistent or latent infections. This review summarises the features of the main clustered HCMV polymorphic open reading frames and also briefly cites other variable loci within the viral genome. The ...
Tópico(s): Toxoplasma gondii Research Studies
2004 - Wiley | Reviews in Medical Virology
Paola Dal Monte, Sara Pignatelli, Giada Rossini, Maria Paola Landini,
Human cytomegalovirus (HCMV) clinical isolates display genetic polymorphisms, which are supposed to be implicated in strain-specific tissue tropism and HCMV-induced immunopathogenesis. One highly variable gene is ORF UL73, encoding for the envelope glycoprotein gN, which displays both a structural and an immunologic role as a component of the high-molecular weight complex gC-II. UL73 showed clustered polymorphisms, which originate four distinct genomic variants, denoted gN-1, gN-2, gN-3, and gN-4. ...
Tópico(s): Toxoplasma gondii Research Studies
2004 - Elsevier BV | Human Immunology
Barbara Pavan, Sara Fiorini, Massimo Dal Monte, Laura Lunghi, Carla Biondi, Paola Bagnoli, Davide Cervia,
Tópico(s): Neuroendocrine Tumor Research Advances
2004 - Springer Science+Business Media | Naunyn-Schmiedeberg s Archives of Pharmacology
Gabriela Pérez-Barrón, José Guillermo Ávila-Acevedo, Ana María García‐Bores, Sergio Montes, Sara García‐Jiménez, Ismael León‐Rivera, Moisés Rubio‐Osornio, Antonio Monroy‐Noyola,
Tópico(s): Cholinesterase and Neurodegenerative Diseases
2014 - Springer Science+Business Media | Journal of Natural Medicines
Alberto Monroy, Miguel A. Gómez‐Lim, Benny Weiss‐Steider, Jorge Hernández‐Montes, Sara Huerta‐Yépez, Jesus Rangel-Santiago, Edelmiro Santiago‐Osorio, Marı́a de Lourdes Mora-Garcı́a,
Tópico(s): Plant Virus Research Studies
2013 - Springer Science+Business Media | Archives of Virology
Pankaj Arora, Connie Wu, Abigail Khan, Donald B. Bloch, Brandi N. Davis‐Dusenbery, Anahita Ghorbani, Ester Spagnolli, Andrew Martinez, Allicia Ryan, Laurel T. Tainsh, Samuel M. Kim, Jian Rong, Tianxiao Huan, Jane E. Freedman, Daniel Levy, Karen K. Miller, Akiko Hata, Federica del Monte, Sara Vandenwijngaert, Melissa Swinnen, Stefan Janssens, Tara M. Holmes, Emmanuel S. Buys, Kenneth D. Bloch, Christopher Newton‐Cheh, Thomas J. Wang,
Numerous common genetic variants have been linked to blood pressure, but no underlying mechanism has been elucidated. Population studies have revealed that the variant rs5068 (A/G) in the 3′ untranslated region of NPPA, the gene encoding atrial natriuretic peptide (ANP), is associated with blood pressure. We selected individuals on the basis of rs5068 genotype (AG vs. AA) and fed them a low- or high-salt diet for 1 week, after which they were challenged with an intravenous saline infusion. On both ...
Tópico(s): Circular RNAs in diseases
2013 - American Society for Clinical Investigation | Journal of Clinical Investigation
Sara Pignatelli, Paola Dal Monte, Maria Paola Landini,
Clinical isolates of human cytomegalovirus (HCMV) show differences in tissue tropism, severity of clinical manifestations and ability to establish persistent or latent infections, characteristics that are thought to be related to genomic variation among strains. This work analysed the genomic variants of a new HCMV polymorphic locus, open reading frame (ORF) UL73. This ORF encodes the envelope glycoprotein gpUL73 (gN), which associates in a high molecular mass complex with its counterpart, gM, and ...
Tópico(s): HIV Research and Treatment
2001 - Microbiology Society | Journal of General Virology
Sara Rezzola, Massimo Dal Monte, Mirella Belleri, Antonella Bugatti, Paola Chiodelli, Michela Corsini, Maurizio Cammalleri, Anna Cancarini, Lucia Morbidelli, Pasqua Oreste, Paola Bagnoli, Francesco Semeraro, Marco Presta,
Vascular endothelial growth factor (VEGF) blockers have been developed for the treatment of proliferative diabetic retinopathy (PDR), the leading cause of visual impairments in the working-age population in the Western world. However, limitations to anti-VEGF therapies may exist because of the local production of other proangiogenic factors that may cause resistance to anti-VEGF interventions. Thus, novel therapeutic approaches targeting additional pathways are required. Here, we identified a sulfated ...
Tópico(s): Glaucoma and retinal disorders
2015 - American Diabetes Association | Diabetes