Carolina Henríquez, Andrés Córdova, Sergio Almonacid, Jorge Saavedra,
The apple peel, a by-product of apple processing, has a high total phenolic content (TPC); however, these compounds can be highly thermosensitive and unstable. Therefore, the aim of this study was to determine the degradation kinetics of the TPC in apple peels during drum-drying as a stabilization and recovery method. Apple peels (Granny Smith) were dried at 110, 120, 130 or 140 °C for 250 s with a constant drum clearance (0.2 mm). TPC degradation exhibited first-order kinetics and their retentions ...
Tópico(s): Microencapsulation and Drying Processes
2014 - Elsevier BV | Journal of Food Engineering
Noé Medina-Córdova, Sergio Rosales‐Mendoza, Luis Guillermo Hernández-Montiel, Carlos Angulo,
The yeast Debaryomyces hansenii has proven high efficiency against several pathogenic fungi in a variety of niches. Several terrestrial and marine D. hansenii strains have been tested for their prospective use in biological control of fungal contamination in foods. Herein, the potential application of D. hansenii in the biological control of fungal pathogens in fruits, dairy products, processed meats, and cereals are reviewed and placed in perspective; including the involved mechanisms of action. ...
Tópico(s): Identification and Quantification in Food
2018 - Elsevier BV | Biological Control
Produção Nacional
Pedro Toledo, Hamilton Klimach, David Cordova, Sérgio Bampi, Eric Fabris,
In this paper a self-biased current reference based on Metal-Oxide-Semiconductor Field Effect Transistor (MOSFET) Zero Temperature Coefficient (ZTC) condition is proposed. It can be implemented in any Complementary Metal-Oxide-Semiconductor (CMOS) fabrication process and provides another alternative to design current references. In order to support the circuit design, ZTC condition is analyzed using a MOSFET model that is continuous from weak to strong inversion, showing that this condition always ...
Tópico(s): Semiconductor materials and devices
2020 - | Journal of Integrated Circuits and Systems
Enrique Otero, Sergio Córdova, Fabian Diaz, Imelda Garcia‐Teruel, Óscar H. Del Brutto,
Summary: A healthy 7‐year‐old boy developed a language disorder associated with clinical seizures and a paroxysmal EEC Computed tomography and magnetic resonance imaging revealed a small cysticercus deep in the left Sylvian fissure. We postulate a cause and effect relationship between the parasitic cyst and the clinical manifestations supported by the strategic location of the cyst and the critical age at which this lesion developed. This case provides evidence that the syndrome of acquired epileptic ...
Tópico(s): Epilepsy research and treatment
1989 - Wiley | Epilepsia
P Loiseau, B Duché, Sergio Córdova, Jean‐François Dartigues, S Cohadon,
Summary: A spontaneous and complete recovery of benign childhood epilepsy with centrotemporal or rolandic spikes (BECT) is taken for granted. However, some authors have reported the occurrence of generalized tonic‐clonic seizures in a few adult patients and in some children who have seizures after a long period without problems. The aims of this study were (a).to search for early predictors of outcome and (b) to ascertain the long‐term prognosis of BECT in a large group of patients. An attempt to relocate ...
Tópico(s): Pharmacological Effects and Toxicity Studies
1988 - Wiley | Epilepsia
Marco T. Medina, Pierre Genton, María C. Montoya, Sergio Córdova, Charlotte Dravet, Julio Sotelo,
Summary: Epilepsy secondary to active or inactive neurocysticercosis (NCC) is a major public health problem in Latin American countries. In an open‐label pilot trial, we evaluated and followed (mean = 13 months) 16 patients with epilepsy resulting from active NCC which was treated with anticisticercal (ACC) drugs. These patients were aged 12–68 years with confirmed active NCC and seizures not controlled by adequate antiepileptic drug (AED) therapy. Patients were treated with albendazole or praziquantel ( ...
Tópico(s): Parasite Biology and Host Interactions
1993 - Wiley | Epilepsia
A. W. Liu, Antonio V. Delgado‐Escueta, Manyee Gee, José M. Serratosa, Q. W. Zhang, Ma. Elisa Alonso, Marco T. Medina, Sergio Córdova, Hongyu Zhao, J. M. Spellman, F Rubio Donnadieu, Jaime Ramos Peek, Lucy J. Treiman, R S Sparkes,
We recently analyzed under homogeneity a large pedigree from Belize with classic juvenile myoclonic epilepsy (JME). After a genome wide search with 146 microsatellites, we obtained significant linkage between chromosome 6p markers, D6S257 and D6S272, and both convulsive and EEG traits of JME. Recombinations in two affected members defined a 40 cM JME region flanked by D6S313 and D6S258. In the present communication, we explored if the same chromosome 6p11 microsatellites also have a role in JME mixed ...
Tópico(s): Glycogen Storage Diseases and Myoclonus
1996 - Wiley | American Journal of Medical Genetics
Toshimitsu Suzuki, Antonio V. Delgado‐Escueta, Kripamoy Aguan, María Elisa Alonso, Shi Jun, Yuji Hara, Motohiro Nishida, Tomohiro Numata, Marco T. Medina, Tamaki Takeuchi, Ryoji Morita, Dongsheng Bai, Subramaniam Ganesh, Yoshihisa Sugimoto, Johji Inazawa, Julia N. Bailey, Adriana Ochoa, Aurelio Jara‐Prado, Astrid Rasmussen, Jaime Ramos‐Peek, Sergio Córdova, Francisco Rubio‐Donnadieu, Yushi Inoue, Makiko Ōsawa, Sunao Kaneko, Hirokazu Oguni, Yasuo Mori, Kazuhiro Yamakawa,
Tópico(s): Epilepsy research and treatment
2004 - Nature Portfolio | Nature Genetics
Armando Delgado, Sergio Cordova, Israel Lopez, David C. Nemir, Evgeny Shafirovich,
Magnesium silicide (Mg2Si) is a promising intermetallic compound for applications such as light-weight composite materials and thermoelectric energy conversion. It is difficult, however, to synthesize high-quality Mg2Si on a large scale. Self-propagating high-temperature synthesis (SHS) is an attractive pathway, but it is difficult to ignite the low-exothermic Mg/Si mixture and achieve a self-sustained propagation of the combustion wave. In the present paper, mechanical activation was used to facilitate ...
Tópico(s): Thermal and Kinetic Analysis
2015 - Elsevier BV | Journal of Alloys and Compounds
Armando Delgado, Sergio Cordova, Evgeny Shafirovich,
It has been shown recently that mixtures of JSC-1A lunar regolith simulant with magnesium are combustible. Thermite-type reactions in these mixtures could be used for in situ production of construction materials on the Moon. Because of complex composition of lunar regolith, however, the mechanisms of these reactions are not well understood. Also, for Mars mission applications, it is important to explore the possibility of using Martian regolith in such mixtures. In the present paper, combustion ...
Tópico(s): Combustion and Detonation Processes
2015 - Elsevier BV | Combustion and Flame
Sergio Córdova-Rivas, Ixamail Fraire-Soto, Andrea Mercado-Casas Torres, Luis Steven Servín-González, Angélica Judith Granados‐López, Yamilé López‐Hernández, Claudia Araceli Reyes Estrada, Rosalinda Gutiérrez-Hernández, Julio Enrique Castañeda‐Delgado, Leticia A Ramirez-Hernandez, José A. Varela-Silva, Jesús Adrián López,
The micro RNA (miR)-34 family is composed of 5p and 3p strands of miR-34a, miR-34b, and miR-34c. The 5p strand’s expression and function is studied in cervical cancer. The 3p strand’s function and regulation remain to be elucidated. To study the function of the passenger strands of miR-34 family members, we overexpressed 5p and 3p strands using a synthetic miRNA in cervical cell lines. Cell proliferation was evaluated using crystal violet. Migration and invasion were tested using transwell assays, ...
Tópico(s): Cancer-related molecular mechanisms research
2019 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Sergio Cordova, Kevin Estala-Rodriguez, Evgeny Shafirovich,
Knowledge of the oxidation kinetics of magnesium (Mg) particles is important for the development of advanced propulsion and power systems based on combustion of metals. However, reports on the high-temperature oxidation of Mg powders in oxygen are contradictory. In the present work, the oxidation of spherical and non-spherical (flakes) Mg particles in O2 flow was investigated using isothermal and non-isothermal thermogravimetry. Three fractions of the spherical powder were tested, with average sizes ...
Tópico(s): Chemical Thermodynamics and Molecular Structure
2021 - Elsevier BV | Combustion and Flame
Md Sahid Hassan, Kazi Md Masum Billah, Samuel Ernesto Hall, Sergio Sepulveda, Jaime E. Regis, Cory Marquez, Sergio Cordova, Jasmine Whitaker, Thomas W. Robison, James Keating, Evgeny Shafirovich, Yirong Lin,
Thermoplastic materials such as PA12 and PA6 have been extensively employed in Selective Laser Sintering (SLS) 3D printing applications due to their printability, processability, and crystalline structure. However, thermoplastic-based materials lack polymer inter-chain bonding, resulting in inferior mechanical and thermal properties and relatively low fatigue behavior. Therefore, 3D printing of high-performance crosslinked thermosets using SLS technology is paramount to pursue as an alternative to ...
Tópico(s): Injection Molding Process and Properties
2022 - Multidisciplinary Digital Publishing Institute | Journal of Composites Science
Dongsheng Bai, María Elisa Alonso, Marco T. Medina, Julia N. Bailey, Ryoji Morita, Sergio Córdova, Astrid Rasmussen, Jaime Ramos‐Peek, Adriana Ochoa, Aurelio Jara‐Prado, F Rubio Donnadieu, Gilbert Cadena, Kazuhiro Yamakawa, Antonio V. Delgado‐Escueta,
Juvenile myoclonic epilepsy is a common subtype of idiopathic epilepsy accounting for 4-11% of all epilepsies. We reported previously significant evidence of linkage between chromosome 6p12-11 microsatellites and the clinical epilepsy and EEG traits of JME families from Belize and Los Angeles. To narrow the JME region, we ascertained and genotyped 31 new JME families from Mexico using a later generation of Généthon microsatellites. Two point linkage analyses obtained significant Z(max) values of ...
Tópico(s): Sleep and Wakefulness Research
2002 - Wiley | American Journal of Medical Genetics
Antonio V. Delgado‐Escueta, Katerina B. Perez‐Gosiengfiao, Dongsheng Bai, Julia N. Bailey, Marco T. Medina, Ryoji Morita, Toshimitsu Suzuki, Subramaniam Ganesh, Toshihisa Sugimoto, Kazuhiro Yamakawa, Adriana Ochoa, Aurelio Jara‐Prado, Astrid Rasmussen, Jaime Ramos‐Peek, Sergio Córdova, Francisco Rubio‐Donnadieu, María Elisa Alonso,
Summary: Understanding the latest advances in the molecular genetics of the epilepsies is important, as it provides a basis for comprehending the new practice of epileptology. Epilepsies have traditionally been classified and subtyped on the basis of clinical and neurophysiologic concepts. However, the complexity and variability of phenotypes and overlapping clinical features limit the resolution of phenotype‐based classification and confound epilepsy nosology. Identification of tightly linked epilepsy ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2003 - Wiley | Epilepsia
Toshimitsu Suzuki, Ryoji Morita, Yoshihisa Sugimoto, Takashi Sugawara, Dongsheng Bai, María Elisa Alonso, Marco T. Medina, Julia N. Bailey, Astrid Rasmussen, Jaime Ramos‐Peek, Sergio Córdova, Francisco Rubio‐Donnadieu, Adriana Ochoa, Aurelio Jara‐Prado, Johji Inazawa, Antonio V. Delgado‐Escueta, Kazuhiro Yamakawa,
Juvenile myoclonic epilepsy (JME) is one of the most frequent hereditary epilepsies characterized by myoclonic and tonic-clonic convulsions beginning at 8-20 years of age. Genetic studies have revealed four major chromosomal loci on 6p21.3, 6p11-12, 6q24, and 15q14 as candidate regions harboring genes responsible for JME. Previously we reported the region on 6p11-p12 (EJM1), and here we report the identification and mutational analysis of candidate genes for EJM1. One of those is a leucine-rich repeat- ...
Tópico(s): Epilepsy research and treatment
2002 - Elsevier BV | Epilepsy Research
... Administration under grant no. 80NSSC20K0293. The author thanks Sergio Cordova (currently at Northrop Grumman) and Steven L. Rickman ... Administration under grant no. 80NSSC20K0293. The author thanks Sergio Cordova (currently at Northrop Grumman) and Steven L. Rickman ...
Tópico(s): Energetic Materials and Combustion
2023 - American Institute of Aeronautics and Astronautics | Journal of Propulsion and Power
Produção Nacional
Revisado por pares
Christian M. Ibáñez, Mariana Díaz‐Santana‐Iturrios, David A. López‐Córdova, Sergio A. Carrasco, M. Cecilia Pardo‐Gandarillas, Francisco Rocha, Érica Alves González Vidal,
A central question in the evolution of life-histories is whether organisms reproduce once or repeatedly. For cephalopods, the main differences between semelparous and iteroparous are based on ovulation pattern and spawning type. The different reproductive strategies in coleoid cephalopods could be related to the habitat in which the species dwell (coastal vs. oceanic) and/or to environmental forces, thus, both aspects should be quantitatively evaluated under an evolutionary perspective to reconstruct: ( ...
Tópico(s): Crustacean biology and ecology
2020 - Elsevier BV | Molecular Phylogenetics and Evolution
Sergio Córdova-Rivas, Jorge Gustavo Araujo-Huitrado, Ernesto Rivera-Ávalos, Ismailía L. Escalante-García, S.M. Durón-Torres, Yamilé López‐Hernández, Hiram Hernández‐López, Lluvia Itzel López-López, Denisse de Loera, Jesús Adrián López,
We previously showed that microwave assisted synthesis is the best method for the synthesis of naphthoquinone amino acid and chloride-naphthoquinone amino acid derivatives by a complete evaluation of reaction conditions such as stoichiometry, bases, and pH influence. Following the same strategy, we synthesized chloride and non-chloride tyrosine, valine, and tryptophan-naphthoquinones achieving 85–95%, 80–92%, and 91–95% yields, respectively. The cyclic voltammetry profiles showed that both series ...
Tópico(s): Free Radicals and Antioxidants
2020 - Multidisciplinary Digital Publishing Institute | Molecules
Toshimitsu Suzuki, Antonio V. Delgado‐Escueta, María Elisa Alonso, Ryoji Morita, Nami Okamura, Yoshihisa Sugimoto, Dongsheng Bai, Marco T. Medina, Julia N. Bailey, Astrid Rasmussen, Jaime Ramos‐Peek, Sergio Córdova, Francisco Rubio‐Donnadieu, Adriana Ochoa, Aurelio Jara‐Prado, Johji Inazawa, Kazuhiro Yamakawa,
Juvenile myoclonic epilepsy (JME) is a distinct form of idiopathic generalized epilepsy (IGE). One of the candidate regions for human JME has been mapped on chromosome band 6p11-p12 by linkage analyses and is termed EJM1 (MIM 254770). Recently, we reported the reduction of the EJM1 region to 3.5cM that contains 18 genes, the exclusion of three genes (LRRC1, GCLC, KIAA0057) by mutation analyses, and the identification of Myoclonin1/EFHC1 as the EJM1 gene. Here, we describe detailed physical and transcriptome ...
Tópico(s): Amino Acid Enzymes and Metabolism
2006 - Elsevier BV | Neuroscience Letters
Produção Nacional
Revisado por pares
Arthur Campos de Oliveira, David Cordova, Hamilton Klimach, Sérgio Bampi,
In this paper, a self-biased temperature compensated CMOS voltage reference operating at picowatt-level power consumption is presented. The core of the proposed circuit is the self-cascode MOSFET (SCM) and two variants are explored: a self-biased SCM (SBSCM) and a self-biased NMOS (SBNMOS) voltage reference. Power consumption and silicon area are remarkably reduced by combining subthreshold operation with a self-biased scheme. Trimming techniques for both circuits are discussed aiming at the reduction ...
Tópico(s): Semiconductor materials and devices
2017 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Circuits and Systems I Regular Papers
Produção Nacional
Revisado por pares
Arthur Campos de Oliveira, David Cordova, Hamilton Klimach, Sérgio Bampi,
In this paper, we propose an ultra-low power compact 3-transistor voltage reference capable of operating at ultra-low supply voltages. The proposed circuit is based on the self-cascode MOSFET (SCM), which provides a reference voltage proportional to the threshold voltage (VT) difference of the two NMOS transistors that compose it. Reverse short-channel and narrow-width effects are explored to obtain such VT difference while using the same type of transistor. Ultra-low power operation and low line ...
Tópico(s): Low-power high-performance VLSI design
2018 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Circuits and Systems I Regular Papers
Produção Nacional
Revisado por pares
Pedro Toledo, David Cordova, Hamilton Klimach, Sérgio Bampi, Paolo Crovetti,
A voltage reference based on MOSFETs operated under Zero Temperature Coefficient (ZTC) bias is proposed. The circuit operates in a power supply voltage range from 0.3 V up to 1.2 V and outputs three different reference voltages using Standard-VT (SVT), Low-VT (LVT), and Zero-VT (ZVT) MOS transistors biased near their ZTC point by a single PTAT current reference. Measurements on 15 circuit samples fabricated in a standard 0.13-μm CMOS process show a worst-case normalized standard deviation (σ/μ) of 3% ( ...
Tópico(s): Radio Frequency Integrated Circuit Design
2019 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Circuits & Systems II Express Briefs
Sergio Mauricio Castañeda Tovar, Ninosca Sofía Caiaffa Bermúdez,
El rendimiento físico y la composición corporal son elementos clave en la desarrollo de la labor operacional del Militar del Ejército de Colombia. El objetivo de este estudio fue establecer la relación entre la composición corporal y el rendimiento físico en los estudiantes de la Escuela Militar de Cadetes General José María Córdova. Se realizó un estudio descriptivo–correlacional donde se valoraron 51 estudiantes del género masculino (cabe aclarar que todos firmaron los consentimientos informados), ...
Tópico(s): Educational methodologies and cognitive development
2015 - | Revista Científica General José María Córdova
Produção Nacional
Revisado por pares
María Margarita Olivares, Ricardo Zwiener, Lina Maria Leiva Panqueva, Francisco Alberto Contreras Verduzco, Eli Mansour, Jairo Antonio Rodríguez, Solange Oliveira Rodrigues Valle, Sandra Nieto‐Martinez, Jane da Silva, Daniel Vázquez, Oscar Calderón Llosa, Fernanda Marcelino, Manuel Ratti Sisa, Ileana María Madrigal Beas, Rafael Zaragoza Urdaz, Eliana Toledo, Natalia Lorena Fili, Olga M. Barrera, Juan Carlos Fernandez de Cordova Aguirre, Sergio Castro Mora, Mauricio Sarrazola, Rodolfo Jaller Raad, Edison Morales Cardenas, Darío Josviack, Claudio Fantini, Monica Marocco, Elma Nievas, Faradiba Sarquis Serpa, Herberto José Chong‐Neto, Maria Luiza Oliva Alonso, Sérgio Duarte Dortas, Raisa G. Ulaf, Nelson Augusto Rosário Filho, Rodolfo Ramón Leyva Barrero, Anete Sevciovic Grumach,
Clinical ImplicationsWe observed that acute respiratory syndrome coronavirus 2 infection can trigger attacks in hereditary angioedema with or without C1 inhibitor deficiency; however, COVID-19 is not more severe than in non–hereditary angioedema patients. Previous use of androgens did not influence any of these aspects. We observed that acute respiratory syndrome coronavirus 2 infection can trigger attacks in hereditary angioedema with or without C1 inhibitor deficiency; however, COVID-19 is not ...
Tópico(s): Urticaria and Related Conditions
2021 - Elsevier BV | The Journal of Allergy and Clinical Immunology In Practice
A 41-year-old woman presented unconscious with fixed dilated pupils following a massive overdose of carbamazepine and an unknown quantity of venlafaxine prescribed for the management of bipolar affective disorder. Her course in the intensive care unit was marked by a number of complications related to the overdose including prolonged coma, seizures and cardiac arrest. The patient eventually recovered to leave hospital.
Tópico(s): Electrolyte and hormonal disorders
2000 - SAGE Publishing | Anaesthesia and Intensive Care
Antonio Canepa, Jennifer E. Purcell, Pablo Antonio Abrigo Còrdova, Miguel Fernández, Sergio Palma,
Blooms of stinging pelagic cnidarians have been causing increasing health problems for humans worldwide. Physalia physalis is among the worst stinging species in the Atlantic and Pacific oceans along the North and South American coasts. This siphonophore species has a large gas float and lives at the ocean surface, where its distribution is affected mainly by winds. P. physalis's strandings were observed in the southeastern Pacific Ocean for three consecutive years (2014 to 2016). Data of stranded ...
Tópico(s): Marine and environmental studies
2020 - Escuela de Ciencias del Mar, Facultad de Recursos Naturales, Pontificia Universidad Católica de Valparaíso | Latin American Journal of Aquatic Research
Sergio Mauricio Castañeda Tovar,
El objetivo de este estudio es establecer los indicadores técnicos y de rendimiento en natación en los 100 m libre para los cadetes y alféreces de la Escuela Militar. Se valoraron 300 cadetes del género masculino que realizan el proceso de formación como oficiales del Ejército Nacional en la Escuela Militar de Cadetes “General José María Córdova” en Bogotá. Las características de la población indican que la edad promedio es de 21,6 ± 2,8 años; la talla se ubicó en 1,73 ± 5,6 cm; los valores para el peso ...
Tópico(s): Educational methodologies and cognitive development
2014 - | Revista Científica General José María Córdova
Sergio Cordova, Evgeny Shafirovich,
Tópico(s): Advanced ceramic materials synthesis
2018 - Springer Science+Business Media | Journal of Materials Science
Francisco Córdova‐Zavaleta, Jaime Mendo, Sergio A. Briones‐Hernández, Nicolas Acuña‐Perales, Adriana González‐Pestana, Joanna Alfaro‐Shigueto, Jeffrey C. Mangel,
Tópico(s): Ichthyology and Marine Biology
2018 - National Oceanic and Atmospheric Administration | Fishery Bulletin