Yi Quan, Bin Zhou, Yanyun Wang, Ruiqi Duan, Kana Wang, Qianqian Gao, Shaoqing Shi, Yaping Song, Lin Zhang, Mingrong Xi,
Interleukin-17 (IL-17) is a proinflammatory cytokine that is associated with inflammation, autoimmune disorders, and even tumors. Previous studies revealed that a large group of human malignant tumors have abnormally high IL-17 expression. In the present study, we analyzed two single-nucleotide polymorphisms (SNPs) in the IL17A (rs2275913) and IL17F (rs763780) in 311 cervical cancer patients and 463 controls using TaqMan assays. Our results indicated that the frequencies of AA genotype and A allele ...
Tópico(s): Cervical Cancer and HPV Research
2012 - Hindawi Publishing Corporation | Clinical and Developmental Immunology
Vipin Gopinath, Sajith Raghunandanan, Roshna Lawrence Gomez, Leny Jose, Arun Surendran, Ranjit Ramachandran, Akhil Raj Pushparajan, Sathish Mundayoor, Abdul Jaleel, Ramakrishnan Ajay Kumar,
... 11945-11950Crossref PubMed Scopus (383) Google Scholar, 11.Shi L. Sohaskey C. Kana B. Dawes S. North R. Changes in energy ...
Tópico(s): Gut microbiota and health
2015 - Elsevier BV | Molecular & Cellular Proteomics
Koki Hoshi, Yoshinobu Kariya, Kiyomitsu Nara, Hiromi Ito, K. Matsumoto, Masamichi Nagae, Yoshiki Yamaguchi, Madoka Nakajima, M. Miyajima, Hiroyuki Arai, Atsushi Kuno, Hisashi Narimatsu, Keiro Shirotani, Yasuhiro Hashimoto,
... on: Oxford Academic PubMed Google Scholar Kana Matsumoto, Kana Matsumoto 1Department of Biochemistry, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima-shi, Fukushima 960-1295; 2Structural Glycobiology Team, Systems Glycobiology ...
Tópico(s): Galectins and Cancer Biology
2013 - Oxford University Press | The Journal of Biochemistry
... Isma'il, ‘Min al-Najaf ila Shaqra’ tariq shi'r wa thaqafa wa din: kayfa kana al-intiqal wa al-‘awda min al-hawza ...
Tópico(s): Jewish and Middle Eastern Studies
2009 - Routledge | British Journal of Middle Eastern Studies
Lanbo Shi, Charles D. Sohaskey, Bavesh D Kana, Stephanie S. Dawes, R J North, Valerie Mizrahi, Maria Laura Gennaro,
Transcription profiling of genes encoding components of the respiratory chain and the ATP synthesizing apparatus of Mycobacterium tuberculosis was conducted in vivo in the infected mouse lung, and in vitro in bacterial cultures subjected to gradual oxygen depletion and to nitric oxide treatment. Transcript levels changed dramatically as infection progressed from bacterial exponential multiplication (acute infection) to cessation of bacterial growth (chronic infection) in response to host immunity. ...
Tópico(s): Pneumonia and Respiratory Infections
2005 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Juha P. Väyrynen, Koichiro Haruki, Mai Chan Lau, Sara A. Väyrynen, Tomotaka Ugai, Naohiko Akimoto, Rong Zhong, Melissa Zhao, Andressa Dias Costa, Jennifer Borowsky, Phoenix Bell, Yasutoshi Takashima, Kenji Fujiyoshi, Kota Arima, Junko Kishikawa, Shanshan Shi, Tyler S. Twombly, Mingyang Song, Kana Wu, Andrew T. Chan, Xuehong Zhang, Charles S. Fuchs, Jeffrey A. Meyerhardt, Marios Giannakis, Shuji Ogino, Jonathan A. Nowak,
Abstract Although tumor-infiltrating T cells hold a beneficial prognostic role in colorectal cancer, other lymphocytic populations are less characterized. We developed a multiplexed immunofluorescence assay coupled with digital image analysis and machine learning to identify natural killer (NK) cells (NCAM1+CD3−), natural killer T-like (NKT-like) cells (NCAM1+CD3+), and T cells (NCAM1−CD3+) within the PTPRC+ (CD45+) cell population and to measure their granzyme B (GZMB; cytotoxicity marker) and FCGR3A ( ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2021 - American Association for Cancer Research | Cancer Immunology Research
Raaj S. Mehta, Mingyang Song, Reiko Nishihara, David A. Drew, Kana Wu, Zhi Rong Qian, Teresa T. Fung, Tsuyoshi Hamada, Yohei Masugi, Annacarolina da Silva, Yan Shi, Wanwan Li, Mancang Gu, Walter C. Willett, Charles S. Fuchs, Edward L. Giovannucci, Shuji Ogino, Andrew T. Chan,
Background & AimsWestern and prudent dietary patterns have been associated with higher and lower risks of colorectal cancer (CRC), respectively. However, little is known about the associations between dietary patterns and specific anatomic subsites or molecular subtypes of CRC.MethodsWe used multivariable Cox proportional hazards models to examine the associations between Western and prudent dietary patterns and CRC risk in the Health Professionals Follow-up Study and Nurses’ Health Study.ResultsAfter ...
Tópico(s): Genetic factors in colorectal cancer
2017 - Elsevier BV | Gastroenterology
Bin Zhou, Peng Bai, Hui Xue, Zhu Zhang, Shaoqing Shi, Kui Zhang, Yanyun Wang, Kana Wang, Yi Quan, Yaping Song, Lin Zhang,
Tópico(s): Molecular Biology Techniques and Applications
2014 - Springer Science+Business Media | Familial Cancer
Siti Muharami Malayu, Yuddi Adrian Muliadi, Lisa Mayasari,
... appear are unfinished sentences, anou, iisashi hyougen, -tari, -shi, -kana, -toka and appear in the implicatures of explaining, ...
Tópico(s): Language Acquisition and Education
2023 - | MIGRATION LETTERS
Tsuyoshi Hamada, Li Liu, Jonathan A. Nowak, Kosuke Mima, Yin Cao, Kimmie Ng, Tyler S. Twombly, Mingyang Song, Seungyoun Jung, Ruoxu Dou, Yohei Masugi, Keisuke Kosumi, Yan Shi, Annacarolina da Silva, Mancang Gu, Wanwan Li, NaNa Keum, Kana Wu, Katsuhiko Nosho, Kentaro Inamura, Jeffrey A. Meyerhardt, Daniel Nevo, Molin Wang, Marios Giannakis, Andrew T. Chan, Edward L. Giovannucci, Charles S. Fuchs, Reiko Nishihara, Xuehong Zhang, Shuji Ogino,
High-level plasma 25-hydroxyvitamin D [25(OH)D] has been associated with lower colorectal cancer incidence and mortality. Considering evidence indicating immunomodulatory effects of vitamin D, we hypothesised that survival benefits from high systemic vitamin D level might be stronger for colorectal carcinoma with lower immune response to tumour.Using 869 colon and rectal cancer cases within the Nurses' Health Study and Health Professionals Follow-up Study, we assessed the prognostic association of ...
Tópico(s): Cancer Immunotherapy and Biomarkers
2018 - Elsevier BV | European Journal of Cancer
Kota Arima, Rong Zhong, Tomotaka Ugai, Melissa Zhao, Koichiro Haruki, Naohiko Akimoto, Mai Chan Lau, Kazuo Okadome, Raaj S. Mehta, Juha P. Väyrynen, Junko Kishikawa, Tyler S. Twombly, Shanshan Shi, Kenji Fujiyoshi, Keisuke Kosumi, Yoko Ogata, Hideo Baba, Fenglei Wang, Kana Wu, Mingyang Song, Xuehong Zhang, Charles S. Fuchs, Cynthia L. Sears, Walter C. Willett, Edward L. Giovannucci, Jeffrey A. Meyerhardt, Wendy S. Garrett, Curtis Huttenhower, Andrew T. Chan, Jonathan A. Nowak, Marios Giannakis, Shuji Ogino,
Background & AimsEvidence supports a carcinogenic role of Escherichia coli carrying the pks island that encodes enzymes for colibactin biosynthesis. We hypothesized that the association of the Western-style diet (rich in red and processed meat) with colorectal cancer incidence might be stronger for tumors containing higher amounts of pks+ E coli.MethodsWestern diet score was calculated using food frequency questionnaire data obtained every 4 years during follow-up of 134,775 participants in 2 United ...
Tópico(s): Gut microbiota and health
2022 - Elsevier BV | Gastroenterology
Juha P. Väyrynen, Mai Chan Lau, Koichiro Haruki, Sara A. Väyrynen, Andressa Dias Costa, Jennifer Borowsky, Melissa Zhao, Kenji Fujiyoshi, Kota Arima, Tyler S. Twombly, Junko Kishikawa, Simeng Gu, Saina Aminmozaffari, Shanshan Shi, Yoshifumi Baba, Naohiko Akimoto, Tomotaka Ugai, Annacarolina da Silva, Mingyang Song, Kana Wu, Andrew T. Chan, Reiko Nishihara, Charles S. Fuchs, Jeffrey A. Meyerhardt, Marios Giannakis, Shuji Ogino, Jonathan A. Nowak,
Abstract Purpose: Although high T-cell density is a well-established favorable prognostic factor in colorectal cancer, the prognostic significance of tumor-associated plasma cells, neutrophils, and eosinophils is less well-defined. Experimental Design: We computationally processed digital images of hematoxylin and eosin (H&E)–stained sections to identify lymphocytes, plasma cells, neutrophils, and eosinophils in tumor intraepithelial and stromal areas of 934 colorectal cancers in two prospective ...
Tópico(s): Inflammatory Biomarkers in Disease Prognosis
2020 - American Association for Cancer Research | Clinical Cancer Research
Produção Nacional
Revisado por pares
Tsuyoshi Hamada, Yin Cao, Zhi Rong Qian, Yohei Masugi, Jonathan A. Nowak, Juhong Yang, Mingyang Song, Kosuke Mima, Keisuke Kosumi, Li Liu, Yan Shi, Annacarolina da Silva, Mancang Gu, Wanwan Li, NaNa Keum, Xuehong Zhang, Kana Wu, Jeffrey A. Meyerhardt, Edward L. Giovannucci, Marios Giannakis, Scott J. Rodig, Gordon J. Freeman, Daniel Nevo, Molin Wang, Andrew T. Chan, Charles S. Fuchs, Reiko Nishihara, Shuji Ogino,
Purpose Blockade of the programmed cell death 1 (PDCD1, PD-1) immune checkpoint pathway can improve clinical outcomes in various malignancies. Evidence suggests that aspirin (a widely used nonsteroidal anti-inflammatory drug) not only prolongs colorectal cancer survival, but can also activate T cell–mediated antitumor immunity and synergize with immunotherapy through inhibition of prostaglandin E2 production. We hypothesized that the survival benefit associated with aspirin might be stronger in colorectal ...
Tópico(s): Colorectal Cancer Treatments and Studies
2017 - Lippincott Williams & Wilkins | Journal of Clinical Oncology
Kosuke Mima, Jonathan A. Nowak, Zhi Rong Qian, Yin Cao, Mingyang Song, Yohei Masugi, Yan Shi, Annacarolina da Silva, Mancang Gu, Wanwan Li, Tsuyoshi Hamada, Xuehong Zhang, Kana Wu, Jeffrey A. Meyerhardt, Hideo Baba, Edward L. Giovannucci, Andrew T. Chan, Charles S. Fuchs, Shuji Ogino, Reiko Nishihara,
Colorectal tumors arise with genomic and epigenomic alterations through interactions between neoplastic cells, immune cells, and microbiota that vary along the proximal to distal axis of colorectum. Long interspersed nucleotide element-1 (LINE-1) hypomethylation in colorectal cancer has been associated with worse clinical outcome. Utilizing 1,317 colon and rectal carcinoma cases in two U.S.-nationwide prospective cohort studies, we examined patient survival according to LINE-1 methylation level stratified ...
Tópico(s): Tannin, Tannase and Anticancer Activities
2016 - Impact Journals LLC | Oncotarget
Tsuyoshi Hamada, Xuehong Zhang, Kosuke Mima, Susan Bullman, Yasutaka Sukawa, Jonathan A. Nowak, Keisuke Kosumi, Yohei Masugi, Tyler S. Twombly, Yin Cao, Mingyang Song, Li Liu, Annacarolina da Silva, Yan Shi, Mancang Gu, Wanwan Li, Hideo Koh, Katsuhiko Nosho, Kentaro Inamura, NaNa Keum, Kana Wu, Jeffrey A. Meyerhardt, Aleksandar D. Kostic, Curtis Huttenhower, Wendy S. Garrett, Matthew Meyerson, Edward L. Giovannucci, Andrew T. Chan, Charles S. Fuchs, Reiko Nishihara, Marios Giannakis, Shuji Ogino,
The presence of Fusobacterium nucleatum (F. nucleatum) in colorectal carcinoma tissue has been associated with microsatellite instability (MSI), lower-level T-cell infiltrates, and poor clinical outcomes. Considering differences in the tumor-immune microenvironment between MSI-high and non-MSI-high carcinomas, we hypothesized that the association of F. nucleatum with immune response might differ by tumor MSI status. Using samples from 1,041 rectal and colon cancer patients within the Nurses' Health ...
Tópico(s): Colorectal Cancer Screening and Detection
2018 - American Association for Cancer Research | Cancer Immunology Research
Juha P. Väyrynen, Koichiro Haruki, Mai Chan Lau, Sara A. Väyrynen, Rong Zhong, Andressa Dias Costa, Jennifer Borowsky, Melissa Zhao, Kenji Fujiyoshi, Kota Arima, Tyler S. Twombly, Junko Kishikawa, Simeng Gu, Saina Aminmozaffari, Shanshan Shi, Yoshifumi Baba, Naohiko Akimoto, Tomotaka Ugai, Annacarolina da Silva, Jennifer L. Guerriero, Mingyang Song, Kana Wu, Andrew T. Chan, Reiko Nishihara, Charles S. Fuchs, Jeffrey A. Meyerhardt, Marios Giannakis, Shuji Ogino, Jonathan A. Nowak,
Abstract Macrophages are among the most common cells in the colorectal cancer microenvironment, but their prognostic significance is incompletely understood. Using multiplexed immunofluorescence for CD68, CD86, IRF5, MAF, MRC1 (CD206), and KRT (cytokeratins) combined with digital image analysis and machine learning, we assessed the polarization spectrum of tumor-associated macrophages in 931 colorectal carcinomas. We then applied Cox proportional hazards regression to assess prognostic survival associations ...
Tópico(s): Adipokines, Inflammation, and Metabolic Diseases
2020 - American Association for Cancer Research | Cancer Immunology Research
Wei Shi, Kana Wu, Hui Li, Huafeng Zhang,
Tópico(s): Peripheral Nerve Disorders
2025 - E.U.E.P. European Publishing | Tobacco Induced Diseases
Zhonghua Shi, Zhi Li, Kana Wang, Fan Yang,
Observational studies have reported an association between gastroesophageal reflux disease (GERD) and endometriosis. We conducted a two-sample and bidirectional Mendelian randomization analysis to determine whether those associations are causal. Two-sample and bidirectional MR analyses were performed using summary statistics from the European Individual Genome-Wide Association Study (GWAS). The inverse variance weighting (IVW) method is used as the main analysis method to evaluate causality. Sensitivity ...
Tópico(s): Gynecological conditions and treatments
2024 - Frontiers Media | Frontiers in Medicine
Jin-Xing Shi, Kana Yoshizumi, Masatoshi SHIMODA, Shinobu SAKAI,
Tópico(s): Structural Analysis and Optimization
2021 - Springer Science+Business Media | Structural and Multidisciplinary Optimization
Juha P. Väyrynen, Koichiro Haruki, Sara A. Väyrynen, Mai Chan Lau, Andressa Dias Costa, Jennifer Borowsky, Melissa Zhao, Tomotaka Ugai, Junko Kishikawa, Naohiko Akimoto, Rong Zhong, Shanshan Shi, Tzuu-Wang Chang, Kenji Fujiyoshi, Kota Arima, Tyler S. Twombly, Annacarolina da Silva, Mingyang Song, Kana Wu, Xuehong Zhang, Andrew T. Chan, Reiko Nishihara, Charles S. Fuchs, Jeffrey A. Meyerhardt, Marios Giannakis, Shuji Ogino, Jonathan A. Nowak,
Background Myeloid cells represent an abundant yet heterogeneous cell population in the colorectal cancer microenvironment, and their roles remain poorly understood. Methods We used multiplexed immunofluorescence combined with digital image analysis to identify CD14 + monocytic and CD15 + granulocytic cells and to evaluate their maturity (HLA-DR and CD33), immunosuppressive potential (ARG1) and proximity to cytokeratin (KRT)-positive tumor cells in 913 colorectal carcinomas. Using covariate data of 4465 ...
Tópico(s): Immune Response and Inflammation
2021 - BMJ | Journal for ImmunoTherapy of Cancer
Keisuke Kosumi, Tsuyoshi Hamada, Hideo Koh, Jennifer Borowsky, Susan Bullman, Tyler S. Twombly, Daniel Nevo, Yohei Masugi, Li Liu, Annacarolina da Silva, Yang Chen, Chunxia Du, Mancang Gu, Chenxi Li, Wanwan Li, Hongli Liu, Yan Shi, Kosuke Mima, Mingyang Song, Katsuhiko Nosho, Jonathan A. Nowak, Reiko Nishihara, Hideo Baba, Xuehong Zhang, Kana Wu, Molin Wang, Curtis Huttenhower, Wendy S. Garrett, Matthew Meyerson, Jochen K. Lennerz, Marios Giannakis, Andrew T. Chan, Jeffrey A. Meyerhardt, Charles S. Fuchs, Shuji Ogino,
Evidence indicates a complex link between microbiota, tumor characteristics, and host immunity in the tumor microenvironment. In experimental studies, bifidobacteria appear to modulate intestinal epithelial cell differentiation. Accumulating evidence suggests that bifidobacteria may enhance the antitumor immunity and efficacy of immunotherapy. We hypothesized that the amount of bifidobacteria in colorectal carcinoma tissue might be associated with tumor differentiation and higher immune response ...
Tópico(s): Gut microbiota and health
2018 - Elsevier BV | American Journal Of Pathology
Hideo Koh, Tsuyoshi Hamada, Mingyang Song, Li Liu, Yin Cao, Jonathan A. Nowak, Annacarolina da Silva, Tyler S. Twombly, Teppei Morikawa, Sun A. Kim, Yohei Masugi, Keisuke Kosumi, Yan Shi, Mancang Gu, Wanwan Li, Chunxia Du, Yang Chen, Wenbin Li, Hongli Liu, Chenxi Li, Kana Wu, Katsuhiko Nosho, Kentaro Inamura, Akiko Hanyuda, Xuehong Zhang, Marios Giannakis, Andrew T. Chan, Charles S. Fuchs, Reiko Nishihara, Jeffrey A. Meyerhardt, Shuji Ogino,
Evidence suggests that high-level physical activity may potentially reduce cancer mortality through its immune enhancement effect. We therefore hypothesized that survival benefits associated with physical activity might be stronger in colorectal carcinomas with lower immune reaction at diagnosis.Using molecular pathological epidemiology databases of 470 colon and rectal carcinoma cases in the Nurses' Health Study and the Health Professionals Follow-up Study, we assessed the prognostic association ...
Tópico(s): Nutrition and Health in Aging
2018 - Oxford University Press | JNCI Cancer Spectrum
Tsuyoshi Hamada, Jonathan A. Nowak, Yohei Masugi, David A. Drew, Mingyang Song, Yin Cao, Keisuke Kosumi, Kosuke Mima, Tyler S. Twombly, Li Liu, Yan Shi, Annacarolina da Silva, Mancang Gu, Wanwan Li, Katsuhiko Nosho, NaNa Keum, Marios Giannakis, Jeffrey A. Meyerhardt, Kana Wu, Molin Wang, Andrew T. Chan, Edward L. Giovannucci, Charles S. Fuchs, Reiko Nishihara, Xuehong Zhang, Shuji Ogino,
Evidence indicates not only carcinogenic effect of cigarette smoking but also its immunosuppressive effect. We hypothesized that the association of smoking with colorectal cancer risk might be stronger for tumors with lower anti-tumor adaptive immune response.
Tópico(s): Colorectal Cancer Screening and Detection
2018 - Oxford University Press | JNCI Journal of the National Cancer Institute
Shaoqing Shi, Bin Zhou, Yanyun Wang, Yu Chen, Kui Zhang, Kana Wang, Yi Quan, Yaping Song, Li Rao, Lin Zhang,
Recent studies have suggested that RTN4 is a multifunctional gene, including inhibition of axonal regeneration, vascular remodeling, apoptosis, and tumor suppression. The TATC and CAA insertion/deletion polymorphisms of RTN4 3'-UTR have been linked to schizophrenia, depression, and dilated cardiomyopathy. To test whether these two polymorphisms are associated with cervical squamous cell carcinoma (CSCC), in this research, by using polymerase chain reaction-polyacrylamide gel electrophoresis, we determined ...
Tópico(s): Cancer-related Molecular Pathways
2012 - Mary Ann Liebert, Inc. | DNA and Cell Biology
Tsuyoshi Hamada, T. Rinda Soong, Yohei Masugi, Keisuke Kosumi, Jonathan A. Nowak, Annacarolina da Silva, Xinmeng Jasmine Mu, Tyler S. Twombly, Hideo Koh, Juhong Yang, Mingyang Song, Li Liu, Mancang Gu, Yan Shi, Katsuhiko Nosho, Teppei Morikawa, Kentaro Inamura, Sachet A. Shukla, Catherine J. Wu, Levi A. Garraway, Xuehong Zhang, Kana Wu, Jeffrey A. Meyerhardt, Andrew T. Chan, Jonathan N. Glickman, Scott J. Rodig, Gordon J. Freeman, Charles S. Fuchs, Reiko Nishihara, Marios Giannakis, Shuji Ogino,
Inhibitors targeting the PDCD1 (programmed cell death 1, PD-1) immune checkpoint pathway have revolutionized cancer treatment strategies. The TIME (Tumor Immunity in the MicroEnvironment) classification based on tumor CD274 (PDCD1 ligand 1, PD-L1) expression and tumor-infiltrating lymphocytes (TIL) has been proposed to predict response to immunotherapy. It remains to be determined clinical, pathological, and molecular features of TIME subtypes of colorectal cancer. Using 812 colon and rectal carcinoma ...
Tópico(s): Colorectal and Anal Carcinomas
2018 - Landes Bioscience | OncoImmunology
Kenji Fujiyoshi, Juha P. Väyrynen, Jennifer Borowsky, David Papke, Kota Arima, Koichiro Haruki, Junko Kishikawa, Naohiko Akimoto, Tomotaka Ugai, Mai Chan Lau, Simeng Gu, Shanshan Shi, Melissa Zhao, Annacarolina Fabiana Lucia Da Silva, Tyler S. Twombly, Hongmei Nan, Jeffrey A. Meyerhardt, Mingyang Song, Xuehong Zhang, Kana Wu, Andrew T. Chan, Charles S. Fuchs, Jochen K. Lennerz, Marios Giannakis, Jonathan A. Nowak, Shuji Ogino,
BackgroundTumour budding and poorly differentiated clusters (PDC) represent forms of tumour invasion. We hypothesised that T-cell densities (reflecting adaptive anti-tumour immunity) might be inversely associated with tumour budding and PDC in colorectal carcinoma.MethodsUtilising 915 colon and rectal carcinomas in two U.S.-wide prospective cohort studies, and multiplex immunofluorescence combined with machine learning algorithms, we assessed CD3, CD4, CD8, CD45RO (PTPRC), and FOXP3 co-expression patterns ...
Tópico(s): Genetic factors in colorectal cancer
2020 - Elsevier BV | EBioMedicine
Kosuke Mima, Reiko Nishihara, Juhong Yang, Ruoxu Dou, Yohei Masugi, Yan Shi, Annacarolina da Silva, Yin Cao, Mingyang Song, Jonathan A. Nowak, Mancang Gu, Wanwan Li, Teppei Morikawa, Xuehong Zhang, Kana Wu, Hideo Baba, Edward L. Giovannucci, Jeffrey A. Meyerhardt, Andrew T. Chan, Charles S. Fuchs, Zhi Rong Qian, Shuji Ogino,
Prostaglandin-endoperoxide synthase 2 (PTGS2, cyclooxygenase-2; a target of aspirin) produces inflammatory mediator prostaglandin E2 (PGE2), and contributes to colorectal neoplasia development. PTGS2-driven inflammatory responses can induce tumor expression of microRNA MIR21 (miR-21) that can increase local PGE2 level by downregulating PGE2-metabolizing enzymes. We hypothesized that the prognostic association of tumor MIR21 expression level in colorectal carcinoma might depend on inflammatory tumor ...
Tópico(s): RNA modifications and cancer
2016 - American Association for Cancer Research | Clinical Cancer Research
Li Liu, Fred K. Tabung, Xuehong Zhang, Jonathan A. Nowak, Zhi Rong Qian, Tsuyoshi Hamada, Daniel Nevo, Susan Bullman, Kosuke Mima, Keisuke Kosumi, Annacarolina da Silva, Mingyang Song, Yin Cao, Tyler S. Twombly, Yan Shi, Hongli Liu, Mancang Gu, Hideo Koh, Wanwan Li, Chunxia Du, Chen Yang, Chenxi Li, Wenbin Li, Raaj S. Mehta, Kana Wu, Molin Wang, Aleksandar D. Kostic, Marios Giannakis, Wendy S. Garrett, Curtis Hutthenhower, Andrew T. Chan, Charles S. Fuchs, Reiko Nishihara, Shuji Ogino, Edward L. Giovannucci,
Tópico(s): Diverticular Disease and Complications
2018 - Elsevier BV | Clinical Gastroenterology and Hepatology
Musa Abubakar Kana, Min Shi, Jennifer Ahmed, J.M. Ibrahim, Abdullahi Yusuf Ashir, Karimatu Abdullahi, Halima Bello‐Manga, Matthew Taingson, Amina Mohammed-Durosinlorun, Shuaibu Musa, Abdulkadir Musa Tabari, Stephanie J. London,
Despite the high burden of household air pollution from biomass fuel in sub-Saharan Africa, the association of prenatal biomass fuel exposure and birth weight as a continuous variable among term births has not been extensively studied. In this study, our primary aim is to estimate the association between biomass cooking fuel and birth weight among term births in Kaduna, northwestern Nigeria. For replication, we also evaluated this association in a larger and nationally representative sample from ...
Tópico(s): Energy, Environment, and Transportation Policies
2022 - Public Library of Science | PLOS Global Public Health
Shanshan Shi, Kai Wang, Rong Zhong, Aedín Cassidy, Eric B. Rimm, Katharina Nimptsch, Kana Wu, Andrew T. Chan, Edward L. Giovannucci, Shuji Ogino, Kimmie Ng, Jeffrey A. Meyerhardt, Mingyang Song,
Although experimental evidence supports anticancer effects of flavonoids, the influence of flavonoid intake on colorectal cancer (CRC) survival remains unknown. This study aimed to assess the association of postdiagnostic flavonoid intake with mortality. We prospectively assessed the association of postdiagnostic flavonoid intake with CRC-specific and all-cause mortality in 2552 patients diagnosed with stage I–III CRC in 2 cohort studies—the Nurses’ Health Study and the Health Professionals Follow- ...
Tópico(s): Phytochemicals and Antioxidant Activities
2023 - Elsevier BV | American Journal of Clinical Nutrition