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Artigo Revisado por pares

Mónica Martín,

... cross-gender aesthetics in the case of Luca (Shiloh Fernandez) and homosexuality as in the character of Izzy ( ...

Tópico(s): Utopian, Dystopian, and Speculative Fiction

2022 - University of Illinois Press | Journal of Film and Video

Artigo Acesso aberto Revisado por pares

Shiloh Beckerley, Priscilla Fernandez, Chris Matter, Dana E. Wagner, Brandon Tate, Jeff Jordan,

PURPOSE LGBTQ+ young adults smoke at disproportionately higher rates than their non-LGBTQ+ counterparts, but prevention efforts are limited. Furthermore, prior to This Free Life ( TFL), no known campaigns target LGBTQ+ nondaily smokers. In this study Blue Cross and Blue Shield of Minnesota evaluated a local partnership extension of the Food and Drug Administration (FDA) Center for Tobacco Products’ TFL campaign. METHODS The intervention featured a variety of LGBTQ+-tailored events, social/digital media, ...

Tópico(s): Media Influence and Health

2022 - SAGE Publishing | Tobacco Use Insights

Artigo Acesso aberto Revisado por pares

Christian T. Carson,

... as well as 53BP1 (DiTullio et al., 2002; Fernandez-Capetillo et al., 2002), H2AX (Paull et al., 2000), BRCA1, p53 and RPA32 (reviewed in Kastan and Lim, 2000; Shiloh, 2003). Both Mre11 and NBS1 are also targets ...

Tópico(s): Cell death mechanisms and regulation

2003 - Springer Nature | The EMBO Journal

Artigo Acesso aberto Revisado por pares

Michal Meir, Yaron Galanty, Lior Kashani, Michael Blank, Rami Khosravi, María Jesús Fernández-Ávila, Andrés Cruz-García, Ayelet Star, Lea Shochot, Y. Thomas, Lisa Garrett, Daniel Chamovitz, David M. Bodine, Thimo Kurz, Pablo Huertas, Yael Ziv, Yosef Shiloh,

The DNA damage response is vigorously activated by DNA double-strand breaks (DSBs). The chief mobilizer of the DSB response is the ATM protein kinase. We discovered that the COP9 signalosome (CSN) is a crucial player in the DSB response and an ATM target. CSN is a protein complex that regulates the activity of cullin ring ubiquitin ligase (CRL) complexes by removing the ubiquitin-like protein, NEDD8, from their cullin scaffold. We find that the CSN is physically recruited to DSB sites in a neddylation- ...

Tópico(s): Microtubule and mitosis dynamics

2015 - Oxford University Press | Nucleic Acids Research

Artigo Revisado por pares

Dawnyéa D. Jackson, Carolyn A. Stalgaitis, Dana E. Wagner, Shiloh Beckerley, Priscilla Fernandez,

Teen e-cigarette use in the U.S. increased significantly from 2017 to 2018, reversing a trend of declining overall tobacco use. For high school students, current e-cigarette use increased from 11.7% in 2017 to 20.8% in 2018, a staggering 78% increase. Given the effects of nicotine addiction on youth, and the potential association between e-cigarette use and cigarette smoking initiation among youth, it is important to understand which adolescents are at higher risk for e-cigarette use. We sought ...

Tópico(s): School Health and Nursing Education

2020 - Elsevier BV | Journal of Adolescent Health

Artigo Acesso aberto Revisado por pares

Lyuben Tsvetkov, Xingzhi Xu, Jia Li, David F. Stern,

... 10348Google Scholar, 34Matsuoka S. Rotman G. Ogawa A. Shiloh Y. Tamai K. Elledge S.J. Proc. Natl. ... 10348Google Scholar, 34Matsuoka S. Rotman G. Ogawa A. Shiloh Y. Tamai K. Elledge S.J. Proc. Natl. ... in vitro (34Matsuoka S. Rotman G. Ogawa A. Shiloh Y. Tamai K. Elledge S.J. Proc. Natl. ... by ATR (34Matsuoka S. Rotman G. Ogawa A. Shiloh Y. Tamai K. Elledge S.J. Proc. Natl. ... the SCD (34Matsuoka S. Rotman G. Ogawa A. Shiloh Y. Tamai K. Elledge S.J. Proc. Natl. ... in vitro (34Matsuoka S. Rotman G. Ogawa A. Shiloh Y. Tamai K. Elledge S.J. Proc. Natl. ...

Tópico(s): Cancer-related Molecular Pathways

2003 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Nozomi Tomimatsu, Candice Tahimic, Akihiro Otsuki, Sandeep Burma, Akiko Fukuhara, Kenzo Sato, Goshi Shiota, Mitsuo Oshimura, David J. Chen, Akihiro Kurimasa,

... Scopus (1676) Google Scholar, 2Barzilai A. Rotman G. Shiloh Y. DNA Repair (Amst.). 2002; 1: 3-25Crossref ... Lerenthal Y. Moyal L. Andegeko Y. Mittelman L. Shiloh Y. EMBO J. 2003; 22: 5612-5621Crossref PubMed ... Paylor R. Liyanage M. Eckhaus M. Collins F. Shiloh Y. Crawley J.N. Ried T. Tagle D. ... Paylor R. Liyanage M. Eckhaus M. Collins F. Shiloh Y. Crawley J.N. Ried T. Tagle D. ... L. Smorodinsky N.I. Prives C. Reiss Y. Shiloh Y. Ziv Y. Science. 1998; 281: 1674-1677Crossref ... Toledo L.I. Gutierrez-Martinez P. Lopez E. Fernandez-Capetillo O. J. Exp. Med. 2006; 203: 297- ...

Tópico(s): Carcinogens and Genotoxicity Assessment

2007 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Noriko Shirata, Ayumi Kudoh, Tohru Daikoku, Yasutoshi Tatsumi, Masatoshi Fujita, Tohru Kiyono, Yutaka Sugaya, Hiroki Isomura, Kanji Ishizaki, Tatsuya Tsurumi,

... Google Scholar, 7Matsuoka S. Rotman G. Ogawa A. Shiloh Y. Tamai K. Elledge S.J. Proc. Natl. ... Lerenthal Y. Moyal L. Andegeko Y. Mittelman L. Shiloh Y. EMBO J. 2003; 22: 5612-5621Crossref PubMed ... Lerenthal Y. Moyal L. Andegeko Y. Mittelman L. Shiloh Y. EMBO J. 2003; 22: 5612-5621Crossref PubMed ... Lerenthal Y. Moyal L. Andegeko Y. Mittelman L. Shiloh Y. EMBO J. 2003; 22: 5612-5621Crossref PubMed ... carried out by ATM/ATR kinases (39Celeste A. Fernandez-Capetillo O. Kruhlak M.J. Pilch D.R. ...

Tópico(s): Cytomegalovirus and herpesvirus research

2005 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Ayumi Kudoh, Masatoshi Fujita, Lumin Zhang, Noriko Shirata, Tohru Daikoku, Yutaka Sugaya, Hiroki Isomura, Yukihiro Nishiyama, Tatsuya Tsurumi,

... Google Scholar, 8Matsuoka S. Rotman G. Ogawa A. Shiloh Y. Tamai K. Elledge S.J. Proc. Natl. ... Lerenthal Y. Moyal L. Andegeko Y. Mittelman L. Shiloh Y. EMBO J. 2003; 22: 5612-5621Crossref PubMed ... Lerenthal Y. Moyal L. Andegeko Y. Mittelman L. Shiloh Y. EMBO J. 2003; 22: 5612-5621Crossref PubMed ... 34Andegeko Y. Moyal L. Mittelman L. Tsarfaty I. Shiloh Y. Rotman G. J. Biol. Chem. 2001; 276: ...

Tópico(s): Polyomavirus and related diseases

2004 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Elizabeth M. Kass, Jin-Woo Ahn, Tomoaki Tanaka, William A. Freed-Pastor, Susan M. Keezer, Carol Prives,

... Mittelman L. Buscemi G. Okamoto K. Taya Y. Shiloh Y. Jochemsen A.G. Mol. Cell. Biol. 2006; ... Google Scholar, 25Matsuoka S. Rotman G. Ogawa A. Shiloh Y. Tamai K. Elledge S.J. Proc. Natl. ... to 486 (25Matsuoka S. Rotman G. Ogawa A. Shiloh Y. Tamai K. Elledge S.J. Proc. Natl. ... E. Sanchez M. Nayach I. Lopez-Guillermo A. Fernandez P.L. Colomer D. Hernandez L. Campo E. ...

Tópico(s): Cancer-related Molecular Pathways

2007 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Irene M. Ward, Ja‐Eun Kim, Kay Minn, Claudia C.S. Chini, Georges Mer, Junjie Chen,

... L. Smorodinsky N.I. Prives C. Reiss Y. Shiloh Y. Ziv Y. Cell. 2002; 109: 811-821Abstract ... L. Smorodinsky N.I. Prives C. Reiss Y. Shiloh Y. Ziv Y. Science. 2003; 302: 636-639Crossref ... L. Smorodinsky N.I. Prives C. Reiss Y. Shiloh Y. Ziv Y. Science. 2003; 302: 639-642Crossref ...

Tópico(s): Mitochondrial Function and Pathology

2006 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Jodi R. Alt, Alyssa Bouska, Mario R. Fernandez, Ronald L. Cerny, Hua Xiao, Christine M. Eischen,

... Weissman S.M. Lovett M. Collins F.S. Shiloh Y. Science. 1995; 268: 1749-1753Crossref PubMed Scopus ( ... 13Khosravi R. Maya R. Gottlieb T. Oren M. Shiloh Y. Shkedy D. Proc. Natl. Acad. Sci. U. ... Gatti R.A. Shay J.W. Ziv Y. Shiloh Y. Lee E.Y. Nature. 2000; 405: 473- ...

Tópico(s): Epigenetics and DNA Methylation

2005 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Alan Yueh‐Luen Lee, Enbo Liu, Xiaohua Wu,

... Kim Y. Moyal L. Andegeko Y. Mittelman L. Shiloh Y. EMBO J. 2003; 22: 5612-5621Crossref PubMed ... Gatti R.A. Shay J.W. Ziv Y. Shiloh Y. Lee E.Y. Nature. 2000; 405: 473- ...

Tópico(s): Genomics and Chromatin Dynamics

2007 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Ian R. Logan, Vasileia Sapountzi, Luke Gaughan, David E. Neal, Craig Robson,

... Shifman O. Moas M. Buschmann T. Ronai Z. Shiloh Y. Kastan M.B. Katzir E. Oren M. ... p53 upon DNA damage (30Li M. Chen D. Shiloh A. Luo J. Nikolaev A.Y. Qin J. ... Myc (51Frank S.R. Parisi T. Taubert S. Fernandez P. Fuchs M. Chan H.M. Livingston D. ...

Tópico(s): Cancer, Hypoxia, and Metabolism

2004 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Yu-Chi Chiang, Shu‐Chun Teng, Yi‐Ning Su, Fon‐Jou Hsieh, Kou‐Juey Wu,

... Gatti R.A. Shay J.W. Ziv Y. Shiloh Y. Lee E.Y. Nature. 2000; 405: 473- ... as described previously (10Frank S.R. Schroeder M. Fernandez P. Taubert S. Amati B. Genes Dev. 2001; ... cells was performed (10Frank S.R. Schroeder M. Fernandez P. Taubert S. Amati B. Genes Dev. 2001; ...

Tópico(s): Genomics and Chromatin Dynamics

2003 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Ji‐Hye Park, Eun‐Jung Park, Han-Sae Lee, So Jung Kim, Shin-Kyoung Hur, Anthony N. Imbalzano, Jongbum Kwon,

... initiating these intracellular signaling pathways of DSB responses (Shiloh, 2003; Bakkenist and Kastan, 2004). Immediately after DSB ... repair events are facilitated (Bassing and Alt, 2004; Fernandez-Capetillo et al, 2004). Studies using H2AX-deleted ... repair of chromosomal DSBs (Bassing and Alt, 2004; Fernandez-Capetillo et al, 2004). The above results therefore ... after exposure to IR (Burma et al, 2001; Fernandez-Capetillo et al, 2002). ATM exists as an ...

Tópico(s): Cancer therapeutics and mechanisms

2006 - Springer Nature | The EMBO Journal

Carta Acesso aberto Revisado por pares

Leonard Guarente,

... Nbs1 (MRN) complex at the sites of damage (Shiloh and Ziv, 2013Shiloh Y. Ziv Y. Nat. Rev. ... Youn D.Y. Oosterveer M.H. Cen Y. Fernandez-Marcos P.J. Yamamoto H. Andreux P.A. ... Youn D.Y. Oosterveer M.H. Cen Y. Fernandez-Marcos P.J. Yamamoto H. Andreux P.A. ...

Tópico(s): DNA Repair Mechanisms

2016 - Cell Press | Cell Metabolism

Revisão Revisado por pares

Yves Pommier, Malini Gupta, Monica Valenti, Wilberto Nieves‐Neira,

... M. Weissman, M. Lovett, F. S. Collins & Y. Shiloh. 1995. A single ataxia telangiectasia gene with a ...

Tópico(s): DNA and Nucleic Acid Chemistry

1996 - Wiley | Annals of the New York Academy of Sciences

Artigo Acesso aberto Revisado por pares

Tingting Zhang, Carol Prives,

... 52Khosravi R. Maya R. Gottlieb T. Oren M. Shiloh Y. Shkedy D. Proc. Natl. Acad. Sci. U. ...

Tópico(s): Microtubule and mitosis dynamics

2001 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Qin Yang, Anne M. Manicone, Jill D. Coursen, Steven P. Linke, Makoto Nagashima, Marshonna Forgues, Xin Wei Wang,

... Google Scholar, 6Morrow D.M. Tagle D.A. Shiloh Y. Collins F.S. Hieter P. Cell. 1995; ... Ashwell J.D. Rosenberg M.P. Zhan Q. Fernandez-Salguero P.M. Morgan W.F. Deng C. ...

Tópico(s): Microtubule and mitosis dynamics

2000 - Elsevier BV | Journal of Biological Chemistry

Carta Acesso aberto Revisado por pares

Michael Potente, Stefanie Dimmeler,

... Nikolaev AY, Imai S, Chen D, Su F, Shiloh A, Guarente L, Gu W. Negative control of ... 337), Online publication date: 1-Jan-2009. López-Fernández-Sobrino R, Soliz-Rueda J, Ávila-Román J, ...

Tópico(s): Adipose Tissue and Metabolism

2008 - Lippincott Williams & Wilkins | Arteriosclerosis Thrombosis and Vascular Biology

Carta Acesso aberto Revisado por pares

Óscar Fernández-Capetillo, André Nussenzweig,

... A. Noon A.T. Deckbar D. Ziv Y. Shiloh Y. Löbrich M. Jeggo P.A. Mol. Cell. ...

Tópico(s): DNA and Nucleic Acid Chemistry

2008 - Elsevier BV | Molecular Cell

Editorial Acesso aberto Revisado por pares

Jiří Bártek,

... by effects of ionizing radiation) is discussed by Shiloh and colleagues (Rashi-Elkeles et al., 2011). The ... cancer cells, is a topical issue reviewed by Fernandez-Capetillo and colleagues (Toledo et al., 2011). The ...

Tópico(s): PARP inhibition in cancer therapy

2011 - Elsevier BV | Molecular Oncology

Revisão Acesso aberto Revisado por pares

Brendan D. Price, Alan D. D’Andrea,

... A. Noon A.T. Deckbar D. Ziv Y. Shiloh Y. Löbrich M. Jeggo P.A. ATM signaling ...

Tópico(s): DNA and Nucleic Acid Chemistry

2013 - Cell Press | Cell

Artigo Acesso aberto Revisado por pares

Sinan Kilic, Aleksandra Lezaja, Marco Gatti, Eliana Bianco, Jone Michelena, Ralph Imhof, Matthias Altmeyer,

... which phosphorylates histone variant H2AX to generate γH2AX (Shiloh & Ziv, 2013; Blackford & Jackson, 2017). The adaptor protein ... response to DNA damage (DiTullio et al, 2002; Fernandez-Capetillo et al, 2002; Wang et al, 2002; ...

Tópico(s): Genomics and Chromatin Dynamics

2019 - Springer Nature | The EMBO Journal

Artigo Acesso aberto Revisado por pares

... Sherman, L.Sherr, C.Shibayama, H.Shih, I.Shiloh, Y.Shim, H.Shimmura, S.Shimosegawa, T.Shin, ...

Tópico(s): Cancer Mechanisms and Therapy

2012 - American Association for Cancer Research | Molecular Cancer Research

Artigo Acesso aberto Revisado por pares

Francisco Rafael Martins Soto, Isaac Biney, Yasir Akhtar, Peter P. McKeown, J. Francis Turner,

... Text PDF Google Scholar,9Jabbour E. Malik D. Shiloh A.L. Sudden cardiopulmonary collapse in a patient ...

Tópico(s): Cardiac Imaging and Diagnostics

2022 - Elsevier BV | CHEST Journal