Hye‐Young Shin, Chang‐Ho Shin, Tae‐Yong Shin, E. J. Lee, Hyung‐Min Kim,
Bojungikki‐tang (BIT) has been widely used to treat patients suffering from chronic fatigue syndrome (CFS). However, its effect has not been yet investigated experimentally. Based upon the clinical presentation of CFS, we hypothesized that cytokines may play a role in the pathogenesis of the disease. We studied the effect of BIT on lipopolysaccharide (LPS)‐induced various cytokines production in peripheral blood mononuclear cells (PBMC) of CFS patients. Bojungikki‐tang (1 mg/mL) significantly inhibited ...
Tópico(s): Health, psychology, and well-being
2003 - Taylor & Francis | Immunopharmacology and Immunotoxicology
Hye‐Young Shin, Ho-Jeong Na, Phil‐Dong Moon, Taekyun Shin, Tae‐Yong Shin, Sung Hoon Kim, Seung‐Heon Hong, Hyung‐Min Kim,
Tópico(s): Monoclonal and Polyclonal Antibodies Research
2004 - Elsevier BV | Journal of Ethnopharmacology
Sung‐Young Shin, Tae-Yong Kim, Ho-Sung Lee, Jun Hyuk Kang, Ji Young Lee, Kwang‐Hyun Cho, Do Han Kim,
Abstract How cell fate (survival or death) is determined and whether such determination depends on the strength of stimulation has remained unclear. In this study, we discover that the cell fate of cardiomyocytes switches from survival to death with the increase of β-adrenergic receptor (β-AR) stimulation. Mathematical simulations combined with biochemical experimentation of β-AR signalling pathways show that the gradual increment of isoproterenol (a non-selective β 1 /β 2 -AR agonist) induces the switching ...
Tópico(s): Cardiac electrophysiology and arrhythmias
2014 - Nature Portfolio | Nature Communications
Cheol Hong Min, Sangkyun Na, Jae Eun Shin, Tae Yong Kim, Tae Geun Jo, Cheal Kim,
A new Schiff-based multifunctional colorimetric chemosensor 1 was developed for the detection of various analytes (Cu 2+ , Co 2+ and S 2− ).
Tópico(s): Electrochemical sensors and biosensors
2017 - Royal Society of Chemistry | New Journal of Chemistry
Sung‐Jae Kim, Sang-Jin Shin, Tae-Yong Koo,
The authors encountered a case of arch type pathologic suprapatellar plica that was excised using an arthroscopic technique. It is reported with a review of the literature. Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol 17, No 5 (May-June), 2001: pp 536–538
Tópico(s): Shoulder Injury and Treatment
2001 - Elsevier BV | Arthroscopy The Journal of Arthroscopic and Related Surgery
Wytse Hooch Antink, Seongbeom Lee, Hyeon Seok Lee, Heejong Shin, Tae Yong Yoo, Wonjae Ko, Jaehyuk Shim, Geumbi Na, Yung‐Eun Sung, Taeghwan Hyeon,
Abstract High‐entropy spinel oxides (HESOs) are a promising class of electrocatalysts whose material properties and catalytic activity can be finely tuned by controlling the elemental composition. Although numerous HESOs are already reported, their compositions are primarily limited to the first‐row transition metals. Herein, the synthesis of a high‐entropy spinel (CrFeCoNiMo) 3 O 4 nanosheet (HEO‐NS) and its application as oxygen evolution reaction (OER) catalyst are reported. The high‐entropy spinel ...
Tópico(s): High Entropy Alloys Studies
2023 - Wiley | Advanced Functional Materials
Kyun Han, Dae‐Whan Shin, Tae‐Yong Lee, Young‐Ha Lee,
A total of 351 serum samples was examined for anti–T. gondii antibody titers; the overall seroprevalence was 3.7%. The Sabin– Feldman dye test (DT), latex agglutination test (LAT), and IgG enzyme-linked immunosorbent assay (IgG ELISA) indicated seroprevalences of 3.7%, 3.4%, and 4.0%, respectively. Compared with the DT, the sensitivities of the LAT and IgG ELISA were 84.6% and 100.0%, respectively, and the specificities of the LAT and IgG ELISA were both 99.7%. An increase in T. gondii seroprevalence ...
Tópico(s): Pediatric health and respiratory diseases
2008 - American Society of Parasitologists | Journal of Parasitology
Hyunil Kim, Chan Young Cho, Jin Hyun Nam, Dong-Hoon Shin, Tae‐Yong Chung,
A simple dynamic model was proposed to describe the transient output characteristics of polymer electrolyte membrane fuel cells (PEMFCs). Physical parameters for the proposed model were estimated based on the steady and transient results experimentally obtained using a commercial PEMFC (1.2 kW Nexa power module, Ballard Power Systems Inc.). In the transient experiments, the load current was varied according to the high–low current step and the high–low current sweep schedules. The practical applicability ...
Tópico(s): Advanced battery technologies research
2010 - Elsevier BV | International Journal of Hydrogen Energy
In Sook Lee, Yong Beom Shin, Tae-Yong Moon, Yeon Joo Jeong, Jong Woon Song, Dong Hyun Kim,
This study was performed to clarify the cause of shoulder pain using sonography and to evaluate the relationship between the sonographic findings and the motor recovery stages in stroke patients with hemiplegic shoulder pain.Between March 2005 and January 2007, 71 consecutive stroke patients with hemiplegic shoulder pain underwent shoulder sonography. For comparison, bilateral shoulder joints were evaluated in 20 of the 71 patients. The interpretations of the sonographic findings were based on the ...
Tópico(s): Shoulder Injury and Treatment
2009 - American Roentgen Ray Society | American Journal of Roentgenology
Hyunil Kim, Jin Hyun Nam, Dong-Hoon Shin, Tae‐Yong Chung, Young-Gyu Kim,
Computational fluid dynamics (CFD) simulations were conducted to study the liquid water transport behaviors in flow channels of polymer electrolyte membrane fuel cells (PEMFCs). The effects of geometries and surface properties of flow channels on the liquid water exhaust capabilities were quantitatively analyzed based on the exhaust time and stagnant volume data obtained by the CFD simulations. Two different liquid morphologies were found to develop during the two-phase (water/air) transport in flow ...
Tópico(s): Advancements in Solid Oxide Fuel Cells
2009 - Elsevier BV | Current Applied Physics
Sang‐Hyun Kim, Chang‐Duk Jun, Kyongho Suk, Byung‐Ju Choi, Hyunjeung Lim, Seun Ja Park, Seung Ho Lee, Hye‐Young Shin, Daekeun Kim, Tae‐Yong Shin,
The discovery of drugs for the treatment of inflammatory allergic diseases such as, asthma, allergic rhinitis, and sinusitis is a very important subject in human health. Gallic acid (3,4,5-trihydroxybenzoic acid), a polyphenyl natural products from gallnut and green tea, is known to have anti-oxidant, anti-inflammatory, anti-microbial, and radical scavenging activities. The aim of the present study was to elucidate whether gallic acid modulates the inflammatory allergic reaction and to study its ...
Tópico(s): Inflammatory mediators and NSAID effects
2005 - Oxford University Press | Toxicological Sciences
H M. Kim, E H. Lee, Seung‐Heon Hong, Ho-Joon Song, Min Kyung Shin, S H. Kim, Tae‐Yong Shin,
We investigated the effect of aqueous extract of Syzygium aromaticum (L.) Merr. et Perry (Myrtaceae) flower bud (SAFB) on immediate hypersensitivity. SAFB inhibited compound 48/80-induced systemic anaphylaxis in rats (IC50 = 31.25 mg/kg, i.p.). SAFB also inhibited local immunoglobulin E (IgE)-mediated passive cutaneous anaphylactic reaction (IC50 = 17.78 mg/kg, i.v.; IC50 = 19.81 mg/kg, p.o.). When SAFB was pretreated at concentrations ranging from 25 to 1000 mg/kg, the serum histamine levels were reduced in ...
Tópico(s): Allergic Rhinitis and Sensitization
1998 - Elsevier BV | Journal of Ethnopharmacology
Sang‐Hyun Kim, Young-Ee Kwon, Won‐Hwan Park, Hoon Jeon, Tae‐Yong Shin,
... Young-Ee Kwonb, Won-Hwan Parkc*, Hoon Jeond & Tae-Yong Shin*da IHBR, Department of Pharmacology, School of Medicine, ...
Tópico(s): Dermatology and Skin Diseases
2009 - Taylor & Francis | Immunopharmacology and Immunotoxicology
H. M. Kim, Hye Young Shin, K. H. Lim, Sujin Ryu, Tae‐Yong Shin, Han‐Jung Chae, Hyung‐Ryong Kim, Yongqiang Lyu, Nicholas An, Kyu‐Sang Lim,
Substance P (SP) can stimulate production of tumor necrosis factor-α (TNF-α) from astrocytes stimulated with lipopolysaccharide (LPS). The objective of the current study was to determine the effect of Taraxacum officinale (TO) on the production of TNF-α from primary cultures of rat astrocytes. TO (100 and 1000 μg/ml) significantly inhibited the TNF-α production by astrocytes stimulated with LPS and SP. Interleukin-1 (IL-1) has been shown to elevate TNF-α production from LPS-stimulated astrocytes while ...
Tópico(s): Natural product bioactivities and synthesis
2000 - Taylor & Francis | Immunopharmacology and Immunotoxicology
Hye‐Young Shin, Eun‐Hee Lee, Chang‐Young Kim, Tae‐Yong Shin, Sang‐Deok Kim, Yung‐Sun Song, Ki‐Nam Lee, Seung‐Heon Hong, Hyung‐Min Kim,
Purple bamboo salt is a specially processed salt according to the traditional recipe using normal salt and bamboo. It has been used for the purpose of prevention and treatment of various diseases in Korea. We investigated the anti-inflammatory activity of purple bamboo salt by using human mast cell line (HMC-1). Purple bamboo salt (1 mg/mL) inhibited phorbol 12-myristate 13-acetate (PMA) plus calcium ionophore A23187-stimulated tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta and IL-6 secretion, ...
Tópico(s): Polysaccharides and Plant Cell Walls
2003 - Taylor & Francis | Immunopharmacology and Immunotoxicology
Chao‐Long Chen, Yu‐Fan Cheng, Chun‐Yen Yu, Hsin‐You Ou, Leo Leung‐Chit Tsang, Tung‐Liang Huang, Tai-Yi Chen, Allan Concejero, Chih‐Chi Wang, Shih-Ho Wang, Tsan‐Shiun Lin, Yueh‐Wei Liu, Chin‐Hsiang Yang, Chee‐Chien Yong, King‐Wah Chiu, Bruno Jawan, Hock‐Liew Eng, See Ching Chan, William W. Sharr, Chung‐Mau Lo, Sumihito Tamura, Yasuhiko Sugawara, Norihiro Kokudo, Kwang‐Woong Lee, Nam‐Joon Yi, Kyung‐Suk Suh, Deok‐Bog Moon, Sung‐Gyu Lee, Chul‐Soo Ahn, Shin Huang, Ki‐Hun Kim, Tae‐Yong Ha, G.-W Song, Dong‐Hwan Jung, Gil‐Chun Park, Jung-Man Namkoong, Hyung-Woo Park, Yo‐Han Park, Cheon‐Soo Park, Kyw-Bo Sung, Gi‐Young Ko, Dong Il Gwon, T. Kaido, Kohei Ogawa, Yasuhiro Fujimoto, Takashi Ito, Koji Toniyama, Akira Mori, Yasuhiro Ogura, Shinji Üemoto, Anthony Q. Yap, Yu‐Hung Lin, Chunyi Liu, Yuan‐Cheng Chiang, Chih-Chi Lin, Milljae Shin, Jae‐Won Joh, Catherine S. Kabiling, Tsung‐Hui Hu, Sung-Hwa Kang, Bo‐Hyun Jung, Young-Rok Choi,
... Bog; Lee, Sung-Gyu; Ahn, Chul-Soo; Huang, Shin; Kim, Ki-Hun; Ha, Tae-Yong; Song, Gi-Wong; Jung, Dong-Hwan; Park, Gil-Chun; Namkoong, Jung-Man; Park, Hyung-Woo; Park, Yo-Han; Park, Cheon-Soo; Sung, Kyw-Bo; Ko, Gi-Young; Gwon, Dong-Il; Kaido, Toskimi; Ogawa, Kohei; Fujimoto, Yasuhiro; Ito, Takashi; Toniyama, Koji; Mori, Akira; Ogura, Yasuhiro; Uemoto, Shinji; Yap, Anthony Q.; Lin, Yu-Hung; Liu, Chun-Yi; Chiang, Yuan-Cheng; Lin, Chih-Chi; Shin, Milljae; Joh, Jae-Won; Kabiling, Catherine; Hu, Tsung- ...
Tópico(s): Organ Transplantation Techniques and Outcomes
2014 - Wolters Kluwer | Transplantation
Shin Hwang, Tae‐Yong Ha, Gi‐Young Ko, Dong‐Il Kwon, Gi‐Won Song, Dong‐Hwan Jung, Myung‐Hwan Kim, Sung‐Koo Lee, Sung‐Gyu Lee,
Tópico(s): Organ Transplantation Techniques and Outcomes
2015 - Springer Science+Business Media | World Journal of Surgery
Shin Hwang, Tae‐Yong Ha, Gi‐Won Song, Dong‐Hwan Jung, Chul‐Soo Ahn, Deok‐Bog Moon, Ki‐Hun Kim, Young Joo Lee, Sung‐Gyu Lee,
Tópico(s): Liver Disease Diagnosis and Treatment
2015 - Springer Science+Business Media | Journal of Gastrointestinal Surgery
Shin Hwang, Tae‐Yong Ha, Chul‐Soo Ahn, Deok‐Bog Moon, Ki‐Hun Kim, Gi‐Won Song, Dong‐Hwan Jung, Gil‐Chun Park, Sung‐Gyu Lee,
After having experienced more than 2,000 cases of adult living donor liver transplantation (LDLT), we established the concepts of right liver graft standardization. Right liver graft standardization intends to provide hemodynamics-based and regeneration-compliant reconstruction of vascular inflow and outflow. Right liver graft standardization consists of the following components: Right hepatic vein reconstruction includes a combination of caudal-side deep incision and patch venoplasty of the graft ...
Tópico(s): Organ Donation and Transplantation
2016 - | Korean Journal of Hepato-Biliary-Pancreatic Surgery
Seok‐Hwan Kim, Shin Hwang, Tae‐Yong Ha, Gi‐Won Song, Dong‐Hwan Jung, Chul‐Soo Ahn, Deok‐Bog Moon, Ki‐Hun Kim, Gil‐Chun Park, Sung‐Gyu Lee,
Tópico(s): Transplantation: Methods and Outcomes
2015 - Springer Science+Business Media | Journal of Gastrointestinal Surgery
Shin Hwang, Tae‐Yong Ha, Chul‐Soo Ahn, Deok‐Bog Moon, Ki‐Hun Kim, Gi‐Won Song, Dong‐Hwan Jung, Gil‐Chun Park, Jung‐Man Namgoong, Sung-Won Jung, Sam‐Youl Yoon, Kyu‐Bo Sung, Gi‐Young Ko, Byungchul Cho, Kyoung Won Kim, Sung‐Gyu Lee,
Because revascularization of the inferior right hepatic vein (IRHV) is a major component of right liver graft (RLG) reconstruction, we assessed the surgical techniques and clinical outcomes of IRHV reconstruction so that we could formulate practical guidelines for standardized procedures. From July 2004 to February 2010, we performed separate IRHV reconstructions in 487 of 1142 adult RLG recipients (42.7%). These recipients included 364 patients with a natural single IRHV and 123 patients with multiple ...
Tópico(s): Transplantation: Methods and Outcomes
2011 - Lippincott Williams & Wilkins | Liver Transplantation
Shin Hwang, Tae‐Yong Ha, Chul‐Soo Ahn, Deok‐Bog Moon, Gi‐Won Song, Ki‐Hun Kim, Dong‐Hwan Jung, Gil‐Chun Park, Kyu‐Bo Sung, Gi‐Young Ko, Kyoung Won Kim, Byungchul Cho, Jung‐Man Namgoong, Sung-Won Jung, Sam‐Youl Yoon, Chun-Soo Park, Yo‐Han Park, Park Hyeong-woo, Hyo‐Jun Lee, Sung‐Gyu Lee,
Secure reconstruction of the right hepatic vein (RHV) is essential for the successful implantation of a right liver graft during living donor liver transplantation (LDLT). To develop reliable surgical techniques for RHV reconstruction, we performed 3 concurrent studies: a simulation study using a fluid dynamics experimental model and a computational simulation model; an observational study analyzing the hemodynamic changes during radiological interventions for RHV stenosis; and a prospective clinical ...
Tópico(s): Transplantation: Methods and Outcomes
2012 - Lippincott Williams & Wilkins | Liver Transplantation
Shin Hwang, Tae‐Yong Ha, Dong‐Hwan Jung, Jung-Ik Park, Sung‐Gyu Lee,
Tópico(s): Hepatocellular Carcinoma Treatment and Prognosis
2007 - Springer Science+Business Media | Journal of Gastrointestinal Surgery
Sung‐Gyu Lee, Gi‐Won Song, Shin Hwang, Tae Yong Ha, Deok Bog Moon, Dong Hwan Jung, Ki Hun Kim, Chul Soo Ahn, Myung Hwan Kim, Sung Koo Lee, Kyu Bo Sung, Gi Young Ko,
Both curative resection and minimized in-hospital mortality offer the only chance of long-term survival in patients with hilar cholangiocarcinoma. The reported resectability rates for hilar cholangiocarcinoma have increased by virtue of combined major hepatectomy, but this procedure is technically demanding and still associated with a significant morbidity and mortality that must be carefully balanced against the chances of long-term survival.Between January 2001 and December 2008, 350 patients ...
Tópico(s): Gallbladder and Bile Duct Disorders
2009 - Wiley | Journal of Hepato-Biliary-Pancreatic Sciences
Hye‐Young Shin, Sang‐Hyun Kim, Hyun‐Ja Jeong, Sang-Yong Kim, Tae‐Yong Shin, Jae‐Young Um, Seung‐Heon Hong, Hyung‐Min Kim,
<i>Background:</i> Epigallocatechin-3-gallate (EGCG) is a major form of tea catechin and has a variety of biological activities. In the present study, we investigated the effect of EGCG on the secretion of TNF-α, IL-6 and IL-8, as well as its possible mechanism of action by using the human mast cell line (HMC-1). <i>Methods:</i> EGCG was treated before the activation of HMC-1 cells with phorbol 12-myristate 13-acetate (PMA) plus calcium ionophore (A23187). To investigate the effect ...
Tópico(s): Phytochemicals and Antioxidant Activities
2006 - Karger Publishers | International Archives of Allergy and Immunology
Young Ee Kwon, Jung Yul Park, K. T. No, Jae Hong Shin, Sung Kwang Lee, Jae Soon Eun, Jae Heon Yang, Tae Yong Shin, Dae Keun Kim, Byung Sook Chae, Jae-Yoon Leem, Kuk Hwan Kim,
With the goal of developing Alzheimer's disease therapeutics, we have designed and synthesized new piperidine derivatives having dual action of acetylcholinesterase (AChE) and beta-amyloid peptide (Abeta) aggregation inhibition. For binding with the catalytic site of AChE, an ester with aromatic group was designed, and for the peripheral site, another aromatic group was considered. And for intercalating amyloid-beta oligomerization, long and linear conformation with a lipophilic group was considered. ...
Tópico(s): Alzheimer's disease research and treatments
2007 - Elsevier BV | Bioorganic & Medicinal Chemistry
Gil‐Chun Park, Shin Hwang, Tae‐Yong Ha, Gi‐Won Song, Dong‐Hwan Jung, Chul‐Soo Ahn, Deok‐Bog Moon, Ki‐Hun Kim, Young‐In Yoon, Hwui‐Dong Cho, Jae Hyun Kwon, Yong‐Kyu Chung, Sang‐Hyun Kang, I-Ji Jung, Jin-Uk Choi, Sung‐Gyu Lee,
[b]BACKGROUND[/b] Because of the supply shortage for homologous vein allografts, we previously used ringed Gore-Tex vascular grafts for middle hepatic vein (MHV) reconstruction in living donor liver transplantation. However, owing to the subsequent unavailability of ringed Gore-Tex grafts, we replaced them with Hemashield vascular grafts. This study aimed to compare the patency of Hemashield grafts with that of ringed Gore-Tex grafts. [b]MATERIAL AND METHODS[/b] This was a retrospective double-arm ...
Tópico(s): Organ Donation and Transplantation
2019 - International Scientific Information Inc. | Annals of Transplantation
Shin Hye Yoo, Tae‐Yong Kim, Miso Kim, Kyung-Hun Lee, Eun-Shin Lee, Han‐Byoel Lee, Hyeong‐Gon Moon, Wonshik Han, Dong‐Young Noh, Sae‐Won Han, Tae‐You Kim, Seock‐Ah Im,
Introduction A 21-gene prediction assay (Oncotype DX) is helpful to estimate benefit from adjuvant chemotherapy in patients with hormone receptor–positive, lymph node–negative early breast cancer. This study was conducted to develop a model to estimate high recurrence score (RS) using easily available clinicopathologic parameters in limited-resource countries. Patients and Methods Hormone receptor–positive, lymph node–negative early breast cancer patients who underwent Oncotype DX were enrolled onto ...
Tópico(s): Cancer Genomics and Diagnostics
2019 - Elsevier BV | Clinical Breast Cancer
Hye‐Young Shin, Sang‐Hyun Kim, Sin-Myoung Kang, Ik-Jun Chang, Sang-Yong Kim, Hoon Jeon, Kang‐Hyun Leem, Won‐Hwan Park, Jong‐Pil Lim, Tae‐Yong Shin,
Motherwort (MW), a Korean folk medicine, has been applied to treat inflammatory disease. However, its effect on inflammatory cytokine release from mast cells is not well known. We investigated the anti- inflammatory effect of MW on the secretion of inflammatory cytokine such as tumor necrosis factor (TNF)-α and interleukin (IL)-6 and IL-8 in human mast cell line (HMC-1). MW was treated in vitro before activation of HMC-1 cells with phorbol 12-myristate 13-acetate (PMA) plus calcium ionophore A23187. ...
Tópico(s): Dermatology and Skin Diseases
2008 - Taylor & Francis | Immunopharmacology and Immunotoxicology
Shin Hwang, Tae‐Yong Ha, Gi‐Won Song, Dong‐Hwan Jung, Deok‐Bog Moon, Chul‐Soo Ahn, Ki‐Hun Kim, Gil‐Chun Park, Sung‐Gyu Lee,
Tópico(s): Transplantation: Methods and Outcomes
2015 - Springer Science+Business Media | Journal of Gastrointestinal Surgery