Shogo Takamiya, Kazuki Shiotani, Tomoya Ohnuki, Yuma Osako, Yuta Tanisumi, Shoko Yuki, Hiroyuki Manabe, Junya Hirokawa, Yoshio Sakurai,
The hippocampus is crucial for forming associations between environmental stimuli. However, it is unclear how neural activities of hippocampal neurons dynamically change during the learning process. To address this question, we developed an associative memory task for rats with auditory stimuli. In this task, the rats were required to associate tone pitches (high and low) and ports (right and left) to obtain a reward. We recorded the firing activity of neurons in rats hippocampal CA1 during the learning ...
Tópico(s): Neural dynamics and brain function
2021 - Frontiers Media | Frontiers in Systems Neuroscience
Masakazu Saitoh, Haruki Itoh, Nobuo Morotomi, Tetsuya Ozawa, Noriko Ishii, Reina Uewaki, Kentaro Hori, Yohei Shiotani, Miki Ando, Shogo Nakashima, Kana Kawai, Azusa Ohno, Masatoshi Nagayama,
<b><i>Objective:</i></b> The aim of this study was to confirm the effects of chronic kidney disease (CKD) and anemia on physical function and to clarify whether the interaction between CKD and anemia has an additive effect. <b><i>Design:</i></b> Eligible subjects were chronic heart failure (HF) patients who were discharged between March 2007 and August 2009. A total of 102 chronic HF patients (33% females; mean age: 68 ± 14 years) were enrolled in the present ...
Tópico(s): Iron Metabolism and Disorders
2014 - Karger Publishers | Cardiorenal Medicine
Takaomi Kurioka, Takeshi Matsunobu, Yasushi Satoh, Katsuki Niwa, Shogo Endo, Masato Fujioka, Akihiro Shiotani,
Extracellular signal-regulated kinase (ERK) is a member of the family of mitogen-activated protein kinases (MAPKs) and coordinately regulates a multitude of cellular processes. In response to a variety of extracellular stimuli, phosphorylation of both threonine and tyrosine residues activates ERK. Recent evidence indicates that ERK is activated in response to cellular stress such as acoustic trauma. However, the specific role of ERK isoforms in auditory function is not fully understood. Here, we show ...
Tópico(s): Ear Surgery and Otitis Media
2015 - Nature Portfolio | Scientific Reports
Tomoyuki Nishizaki, Toshiyuki Matsuoka, Tamotsu Nomura, Shogo Matsuyama, Shigeo Watabe, Tadashi Shiotani, Mitsunobu Yoshii,
Nefiracetam, a nootropic agent, enhanced the slope of field excitatory postsynaptic potentials in the CA1 region of rat hippocampal slices to about 170% of basal levels, being evident still at 4-h washing-out of the drug. A similar sustained enhancement (>/=16 h after i.m. injection with nefiracetam) was observed in the population spikes recorded from the granular cell layer of the intact mouse hippocampus. Saturation of the enhancement in the synaptic strength occluded potentiation obtained with long- ...
Tópico(s): Photoreceptor and optogenetics research
1999 - Elsevier BV | Brain Research
Shogo Takamiya, Kazuki Shiotani, Tomoya Ohnuki, Yuma Osako, Yuta Tanisumi, Shoko Yuki, Hiroyuki Manabe, Junya Hirokawa, Yoshio Sakurai,
Abstract The activity of primary auditory cortex (A1) neurons is modulated not only by sensory inputs but also by other task-related variables in associative learning. However, it is unclear how A1 neural activity changes dynamically in response to these variables during the learning process of associative memory tasks. Therefore, we developed an associative memory task using auditory stimuli in rats. In this task, rats were required to associate tone frequencies (high and low) with a choice of ports ( ...
Tópico(s): Memory and Neural Mechanisms
2022 - Society for Neuroscience | eNeuro
Tomoya Kobayashi, H Fukuoka, Shogo Suzuki, Seiji Shiotani, Hajime Saitou, Kazuya Tashiro, Satoka Someya, Masahiro Yoshida, Kazunori Kaga, Moyu Yamamori, Katsumi Miyamoto, Hideyuki Hayakawa,
We report the use of unenhanced postmortem computed tomography (PMCT) to visualize the coronary artery in a 45-year-old man who died suddenly. Cardiac PMCT was performed over the same anatomical region, and the individual scans were fused using software for image data summation (fused CT). Cardiac fused PMCT is an innovative imaging method that can clearly delineate the vascular wall of the coronary artery and hypostasis in the lumen, which is not feasible using routine whole-body CT.
Tópico(s): Radiation Dose and Imaging
2020 - Elsevier BV | Forensic Imaging
Takao Shibayama, Shogo Hasegawa, So Nakamura, M Tachibana, Seido Jitsukawa, Akiko Shiotani, S Morinaga,
We describe a 41-year-old Japanese man with metastases of the lung, bone, lymph nodes and the base of the tongue 34 months after right radical nephrectomy. One month after systemic administration of human lymphoblastoid interferon (IFN), the metastasis to the base of the tongue completely disappeared, while other metastases increased both in size and number. Though the true effect of IFN-alpha on the metastatic renal cell carcinoma to the base of the tongue is still unknown, our case indicates that ...
Tópico(s): Oral health in cancer treatment
1993 - Elsevier BV | European Urology
Kenji Sugio, Tatsuro Okamoto, Yoshimasa Maniwa, Yasushi Toh, Morihito Okada, Taku Yamashita, Shogo Shinohara, Ichiro Yoshino, Masayuki Chida, Hiroyuki Kuwano, Akihiro Shiotani,
We aimed to clarify the clinical features and surgical outcomes of descending necrotizing mediastinitis (DNM) to provide a guide for its surgical treatment, focusing on the type of extension and the deployed procedures.As a joint study of the Japan Broncho-esophagological Society and the Japanese Association for Chest Surgery (JBES1703/JACS1806 study), the clinical data of consecutive patients with DNM who underwent surgical drainage between 2012 and 2016 were collected from 131 participating institutions. ...
Tópico(s): Emergency and Acute Care Studies
2021 - Elsevier BV | JTCVS Open
Masakazu Saitoh, Yohei Shiotani, Shogo Nakashima, Reina Uewaki, Kentaro Hori, Tetsuya Ozawa, Kana Kawai, Yuichi Adachi, Yuko Iwasa, Aika KOZONO, Nobuo Morotomi, Masatoshi Nagayama, Morimasa Takayama,
Purpose: The aim of this study was to evaluate the progress of postoperative cardiac rehabilitation and physical function in elderly patients after transcatheter aortic valve replacement (TAVR). Methods: One hundred thirty-nine patients aged over 65 years with severe aortic stenosis (54 males and 85 females, aged 77 ± 7 years) who underwent elective conventional open heart AVR or TAVR were selected and divided into 3 groups; group A (AVR, < 80 years), group B (AVR ≥ 80 years), group C (TAVR). We evaluated ...
Tópico(s): Cardiac Health and Mental Health
2015 - Japan Statistical Society | Journal of the Japanese Physical Therapy Association
Noriyuki Komatsú, Shinichi Yoshimura, Hiroko Toyooka, Kei-ichi Watanabe, Tatsuichi Endo, Michimasa Kato, Masayuki Shinoda, Sadaki Yokota, Shinsuke Kanamura, Kazuo Kanai, Jun Watanabe, Yoshihiko Shugyo, Motoko Oka, Mari Asada‐Kubota, Hiroshi Abe, Toshiharu MATSUMOTO, Yoshiro Fukuda, F. Murata, Toshihiko Suganuma, Shinichiro Tsuyama, N. Enokizono, Shozo NISHIDA, Mitsuyo MAEDA, Eiji KADOTA, Kurenai TANJI, Shigeo HASHIMOTO, Fumiharu AKAI, Yoshikazu Yamaguchi, Masataka Ito, Kuniaki Takata, S. Saito, Toshio Aoyagi, Hiroshi HIRANO, Matsuji Hosaka, N. Murase, Tadashi ORITO, Masahiko Mori, Takahiro Yamagami, E-iti Yokomura, Naonori Sugai, Takeo Oosaki, Seiki SUGINO, Masayoshi Shimazaki, Takehiro Mitsuhashi, Hideki Kuwahara, Yorihiko Chanoki, Takeo SAKAI, Hiroshi Masuda, Yuzo OGAWA, Toshio Yagi, Kazuaki Nakura, Takafumi Yoshioka, Osamu Tanaka, Kenichirou Inomata, Takayuki Akahoshi, Takuma Saito, Akihiro Ohira, Tśuyoshi Soji, Kenji Oshima, Haruki Kiyama, Yayoi Katayama, V.J. Hillyard, I. MacIntyre, P.C. Emson, M Tohyama, Koujiro Tohyama, Reiko Yokota, Chizuka Idé, H. Yamada, Toshiko Nagashima, M Uono, Sadao Shiosaka, Masaya TOHYAMA, Yahē Shiotani, Tomohiro MATSUYAMA, Akio Wanaka, Shotaro Yoneda, Kazufumi Kimura, Yasuhide Lee, Y. LEE, Y. KAWAI, E. TAEAMI, S. GAKA, M.T. HYAMA, Y. SHIOTANI, Shogo Yoshida, Sachiko Hatakenaka, Nobuhiro Miki, Hiroshi Takagi, Yumiko Morishima, Y. Kubota, Shiro Mori, Sachiko Hatakenaka, Naomasa Miki, Rie Miyoshi, Shozo KITO, Kumiko Mizuno, F. Mizukoshi, N. Yasuda, M. Tachibana, O. Mizukoshi, T. Daimon, Kazuhiro Kawai, Kazuko Uchida, T. Murakami, Her-Hsiung Huang, Hiroaki Nakajima, Vinci Mizuhira, Junko Yokofujita, Mika Kubota, Yoshie Sugiura, Yoshio SHIIHA, Yoshoaki SAWADA, Akira Kawaoi, Bin TAKEDA, I Nishiya, Toshihiko Izutsu, T Kagabu, Airo Tsubura, Satoshi Ueda, Sotokichi Morii, Kiyoaki Kitajima, Toshio Yoshida, Yukihiro Noguchi, Tadao Yamamoto, Kiyoki Okada, Yohei Takai, N. Murase, Matsuji Hosaka, Yohko NODA, S SUMITOMO, M. Mori, Noriyuki Sahara, Kazuo Suzuki, Hiroshi Mitani, Keiji Suzuki, Umeko Kawaharada, Nobuaki Ito, Teruo TANAKA, Akira Takahashi,
The pathophisiological significance of rat GSH-PO on various fatty liver and hormonal disorders of adrenal glands was intensively investigated by usage of the immunoperoxidase method established in our laboratory.It is also well documented fact that lipid peroxidation attribute the occurrence of serious pulmonary disease induced by oxidants, radiation etc and/or arteiosclerosis.For the studies of those pulmonary and arteriosclerotic disorders, however, rabbit is allegedly recognized as a superior ...
1984 - Japan Society of Histochemistry and Cytochemistry | ACTA HISTOCHEMICA ET CYTOCHEMICA
H Fukuoka, Shogo Suzuki, Yasuhisa Kono, Seiji Shiotani, Tomoya Kobayashi,
Tópico(s): Medical Imaging Techniques and Applications
2021 - Elsevier BV | Forensic Imaging
Akari Kimura, Koji Araki, Yasushi Satoh, Sachiyo Mogi, Kazuko Fujitani, Takaomi Kurioka, Shogo Endo, Akihiro Shiotani, Taku Yamashita,
Tracheal stenosis is a refractory and recurrent disease induced by excessive cell proliferation within the restricted tracheal space. We investigated the role of extracellular signal-regulated kinase (ERK), which mediates a broad range of intracellular signal transduction processes in tracheal stenosis and the therapeutic effect of the MEK inhibitor which is the upstream kinase of ERK. We histologically analyzed cauterized tracheas to evaluate stenosis using a tracheal stenosis mouse model. Using ...
Tópico(s): Head and Neck Surgical Oncology
2021 - Public Library of Science | PLoS ONE
Masanori Akiyoshi, Shogo Nishida, Masahiro Shiotani, Tadahiro Goda,
Human experts diagnose artifacts by generating fault trees, i. e., finding possible faulty components and their cause-effect relations from observations. Lately such task seems to be much harder, as artifacts become complex. Therefore computational methods, such as model-based reasoning, are expected to cope with the complexity. This paper presents a method of generating fault trees that uses qualitative reasoning. The proposed method deals with “model generation” which relates to the structural ...
Tópico(s): Model-Driven Software Engineering Techniques
1994 - Institute of Electrical Engineers of Japan | IEEJ Transactions on Power and Energy
Gábor Simonyi, Chun-Yao Huang, Yen‐Chung Lin, Yi-Chun Lin, Feng-Yen Lin, Chun-Ming Shih, Kwan‐Dun Wu, T.-C. Chen, Hsi-Hsien Chen, Nen-Chun Chang, Nai-Wen Tsao, Antonietta Gigante, Marta Liberatori, Maria Ludovica Gasperini, Liborio Sardo, Francesca Di Mario, Barbara Dorelli, Biagio Barbano, Edoardo Rosato, Filippo Rossi Fanelli, Antonio Amoroso, Barış Güngör, Şükrü Akyüz, Tuğba Kemaloğlu Öz, Servet Altay, Mehmet Karaca, Barış Yaylak, Selçuk Yazıcı, Güney Erdoğan, Zekeriya Nurkalem, Hülya Kaşıkçıoğlu, Eliécer Coto, Beatriz Tavira, Juan Gómez, Salvador Tranche, Carmen Díaz Corte, Joseph A. Vassalotti, Sarah Sanghavi, Masakazu Saitoh, Tetsuya Ozawa, Kentaro Hori, Reina Uewaki, Yohei Shiotani, Noriko Ishii, Nobuo Morotomi, Haruki Itoh, Miki Ando, Shogo Nakashima, Kana Kawai, Azusa Ohno, Masatoshi Nagayama, Grazia Maria Virzì, Anna Clementi, Alessandra Brocca, Massimo de Cal, Giorgio Vescovo, Antonio Granata, Claudio Ronco, Satz Mengensatzproduktion, Druckerei Stückle, Druckerei Stückle,
2014 - Karger Publishers | Cardiorenal Medicine
Haruhiro Inoue, Hisao Tajiri, Kazuma Fujimoto, Shinsaku Fukuda, Takashi Kawai, Shinji Tanaka, Fujita Kazuhide, Yoshinori Higuchi, Igarashi Hiroyasu, Iishi Kazuo, Inui Atsushi, Irisawa Kato, Takayuki Matsumoto, Kazunari Murakami, Haruhiko Ogata, Akiko Shiotani, Toshiharu Ueki, International Narcotics Control Board, Lars Aabakken, Josep Ramón, Armengol-Miro Francis, Kuang‐Cheng Chan, A. Kadir Dökmeci, Fabián Emura, Kwong‐Ming Fock, Paul Fockens, Norio Fukami, Gregory G. Ginsberg, Khean‐Lee Goh, Robert H. Hawes, Anthony N. Kalloo, Joseph Leung, Horst Neuhaus, Thierry Ponchon, D. Nageshwar Reddy, Jean‐François Rey, Roy Choichi, Sugawa Kok, Yang Tan, Hsiu‐Po Wang, Irving Waxman, Charles F. Wilcox, J. Pablo Arnoletti, Shyam Varadarajulu, Atsushi Irisawa, Hiroshi Miyoshi, Takao Itoi, Shomei Ryozawa, Mitsuhiro Kida, Kentaro Inui, H Osumi, Hiroshi Kawachi, Taku Yoshio, Junko Fujisaki, Manabu Onimaru, Robert Bechara, Mayo Tanabe, M.C. Abad, Akihisa Ueno, Yuto Shimamura, Kazuya Sumi, Hiroaki Ito, Shoji Yoda, Ikuo Yoshinaga, Tetsuro Oda, K Kojima, Hidemi Kato, Taro Daiko, Kevin S. Kolahi, Shmuel Friedland, Christopher E. Louie, Keigo Shibagaki, Yuki Tsuji, Hitoshi Taniguchi, Masahito Aimi, Yoshitaka Miyaoka, Masashi Yuki, Norihisa Ishimura, N. Oshima, Tsuyoshi Mishiro, Y. Tamagawa, Hiromi Mikami, Daisuke Izumi, Nobuko Yamashita, S Sato, Soichiro Ishihara, Yuichiro Kinoshita, Shuji Terao, Saburo Suzuki, Hidemichi Yaita, Koichi Kurahara, Johji Shunto, Takahisa Furuta, Yuki Maruyama, Masaaki Ito, Takenobu Kamada, Ryuta Aoki, Kentaro Inoue, Noriaki Manabe, Ken Haruma, Takeo Yasuda, Tomoyuki Hiroyasu, Satoru Hiwa, Yasunori Okada, Seiji Hayashi, Yuki Nakahata, Yoshinari Yasuda, Takashige Omatsu, Akihiro Obora, Toshiya Kojima, Naoharu Yagi, Akiyoshi Tsuboi, Shiro Oka, Kenji Aoyama, Hideo Saitô, Takuya Aoki, Atsushi Yamada, Takahisa Matsuda, Mitsuhiro Fujishiro, Masato Nakahori, Kazuhiko Koike, Toshifumi Tada, Anthony Yuen Bun Teoh, Amol Bapaye, Sundeep Lakhtakia, Thawee Ratanachu, Rungsun Reknimitr, Stephen Chan, Hyesun Choi, Harshal Gadhikar, Pradermchai Kongkam, S Kumar Korrapati, Y Lee, Jahangeer B. Medarapalem, Wiriyaporn Ridtitid, Jean Moon, Yusuke Kurita, Takamichi Kuwahara, Kenji Hara, Nobumasa Mizuno, Nozomi Okuno, S Matsumoto, Masanori Obata, Hiromu Kōda, Masahiro Tajika, Yūji Shimizu, Ai Nakajima, Kiyoshi Kubota, Yuki Niwa, Ashwin Dalal, G. P. Patil, Amit Maydeo, Atsushi Nakayama, Mototsugu Kato, Yusaku Takatori, Masayuki Shimoda, Mari Mizutani, Kazuhiko Tsutsumi, Yoshiyuki Kiguchi, Teppei Akimoto, Minoru Sasaki, Makoto Mutaguchi, Kaoru Takabayashi, Tadateru Maehata, Yusuke Ochiai, Teruto Kanai, Naohisa Yahagi, Kazuhiro Matsumoto, Shogo Kawano, H Fujiwara, Kozo Nishida, Ryo Harada, Minoru Fujii, Ryochi Yoshida, Yasushi Umeda, Shiro Hinotsu, Takahito Yagi, Hiroyuki Okada, Takehito MORITA, Tomoaki Matsumori, Norimitsu Uza,
Digestive EndoscopyVolume 32, Issue 3 p. 287-289 Issue InformationFree Access Issue Information First published: 06 March 2020 https://doi.org/10.1111/den.13435AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse ...
2020 - Wiley | Digestive Endoscopy