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Primary Document Acesso aberto

Book.

1985 - Gale Group | World Scholar Latin America

Revisão Acesso aberto Revisado por pares

Yanjie Shen, Logan Howard, Xiao‐Ying Yu,

Secondary Ion Mass Spectrometry (SIMS) is an outstanding technique for Mass Spectral Imaging (MSI) due to its notable advantages, including high sensitivity, selectivity, and high dynamic range. As a result, SIMS has been employed across many domains of science. ... in-depth overview of the fundamental principles underlying SIMS, followed by an account of the recent development of SIMS instruments. The review encompasses various applications of specific SIMS instruments, notably static SIMS with time-of-flight ...

Tópico(s): Electron and X-Ray Spectroscopy Techniques

2024 - Multidisciplinary Digital Publishing Institute | Materials

Primary Document Acesso aberto

Book.

1982 - Gale Group | World Scholar Latin America

Artigo Revisado por pares

Kaushik Kuche, Vivek Yadav, M. Dharshini, Rohan Ghadi, Dasharath Chaudhari, Tushar Date, Sanyog Jain,

... the synergistic capacity of sorafenib (SOR) and simvastatin (SIM) to trigger ferroptosis for cancer therapy. For precise in-vivo delivery, SOR + SIM was ratiometrically loaded in bovine serum albumin nanoparticles ( ... phenylboronic acid (CPBA). The developed CPBA-BSA(SOR + SIM)-NPs revealed size of 175.2 ± 12.8 ... 6 ± 4.8 mV. Significantly, CPBA-BSA(SOR + SIM)-NPs exhibited > 2 and > 5-fold reduction in IC50 values compared to individual SOR and SIM treatments respectively, in all tested cell lines. Moreover, CPBA-BSA(SOR + SIM)-NPs treated cells exhibited decrease in glutathione levels, ...

Tópico(s): Cancer Mechanisms and Therapy

2023 - Elsevier BV | International Journal of Biological Macromolecules

Primary Document Acesso aberto

Book.

1962 - Gale Group | World Scholar Latin America

Revisão Acesso aberto Revisado por pares

Xin Chen, Suyi Zhong, Yiwei Hou, Ruijie Cao, Wenyi Wang, Dong Li, Qionghai Dai, Donghyun Kim, Peng Xi,

Structured illumination microscopy (SIM) has become the standard for next-generation wide-field microscopy, offering ultrahigh imaging speed, superresolution, a large field-of- ... and long-term imaging. Over the past decade, SIM hardware and software have flourished, leading to successful ... biological questions. However, unlocking the full potential of SIM system hardware requires the development of advanced reconstruction ... Here, we introduce the basic theory of two SIM algorithms, namely, optical sectioning SIM (OS-SIM) and ...

Tópico(s): Digital Holography and Microscopy

2023 - Springer Nature | Light Science & Applications

Artigo Acesso aberto Revisado por pares

Kaushik Kuche, Vivek Yadav, Meet Patel, Dasharath Chaudhari, Tushar Date, Sanyog Jain,

... the potential of the sorafenib (SOR) and simvastatin (SIM) combination to induce ferroptosis-mediated cancer therapy. To enhance targeted drug delivery, we encapsulated the SOR + SIM combination within 4-carboxy phenylboronic acid (CPBA) modified PLGA nanoparticles (CPBA-PLGA(SOR + SIM)-NPs). The developed CPBA-PLGA(SOR + SIM)-NPs exhibited a spherical shape with a size ... physiological pH. In cellular experiments, CPBA-PLGA(SOR + SIM)-NPs demonstrated remarkable improvements, leading to a 2. ... 5.11-fold decrease in IC50 compared to SIM alone in MDA-MB-231, A549, and HeLa ...

Tópico(s): MicroRNA in disease regulation

2023 - Elsevier BV | Biomaterials Advances

Primary Document Acesso aberto

Book.

1982 - Gale Group | World Scholar Latin America

Artigo Revisado por pares

Xuejing Yang, Wenyu Cao, Xun Gu, Lijie Zheng, Qiuyue Wang, Yingying Li, Fang Wei, Tao Ma, Lu Zhang, Qingqing Wang,

... a drug to a deep wound area. Simvastatin (SIM) can promote wound healing, albeit its insolubility in ... limits its application. Here, we designed a DMNs (SIM-NC@DMNs) drug delivery system loaded with SIM nanocrystals (SIM-NC) and evaluated its efficacy in wound healing. ... on our observations, the dissolution performance of insoluble SIM is significantly improved after the preparation of SIM-NC. For example, the saturation solubility of SIM-NC in deionized water and PBS increased by ... times and 320.14 times, respectively. After the SIM-NC@DMNs are deeply inserted into the wound, ...

Tópico(s): Bee Products Chemical Analysis

2023 - Elsevier BV | International Journal of Pharmaceutics

Primary Document Acesso aberto

Book.

1983 - Gale Group | World Scholar Latin America

Artigo Revisado por pares

Mohamadreza Tavakoli, Hossein Salehi, Rahmatollah Emadi, Jaleh Varshosaz, Sheyda Labbaf, Alexander M. Seifalian, Fariborz Sharifianjazi, Marjan Mirhaj,

... containing 0 or 20 mg/mL of simvastatin (Sim) and then freeze-dried. These scaffolds were named FD and FD-Sim, respectively. Also, similar PLA/HTGO scaffolds were prepared ... solution containing 0 or 20 mg/mL of Sim and were named DC and DC-Sim, respectively. The formation of macro/microporous structure was confirmed by morphological investigations. The release of Sim from DC-Sim and FD-Sim scaffolds after 28 days was measured as 77. ... the highest proliferation, attachment and spread on the Sim containing scaffolds, especially FD-Sim. In vivo studies ...

Tópico(s): Electrospun Nanofibers in Biomedical Applications

2023 - Elsevier BV | International Journal of Biological Macromolecules

Primary Document Acesso aberto

Original Color Book.

1984 - Gale Group | World Scholar Latin America

Artigo Acesso aberto Revisado por pares

Ashish Garg,

... rate scales as <?CDATA $\dot{m}_{\text{flexible}}\sim \alpha^0 $?> m ˙ flexible ∼ α 0 for <?CDATA $(\ ... H o ) ≪ 1 ; <?CDATA $\dot{m}_{\text{flexible}}\sim \alpha $?> m ˙ flexible ∼ α for <?CDATA $(\alpha \Delta pW/EH_o ) \sim O(10^{-1})$?> ( α Δ p W / E ... 10 − 1 ) ; and <?CDATA $\dot{m}_{\text{flexible}}\sim \alpha^3 $?> m ˙ flexible ∼ α 3 for <?CDATA $(\alpha \Delta pW/EH_o) \sim O(1)$?> ( α Δ p W / E H ... channel scales as <?CDATA $\dot{m}_{\text{rigid}}\sim \Delta p $?> m ˙ rigid ∼ Δ p , whereas for ... it scale as <?CDATA $\dot{m}_{\text{flexible}}\sim \Delta p $?> m ˙ flexible ∼ Δ p for <?CDATA $ (\ ... H o ) ≊ 0 , <?CDATA $\dot{m}_{\text{flexible}}\sim \Delta p^2 $?> m ˙ flexible ∼ Δ p 2 ...

Tópico(s): Surface Modification and Superhydrophobicity

2023 - IOP Publishing | New Journal of Physics

Jornais Acesso aberto

From Our Special Correspondent, From Our Squash Rackets Correspondent, Our Rugby Football Correspondent, From Our Billiards Correspondent, William Teeling, J. Ramsbottom, Charles Ponsonby., M. G. Townley., Francis J. A. Towsey., Florence E. Key, Mr. Francis Neilson, Arnold Wilson., George Mitcheson., Herbert G. Williams, A. R. Wise., From Our Aeronautical Correspondent, From Our Correspondent, From Our Own Correspondent, By Callisthenes, From Our League Correspondent, From Our Corresponden, Christopher Turnor., R. G. Stapledon, R. W. Howard, Mr. Burke Downing, Professor Basil Williams, Captain Alfred Instone, From Our Boxing Correspondent, From Our Bridge Correspondent, From Our Astronomical Correspondent, From Our Shipping Correspondent, By C. S. Orwin, , By W. Gavin, By Sir E. John Russell, By Sir Merrik Burrell, By J. F. H. Thomas, By Robert Cobb, By S. J. Wright, By Sir John Orr, By James Mackintosh, By Lord Bingley, By George Dallas, By Sir William Lobjoit, By H. R. Davidson, By Lord Portal, From A Correspondent, By The Hon. Nigel A. Orde-Powlett, By Sir John Stirling-Maxwell, By E. H. B. Boulton, By Lord Eltisley, By Charles Crowther, By J. Basil Buxton, By J. A. S. Watson, By A. H. Burgess, By H. D. Cherry-Downes, By Geraldine Soames, By F. L. Engledow, By E. T. Halnan, By A. W. Menzies-Kitchen, By Charles Prior, By F. L. Sabatini, By P. W. Wilson, By Arthur E. Muskett, By Harry German, From A Special Correspondent, By Captain John Mollett, By H. V. Taylor,

... London Flour Millers Limited, K 4's, Churchill & Sim Limited, Ford Motor Company Ltd., Burberrys Ltd.. News ... Mining News, Pacific Coast Shipping Conference, Churchill And Sim, Japanese War Finance, Argentine Grain Options, Money Market ...

1938 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Ian R. H. Rockett, Haomiao Jia, Bina Ali, Aniruddha Banerjee, Hilary S. Connery, Kurt B. Nolte, Ted R. Miller, F. M. White, Bernard D. DiGregorio, Gregory Luke Larkin, Steven Stack, Kairi Kõlves, R. Kathryn McHugh, Vijay Lulla, Jeralynn S. Cossman, Diego De Leo, Brian Hendricks, Paul S. Nestadt, James H. Berry, Gail D’Onofrio, Eric D. Caine,

Importance Self-injury mortality (SIM) combines suicides and the preponderance of drug misuse–related overdose fatalities. Identifying social and environmental factors associated with SIM and suicide may inform etiologic understanding and intervention design. Objective To identify factors associated with interstate SIM and suicide rate variation and to assess potential ... from the Centers for Disease Control and Prevention, SIM includes all suicides and the preponderance of unintentional ... type. Main Outcomes and Measures The main outcome, SIM, was assessed using unstandardized regression coefficients of interstate ...

Tópico(s): Heme Oxygenase-1 and Carbon Monoxide

2022 - American Medical Association | JAMA Network Open

Jornais Acesso aberto

Jonathan Northcroft, Neil Wornnald, John Dugdale, William Kay, Barbara Hall, Nigel Botherway, Sebastian Faulks, N J, Christopher Higgins, Jim Munro, Peter Whittle, Helen Davies, Sally Brock, Rob Hughes, Jason Dawe, John Peter, Colin Brennan, Professor Gideon Garter, Leonard Gold, David Wilson, Lesley White, Andrew Longmore, Adam Sweeting, Adam Hathaway, Susan d'Arcy, Gareth Walsh, Richard Thomas, Mf Millward, Frank Whitford, Ivo Tennant, John Caulcutt founder of Watermark, David Blunkett, Caroline Brannigan, Sam Gilpin, Kathryn Cooper, Dom Joly, Andrew Taylor, William Lewis, David Silvester, David Smith, Gemma Stockford, Tim Richards, Bob Ganly, Ian Woosnam, Peter McGrath, David Cracknell Political Editor, Nick Pitt, Lucy Hughes-Hallett, Frederic Raphael, E P, Andrew Sullivan, Clive Davis, Andrew Porter, Pane Barrett, Tony Allen-Mills, Simon Wilde, Martin James, Gemma Scott-Martin, Tom Walker, Robert Winnett, Dipesh Gadher Transport Correspondent, Nina Hemstock, Michael Sheridan Ho Chi Minh City, Irwin Stelzer, Matt Rudd, Peter Wilson, Tom Farrall, Rosie Millard, Adrian Furnham, David Dougill, Pat Gilbert, Norman Davies, Robert Winnett Whitehall Correspondent, Mathew Court, Peter Van Stancomb, Stuart Barnes, Peter Jones, Stuart Rand-Bell, Rob Maul, David Hewson, Cally Law, Jonathon Carr-Brown, Hugh Canning, Geraldine Hackett Education Correspondent, Jeremy Clarkson, Victoria Segal, Edward Porter, Phil Spencer, David Cairns, Stewart Lee, Michael Portillo, Sarah Dempster, Ben Martin, Dave Pollard, Cheryl Tweedy, Kevin Jackson, Anita Chaudhuri, Nick Robinson, Richard Fletcher, Greg Struthers, Francis Brown, Phil Craigie, David Carr-Allinson, Jeff Potter, Jeremy Guscott, Sally Murfitt, Peter Parker, Mike Laws, Robin Scott-Elliot, Stuart Wavell, Gary Rhodes, Charles Chesshire, Paul Donovan, Christopher Silvester, Dianne Thompson Chief Executive, Tom Stubbs, Paul Kimmage, Giles Hattersley, Hugh McIlvanney, Chris Woodhead, Bernard Wright, Jasper Gerard, Paul Driver, Simon Davies, Guy Bewick, P D, Nicholas Hellen, Ian Hawkey, Joe Lovejoy football correspondent, Stuart Andrews, Gavin MacDonald, David Leppard, Shelley Von Strunckel, Paul Durman, Tom Avery, Mark Edwards, Tom Shone, Rachel Bridge, Irena Bojanowska, Susan Clark, Simon Jowett, Michael Winner, Peter Whitte, Steven Boyd, Roger Beam, Raymond Keene, C L, Gareth Huw Davies, Rod Liddle, Douglas Alexander, David Cracknell, Cosmo Landesman, Zoe Brennan, Diana Wright, Lindsay Wise Cairo, Nigel Kandzia, Helen Hawkins, Stephen Jones, Dominic O'Connell, Stephen Bleach, Barry Flatman, Uzi Mahnaimi, Nick Cain, Louise Armitstead, Andrew Holgate, Adrienne Connors, Natalie Graham, Caroline Donald, Brian Claridge, Nick Rennison, Rob Ryan, David Carins, Ian Critchley, David Walsh, Jack Grimston, Bryan Appleyard, Stephen Armstrong, John Elliott, Rob Hilliard, Colin McDowell's, Kenny Clemence, Mark Stucklin, Bethan Cole, Roger Panting, McGinty, Richard Woods, Roland White, Ruth Rendell, Shane Watson, Edwina, Amrit Dhillon, Maurice Chittenden, Margaret Clarke, Alex Fortune, Jonathan Clayton, Andy Moore, Judith O'Reilly, Mark Franchetti, Richard Rae, Peter Hunt, Ray Hutton, Dan Box, Clare Francis, Michael Smith, John Harlow, Godfrey Smith, John Cornwell, Roger Bloxham, John Waples, Elahe Mohtasham, Hunter Davies, A A Gill, Alex Pell, Kara O'Reilly, Matthew Campbell, Brian Glanville, Mel Giedroyc, Jeff Peter `, John Carey, David Horspool, Nick Fielding, Stephen Pettitt, Will Iredale, Jonathan Leake Science Editor, Steve Redmond, Jessica Bown, Gareth Davies, Nora Graham, Andrew Marshall, Jeremy Langmead, John Spurling, Sally Kinnes, Tom Pattinson, Naomi Caine, David Wickers, Daniel Emery, Roger Dobson, Brian Doogan, Ben Dowell, Minette Marrin, John Aizlewood, George Davis, Mark Hodson, Simon Kurs, Andrew Frankel, Ken Lunn, Joe Lovejoy, Jonathan Futrell, Graham Norwood, Clifford Bishop, David Budworth, Leslie Law, William Lewis Business editor, Andrew Davidson, Roy Salter, Clive Hetherington, Pete Oliver, Stan Rylett, Arthur Cubley, Hugh Pearman, Dan Cairns, Christopher Bray, Karan Robinson, Hugh Bradley, Alan Sugar, Lord Ezra, Rachel De Thame, Mrs Mills, Sarah Baxter, Brian Schofield, Hugh Robinson, Kate Spicer, Matthew Goodman, India Knight, Sara Hassan, Joanna Simon, Simon Reid, Ed Hughes, Barry Newcombe, Richard Lewis, Sian Griffiths, Karen Robinson, Helen Stewart,

... Model Nokia 7270 — free with contract, or £260 Sim-free from www. livetelecoms. com Strong features, but ... of … Where was I? The New mobile-phone Sim-card firm Sim4travel (0870 … Contents Breaking (and entering) ...

2005 - Gale Group | Sunday Times HA GDA

Artigo Acesso aberto Revisado por pares

Xi Cheng, Jun Li, Qiang Dai, Zhenyong Fu, Jian Yang,

Structured illumination microscopy (SIM) is an important super-resolution-based microscopy technique that breaks the diffraction limit and enhances optical microscopy systems. With ... a high demand for real-time and robust SIM imaging under extreme low-light and short-exposure environments. Existing SIM techniques typically require multiple structured illumination frames to ... In this article, we propose a single-frame SIM (SF-SIM) based on deep learning. Our SF-SIM only needs one shot of a structured illumination ...

Tópico(s): Advanced Fluorescence Microscopy Techniques

2022 - Institute of Electrical and Electronics Engineers | IEEE Transactions on Instrumentation and Measurement

Artigo Acesso aberto Revisado por pares

Siya Jin, Daming Wang, Martyn Hann, Keri Collins, Daniel Conley, Deborah Greaves,

... WEC (D-HRWEC). The open-source tool WEC-Sim is employed in numerical studies. Referring to the ... G-HRWEC, corrections are proposed to the WEC-Sim model which are shown to realise the ability of WEC-Sim to model the two-body hinged WEC. For ... overtopping exist under large oscillations. The updated WEC-Sim model is used to simulate this D-HRWEC ... scale at EMEC site, using the validated WEC-Sim model. The power performance of D-HRWEC is ... dependent on the wave steepness. The updated WEC-Sim is provided and can be directly used to ...

Tópico(s): Coastal and Marine Dynamics

2022 - Elsevier BV | Ocean Engineering