Ana Filipa Duarte, J.N. Maia Silva, Altamiro Costa‐Pereira, Eduardo Nagore, A. Picoto, Osvaldo Correia,
... comSearch for more papers by this authorJ.N. Maia Silva, J.N. Maia Silva Portuguese Skin Cancer Association, Lisboa, PortugalSearch for more ... comSearch for more papers by this authorJ.N. Maia Silva, J.N. Maia Silva Portuguese Skin Cancer Association, Lisboa, PortugalSearch for more ...
Tópico(s): Urban Heat Island Mitigation
2016 - Wiley | Journal of the European Academy of Dermatology and Venereology
Catarina Tomás, Emanuel Oliveira, DANIEL WALLACE ASSIS DE SOUSA, Matheus Uba Chupel, Guilherme Eustáquio Furtado, Clara Rocha, Ana Teixeira, Pedro Lopes Ferreira, C. Alves, Stefan Gisin, Elisabete Catarino, Nelma Carvalho, Tiago Coucelo, Luís Américo Silva Bonfim, Carina Silva, Débora Franco, Jesús Alcoba González, Maria Helena de Agrela Gonçalves Jardim, Rita Silva, Cristina Lavareda Baixinho, Ma Helena Presado, Ma Fátima Marques, Mário E. Cardoso, Marina Cunha, Joana Mendes, Ana Xavier, Ana Galhardo, Margarida Couto, João Frade, Carla Nunes, João R. Mesquita, María Säo José Nascimento, Guilherme Gonçalves, Conceição Castro, Alice Mártires, M. João Monteiro, Conceição Rainho, Francisco P. Caballero, Fátima M. Monago, José T. Guerrero, Rocio M. Monago, Africa P. Trigo, Milagros L. Gutierrez, Gemma M. Milanés, Mercedes G. Reina, Ana G. Villanueva, Ana S. Piñero, Isabel R. Aliseda, Francisco Buitrago Ramírez, Andrea Ribeiro, Ana Quelhas, Maria Conceição Manso, Francisco P. Caballero, José T. Guerrero, Fátima M. Monago, Rafael Brito Santos, Nuria R. Jimenez, Cristina G. Nuñez, Inmaculada Rodríguez Gómez, Ma Jose L. Fernandez, Laura A. Marquez, Ana L. Moreno, Ma Jesus Tena Huertas, Francisco Buitrago Ramírez, Daniel Seabra, Ma Céu Salvador, Luciene Muniz Braga, Pedro Parreira, Anabela Salgueiro‐Oliveira, Cristina Arreguy-Sena, Bibiana F. Oliveira, Ma Adriana Henriques, Joana Santos, Sara Lebre, Alda Marques, Clarinda Festas, Sandra Rodrigues, Andrea Ribeiro, José Lumini‐Oliveira, Ana Gabriela Figueiredo, Francisco J. Hernandez-Martinez, Liliana Campi, Ma Pino Quintana-Montesdeoca, Juan F. Jimenez-Diaz, Bienvenida C. Rodriguez-De-Vera, Alexandra Parente, Ma Augusta Mata, Ana Ma Pereira, Adília Fernandes, Manuel Brás, Ma Rosário Pinto, Pedro Parreira, Marta Lima Basto, Ana C. Rei, Lisete Mónico, Gilberta Sousa, Clementina Morna, Otília Freitas, Gregório Freitas, Ana Carolina Gomes Jardim, Rita P. Vasconcelos, Lina G. Horta, Roger dos Santos Rosa, Luís Fernando Kranz, Rita C. Nugem, Mariana Santiago Siqueira, Ronaldo Bordin, Rosiane Kniess, Josimari Telino de Lacerda, Joana Guedes, Idalina Machado, Sidalina Almeida, Adriano Zilhão, Hélder Alves, Óscar Ribeiro, Ana Paula Martins Amaral, Ana Maria Ribeiro dos Santos, Joana Monteiro, Ma Clara Rocha, Rui Cruz, Ana Paula Martins Amaral, Marina Lourenço, Ma Clara Rocha, Rui Cruz, Sandra Regina Masetto Antunes, Verónica Mendonça, Isabel Andrade, Nádia Osório, Ana Valado, Armando Caseiro, Antonio Padua y Gabriel, Anabela Correia Martins, Fernando Mendes, Lídia Cabral, Manuela Ferreira, Amadeu Gonçalves, Tatiana Durão D`Ávila Luz, Leonardo Gomes de Oliveira Luz, Raúl A. Martins, Alice Murteira Morgado, Maria da Luz Vale-Dias, Rui Porta-Nova, Tânia Cristina Malezan Fleig, Éboni Marília Reuter, Miriam Beatris Froemming, Sabrina Luciane Camara Guerreiro, Lisiane Lisbôa Carvalho, Daniel Guedelha, Pedro S. Coelho, A.T. Pereira, António Calha, Raúl Cordeiro, Ana Gonçalves, Ana Certo, Ana Cristina Araújo de Andrade Galvão, Ma Augusta Mata, Aline Welter, Elayne Crestani Pereira, Sandra Aparecida Ribeiro, Márcia Regina Kretzer, Juan-Fernando Jiménez-Díaz, Carla Jiménez-Rodríguez, Francisco-José Hernández-Martínez, Bienvenida-Del-Carmen Rodríguez-De-Vera, Alexandre Marques-Rodrigues, Patrícia Brazil Pereira Coelho, Tiago Bernardes, Alexandre de Araújo Pereira, Patrícia Sousa, João Ghizzo Filho, Nazaré Otília Nazário, Márcia Regina Kretzer, Odete Amaral, António Garrido, Nélio Veiga, Carla Nunes, Ana Rita Pedro, Carlos Pereira, António Almeia, Hélder Miguel Fernandes, Carlos Vasconcelos, Nélson Sousa, Víctor Machado Reis, M. João Monteiro, Romeu Mendes, Isabel Pinto, Tânia C. S. P. Pires, João Gama, Vera Preto, Norberto Silva, Carlos Pires Magalhães, Matilde Martins, Mafalda Duarte, Constança Paúl, Ignácio Martín, Arminda Pinheiro, S. Xavier, J. Azevedo, E. Bento, C. Marques, M. Marques, A. Macedo, A.T. Pereira, José Pedro Almeida, António Almeida, Josiane Alves, Nélson Sousa, Francisco Saavedra, Romeu Mendes, Ana S. Maia, Michelle Teixeira Oliveira, Anderson Reis de Sousa, Paulo P. Ferreira, Luci S. Lopes, Eujcely C. Santiago, Sílvia Monteiro, Ângelo Jesus, Armanda Colaço, Antônio Ivo de Carvalho, Rita P. Silva, Agostinho Cruz, Ana Ferreira, Catarina Marques, João Paulo Figueiredo, Susana Paix�ão, Ana Ferreira, Carla Lopes, Fernando Moreira, João Paulo Figueiredo, Ana Ferreira, Diana Ribeiro, Fernando Moreira, João Paulo Figueiredo, Susana Paix�ão, Telma Fernandes, Diogo Amado, Jéssica Denise Vieira Leal, Marcelo Costa Velho Mendes de Azevedo, Sónia Ramalho, Catarina Mangas, Jaime Ribeiro, Rita Maria de Abreu Gonçalves, Amélia Fernandes Nunes, Ana Rita Tuna, Carlos Martins, Henriqueta D. Forte, Cláudia Costa, José António Tenedório, Paula Santana, José Augusto Andrade, Joana Pinto, C. Campofiorito, S. C. Nunes, Ana Sofia Carmo, A. Kaliniczenco, BARBARA DE LIMA ALVES, Francisco Mendes, Carlos Jesus, Felipe Paiva Fonseca, Flávia de Sousa Gehrke, Carlos Albuquerque, Rita Carla Pereira Batista, Madalena Cunha, António Dias, Olivério Ribeiro, Rosa Maria Grangeiro Martins, Teresa Madeira, Catarina Peixoto-Plácido, Nuno Rebelo dos Santos, Osvaldo Santos, Astrid Bergland, Asta Bye, Carla Lopes, Violeta Alarcão, Beatriz Goulão, Nuno Mendonça, Paulo Nicola, J. Gorjão Clara, João Gomes, Ana Querido, Catarina Tomás, Daniel Carvalho, Marina Cordeiro, Marlene Rosa, Alda Marques, Daniela Brandão, Óscar Ribeiro, Lia Araújo, Constança Paúl, Beatriz Minghelli, Sylvina Richaud, Ana Laura Mendes, Joana Marta‐Simões, Inês A. Trindade, Cláudia Ferreira, Teresa Carvalho,
... platelet-rich plasma and hyaluronic acid Luís D. Silva, Bruno Maia, Eduardo Ferreira, Filipa Pires, Renato Andrade, Luís Camarinha ... for the treatment of ankle osteoarthritis Luís D. Silva, Bruno Maia, Eduardo Ferreira, Filipa Pires, Renato Andrade, Luís Camarinha ...
BioMed Central
David O. Freedman, P. J. de Almeida Filho, S. Besh, Maria Carmelita Maia e Silva, Cynthia Braga, Anderson Maciel,
... on: Oxford Academic PubMed Google Scholar Maria Carmelita Maia e Silva, Maria Carmelita Maia e Silva Division of Geographic Medicine, University of Alabama at ...
Tópico(s): Lymphatic System and Diseases
1994 - Oxford University Press | The Journal of Infectious Diseases

Marília Araújo da Silva, Noeide da Silva Ferreira, Vinício Heidy da Silva Teixeira-Souza, Camila Maia-Silva, Francisco de Assis de Oliveira, Michael Hrncir,
Stingless bees (Apidae, Meliponini) are frequently used as crop pollinators in tropical countries. The present study calls attention to the thermal limit for the use of these bees as pollinators in commercial greenhouses, in which the temperature frequently exceeds that of the outside environment. We assessed the thermal biology of Melipona subnitida, a stingless bee species that naturally occurs in north-eastern Brazil, a region characterized by elevated ambient temperatures all year round. The ...
Tópico(s): Insect and Arachnid Ecology and Behavior
2017 - Taylor & Francis | Journal of Apicultural Research
Paulo Filipe, Artur M. S. Silva, Raquel S. G. R. Seixas, Diana C. G. A. Pinto, Álvaro da Silva Santos, L. K. Patterson, João Maia Silva, José A. S. Cavaleiro, João Freitas, Jean‐Claude Mazière, René Santús, Patrice Morlière,
It is shown that the relationship between the alkyl chain length of 3-alkyl-3',4',5,7 tetrahydroxyflavones (FnH) bearing alkyl chains of n=1, 4, 6, 10 carbons and their capacity to counter oxidative damage varies markedly with the nature of the biological system. In Cu(2+)-induced lipid peroxidation of low-density lipoprotein (LDL), the less hydrophobic short-chain F1H and F4H are probably located in the outer layer of LDL and parallel the reference flavonoid antioxidant, quercetin (Q) as effective ...
Tópico(s): Synthesis of Organic Compounds
2008 - Elsevier BV | Biochemical Pharmacology
Paulo Filipe, Artur M. S. Silva, Patrice Morlière, Cristela M. Brito, L. K. Patterson, Gordon L. Hug, João Maia Silva, José A. S. Cavaleiro, Jean‐Claude Mazière, João Freitas, René Santús,
Tópico(s): Phytochemicals and Antioxidant Activities
2004 - Elsevier BV | Biochemical Pharmacology
Francisco Caiado, Diogo Maia-Silva, Carolina Jardim, Nina Schmolka, Tânia Carvalho, Cláudia Reforço, Rita Faria, Branka Kolundžija, André E. Simões, Tuncay Baubec, Christopher R. Vakoc, María Gomes da Silva, Markus G. Manz, Ton N. Schumacher, Håkan Norell, Bruno Silva‐Santos,
Abstract Chemotherapy-resistant cancer recurrence is a major cause of mortality. In acute myeloid leukemia (AML), chemorefractory relapses result from the complex interplay between altered genetic, epigenetic and transcriptional states in leukemic cells. Here, we develop an experimental model system using in vitro lineage tracing coupled with exome, transcriptome and in vivo functional readouts to assess the AML population dynamics and associated molecular determinants underpinning chemoresistance ...
Tópico(s): Epigenetics and DNA Methylation
2019 - Nature Portfolio | Nature Communications

José Augusto Salim, Antônio Mauro Saraiva, Paula Zermoglio, Kayna Agostini, Marina Wolowski, Débora Pignatari Drucker, Filipi Miranda Soares, Pedro Joaquim Bergamo, Isabela Galarda Varassin, Leandro Freitas, M. M. Maués, André Rodrigo Rech, Allan Veiga, André Luís Acosta, Andréa Cardoso Araujo, Anselmo Nogueira, Betina Blochtein, Breno Magalhães Freitas, Bruno Albertini, Camila Maia-Silva, Carlos Eduardo Pereira Nunes, C. S. S. Pires, Charles Fernando dos Santos, Elisa Pereira Queiroz, Etienne A Cartolano, Favízia Freitas de Oliveira, Felipe Wanderley Amorim, Francisco E. Fontúrbel, Gleycon Velozo da Silva, Hélder Consolaro, Isabel Alves‐dos‐Santos, Isabel Cristina Machado, Juliana Saragiotto Silva, Kátia P Aleixo, Luísa G. Carvalheiro, Márcia A. Rocca, Mardiore Pinheiro, Michael Hrncir, Nathália Susin Streher, Patrícia Alves Ferreira, Patrícia Maia Correia de Albuquerque, Pietro K. Maruyama, Rafael Cabral Borges, Tereza Cristina Giannini, Vinícius Lourenço Garcia de Brito,
Abstract Background Animal pollination is an important ecosystem function and service, ensuring both the integrity of natural systems and human well-being. Although many knowledge shortfalls remain, some high-quality data sets on biological interactions are now available. The development and adoption of standards for biodiversity data and metadata has promoted great advances in biological data sharing and aggregation, supporting large-scale studies and science-based public policies. However, these ...
Tópico(s): Ecology and Vegetation Dynamics Studies
2022 - University of Oxford | GigaScience
Catarina Sofia Maia Silva, Cândida Pinto, Cristina Araújo Martins,
Resumo Tornar-se pai exige um processo de desenvolvimento pessoal, reorientação interior e adaptação ao novo papel. A literatura sobre este processo tem sido parca, desvalorizando o quão desafiante e problemática pode ser a transição de se tornar pai. Este estudo, de caráter qualitativo, exploratório, descritivo, transversal e retrospetivo procurou compreender as vivências dos homens na transição para a paternidade durante o período pré-natal. Incluiu uma amostra de 10 homens a vivenciar, pela primeira ...
Tópico(s): Male Reproductive Health Studies
2021 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Renee Obringer, Roshanak Nateghi, Debora Maia‐Silva, Sayanti Mukherjee, Vineeth CR, D. Brent McRoberts, Rohini Kumar,
Abstract Soaring temperatures and increased occurrence of heatwaves have drastically increased air‐conditioning demand, a trend that will likely continue into the future. Yet, the impact of anthropogenic warming on household air conditioning is largely unaccounted for in the operation and planning of energy grids. Here, by leveraging the state‐of‐the‐art in machine learning and climate model projections, we find substantial increases in future residential air conditioning demand across the U.S.— ...
Tópico(s): Energy and Environment Impacts
2021 - American Geophysical Union | Earth s Future
Renee Obringer, Benjamin Rachunok, Debora Maia‐Silva, Maryam Arbabzadeh, Roshanak Nateghi, Kaveh Madani,
Tópico(s): Caching and Content Delivery
2021 - Elsevier BV | Resources Conservation and Recycling

Fernando Maia Silva Dias, Thomas J. Riley, Mirna Martins Casagrande, Olaf Hermann Hendrik Mielke,
Memphis Hbner, [1819] is a nymphalid butterfly genus exclusive to the Neotropics. It includes species with iridescent bluish or greenish coloration on the upper side of the wings while the underside is cryptic, resembling dead leaves. This paper aims to describe a remarkable new species, M. smalli Riley Dias sp. nov., from the remote Atlantic slopes of Panama based on molecular and morphological analyses. We also review the taxonomy of species herein included in the arginussa species group based ...
Tópico(s): Genetic diversity and population structure
2021 - Q15088586 | Zootaxa

Camila Miriam Suemi Sato Barros, Raíssa Soares Freire, Elisângela de Fátima Ponte Frota, Anna Gabriela Rezende dos Santos, Maria Eduarda Leão de Farias, Maria Rodrigues, Bernardo Maia Silva, Christiane Maria Prado Jerônimo, Rebeca Linhares Abreu Netto, Mayla Gabriela Silva Borba, Djane Clarys Baía-da-Silva, José Diego Brito-Sousa, Mariana Simão Xavier, Marcia Almeida Araújo-Alexandre, Vanderson de Souza Sampaio, Gisely Cardoso de Melo, Guilherme Tinoco Arêas, Ludhmila Abrahão Hajjar, Wuelton Marcelo Monteiro, Felipe Gomes Naveca, Fábio Trindade Maranhão Costa, Fernando Val, Marcus Lacerda,
Background: The use of corticosteroids may help control the cytokine storm occurring in acute respiratory failure due to the severe form of COVID-19. We evaluated the postacute effect of corticosteroids used during the acute phase, such as impairment in pulmonary function parameters, on day 120 (D120)-follow-up, in participants who survived over 28 days. Methods: This is a parallel, double-blind, randomized, placebo-controlled phase IIb clinical trial carried out between April 18 and October 9, 2020, ...
Tópico(s): Respiratory Support and Mechanisms
2021 - Frontiers Media | Frontiers in Medicine
Tim D.D. Somerville, Yali Xu, Xiaoli Wu, Diogo Maia-Silva, Stella K. Hur, Larissa M. N. de Almeida, Jonathan Preall, Peter K. Koo, Christopher R. Vakoc,
Lineage plasticity is a prominent feature of pancreatic ductal adenocarcinoma (PDA) cells, which can occur via deregulation of lineage-specifying transcription factors. Here, we show that the zinc finger protein ZBED2 is aberrantly expressed in PDA and alters tumor cell identity in this disease. Unexpectedly, our epigenomic experiments reveal that ZBED2 is a sequence-specific transcriptional repressor of IFN-stimulated genes, which occurs through antagonism of IFN regulatory factor 1 (IRF1)-mediated ...
Tópico(s): RNA modifications and cancer
2020 - National Academy of Sciences | Proceedings of the National Academy of Sciences

Camila Maia-Silva, Jaciara da Silva Pereira, Breno Magalhães Freitas, Michael Hrncir,
In hot climates, foraging bees risk overheating during food collection. Here, we investigated influence of ambient temperature on the foraging activity in Melipona subnitida, a stingless bee species that naturally occurs in the hottest and driest regions of the Brazilian tropical dry forest. We observed a decrease in round-trip duration of pollen foragers with increasing ambient temperature. Foraging duration of nectar collectors, however, was not affected by the thermal conditions of the environment. ...
Tópico(s): Insect and Pesticide Research
2020 - Springer Science+Business Media | Apidologie
Catarina Queirós, Pedro Garrido, João Maia Silva, Paulo Filipe,
Photodynamic therapy (PDT) has long been used in dermatology as a therapeutic strategy for several malignant and premalignant conditions. Currently, it is approved in Europe for the treatment of actinic keratosis, squamous cell carcinoma in situ, and some forms of basal cell carcinoma, with favorable clearance rates associated with satisfying aesthetic results. Nonetheless, in the past few years, PDT has also demonstrated efficacy in many other conditions, including inflammatory and infectious dermatoses. ...
Tópico(s): Cutaneous lymphoproliferative disorders research
2020 - Wiley | Dermatologic Therapy

Camila Maia-Silva, Amanda Aparecida Castro Limão, Cláudia Inês da Silva, Vera Lúcia Imperatriz-Fonseca, Michael Hrncir,
Tópico(s): Plant Parasitism and Resistance
2020 - Springer Nature | Neotropical Entomology

Fernando Maia Silva Dias, Diego Rodrigo Dolibaina, Olaf Hermann Hendrik Mielke, Mirna Martins Casagrande,
The “Probetoriformes” species group of Symmachia Hübner, [1819] proposed by Stichel (1910; 1930) is redefined based on morphological evidence, and the species herein included in the group are revised. Two new species from the Brazilian Atlantic Forest are described: S. atlantica Dias, Dolibaina & Mielke sp. nov. and S. uirassu Dolibaina, Dias & Casagrande sp. nov. Additionally, one restituted status, S. championi Godman & Salvin, 1886 stat. rest., one revalidated status, S. belti Godman & Salvin, 1886 stat. ...
Tópico(s): Biological Control of Invasive Species
2020 - Q15088586 | Zootaxa
Rohini Kumar, Benjamin Rachunok, Debora Maia‐Silva, Roshanak Nateghi,
Abstract Current projections of the climate-sensitive portion of residential electricity demand are based on estimating the temperature response of the mean of the demand distribution. In this work, we show that there is significant asymmetry in the summer-time temperature response of electricity demand in the state of California, with high-intensity demand demonstrating a greater sensitivity to temperature increases. The greater climate sensitivity of high-intensity demand is found not only in ...
Tópico(s): Energy and Environment Impacts
2020 - Nature Portfolio | Scientific Reports
Tim D.D. Somerville, Giulia Biffi, Juliane Daßler‐Plenker, Stella K. Hur, Xue‐Yan He, Krysten E. Vance, Koji Miyabayashi, Yali Xu, Diogo Maia-Silva, Olaf Klingbeil, Osama E. Demerdash, Jonathan Preall, Michael A. Hollingsworth, Mikala Egeblad, David A. Tuveson, Christopher R. Vakoc,
A highly aggressive subset of pancreatic ductal adenocarcinomas undergo trans-differentiation into the squamous lineage during disease progression. Here, we investigated whether squamous trans-differentiation of human and mouse pancreatic cancer cells can influence the phenotype of non-neoplastic cells in the tumor microenvironment. Conditioned media experiments revealed that squamous pancreatic cancer cells secrete factors that recruit neutrophils and convert pancreatic stellate cells into cancer- ...
Tópico(s): Immune cells in cancer
2020 - eLife Sciences Publications Ltd | eLife
Debora Maia‐Silva, Rohini Kumar, Roshanak Nateghi,
Abstract Cooling demand is projected to increase under climate change. However, most of the existing projections are based on rising air temperatures alone, ignoring that rising temperatures are associated with increased humidity; a lethal combination that could significantly increase morbidity and mortality rates during extreme heat events. We bridge this gap by identifying the key measures of heat stress, considering both air temperature and near-surface humidity, in characterizing the climate ...
Tópico(s): Energy and Environment Impacts
2020 - Nature Portfolio | Nature Communications

Michael Hrncir, Camila Maia-Silva, Vinício Heidy da Silva Teixeira-Souza, Vera Lúcia Imperatriz-Fonseca,
Tópico(s): Insect and Pesticide Research
2019 - Springer Science+Business Media | Journal of Comparative Physiology A

Emmanuel F. A. Toussaint, Fernando Maia Silva Dias, Olaf Hermann Hendrik Mielke, Mirna Martins Casagrande, Claudia P. Sañudo-Restrepo, Athena Lam, Jérôme Morinière, Michael Balke, Roger Vila,
Our understanding of the origin and evolution of the astonishing Neotropical biodiversity remains somewhat limited. In particular, decoupling the respective impacts of biotic and abiotic factors on the macroevolution of clades is paramount to understand biodiversity assemblage in this region. We present the first comprehensive molecular phylogeny for the Neotropical Anaeini leafwing butterflies (Nymphalidae, Charaxinae) and, applying likelihood-based methods, we test the impact of major abiotic (Andean ...
Tópico(s): Plant and animal studies
2019 - Elsevier BV | Molecular Phylogenetics and Evolution

Shinichi Nakahara, Thamara Zacca, Fernando Maia Silva Dias, Diego Rodrigo Dolibaina, Lei Xiao, Marianne Espeland, Mirna Martins Casagrande, Olaf Hermann Hendrik Mielke, Gerardo Lamas, Blanca Huertas, Kaylin Kleckner, Keith R. Willmott,
We provide the first comprehensive taxonomic revision of the poorly known South American butterfly genus Zischkaia Forster, 1964, hitherto regarded as including three described species. A phylogenetic analysis based on DNA sequence data shows that Zischkaia is monophyletic and consists of two morphologically diagnosable clades. Morphological characters and DNA ‘barcodes’ support the recognition of twelve species in the genus, a significant increase even for the relatively poorly studied subtribe ...
Tópico(s): Plant and animal studies
2019 - Consortium of European Natural History Museums | European Journal of Taxonomy

Carolina Maia Silva, Maria Carolina de Moraes Pereira, Thaís Bernardes de Queiroz, Lucimara Teixeira das Neves,
The cleft lip with or without palate is the most common congenital craniofacial anomaly, presenting prevalence that varies between different ethnicities. It presents a complex and multifactorial etiology which involves genetic and environmental factors. Regarding family history, some studies have observed a significant association among parental consanguinity and orofacial clefts. To investigate if there is an association between parental consanguinity and the occurrence of oral cleft in the offspring. ...
Tópico(s): Oral and Craniofacial Lesions
2019 - Elsevier BV | Early Human Development
Ana B. Oliveira, Miguel Alpalhão, Paulo Filipe, João Maia‐Silva,
Alopecia areata (AA) is a non-scarring alopecia, which often carries a major impact on patients' quality of life. Currently there is no single approved treatment that effectively induces permanent remission. Recently, the JAK-STAT signaling pathway has emerged as a possible therapeutic target leading to increased interest in the use of Janus kinase (JAK) inhibitors (JAKis) in the treatment of this pathology. This review of the literature summarizes information on patients with AA who underwent treatment ...
Tópico(s): Skin and Cellular Biology Research
2019 - Wiley | Dermatologic Therapy
Tim D.D. Somerville, Yali Xu, Koji Miyabayashi, Hervé Tiriac, Cristian R. Cleary, Diogo Maia-Silva, Joseph P. Milazzo, David A. Tuveson, Christopher R. Vakoc,
The aberrant expression of squamous lineage markers in pancreatic ductal adenocarcinoma (PDA) has been correlated with poor clinical outcomes. However, the functional role of this putative transdifferentiation event in PDA pathogenesis remains unclear. Here, we show that expression of the transcription factor TP63 (ΔNp63) is sufficient to install and sustain the enhancer landscape and transcriptional signature of the squamous lineage in human PDA cells. We also demonstrate that TP63-driven enhancer ...
Tópico(s): Epigenetics and DNA Methylation
2018 - Cell Press | Cell Reports

Andressa Rastrelo Rezende, Camille Marques Alves, Isabela Alves Marques, Marco Aurélio Maia Silva, Eduardo Lázaro Martins Naves,
The quantitative measurement of an articular motion is an important indicator of its functional state and for clinical and pathology diagnoses. Joint angle evaluation techniques can be applied to improve sports performance and provide feedback information for prostheses control. Polymer optical fiber (POF) sensors are presented as a novel method to evaluate joint angles, because they are compact, lightweight, flexible and immune to electromagnetic interference. This study aimed to characterize and ...
Tópico(s): Muscle activation and electromyography studies
2018 - Multidisciplinary Digital Publishing Institute | Sensors
Maria João Coimbra-Dores, Mariana Maia-Silva, Wilson Marques, Ana Oliveira, Fernanda Rosa, Deodália Dias,
Tópico(s): Viral Infections and Vectors
2018 - Springer Science+Business Media | Experimental and Applied Acarology

Tereza Cristina Giannini, Camila Maia-Silva, André Luís Acosta, Rodolfo Jaffé, Airton Torres Carvalho, Celso Feitosa Martins, Fernando César Vieira Zanella, Carlos Alfredo Lopes de Carvalho, Michael Hrncir, Antônio Mauro Saraiva, José Oswaldo Siqueira, Vera Lúcia Imperatriz-Fonseca,
In the semiarid region of Northeastern Brazil, populations of native bees can be jeopardized by future climate change. The present study aims to analyze the impact of climate change on a native stingless bee (Melipona subnitida Ducke). This species is a locally important pollinator of wild and crop plants, also exploited for honey production by regional beekeepers. Using species distributional modeling, we assessed the effects of climate change on the geographic distribution of M. subnitida. We found ...
Tópico(s): Insect and Pesticide Research
2017 - Springer Science+Business Media | Apidologie