Jaime Campos Castelló, Silvia Campos Soler,
The epileptic child has three times more risk of presenting cognitive disorders than other children with no neurological pathology, in accordance with three essential facts: 1. The effect exerted by the actual epilepsy. 2. Any associated previously-existing neuropsychosocial deficits. 3. The side effects of the antiepileptic drug (AED). A certain amount of deterioration is universally accepted, without defining the factors involved in its production, but which are multifactorial according to computer ...
Tópico(s): Attention Deficit Hyperactivity Disorder
2004 - Viguera Publishers | Revista de Neurología
Silvia Bozza, Silvia Campo, Brunilde Arseni, Antonio Inforzato, Ragnar Lindstedt, Barbara Bottazzi, Alberto Mantovani, Silvia Moretti, Vasileios Oikonomou, Rita De Santis, Agostinho Carvalho, Giovanni Salvatori, Luigina Romani,
The long pentraxin 3 (PTX3) modulates different effector pathways involved in innate resistance to Aspergillus fumigatus, including complement activation or promotion of phagocytosis by interacting with FcγRs. However, whether and how TLRs modulate PTX3 mediates antifungal resistance is not known. In this study, we demonstrate that PTX3 binds myeloid differentiation protein 2 (MD-2) in vitro and exerts its protective antifungal activity in vivo through TLR4/MD-2-mediated signaling. Similar to Tlr4(-/-) ...
Tópico(s): Leptospirosis research and findings
2014 - American Association of Immunologists | The Journal of Immunology
Pietro Giudice, Silvia Campo, Rita De Santis, Giovanni Salvatori,
This study evaluated the pharmacological activity of PTX3, administered in combination with voriconazole, in a rat model of pulmonary aspergillosis. The data indicated additive therapeutic activities of these compounds, as demonstrated by the amelioration of respiratory function changes, reduction of lung fungal burden, and increased survival. Overall, we provide clear evidence that the combination of PTX3 with a suboptimal dose of voriconazole might represent a therapeutic option under those clinical ...
Tópico(s): Endodontics and Root Canal Treatments
2012 - American Society for Microbiology | Antimicrobial Agents and Chemotherapy
Giovanni Salvatori, Silvia Campo,
Infection caused by Aspergillus fumigatus remains a major therapeutic challenge in immunocompromised individuals. Innate immunity represents the first line of defense against pathogens. In the last 20 years, several proteins belonging to this arm of the immune system have been characterized as being endowed with antifungal activity. Among these, the prototype long pentraxin PTX3 has been identified as a non-redundant protective factor against infections caused by A. fumigatus. A number of relevant ...
Tópico(s): Leptospirosis research and findings
2012 - Oxford University Press | Medical Mycology
Vito Ruggiero, C M D'Urso, Claudio Albertoni, Silvia Campo, Piero Foresta, E. Arrigoni Martelli,
The effect of L-carnitine and some of its acyl derivatives on serum TNF production and lethality in a murine experimental endotoxin shock model was investigated. In some instances, serum IL-6 production was also evaluated. In this experimental model, C57BL/6 mice received 30 mg/kg LPS (E. cell 055:B5) injected intraperitoneally, while L-carnitine and its derivatives were administered according to different schedules. Serum levels of TNF and IL-6 were evaluated 1 h following LPS injection. The treated ...
Tópico(s): Metabolism and Genetic Disorders
1993 - Hindawi Publishing Corporation | Mediators of Inflammation
Produção Nacional
Revisado por pares
Michael Harris Bond, Kwok Leung, Al K. C. Au, Kwok Kit Tong, Sharon Reimel de Carrasquel, Fumio Murakami, Susumu Yamaguchi, Günter Bierbrauer, Theodore M. Singelis, Markus Broer, Filip Boen, Sophie Lambert, Maria Cristina Ferreira, Kimberly A. Noels, Jay Van Bavel, Saba Safdar, Jianxin Zhang, Lina Chen, Iva Šolcová, Iva Stetovska, Toomas Niit, Kaisa‐Kitri Niit, Helena Hurme, Mia Böling, Vijé Franchi, Guguli Magradze, Nino Javakhishvili, Klaus Boehnke, Edgar Klinger, Xu Huang, Márta Fülöp, Mihály Berkics, Penny Panagiotopoulou, Sujata Sriram, Nandita Chaudhary, Anjali Ghosh, Neharika Vohra, Dien Fakhri Iqbal, Jenny Kurman, Ram Thein, Anna Laura Comunian, Kyung Son, Ivars Austers, Charles Harb, Joseph O. T. Odusanya, Zainal A. Ahmed, Rosnah Ismail, Fons van deVijver, Colleen Ward, Andrew Mogaji, David L. Sam, Muhammad Jahan Zeb Khan, William Cabanillas-Rojas, Ly Sycip, Félix Neto, Rosa Cabecinhas, Paulo Ramón Suárez Xavier, Margareta Dincă, Надежда Лебедева, Andrianna Viskochil, О. Я. Пономарева, Steven M. Burgess, Luís Oceja, Silvia Campo, Kwang‐Kuo Hwang, June Bernadette D’souza, Bilge Ataca, Adrian Furnham, J. Rees Lewis,
Leung and colleagues have revealed a five-dimensional structure of social axioms across individuals from five cultural groups. The present research was designed to reveal the culture level factor structure of social axioms and its correlates across 41 nations. An ecological factor analysis on the 60 items of the Social Axioms Survey extracted two factors: Dynamic Externality correlates with value measures tapping collectivism, hierarchy, and conservatism and with national indices indicative of lower ...
Tópico(s): Psychology of Moral and Emotional Judgment
2004 - SAGE Publishing | Journal of Cross-Cultural Psychology
Carmen D’Angelo, Antonella De Luca, Teresa Zelante, Pierluigi Bonifazi, Silvia Moretti, Gloria Giovannini, Rossana G. Iannitti, Silvia Zagarella, Silvia Bozza, Silvia Campo, Giovanni Salvatori, Luigina Romani,
Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by life-threatening bacterial and fungal infections and hyperinflammation. The susceptibility to aspergillosis in experimental CGD (p47(phox-/-) mice) is associated with the failure to control the inherent inflammatory response to the fungus and to restrict the activation of inflammatory Th17 cells. We assessed whether pentraxin (PTX)3, a member of a family of multimeric pattern-recognition proteins with potent anti-Aspergillus ...
Tópico(s): Inflammasome and immune disorders
2009 - American Association of Immunologists | The Journal of Immunology
... preparation of the English version; and Samuel Ballesteros, Silvia Campo, Belén Montes, and Cristina de la Torre for ...
Tópico(s): Social and Intergroup Psychology
2008 - Taylor & Francis | Basic and Applied Social Psychology
Pietro Giudice, Silvia Campo, Antonio Verdoliva, Vincenzo Rivieccio, Franco Borsini, Rita De Santis, Giovanni Salvatori,
Pentraxin 3 (PTX3) is an acute-phase glycoprotein with a nonredundant function in the host resistance to Aspergillus fumigatus. PTX3 activity was evaluated against pulmonary aspergillosis in rats immunosuppressed with cortisone acetate. PTX3 enhanced the survival rate and reduced the lung fungal burden of infected rats in both therapeutic and prophylactic modalities. Thus, we extended the protective activity of PTX3 in pulmonary aspergillosis to corticosteroid-induced immunodeficiency, which is a ...
Tópico(s): Biomarkers in Disease Mechanisms
2010 - American Society for Microbiology | Antimicrobial Agents and Chemotherapy
José Miguel Fernández Dols, Pilar Corrales Aguilar, Silvia Campo, Robin R. Vallacher, Alisha Janowsky, Hugo H. Rabbia, Silvina Brussino, Melvin J. Lerner,
Tópico(s): Emotions and Moral Behavior
2010 - Elsevier BV | Journal of Experimental Social Psychology
Maria Loiarro, Federica Capolunghi, Nicola Fantò, Grazia Gallo, Silvia Campo, Brunilde Arseni, Rita Carsetti, Paolo Carminati, Rita De Santis, Vito Ruggiero, Claudio Sette,
MyD88 is an adaptor protein, which plays an essential role in the intracellular signaling elicited by IL-1R and several TLRs. Central to its function is the ability of its Toll/IL-1R translation initiation region (TIR) domain to heterodimerize with the receptor and to homodimerize with another MyD88 molecule to favor the recruitment of downstream signaling molecules such as the serine/threonine kinases IL-1R-associated kinase 1 (IRAK1) and IRAK4. Herein, we have synthesized and tested the activity ...
Tópico(s): interferon and immune responses
2007 - Oxford University Press | Journal of Leukocyte Biology
Marcela Aracena, Loreto Leiva, Consuelo Undurraga, Mariane Krause, J. Carola Pérez, Victoria Cuadra, MARÍA SILVIA CAMPOS, Paula Bedregal,
Evaluación de la efectividad de programas de visitas domiciliarias para madres adolescentes y sus hijos/as
Tópico(s): Child and Adolescent Psychosocial and Emotional Development
2011 - Q16635223 | Revista médica de Chile
Rita De Santis, Claudio Albertoni, Fiorella Petronzelli, Silvia Campo, Valeria D’Alessio, Antonio Rosi, Anna Maria Anastasi, Ragnar Lindstedt, Nadia Caroni, Brunilde Arseni, Pierino Chiodi, Antonio Verdoliva, Giovanni Cassani, Marco Chinol, Giovanni Paganelli, Paolo Carminati,
Abstract ST2146biot is a biotinylated anti-tenascin monoclonal antibody (mAb) to be used for Pretargeted Antibody Guided Radioimmunotherapy (PAGRIT) of solid tumors. In vivo biodistribution studies of 125I-labeled ST2146biot were done in nude mice transplanted with human HT-29 colon carcinoma and/or human U-118MG glioblastoma cells characterized for low and high tenascin expression, respectively. In vitro results show that ST2146 retains immunoreactivity upon biotinylation, in contrast to other anti- ...
Tópico(s): Cell Adhesion Molecules Research
2006 - American Association for Cancer Research | Clinical Cancer Research
Produção Nacional
Revisado por pares
Nelson Veiga Gonçalves, Ediane Nunes de Araújo, Alcinês da Silva Sousa Júnior, Waltair Maria Martins Pereira, Cláudia do Socorro Carvalho Miranda, Pedro Silvestre da Silvia Campos, Mauro Wendel de Souza Matos, Vera Regina da Cunha Menezes Palácios,
The occurrence of leptospirosis has defied epidemiology even when using different analysis technologies at local geographical levels. This cross-sectional and descriptive study sought to identify spatial correlations between social and environmental risk factors and leptospirosis in Belém in the State of Pará from 2007 to 2013. Epidemiological data were obtained from the Information System for Notifiable Diseases of the Pará State Department of Public Health and the environmental, demographic and ...
Tópico(s): Zoonotic diseases and public health
2016 - ASSOCIAÇÃO BRASILEIRA DE SAÚDE COLETIVA | Ciência & Saúde Coletiva
Produção Nacional
Revisado por pares
Maria Aparecida Shikanai‐Yasuda, Y. M. T. Conceição, Adriana Kono, Evandro A. Rivitti, Aléia Faustina Campos, Sílvia Vidal Campos,
Published studies on the association between cancer and paracoccidioidomycosis consist either isolated cases or clinical data based on hospital cohorts of paracoccidioidomycosis. The frequency of neoplasia in series of ≥80 patients with paracoccidioidomycosis ranges from 0.16 to 14.1%, mean of 3.96%. There are only two retrospective controlled studies, one of them showing greater incidence of carcinoma in biopsy and necropsy samples of paracoccidioidomycosis (12 cases in 147 patients with the mycosis: ...
Tópico(s): Antifungal resistance and susceptibility
2008 - Springer Science+Business Media | Mycopathologia
Silvia Campos-Gutiérrez, María José Ramos-Real, Rossana Abreu, María Soledad Jiménez, María Lecuona,
•Mycobacteria should be included in the study of water from the hospital network. •Mycobacteria can cause infection in patients undergoing invasive processes. •Endoscope reprocessing should be monitored to avoid contamination and transmission. •Multidisciplinary collaboration is essential to detect and control pseudo-outbreaks. Background Mycobacterium fortuitum survive in different environmental conditions, biofilm formation and resistance to chlorinated disinfectants makes its isolation frequent ...
Tópico(s): Infectious Diseases and Mycology
2019 - Elsevier BV | American Journal of Infection Control
Produção Nacional
Revisado por pares
Luciana Monteiro Mendes Martins, Jeane Aparecida Gonzalez Bronzatti, Carmem Silvia de Campos A. Vieira, Silvia Helena Baffi Parra, Yara Boaventura da Silva,
A sobrecarga de trabalho, relacionamento e comunicação, características da Instituição e poluição ambiental foram os agentes estressores organizacionais mais citados neste estudo composto por 30 enfermeiras, sendo que a melhoria no planejamento do trabalho, o aspecto de humanização, adequação dos recursos humanos, melhora na comunicação e educação continuada, dentre outras, foram as sugestões identificadas para melhorar estes agentes estressores. Como agentes estressores extra organizacionais, os ...
Tópico(s): Occupational Health and Burnout
2000 - UNIVERSIDADE DE SÃO PAULO | Revista da Escola de Enfermagem da USP
Sandra Pérez‐Recio, Natàlia Pallarès, Maria D. Grijota‐Camino, Adrián Sánchez‐Montalvá, Laura Barcia, Silvia Campos-Gutiérrez, Virginia Pomar, Ramón Rabuñal-Rey, María Elvira Balcells, Deniz Gazel, Natalia Montiel, Diego Vicente, Ivana Goić-Barišić, Thomas Schön, Jakob Paues, Ivana Mareković, Juana Cacho-Calvo, Aleksandra Barać, Delia Goletti, Mercedes García‐Gasalla, José María Barcala, Teresa Tórtola, Luis Anibarro, Isabel Suárez-Toste, Esther Moga, María José Gude-González, Rodrigo Naves, Tekin Karslığil, Tania Martín-Peñaranda, Goran Stevanović, Matilde Trigo, Verónica Rubio, İlkay Karaoğlan, Nazan Bayram, Fernando Alcaide, Cristian Tebé, Miguel Santín,
We investigated whether the difference of antigen tube 2 (TB2) minus antigen tube 1 (TB1) (TB2-TB1) of the QuantiFERON-TB gold plus test, which has been postulated as a surrogate for the CD8+ T-cell response, could be useful in identifying recent tuberculosis (TB) exposure. We looked at the interferon gamma (IFN-γ) responses and differences in TB2 and TB1 tubes for 686 adults with QFT-plus positive test results. These results were compared among groups with high (368 TB contacts), low (229 patients with ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2021 - American Society for Microbiology | Microbiology Spectrum
Sílvia D. Campos, Rita C. Alves, Eulália Mendes, Anabela S. G. Costa, Susana Casal, M. Beatriz P.P. Oliveira,
Alheiras are a traditional, smoked, fermented meat sausage, produced in Portugal, with an undeniable cultural and gastronomic legacy. In this study, we assessed the nutritional value of this product, as well as the influence of different types of thermal processing. Alheiras from Mirandela were submitted to six different procedures: microwave, skillet, oven, charcoal grill, electric fryer and electric grill. Protein, fat, carbohydrate, minerals, NaCl, and cholesterol contents, as well as fatty acid ...
Tópico(s): Muscle metabolism and nutrition
2012 - Elsevier BV | Meat Science
Eduarda M. Cabral, Telmo J.R. Fernandes, Sílvia D. Campos, M. Castro‐Cunha, M. Beatriz P.P. Oliveira, Luís Miguel Cunha, Luísa M.P. Valente,
The replacement of fish meal (FM) by increasing levels of plant protein (PP) sources 50% (PP50), 75% (PP75) and 100% (PP100) was compared to a control diet (FM) containing fish meal as the main protein source in ongrowing Senegalese sole (mean initial body weight:106 g ± 15). These four diets were isonitrogenous and isolipidic (54% crude protein and 9% crude fat on a dry matter basis). By the end of the growth trial, groups fed PP50 and PP75 had a final body weight and daily growth index (DGI) similar to the ...
Tópico(s): Animal Nutrition and Physiology
2012 - Elsevier BV | Aquaculture
Mohamed A. Saleh, Ruben M. Sandoval, George Rhodes, Silvia B. Campos-Bilderback, Bruce A. Molitoris, David M. Pollock,
We have previously found that chronic endothelin-1 (ET-1) infusion in Sprague-Dawley rats increases glomerular permeability to albumin (P(alb)) as assessed in vitro independent of blood pressure with no observed albuminuria. In this study, we hypothesized that ET-1 increases glomerular albumin filtration with accompanied increase in albumin uptake via the proximal tubule, which masks the expected increase in urinary albumin excretion.
Tópico(s): Ion Transport and Channel Regulation
2012 - Elsevier BV | Life Sciences
Produção Nacional
Revisado por pares
Tânia Mara Varejão Strabelli, Rinaldo Focaccia Siciliano, Sílvia Vidal Campos, Jussara Bianchi Castelli, Fernando Bacal, Edimar Alcides Bocchi, David Éverson Uip,
Toxoplasma gondii primary infection/reactivation after solid organ transplantation is a serious complication, due to the high mortality rate following disseminated disease. We performed a retrospective study of all cases of T. gondii infections in 436 adult patients who had received an orthotopic cardiac transplant at our Institution from May 1968 to January 2011. Six patients (1.3%) developed T. gondii infection/reactivation in the post-operative period. All infections/reactivations occurred before ...
Tópico(s): Herpesvirus Infections and Treatments
2012 - Hindawi Publishing Corporation | Journal of Tropical Medicine
Sharon Ashworth, Sarah E. Wean, Sílvia B. Campos, Constance J. Temm‐Grove, Erica L. Southgate, Bernadette Vrhovski, Peter W. Gunning, Ron P. Weinberger, Bruce A. Molitoris,
Ischemic-induced cell injury results in rapid duration-dependent actin-depolymerizing factor (ADF)/cofilin-mediated disruption of the apical microvilli microfilament cores. Because intestinal microvillar microfilaments are bound and stabilized in the terminal web by the actin-binding protein tropomyosin, we questioned whether a protective effect of tropomyosin localization to the terminal web of the proximal tubule microfilament cores is disrupted during ischemic injury. With tropomyosin-specific ...
Tópico(s): Ion channel regulation and function
2004 - American Physical Society | AJP Renal Physiology
Produção Nacional
Revisado por pares
João Nóbrega de Almeida, Sílvia Vidal Campos, Danilo Yamamoto Thomaz, Luciana Thomaz, Renato K. G. de Almeida, Gilda Maria Bárbaro Del Negro, Viviane F. Gimenes, Rafaella C. Grenfell, Adriana Lopes Motta, Flávia Rossi, Gil Benard,
In 1968, Buckley and van Uden described the non-fermenting yeast Candida blankii (C. blankii) found in the organs of a mink1. Until recently, this microorganism had only been the subject of biotech...
Tópico(s): Antifungal resistance and susceptibility
2018 - Taylor & Francis | Emerging Microbes & Infections
G. Hubert, Gustavo Cordeiro, Geert Vanhooren, Bojana Žvan, Silvia Tur Campos, А. М. Алашеев, Sònia Abilleira, Francesco Corea,
Lack of stroke specialists determines that many European rural areas remain underserved. Use of telemedicine in stroke care has shown to be safe, increase use of evidence-based therapy and enable coverage of large areas of low population density. The aim of this article is to summarise the following recommendations of the Telestroke Committee of the European Stroke Organisation on the setup of telestroke networks in Europe: Hospitals participating in telestroke networks should be chosen according ...
Tópico(s): Telemedicine and Telehealth Implementation
2018 - SAGE Publishing | European Stroke Journal
Leo A. Sapirstein, Donald G. Vidt, Morris J. Mandel, Gordon E. Hanusek,
... rate in the ratExing Wang, Ruben M. Sandoval, Silvia B. Campos, and Bruce A. Molitoris1 November 2010 | American Journal ...
Tópico(s): Pediatric Urology and Nephrology Studies
1955 - American Physiological Society | American Journal of Physiology-Legacy Content
WM Deen, DA Maddox, C R Robertson, Brenner Bm,
... ⅚ nephrectomyNicholas Ferrell, Ruben M. Sandoval, Aihua Bian, Silvia B. Campos-Bilderback, Bruce A. Molitoris, and William H. Fissell15 ...
Tópico(s): Pancreatic function and diabetes
1974 - American Physiological Society | American Journal of Physiology-Legacy Content
Miguel Á. Olvera‐Novoa, Silvia G. Campos, Mirna G. Sabido, Carlos A. Martínez‐Palacios,
Chloroplastic and cytoplasmic alfalfa (Medicago sativa) leaf protein concentrates were tested as dietary replacements for fish meal in practical diets for tilapia fingerlings. Each concentrate was used to replace 15, 25, 35, 45 and 55% of the fish meal protein in diets containing 40% protein. Diets containing cytoplasmic leaf protein gave the best results, with growth rates higher than those obtained with a fish meal-based diet when the plant protein replaced up to 35% of the fish meal protein in ...
Tópico(s): Reproductive biology and impacts on aquatic species
1990 - Elsevier BV | Aquaculture
Leileata M. Russo, Ruben M. Sandoval, Sílvia B. Campos, Bruce A. Molitoris, Wayne D. Comper, Dennis Brown,
Understanding the pathogenesis of albuminuria in diabetic nephropathy is important to improve methods for early diagnosis and treatment. In this study, we addressed whether albuminuria in diabetes results from altered glomerular filtration and/or altered processing of filtered albumin by the proximal tubule. Type 1 diabetic Munich Wistar rats developed albuminuria after 12 wk of diabetes. Intravital two-photon microscopy revealed similar glomerular permeability in the diabetic and control animals, ...
Tópico(s): Advanced Glycation End Products research
2009 - American Society of Nephrology | Journal of the American Society of Nephrology
Flávia de Oliveira, Ricardo Bragança de Vasconcellos Fontes, Josemberg da Silva Baptista, William Paganini Mayer, Silvia de Campos Boldrini, Édson Aparecido Liberti,
The adductor canal is a conical or pyramid-shaped pathway that contains the femoral vessels, saphenous nerve and a varying amount of fibrous tissue. It is involved in adductor canal syndrome, a claudication syndrome involving young individuals. Our objective was to study modifications induced by aging on the connective tissue and to correlate them to the proposed pathophysiological mechanism. The bilateral adductor canals and femoral vessels of four adult and five fetal specimens were removed en ...
Tópico(s): Bone fractures and treatments
2009 - Wiley | Journal of Anatomy