Limpar
298.810 resultados

Acesso aberto

Tipo do recurso

Tipo de base de dados

Ano de criação

Produção nacional

Revisado por pares

Áreas

Idioma

Editores

Primary Document Acesso aberto

Barbauld, Mrs. (Anna Letitia),

Attributed to Anna Letitia Barbauld.--NUC pre-1956. Book.

0000 - Gale Group | The Making of Modern World

Artigo Revisado por pares

Pimchanok Tumree, Anurak Bunnoy, Xiaoqian Tang, Prapansak Srisapoome,

... based monovalent and bivalent vaccines containing S. iniae (Sin) and F. covae (Fco) delivered by top-dressed ... booster administration with high detection levels in the Sin-IP and Fco-IP groups. Moreover, the immune responses to the injected monovalent vaccines (Sin-IP and Fco-IP) were better than the ... and innate immunological parameters were significantly increased by Sin-IP and Fco-IP, particularly lysozyme activity, nitroblue ... 0.05). After experimental challenge, survival in the Sin-IP and Fco-IP groups was significantly higher ...

Tópico(s): Aquaculture Nutrition and Growth

2023 - Elsevier BV | Fish & Shellfish Immunology

Revisão Revisado por pares

Juan-Min Li, Yun-Da Yao, Jin-Fang Luo, Jianxin Liu, Linlin Lu, Zhongqiu Liu, Yan Dong, Ying Xie, Hua Zhou,

Sinomenine (SIN) is the main pharmacologically active component of Sinomenii Caulis and protects against rheumatoid arthritis (RA). In recent ... been conducted to elucidate the pharmacological mechanisms of SIN in the treatment of RA. However, the molecular mechanism of SIN in RA has not been fully elucidated. To summarize the pharmacological effects and molecular mechanisms of SIN in RA and clarify the most valuable regulatory mechanisms of SIN to provide clues and a basis for basic ... that most of the known pharmacological mechanisms of SIN are indirect effects on certain signaling pathways or ...

Tópico(s): Drug Transport and Resistance Mechanisms

2023 - Elsevier BV | Phytomedicine

Artigo Revisado por pares

Jianming Xu, Haiping Jiang, Yueyin Pan, Kangsheng Gu, Shundong Cang, Lei Han, Yongqian Shu, Jiayi Li, Junhui Zhao, Hongming Pan, Suxia Luo, Yanru Qin, Qunyi Guo, Yuxian Bai, Ling Yang, Yingmei Guo, Yuling Chen, Yan Wang, Hui Zhou,

... Background: The phase III ORIENT-16 trial evaluated sin (a PD-1 inhibitor) versus placebo plus chemo ... treatment in pts with advanced G/GEJ adenocarcinoma. Sin+chemo previously showed a significant improvement in OS ... expression. Pts were randomized 1:1 to receive sin (3 mg/kg in pts weighing <60 ... a median follow-up of 33.9 m, sin+chemo continued to show OS benefit over chemo ... OS rates at 24 and 36 m for sin+chemo vs chemo were 37.6% vs 20. ... 0% vs 10.7%, respectively. OS benefits with sin+chemo vs chemo across subgroups were generally consistent ...

Tópico(s): Esophageal Cancer Research and Treatment

2023 - American Association for Cancer Research | Cancer Research

Livro

National Bureau of Economic Research (NBER)

Monograph Acesso aberto

Scudder Klyce, Warren D. Mohr,

Copyright Date from t. p. Verso.; Half-Title.; Bound in Black Cloth, with Black and Red Dust Jacket Includes Bibliographical References and Index.; Preface-- ...

1925 - Gale Group | NCCO SciTechMed 2 of 2

Artigo Acesso aberto Revisado por pares

Moritz Lenschow, Maximilian Lenz, Niklas von Spreckelsen, Julian Ossmann, Johanna Meyer, Julia Keßling, Lukas Nadjiri, Sergej Telentschak, Kourosh Zarghooni, P. Knöll, Moritz Perrech, Eren Celik, Max J. Scheyerer, Volker Neuschmelting,

... spinal instability using the spinal instability neoplastic score (SINS) frequently guides surgical therapy in spinal epidural osseous ... However, how to surgically manage ‘impending instability’ at SINS 7–12 most appropriately remains uncertain. This study ... the necessity of spinal instrumentation in patients with SINS 7–12 with regards to neurological outcome. Methods: ... treated at our interdisciplinary spine center. The preoperative SINS was assessed to determine spinal instability and neurological ... compared. Additionally, a subgroup analysis of groups with SINS of 7–9 and 10–12 was performed. ...

Tópico(s): Spinal Fractures and Fixation Techniques

2022 - Multidisciplinary Digital Publishing Institute | Cancers

Primary Document Acesso aberto

Maxwell, Maria.,

Added engraved t.p. has subtitle: a tale of New York life. Book.

0000 - Gale Group | Sabin

Artigo Revisado por pares

Zhendong Liu, Ruizhou Liu, Rui Wang, Jihang Dai, Hui Chen, Jingcheng Wang, Xiaolei Li,

... joint degeneration in the pathogenesis of OA. Sinensetin (SIN) is a natural flavonoid with anti-inflammatory and ... This study aims to investigate the effect of SIN on OA. We have investigated the anti-inflammatory and chondroprotective effects of SIN on IL-1β-induced human OA chondrocytes and ... IL-1β and treated with different concentrations of SIN. The results suggest that SIN can inhibit IL-1β-induced overproduction of pro- ... the degradation of the extracellular matrix. In addition, SIN can inhibit the activation of NF-κB by ...

Tópico(s): Inflammatory mediators and NSAID effects

2022 - Royal Society of Chemistry | Food & Function

Artigo Revisado por pares

Kouadio Jean Eric‐Parfait Kouamé, Awa Fanny Massounga Bora, Xiaodong Li, Yue Sun, Songfan Tian, Muhammad Altaf Hussain, Lu Liu, Ibourahema Coulibaly,

... the potential of using sodium alginate and inulin (SIN) in combination with various encapsulating materials such as ... of the product were performed. The produced microcapsules (SIN-PRO-SKIM, SIN-PRO-WP, and SIN-PRO-SP) and co-microcapsules (SIN-PRO-FS-SKIM, SIN-PRO-FS-WP, and SIN-PRO-FS-SP) had a high encapsulation rate > ... viability accounting for 9.24 log10 CFU/g (SIN-PRO-SKIM), 8.96 log10 CFU/g (SIN-PRO-WP), and 8.74 log10 CFU/g (SIN-PRO-SP) for encapsulated and 10.08 log10 ...

Tópico(s): Proteins in Food Systems

2022 - Wiley | Journal of Food Science

Primary Document Acesso aberto

Mather, Increase,

Title within mourning border. "Preached at Boston, October 7, 1711."--p. 36. Book.

0000 - Gale Group | Sabin

Artigo Acesso aberto Revisado por pares

Jueting Zheng, Wenli Gao, Taige Lu, Lijue Chen, Luchun Lin, Ruiyun Huang, Yongxiang Tang, Gang Dong, Junyang Liu, Yifei Pan, Wengui Weng, Wenjing Hong,

... irradiation of SSP,38 and a reference molecule SIN-Ref further suggest that the highest conductance value ... 13C NMR, and mass spectrometry) of SSP and SIN-Ref compounds are listed in the Supporting Information ... We also designed and synthesized the reference molecule, SIN-Ref, which contains the indoline structure but is ... in Figure 3a. We measured SMC-UV and SIN-Ref junctions with the same methodology and observed ... to that of Cluster 1 in SSP and SIN-Ref. The 2D conductance-distance histograms of SMC- ...

Tópico(s): Molecular Junctions and Nanostructures

2022 - Chinese Chemical Society | CCS Chemistry

Artigo Revisado por pares

Ke Xu, Miao Du, Lei Hao, Jing Mi, Yang Lin, Shuai Li, Jining Wang, Xueyuan Deng,

SiN/Ag/SiN heat reflecting coatings were prepared by radio frequency reactive magnetron sputtering on glass substrates. Properties of the coatings ... morphology, microstructure and element distribution. It shows that SiN/Ag/SiN coating with the thickness of 30/15/55 ... on the spectral selectivity, while the thicknesses of SiN layers affect diffraction position or intensity of the ... of the mutual diffusion between Ag film and SiN layers. The high visible transmittance and low infrared emittance of the SiN/Ag/SiN coating makes it a promising candidate ...

Tópico(s): Thin-Film Transistor Technologies

2022 - Elsevier BV | Infrared Physics & Technology

Artigo Acesso aberto

Danny Awty‐Carroll, Elena Magenau, Mohamad Al Hassan, Enrico Martani, Mislav Kontek, Philip van der Pluijm, Chris Ashman, Emmanuel de Maupeou, Jon McCalmont, Gert‐Jan Petrie, Chris Davey, Kasper van der Cruijsen, Vanja Jurišić, Stefano Amaducci, Isabelle Lamy, A. Shepherd, Jason Kam, Annick Hoogendam, Michele Croci, O. Dolstra, Andrea Ferrarini, Iris Lewandowski, Luisa M. Trindade, Andreas Kiesel, J. C. Brown,

... in 2018 with eight intraspecific M. sinensis hybrids ( sin × sin ) and six M. sacchariflorus × M. sinensis ( sac × sin ) from Dutch and UK breeding programmes, respectively, with clonal Miscanthus × giganteus. The planting density of the sin × sin was double that of sac × sin (30,000 & 15,000 plants ha −1 ), creating ... establishment depended on location and hybrid. The mature sin × sin hybrids formed tight tufts of shoots up to ... flower and senesce earlier than the taller sac × sin hybrids. Following the third growing season, the highest ...

Tópico(s): Agronomic Practices and Intercropping Systems

2022 - Wiley | GCB Bioenergy

Sermons Acesso aberto

Berdmore Compton,

Publisher's advertisement: p. [1] at end Book.

1877 - Gale Group | NCCO BritishPolitics

Artigo Revisado por pares

Yingkun Zhi, Jing Li, Lang Yi, Ruili Zhu, Jin-Fang Luo, Qing-ping Shi, Shasha Bai, Yanwu Li, Qun Du, Jiazhong Cai, Liang Liu, Peixun Wang, Hua Zhou, Yan Dong,

Sinomenine (SIN) is an anti-inflammatory drug that has been used for decades in China to treat arthritis. In a previous study, SIN acted on α7 nicotinic acetylcholine receptor (α7nAChR) to ... which indicates a new anti-inflammatory mechanism of SIN. However, the level of α7nAChR was increased in the inflammatory responses and was downregulated by SIN in vitro, so the underlying mechanisms of SIN acting on α7nAChR remain unclear.To analyze the ... in inflammation and the effect and mechanism of SIN regulation of α7nAChR.The effects of SIN on ...

Tópico(s): Receptor Mechanisms and Signaling

2022 - Elsevier BV | Phytomedicine