Fangli Ren, Fuqin Su, Hongxiu Ning, Yangmeng Wang, Yongtao Geng, Yarui Feng, Yinyin Wang, Yanquan Zhang, Zhe Jin, Yi Li, Baoqing Jia, Zhijie Chang,
... phosphorylation is negatively regulated. Here, we report that SIPAR (STAT3-Interacting Protein As a Repressor) inhibits STAT3 activity by accelerating its dephosphorylation. We observed that SIPAR directly interacted with STAT3 upon IL-6 stimulation. Moreover, over-expression of SIPAR reduced, whereas depletion enhanced, the level of phosphorylated STAT3. We further demonstrated that SIPAR inhibited the growth of melanoma cells by decreasing ... of its target genes. These results suggest that SIPAR, functioning as a new negative regulator, inhibits STAT3 ...
Tópico(s): interferon and immune responses
2013 - Elsevier BV | Cellular Signalling
Fangli Ren, Yongtao Geng, T. Minami, Ying Qiu, Yarui Feng, Chunxiao Liu, Juan Zhao, Yinyin Wang, Xuanzi Fan, Yangmeng Wang, Mengdi Li, Jun Li, Zhijie Chang,
... demonstrated that STAT3‐Interacting Protein As a Repressor (SIPAR) enhances the dephosphorylation of STAT3 and negatively regulates its activity. However, it remains unclear how SIPAR inhibits phosphorylation of STAT3. Here we demonstrate that SIPAR directly interacts with T cell protein tyrosine phosphatase ... triggers an accelerated dephosphorylation process for STAT3. Furthermore, SIPAR inhibits the transcriptional activity of STAT3 in wild‐ ... TC45 null MEF cells. These results suggest that SIPAR terminates the activation of STAT3 through a dephosphorylation ...
Tópico(s): Galectins and Cancer Biology
2015 - Wiley | FEBS Letters
Hadi Ramezani Etedali, Hamed Ebrahimian, Fariborz Abbasi, Abdolmajid Liaghat,
... in surface irrigation using mathematical models. The EVALUE, SIPAR_ID, and INFILT models were used in this ... the accuracy of the mathematical models. TheEVALUE and SIPAR_ID models provided the best performance, with EVALUE performing better than SIPAR_ID for estimating the Manning roughness coefficient. The ... irrigation than in standard irrigation. The performance of SIPAR_ID and INFILT in blocked-end and free ...
Tópico(s): Hydraulic flow and structures
1970 - Spanish National Research Council | Spanish Journal of Agricultural Research
Takao Hikita, Fatemeh Mirzapourshafiyi, Pedro Barbacena, Meghan Riddell, Ayesha Pasha, Mengnan Li, Takuji Kawamura, Ralf P. Brandes, Tomonori Hirose, Shigeo Ohno, Holger Gerhardt, Michiyuki Matsuda, Cláudio A. Franco, Masanori Nakayama,
... PAR-3 in HUVECs with two different siRNAs (siPAR-3#1 and #2) (Appendix Fig S3A), and ... transfected with control (Scrambled) or PARD3-specific siRNA (siPAR-3#1) and exposed to the indicated value ... treated with control (Scrambled) or PARD3-specific siRNAs (siPAR-3#1, B; or siPAR-3#2, C) in response to 12, 18, ...
Tópico(s): Angiogenesis and VEGF in Cancer
2018 - Springer Nature | EMBO Reports
J.A. Delgado RodrÍguez, J.C. Martos,
SIPAR_ID is a software based on a robust multiobjective inverse modeling technique for estimating field values ... a volume-balance model with artificial neural networks. SIPAR_ID also provides an estimate of the uncertainty ...
Tópico(s): Plant Water Relations and Carbon Dynamics
2008 - Elsevier BV | Environmental Modelling & Software
Wei‐Bo Nie, Liangjun Fei, Xiaoyi Ma,
... the infiltration parameters and Manning roughness estimated with SIPAR_ID software, and to analyze the impacts of ... Infiltration parameters and Manning roughness were estimated with SIPAR_ID software. The estimated values were input into ... the infiltration parameters and Manning roughness estimated with SIPAR_ID software were reliable. It was found that ...
Tópico(s): Hydraulic flow and structures
2014 - Spanish National Research Council | Spanish Journal of Agricultural Research
Shun Hu, Liangsheng Shi, Yuanyuan Zha, Kai Huang,
... sugarcane ( Saccharum officinarum L.) yield model, called the SiPAR model (intercepted photosynthetically active radiation partitioned to stem), ... the process‐based models and strong robustness. The SiPAR model was developed using the normalized difference vegetation ... experiment was used to evaluate model performance. The SiPAR model was also compared with three traditional statistical models. The results showed that (a) the SiPAR model obtained the highest accuracy among the compared ... Ry) = 7.22–11.77%) and (b) the SiPAR model had better spatial and temporal stability than ...
Tópico(s): Plant Water Relations and Carbon Dynamics
2021 - Wiley | Agronomy Journal
... article propose l'analyse d'un objet technique, SIPAR, comme contribution à une réflexion sur les innovations ... A partir d'une observation des usages de SIPAR, l'article examine comment les travailleurs sociaux composent ...
Tópico(s): Aging, Elder Care, and Social Issues
2008 - UMR ESPACE et UMR LISST | Champ pénal
Aurélie Giraud, Socheata Huot,
Promoting Literacy in Southeast Asia: SIPAR Helps Cambodian Children Discover the Joys of Reading Aurélie Giraud (bio) and Socheata Huot (bio) Click for larger view View full ... la Reconstruction des pays du sud-est asiatique (SIPAR) is dedicated to providing children with access to books and reading programs throughout Cambodia. SIPAR has been working to promote literacy in Cambodia ... Cambodia’s rehabilitation and development process in 1991, SIPAR contributed to educational advancement by prioritizing literacy and ...
Tópico(s): Cambodian History and Society
2012 - Johns Hopkins University Press | Bookbird/Book bird
Wei‐Bo Nie, Yibo Li, Fan Zhang, Shu-Xin Dong, Heng Wang, Xiaoyi Ma,
... and Manning’s roughness, which were inversed by SIPAR_ID. The results indicated that the inflow discharge ...
Tópico(s): Soil and Unsaturated Flow
2018 - Multidisciplinary Digital Publishing Institute | Water
Xi Huang, Zhenxiong Ye, Lifeng Chen, Xujie Chen, Caocong Liu, Yuan Yin, Xinpeng Wang, Yuezhou Wei,
... this study, a silica-supported primary amine resin (SiPAR) was prepared by in-situ polymerization, and the ...
Tópico(s): Metal Extraction and Bioleaching
2020 - Multidisciplinary Digital Publishing Institute | Molecules
Produção Nacional
Revisado por pares
Guilherme Navarro Nilo Giusti, Patrícia Yoshioka Jotta, Caroline de Oliveira Lopes, Mônica Aparecida Ganazza, Amilcar Cardoso de Azevedo, Sílvia Regina Brandalise, João Meidânis, José Andres Yunes,
... PRONON (Programa Nacional de Apoio à Atenção Oncológica, SIPAR 25000.057709/2015) together with Tetra Park Ltda, ...
Tópico(s): Cancer Genomics and Diagnostics
2020 - Wiley | British Journal of Haematology
Seyed Mahmoud Tabatabaei, Rasoul Asadi,
... infiltration parameters based on mathematical models such as SIPAR_ID model. SIPAR_ID model uses inverse solution to estimation of ... parameters and Manning roughness values were estimated with SIPAR_ID software. The estimated values were put into ... the infiltration parameters and manning roughness estimated with SIPAR_ID software were reliable. Also that adequate and ...
Tópico(s): Soil and Unsaturated Flow
2015 - Progressive Sustainable Developers Nepal | International Journal of Life Sciences
Shun Hu, Liangsheng Shi, Yuanyuan Zha, Linglin Zeng,
... models (i.e., the CNDVI, K–M, and SiPAR models) were applied to predict yield in America, ... America were used. The results showed that the SiPAR model outperformed the CDNVI and K–M models ... directions. This study demonstrated the robustness of the SiPAR model and investigated the sugarcane yield status in ...
Tópico(s): Irrigation Practices and Water Management
2022 - Multidisciplinary Digital Publishing Institute | Remote Sensing
Ning Hongxiu, Rong Yu, Yuanjiang Zhang, Fangli Ren, Chang Zhijie,
Tópico(s): NF-κB Signaling Pathways
2005 - Science Press | PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
... justice, nous montrons comment une application informatique, dénommée SIPAR, participe à la reconfiguration du travail social en ...
Tópico(s): Education, sociology, and vocational training
2013 - Medecine et hygiene | Déviance et Société
... des élèves instituteurs au Cambodge par l'ONG Sipar (Soutien à l'initiative privée pour l'aide ... des besoins. On peut considérer que l'ONG Sipar joue un rôle clé dans l'évolution des ...
Tópico(s): African Studies and Ethnography
2011 - France Education International | Revue internationale d éducation de Sèvres
Reedwan Bin Zafar Auniq, Md. Nazim Uddin Chy, Md. Adnan, Md. Riad Chowdhury, Trishala Dutta, Sadab Sipar Ibban, Israt Jahan, Marzia Rahman Tona, Mutakabrun Shima, Md. Imtiajul Habib Sawon, Nishan Chakrabarty, Shakawat Hossain, Arkajyoti Paul,
Tópico(s): Natural Antidiabetic Agents Studies
2020 - Springer Nature | Advances in Traditional Medicine
... a novel protein with 259 amino acids, named SIPAR (STAT3 interacting protein as a repressor) with a ... interact with STAT3. The interaction between STAT3 and SIPAR was analyzed using yeast two hybrid experiments and ... lift filter assay and liquid assay showed that SIPAR had a strong interaction with STAT3. The Western blot experiment showed SIPAR was expressed as a 28 ku protein and ... cells. In order to investigate the function of SIPAR on STAT3 signal pathway, STAT3 luciferase reporter system and SIPAR expression plasmids were co-transfected into mammalian cells. ...
Tópico(s): RNA modifications and cancer
2005 - Science Press | PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
Tópico(s): French Urban and Social Studies
2015 - | La Revue Nouvelle
... orðinum fyri »havhest « (»náta«); ætlað verður, at tað sipar til, at hesin fuglur spýr frá sær, og ... liður í lundanevninum karkarassur (viðhvørt karkarakkw ella karkareyði) sipar til ljóðið, ið lundin gevur frá sær. Orðið ...
Tópico(s): Ecology and biodiversity studies
1971 - | Fróðskaparrit - Faroese Scientific Journal
Surface irrigation parameters identification(SIPAR-ID) model was employed to estimate the infiltration parameters and Manning roughness according to the water advance trajectory of furrow ... These indicated that it is reliable to use SIPAR-ID model to estimate the infiltration parameters and ...
Tópico(s): Hydraulic flow and structures
2012 - Editorial Department of Agricultural Research in the Arid Areas | Ganhan diqu nongye yanjiu
J. Sanchez-Jaramillo, Gilberto Espinosa-Paredes, Jaime B. Morales-Sandoval,
... autocatalytic recombiner, which is called, in this work, SIPAR. The driven flow of the steam injector is ... at low pressure. Preliminary results show that the SIPAR can be installed into reactor containment for the ...
Tópico(s): Nuclear reactor physics and engineering
2014 - Taylor & Francis | Energy Sources Part A Recovery Utilization and Environmental Effects
... enda merkir blikur bókstavliga 'glampi, ljómi, glitur' og sipar til hin glæsiliga fjaðurhamin.
Tópico(s): Lepidoptera: Biology and Taxonomy
1971 - | Fróðskaparrit - Faroese Scientific Journal
... hava merkt 'sangari'. Svala merkir upprunaliga 'kvísl', ið sipar til kloyvda ella sýlda velið. Svanur merkir bókstavliga ' ...
Tópico(s): Bryophyte Studies and Records
1982 - | Fróðskaparrit - Faroese Scientific Journal
Gunni Jørgensen, Jóannes Rasmussen,
... í greinini settar upp í røð, talmerktar, talið sipar til hjálagt kort, og sundurbýttar í bólkar sum ...
Tópico(s): Polar Research and Ecology
1981 - | Fróðskaparrit - Faroese Scientific Journal
... winners: Abuelas Cuentacuentos—The Grandmothers Storytelling Programme, and SIPAR—Soutien à Initiative Privée pour l’Aide à ...
Tópico(s): Themes in Literature Analysis
2012 - Johns Hopkins University Press | Bookbird/Book bird
Produção Nacional
Luís Gustavo Abdalla, Karina Andrighetti de Oliveira Braga, Lucas Matos Fernandes, Marcos Naoyuki Samano, Paula Refinetti Camerini, Paulo Manuel Pêgo‐Fernandes, Samano Mn,
... of Health through the PROADIS-SUS Program (Process/SIPAR Nº 25000.014875/2015-12 part of the ...
Tópico(s): Organ Donation and Transplantation
2019 - Instituto Israelita de Ensino e Pesquisa Albert Einstein | Einstein (São Paulo)
... tolkast á tvinnanda hátt: Í nógv flestum førum sipar tað til dýraheitið selur k. ‘kópur/kobbi’, men ...
Tópico(s): Lexicography and Language Studies
2024 - | Fróðskaparrit - Faroese Scientific Journal
Shafiul Azam Zishan, Md. Maien Uddin, Mahathir Mohammad, S.M. Asadul Karim Azad, Jannatul Naima, Sadab Sipar Ibban, Md. Saiful Islam Arman,
Abstract Background The present study investigated the potential wound healing activity comparisons between ethanol leaf & seed extracts of Costus speciosus topical formulation using mice Excision wound models, compared to Neomycin sulphate ointment as a standard drug. To assess the efficacy of Costus speciosus ointment as a potential alternative to commercially available ointments, a study was conducted using a cohort of 16 healthy male mice, aged between 3 and 4 months. The ointment formulation ...
Tópico(s): Phytochemistry Medicinal Plant Applications
2024 - Springer Nature | Clinical Phytoscience