Produção Nacional
Maria de Lourdes L. F. Chauffaille, Sofia M. M. Sugayama, Durval Damiani, José Gilberto H. Vieira, Vânia Hungria,
Tópico(s): Chronic Lymphocytic Leukemia Research
2007 - Elsevier BV | Cancer Genetics and Cytogenetics
Produção Nacional
Revisado por pares
Jesús F. San Miguel, Vânia Hungria, Sung‐Soo Yoon, Meral Beksaç, Meletios Α. Dimopoulos, Ashraf Elghandour, W Wiktor-Jędrzejczak, Andreas Guenther, Thanyaphong Na Nakorn, Noppadol Siritanaratkul, Robert Schlossman, Jian Hou, Philippe Moreau, Sagar Lonial, Jae Hoon Lee, Hermann Einsele, Hans Salwender, Monika Sopala, Suman Redhu, Sofia Paul, Claudia Corrado, Paul G. Richardson,
Summary Panobinostat in combination with bortezomib and dexamethasone demonstrated a significant and clinically meaningful progression‐free survival benefit compared with placebo, bortezomib and dexamethasone in the phase 3 PANORAMA 1 (Panobinostat Oral in Multiple Myeloma 1) trial. Despite this benefit, patients in the panobinostat arm experienced higher rates of adverse events ( AE s) and higher rates of discontinuation due to AE s. This PANORAMA 1 subanalysis examined AE s between 2 treatment phases ...
Tópico(s): Protein Degradation and Inhibitors
2017 - Wiley | British Journal of Haematology
R. Segura-Saint-Gerons, Carmen Segura-Saintgerons, R. Alcantara-Luque, JM. Arizon-del Prado, C. Foronda-Garcia-Hidalgo, A. Blanco-Hungría,
... on in the Heart Transplantation Unit of Reina Sofía University Hospital (Spain), using the OHIP-49 questionnaire. ...
Tópico(s): HIV/AIDS oral health manifestations
2011 - Medicina Oral S.L. | Medicina oral, patología oral y cirugía bucal
Produção Nacional
Revisado por pares
Jesús F. San Miguel, Vânia TM Hungria, Sung‐Soo Yoon, Meral Beksaç, Meletios Α. Dimopoulos, Ashraf Elghandour, W Wiktor-Jędrzejczak, Andreas Guenther, Thanyaphong Na Nakorn, Noppadol Siritanaratkul, Robert Schlossman, Jian Hou, Philippe Moreau, Sagar Lonial, Jae‐Hoon Lee, Hermann Einsele, Hans Salwender, Monika Sopala, Suman Redhu, Sofia Paul, Claudia Corrado, Florence Binlich, Paul G. Richardson,
Abstract Introduction: Panobinostat (PAN) is a potent pan-deacetylase inhibitor (pan-DACi) that targets key aberrations in multiple myeloma (MM) cell biology, including protein metabolism and epigenetics. In a randomized phase 3 clinical trial in patients (pts) with relapsed or relapsed and refractory MM (PANORAMA 1), the addition of PAN to bortezomib (BTZ) and dexamethasone (Dex; PAN-BTZ-Dex) led to a clinically relevant and statistically significant increase in progression-free survival (PFS) of ≈ 4 months ...
Tópico(s): Protein Degradation and Inhibitors
2014 - Elsevier BV | Blood
Rafael Segura Saint Gerons, Carmen Segura Saint Gerons, Rosario Alcántara Luque, José María Arizón del Prado, Carla Foronada García Hidalgo, Antonio Blanco Hungría,
... consulta de trasplante Cardiaco del H.U. Reina Sofia, a traves de esta encuesta. Los pacientes que ...
Tópico(s): Transplantation: Methods and Outcomes
2012 - Medicina Oral S.L. | Medicina oral, patología oral y cirugía bucal