Rachid El Fatimy, Sandra Tremblay, Alain Y. Dury, Samuel G. Solomon, Paul De Koninck, John W. Schrader, Édouard W. Khandjian,
Fragile X syndrome is caused by the absence of the Fragile X Mental Retardation Protein (FMRP), an RNA-binding protein. FMRP is associated with messenger RiboNucleoParticles (mRNPs) present in polyribosomes and its absence in neurons leads to alteration in synaptic plasticity as a result of translation regulation defects. The molecular mechanisms by which FMRP plays a role in translation regulation remain elusive. Using immunoprecipitation approaches with monoclonal Ab7G1-1 and a new generation of ...
Tópico(s): RNA Research and Splicing
2012 - Public Library of Science | PLoS ONE
Rachid El Fatimy, Sandra Tremblay, Alain Y. Dury, Samuel G. Solomon, Paul De Koninck, John W. Schrader, Édouard W. Khandjian,
Fragile X syndrome is caused by the absence of the Fragile X Mental Retardation Protein (FMRP), an RNA-binding protein.FMRP is associated with messenger RiboNucleoParticles (mRNPs) present in polyribosomes and its absence in neurons leads to alteration in synaptic plasticity as a result of translation regulation defects.The molecular mechanisms by which FMRP plays a role in translation regulation remain elusive.Using immunoprecipitation approaches with monoclonal Ab7G1-1 and a new generation of chicken ...
Tópico(s): Genetics and Neurodevelopmental Disorders
2012 - Public Library of Science | PLoS ONE
... Philosophies of Mind and Nature") and Thomas de Koninck ("Persons and Things") each give a defense ofthe ... cannot admit the reality of such states. De Koninck, likewise, shows (contra Michael Tooley) that human life ... from conception until death. Both Haldane and de Koninck stress the need of correctly understanding the formal ... also deals with ethics. Alasdair Macintyre and David Solomon bring out the same point, but in complementaryways. ...
Tópico(s): Religion, Ecology, and Ethics
2002 - Pontifical Faculty of the Immaculate Conception | The Thomist