Susan D'arcy, Michael Prescott, Julia Pascal, Barbara Hall, Annie Chaplin, Toby Young, Tony Birtley, Paul Nelson, Richard Ellis, Seosamh O Murchú, John Davison, Peter Frank, Helen Davidson, Debbie Moore, diana Wright, John Peter, Mark Reason, John Harlow Transport Correspondent, Jonathan Miller, Eric Dymock, Norman MacRae, Lesley White, Dr Mary Henry, Bill Gates, Tony Francis, Susan d'Arcy, John Akers, John Diamond, Graham Rose, Diana Wright Personal Finance Editor, Alistair Scott, Sally Payne, David Smith, Nicholas Hinton Director-general, Adam Nicolson, Nick Pitt, Taylor, Frederic Raphael, Charles Hymas, Edward Welsh, Richard Guilliatt, Caroline Lees Arts Correspondent, Tony Allen-Mills, Martin James, Robert Sandall, Joanne Harris, Benedic Hayhoe, Ivan Allen Exhibition Director, Iain Johnstone, Nilgin Yusuf, Irwin Stelzer, Ivan Fallon, Deryk Brown, Isabel Wolff, David Dougill, Cliff Temple, Ally McCoist, Ingrid Millar, Harvey Porlock, Hugh Canning, Margarette Driscoll, Peter Kemp, Sean Ryan, Geoff Whitten, Peter Millar, Caroline Lees, Ismail Merchant, Peter Kellner, Richard Dawood, George Perry, John Cassidy, Kristle Hamilton, Mark Skipworth, Anatole Kaletsky, Nick Gardner, Lynne Routledge, Stewart Roberts, Jonathan Margolis, Christine Toomey, Richard Lloyd Parry, Bernard Cafferty, David Bowie, Stuart Wavell, Roger Eglin, Paul Donovan, Paul Eastman, Christopher Llyod, Jeff Randall, Shelley von Strunkel, James Bethell, R Nicholson-Morton, James Adams, Paul Driver, Margaret Dibben, Charlie Bubbles, Nicholas Fraser, Tim Rayment, Peter Plant, Kirstie Hamilton, Rufus Olins, David Lawrenson, Brian Sewell, Martin Jacques, Nicola Lang, Dave Thomas, Christopher Lloyd, Derek Hudson, Helen Fielding, kristie Hamilton, Lois Rogers, Margaret Campbell, John Karter, Jack Aspinall, Malcolm Winton, Peter Hall, Greg Hadfield, Diana Wright, Craig Brown, Stephen Jones, Imogen Edwards-Jones, Andrew Grice Chief Political Correspondent, Quentin Crisp, Andrew Grice, Irwin Steizer, Julie Cohen, Keith Wheatley, Annie Murphy, Ian Birrell, Anthony Quinn, Marcel Berlins, Safa Haeri, Lois Rogers Medical Correspondent, Chris Jones, Andrew Hogg, Bruce Johnston, R Scheer, T Rac Smith, Richard Woods, Garth Alexander, Paul Kennedy, Peter Johnson, David Churchill, Alan Dershowitz, Maurice Chittenden, Sarah-Rhiannon Barber, N E Gayle, Dr Richard Sakwa, David Oates, Kristie Hamilton, Dai Jeffries, Julie Burchill, David, Michael Jones Political Editor, Roger Clarke, Rebecca Fowler, Nicholas Archer, David Hunn, John Bowman, Berry Tomalin Head of Marketing, D J Taylor, Mihir Bose, John Harlow, Matthew Lynn, Michael Austin, Hugh Fearnley-Whittingstall, Andrew Alderson, Alastair Burnet, Matthew Campbell, Stan Levenson, John Carey, Brian Innes, Christopher Summerfield, Chrissy Iley, Robert Leyshon, Lauren St John, Tom Tickell, Gilbert Adair, John Furbisher, Liam Clarke, David Wickers, Alan Ruddock, Goliath, Victor Bryant, Chris Lightbown, Mia Farrow, Nigel Roebuck, Jeff Randall City Editor, Hugh Pearman, David Smith Economics Editor, Penny Perrick, Tony Hetherington, Walter Ellis, Joanna Simon, kirstie Hamilton, Iain Jenkins, Janine di Giovanni, Boris Schapiro,
... sales by their former hero, asks Alan Ruddock Sonic the Hedgehog Stogecoach Holdings plc Swansea Centre for Trade & Industry Mario and Sonic fight the PC pirates Top computer-game makers stand to ...
1993 - Gale Group | Sunday Times HA GDA
Lisa V. Goodrich, Matthew P. Scott,
... L. Tabin C.J. Conservation in hedgehog signaling Sonic hedgehog controls the expression of a chicken patched homolog in the ... L. Tabin C.J. Conservation in hedgehog signaling Sonic hedgehog controls the expression of a chicken patched homolog in the ... D. Johnson R.L. Laufer E. Tabin C. Sonic hedgehog mediates the polarizing activity of the ZPA.Cell. 1993; 75: ... L. Tabin C.J. Conservation in hedgehog signaling Sonic hedgehog controls the expression of a chicken patched homolog in the ... Bumcrot D.A. Mahanthappa N.K. Pang K. Sonic hedgehog promotes the survival of specific CNS neuron populations and protects ...
Tópico(s): Congenital Ear and Nasal Anomalies
1998 - Cell Press | Neuron
George Cole, Stephen Woodard, Director, Anthony Harris, Jon Ashworth, Nick Nuttall, Andrew Pierce, Chris Ward, Grace Bradberry, Robin Dartington, Director, Richard Ford, Home Correspondent, Bill Frost, George Ball, Andrew Longmore, Catherine Field, Harvey Elliott, Philip Howard, Dorothy Sullivan, Jeremy Kingston, Rachel Campbell-Johnston, Sheila Johnston, Agence France-Presse and Christopher Thomas, Carl Mortished, Morag Preston, Gillian Maxey, Kevin Eason, James Bone and our Foreign Staff, Robert Sheehan, Bridge Correspondent, Robert Miller, Kate Alderson and Joanna Bale, Guy Clapperton, Raymond Keene Chess Correspondent, Rachel Kelly, Audrey Magee Ireland Correspondent, Harry Brampton, Charles Bremner and Michael Hornsby, Mike Rosewell Rowing Correspondent, Rodney Milnes, Jenny MacArthur, Francesco Bongarra, Michael Clark, Jeremy Laurance, Health Correspondent, Quentin Letts, Sam Kiley, Africa Correspondent, and James Bone, Joseph Connolly, John Kavanagh, Jill Sherman and Andrew Pierce, Philip Bassett, Industrial Editor, G. M. Covey, Luke Clancy, Ian Murray Community Correspondent, Brenda Maddox, Leyla Linton and our Foreign Staff, Belinda Archer, John Hopkins, David Miller, Alan Toogood, Horticulture Correspondent, Dalya Alberge, Arts Correspondent, Michael Prestage, Michael Hornsby, Agriculture Correspondent, and Diana Thorp, Hubert Chesshyre, Raymond Keene, Christine Buckley, Valerie Howarth, Chief Executive, Emma Wilkins and Simon De Bruxelles, Alix Ramsay, P. H. S, Chris Partridge, James Morgan, Eric Reguly, John Carr, Sarah Cunningham, Malcolm Windsor, Secretary, Nick Kelly, Denis O'brien, Dalya Alberge, Alison Beckett, Julian Muscat, Adam Fresco, Jill Sherman and Philip Webster, Christopher Thomas, John Goodbody, Dominic Kennedy, Iola Smith, Nick Nuttall, Technology Correspondent, Sara McConnell, Christopher Walker, James Pringle, Chris Parker, Brian MacArthur, Jason Nissé, Craig Lord, Anjana Ahuja, Michael Hornsby, Peter Riddell, Ben MacIntyre, Ray Hatley, Atlanta sketch, Ian Brodie, Alan Lee Cricket Correspondent, Tony Dawe, Frances Lass, David Sinclair, Simon Jenkins, Fraser Nelson, Tim Jones, Simon Armson, Chief Executive, Alan Coren, Christopher Warman, Benedict Nightingale, Nigel Powell, Tom Rhodes, Frances Gibb Legal Correspondent, Lindsay Nicolle, Michael Evans Defence Correspondent, Morag Prestion, Richard Morrison, Gordon Brown, Branson claims, David Maddock, Alice Thomson, Political Reporter, Alasdair Murray, Collin Cowe, George Racz, Nicholas Temperley, Matthew Bond, Tunku Varadarajan and our Foreign Staff, Amandip Upal, Edward Gorman Sailing Correspondent, Richard Ford, Kevin Eason, Motoring Editor, Olympic diary, Stacy Sullivan, George Guise, Stephen Cox Campaigns manager,
... on a system that gives extra spikes to Sonic the Hedgehog Full control of an emergency A US system ...
1996 - Gale Group | TDA
... J. Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons.J Neurosci. ... J. Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons.J Neurosci. ... J. Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons.J Neurosci. ... J. Interactions of Wnt/beta-catenin signaling and sonic hedgehog regulate the neurogenesis of ventral midbrain dopamine neurons.J Neurosci. ...
Tópico(s): Neurogenesis and neuroplasticity mechanisms
2015 - Elsevier BV | American Journal Of Pathology
Andrew Robson, Ian Raath, Michael Dynes and Daniel McGrory, Raymond Snoddy Media Editor, Andrew Pierce, James Moore, Patricia Davies, Grace Bradberry, Nicholas Serota, Director, Sarah Potter, Simon Barnes, Paul Hoggart, Claire McDonald, Richard Hobson, Martin Richards, David Rhys Jones, Ivo Tennant, Jonathan Lennie, Michael Evans Defence Editor, Philip Howard, Anders Panum Jensen Secretary General, Alexandra Frean Social Affairs Correspondent, Elizabeth Judge, Lynne Truss, Ernest Spacey, Morag Preston, Barbara Hewson, Kevin Eason, Geoff Brown, Joe Joseph, Andrew Norfolk, John O'Leary Education Editor, Laura Campbell, Conal Urquhart, David McVay, Pat Gibson, Tom O'Sullivan, Paul Baskerville (President), Gary Jacob, Hugh Leggatt, Alix Ramsay Tennis Correspondent, Kevin Eason Motor Racing Correspondent, Dalya Alberge Arts Correspondent, Edward Bridger-Stille, Michael Mulvihill, Mark Inglefield, Bernard Connolly, Mike Rosewell Rowing Correspondent, Stephen Farrell, John O'Leary, Helen Rumbelow Medical Reporter, Frances Lowe, David Hands, Charles Bremner, Kate Kirwan, Peter Barnard, Roger Maynard and Tim Reid, James Doran City Correspondent, Daniel McGrory, Paul Armstrong, Aileen Moss, Julian K-C Ma, Paul McCann, Bernard J. Mulholland, Lisa Armstrong, Tom Baldwin, Matt Dickinson Football Correspondent, Anna Söderblom, David Lawrenson, Christopher Martin-Jenkins, John Hopkins Golf Correspondent, Geoffrey Dean, Alec McGivan, Celia Brayfield, Stuart Miles, David Powell Athletics Correspondent, Raymond Keene, Adam Sage, David Robinson, Clive Mathieson, Sue Unwin, Matt Dickinson, Alix Ramsay, Christine Buckley Industrial Editor, Peter Bryan, Tony Swann, Chris Ayres Media Business Correspondent, Richard Owen, Roger Bootle Economic, Christopher Martin-Jenkins Chief Cricket Correspondent, Mick Hume, Barry Oakley, Roger Boyes, Anne Ashcroft, David Hands Rugby Correspondent, Julian Muscat, Ben Hammersley, John Allison, William Rees-Mogg, John Goodbody, Nick Szczepanik, James Doran, Alan Copps, Krishna Sethia, Mel Webb, Michael Fitzpatrick, Srikumar Sen Boxing Correspondent, Kevin McCarra, Graham Searjeant Financial Editor, Sean Hargrave, George Caulkin, Chris McGrath, Sam Westmacott, Tim Wapshott, Moira Petty, Caitlin Moran, Michael Austin, Alan Lee, Keith Blackmore, Adam Sage and Andrew Norfolk, Ben MacIntyre, Peter Riddell, Tony Dawe, Michael Dynes, Deryke Belshaw, Lea Paterson, Fran Littlewood, Roy Jenkins, Lindsay Nicolle, Tom Baldwin Deputy Political Editor, Robert Whymant, Sally Patten, Lea Paterson Economics Correspondent, David Wright, Fraser Nelson Retail Correspondent, Don Paterson and Jo Shapcott, Dr Keyboard, Christopher Irvine, Joanna Coles, John Watson, Arthur Leathley Transport Correspondent,
... Tournament puts new slant on TV game show Sonic the Hedgehog's on the phone for you My kind ...
2000 - Gale Group | TDA
Carol A. Podlasek, Cynthia L. Meroz, Helen L. Korolis, Yi Tang, Kevin E. McKenna, K. McVary,
... in order to maintain homeostasis in the adult. The morphogen, Sonic hedgehog (Shh), is a crucial regulator of these processes, along with its down stream targets patched (Ptc), Hox, bone morphogenetic proteins (BMP's), vascular endothelial growth factor (VEGF) and nitric oxide synthase (NOS). Shh is critical for patterning and establishing tissue identity of the penis during embryonic development, is a crucial regulator ...
Tópico(s): Sexual function and dysfunction studies
2005 - Bentham Science Publishers | Current Pharmaceutical Design
Alan Hone, J.P. Lee-Potter, Paul Steinmetz, Philip Kossoff, Charles Stuart, Ruth Elliott,
... grow D-marks PC plodder NEC Poached by Sonic the Hedgehog Propinquity pays Bavaria and Bohemia Lonrho When sparks ...
1993 - Gale Group | The Economist
Manuel Hitzenberger, Daniela Schuster, Thomas S. Hofer,
... of complex formation between the extracellular signaling protein Sonic Hedgehog and the transmembrane protein Patched 1. In 2009 robotnikinin, a ... order to aid with the identification of novel Sonic Hedgehog inhibitors, the presented investigation elucidates the binding mode of robotnikinin ... binding of the ligand. The predicted structure of the Sonic Hedgehog-robotnikinin complex is provided via a PDB file ...
Tópico(s): Oral and Maxillofacial Pathology
2017 - Frontiers Media | Frontiers in Chemistry
Arthur Leathley, Transport Correspondent, Martin Fletcher and Peter Riddell, Jon Ashworth, Noreen Taylor, Joanna Hunter, Nick Nuttall Environment Correspondent, Robert Cole, Business Editor Patience Wheatcroft, Patricia Davies, Zahid Hussain, Adrian Lee, Grace Bradberry, Nick Makin, Simon Barnes, Jasper Rees, Frances Gibb and Roland Watson, G. Pocock, Christopher Walker, Chief Ireland Correspondent, Raymond Snoddy, Media Editor, Jane Bolton, Philip Howard, Hilary Finch, Caroline Merrell, Banking Correspondent, James Bone, Roland Watson and Paul Durman, David Robinson and Perry Cleveland-Peck, Christine Buckley Industrial Correspondent, Robert Sheehan, Bridge Correspondent, Joe Joseph, David McVay, Richard Duce and Russell Jenkins, Donald Hutera, Stewart Tendler Crime Correspondent, Martin Stephen, Dominic Walsh, George Thomas, Alasdair Reid, Raymond Keene Chess Correspondent, Robin P. Cole, Michael Harvey, Melvin J. Lasky Editor, David Orr and Michael Evans, Richard Ford Home Correspondent, Alan Hamilton, Mark Inglefield, Andre Menache Prisident, John O'Leary, Ian Hughes, Keith Pike, W. D. O'brien, David Hands, Charles Bremner, John Kavanagh, Jane Napolitano, Catherine Lockwood, Peter Barnard, Michael Binyon Diplomatic Editor, Derwent May, Jilly Cooper, Paula Hawkins, Paul Armstrong, Richard Cork, John Bercow, Paul Durman, Ken Livingstone, H. McG. Dunnett, John Hopkins, Karen Homer, Laurence McTaggart, Rob Wright, Stephen Wood, Dalya Alberge, Arts Correspondent, Adam Jones, Marcus Binney, Raymond Keene, Clive Mathieson, John Russell Taylor, Matt Dickinson, Tom Baldwin, Deputy Political Editor, Paul Wilkinson, David Orr, Nigel Hawkes, Ashley Grossman, Carl Mortished, International Business Editor, Tony Patrick and Louise Godfrey, Gavin Lumsden, Insurance Correspondent, Roger Boyes, Nick Hasell, Philip Webster, Political Editor, Robert Cole, City Correspondent, Oliver Holt, Football Correspondent, David Hands Rugby Correspondent, Anne Ashworth, Giles Whittell, Saeed Shah, Mel Webb, Kevin McCarra, Anjana Ahuja, Kyran Bracken, George Caulkin, Melissa Kite Political Reporter, Aubrey Bristow, Victoria Greenhalgh, Peter Gaupp, Ben MacIntyre, Roy Hattersley, Jeremy Hart, Michael Dynes, David Sinclair, Simon Jenkins, Simon Mathews, Tim Jones, Lea Paterson, Mark Henderson, Martin Waller, Chris Ayres, Alan Coren, Mark Baldwin, Daniel Rosenthal, Alan Copps Interface Editor, Benedict Nightingale, Richard Morrison, Alyson Rudd, Sam Kiley, Alice Miles, Arthur Leathley, Valerie Grove, Harriet Harman, Tom Baldwin Deputy Political Editor, Michael Evans, Alan Lee Racing Correspondent, Sally Patten, Anthony Howard, David L. Crosby, Chairman, Christopher Irvine, Susan Emmett,
... Bank of Scotland JUG club beats FTSE Vodafone The 'sonic hedgehog' gene that could cure baldness Scientists have managed to kick-start hair growth using a genetic therapy that switches on dormant follicles. Anjana Ahuja reports The Times Heart disease twist When crisps are good ...
1999 - Gale Group | TDA
Takaaki Furumoto, Naoyuki Miura, Takeshi Akasaka, Yoko Mizutani-Koseki, Hidefumi Sudo, Katsuyuki Fukuda, Mamiko Maekawa, Shigeki Yuasa, Yan Fu, Hideshige Moriya, Masaru Taniguchi, Kenji Imai, Edger Dahl, Rudi Balling, Maria N. Pavlova, Achim Gossler, Haruhiko Koseki,
... are mainly mediated by the diffusible signaling molecule Sonic hedgehog. The products of the paired-box-containingPax1and the mesenchyme ... column. Here, we demonstrate thatMfh1likePax1expression is dependent on Sonic hedgehog signals from the notochord, andMfh1andPax1act synergistically to generate the vertebral column. ... Pax1double mutants strongly correlate with the reduction of the mitotic rate of sclerotome cells. Thus, both theMfh1and thePax1gene products cooperate to mediate Sonic hedgehog-dependent proliferation of sclerotome cells.
Tópico(s): Genomic variations and chromosomal abnormalities
1999 - Elsevier BV | Developmental Biology
Michael Prescott, Victoria McKee, William Kay, J Hirschkorn, Carol Berger, Paul Nelson, Richard Ellis, James Dairymple, Thomas Hinde, William Chidgey, Jon Swain, Rob Hughes, John Peter, Mark Reason, Dalian Atkinson, John Harlow Transport Correspondent, Jonathan Miller, Bill Gates, Tony Francis, Susan d'Arcy, Nick Rufford, John Diamond, Frank Whitford, Graham Rose, John Stansell, Colln Dryden, Sheridan Morley, Brlan Reading, Christa D'souza, Euenne De Nil General Manager, Kirstle Hamilton, Alistair Scott, Sally Payne, David Smith, Simon Mackenzie, Nick Pitt, Gillian Hall, Charles Hymas, Karen Wright, Liz Hodgkinson, Gerald Ratner, Judith Massey, Geordie Greig, Martin James, Iain Johnstone, Keith Austin, Robert Hewison, Cyril Dixon, Ivan Fallon, Gerald Matthews, David Dougill, Tim Wright, Steve Broadhead, Edwards Welsh, Hugh Canning, Maurice Jay, Michel Montignac, Caroline Lees, George Perry, Sue Mott, Christine Toomey, Bernard Cafferty, Brian Moynahan, Simon Banner, Stuart Wavell, John David, Paul Donovan, Peter Hounam, T Gorsuch, Major Thoburn, Mandy Smith, Simon Mills, Jeff Randall, Paul Driver, James Adams, Paul Bray, Chris Long, Margaret Dibben, Steven Downes, Shelley Von Strunckel, Matthew Gwyther, Tyler Brule, David Leppard, Tim Rayment, Peter Plant, Andrew Gibbon Williams, Richard Girling, Mark Edwards, Tom Shone, Rufus Olins, Mary Anne, David Lawrenson, Martin Jacques, Nick Raynsford Mp, Nicola Davidson, Robert Lacey, Charles Hymas Education Correspondent, Christopher Lloyd, Philip Ross, J Bateman, John Karter, Kate Saunders, Barbara Amiel, Malcolm Winton, Wendy Wilson, Craig Brown, Kipper Williams, Loyd Grossman, Stephen Jones, Carnie, Harry Mullan, Nick Hornby, Tony Allen Mills, Andrew Grice, Tony Osborne, Dominic O'Brien, Martin Searby, Karl Dallas, Marmaduke Hussey, David Mellor, Gabriel Ronay, Dilys Powell, Andrew Lorenz Associate Business Editor, Bernard Fitzsimons, Richard Woods, Clive Everton, Garth Alexander, Norman Stone, Peter Johnson, Sir Christopher Hogg, David Churchill, Mitchell Symons, Michael Jones Political Editor, Andrew Yates, David Hunn, Peter Bennett, Tim Carrigan, Mihir Bose, Philip Beresford, Godfrey Smith, Caitlin Moran, Andrew Alderson, Angus Shearer, Dean Saunders, Ed McHenry, R Keevil, Matthew Campbell, Stan Levenson, Norman Macrae, Chris Dighton, Chris Bidmead, Anthony Holden, Godfrey Golzen, Chrissy Iley, Gilbert Adair, Andrew Lorenz, Liam Clarke, Faci Stephen, Alan Ruddock, Elizabeth Thomas, David Richardson, Chris Lightbown, Vince Wright, Jeff Randall City Editor, Hugh Pearman, John Burns, Alan Sugar, David Smith Economics Editor, Tony Hetherington, Jon Stock, Julia Bright, Peter Roebuck, Bill Wyman, Joanna Simon, Meryl Streep, Philip Jacobson, Jeff Ferry, Iain Jenkins, Janine di Giovanni, Rebecca Mead's, Boris Schapiro, Mark Wallington,
... week filled with nuns, puns, and sinners on the run Sonic boom goes Mega A hedgehog has advanced computer games, says Mark Edwards The Royal Opera House Theatre Royal Haymarket The Peter ...
1992 - Gale Group | Sunday Times HA GDA
Valeria Marigo, Clifford J. Tabin,
... us to use PTC as a marker for Sonic hedgehog response. The pattern of PTC expression suggests that Sonic hedgehog ...
Tópico(s): Themes in Literature Analysis
1996 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Giles Smith, Andrew Robson, Phil Yates, Alyn Shipton, Carol Lewis, Tom Braithwaite, Robert Dawson Scott, Andrew Billen, Robert Cole, Neelam Verjee, David Brown, Leo Lewis Asia Business Correspondent, Captain I. M. Peterson, Sir Michael Bichard, Martin Birchall, Frances Gibb Legal Editor, Gary Duncan, Alexandra Blair, James Rossiter Property Correspondent, David Rose, Robin Taylor-Hunt, Philip Howard, Hannah Betts, Camilla Cavendish, David Lister Scotland Correspondent, David Chater, Ben Hoyle Arts Reporter, James Bone, James Ducker, Richard Hobson One-Day Cricket Correspondent, Elizabeth Judge, Gabrielle Starkey, Patrick Kidd, Sam Marlowe, Wendy Ide, James Hider, Jeremy Whittle, Kevin Eason, Joe Joseph, Robin Pagnamenta, Ben Webster Transport Correspondent, Valerie Elliott Countryside Editor, Jane MacArtney, Norris Hoyt, Siobhan Kennedy, Michael Hornsell, Dominic Walsh, Dan Sabbagh Media Editor, Debra Craine, Rory Watson, Gary Jacob, Ken Russell, Tim Reid, Rosemary Bennett, John Gau, Dan Sabbagh, Richard Ford Home Correspondent, Alan Hamilton, Anatole Kaletsky, Phil Gordon, Rhys Blakely, Richard Lloyd Parry, David Hands, Jonathan Richards, Michael Glover, Adrienne May, Matt Dickinson Chief Football Correspondent, Greg Hurst, David Charter, Hugo Rifkind, Derwent May, James Mottram, Russell Kempson, Ed Potton, Austin Wright, Carola Long, Gary Duncan Economics Editor, Oliver Kay, David Lister, Sarah Vine, Mark Henderson Science Editor, Patrick Hosking Banking and Finance Editor, James Harding Business Editor, Rick Broadbent, Tom Baldwin, Stephen Burgen, James Rossiter, Sam Coates, Ann Treneman, David Robertson Business Correspondent, Rob Wright, Bernard Lagan, Neil Harman Tennis Correspondent, Raymond Keene, Adam Sage, Christine Buckley, Robert Crilly, Matt Hughes, Sarah Birke, Chas Hammond, Christine Buckley Industrial Editor, Jeremy Page, Chris Campling, Patrick Hosking, Christopher Martin-Jenkins Chief Cricket Correspondent, Damian Whitworth, Peter Dixon, Gabriel Rozenberg Economics Reporter, Nick Hasell, David Hands Rugby Correspondent, Kevin Maher, Winston Fletcher, Julian Muscat, Paul Simons, Dominic Kennedy, Mary Ann Sieghart, Robert Crampton, Steve Hawkes, Michele Kirsch, Craig Lord, Ian Johns, Emily Ford, Matthew Parris, Vice-Admiral Sir James Jungius, Alan Lee, Peter Riddell, Tim Capon, Tony Dawe, Canon Chris Chivers, Richard Beeston, Carly Chynoweth, Philip Webster, David Sanderson, David Sinclair, John Naish, Catherine Philp, Martin Waller, Chris Ayres, Henry Titley, Nigel Hawkes Health Editor, Sarah Butler, Katie Green, Dr Thomas Stuttaford, Sam Coates Political Correspondent, Stephen Dalton, Nicola Woolcock, Ben Hoyle, Bill Edgar, Frances Gibb, James Christopher, Alexandra Blair Education Correspondent, Owen Slot, Olav Bjortomt, Fiona Hamilton, Jan Raath, Fay Schopen, Richard Ford, Bryce Elder, Christopher Irvine,
... over Endesa block What he said Mario and Sonic head for Olympic showdown BT The hedgehog and the plumber How the video game icon ...
2007 - Gale Group | TDA
Anne‐Gaëlle Borycki, Lori Mendham, Charles P. Emerson,
... by the process of somite formation and a Sonic hedgehog signal. The Sonic hedgehog signal response genes, therefore, have important functions in regulating the initiation of the Sonic hedgehog response in newly forming somites and in regulating ...
Tópico(s): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
1998 - The Company of Biologists | Development
Tijuca Rio de Janeiro, Taki, Tara Palmer-Tomkinson's, Waldemar Januszczak, John Dugdale, Michael Prescott, Victoria McKee, Christopher Middleton, Barney Spender, Barbara Hall, Aa Gill, Royal Ballet, Donald MacGillivray, Michelene Wandor, Ellie Giles, Lewis Reed, John Peter, Emma Moore, Surf bikinis, Anthony Edwards, Alicia Wyllie Deputy Money Editor, Lesley White, John Jay, Christopher Somerville, Phillip Taylor, Emine Saner, Monica Crowley, Ivo Tennant, Abbey, Ferdinand Mount, Addison de Witt, S C Peterborough, Dr C Cole, Allan Brown, Lars Persson, David Smith, Ed Wallis's, David Eden, Edin Hamzic, Sally Payne, Chris Dignan, Nick Pitt, Donu Kogbara, Neil Wormald, E Warmington, Andrew Sullivan, Ruport stolner, Clive Davis, Vincent Kearney, Carol Sarler, Mary Wilson, Karen Robinson, K R, Dr Roger Henderson, Ivo Pogorelich, Andrew Grice Political Editor, Thrasy Petropolous, Peter Wardley, Tony Allen-Mills, Simon Wilde, Martin James, Robert Sandall, Eleanor Mills, Anthony Sattin, Steve Farrar, Andrew Nebel Director of Marketing, Robert Hewison, Peter Wilson, Roger Anderson, Angela Mollard, Philip Flaxton, Lucas Black, Norman Davies, Ann Widdecombe, Darcey Bussell, Philip Kingsley, L P, Damon Hill, Bill Hagerty, Sarah Toyne, David Hewson, Harvey Porlock, Yvonne Ridley, Margaret Coles, Hugh Canning, David Caims, Jeremy Clarkson, Peter Kemp, Edward Porter, Stewart Lee, John Waples Deputy City Editor, Michael Jones, Ms L B Peterborough, George Perry, Robin Marlar, Graham Otway, Hugh McManners Defence Correspondent, Nick Gardner, Shelley von Strunckel, Cl-P, A Francis, Naomi Campbell, Paul Ham, Stuart Wavell, Maggie Gee, Paul Donovan, William Shawcross, Veronica Masters, Sue Lawrence, Justin Cartwright, Sandra Kasalo, Stan Labovitch, Paul Driver, Derek Clements, L G, Peter Windsor, Ian Hawkey, Ian Chadband, Alex Ferguson, Christopher Morgan, Alicia Wyllie, Dr Tom Parry, John Ashelford Director, Michael Prescott Chief Political Correspondent, Tom Shone, Mark Edwards, Sarah Gracie, Susan Clark, Fiona McHugh, Mark Austin, Jack Epstein, Hugh McLlvanney, Nicholas Rufford Home Affairs Editor, Malcolm Gloak, Edward Crabtree, Phil Baker, Michael Riding, John Harlow Arts Correspondent, Hugo Barnacle, Lois Rogers, Bob Graham, Raymond Keene, John Karter, Stanley Stewart, Cosmo Landesman, Peter Davison, Andrew Roberts, Andrew Butcher, Tony Fernandes, Debbie Hill, Diana Wright, Andrew Ritchie, M Carmichael, Simon Willis, Nicholas Tucker, Chris Partridge, Stephen Jones, Richard Evans, Nick Cain, Fiery Donald, M Lowe, Natalie Graham, Andrew Smith, Paul Nuki, David Pleat, Pere Ubu, Amenda Ursell, Keith Wheatley, Claire Oldfield, David Walsh, Caroline Gascoigne, John Stern, Trevor Lewis, Jack Grimston, Ruport Steiner, Barry Simms, Rasselas, S F G, Stephen Armstrong, Christopher Goodwin, John Carlos, Paul Kavanagh, Josh Salzmann, R W Johnson, Sheryl Garratt, Diana, Roland White, Miss Jean Brodie, Dr John Hemming, Chatterley, Ruport Stolner, Rachel Cooke, John Travolta, Maurice Chittenden, Kevin Pratt, Andrew Lorenz Business Editor, Kevin Donovan, Judith O'Reilly, Ray Hutton, John Wilcockson, Jon Ungoed-Thomas, Andrew Rogers, Peter Watts, Susan Elkin, George Orwell, Michael Sheridan, Redgrave Crew, Sean Hargrave, Fay Weldon, David Starkey, John Harlow, Christine Webb, Matthew Lynn, Godfrey Smith, Ted Hughes, Ian Thomson, Bob Davis, Nia Williams, Mary Chalaye, J A, Andrew Alderson, John Waples, Gareth Jenkins, Roy Hattersley, A A Gill, Jeremy Hart, Andrew Stephen, Matthew Campbell, Lloyd Webber, John Carey, David Hutcheon, Rajeev Syal, Neil Hamilton, Nadine Meisner, Robert Johnston, Jim Clark, Stephen Pettitt, Trushar Barot, Cherry Norton, Robert Prior, Andrew Lorenz, Liam Clarke, David Wickers, Emily Jewsbury, Mark Hodson, Mary Henderson, Ray Perry, Rupert Steiner, Ali Stewart, Chris Lightbown, Lucy Broadbent, Hugh Pearman, Dave Selby, David Parsley, John Phillips, John Burns, David Smith Economics Editor, J R, Simon Trump, Zoe Linkson, Richard Nixon, Jonathan Aitken, Frank Taylor, Carey Scott, Stephen Boyd, Joanna Simon, Simon Howard, Dan Pearson, Dominic Rushe, Boris Schapiro, Adam Parsons,
... battle flag Saab Cambridge honours its forgotten women Sonic hedgehog alarm keeps death off roads Teletubby creator to earn £40m in US The adoption winners Infant adoption is discouraged but new ...
1998 - Gale Group | Sunday Times HA GDA
Bei‐En Chang, Patrick Blader, Nadine Fischer, Philip W. Ingham, Uwe Strähle,
... zebrafish, suggesting that axial is a regulator of sonic hedgehog transcription. The sonic hedgehog gene was cloned from zebrafish and its promoter ... identified a retinoic acid response element (RARE) in the sonic hedgehog upstream region which can be bound by retinoic ... in vitro and confers retinoic acid inducibility to the sonic hedgehog promoter in the HeLa cell system. Our results ... and retinoic acid receptors are direct regulators of the sonic hedgehog gene. Introduction Cell–cell signalling plays a crucial ...
Tópico(s): Epigenetics and DNA Methylation
1997 - Springer Nature | The EMBO Journal
Srikumar Sen, Boxing Correspondent, Michael Clark, Stock Market Correspondent, James Landale, Julia Llewellyn Smith, Anne Tully, Member, Tom Hewitt, Peter Middleton, Joanna Clark, Gillian Rowe, Geoffrey N. Silman, Srikumar Sen, boxing correspondent, Gerald Vinestock, Simon Barnes, Richard Ford, Home Correspondent, Tim Judah, Alexandra Frean, Media Correspondent, Stuart Freedman, John Diamond, Giles Gordon, Angela MacKay, Philip Howard, Drag queen, John Marriott, John Walters, James Bone, I. A. Shapiro, Nigel S. Cobb, Nicola Cole, Lynne Truss, Albert Dormer, David Flusfeder, Eve-Ann Prentice, Diplomatic Correspondent, Philip Bassett Industrial Editor, Joe Joseph, Robert Miller, Francesca Greenoak, David Rowland, Ruth Gledhill, Religion Correspondent, Steve May, Robin Hunt, John Hopkins, Golf Correspondent, Peter Ball, Ruth Gledhill, Graham Duffill, Nicholas Watt, Ireland Correspondent, Raymond Keene Chess Correspondent, Louise Taylor, Rob Hughes Football Correspondent, Jane MacQuitty's, Peter Waymark, Alan Hamilton, Robin Young, Robert Mitchell, Chairman, Jenny MacArthur, Michael Clark, Eve-Ann Prentice, Richard Scott, Dominic Mills, Anne Mcelvoy, Doug Sager, George Sivell Assistant Business Editor, Keith Pike, R. D. O'driscoll, Peter Davies, David Hands, Laurie Taylor, Charles Bremner, Russell Hewitson, Zoe Young, Margaret Fairburn, Jeremy Bennett, Sarah Bagnall, Christine Stone, Peter Barnard, Ramnick Shah, Derwent May, Anthony Lester, Sally Jones, Jessica Gorst-Williams, Geraldine Harrison, Sydney Friskin, Chad Varah, Nicholas Harling, David Miller, Richard Ford and Kevin Eason, Mark Almond, Ronald Riggs, Raymond Keene, Geoffrey Clarke, David Robinson, Peter Davalle, Leanne Benjamin, Emma Wilkins, David Nursaw, Paul Wilkinson, Richard Evans, Nigel Hawkes, Alice Thomson, Maggie McGill, Shannon W. Brock, Joan Cowper, Barry Pickthall, Doug Seger, Roger Boyes, Stephanie Billen, Jessica Douglas-Home, Humphry Berkeley, David Hands Rugby Correspondent, Julian Muscat, Nicholas Wood, Chief Political Correspondent, Andrew Pierce and Arthur Leathley, John Goodbody, Dominic Kennedy, Jane Bidder, Giles Whittell, Sara McConnell, Sarah Bagnall Insurance Correspondent, James Pringle, Matthew Parris, Ivor Herbert, Sara McConnell and Robert Morgan, Godfrey Smith, Clarissa Hyman, Ben MacIntyre, Sarah Jane Checkland, Sarah Marsh, Richard Beeston, Angela Buxton, Alan Jenkins, Simon Jenkins, Philip Pangalos, Michael Horsnell, Hyam MacCoby, Christian de Lisle, Christopher Elliott, Benedict Nightingale, Derwent May's, Tom Rhodes, Michael Hornsby Countryside Correspondent, Richard Morrison, Bea Cowan, Michael Henderson, Anne McElvoy, Lindsay Cook Deputy Business Editor, R. Wright, Fiona Beckett, George W. Keeling, P. Glaister, Matthew Bond, Vivian Russell's, Ronald F. Yule, Christian Dymond, Hilary Kingsley, Barry Hyman, Frances Bissell's, Edward Marriott, Melvyn Marckus,
... to First World War designs Deafened by the Sonic boom In the luerative Christmas market for video games, a small blue hedgehog is still the king Nikon Festive events Sales ...
1993 - Gale Group | TDA
Valeria Marigo, Matthew P. Scott, Ronald L. Johnson, Lisa V. Goodrich, Clifford J. Tabin,
... of Sonic hedgehog signaling. An important role of Sonic hedgehog is the regulation of anterior/posterior pattern in the developing ... not the ectoderm is the direct target of Sonic hedgehog signaling in the limb bud. Finally we demonstrate that induction of Patched requires Sonic hedgehog but, unlike Bone Morphogenetic Protein-2 and Hox ...
Tópico(s): Congenital limb and hand anomalies
1996 - The Company of Biologists | Development
Richard Harries, Chairman, Arthur Leathley, Transport Correspondent, R. Kristiansen, Ken Hughes, Nick Nuttall Environment Correspondent, Robert Cole, Michael Aylwin, Catherine Riley, Andrew Pierce, Olu Abiola, Chairman, Stephen Farrell and Arthur Leathley, Transport Correspondent, Rob Hughes, Simon Barnes, Alison ELLIOTCovernor, Julian Lee, Paul Hoggart, Claire McDonald, Bernard Kaukas, Frances Gibb, Legal Editor, Reports from the Bar Conference, Michael Evans Defence Editor, Philip Howard, Hilary Finch, Steve Branley, Norman De Mesquita, Mark Benham and Adam Sherwin, Uri Geller, Michael Paterson, Carla Quirighetti, James Landale, Political Correspondent, Michael Evans, Defence Editor, Eduard Fuller, David Robinson and Perry Cleveland-Peck, Tony Patrick, Stewart Tendler, Crime Correspondent, Jorge Elias, Tim Rodber, Fraser Nelson, Retail Correspondent, Robert Sheehan, Bridge Correspondent, Ernest A. Hounsell, Mark Benham, Pat Gibson, David McVay, Ruth Gledhill, Religion Correspondent, Nick Martin, Donald Hutera, Ruth Gledhill, Shirley English, John O'leary, Education Editor, Alasdair Reid, Michael Forrest, Raymond Keene Chess Correspondent, Keith Dugdale, Ross Dunn, Audrey Magee Ireland Correspondent, Rita Carter, Alan Hamilton, Robin Young, Mark Inglefield, Rodney Milnes, Alice Lagnado, Frederick Hutchinson, Tony Blair, James Landale Political Correspondent, Helen Rumbelow Medical Reporter, Ian Hughes, Keith Pike, Alix Ramsay, Tennis Correspondent, David Hands, Jean Glavany, Mark Giles, Gerald CORBETTChief Exeutive, Rodney Mlines, Lisa Armstrong Fashion Editor, Peter Barnard, Michael Howard, Christopher Pinsent, Paula Hawkins, Russell Kempson, Paul Durman, David Lister, Nicholas Harling, John Hopkins, Arthur Leathley and Clive Mathieson, Rob Wright, Stephen Wood, David Watts, Stuart Miles, Adam Jones, Raymond Keene, Adam Sage, Clive Mathieson, Matthew Pryor, Richardson of Calow Moderator, Matt Dickinson, Alison Kervin Rugby Editor, David Coffey, General Secretary, Oliver Holt, Richard Owen, Damian Whitworth, Jeremy Fletcher, Mick Hume, Roger Boyes, Nigel Hawkes, Science Editor, Martin Woods, Paul Fitzapatrick, Nick Hasell, Sydney Friskin and Cathy Harris, Oliver Holt, Football Correspondent, Christopher Massey, David Hands Rugby Correspondent, Roger Bootle, Jennifer O'Neill, Nick Szczepanik, John Goodbody, Simon Munk, Alan Copps, Alex O'Connell, Mel Webb, Witold Gutt, Kevin McCarra, Jennai Cox, Sean Hargrave, George Caulkin, Chris McGrath, Tim Wapshott, Walter Gammie, Peter Riddell, Oliver Chastney, Ray Hatley, Ian Brodie, Edward Karam, Tony Dawe, Michael Dynes, Fraser Nelson, Lea Paterson, Mark Henderson, Chris Ayres, Mark Baldwin, Roger Rowberry, Benedict Nightingale, Peter Smith Chairman, Nigel Powell, John B. Sheldon, Stephen Dalton, Bill Edgar, Valerie Grove, Adam Sherwin, Alex O'connell, Carl Mortished and David Lister, Richard Ford, John Bennett, Christopher Irvine, Christine Buckley, Industrial Correspondent,
... on ice are cute—but not so entertaining Sonic's bright new world Saga's hedgehog hits a new level, says Tim Wapshott Top Three Name their Most Popular Games Intershop The Times Methodika MBT Multiple Display Advertising Items PMR ...
1999 - Gale Group | TDA
Mieko Katsuura, Yoshiko Hosono-Sakuma, Masako Wagatsuma, Sachiko Yanagisawa, Makoto Okazaki, M Kimura,
... the animal cell-derived NH2-terminal domain of sonic hedgehog. The NH2-terminal deleted NH2-terminal domain of sonic hedgehog completely lost its activity, nevertheless it inhibited the alkaline phosphatase activity induced by the animal cell- ... the NH2-terminal deleted NH2-terminal domain of sonic hedgehog retains a receptor-binding ability and that the NH2-terminal peptide of the NH2-terminal domain of sonic hedgehog is necessary for its signal transduction.
Tópico(s): Epigenetics and DNA Methylation
1999 - Wiley | FEBS Letters
Kenji Shimamura, John L.R. Rubenstein,
... to the inductive signals from the prechordal plate, Sonic Hedgehog, the anterior neural ridge and FGF8. In sum, these ...
Tópico(s): Wnt/β-catenin signaling in development and cancer
1997 - The Company of Biologists | Development
Robert D. Riddle, Randy L. Johnson, Ed Laufer, Cliff Tabin,
... second limb. We have isolated a vertebrate gene, Sonic hedgehog, related to the Drosophila segment polarity gene hedgehog, which is expressed ... tissue into tissue with polarizing activity, concomitantly induces Sonic hedgehog expression in the anterior limb bud. Implanting cells that express Sonic ... cause ZPA-like limb duplications. Like the ZPA, Sonic hedgehog expression leads to the activation of Hox genes. Sonic hedgehog thus appears to function as the signal for anteroposterior patterning in the limb.
Tópico(s): Congenital limb and hand anomalies
1993 - Cell Press | Cell
Craig E. Nelson, Bruce Morgan, Ann C. Burke, Ed Laufer, Enrico DiMambro, L. Charles Murtaugh, Ellen Gonzales, Lino Tessarollo, Luis F. Parada, Cliff Tabin,
... response of the limb mesoderm to Sonic hedgehog. Sonic hedgehog (the patterning signal from the Zone of Polarizing Activity) ... upon the temporal context of the mesoderm receiving the signal. Misexpression of Sonic hedgehog also reveals that Hoxb-9, which is normally ... portion of the leg, is not affected by Sonic hedgehog and hence is not required to pattern the skeletal elements of the lower leg.
Tópico(s): Congenital heart defects research
1996 - The Company of Biologists | Development
Karine Loulier, Martial Ruat, Élisabeth Traiffort,
... six days following the adenovirus‐mediated delivery of Sonic hedgehog into the lateral ventricle, newly generated cells in the cerebral ... corpus callosum can be increased upon delivery of Sonic hedgehog proteins and highlight the potential capacity of the adult brain to mobilize ...
Tópico(s):
2006 - Wiley | Journal of Neurochemistry
E.M. Torres, Christelle Monville, Pedro R. Löwenstein, María G. Castro, Stephen B. Dunnett,
... of adenoviral vectors to deliver the differentiation factor sonic hedgehog or the glial cell line-derived neurotrophic factor GDNF to ... into the vector-transduced striatum. Pre-treatment with the sonic hedgehog vector produced a three-fold increase in the numbers of tyrosine hydroxylase-positive (presumed dopaminergic) cells ...
Tópico(s): Nerve injury and regeneration
2005 - Elsevier BV | Brain Research Bulletin
Jing Yu, Thomas J. Carroll, Andrew P. McMahon,
... mesenchyme, but does not mediate the effects of sonic hedgehog in the control of mesenchymal proliferation.
Tópico(s): Urological Disorders and Treatments
2002 - The Company of Biologists | Development
Heather M. Young, Lincon A. Stamp, Robert M.W. Hofstra,
... recent study even showed that high concentrations of sonic hedgehog at the villus tips are indirectly responsible for restricting the ... Lui V.C. Sham M.H. et al.Sonic hedgehog regulates the proliferation, differentiation, and migration of enteric neural crest ... 2000; 127: 2763-2772Crossref PubMed Google Scholar while sonic hedgehog promotes the proliferation of zebrafish enteric neural progenitors in vivo13Reichenbach ... Lui V.C. Sham M.H. et al.Sonic hedgehog regulates the proliferation, differentiation, and migration of enteric neural crest ...
Tópico(s): Digestive system and related health
2015 - Elsevier BV | Gastroenterology
Hoi-Wing Leung, Eunice Y. Lau, Carmen Oi Ning Leung, Martina Mang Leng Lei, Etienne Ho Kit Mok, Victor Ma, William C. Cho, Irene Oi‐Lin Ng, Jing‐Ping Yun, Shaohang Cai, Hua Yu, Stephanie Ma, Terence K. Lee,
... hedgehog homolog (SHH), which triggers activation of the sonic hedgehog pathway. The effect of NRF2 knockdown was eliminated upon administration ... Our study suggests a novel regulatory mechanism for the canonical sonic hedgehog pathway that may function through the NRF2/SHH/GLI signaling axis, thus mediating T- ...
Tópico(s): Epigenetics and DNA Methylation
2020 - Elsevier BV | Cancer Letters
Stephen R.F. Twigg, Robert B. Hufnagel, Kerry A. Miller, Yan Zhou, Simon J. McGowan, John Taylor, Jude Craft, Jenny C. Taylor, Stephanie L. Santoro, Taosheng Huang, Robert J. Hopkin, Angela F. Brady, Jill Clayton‐Smith, Carol L. Clericuzio, Dorothy K. Grange, Leopold Groesser, Christian Hafner, Denise Horn, I. Karen Temple, William B. Dobyns, Cynthia J. Curry, Marilyn C. Jones, Andrew O.M. Wilkie,
... trichoblastoma and medulloblastoma suggest an etiologic role of the sonic hedgehog-patched-GLI pathway.Am. J. Med. Genet. A. ... trichoblastoma and medulloblastoma suggest an etiologic role of the sonic hedgehog-patched-GLI pathway.Am. J. Med. Genet. A. ... trichoblastoma and medulloblastoma suggest an etiologic role of the sonic hedgehog-patched-GLI pathway.Am. J. Med. Genet. A. ... trichoblastoma and medulloblastoma suggest an etiologic role of the sonic hedgehog-patched-GLI pathway.Am. J. Med. Genet. A. ...
Tópico(s): Genetic and rare skin diseases.
2016 - Elsevier BV | The American Journal of Human Genetics
Sheree A. Ting‐Berreth, Cheng‐Ming Chuong,
... is required for the induction and maintenance of Sonic hedgehog in the epithelial placodes. In scaleless mutant, Sonic hedgehog is absent in the apteric region and aberrantly expressed in the mesenchyme ... the abnormal feather ridge. These findings suggest that Sonic hedgehog mediates key interactions between the epithelium and mesenchyme during feather morphogenesis. © 1996 Wiley- ...
Tópico(s): Skin and Cellular Biology Research
1996 - Wiley | Developmental Dynamics