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Artigo Revisado por pares

O. Don Hermes, D. Ritchie,

... suites of Ordovician to Carboniferous age (Blue Hill, Spencer Hill, and Wamsutta suites). Each suite exhibits unique petrographic ... exhibit distinct flow-banding. (2) Blue Hill and Spencer Hill rocks: mainly lava flows; abundant perthite and quartz ... the Lynn/Mattapan suite, the Blue Hill and Spencer Hill rocks exhibit higher concentrations of Rb, Y, Zr, ...

Tópico(s): Mineralogy and Gemology Studies

1997 - Wiley | Geoarchaeology

Jornais Acesso aberto

H. S. Holland, J. A. Hobson, Michael Field, Julia Cartwright, Charles Gore, F. W. Robertson, Percy Dearmer, A. H. Sayce, Evelyn Sharp, A. M. Wakefield, A. L. Lilley, J. Spencer Hill, R. F. Horton, R. L. Ottley,

Cover: The Commonwealth 1896. Table of contents: Contents. Essay: Notes of the Month, The Commonwealth, Emerson as Philosopher, Illustrations, Christmas ...

1896 - Gale Group | NCCO BritishPolitics

Artigo Acesso aberto Revisado por pares

Jerry Li, Nicholas Purser, Joanna Liwocha, Daniel C. Scott, Holly A. Byers, Barbara Steigenberger, Spencer Hill, Ishita Tripathi‐Giesgen, Trent Hinkle, Fynn M. Hansen, J. Rajan Prabu, Senthil K. Radhakrishnan, Donald S. Kirkpatrick, Kurt M. Reichermeier, Brenda A. Schulman, Gary Kleiger,

Highlights•UBE2R E2s preferentially target CUL2-based CRL2 substrates•CRL2-dependent PROTAC efficiency correlates with UBE2R-family E2 levels in cells•Cryo-EM reveals a UBE2R2-CRL2 interface that underlies geometric substrate selection•A dedicated poly-ubiquitin chain extending E2 is reprogrammed to prime CRL2 substratesSummaryCullin-RING ligases (CRLs) ubiquitylate specific substrates selected from other cellular proteins. Substrate discrimination and ubiquitin transferase activity were thought ...

Tópico(s): Peptidase Inhibition and Analysis

2024 - Elsevier BV | Molecular Cell

Jornais Acesso aberto

Edward Lucie-Smith, Barbara Hall, Joan Bakewell, Patrice Chaplin's, Charlotte Bingham, Paul Nelson, Richard Ellis, Bel Mooney, Jon Swain, Graham Kelly, James Lattin, Rob Hughes, John Peter, Andrew Grice Political Correspondent, Eric Dymock, Norman MacRae, A Turnock, Danby Bloch, Cameron MacKintosh, John Diamond, Graham Rose, Norman Howell, Tudor Gates, David Smith, Norman Black, William Green, Olivier Todd, G. B. Trudeau, Julian Joyce, Dr Philip Hopkins, Dalbert Hallenstein, Cal McCrystal, Mark Ellis, Mark Hosenball, Ron Hoggard, Edward Welsh, Tim Kirby, Charles Welldon, Geordie Greig, Patrick Stoddart, Susan Marling, Robert Sandall, Iain Johnstone, David Brierley, Anthony Pearson, Irwin Stelzer, Peter Godwin, Andrew Sheppard, Ivan Fallon, Deryk Brown, Mark Ottaway, Geordie Greig Arts Correspondent, Joe Irving, Malcolm Bradbury, Valerie Elliott, Jane Bird, Muriel Spark, Alison Smith Political Staff, Dr Crypton, John Le Carré, Gareth Daniels, Doreen Tayler, Egon Ronay, Hugh Canning, Baby Ballerina, Susan Crosland, David Cairns, Peter Kemp, Simon kaminsky, Norman Harris, Andrew Wilski, Cynthia Miller, Julia Neuberger, Geoff Whitten, Marise Morland, Robert Harris, Michael Jones, Geoffrey Cannon, Frank Barrie, Patrick Horton, George Perry, John Cassidy, Philip Robinson, Peter Seabrook, Jill Wright, Christine Toomey, David Irving, Bernard Cafferty, Jon Freeman, Paul Donovan, Janette Marshall, Bernard Richards, Frances Spalding, Amit Roy, Dr W Leat, Frank Perryman, Jonathan Todd, Biddy Collyer, Jeff Randall, Robert Skidelsky, James Adams, David Hughes, Austin MacCurtain, David Leppard, Tim Rayment, Sally Forrest, David Cross, Patricla Mowbray, Joan Forman, Rufus Olins, David Lawrenson, John Hopkins, Askold Krushelnycky, Martin Jacques, Anne-Elisabeth Moutet, Brian Walden, Owen Oyston, Gareth David, D Fitzpatrick, Kate Saunders, Brian Masters, Malcolm Winton, Greg Hadfield, Craig Brown, Pamela Shirras, Andrew Lorenz Industrial Editor, Stephen Jones, Anthony Cavendish, Charles Oulton Home Affairs Correspondent, Brian Deer, Meriel McCooey, Norman Lebrecht, Richard Palmer, Keith Wheatley, Miranda Seymour, Ian Birrell, Safa Haeri, Dilys Powell, Colin McDowell, Ben Pimlott, Chris Jones, Brough Scott, Cilla Kent, Alison Beckett, Tony Rocca, Caroline McGhie, Jackson Hole, Richard Woods, Pauline Collins, Louise Branson, Edwin Mullins, Frances Rafferty, Marion Hume, Maurice Chittenden, Joy Melville, Ian Dunning, John Walsh, Elisabeth De Stroumillo, David Hughes Chief Political Correspondent, Brian MacArthur, Mel Webb, John Harrison, G Whitten, Roger Clarke, Mary Flanagan, Tomasz Starzewski, Peter Mayle, Ian Thomson, Philip Beresford, Susannah Herbert, Matthew Reisz, Charles Oulton, Julie Roberts, Brian Clarke, Brian Glanville, Matthew Campbell, Carrie Segrave, Chris Dighton, Edward Pearce, R. H. Hughes, Simon Jenkins, Godfrey Golzen, Norman Cumming, Gareth David Deputy City Editor, Andrew Lorenz, John Furbisher, Liam Clarke, David Wickers, Chris Maume, Marina Vaizey, Chris Lightbown, Jeff Randall City Editor, Margaret Park, Angela Long, Frank Field, Dorothy Wade, David Smith Economics Editor, Penny Perrick, Tony Hetherington, Laurence Lerner, Rod Hackney, Chris Blackhurst, Joanna Simon, Nigel Dempster, Iain Jenkins, James Adams Defence Correspondent, Hilary Bristow, J Schwieso, Boris Schapiro,

... Anglian Water Services Ltd. AGB Research PLC SMA Spencer Munro Selection Hill Samuel Investment Services Touche Ross KPMG Peat Marwick ...

1989 - Gale Group | Sunday Times HA GDA

Artigo Acesso aberto Revisado por pares

Kheewoong Baek, David T. Krist, J. Rajan Prabu, Spencer Hill, Maren Klügel, Lisa-Marie Neumaier, Susanne von Gronau, Gary Kleiger, Brenda A. Schulman,

Eukaryotic cell biology depends on cullin–RING E3 ligase (CRL)-catalysed protein ubiquitylation1, which is tightly controlled by the modification of cullin with the ubiquitin-like protein NEDD82–6. However, how CRLs catalyse ubiquitylation, and the basis of NEDD8 activation, remain unknown. Here we report the cryo-electron microscopy structure of a chemically trapped complex that represents the ubiquitylation intermediate, in which the neddylated CRL1β-TRCP promotes the transfer of ubiquitin from ...

Tópico(s): Glycosylation and Glycoproteins Research

2020 - Nature Portfolio | Nature

Artigo Acesso aberto Revisado por pares

Spencer Hill, Kurt M. Reichermeier, Daniel C. Scott, Lorena Samentar, Jasmin Coulombe‐Huntington, Luisa Izzi, Xiaojing Tang, Rebeca Ibarra, Thierry Bertomeu, Annie Moradian, Michael J. Sweredoski, Nora B. Caberoy, Brenda A. Schulman, Frank Sicheri, Mike Tyers, Gary Kleiger,

The cullin-RING ligases (CRLs) form the major family of E3 ubiquitin ligases. The prototypic CRLs in yeast, called SCF enzymes, employ a single E2 enzyme, Cdc34, to build poly-ubiquitin chains required for degradation. In contrast, six different human E2 and E3 enzyme activities, including Cdc34 orthologs UBE2R1 and UBE2R2, appear to mediate SCF-catalyzed substrate polyubiquitylation in vitro. The combinatorial interplay of these enzymes raises questions about genetic buffering of SCFs in human cells ...

Tópico(s): Autophagy in Disease and Therapy

2019 - eLife Sciences Publications Ltd | eLife

Jornais Acesso aberto

FROM OUR BRIDGE CORRESPONDENT, FROM OUR MUSEUMS CORRESPONDENT, BY OUR LABOUR CORRESPONDENT, FROM OUR CORRESPONDENT, BY OUR PARLIAMENTARY CORRESPONDENT, FROM OUR OWN CORRESPONDENT, BY OUR AERONAUTICAL CORRESPONDENT, BY OUR DIPLOMATIC CORRESPONDENT, H. J. STANLEY., W. F. GRIMES, , SIDNEY SALOMON., From Our Correspondent, From Our United Nations Correspondent, FROM OUR SPECIAL CORRESPONDENT, From Our Own Correspondent, THOS. A. M. BARNETT, Professor of Old Testament, Wycliff College, Toronto, Canada., G. G. WILLIAMS. 52, Cranmer Court, Sloane Avenue, S.W.3., W. K. HASELDEN. 11, Lee Road, Aldeburgh, Suffolk, May 18., W. W. MUIR., ROBERT R. HYDE. Glevering, Beech Road, Haslemere, Surrey., T. W. ELMHIRST. 4, Pelham Crescent, S.W.7., By Our Museums Correspondent, CHARLES C. REID. 57, Blackwater Road, Eastbourne, May 18., GORDON SMITH, Secretary, Association of British Pharmaceutical Industry. Tavistock House South, Tavistock Square, W.C.1., CHARLES HOBHOUSE. Monkton Farleigh, Bradford-on-Avon, Wiltshire., T. P. CAMERER CUSS. 3, Spencer Hill, Wimbledon, S.W.19., BY OUR HORTICULTURAL CORRESPONDENT, Our Bonn Correspondent reports, A correspondent writes:-, L. S. A. writes:-, Our Wellington Correspondent reports, H. M. S. writes:-, FROM A CORRESPONDENT, FROM OUR CRICKET CORRESPONDENT, FROM OUR POLO CORRESPONDENT, BY OUR ROWING CORRESPONDENT,

Births. Marriages. Deaths. Classified Advertising: John Barker and Co. Kensington., Theatres, Travel. Property: Property Market, Rickeard, Green & Michelmore., ...

1953 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Spencer Hill, Joseph S. Harrison, Steven M. Lewis, Brian Kuhlman, Gary Kleiger,

Lysine selectivity is of critical importance during polyubiquitin chain formation because the identity of the lysine controls the biological outcome. Ubiquitins are covalently linked in polyubiquitin chains through one of seven lysine residues on its surface and the C terminus of adjacent protomers. Lys 48-linked polyubiquitin chains signal for protein degradation; however, the structural basis for Lys 48 selectivity remains largely unknown. The ubiquitin-conjugating enzyme Ube2R1/2 has exquisite ...

Tópico(s): Protein Degradation and Inhibitors

2016 - Taylor & Francis | Molecular and Cellular Biology

Jornais Acesso aberto

Anthony Burgess, Charles Raw, Richard Buckle, John Fryer, M. Harper, Evelyn Irous, Harold Hobson, Tony Dave, Brian F. Hicks, Kenneth Pearson, James Poole, Graham Rose, Antony Terry, (Mrs) Kathleen Short, Julian Symons, Cedrick Venables, Philip Oakes, F. W. Glassborow, Sally Jenkinson, Vivian Lewis, John Russell, Richard Milner, Mark Byron, Max Marquis, Timothy Giles, Derek Prouse, Douglas Parker, Derek Jewell, Henry, Patrick Campbell, Brian Jackson, John Ballantine, Brain Glanville, T. W. A. Pike, Frank Giles, John Chartres, Robin May, Cyril Connolly, Laurence Ray, Boris Schapiro, J. M. Imman, Maxwell Boyd, Helena Rubinstein, Evelyn Irons, Andrew Hale, Oscar Turnill, Patrick B. Easen, Derrik Mercer, Peter Wilsher, Harry Bloom, David Blake, Richard Garrick, Desmond Shawe-Taylor, Molson Chairman, Lyman Andrews, R. Davey, M. Neil Holmes, Stephen Fay Labour Correspondent, Alexander Mitchell, Lanning Roper, Dilys Powell, S. R. Shalson, Richard Hughes, Felix Aprahamian, Lan Peebles, Robin Sanders, Ian Nairn, Margaret Costa, Henry Longhurst, Lewis Chester, James Margach Political Correspondent, Derek Humphry, Michael Moynihan, Brian Glanville, Nicholas Harman, Graham Searjeant, J E Tye Secretary, C. H. O'd. Alexander, Tim Devlin, Maurice Wiggin, Nicholas Faith, Michael Parkinson, Margery Fisher, (Dr) B G Kelly, Harlow Unger, Malcolm Crawford, Muriel Bowen,

... Classified Advertising Items Multiple Display Advertising Items Henry Spencer & Sons Stooke, Hill & Co. Multiple Classified Advertising Items Solid Muldoons Collecting ...

1969 - Gale Group | Sunday Times HA GDA

Artigo Acesso aberto Revisado por pares

Daniella Sandoval, Spencer Hill, Amy Ziemba, Steven M. Lewis, Brian Kuhlman, Gary Kleiger,

In the ubiquitin-proteasome system, protein substrates are degraded via covalent modification by a polyubiquitin chain. The polyubiquitin chain must be assembled rapidly in cells, because a chain of at least four ubiquitins is required to signal for degradation, and chain-editing enzymes in the cell may cleave premature polyubiquitin chains before achieving this critical length. The ubiquitin-conjugating enzyme Cdc34 and ubiquitin ligase SCF are capable of building polyubiquitin chains onto protein ...

Tópico(s): Endoplasmic Reticulum Stress and Disease

2014 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Amy Ziemba, Spencer Hill, Daniella Sandoval, Kristofor J. Webb, Eric J. Bennett, Gary Kleiger,

Together with ubiquitin ligases (E3), ubiquitin-conjugating enzymes (E2) are charged with the essential task of synthesizing ubiquitin chains onto protein substrates. Some 75% of the known E2s in the human proteome contain unique insertions in their primary sequences, yet it is largely unclear what effect these insertions impart on the ubiquitination reaction. Cdc34 is an important E2 with prominent roles in cell cycle regulation and signal transduction. The amino acid sequence of Cdc34 contains an ...

Tópico(s): Cancer-related Molecular Pathways

2013 - Elsevier BV | Journal of Biological Chemistry

Jornais Acesso aberto

Srikumar Sen, Boxing Correspondent, Victoria McKee, Richard Jeffrey, Sarah Jane Checkland Saleroom Correspondent, Graham Chainey, Nicholas Wood, Political Correspondent, Edward Gorman Ireland Correspondent, Philip Rhodes, John O'leary Education Correspondent, Bill Frost, Chris August, Gordon Allan, E. W. Smith, Sheila Gunn, Political Correspondent, kari knight, Philip Howard, Ian Murray, Jeremy Kingston, Clive Davis, Carol Leonard, Lynne Truss, Albert Dormer, Srikumar Sen, Richard Streeton, Ross Tieman and Lulu Yu, Ingrid Hunt, Stuart Jones Football Correspondent, Stewart Tendler, Crime Correspondent, Gordon Nurse, Carl Garner, Michael Bourdeaux (Director), Ray Clancy, Ivor Gowan, Liza Donaldson and Ross Tieman, Jeremy Laurance, Health Services Correspondent, Martin Fletcher, Michael Dynes Transport Correspondent, Abby Tan, Mitchell Platts, Mitchell Platts, Golf Correspondent, Bruce Clark, Peter Stothard, US Editor, Debra Craine, Ivor Crewe, Louise Taylor, Rachel Kelly, Richard Evans, Racing Correspondent, Ruth Gledhill Religion Correspondent, Tony Tidmarsh, Robert Seely, Martin Barrow, Nick Nuttall Technology Correspondent, Michael Evans, Defence Correspondent, Frances Gibb and Ronald Faux, Alan Hamilton, Barbara Woodcock, Jenny MacArthur, Michael Clark, Philip Robinson, John Young, David Hands, Charles Bremner, John Percival, Peter Barnard, Lord St John of Fawsley, R. A. Hurst, Sir Robert Rhodes James, John McAnally, Grantley, Michael Latham, Director, Nicholas Harling, Marie Colvin and Richard Beeston, Frances Benn, Melinda Wittstock Media Correspondent, Anatole Kaletsky, Economics Editor, Robin Oakley Political Editor, Gillian Bowditch, Mitchell Platts Golf Correspondent, David Faull, Alan Toogood, Horticulture Correspondent, Brian Lynch, Robin Oakley, Political Editor, David Powell Athletics Correspondent, Jonathan Prynn, Raymond Keene, Chess Correspondent, Gerald Dix, Peter Stothard, Paul Wilkinson, Richard Evans, Nigel Hawkes, Gillian Bowditch and Neil Bennett, Brenda Fowler, Craig Seton, Patricia M. Roberts, Barry Pickthall, Ian Ross, Jeremy Kingston's, Keith MacKlin, Arthur Goldstuck, Richard Duce, John Goodbody, David Young, Philip Webster Chief Political Correspondent, Edward Gorman, Ireland Correspondent, Christopher Walker, James Pringle, Robert Crampton, Michael Grosvenor Myer, Colin Narbrough, Economics Correspondent, George Hill, Matthew Parris, Graham Searjeant Financial Editor, Bill Burroughs, Michael S. Moss, Raymond O'malley, Peter Riddell, Michael Phillips, David Shepherd, Kilmaine, Melinda Wittstock, Martin Waller, Michael Horsnell, Alan Coren, Benedict Nightingale, Edward Ashpole, Richard Morrison, Chris Moore, John Phillips, Matthew Bond, Colin Campbell, David Hands, Rugby Correspondent, Colin McQuillan, Jamie Dettmer and Corinne Schmidt, Mary Dejevsky, Richard Allen,

... and sordid lives of Mafia… The marks of Spencer's reign George Hill considers the inheritance of the 9th Earl Spencer and whether his management of Althorp will be ...

1992 - Gale Group | TDA

Artigo Revisado por pares

John Spencer Hill,

(2003). A History of Contemporary Italy: Society and Politics, 1943–1988. History: Reviews of New Books: Vol. 31, No. 3, pp. 115-115.

Tópico(s): Italian Fascism and Post-war Society

2003 - Taylor & Francis | History Reviews of New Books

Imagens Acesso aberto

Arthur Thomas Dean,

... Arms Hotel, Westerham, Kent, July 24th 1893 Mr. Spencer Read, 47, Brook Hill Road, Woolwich, London SE Included in the Group, ...

0000 - Gale Group | NCCO Photography

Artigo Revisado por pares

John Spencer Hill,

Tópico(s): European history and politics

2001 - Taylor & Francis | History Reviews of New Books

Artigo Revisado por pares

John Spencer Hill,

Tópico(s): Italian Fascism and Post-war Society

1998 - Taylor & Francis | History Reviews of New Books

Artigo Revisado por pares

Irwin M. Feuerstein, D L Jicha, Harvey I. Pass, Catherine K. Chow, Rong Chang, Alexander Ling, Spencer Hill, Andrew J. Dwyer, William D. Travis, Mark E. Horowitz,

The sensitivity of magnetic resonance (MR) imaging for detection of pulmonary metastases in 11 patients scheduled for thoracotomy and curative resection of metastases was evaluated with a prospective, controlled study. MR imaging performed at 0.5 T was compared with chest radiography, computed tomography (CT), and thoracotomy in 12 cases. (One patient had two separate occurrences of pulmonary metastases.) All images were interpreted in blinded fashion. When all MR sequences were interpreted together, ...

Tópico(s): Atomic and Subatomic Physics Research

1992 - Radiological Society of North America | Radiology

Artigo Acesso aberto Revisado por pares

Naser G. A. Mahfouz, Spencer A. Hill, Huan Guo, Yi Ming,

Abstract Marine cloud brightening is a proposal to counteract global warming by increasing sea salt aerosol emissions. In theory, this increases the cloud droplet number concentration of subtropical marine stratocumulus decks, increasing cloud brightness and longevity. However, this theoretical progression remains uncertain in coupled climate models, especially the response of liquid water path and cloud fraction to aerosol seeding. We use the GFDL CM4 climate model to simulate marine cloud brightening ...

Tópico(s): Atmospheric Ozone and Climate

2023 - American Geophysical Union | Geophysical Research Letters

Jornais Acesso aberto

David Wade, DJM, Anne Weitzman Chairman, Shirley Lancaster, Anne Billson, Richard Clegg, Simon Barnes, Julian Rose, Derek Ezra, Thomson Prentice and Peter Davenport, Gordon Allan, Elizabeth Young, Sheridan Morley, Robert Carr, Michael Stevenson, Sally Brompton, Hilary Finch, Ian Murray, Ivan Lawrence, Michael Binyon, Jeremy Kingston, Mandarin (Michael Phillips), Richard Evans, Media Editor, Carol Leonard, Dessa Trevisan, Michael McCarthy, Gerald Davies, Bernard Levin, Bryan Stiles, Sam Kiley Higher Education Reporter, David Wild, Michael Tate, Alan Lorimer, Roland Rudd, Employment Affairs Reporter, Stephen Hannah, D. G. Franklin, John Ballantine, Rodney Cowton, Transport Correspondent, Roland Rudd Employment Affairs Reporter, Douglas Broom, Peter Waymark, Ray Kennedy, E. P. Smith (Managing Director), Marcia Barinaga, Michael Clark, John Young, Graham Calderwood, Tracey Newman and C. Mallia, Kevin Eason Motoring Correspondent, John Percival, Rex Bellamy, Tennis Correspondent, Martin Fletcher Political Reporter, Humphrey Hawksley, Teresa Hickley, Harvey Elliott, Air Correspondent, Steven Downes, Harry Debelius, Sydney Friskin, Nicholas Harling, Robin Pittman, Head Master, Dennis Signy, Chris Thau, Mitchell Platts Golf Correspondent, Wolfgang Münchau, Christopher Goulding, Robin Oakley, Political Editor, Craig Brown, John Morris, Andrew McEwen, Diplomatic Correspondent, Phil McLennan, Sheila Gunn, Political Staff, Ruth Gledhill and Jill Sherman, Stewart Tendler, Crime Reporter, Martin Searby, Adrian Laverty, Maxwell Newton, F. J. O'Donovan, Ian Ross, Geoffrey Foster, Sheila Gunn Political Staff, Derek Harris, Industrial Editor, Caldecote, Brian Beel, Keith MacKlin, David Hands Rugby Correspondent, Christopher Fryling, Pat Butcher, Athletics Correspondent, John Gregson, Christopher Walker, George Hill, Srikumar Sen Boxing Correspondent, Graham Searjeant, Financial Editor, Robert Matthews, Technology Correspondent, Clive White, Conrad Jameson, Jack Straw, Sarah Jane Checkland Art Market Correspondent, Stanley of Alderley, Keith Blackmore, John Ransley, David Walker, Stephen Pettitt, Frances Gibb Legal Affairs Correspondent, Andrew McEwen and Hazhir Teimourian, David Tytler, Education Editor, Kenneth Morgan, Director, Richard Morrison, David Powell, Anne McElvoy, Vince Wright, Andrew Morgan and Peter Davenport, Penny Perrick, Colin Campbell, David Young Energy Correspondent, Richard Ford, Mark Dunn, Rodney Lord Economics Editor, Mary Dejevsky, D. G. M. Gordon,

... to grasp the realities of 1992, reports George Hill Haddon Spencer Mortgages The New Britannica Palate coups Your Chance ...

1989 - Gale Group | TDA

Artigo Acesso aberto Revisado por pares

Anita L. Ray, Robert A. Nofchissey, Maaz Khan, Megan A. Reidy, Megan R. Lerner, Xiangyan Wu, Shaoxuan Guo, Spencer L. Hill, Nathaniel Weygant, Sarah F. Adams, Eliseo F. Castillo, William L. Berry, Michael B. Stout, Katherine T. Morris,

Women with colorectal cancer (CRC) have a significant survival advantage over men. Sex influences on the tumour microenvironment (TME) are not well characterised, despite the importance of immune response in CRC. We hypothesised that sex-divergent immune responses could contribute to survival.Using a murine model of metastatic CRC, we examined T cells, macrophages, and cytokines locally and systemically. TME and serum cytokines were measured by multiplex bead-based arrays, while FCA was used to identify ...

Tópico(s): Immune Cell Function and Interaction

2020 - Springer Nature | British Journal of Cancer

Artigo Revisado por pares

Spencer A. Hill,

Tópico(s): Meteorological Phenomena and Simulations

2019 - Springer Science+Business Media | Current Climate Change Reports

Outros Acesso aberto

E. Spencer Pratt,

... 5, 1897-Dec. 29, 1898 Letter. From E. Spencer Pratt. To Honorable David J. Hill. Singapore.

0000 - Gale Group | NCCO AsiaWest

Artigo Acesso aberto Revisado por pares

Spencer A. Hill, Simona Bordoni, Jonathan L. Mitchell,

We consider the relevance of known constraints from each of Hide's theorem, the angular momentum conserving (AMC) model, and the equal-area model on the extent of cross-equatorial Hadley cells. These theories respectively posit that a Hadley circulation must span: all latitudes where the radiative convective equilibrium (RCE) absolute angular momentum ($M_\mathrm{rce}$) satisfies $M_\mathrm{rce}>\Omega a^2$ or $M_\mathrm{rce}<0$ or where the RCE absolute vorticity ($\eta_\mathrm{rce}$) satisfies $f\eta_\mathrm{ ...

Tópico(s): Quantum chaos and dynamical systems

2019 - American Meteorological Society | Journal of the Atmospheric Sciences