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Artigo Revisado por pares

Daniel A. Spyker, Emily Harvey, B Harvey, Alice Harvey, Barry H. Rumack, Carl C. Peck, A ATKINSONJR, Raymond L. Woosley, D. R. Abernethy, Louis R. Cantilena,

... clinical pharmacology information in drug labeling Daniel A. Spyker PhD, MD, Corresponding Author Daniel A. Spyker PhD, MD [email protected] Purdue Pharma L.P., ... for more papers by this author Daniel A. Spyker PhD, MD, Corresponding Author Daniel A. Spyker PhD, MD [email protected] Purdue Pharma L.P., ...

Tópico(s): Pharmacovigilance and Adverse Drug Reactions

2000 - Wiley | Clinical Pharmacology & Therapeutics

Jornais Acesso aberto

WILLIAM KNIGHT., T. E. HOLLAND., W. F. G. SANDWITH, , E. A. MANCHESTER., F. E. KENSINGTON., H. RUSSELL WAKEFIELD., ARNO SCHMIDT., THE WRITER OF THE ARTICLE.,

... Of Sherbrooke, Continental Tyres, London Chief Station:, Famous Spyker Cars, Chicago, Rock Island, And Pacific Railroad Company., ...

1908 - Gale Group | TDA

Artigo Revisado por pares

Owen Middleton,

... 44(6-7): 803–932. 22 Bronstein AC, Spyker DA, Cantilena LR Jr, Green J, Rumack BH, ... 2007; 45(8): 815–917. 23 Bronstein AC, Spyker DA, Cantilena LR Jr, Green JL, Rumack BH, ... 2008; 46(10): 927–1057. 24 Bronstein AC, Spyker DA, Cantilena LR Jr, Green JL, Rumack BH, ...

Tópico(s): Epilepsy research and treatment

2011 - Wiley | Journal of Forensic Sciences

Revisão

Jay Boyd Best, Michio Morita,

... J Exp Zool 187: 345–374, 1974. 35 Spyker JM, Smithberg M: Effects of methylmercury on perinatal ... in mice. Teratology 5: 181–190, 1972. 36 Spyker JM: Behavioral teratology and toxicology. In B Weiss, ... York: Plenum Press, 1972, pp 311–349. 37 Spyker JM: Subtle consequences of methylmercury exposure. Teratology 5: ...

Tópico(s): 3D Printing in Biomedical Research

1982 - Wiley | Birth Defects Research

Artigo Revisado por pares

Joseph A. Kwentus, Robert Riesenberg, Morteza Marandi, Raymond A Manning, Michael H. Allen, Robert Fishman, Daniel A. Spyker, John H. Kehne, James V. Cassella,

... Marandi M, Manning RA, Allen MH, Fishman RS, Spyker DA, Kehne JH, Cassella JV. Rapid acute treatment ...

Tópico(s): Schizophrenia research and treatment

2012 - Wiley | Bipolar Disorders

Carta Acesso aberto Revisado por pares

Richard C. Dart,

... 9 million calls for information.4Bronstein A.C. Spyker D.A. Cantilena Jr, L.R. et al. ... 2006NationalCase clusters reported from 26 states4Bronstein A.C. Spyker D.A. Cantilena Jr, L.R. et al. ...

Tópico(s): Pharmacology and Obesity Treatment

2011 - Elsevier BV | Annals of Emergency Medicine

Revisão Acesso aberto Revisado por pares

Lyndon M. Hill, Fredric Kleinberg,

... noted primarily on motor tasks such as righting. Spyker and associates28Spyker JM Sparber SB Goldberg AM Subtle ... carefully evaluated as a possible cause.45Weiss B Spyker JM Behavioral implications of prenatal and early postnatal ...

Tópico(s): Birth, Development, and Health

1984 - Elsevier BV | Mayo Clinic Proceedings

Artigo Revisado por pares

Daniel A. Spyker, Joan M. Spyker,

Tópico(s): Effects and risks of endocrine disrupting chemicals

1977 - Elsevier BV | Toxicology and Applied Pharmacology

Artigo Acesso aberto Revisado por pares

Heather Payne, J.P.A. Latour,

... This finding stimulated research in this field and Spyker and Fidler (2), Randall and Power (3), and Laqueur (4) repeated this investigation. The series of Spyker and Fidler, in our opinion contained too few ...

Tópico(s): Infant Nutrition and Health

1955 - Oxford University Press | The Journal of Clinical Endocrinology & Metabolism

Artigo Acesso aberto

James F. Winchester, Nikolas B. Harbord,

... hemoperfusion and/or others: 58).2Bronstein A.C. Spyker D.A. Cantilena Jr., L.R. et al. ... Hemoperfusion Could Have Played a Role2Bronstein A.C. Spyker D.A. Cantilena Jr., L.R. et al. ...

Tópico(s): Methemoglobinemia and Tumor Lysis Syndrome

2011 - Elsevier BV | Advances in Chronic Kidney Disease

Artigo Acesso aberto Revisado por pares

David D. Gummin, James B. Mowry, Michael C. Beuhler, Daniel A. Spyker, Laura J. Rivers, Ryan Feldman, Kaitlyn Brown, Nathaniel P. T. Pham, Alvin C. Bronstein, Carol DesLauriers,

Introduction This is the 40th Annual Report of America’s Poison Centers National Poison Data System (NPDS). As of 1 January, 2022, all 55 of the nation’s poison centers (PCs) uploaded case data automatically to NPDS. The upload interval was 4.72 [4.40, 9.27] (median [25%, 75%]) minutes, effectuating a near real-time national exposure and information database and surveillance system.

Tópico(s): Paraquat toxicity studies and treatments

2023 - Taylor & Francis | Clinical Toxicology

Artigo Revisado por pares

David D. Gummin, James B. Mowry, Michael C. Beuhler, Daniel A. Spyker, Laura J. Rivers, Ryan Feldman, Kaitlyn Brown, P. T. Pham Nathaniel, Alvin C. Bronstein, Julie Weber,

This is the 39th Annual Report of America's Poison Centers' National Poison Data System (NPDS). As of 1 January, 2021, all 55 of the nation's poison centers (PCs) uploaded case data automatically to NPDS. The upload interval was 4.87 [4.38, 8.62] (median [25%, 75%]) minutes, effectuating a near real-time national exposure and information database and surveillance system.We analyzed the case data tabulating specific indices from NPDS. The methodology was similar to that of previous years. Where changes ...

Tópico(s): Plant-based Medicinal Research

2022 - Taylor & Francis | Clinical Toxicology

Artigo Revisado por pares

Daniel A. Spyker, Richard C. Dart, Luke Yip, Kate M. Reynolds, Scott Brittain, Mark Yarema,

The introduction of delayed release formulations of acetaminophen (APAP) has created concern about the role of formulation in overdose. We examined the APAP overdose pharmacokinetic (PK) profiles to assess the role of dose, coingestants and formulation: immediate release (IR), extended release (ER), and modified release (MR) on APAP pharmacokinetic measures.We collected by-subject APAP PK data: subject description, timed blood APAP concentrations, dose, and coingestants. We sought both overdose and randomized ...

Tópico(s): Pharmacological Effects and Toxicity Studies

2022 - Taylor & Francis | Clinical Toxicology

Artigo Revisado por pares

David D. Gummin, James B. Mowry, Michael C. Beuhler, Daniel A. Spyker, Alvin C. Bronstein, Laura J. Rivers, Nathaniel P. T. Pham, Julie Weber,

This is the 38th Annual Report of the American Association of Poison Control Centers' (AAPCC) National Poison Data System (NPDS). As of 1 January, 2020, all 55 of the nation's poison centers (PCs) uploaded case data automatically to NPDS. The upload interval was 6.15 [4.60, 8.62] (median [25%, 75%]) minutes, effectuating a near real-time national exposure and information database and surveillance system.We analyzed the case data tabulating specific indices from NPDS. The methodology was similar to that ...

Tópico(s): Plant-based Medicinal Research

2021 - Taylor & Francis | Clinical Toxicology

Artigo Revisado por pares

David D. Gummin, James B. Mowry, Michael C. Beuhler, Daniel A. Spyker, Daniel E. Brooks, Katherine W. Dibert, Laura J. Rivers, Nathaniel P. T. Pham, Mark L. Ryan,

Introduction: This is the 37th Annual Report of the American Association of Poison Control Centers' (AAPCC) National Poison Data System (NPDS). As of 1 January, 2019, all 55 of the nation's poison centers (PCs) uploaded case data automatically to NPDS. The upload interval was 6.52 [6.12, 8.68] (median [25%, 75%]) minutes, creating a near real-time national exposure and information database and surveillance system.Methods: We analyzed the case data tabulating specific indices from NPDS. The methodology ...

Tópico(s): Poisoning and overdose treatments

2020 - Taylor & Francis | Clinical Toxicology

Artigo Acesso aberto Revisado por pares

Nahar Alruwaili, Bachar N. Halimeh, Mohamed A. Al‐Omar, Badria Alhatali, Ismail Ibrahim Sabie, Mohammed Alsaqoub,

... 6(2):147–52. Google Scholar4. Mowry JB, Spyker DA, Brooks DE, Zimmerman A, Schauben JL. "2015 ...

Tópico(s): Healthcare Decision-Making and Restraints

2019 - King Faisal Specialist Hospital and Research Centre | Annals of Saudi Medicine

Artigo Revisado por pares

David D. Gummin, James B. Mowry, Daniel A. Spyker, Daniel E. Brooks, Michael C. Beuhler, Laura J. Rivers, Heba A. Hashem, Mark L. Ryan,

Introduction: This is the 36th Annual Report of the American Association of Poison Control Centers' (AAPCC) National Poison Data System (NPDS). As of 1 January, 2018, 55 of the nation's poison centers (PCs) uploaded case data automatically to NPDS. The upload interval was 7.72 [6.90, 12.0] (median [25%, 75%]) minutes, creating a near real-time national exposure and information database and surveillance system.Methods: We analyzed the case data tabulating specific indices from NPDS. The methodology was ...

Tópico(s): Pesticide Exposure and Toxicity

2019 - Taylor & Francis | Clinical Toxicology

Artigo Revisado por pares

Adam Mutsaers, Jason P. Green, Marco L.A. Sivilotti, Mark Yarema, Dylan Tucker, David W. Johnson, Daniel A. Spyker, Barry H. Rumack,

The Rumack-Matthew nomogram stratifies patients into discrete risk zones following acetaminophen (APAP) overdose. Treatment decisions have traditionally been based on the initial risk zone. "Line-crossing" between zones occurs and is poorly understood. The study objective was to characterize line-crossing behavior in acute APAP overdose patients, especially moving from below to above the nomogram treatment threshold.The study was a secondary analysis of the Canadian Acetaminophen Overdose Study (CAOS) ...

Tópico(s): Liver Disease and Transplantation

2019 - Taylor & Francis | Clinical Toxicology

Carta Acesso aberto Revisado por pares

Kristenbella AYR Lee, Joanna Harnett, Rose Cairns,

... J Pediatr 2005; 164: 520– 522. 5Mowry JB, Spyker DA, Brooks DE, et al. 2015 annual report ...

Tópico(s): Nephrotoxicity and Medicinal Plants

2019 - Wiley | The Medical Journal of Australia

Carta Revisado por pares

Nora D. Volkow, Rubén Baler,

... 1056/NEJMra1402309 CrossrefMedlineGoogle Scholar2. Gummin DD, Mowry JB, Spyker DA, Brooks DE, Osterthaler KM, Banner W. 2017 ...

Tópico(s): Neuroscience of respiration and sleep

2019 - American College of Physicians | Annals of Internal Medicine

Revisão Acesso aberto Revisado por pares

Marc Ghannoum, Robert S. Hoffman, Sophie Gosselin, Thomas D. Nolin, Valéry Lavergne, Darren M. Roberts,

... supportive care.3Gummin D.D. Mowry J.B. Spyker D.A. et al.2016 Annual Report of ...

Tópico(s): Pesticide Exposure and Toxicity

2018 - Elsevier BV | Kidney International

Artigo Acesso aberto Revisado por pares

Mark Yarema, Puja Chopra, Marco L.A. Sivilotti, David W. Johnson, Alberto Nettel‐Aguirre, Benoît Bailey, Charlemaigne Victorino, Sophie Gosselin, Roy Purssell, Margaret Thompson, Daniel A. Spyker, Barry H. Rumack,

Anaphylactoid reactions to intravenous (IV) N-acetylcysteine (NAC) are well-recognized adverse events during treatment for acetaminophen (APAP) poisoning. Uncertainty exists regarding their incidence, severity, risk factors, and management. We sought to determine the incidence, risk factors, and treatment of anaphylactoid reactions to IV NAC in a large, national cohort of patients admitted to hospital for acetaminophen overdose.This retrospective medical record review included all patients initiated ...

Tópico(s): Poisoning and overdose treatments

2018 - Springer Science+Business Media | Journal of Medical Toxicology

Artigo Revisado por pares

David D. Gummin, James B. Mowry, Daniel A. Spyker, Daniel E. Brooks, Krista M. Osterthaler, William Banner,

Introduction: This is the 35th Annual Report of the American Association of Poison Control Centers' (AAPCC) National Poison Data System (NPDS). As of 1 January 2017, 55 of the nation's poison centers (PCs) uploaded case data automatically to NPDS. The upload interval was 8.07 [7.32, 12.65] (median [25%, 75%]) minutes, creating a near real-time national exposure and information database and surveillance system.Methods: We analyzed the case data tabulating specific indices from NPDS. The methodology was ...

Tópico(s): Forensic Toxicology and Drug Analysis

2018 - Taylor & Francis | Clinical Toxicology

Artigo Acesso aberto Revisado por pares

David D. Gummin, James B. Mowry, Daniel A. Spyker, Daniel E. Brooks, Michael O. Fraser, William Banner,

Introduction: This is the 34th Annual Report of the American Association of Poison Control Centers' (AAPCC) National Poison Data System (NPDS). As of 1 January 2016, 55 of the nation's poison centers (PCs) uploaded case data automatically to NPDS. The upload interval was 9.50 [7.33, 14.6] (median [25%, 75%]) min, facilitating a near real-time national exposure and information database and surveillance system.Methods: We analyzed the case data tabulating specific indices from NPDS. The methodology was ...

Tópico(s): Opioid Use Disorder Treatment

2017 - Taylor & Francis | Clinical Toxicology

Artigo Acesso aberto Revisado por pares

J. Craig Nelson, Daniel A. Spyker,

The authors sought to determine the relative morbidity and mortality associated with drugs used to treat depression and to examine specific clinical effects associated with serious outcomes.The National Poison Data System, which receives exposure reports from regional poison centers serving the United States, Puerto Rico, and the District of Columbia, was queried for single drug exposures in individuals 12 years and older during the period 2000-2014. Medications included were antidepressants, atypical ...

Tópico(s): Bipolar Disorder and Treatment

2017 - American Psychiatric Association | American Journal of Psychiatry

Artigo Revisado por pares

James B. Mowry, Daniel A. Spyker, Daniel E. Brooks, A. N. Zimmerman, Jay L. Schauben,

This is the 33rd Annual Report of the American Association of Poison Control Centers' (AAPCC) National Poison Data System (NPDS). As of 1 January 2015, 55 of the nation's poison centers (PCs) uploaded case data automatically to NPDS. The upload interval was 9.52 [7.40, 13.6] (median [25%, 75%]) minutes, creating a near real-time national exposure and information database and surveillance system.We analyzed the case data tabulating specific indices from NPDS. The methodology was similar to that of previous ...

Tópico(s): Plant-based Medicinal Research

2016 - Taylor & Francis | Clinical Toxicology

Artigo Acesso aberto Revisado por pares

James B. Mowry, Daniel A. Spyker, Daniel E. Brooks, Naya McMillan, Jay L. Schauben,

This is the 32nd Annual Report of the American Association of Poison Control Centers' (AAPCC) National Poison Data System (NPDS). As of 1 January 2014, 56 of the nation's poison centers (PCs) uploaded case data automatically to NPDS. The upload interval was 7.82 [7.02, 11.17] (median [25%, 75%]) minutes, creating a near real-time national exposure and information database and surveillance system.We analyzed the case data tabulating specific indices from NPDS. The methodology was similar to that of previous ...

Tópico(s): Pesticide Exposure and Toxicity

2015 - Taylor & Francis | Clinical Toxicology

Artigo Acesso aberto Revisado por pares

Daniel A. Spyker, Robert Riesenberg, James V. Cassella,

Abstract This randomized, double‐blind, placebo‐controlled, parallel‐group study was to determine the pharmacokinetic characteristics, safety, and tolerability of multiple doses of inhaled loxapine aerosol in subjects on a stable, oral, chronic antipsychotic regimen. Loxapine was delivered by means of a unique thermally generated aerosol comprising drug particles of a size designed for deep lung delivery and absorption. Thirty‐two subjects were randomized 1:1:1:1 to receive inhaled loxapine (total ...

Tópico(s): Asthma and respiratory diseases

2015 - Wiley | The Journal of Clinical Pharmacology