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Artigo Acesso aberto Revisado por pares

Stéphane Courtois, Dominique A. Lafontaine, Frédéric P. Lemaigre, Serge Durviaux, Guy Rousseau,

... human growth hormone gene Get access Stéphane J. Courtois, Stéphane J. Courtois Hormone and Metabolic Research Unit, Louvain University Medical ...

Tópico(s): Genetic Syndromes and Imprinting

1990 - Oxford University Press | Nucleic Acids Research

Artigo

Jane Burbank, Frederick Cooper,

Le livre noir du colonialisme joins a now significant body of literature in addressing Europe’s reluctance to come to grips with the importance of colonization to its past. The question concerning this book is not the significance of its subject, but the implications of its approach. Since the 1970s or 1980s in the United States, more recently in France, “colonial studies” has become a field of academic inquiry, crossing disciplinary lines. There are now several alternative conceptions to bri...

Tópico(s): Colonialism, slavery, and trade

2004 - Éditions de l'EHESS | Cahiers d études africaines

Artigo

Robert Legvold, Stéphane Courtois, Nicolas Werth,

... Atrocity Martin Malia * Introduction: The Crimes of Communism Stephane Courtois I. A State against Its People: Violence, Repression, ... Conclusion II. Word Revolution, Civil War, and Terror Stephane Courtois, Jean-Louis Panne, and Remi Kauffer * The Comintern in Action Stephane Courtois and Jean-Louis Panne * The Shadow of the NKVD in Spain Stephane Courtois and Jean-Louis Panne * Communism and Terrorism Remi ... Santamaria * Communism in Afghanistan Sylvain Boulouque Conclusion: Why? Stephane Courtois * Notes * Index * About the Authors

Tópico(s): Historical and Contemporary Political Dynamics

1999 - Council on Foreign Relations | Foreign Affairs

Artigo Revisado por pares

Andrew Scobell,

... and Nicholas Werth, “A State Against Its People,” Stephane Courtois et al., eds., The Black Book of Communism ( ...

Tópico(s): Korean Peninsula Historical and Political Studies

2005 - Taylor & Francis | Asian Security

Artigo Revisado por pares

Ronald Aronson,

Books reviewed in this article: Stéphane Courtois et al., The Black Book of Communism: Crimes, Terror, Repression François Furet, The Passing of an Illusion: The Idea of Communism ...

Tópico(s): Italian Fascism and Post-war Society

2003 - Wiley | History and Theory

Artigo Revisado por pares

David Galloway, Stéphane Courtois, Jonathan Murphy, Mark Kramer,

Tópico(s): Communism, Protests, Social Movements

2001 - American Association of Teachers of Slavic and East European Languages | The Slavic and East European Journal

Artigo Revisado por pares

Nathalie Zammatteo, Laurent Jeanmart, Sandrine Hamels, Stéphane Courtois, Pierre Louette, Laszlo Hevesi, José Remacle,

DNA microarray is a powerful tool allowing simultaneous detection of many different target molecules present in a sample. The efficiency of the array depends mainly on the sequence of the capture probes and the way they are attached to the support. The coupling procedure must be quick, covalent, and reproducible in order to be compatible with automatic spotting devices dispensing tiny drops of liquids on the surface. We compared several coupling strategies currently used to covalently graft DNA ...

Tópico(s): Advanced Biosensing Techniques and Applications

2000 - Elsevier BV | Analytical Biochemistry

Artigo Acesso aberto Revisado por pares

Rudolf Walther,

... zum einen das Vor- und Nachwort des Herausgebers Stephane Courtois, das bisher im Mittelpunkt der Debatte stand, in ...

1999 - Verlag Westfälisches Dampfboot | PROKLA Zeitschrift für kritische Sozialwissenschaft

Artigo Acesso aberto Revisado por pares

Annelies Vantieghem, Zerihun Assefa, Peter Vandenabeele, Wim Declercq, Stéphane Courtois, Jackie R. Vandenheede, Wilfried Merlevede, Peter de Witte, Patrizia Agostinis,

Here we report that photoactivated hypericin can induce either apoptosis or necrosis in HeLa cells. Under apoptotic conditions the cleavage of poly(ADP‐ribose) polymerase (PARP) into the 85‐kDa product is blocked by the caspase inhibitors benzyloxycarbonyl‐Val‐Ala‐Asp‐fluoromethylketone (z‐VAD‐fmk) and benzyloxycarbonyl‐Asp‐Glu‐Val‐Asp‐fluoromethylketone (z‐DEVD‐fmk). Both inhibitors protect cells from apoptosis but cannot prevent hypericin‐induced necrosis. Conversely, HeLa cells overexpressing the ...

Tópico(s): Ocular Infections and Treatments

1998 - Wiley | FEBS Letters

Artigo Revisado por pares

Stéphane Courtois, Siegfried Segaert, H. Degreef, R. Bouillon, Marjan Garmyn,

Keratinocytes not only produce vitamin D3in response to ultraviolet B light (UVB) and convert 25-hydroxyvitamin D3to 1α,25-dihydroxyvitamin D3(1,25(OH)2D) but also possess the vitamin D receptor (VDR) and respond to 1,25(OH)2D. We characterized the regulation of the expression of the VDR gene in primary human keratinocytes following UVB irradiation. We report a marked dose-dependent down-regulation of the VDR mRNA and protein within a few hours after irradiation. This occurs independently ofde novoprotein ...

Tópico(s): Skin Protection and Aging

1998 - Elsevier BV | Biochemical and Biophysical Research Communications

Artigo Revisado por pares

Stéphane Courtois, Craig D. Woodworth, H. Degreef, Marjan Garmyn,

Wild-type p53 (wt-p53) negatively controls cell cycle progression after cellular stress mediating either a temporary growth arrest or apoptosis, depending on the cell type and nature of the cellular stress. The aberrant proliferation which is characteristic of tumor cells may be suppressed by exogenous wt-p53 and appears to depend strongly on the level of reexpression. We performed retroviral-mediated gene transfer of wt-p53 into a human squamous cell carcinoma cell line from the head and neck region ( ...

Tópico(s): Cancer, Hypoxia, and Metabolism

1997 - Elsevier BV | Experimental Cell Research

Artigo Acesso aberto Revisado por pares

Maria Veiga‐da‐Cunha, Stéphane Courtois, Alain Michel, Eric Gosselain, Emile Van Schaftingen,

To delineate the regions of liver glucokinase that are involved in the binding of its regulatory protein and have therefore been conserved throughout evolution, we have cloned the cDNA of the Xenopus laevis enzyme. It contains an open reading frame of 1374 nucleotides and encodes a protein of 458 amino acids, which displays 78 and 79% overall identity to rat and human liver glucokinases, respectively. The conserved regions are predicted to be present mainly in the small domain and the hinge region ...

Tópico(s): Endoplasmic Reticulum Stress and Disease

1996 - Elsevier BV | Journal of Biological Chemistry

Artigo Revisado por pares

Charles De Smet, Stéphane Courtois, Isabella Faraoni, Christophe Lurquin, Jean‐Pierre Szikora, Olivier De Backer, Thierry Boon,

Tópico(s): Glycosylation and Glycoproteins Research

1995 - Springer Science+Business Media | Immunogenetics

Artigo Acesso aberto Revisado por pares

Stéphane Courtois, Dominique A. Lafontaine, Guy Rousseau,

Transcription of the human growth hormone (hGH) gene depends on cis-acting elements contained within 300 base pairs of its 5'-flanking sequence. An earlier in vitro study of the transcriptional activity of this 5'-flanking region suggested that transcription can start upstream from position +1. We have investigated this phenomenon by cell-free transcription and transient transfection of chimeric constructs in cultured pituitary cells and in HeLa cells and by analysis of RNA from human pituitary glands ...

Tópico(s): RNA Research and Splicing

1992 - Elsevier BV | Journal of Biological Chemistry

Artigo Acesso aberto Revisado por pares

Frédéric P. Lemaigre, Dominique A. Lafontaine, Stéphane Courtois, S M Durviaux, Guy Rousseau,

DNase I footprinting experiments showed that binding activities of Sp1 and of GHF-1 to its distal site on the human growth hormone gene promoter are mutually exclusive. The kinetics of GHF-1 binding were indicative of positive cooperativity. The Sp1 site did not affect promoter activity in cell-free transcription. Still, Sp1 could compensate partially for the decreased stimulation of transcription seen at low GHF-1 concentrations.

Tópico(s): RNA modifications and cancer

1990 - Taylor & Francis | Molecular and Cellular Biology

Artigo Acesso aberto Revisado por pares

Frédéric P. Lemaigre, Dominique A. Lafontaine, Stéphane Courtois, Serge Durviaux, Guy Rousseau,

DNase I footprinting experiments showed that binding activities of Sp1 and of GHF-1 to its distal site on the human growth hormone gene promoter are mutually exclusive. The kinetics of GHF-1 binding were indicative of positive cooperativity. The Sp1 site did not affect promoter activity in cell-free transcription. Still, Sp1 could compensate partially for the decreased stimulation of transcription seen at low GHF-1 concentrations.

Tópico(s): Pancreatic function and diabetes

1990 - Taylor & Francis | Molecular and Cellular Biology

Artigo

Frédéric P. Lemaigre, Stéphane Courtois, Dominique A. Lafontaine, Guy Rousseau,

Expression of the human‐growth‐hormone gene is restricted to pituitary somatotrophs. Two protein‐DNA complexes that are specific to the pituitary, and two that are not, had been demonstrated in vitro on the promoter of this gene. The two pituitary‐specific footprints had been ascribed to a single protein called growth hormone factor 1. We have now characterized the factors responsible for the two other footprints by means of deoxyribonuclease‐I protection and gel‐retardation experiments. The first ...

Tópico(s): RNA Research and Splicing

1989 - Wiley | European Journal of Biochemistry

Artigo Revisado por pares

Siegfried Segaert, Stéphane Courtois, Marjan Garmyn, H. Degreef, Roger Bouillon,

Apigenin, a flavonoid with chemopreventive properties, induces cellular growth arrest, with concomitant inhibition of intracellular signaling cascades and decreased proto-oncogene expression. We report that apigenin potently inhibited vitamin D receptor (VDR) mRNA and protein expression in human keratinocytes without changes in VDR mRNA half-life. Concurrently, downregulation of retinoid X receptor α, a dramatic loss of c-myc mRNA, and upregulation of p21WAF1 took place. Furthermore, a nearly complete ...

Tópico(s): Vitamin D Research Studies

2000 - Elsevier BV | Biochemical and Biophysical Research Communications

Artigo

Frédéric P. Lemaigre, Stéphane Courtois, Serge Durviaux, Christine J. Egan, Dominique A. Lafontaine, Guy G. Rousseau,

The expression of the human growth hormone (hGH) gene is regulated by several transcription factors. Basal level transcription factors include TATA box-binding proteins, Sp1, USF and CTF/NF-1. The hGH gene is expressed only in pituitary somatotrophs, and the pituitary-specific GHF-1/Pit-1 protein is a potent transcriptional stimulator. Glucocorticoid and thyroid hormones, insulin, and GHRH which acts via cAMP, also control hGH gene transcription via trans-acting factors some of which are the hormone ...

Tópico(s): Adipose Tissue and Metabolism

1989 - Pergamon Press | Journal of Steroid Biochemistry

Artigo

Richard J. Golsan,

... during the bombing of Kosovo, and the historian Stephane Courtois's revisionist comparison of Nazi and Communist crimes ...

Tópico(s): Historical and Political Studies

2006 - Association of College and Research Libraries | Choice Reviews Online

Artigo Acesso aberto Revisado por pares

André Lejeune, Stéphane Courtois, Charles Colson,

Several enzymatic properties of an endoglucanase produced in Escherichia coli by a gene from Pseudomonas fluorescens subsp. cellulosa were investigated. Gel filtration revealed a single peak of M r 36,000 with endoglucanase activity. The pH optimum of the enzyme was 7.0. Carboxymethyl cellulose and barley β-glucan (mixed β-1,3 and 1,4 linkages) were good substrates, but not laminarin (β-1,3 linkages), amylose, filter paper, microcrystalline cellulose (Avicel), or cellotriose. The mode of action was ...

Tópico(s): Polysaccharides and Plant Cell Walls

1988 - American Society for Microbiology | Applied and Environmental Microbiology

Artigo

Aurélien Aramini, Florian Gulli,

... propose une lecture critique de la biographie que Stéphane Courtois a consacrée à Lénine en 2017 : Lénine, l’ ... la fois historique et philosophique. La lecture de Stéphane Courtois est tributaire de sources réduites en nombre et ...

Tópico(s): French Urban and Social Studies

2024 - Fondation Gabriel-Péri | La Pensée

Artigo Acesso aberto Revisado por pares

Sophie Dupuis‐Girod, Nadège Corradini, S. Hadj‐Rabia, Jean‐Christophe Fournet, Laurence Faivre, Françoise Le Deist, Philippe Durand, Rainer Döffinger, Asma Smahi, Alain Israël, Gilles Courtois, Nicole Brousse, Stéphane Blanche, Arnold Münnich, Alain Fischer, Jean‐Laurent Casanova, Christine Bodemer,

A child with X-linked osteopetrosis, lymphedema, anhidrotic ectodermal dysplasia, and immunodeficiency (OL-EDA-ID) was recently reported. We report the clinical features of a second boy with this novel syndrome and his mother, who presented with signs of incontinentia pigmenti (IP). The child had mild osteopetrosis without neurosensory complications, unilateral lymphedema of the left leg, and characteristic features of anhidrotic ectodermal dysplasia with sparse hair, facial dysmorphy, delayed eruption ...

Tópico(s): Skin and Cellular Biology Research

2002 - American Academy of Pediatrics | PEDIATRICS

Artigo Revisado por pares

Élodie Béthoux, Annette Jobert,

... and Society, Sage Publications, London, 2001.Dominique LABBE, Stephane COURTOIS (Eds.), Regards sur la crise du syndica...

Tópico(s): Social Policy and Reform Studies

2004 - Elsevier BV | Sociologie du Travail

Artigo

Laurent Gervereau,

... 1939. Posterite de 1789, sous la direction de Stephane Courtois. pp. 40-41.

Tópico(s): Translation Studies and Practices

1989 - La contemporaine | Matériaux pour l’histoire de notre temps