Hai‐Qiang Mai, W. Stratford May, Fengqin Gao, Zhaohui Jin, Xingming Deng,
... or presence of various concentrations of PD98059 or Stauro for 30 min. Phosphorylated ERK1/2 and total ... Figure ViewerDownload Hi-res image Download (PPT) Staurosporine (Stauro) is a potent PKC inhibitor, whereas PD98059 can ... Scopus (3241) Google Scholar). Because either PD98059 or Stauro can inhibit nicotine-induced ERK1/2 activation (Fig. ... with nicotine in the absence or presence of Stauro or PD98059 or their combination. The results show that Stauro or PD98059 potently inhibit nicotine-induced Bcl2 phosphorylation ( ...
Tópico(s): Bioactive Compounds and Antitumor Agents
2003 - Elsevier BV | Journal of Biological Chemistry
Lisa A. Madge, M. Rocı́o Sierra-Honigmann, Jordan S. Pober,
... PBS, phosphate-buffered saline; RIP, receptor-interacting protein; stauro, staurosporine; Tapi, TNF-α proteinase inhibitor; TNFR1 and ... acid, short chain ceramide (C6-ceramide), and staurosporine (stauro) have been reported to inhibit TNF-mediated activation ... Enzyme Systems Products (Dublin, CA). SB203580, C6-ceramide, stauro, and yVADcmk were purchased from Calbiochem. R32W TNF ... EC with ATK, C6-ceramide, sodium salicylate, and stauro. EC were treated as described, harvested by collagenase ( ... the cytosolic phospholipase A2inhibitor ATK, the kinase inhibitor stauro, the anti-inflammatory agent sodium salicylate, and the ...
Tópico(s): Immune Response and Inflammation
1999 - Elsevier BV | Journal of Biological Chemistry
... one of three treatments: polymyxin B (PolyB), staurosporine (Stauro), and 8-sulfophenylthephylline (SPT). In the second series ... after repetitive PC with or without PolyB or Stauro treatment. Then, myocardial tissue in the ischemic region ... PolyB (%IS/AR=43.9±2.7) and Stauro (%IS/AR=31.5±3.2). Although the ... its Ki for PKC, this agent and also Stauro failed to abolish the protection by repetitive PC (% ... non-preconditioned hearts were not modified by PolyB, Stauro, or SPT. The ratio of membrane fraction PKC ... PKC was inhibited in hearts given PolyB and Stauro. Conclusions: In contrast to single PC, repetitive PC ...
Tópico(s): Anesthesia and Neurotoxicity Research
1998 - Oxford University Press | Cardiovascular Research
Xingming Deng, Peter P. Ruvolo, Boyd K. Carr, W. Stratford May,
... apoptosis induced by the potent PKC inhibitor, staurosporine (stauro). High concentrations of stauro of up to 1 μM only partially inhibit ... vitro . These data indicate a role for a stauro-resistant Bcl2 kinase (SRK). We show that aurintricarboxylic ... Bcl2 phosphorylation, whereas the combination of PD98059 and stauro completely blocks phosphorylation and synergistically enhances apoptosis. p44MAPK/ ... directly phosphorylate Bcl2 on Ser-70 in a stauro-resistant manner both in vitro and in vivo . ... novel capacity, may explain how Bcl2 can suppress stauro-induced apoptosis. In addition, although the mechanism of ...
Tópico(s): Melanoma and MAPK Pathways
2000 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Jun Sakamoto, Tetsuji Miura, Mahiko Goto, Osamu Iimura,
... adenosine (PIA), 50 micrograms.kg-1 of staurosporine (Stauro), 2.5 mg.kg-1 of polymyxin B (PolyB), and a combination of PIA and either Stauro or PolyB. Infarct size and the area at ... and without pretreatment using the same doses of Stauro and PolyB as those in the first series ... 05. However, %IS/AR in the groups given Stauro [35.0(4.2)%], PolyB [37.9(3.2)%], PIA plus Stauro [34.9(3.9)%], and PIA plus PolyB [ ... PMA was not detected in rabbits pretreated with Stauro or PolyB, suggesting that the doses of the ...
Tópico(s): Cardiac Imaging and Diagnostics
1995 - Oxford University Press | Cardiovascular Research
Darryle D. Schoepp, Bryan G. Johnson,
... partial inhibition could be attained. Preincubation with staurosporine (STAURO) (10−5M) or 1-(5-isoquinolinesulfonyl)-2-methyl- ... phosphoinositide hydrolysis was reversed by co-addition of STAURO or H-7. In the case of IBO + STAURO, this reversal was to the potentiated level observed with STAURO alone. Enhanced agonist stimulation and reversal of PDB inhibition were also produced by STAURO when [3H]-phosphoinositide hydrolysis was stimulated by either ...
Tópico(s): Drug Transport and Resistance Mechanisms
1988 - Elsevier BV | Biochemical Pharmacology
... recognized by the possession of cribrate areolae, a stauros that is usually narrower than the fascia, many ... these than to other naviculoid genera with a stauros, i.e. Stauroneis, Staurophora Mereschkowsky, Meuniera Silva and Haslea Simonsen. The stauros is a feature that probably arose a number ... briefly discussed. Keywords: Craspedostauros marine diatoms Stauroneis Stauronella stauros taxonomy
Tópico(s): Paleontology and Stratigraphy of Fossils
1999 - Taylor & Francis | European Journal of Phycology
Matt P. Ashworth, Christopher S. Lobban, Andrzej Witkowski, Edward C. Theriot, Meeshal J. Sabir, Mohammad N. Baeshen, Nahid H. Hajarah, Nabih A. Baeshen, Jamal S. M. Sabir, Robert K. Jansen,
Several lineages of raphe-bearing diatoms possess a "stauros," which is a transverse, usually thickened area free ... diatoms, but we have noticed similarities beyond the stauros between two marine genera-Craspedostauros and Staurotropis-in ...
Tópico(s): Genomics and Phylogenetic Studies
2016 - Elsevier BV | Protist
Eileen J. Cox, David J. Williams,
... to members of the Mastogloiaceae or to other stauros-bearing diatoms. The analysis also tested, and confirmed, the hypothesis that the stauros, as recognized by light microscopy, is a homoplastic ...
Tópico(s): Fish biology, ecology, and behavior
2000 - Taylor & Francis | European Journal of Phycology
Byron D. Ford, Michael T. Ivy, C Mtshali, James G. Townsel,
... 3H]choline cotransport. Conversely, the PKC inhibitors, staurosporine (STAURO) and polymyxin B (PMB), each increased [3H]choline ... transport. Both the PMA induced decrease and the STAURO induced increase in [3H]choline cotransport were paralleled ... binding. The enhancement of [3H]choline cotransport by STAURO and antecedent 120 mM KCl treatment were additive. ...
Tópico(s): Protein Kinase Regulation and GTPase Signaling
1999 - Elsevier BV | Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology
Francesco G. Salerno, Mara S. Ludwig,
... with the calmodulin inhibitor calmidazolium (Cmz) or staurosporine (Stauro), a protein kinase C inhibitor. Elastance (E) and ... unloaded shortening velocity measured during electrical field stimulation; Stauro decreased the T, E, and R response to ... parenchymal strips, Cmz decreased the η response, whereas Stauro had no effect. These results suggest that modifications ...
Tópico(s): Advanced Sensor and Energy Harvesting Materials
1998 - American Physiological Society | Journal of Applied Physiology
Riccardo Trentin, Emanuela Moschin, André D. Lopes, Stefano Schiaparelli, Luísa Custódio, Isabella Moro,
... two “fore-and-aft” chloroplasts and a narrow “stauros”. This classification is congruent with the molecular phylogeny ... and of others raphe-bearing diatoms with a “stauros” is particularly challenging and their phylogeny is still ...
Tópico(s): Genomics and Phylogenetic Studies
2022 - Multidisciplinary Digital Publishing Institute | Journal of Marine Science and Engineering
Ewa Górecka, Matt P. Ashworth, Н. А. Давидович, Olga I. Davidovich, Przemysław Dąbek, Jamal S. M. Sabir, Andrzej Witkowski,
... frustules of Schizostauron are characterized by a bifid stauros on the raphe‐bearing valve and intricate areolate ... features of Schizostauron and Astartiella , such as the stauros, fistula, and coaxial internal proximal raphe endings, are ...
Tópico(s): Marine and coastal ecosystems
2021 - Wiley | Journal of Phycology
Maxim Kulikovskiy, Anton Glushchenko, Irina Kuznetsova, С. И. Генкал, John Patrick Kociolek,
... an asymmetric axial area that expands into a stauros to form the central area, similar to those ... and Gogorevia. Based on the presence of a stauros, uniseriate striae, and the same type of pore ...
Tópico(s): Aquatic Invertebrate Ecology and Behavior
2020 - Taylor & Francis | Phycologia
Neha Wadmare, Surajit Roy, John Patrick Kociolek, Balasubramanian Karthick,
... rounded apices, radiate striae, and a H-shaped stauros. S. lepchae has broadly elliptical to lanceolate valves ... radiate striae, and a characteristic bow-tie shaped stauros. These are the first two diatom species described ...
Tópico(s): Genomics and Phylogenetic Studies
2019 - Société botanique de France | Botany Letters
Sophia E. Schiza, Εmmanuel Simantirakis, Izolde Bouloukaki, Charalampos Mermigkis, Eleftherios M. Kallergis, Stavros I. Chrysostomakis, Dimitrios Arfanakis, Νikolaos Tzanakis, Panos Vardas, Nikolaos M. Siafakas,
... D., Ph.D., Eleftherios M. Kallergis, M.D., Stauros Chrysostomakis, M.D., Dimitrios Arfanakis, M.D., Nikolaos ... of Cardiology, University General Hospital, Heraklion, Crete, Greece , Stauros Chrysostomakis, M.D. Department of Cardiology, University General ...
Tópico(s): Cardiovascular Syncope and Autonomic Disorders
2012 - American Academy of Sleep Medicine | Journal of Clinical Sleep Medicine
Ankathrin Förster, Tanja Emmler, Stephanie Schwalm, Mahsa Ebadi, Dagmar Meyer zu Heringdorf, Barbara Nieuwenhuis, Burkhard Kleuser, Andrea Huwiler, Josef Pfeilschifter,
... for 16 h with either vehicle (Co), staurosporine (stauro, 30 nm), staurosporine (30 nm) plus dexamethasone (300 nm) (stauro+dex), or dexamethasone alone (300 nm). Cells were ...
Tópico(s): Endoplasmic Reticulum Stress and Disease
2010 - Elsevier BV | Kidney International
Zafiria M. Metafratzi, Miltos Vassiliou, George C. Maglaras, Froso G. Katzioti, Stauros H. Constantopoulos, Afroditi Katsaraki, Stauros C. Efremidis,
The purpose of our study was to investigate the relation between the pulmonary artery obstruction index assessed with helical CT and impairment in blood gases in patients with acute pulmonary embolism.Helical CT pulmonary angiography was performed in 78 patients who were suspected of having acute pulmonary embolism and selected as being free of underlying cardiopulmonary disease. Findings consistent with acute pulmonary embolism were observed in 34 patients. The severity was assessed by the pulmonary ...
Tópico(s): Radiation Dose and Imaging
2005 - American Roentgen Ray Society | American Journal of Roentgenology
... Coptic Papyrus" (editio princeps 1900). The Old Nubian "Stauros-Text" (known also from an as yet unpublished ...
Tópico(s): Archaeology and Historical Studies
2003 - Brepols | Apocrypha
A. K. S. K. Prasad, Kimberly A. Riddle, James A. Nienow,
... H-shaped plastids and by the absence of stauros and associated pores. Climaconeis colemaniae closely resembles C. ... arrangement of the striae, polar mantle slits, central stauros, and two isolated pores in the central area; ...
Tópico(s): Environmental Monitoring and Data Management
2000 - Taylor & Francis | Phycologia
Gábor Szalai, Rajeshwari Krishnamurthy, György Hajnóczky,
... cell preparation (n = 5). (D) Effect of staurosporine (Stauro, 1 μM) on Ca2+-induced mitochondrial depolarization and ... naive (black), C2-pretreated (180 s, purple) and Stauro-pretreated (60 min, red) cells supplemented with malate ( ...
Tópico(s): Mitochondrial Function and Pathology
1999 - Springer Nature | The EMBO Journal
Haiyan Liu, Vasudeo Badarinarayana, Deborah C. Audino, Juri Rappsilber, Matthias Mann, Clyde L. Denis,
... C YD 1 M sorbitol Mg2+ 750 mM Stauro 1 mg/ml 3 AT 20 mM wt ... 8 mM caffeine, 1 mg/ml of staurosporine (stauro), 750 mM MgCl2 or 1 M sorbitol as ...
Tópico(s): Advanced Proteomics Techniques and Applications
1998 - Springer Nature | The EMBO Journal
... 37°C 37°C + sorb. Gly 37°C Stauro Stauro + sorb. Caffeine LiCl 188 wt + + + + + + + + + 188-1 ccr4 − + ...
Tópico(s): DNA Repair Mechanisms
1997 - Springer Nature | The EMBO Journal
Danuta M. Rzymkiewicz, Toshifumi Tetsuka, Dorit Daphna-Iken, Sunil Kumar Srivastava, Aubrey R. Morrison,
... IL-1β, 100 nM PMA, 100 nM staurosporine (Stauro), and 5 µM calphostin C (Cal C) were ... not inhibited at 10 and 100 nM staurosporine (Stauro); B, similar experiments showing dose-dependent inhibition of ...
Tópico(s): Cell Adhesion Molecules Research
1996 - Elsevier BV | Journal of Biological Chemistry
... parallel the trends in the K. amsdeni–K. stauros–K. variabilis lineage and resulted in the divergence of Kockelella cf. K. stauros Bischoff, 1986, from the main lineage in the ...
Tópico(s): Geochemistry and Geologic Mapping
1994 - Cambridge University Press | Journal of Paleontology
Dale A. Pelligrino, Heidi M. Koenig, Qiong Wang, Ronald F. Albrecht,
... In the presence of the PKC inhibitor, staurosporine (STAURO), the Ach, ADP, and ISO responses were, largely restored and the SNP response was unaffected. STAURO produced no changes in Ach, ADP, ISO, or ...
Tópico(s): Apelin-related biomedical research
1994 - Lippincott Williams & Wilkins | Neuroreport
Stauros Meropoulis, C.A. Aggelopoulos,
The main scope of this study was the direct comparison of gas-liquid DBD and plasma microbubbles (PMB) driven by high voltage nanopulses in terms of pollutant destruction mechanisms, plasma-activated water composition and cost-effectiveness. The comparison between gas-liquid DBD and PMB was evaluated in terms of water physicochemical properties and plasma species concentrations, performance towards the degradation of dyes with different structure, energy yield and electrical energy per order (EEO) ...
Tópico(s): Advanced oxidation water treatment
2023 - Elsevier BV | Journal of environmental chemical engineering
Stauros Meropoulis, Stefania Giannoulia, Spyros S. Skandalis, Gerasimos Rassias, C.A. Aggelopoulos,
Cephalosporins is a class of β-lactam antibiotics being widely used and often released uncontrollably in aquatic systems thus resulting in serious environmental contamination.In this work, we investigated for the first-time the degradation of cephalexin (CPX) and cefazolin (CFZ) by nanosecond-pulsed cold atmospheric plasma (NSP-CAP) using a multi-pin-to-liquid corona reactor, proposing special degradation pathways of both cephalosporins and assessing their residual toxicities.Increasing pulse voltage ...
Tópico(s): Analytical chemistry methods development
2022 - Elsevier BV | Separation and Purification Technology
C.A. Aggelopoulos, Anna-Maria Christodoulou, Myrsini Tachliabouri, Stauros Meropoulis, Maria‐Elpida Christopoulou, Theodoros Karalis, Athanasios Chatzopoulos, Spyros S. Skandalis,
Breast cancer exists in multiple subtypes some of which still lack a targeted and effective therapy. Cold atmospheric plasma (CAP) has been proposed as an emerging anti-cancer treatment modality. In this study, we investigated the effects of direct and indirect CAP treatment driven by the advantageous nanosecond pulsed discharge on breast cancer cells of different malignant phenotypes and estrogen receptor (ER) status, a major factor in the prognosis and therapeutic management of breast cancer. The ...
Tópico(s): Plasma Applications and Diagnostics
2022 - Frontiers Media | Frontiers in Oncology
Stauros Meropoulis, Gerasimos Rassias, Vlasoula Bekiari, C.A. Aggelopoulos,
Cold atmospheric plasma (CAP) is regarded as a highly competitive advanced oxidation process towards the removal of organic pollutants from wastewater. Nevertheless, the differences in plasma-induced degradation mechanisms and kinetics are poorly understood and affect their efficient remediation. In this work, nanosecond pulsed dielectric barrier discharge plasma (NSP-DBD) was employed to investigate the degradation/mineralization kinetics of five popular dyes (Orange II, Methylene Blue, Methyl Violet, ...
Tópico(s): Surface Modification and Superhydrophobicity
2021 - Elsevier BV | Separation and Purification Technology