Md Abdullah Al Mamun, Shownak Saha, Jianfeng Li, Ruhina Binta A Ghani, Syed Mahfuz Al Hasan, Ayesha Begum,
... food insecurity in a coastal region of Bangladesh, Suborno Char (one of Noakhali District's coastal neighbourhoods) ... survey with multistage sampling technique was employed, and Suborno Char of Noakhlai district was purposely sampled of ...
Tópico(s): Breastfeeding Practices and Influences
2022 - SAGE Publishing | INQUIRY The Journal of Health Care Organization Provision and Financing
Suborno M. Ghosh, D.W. Bethune, I. Hardy, John Kneeshaw, R.D. Latimer, A. Oduro,
Summary The quality of donor organs will determine the quality of life for the recipient and the importance of optimal management of the multi‐organ donor is that the organs may benefit up to five, critically ill, patients. The basic principle is to maintain sufficient preload to minimise the need for inotropic support and it is recommended that all multiple organ donors should have central venous and arterial pressure monitoring in addition to adequate venous access. The importance of the choice ...
Tópico(s): Transplantation: Methods and Outcomes
1990 - Wiley | Anaesthesia
Reshma S. Baliga, Alexandra Milsom, Suborno M. Ghosh, Sarah L. Trinder, Raymond J. MacAllister, Amrita Ahluwalia, Adrian J. Hobbs,
Background— Pulmonary hypertension (PH) is a multifactorial disease characterized by increased pulmonary vascular resistance and right ventricular failure; morbidity and mortality remain unacceptably high. Loss of nitric oxide (NO) bioactivity is thought to contribute to the pathogenesis of PH, and agents that augment pulmonary NO signaling are clinically effective in the disease. Inorganic nitrate (NO 3 − ) and nitrite (NO 2 − ) elicit a reduction in systemic blood pressure in healthy individuals; this effect ...
Tópico(s): Renin-Angiotensin System Studies
2012 - Lippincott Williams & Wilkins | Circulation
Manpreet Bahra, Vikas Kapil, Vanessa Pearl, Suborno M. Ghosh, Amrita Ahluwalia,
Ingestion of inorganic nitrate elevates blood and tissue levels of nitrite via bioconversion in the entero-salivary circulation. Nitrite is converted to NO in the circulation, and it is this phenomenon that is thought to underlie the beneficial effects of inorganic nitrate in humans. Our previous studies have demonstrated that oral ingestion of inorganic nitrate decreases blood pressure and inhibits the transient endothelial dysfunction caused by ischaemia–reperfusion injury in healthy volunteers. ...
Tópico(s): Blood Pressure and Hypertension Studies
2012 - Elsevier BV | Nitric Oxide
Suborno M. Ghosh, Vikas Kapil, Isabel Fuentes‐Calvo, Kristen J. Bubb, Vanessa Pearl, Alexandra Milsom, Rayomand S. Khambata, Sheiva Maleki-Toyserkani, Mubeen Yousuf, Nigel Benjamin, David J. Webb, Mark J. Caulfield, Adrian J. Hobbs, Amrita Ahluwalia,
Elevation of circulating nitrite (NO2(-)) levels causes vasodilatation and lowers blood pressure in healthy volunteers. Whether these effects and the underpinning mechanisms persist in hypertension is unknown. Therefore, we investigated the consequences of systemic nitrite elevation in spontaneously hypertensive rats and conducted proof-of-principle studies in patients. Nitrite caused dose-dependent blood pressure-lowering that was profoundly enhanced in spontaneously hypertensive rats versus normotensive ...
Tópico(s): Renin-Angiotensin System Studies
2013 - Lippincott Williams & Wilkins | Hypertension
Shanti Velmurugan, Vikas Kapil, Suborno M. Ghosh, Sheridan Davies, Andrew McKnight, Zainab Aboud, Rayomand S. Khambata, David J. Webb, Alastair W. Poole, Amrita Ahluwalia,
Ingestion of vegetables rich in inorganic nitrate has emerged as an effective method, via the formation of a nitrite intermediate, for acutely elevating vascular NO levels. As such a number of beneficial effects of dietary nitrate ingestion have been demonstrated including the suggestion that platelet reactivity is reduced. In this study we investigated whether inorganic nitrate supplementation might also reduce platelet reactivity in healthy volunteers and have determined the mechanisms involved ...
Tópico(s): Cardiovascular Syncope and Autonomic Disorders
2013 - Elsevier BV | Free Radical Biology and Medicine
Shanti Velmurugan, Jasmine Gan, Krishnaraj S. Rathod, Rayomand S. Khambata, Suborno M. Ghosh, Amy Hartley, Sven van Eijl, Virág Sági‐Kiss, Tahseen A Chowdhury, Michael A. Curtis, Gunter G. C. Kuhnle, William G. Wade, Amrita Ahluwalia,
Background: The beneficial cardiovascular effects of vegetables may be underpinned by their high inorganic nitrate content. Objective: We sought to examine the effects of a 6-wk once-daily intake of dietary nitrate (nitrate-rich beetroot juice) compared with placebo intake (nitrate-depleted beetroot juice) on vascular and platelet function in untreated hypercholesterolemics. Design: A total of 69 subjects were recruited in this randomized, double-blind, placebo-controlled parallel study. The primary ...
Tópico(s): Cardiovascular Health and Disease Prevention
2015 - Elsevier BV | American Journal of Clinical Nutrition
Rayomand S. Khambata, Suborno M. Ghosh, Amrita Ahluwalia,
In contrast to nitric oxide (NO), which has well-established, important effects in regulation of cardiovascular homeostasis, its oxidative metabolite nitrite has, until recently, been considered to be of minor functional significance.However, this view of nitrite has been radically revised over the past 10 years with evidence now supporting a critical role for this anion as a storage form of NO.Importantly, while hypoxia and acidosis have been shown to play a pivotal role in the generation of nitrite ...
Tópico(s): Aldose Reductase and Taurine
2015 - Mary Ann Liebert, Inc. | Antioxidants and Redox Signaling
Rayomand S. Khambata, Suborno M. Ghosh, Krishnaraj S. Rathod, Tharssana Thevathasan, Federica Filomena, Qingzhong Xiao, Amrita Ahluwalia,
Significance Reduced bioavailable nitric oxide generated within the vascular wall is a key pathogenic mechanism involved in the formation and rupture of an atheromatous plaque, the latter leading to myocardial infarction or stroke. We show that inorganic nitrate supplementation through delivery of nitric oxide reduces systemic leukocyte rolling and adherence, circulating neutrophil numbers, and monocyte activation through direct repression of neutrophil activation and up-regulation of interleukin- ...
Tópico(s): Neuroinflammation and Neurodegeneration Mechanisms
2017 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Suborno Jati, Suman Kundu, Arijit Chakraborty, Sushil K. Mahata, Victor Nizet, Malini Sen,
Bacterial pathogens are associated with severe infections (e.g. sepsis) and exacerbation of debilitating conditions such as chronic obstructive pulmonary disease (COPD). The interactions of bacterial pathogens with macrophages, a key component of innate immunity and host defense, are not clearly understood and continue to be intensively studied. Having previously demonstrated a role of Wnt5A signaling in phagocytosis, we proceeded to decipher the connection of Wnt5A signaling with infection by pathogenic ...
Tópico(s): Adenosine and Purinergic Signaling
2018 - Frontiers Media | Frontiers in Immunology
Suborno Jati, Tresa Rani Sarraf, Debdut Naskar, Malini Sen,
Wnt ligands interact with the transmembrane cell surface receptors Frizzled and ROR / RYK to initiate complex signaling cascades that are crucial for cell physiology and the proper functioning of the immune system. Wnt signaling is instrumental in maintaining immune surveillance and during infections by pathogenic microbes helps mount host resistance to infection. Some pathogens, however, utilize Wnt signaling to build a niche for their survival. The goal of this review is to summarize current and ...
Tópico(s): Toxin Mechanisms and Immunotoxins
2019 - Frontiers Media | Frontiers in Immunology
Suborno Jati, Soham Sengupta, Malini Sen,
Wnt5A signaling facilitates the killing of several bacterial pathogens, but not the non-pathogen E. coli DH5α. The basis of such pathogen vs. non-pathogen distinction is unclear. Accordingly, we analyzed the influence of Wnt5A signaling on pathogenic E. coli K1 in relation to non-pathogenic E. coli K12-MG1655 and E. coli DH5α eliminating interspecies variability from our study. Whereas cell internalized E. coli K1 disrupted cytoskeletal actin organization and multiplied during Wnt5A depletion, rWnt5A ...
Tópico(s): Bacterial Infections and Vaccines
2021 - Frontiers Media | Frontiers in Immunology
Shanti Velmurugan, Vikas Kapil, Suborno M. Ghosh, Sheridan Davies, Andrew McKnight, Zainab Aboud, Rayomand S. Khambata, David J. Webb, Alastair W. Poole, Amrita Ahluwalia,
© 2015, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-No Derivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/
Tópico(s): Eicosanoids and Hypertension Pharmacology
2015 - Elsevier BV | Free Radical Biology and Medicine
MA Akter, Mohammad Ismail Hossain,
... pure seed was recorded in Agomoni, Jagoron, Gold, Suborno, Hira-1, Hira-2, Hira-4 and Hira- ...
Tópico(s): Plant Pathogens and Fungal Diseases
2016 - Bangladesh Agricultural University | Journal of the Bangladesh Agricultural University
Produção Nacional
Revisado por pares
Carla Alves Furio, Nayara Lopes Giomo, José Luiz Borsatto,
... dinheiro, pagamentos indevidos, tráfico de informações, fraudes e suborno. Em decorrência disso, constatou-se que a Petrobrás ...
Tópico(s): Supply Chain Resilience and Risk Management
2021 - UNIVERSIDADE FEDERAL DO RIO DE JANEIRO | Sociedade Contabilidade e Gestão
Produção Nacional
Notari Bonini Notari, Rogério Gesta Leal,
... às questões de ordem econômica, tais como, o suborno, fraudes, sonegação fiscal, propina, lavagem de dinheiro, tráfico ...
Tópico(s): Brazilian Legal Issues
2015 - UNIVERSIDADE ESTADUAL DE LONDRINA | Revista do Direito Público
Suborno Jati, Sumana Mahata, Soumita Das, Saurabh Chatterjee, Sushil K. Mahata,
The rapid increase in drug-resistant and multidrug-resistant infections poses a serious challenge to antimicrobial therapies, and has created a global health crisis. Since antimicrobial peptides (AMPs) have escaped bacterial resistance throughout evolution, AMPs are a category of potential alternatives for antibiotic-resistant “superbugs”. The Chromogranin A (CgA)-derived peptide Catestatin (CST: hCgA352–372; bCgA344–364) was initially identified in 1997 as an acute nicotinic-cholinergic antagonist. ...
Tópico(s): Nicotinic Acetylcholine Receptors Study
2023 - Multidisciplinary Digital Publishing Institute | Pharmaceutics
... as a crime in that time. “Peita” and “suborno” regard the practice of na act contrary to ... by the simple influence or demand of someone (“suborno”). This article aims to study the two mentioned ... Among the conclusions, the categorization of “peita”and “suborno” as “crimes of responsibility” and the special treatment ... corrupcao como crime aos delitos de peita e suborno, previstos no Codigo Criminal de 1830 e no Codigo Penal de 1890. Peita e suborno referem-se a pratica de um ato contrario ... ou pela simples influencia ou peditorio de outrem (suborno). Este artigo visa estudar os dois referidos delitos, ...
Tópico(s): Crime, Illicit Activities, and Governance
2017 - | Revista Brasileira de Ciências Criminais
Produção Nacional
Revisado por pares
Fernanda Ravazzano Lopes Baqueiro, João Glicério de Oliveira Filho, L. R. Silva,
... tem por objetivo discutir se o crime de suborno transnacional pode ser considerado crime de lesa humanidade, ... uma abordagem qualitativa, questionar se a consideração do suborno transnacional como crime de lesa humanidade seria possível, ...
Tópico(s): Corporate Law and Human Rights
2024 - CENTRO UNIVERSITÁRIO DE BRASÍLIA | Revista de Direito Internacional
Produção Nacional
Revisado por pares
... do comércio global, por meio da criminalização do suborno internacional, compreende a proteção do meio ambiente. Neste ... discussão do bem jurídico protegido no crime de suborno em transações comerciais internacionais. Por isso, a adequação ...
Tópico(s): Criminal Justice and Penology
2023 - UNIVERSIDADE FEDERAL DE SANTA CATARINA | Seqüência estudos jurídicos e políticos
Carlos Augusto de Oliveira Carvalhar,
... século V, bem como abordará a corrupção e suborno que foi feita a partir desse método de ... em sentido largo, como também aquela motivada por suborno.
Tópico(s): Brazilian Legal Issues
2021 - | CALÍOPE Presença Clássica
Satadeepa Kal, Sumana Mahata, Suborno Jati, Sushil K. Mahata,
Mitochondrial-derived peptides (MDPs) are a novel class of bioactive microproteins encoded by short open-reading frames (sORF) in mitochondrial DNA (mtDNA). Currently, three types of MDPs have been identified: Humanin (HN), MOTS-c (Mitochondrial ORF within Twelve S rRNA type-c), and SHLP1–6 (small Humanin-like peptide, 1 to 6). The 12 S ribosomal RNA (MT-RNR1) gene harbors the sequence for MOTS-c, whereas HN and SHLP1–6 are encoded by the 16 S ribosomal RNA (MT-RNR2) gene. Special genetic codes are used ...
Tópico(s): Adipose Tissue and Metabolism
2023 - Elsevier BV | Peptides
Soham Sengupta, Suborno Jati, Shreyasi Maity, Malini Sen,
Gut commensal bacterial diversity and T cell homeostasis are crucial entities of the host innate immune network, yet the molecular details of host-directed signaling pathways that sustain the steady state of gut bacterial colonization and T cell activation remain unclear. Here, we describe the protective role of a Wnt5A-actin axis in the survival of several gut bacterial commensals and its necessity in shaping gut bacterial colonization and the associated T cell repertoire.
Tópico(s): Pediatric health and respiratory diseases
2022 - American Society for Microbiology | mSphere
Matthew A. Liu, Shandy Shahabi, Suborno Jati, Kechun Tang, Hong Gao, Zhongmou Jin, W. Allen Miller, Frédéric A. Meunier, Wei Ying, Geert van den Bogaart, Gourisankar Ghosh, Sushil K. Mahata,
Aims Aging is associated with the development of insulin resistance and hypertension which may stem from inflammation induced by accumulation of toxic bacterial DNA crossing the gut barrier. The aim of this study was to identify factors counter-regulating these processes. Taking advantage of the Chromogranin A (CgA) knockout (CgA-KO) mouse as a model for healthy aging, we have identified Vsig4 (V-set and immunoglobulin domain containing 4) as the critical checkpoint gene in offsetting age-associated ...
Tópico(s): Tryptophan and brain disorders
2022 - Frontiers Media | Frontiers in Endocrinology
Tópico(s): Politics and Society in Latin America
1957 - UFU Faculty of Law Magazine | Revista da Faculdade de Direito Universidade de São Paulo
Produção Nacional
Revisado por pares
... transacoes que envolvem montantes milionarios, criando oportunidades para subornos. A Convencao Interamericana contra a Corrupcao, adotada em ...
Tópico(s): International Development and Aid
2009 - | Revista Direitos Fundamentais & Democracia
Mst. Arjina Akter, Ali Akbar Al Hasan, Sheikh Afsar Uddin, Ismail Hossain,
... Meghna, Hybrid super, Moyna, Tia, Gold, Aloron, Jagoron, Suborno, Safollo, Hira-1, Hira-2, Hira-4 and ...
Tópico(s): Seed Germination and Physiology
2016 - | Asian Journal of Medical and Biological Research
... comerciais internacionais. Emrazão do efeito nocivo da corrupção (suborno) transnacional ao comérciointernacional competitivo, iremos identificar o papel ...
Tópico(s): Business and Management Studies
2019 - Academia Nacional de Polícia | Revista de Direito de Polícia Judiciária
Suborno Debnath, Imran Ali, Ashutosh Sutra Dhar, Premkumar Thodi,
Municipal water distribution systems in Canada and other countries include a large number of cast iron pipes that were installed almost 50 years ago. For structural integrity assessment of these pipes, the fracture mechanics approach is found to be more effective than the conventional continuum mechanics-based approach. This paper presents the mechanical properties for fracture mechanics-based strength assessment of water mains determined through testing of cast iron pipes exhumed from two cities ...
Tópico(s): Water Systems and Optimization
2020 - NRC Research Press | Canadian Journal of Civil Engineering
Cesar A. Guimarães Pereira, Leonardo F. Souza-McMurtrie,
Tópico(s): Legal principles and applications
2024 - | Revista Brasileira de Arbitragem