Laura Aitken, Tunku Varadarajan, Alex Bennett, Helen Johnstone, Christopher Thomas, South Asia Correspondent, Patricia Davies, Grace Bradberry, Simon Barnes, Bill Frost, Andrew Longmore, John Blundell, General Director, Robert Ashby Executive Director, Ivo Tennant, Philip Howard, Susan Bell, Joanna Bale, Paul Eisler, Clive Davis, Kevin Marshall Chairman, H. A. Behenna, Nick Nuttall, Environment Correspondent, Gillian Maxey, Simon Wilde, Roger Maynard, Morag Preston, Michael Perham, Adrian Morgan, Eve-Ann Prentice, Diplomatic Correspondent, R. G. J. Winchester, John Cassy, Robert Sheehan, Bridge Correspondent, Jonathan Prynn, Transport Correspondent, Paul Braley, Fred Burrows, R. C. Copeman, Rupert Cox, John Hopkins, Golf Correspondent, Ann Scanlon, Norman Hammond, Archaeology Correspondent, John O'leary, Education Editor, L. Gilbert, John Ticehurst, Raymond Keene Chess Correspondent, Julia Neuberger, Roger Coombs, Thomas De Waal, Rodney Legg, Mark Cliffe, Richard Need, Alan Hamilton, Rupert Ridge, Mike Rosewell Rowing Correspondent, Jenny MacArthur, John Young, Janet Bush, Quentin Letts, David Hands, Charles Bremner, John O'leary, Michael Jeffels, Edward Gorman, Raymond Durrant, L. A. Partridge, Clive Bone, Nicole Swengley, Mark Ashford, George Brock, Sydney Friskin, John Hopkins, David Miller, Lin Jenkins, Harvey Elliott and Tunku Varadarajan, Scott Straus, Arthur Leathley, Political Correspondent, Raymond Keene, Su Stone, David Charter, Education Correspondent, Peter Davalle, Alan Lee, Cricket Correspondent, Emma Wilkins, Karen Zagor, Charles Mercer, Frances Gibb, Legal Correspondent, P. H. S, Peter Bryan, Nigel Hawkes, Eric Reguly, Oliver August, Stewart Tendler, Kate Alderson, Dalya Alberge, Winston Fletcher, Julian Muscat, R. W. Johnson, John Allison, Martin Waller, Deputy City Editor, MRS Mawe, William Rees-Mogg, John Goodbody, Nick Szczepanik, Ian Smith, Jason Nisse, Amelia, Christopher Walker, Robert Crampton, Mel Webb, Craig Lord, Jason Nissé, Matthew Parris, Jennai Cox, Anjana Ahuja, Michael Hornsby, Alan Lee, Peter Riddell, Ian Brodie, M. Derome, Frances Lass, Jason Cowley, Graham Searjeant, Tim Jones, Kate Bassett, Martin Waller, Michael Horsnell, Christopher Follett, Giles Coren and Jason Cowley, Marianne Curphey, Richard Morrison, Jack Bailey, Arthur Leathley, Michael Henderson, David Maddock, Matthew Bond, Edward Gorman Sailing Correspondent, Richard Ford, Colin McQuillan, Clement Freud, John Tincey, Russell,
... board Jennai Cox decides to give windsurfing a tyr , and discover the Women fall off less Often ...
1996 - Gale Group | TDA
... rates of hydrolysis of the peptides Glyn-L-Tyr by CPase in which n are 1, 2, ... Phe (3), Ala-3-Phe (3), Gly-L-Tyr (4, 5), Gly-L-Try (5), Gly-L-Leu (5), L-Tyr-L-Tyr (4) and Leu-L-Tyr (5). However, the introduction of glycyl residue to N-terminal position of L-Leu-L-Tyr resulted in remarkable increase in hydrolytic rate; Gly-L-Leu-L-Tyr was hydrolyzed 38 times more rapidly than L-Leu-L-Tyr (3)Plentl and Page have shown that the terminal peptide bond of the tetrapeptide L-Tyr-L-Lys-L-Glu-L-Tyr was susceptible ...
Tópico(s): Neuropeptides and Animal Physiology
1959 - Oxford University Press | The Journal of Biochemistry
Project Gutenberg
Liz Dolan, Paul Heiney, John Smith, Clifford Longley, Nick Nuttall, Douglas Broom and Neil Bennett, Christopher Warman, Property Correspondent, Patricia Davies, Jane MacQuitty, Simon Barnes, David Berry, Bill Frost, Neil Bennett, Charles Shaar Murray, Sheila Gunn, Political Correspondent, Bernard Kaukas, Michael Theodoulou and our Foreign Staff, Ivo Tennant, Norman Howell, Ross Tieman, Industrial Correspondent, Philip Howard, Laura Thompson, Ian Murray, James Abbott McNeill Whistler, David Lees, Sarah Jane Checkland, Art Market Correspondent, Lynne Truss, Richard Martin, Neil Bennett, Banking Correspondent, Colin Narbrough, Geoff Brown, Michael Tate, City Editor, Ray Clancy, Joe Joseph, Michael Seely Racing Correspondent, Molly Keane, Sanda Miller, John Watson, Mitchell Platts, Golf Correspondent, Andrew Longmore Tennis Correspondent, Madame de Sade, Stewart Tendler Crime Correspondent, Peter Ball, Ruth Gledhill, Sherban Cantacuzino, Secretary, John Browne, Mark Fuller and Sheila Gunn, John Street, Rachel Kelly, Robert Seely, Martin Barrow, Candida Crewe, Robin Young, Mike Rosewell Rowing Correspondent, Michael Clark, Nicola Murphy, Charles Bremner, Edward Gorman, Fiona MacCarthy, Tim Judah and Anne McElvoy, Graham Wood, Nicole Swengley, Michael McCarthy Environment Correspondent, Gavin Bell, Lindsay Cook Money Editor, Robin Oakley Political Editor, Gillian Bowditch, David Watts, Michael Watkins, Robin Oakley, Political Editor, V. Gardiner, David Powell Athletics Correspondent, Kerry Gill, David Robinson, John Russell Taylor, Raymond Keene, Chess Correspondent, Robin, John Parkes, Tom Millar, Ruth Gledhill, Religious Affairs Correspondent, Mary Ann, Alice Thomson, P. C. A. Wells, Giselda Hatch, Wellington, Michael HARPER(Chairman), Richard Duce, David Young, Tony Greenfield, Robert Cross, George Hill, Colin Narbrough, Economics Correspondent, G. H. Fleming, Charles Nevin, Matthew Parris, Graham Searjeant Financial Editor, Liz Smith, Colin Stewart, Cecil Helman, Peter Stothard, us Editor and Mary Dejevsky, Mr Lemon, Alan Lee, Sarah Jane Checkland, Alan Lee Cricket Correspondent, Michael Phillips, Shona Crawford, Michael Binyon, Diplomatic Editor, Peter Mulligan, Lindsay Cook Weekend Money Editor, Benedict Nightingale, Jonathan Meades, David Tytler, Education Editor, Jack Bailey, Richard Morrison, Nicholas Soames, Anne McElvoy, Gaudeamus, Mark Fuller, Matthew Bond, Colin Campbell, Susan Ellicott, Lindsay Cook and George Sivell, Judy Froshaug, David Hands, Rugby Correspondent, Tim Bevan, Mary Dejevsky, Brian W. Dennis, Jansen Raichl,
... Lingfield Park Mandarin: Ayr Mandarin: Chester Mandarin: Southwell Tyr looks best of trotters Rapid Raceline Switch Stage ...
1991 - Gale Group | TDA
Hiroyuki Yamamoto, Junzo Noguchi,
... carboxyl group of glutamyl residue in poly (L-Tyr-L-Glu), copoly (L-Tyr, L-Glu, L-Ala) and copoly (L-Tyr, L-Glu, L-Pro), þ-nitrophenyl acetate was ... activity relation showed a bell shape. Poly (L-Tyr-L-Glu), whose amino acid sequence is established, ... an optimal condition similar to random copoly (L-Tyr, L-Glu) as shown previously. However, the apparent Vmax of poly (L-Tyr-L-Glu) (0.8×10−6 M/min) was about 1/10 of copoly (L-Tyr, L-Glu) (9.4× 10−6M/min). Although the data suggests that the primary arrangement of Tyr-Glu is not essential to the activity, the ...
Tópico(s): Chemical Synthesis and Analysis
1970 - Oxford University Press | The Journal of Biochemistry
FROM OUR RACING CORRESPONDENT., FROM OUR NEWMARKET CORRESPONDENT., FROM OUR GOLF CORRESPONDENT., FROM OUR CRICKET CORRESPONDENT., D. S. MAC COLL., RICHARDSON EVANS., MERVYN MACKINNON., B. GRAHAM LITTLE., M. E. SIMKINS., HAROLD BRIGGS., HOWARD HODGKIN., ELINOR MORDAUNT., LAJPAT RAI., MORLEY DAINOW, W. J. C. HEWISON., DAVID C. LAMB., ARTHUR R. HOLBROOK., CLEMENT GATLEY., HERBERT BURY, , FROM OUR SPECIAL CORRESPONDENT., By CALLISTHENES., FROM A CORRESPONDENT., FROM OUR CHESS CORRESPONDENT., FROM OUR CAPE TOWN CORRESPONDENT., FROM OUR OWN CORRESPONDENT., FROM OUR CORRESPONDENT., FROM OUR CORRESPONDENT IN TURKEY., From Our Labour Correspondent., FROM OUR PARLIAMENTARY CORRESPONDENT., STANLEY BALDWIN., BALFOUR., BIRKENHEAD., RANDALL CANTUAR: CAVE., AUSTEN CHAMBERLAIN., DESBOROUGH., COSMO EBOR., ESHER., HARDINGE OF PENSHURST., M. R. JAMES., LANSDOWNE., A. D. LINDSAY., J. RAMSAY MACDONALD., MIDLETON., OXFORD., F. W. PEMBER., RONALDSHAY., SALISBURY., J. WELLS., J. W. TRUMBLE., PAGET TOYNBEE., By Our Special Correspondent.,
... Hon. W. E. Guinness (De Dawkins); Same (De Tyr); Re An Application Of Colonel, Sir Charles W. ...
1926 - Gale Group | TDA
Bilha Schechter, Abigail Conway‐jacobs, Michael Sela,
... wt. = 75 000) containing the repeating sequence–( l ‐Tyr‐ l ‐Ala‐ l ‐Glu)–and denoted as polypeptide (Tyr‐Ala‐Glu) n has previously been shown to ... whether monovalent fragments of antibodies derived from anti‐(Tyr‐Ala‐Glu) n antibodies could convert the partially helical oligopeptide (Tyr‐Ala‐Glu) 13 into a more helical conformation. ... of mixtures of the monovalent antibody fragments with (Tyr‐Ala‐Glu) 13 were measured at two different ... done with the same fragments and the polypeptide (Tyr‐Ala‐Glu) n . When anti‐(Tyr‐Ala‐Glu) ...
Tópico(s): Glycosylation and Glycoproteins Research
1971 - Wiley | European Journal of Biochemistry
Abigail Conway‐jacobs, Bilha Schechter, Michael Sela,
... l ‐alanine, and l ‐glutamic acid, denoted as(Tyr,Ala,Glu) n , and against the α‐helical ... l ‐tyrosyl‐ l ‐alanyl‐ l ‐glutamyl, denoted as (Tyr‐Ala‐Glu) n . Significant crossreactions were found between anti‐(Tyr‐Ala‐Glu) n antibodies and (Tyr,Ala,Glu) n , as well as between anti‐(Tyr,Ala,Glu) n antibodies and (Tyr‐Ala‐Glu) n . Small peptides, obtained from a ... Glu) n efficiently inhibited precipitin reactions between anti‐(Tyr,Ala,Glu) n and (Tyr,Ala,Glu) n , anti‐(Tyr,Ala,Glu) n and (Tyr‐Ala‐Glu) n , and anti‐(Tyr‐Ala‐Glu) ...
Tópico(s): Protein purification and stability
1971 - Wiley | European Journal of Biochemistry
Theodor Wieland, Christian Birr, Reinhilt Frodl, Werner Lochinger, Gisela Stahnke,
... Verwendung von O ‐Benzyl‐tyrosin aufgebaut und zwar: Tyr 5 ‐AA ( 1 ), Tyr 6 ‐AA ( 2 ), Tyr 9 ‐AA ( 3 ), Tyr 10 ‐AA ( 4 ), Ile 1 . Tyr 6 ‐AA ( 5 ), Ile 1 . Tyr 5 . Tyr 10 ‐AA ( 6 ), Gly 1 . Gly 4 . Tyr 5 ‐AA ( 7 ), Gly 1 . Gly 4 . Tyr 6 ‐AA ( 8 ), und Tyr 9 . des‐Ala‐AA ( 9 ). Die Cyclopeptide 1, ...
Tópico(s): Microbial Natural Products and Biosynthesis
1972 - Wiley | Justus Liebig s Annalen der Chemie
David J. Wilbur, Adam Allerhand,
... proteins yielded specific assignments for the resonance of Tyr-151 (sperm whale) and Tyr-103 (sperm whale and horse). Selective proton decoupling yielded specific assignments for Czeta of Tyr-146 of the cyanoferrimyoglobins from horse and kangaroo, ... dependence of the chemical shifts indicated that only Tyr-151 and Tyr-103 are titratable tyrosine residues. Even at pH 12, Tyr-146 did not begin to titrate. The titration behavior of C zeta and Cgamma of Tyr-151 of sperm whale cyanoferrimyoglobin yielded a single ...
Tópico(s): Advanced NMR Techniques and Applications
1976 - Elsevier BV | Journal of Biological Chemistry
... Phe, Leu-Phe, Phe-Leu, Phe-Val, Phe-Tyr, His-Phe, Gly-Tyr, Ala-Tyr, Val-Tyr, L-Leu-Tyr, D-Leu-Tyr, Trp-Tyr, Trp-Gly, and Tyr-Val, within the range 300–360 K. Iterative ... Gly, Gly-Phe-Ala, Gly-Phe-Phe, Gly-Tyr-Gly, and Val-Tyr-Val, within the range 280–360 K. In ...
Tópico(s): Food Quality and Safety Studies
1976 - Royal Society of Chemistry | Journal of the Chemical Society. Perkin transactions II
... biological activity. This initial reaction occurred at α Tyr-88 and/or α Tyr-89. Exhaustive nitration of the hormone modified α ... nitrated monomer. These results indicate involvement of α Tyr-88 and/or α Tyr 89 in binding of the hormone to its ... required for binding to the β subunit, however. Tyr-65 of the α subunit is probably not ... isolated α subunit fully converted the remaining tyrosine (Tyr-37) to 3-nitrotyrosine in a two-step ... less of the native activity. Involvement of α Tyr-37 in binding to the β subunit is ...
Tópico(s): Electron Spin Resonance Studies
1976 - Elsevier BV | Archives of Biochemistry and Biophysics
Dieter Vogel, Rainer Jaenicke,
... Comparing wild‐type protein and mutant Ni 2068 (Tyr‐139→Cys‐139) a tentative localization of aromatic ... Trp‐17 and Trp‐52 as well as Tyr‐70, Tyr‐72 and Tyr‐139. The Trp‐1 7Trp‐52 interaction was ... 17‐Trp‐52 interactions. It is suggested that Tyr‐70 and Tyr‐72 form hydrogen bonds in a strongly hydrophobic ... conformational flexibility. Spectroscopic and chemical evidence prove that Tyr‐70, Tyr‐72 and Tyr‐139 are in close neighbourhood. Double disc formation ... by identical spectral effects in the environment of Tyr‐70‐Tyr‐72. However the interaction between Trp‐ ...
Tópico(s): Bacterial Genetics and Biotechnology
1976 - Wiley | European Journal of Biochemistry
Michal Schwartz, Edna Mozes, Michael Sela,
... inbred mouse strains to the ordered synthetic antigen (Tyr‐Tyr‐Glu‐Glu)‐A‐‐L is similar to that ... C3H.SW mice in response to the ordered (Tyr‐Tyr‐Glu‐Glu)‐A‐‐L. Genetic analysis experiments demonstrated ... close linkage between the ability to respond to (Tyr‐Tyr‐Glu‐Glu)‐A‐‐L and the major histocompatibility ...
Tópico(s): Biopolymer Synthesis and Applications
1975 - Wiley | European Journal of Immunology
Bahjat A. Faraj, 俊英 鈴木, Marc S. Lewis, James P. Wilson, Zafar H. Israili, Peter G. Dayton,
... diazotized an attached to the aromatif ring of TYR. The immunogen in Freund's complete adjuvant was ... antibody was determined by radioimmunoassay. Using random-labeled TYR-3H, TYR, its metabolites, phenethylamine analogs, catecholamines, and certain amino ... assay method. With this technique 4 ng of TYR inhibited the binding of TYR-3H by 50%. The radioimmunoassay of TYR was used to measure the plasma, urine, and tissue levels of TYR in rabbits. The plasma disappearance curve of TYR revealed a biphasic pattern with t1/2 of ...
Tópico(s): Mast cells and histamine
1975 - SAGE Publishing | Experimental Biology and Medicine
Howard A. Levin, Martin Becker, Michael Sela,
The denned compounds containing p ‐azobenzenearsonate (Aba), Aba‐Tyr, Aba‐Tyr‐Tyr, Aba‐Tyr‐(Tyr) 2 , Aba‐Tyr‐(Tyr) 3 , (Tyr) 3 ‐Aba‐Tyr and Aba‐Tyr‐(Ala) 3 (where Tyr is l ‐tyrosine and ...
Tópico(s): Immune Response and Inflammation
1974 - Wiley | European Journal of Biochemistry
Ta‐Hsiu Liao, Johann Salnikow, Stanford Moore, William H. Stein,
... Ser-i\sn-30 Alo-~~~-Leu-Alo-Ser-Tyr-Ile-Vol-Arg-Arg-Tyr-Asp-Ile-Vol-Leu-Ile-Glu-Gln-Vol- ... Val-Ala-Val-Gly-Lys-Leu-Leu-Asp-Tyr-Leu-Asn-Gln-Asp-Asp-60 70 ho-Asn-Thr-Tyr-His-Tyr-Val-Val-Ser-Glu-Pro-Leu-Gly-Arg-Asn-Ser-Tyr-Lys-Glu-80 90 Arg-Tyr-Leu-Phe-Leu-Phe-Arg-Pro-Asn-Lys-Vol-Ser-Val-Leu-Asp-Thr-Tyr-Gln-Tyr-100 110 Asp-Asp-Gly-Cys-Glu-Ser- ... Ala-Val-Ala-Glu-lle-Asn-Ser-Leu-Tyr-Asp-Val-Tyr-Leu-Asp-Val-160 170 ...
Tópico(s): Adenosine and Purinergic Signaling
1973 - Elsevier BV | Journal of Biological Chemistry
Johannes A. Lenstra, Ben G.J.M. Bolscher, S. Stob, Jaap J. Beintema, Robert Kaptein,
... 3. The resonances of the ring protons of Tyr-25, Tyr-76 and Tyr-115 and the C-4 proton of His- ... nitrated ribonucleases. Other resonances were assigned tentatively to Tyr-73, Tyr-92 and Phe-46. 4. On addition of ... the six tyrosines of bovine RNase, identified as Tyr-76, Tyr-115 and, tentatively, Tyr-73 and Tyr-92, are titratable above pH 9. The rings of Tyr-73 and Tyr-115 are rapidly rotating or ...
Tópico(s): Biochemical and Molecular Research
1979 - Wiley | European Journal of Biochemistry
Paul Canioni, Patrick J. Cozzone,
... pour His II (His 86), 10,4 pour Tyr I (Tyr 56 ou 57), 10,3 pour Tyr II (Tyr 56 ou 57) et 11,3 pour Tyr III (Tyr 53). La valeur élevée du pKa du résidu ... 31. La rotation du cycle aromatique du résidu Tyr 53 autour de l'axe Cβ -Cγ est ... évidence une interaction spécifique entre His 86 et Tyr I. Le résidu Tyr II est également affecté mais à un degré ... His I (His 30), His II (His 86), Tyr I (Tyr 56 or 57), Tyr II (Tyr ...
Tópico(s): Computational Drug Discovery Methods
1979 - Elsevier BV | Biochimie
Michal Schwartz, Behnaz Parhami, Edna Mozes, Michael Sela,
The crossreactivity between the random synthetic polypeptide antigen, (Tyr,Glu)-poly(DLAla)- -poly(Lys), and its ordered sequence analogs, (Tyr-Tyr-Glu-Glu)-poly(DLAla)- -poly(Lys) and (Tyr-Glu-Tyr-Glu)-poly(DLAla)- -poly(Lys), has been studied ... tolerance induction. Induction of tolerance to the random (Tyr,Glu)-poly(DLAla)- -poly(Lys) affected the response ... to the homologous antigen as well as to (Tyr-Tyr-Glu-Glu)-poly(DLAla)- -poly(Lys), which was shown previously to represent the major determinant of (Tyr,Glu)-poly(DLAla)- -poly(Lys). In contrast, these ...
Tópico(s): Radiopharmaceutical Chemistry and Applications
1979 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Ulrike Schmidt-Aderjan, Paul Rösch, Rainer Frank, Wolfgang Hengstenberg,
... the amino acid sequence. In mononitrated HPr only Tyr‐56 was modified, in dinitrated HPr both Tyr‐56 and Tyr‐37 had reacted with the nitrating agent; modification ... the assignments of the tyrosine resonances as follows: Tyr‐A and Tyr‐B with p K values of 10.5 and 11.5 were designated Tyr‐56 and Tyr‐37 whereas Tyr‐C, whose protons are not titratable before denaturation of the protein, was assigned to Tyr‐6 in the amino acid sequence. The nitration ... of the tyrosyl residues to be as follows: Tyr‐56 is located at the surface, Tyr‐37 ...
Tópico(s): Enzyme Structure and Function
1979 - Wiley | European Journal of Biochemistry
F. Sodoyez‐Goffaux, J. C. Sodoyez, C. J. De Vos,
Purified carrier-free 125I-Tyr insulin (125I-Tyr Ins) was injected into the vitelline vein of rat fetuses in utero after 17, 19, or 21 days of gestation. Three minutes later, ... and 21 days of gestation). Binding of 125I-Tyr Ins to the liver was inhibited by coinjection of excess unlabeled insulin. Sequential injections of 125I-Tyr Ins followed by excess unlabeled insulin demonstrated that 125I-Tyr Ins binding to the liver was but partly ... analysis, liver radioactivity appeared composed of undamaged 125I-Tyr Ins and low mol. wt. degradation products (125I- ...
Tópico(s): Renal and related cancers
1982 - American Diabetes Association | Diabetes
James E. Zadina, Abba J. Kastin, Edward F. Krieg, David H. Coy,
Binding sites for N-Tyr-Pro-Leu-Gly-NH2 (Tyr-MIF-1), a novel peptide structurally related but immunoreactively different from Pro-Leu-Gly-NH2 (MIF-1), were investigated. The presence of Tyr-MIF-1-like material in brain tissue has ... rat brain that is saturable and specific for Tyr-MIF-1. Crude P2 synaptosomal fractions from rat brains were incubated with 125I-Tyr-MIF-1 in the presence or absence of μM unlabelled Tyr-MIF-1 (nonspecific binding). Binding reached equilibrium at ... tested were found to effectively compete for 125I-Tyr-MIF-1 binding. Binding was linear with protein ...
Tópico(s): Cardiovascular, Neuropeptides, and Oxidative Stress Research
1982 - Elsevier BV | Pharmacology Biochemistry and Behavior
Gilda H. Loew, Gail M. Hashimoto, Lainey J. Williamson, S. K. Burt, W. Gary Anderson,
The conformational behavior of four tetrapeptide enkephalin analogues (Tyr-Gly-Gly-Phe-OH, Tyr-Gly-Gly-Phe-NH2, Tyr-D-Ala-Gly-Phe-NH2, and Tyr-D-Ala-Gly-(NMe)Phe-NH2) was examined ... low-energy conformations of the very weak tetrapeptide, Tyr-Gly-Gly-Phe-OH. These candidate inactive conformers ... selected were low-energy conformations found for both Tyr-D-Ala-Gly-Phe-NH2 and Tyr-D-Ala-Gly-(NMe)Phe-NH2 but not low-energy conformers for Tyr-Gly-Gly-Phe-OH. In the second method ... and inactive peptides that followed the potency order Tyr-Gly-Gly-Phe-OH much less than Tyr- ...
Tópico(s): Receptor Mechanisms and Signaling
1982 - American Society for Pharmacology and Experimental Therapeutics | Molecular Pharmacology
T H Liao, Ruby Ting, Jennifer Yeung,
... tyrosine which yields 0-(p-nitrobenzenesulfonyl) tyrosine (NBS-Tyr) after acid hydrolysis.The extent of modification can be measured as NBS-Tyr by high performance liquid chromatography (HPLC).The reagent ... 50% inactivation, the number of residues of NBS-Tyr was approximately 1 in Ca2+-DNase and 2. ... forms modified by the reagent.Peptides containing NBS-Tyr were identified by comparing absorbances at 254 nm ... summarized as follows.(a) In Ca2+-free DNase, Tyr-62 reacts about 20 times faster than N-acetyltyrosine (N-Ac-Tyr), but its modification does not affect enzymic activity; ...
Tópico(s): Biochemical and Molecular Research
1982 - Elsevier BV | Journal of Biological Chemistry
Robert Akeroyd, Peter Moonen, Jan Westerman, W. C. Puyk, K.W.A. Wirtz,
... Glu‐Thr‐Gln‐Gly‐Ile‐Ser 40 ‐Val‐Tyr‐Arg‐Leu‐Leu‐Asp‐Gln‐Gln‐Thr‐Gly 50 ‐Leu‐Tyr‐Ala‐Tyr‐Lys‐Val‐Phe‐Gly‐Val‐Leu 60 ‐Glu ‐ ... Pro‐Asp‐Leu‐Leu‐Ala‐Asp 70 ‐Val‐Tyr‐Met‐Asp‐Leu‐Ala‐Tyr‐Arg‐Lys‐Gln 80 ‐Trp‐Asp‐Gln‐Tyr‐Val‐Lys‐Glu‐Leu‐Tyr‐Glu 90 ‐Lys‐Glu‐Cys‐Ser‐Gly‐Glu‐Thr‐Val‐Val‐Tyr 100 ‐Trp‐Gin‐Val‐Lys‐Tyr‐Pro‐Phe‐Pro‐Met‐Ser 110 ‐Asn‐Arg‐Asp‐Tyr‐Val‐Tyr‐Val‐Arg‐Gln‐Arg 130 ‐Gln‐ ...
Tópico(s): Lipid Membrane Structure and Behavior
1981 - Wiley | European Journal of Biochemistry
P. Roesch, Hans Robert Kalbitzer, Ulrike Schmidt-Aderjan, Wolfgang Hengstenberg,
... dinitrated, and trinitrated derivatives--i.e., derivatives with Tyr-56, Tyr-56 and Tyr-37, and Tyr-56, Tyr-37, and Tyr-6 modified--have been performed. The three tyrosyl ... each other with respect to their solvent accessibility; Tyr-56 seems to be located near the surface of the protein, Tyr-6 seems to be completely buried, and Tyr-37 takes an intermediate position. Tyr-6 contributes to the core structure of the ...
Tópico(s): Protein Structure and Dynamics
1981 - American Chemical Society | Biochemistry
Yehiel Zick, George Grunberger, R W Rees-Jones, Richard J. Comi,
... tyrosine residues at a 4:1 ratio (Glu/Tyr, 4:1). The insulin‐stimulated phosphorylation of this ... detect. Other tyrosine‐containing polymers Ala/Glu/Lys/Tyr (6:2:5:1) and Glu/Ala/Tyr (6:3:1) were also phosphorylated by the ... phorbol ester also best phosphorylated the polymer Glu/Tyr (4:1). The three kinases differed only in their capability to phosphorylate Glu/Ala/Tyr (6:3:1) or Ala/Glu/Lys/Tyr (6:2:5:1). Glu/Tyr (4:1) was a poor substrate for the ... kinase which best phosphorylated the polymer Glu/Ala/Tyr (6:3:1). Three additional polymers: Glu/Tyr ( ...
Tópico(s): Protein Kinase Regulation and GTPase Signaling
1985 - Wiley | European Journal of Biochemistry