L. Cubeddu, Evelyn Santiago, R K Talmaciu, G. Pinardi,
Controlled hemorrhagic hypotension in anesthetized dogs causes progressive increases in dopamine beta-hydroxylase (DBH) and catecholamine (CA) plasma levels and in heart rate. The concentration (units per milliliter) and the calculated total plasma content of DBH activity [(units circulating + reservoir + samples] increased 2.6 and 2.3 times, respectively. A significant positive correlation (P less than .001) was found between the plasma levels of DBH and CA; however, the CA plasma levels increased earlier ...
Tópico(s): High Altitude and Hypoxia
1977 - American Society for Pharmacology and Experimental Therapeutics | Journal of Pharmacology and Experimental Therapeutics
Hidefumi Hirai, Kazuhiko Takeuchi, Makoto Komiyama,
... Science®Google Scholar 10 B. C. Simionescu, V. Talmaciu, V. Barboiu, and C. I. Simionescu, Polym. Bull. ...
Tópico(s): Advanced Polymer Synthesis and Characterization
1985 - Wiley | Journal of Polymer Science Polymer Chemistry Edition
Luigi X. Cubeddu, Irene Hoffmann, R K Talmaciu,
Results obtained from our in vitro studies employing superfused slices obtained from three functionally different brain regions rich in DA axon terminals were discussed. Striking qualitative and quantitative similarities were found for the modulation of DA release from the nucleus caudate and the OT of the rabbit. However, the PFC DA terminals showed important differences from the nigrostriatal and mesolimbic DA terminals. Although release modulatory D2 DA autoreceptors could also be demonstrated ...
Tópico(s): EEG and Brain-Computer Interfaces
1990 - Wiley | Annals of the New York Academy of Sciences
... 90009-1 Web of Science®Google Scholar 82 Talmaciu, R. K., I. S. Hoffmann & L. Y. Cubeddu. ...
Tópico(s): Neurotransmitter Receptor Influence on Behavior
1990 - Wiley | Annals of the New York Academy of Sciences
R K Talmaciu, Irene Hoffmann, Luigi X. Cubeddu,
Electrical stimulation (at 0.3, 1, or 10 Hz, 120 pulses each) produced a calcium-dependent overflow of radioactivity from slices of the rabbit prefrontal cortex preloaded with [3H]3,4-dihydroxyphenylethylamine ([3H]DA, [3H]dopamine) in the presence of desipramine. Flat frequency-release curves were observed. Apomorphine and LY-171555 inhibited in a concentration-dependent fashion the evoked overflow of DA, an effect antagonized by haloperidol. Stimulation frequencies comparable to normal firing rates ...
Tópico(s): Neurotransmitter Receptor Influence on Behavior
1986 - Wiley | Journal of Neurochemistry
Irene Hoffmann, R K Talmaciu, Luigi X. Cubeddu,
The authors investigated the mechanisms by which inhibitors of the neuronal uptake (NUI) of dopamine (DA) and prolonged stimulations at high rates antagonize the inhibition of acetylcholine (ACh) release from rabbit striatal slices produced by DA receptor agonists. Nomifensine (1 microM) reduced the potency and efficacy of apomorphine (APO) in inhibiting the evoked release of ACh (0.3 Hz, 39 pulses) (noncompetitive kinetics). Highest inhibitory potency and efficacy of APO were obtained at 0.3 Hz and 39 ...
Tópico(s): Neuroscience and Neuropharmacology Research
1986 - American Society for Pharmacology and Experimental Therapeutics | Journal of Pharmacology and Experimental Therapeutics
Luigi X. Cubeddu, Timothy W. Lovenberg, István Hoffman, R K Talmaciu,
4-beta-Phorbol-12,13-dibutyrate (PDBu), a powerful activator of protein kinase C (PKC), enhanced dopamine (DA) release evoked by electrical stimulation (1 Hz, 2 min) from the striatum and the prefrontal cortex of the rabbit. However, acetylcholine (ACh) release from the striatum (1 Hz, 2 min), was only enhanced slightly by PDBu. The increase in DA release induced by PDBu was reduced markedly at higher frequencies of stimulation. Sulpiride (10 microM) alone, a D2 DA-receptor antagonist, or combined with ...
Tópico(s): Neurotransmitter Receptor Influence on Behavior
1989 - American Society for Pharmacology and Experimental Therapeutics | Journal of Pharmacology and Experimental Therapeutics
Irene Hoffmann, R K Talmaciu, C P Ferro, Luigi X. Cubeddu,
The release of dopamine (DA) from mesocortical and nigrostriatal nerve terminal fields, as well as its modulation by auto- and heteroreceptors was investigated. Rabbit brain slices obtained from medial prefrontal cortex (PFC) and nucleus caudate (striatum) were prelabeled with [3H]DA in the presence of 0.3 microM desipramine. Neuronal depolarization was elicited by electrical stimulation. Higher stimulation-evoked overflow of [3H]DA (release) was observed from PFC than from striatal slices. At 0.3 Hz ( ...
Tópico(s): Neurotransmitter Receptor Influence on Behavior
1988 - American Society for Pharmacology and Experimental Therapeutics | Journal of Pharmacology and Experimental Therapeutics
... 270–275. CASPubMedWeb of Science®Google Scholar 64 Talmaciu, R. K., I. S. Hoffmann & L. X. Cubeddu. ...
Tópico(s): Tryptophan and brain disorders
1988 - Wiley | Annals of the New York Academy of Sciences
Isaac Talmaciu, Clement L. Ren, S Kolb, Eileen M. Hickey, Howard B. Panitch,
Abstract Somatic and pulmonary growth coincide with resolution of hypoxemia by 2 years of age in most children with bronchopulmonary dysplasia (BPD). However, a distinct subgroup of children with BPD continue to require mechanical ventilation and/or supplemental oxygen beyond 2 years of age. This study tested the hypothesis that indices of pulmonary function would be significantly worse in children with BPD 2 years and older who remained technology‐dependent secondary to hypoxemia, compared to those ...
Tópico(s): Congenital Diaphragmatic Hernia Studies
2002 - Wiley | Pediatric Pulmonology
María Dolores del Toro, Jesús Rodríguez‐Baño, Marta Herrero, Antonio Rivero, Miguel Ángel García-Ordóñez, Juan E. Corzo, ROGELIO PÉREZ-CANO,
... Multivariate analysis was not performed in that study. Talmaciu et al (56) found that several factors related ...
Tópico(s): Antimicrobial Resistance in Staphylococcus
2002 - Wolters Kluwer | Medicine
Iordan C. Matulea, Alexandru Năstase, Nicoleta Tălmaciu, Georgică Slămnoiu, António Gonçalves-Coelho,
Marine compound mooring and towing cables are usually formed by cables, chains, buoys and underwater bodies. They are exposed to the action of the water in relative motion, and hence the need to predict the static configuration of these complex mechanical systems under typical conditions from the early stages of the design process. This paper introduces a new mathematical model and a matching numerical method based on finite differences, in order to predict the static configuration of mooring or ...
Tópico(s): Marine and Offshore Engineering Studies
2008 - Elsevier BV | Applied Ocean Research
Isaac Talmaciu, Laurie Varlotta, Joel E. Mortensen, Daniel V. Schidlow,
The number of patients with cystic fibrosis (CF) whose sputum culture has yielded Stenotrophomonas maltophilia has increased in the last 5 years at St. Christopher's Hospital for Children. We conducted a case-control study to determine risk factors for recovery of S. maltophilia in respiratory secretions from patients with CF. We reviewed the outpatient and inpatient records of patients colonized with S. maltophilia between 1993 and 1997, and of age-matched (at time of initial recovery of S. maltophilia) ...
Tópico(s): Plant Pathogenic Bacteria Studies
2000 - Wiley | Pediatric Pulmonology
Adina Iulia Talmaciu, Irina Volf, Valentin Popa,
From all the valuable biomass extractives, polyphenols are a widespread group of secondary metabolites found in all plants, representing the most desirable phytochemicals due to their potential to be used as additives in food industry, cosmetics, medicine, and others fields. At present, there is an increased interest to recover them from plant of spontaneous flora, cultivated plant, and wastes resulted in agricultural and food industry. That is why many efforts have been made to provide a highly ...
Tópico(s): Plant biochemistry and biosynthesis
2015 - Wiley | Chemistry & Biodiversity
Oana-Crina Bujor, IULIA ADINA TALMACIU, Irina Volf, Valentin Popa,
Although extraction of bioactive compounds by biomass resource biorefining is challenging, interest in these compounds is increasing. This review summarizes our results in the field of secondary compounds (especially polyphenols) obtained via biorefining technology. The technology also offers the possibility to separate other compounds with industrial value or biological properties. To isolate polyphenols, different biomass sources such as spruce wood bark, Asclepias syriaca (a latex-bearing plant), ...
Tópico(s): Botanical Studies and Applications
2015 - TAPPI | TAPPI Journal
Irina Volf, Adina Iulia Talmaciu, Valentin Popa,
Supercritical fluid and ultrasound assisted extractions were applied as a first step in a complex processing of spruce bark in order to recover polyphenols compounds.The aim of the study was to compare the efficiency of these "green" processes with a conventional extraction technique (ethanolic extraction).Supercritical fluid extraction was carried out in two steps: (i) static extraction for 15 min at 1000 psi with pure CO 2 and (ii) dynamic extraction for 45 min at 35, 40 and 50 0 C, 1200, 2000 and ...
Tópico(s): Analytical chemistry methods development
2015 - Polytechnic Institute of Iasi | Environmental Engineering and Management Journal
Igor V. Tetko, Hristo P. Varbanov, M. Galanski, Mona Maria Talmaciu, James A. Platts, Mauro Ravera, Elisabetta Gabano,
The octanol/water partition coefficient, logP, is one of the most important physico-chemical parameters for the development of new metal-based anticancer drugs with improved pharmacokinetic properties. This study addresses an issue with the absence of publicly available models to predict logP of Pt(IV) complexes. Following data collection and subsequent development of models based on 187 complexes from literature, we validate new and previously published models on a new set of 11 Pt(II) and 35 Pt( ...
Tópico(s): Free Radicals and Antioxidants
2015 - Elsevier BV | Journal of Inorganic Biochemistry
Adina Iulia Talmaciu, Matej Ravber, Irina Volf, Željko Knez, Valentin Popa,
The aim of this study was to investigate the possibility of isolating bioactive phenolics compounds from spruce bark (Picea abies), using sub- and supercritical fluids. In order to improve the yields and to assure a higher recovery of the phenolic compounds, in the first part of this study, extraction of lipophilic compounds was performed using only supercritical (SC) CO2 as solvent. Amount of obtained lipophilic compounds was quantified. In the second step, to the SCCO2 a cosolvent was added, namely ...
Tópico(s): Plant biochemistry and biosynthesis
2016 - Elsevier BV | The Journal of Supercritical Fluids
Liliana Lazăr, Adina Iulia Talmaciu, Irina Volf, Valentin Popa,
In this paper, the kinetics of polyphenols extraction from spruce bark (Picea abies) under ultrasounds action was investigated. Studies were performed in order to express the effect of some specific parameters (as: ultrasounds, surface contact between solvent and solid, extraction time and temperature) on the total phenolic content (TPC). Experiments were performed in the presence and absence of ultrasounds, using different contact surfaces between solvent and solid, for times from 5 to 75min and temperatures ...
Tópico(s): Antioxidant Activity and Oxidative Stress
2016 - Elsevier BV | Ultrasonics Sonochemistry
Mona Maria Talmaciu, Ede Bodoki, Radu Oprean,
Background and aim. Beta-adrenergic antagonists have been established as first line treatment in the medical management of hypertension, acute coronary syndrome and other cardiovascular diseases, as well as for the prevention of initial episodes of gastrointestinal bleeding in patients with cirrhosis and esophageal varices, glaucoma, and have recently become the main form of treatment of infantile hemangiomas.The aim of the present study is to calculate for 14 beta-blockers several quantum chemical ...
Tópico(s): Chemical Thermodynamics and Molecular Structure
2016 - | Medicine and Pharmacy Reports
Luigi X. Cubeddu, Lesbia Trujillo, Isaac Talmaciu, V.A. González-Delgado, J. Guariguata, J. SEIJAS, Irene Miller, W. Paska,
Background : The mechanism of nausea and vomiting associated with gastroenteritis is unknown. The role of 5‐HT 3 receptors in emesis associated with gastroenteritis was investigated in paediatric patients. Methods : A randomized, double‐blind, placebo‐controlled, parallel‐group study was conducted in three groups of 12 patients each, receiving either a single i.v. dose of ondansetron (0.3 mg/kg), metoclopramide (0.3 mg/kg) or placebo (sterile saline). Food was restricted and oral rehydration was administered ...
Tópico(s): Pathogenesis and Treatment of Hiccups
1997 - Wiley | Alimentary Pharmacology & Therapeutics
Howard B. Panitch, Isaac Talmaciu, J. L. Heckman, Marla R. Wolfson, Thomas H. Shaffer,
To date, quantitative studies of the inherent characteristics of the developing airway wall have required excision of an airway segment or surgical creation of an isolated segment. We hypothesized that airway wall characteristics, at various collapsing pressures, and attendant changes in stiffness after smooth muscle stimulation could be quantitated bronchoscopically from airway pressure-area relationships. Neonatal lamb tracheal segments (n = 12) were suspended over hollow mounts, in a buffer-filled ...
Tópico(s): Airway Management and Intubation Techniques
1998 - Springer Nature | Pediatric Research
Philipp J. Kremer, Andreea Talmaciu, Sandra Paterlini,
Tópico(s): Stochastic processes and financial applications
2017 - Springer Science+Business Media | Annals of Operations Research
Ioan Șușnea, Luminiţa Dumitriu, Mihai Tălmaciu, Emilia Pecheanu, Dan Munteanu,
Most expert projections indicate that in 2030, there will be over one billion people aged 60 or over. The vast majority of them prefer to spend their last years at home, and almost a third of them live alone. This creates a growing need for technology-based solutions capable of helping older people to live independently in their places. Despite the wealth of solutions proposed for this general problem, there are very few support systems that can be reproduced on a larger scale. In this study, we ...
Tópico(s): Video Surveillance and Tracking Methods
2019 - Multidisciplinary Digital Publishing Institute | Sensors
Corneliu Tănase, Lavinia Berța, Anca Delia Mare, Adrian Man, Adina Iulia Talmaciu, Ioana Roșca, Eleonora Mircia, Irina Volf, Valentin Popa,
Tópico(s): Nanotechnology research and applications
2020 - Springer Science+Business Media | European Journal of Wood and Wood Products
Mihai Tălmaciu, Elena Nechita,
In this paper we recall the notion of weakly decomposition, we recall some necessary and sufficient conditions for a graph to admit such a decomposition, we introduce the recognition algorithm for the diamond-free graphs which keeps the combinatorial structure of the graph by means of the decomposition, as well as an easy possibility to determine the clique number for the diamond-free graphs.
Tópico(s): Limits and Structures in Graph Theory
2007 - IOS Press | Informatica
G. Pinardi, R K Talmaciu, Evelyn Santiago, Luigi X. Cubeddu,
Tópico(s): Diet and metabolism studies
1979 - American Society for Pharmacology and Experimental Therapeutics | Journal of Pharmacology and Experimental Therapeutics
The regional development in EU countries is strongly institutionalized and shaped by politics, strategies and financial allocations through the Structural Funds. In this context, factors such as institutional framework, regional/local leadership and quality of regional/local governance can play an important role in supporting the efforts of residents towards economic and social development and to mitigate the significant gap that separates the lagging regions to those developed.Good institutions, ...
Tópico(s): International Business and FDI
2014 - Elsevier BV | Procedia Economics and Finance
In the current global economic situation characterized by increasingly processes of globalization and the growing need to promote the principles of sustainability in economic development, more and more theorists of development and development policy makers insist on the necessity of taking into account as key factors in ensuring long term economic growth: innovation and the ability to generate new knowledge, entrepreneurship and promotion of leading technologies at the global technological frontier, ...
Tópico(s): Global Trade and Competitiveness
2012 - Elsevier BV | Procedia Economics and Finance
Corneliu Tănase, Adina Iulia Talmaciu, Iuliana Csilla Bâra, Irina Boz, Irina Volf, Silvia Oroian, Valentin Popa,
The effects of spruce bark crude extracts were evaluated relative to basil (Ocimum basilicum L.) plantlet development and metabolic processes (cellular division and histo-anatomical modification) involved in breeding. Natural phenolic compounds were separated as crude extracts by conventional and green extraction techniques, in a primary biorefining process, from Picea abies L. waste bark. First, the influence of phenolic compounds, in different concentrations, on the basil plants' main biosynthetic ...
Tópico(s): Bioenergy crop production and management
2018 - North Carolina State University | BioResources