Taito Okamura, Mitsuaki Morimoto, Gen‐yuki Yamane, Shinichi Takahashi,
SUMMARY We created a murine model of delayed-type hypersensitivity (DTH) to 1-chloro-2, 4-dinitrobenzene (DNCB). Using this murine model, we compared oral mucosal sensitization and skin sensitization for the difference in reaction during the elicitation phase. Evaluation of sensitizability, using the mouse ear swelling test (MEST) after oral mucosal or skin sensitization, showed that the ear swelling response peaked 24 h after challenge. The optimal induction concentration was 1·0% in both oral mucosal ...
Tópico(s): Dermatology and Skin Diseases
2003 - Oxford University Press | Clinical & Experimental Immunology
Akihiko Takada, Takeshi Fukuda, Taito Miyamoto, Y. Yakoh, Junji Watanabe,
Abstract A series of cellobiose octaalkanoates, Cel-II-n (n is the carbon number of the alkyl chain), with n = 7–14 were prepared and their mesogenic properties examined by differential scanning calorimetry, optical polarizing microscopy and X-ray diffraction. All of these compounds form enantiotropic discotic columnar phases, in which the columns are built up by a regular stacking of the cellobiose moieties and are packed in a two dimensional lattice. Homologues with n = 9–14 form the Dho phase only ...
Tópico(s): Plant Reproductive Biology
1992 - Taylor & Francis | Liquid Crystals
Makoto Sugiura, Masahiko Minoda, Takeshi Fukuda, Taito Miyamoto, Junji Watanabe,
Abstract Chitobiose octaalkanoates and chitotriose hendecaalkanoates with varying acyl pendant lengths were synthesized and their mesophase properties studied. Both series of derivatives showed an enantiotropic mesophase in a wide temperature region below 200°C. An X-ray diffraction analysis revealed the mesophase to be of a hexagonal columnar type, in which the columns built up by a periodic stacking of chitobiose or chitotriose cores are packed into a two dimensional hexagonal lattice. The mesophase ...
Tópico(s): Plant Reproductive Biology
1992 - Taylor & Francis | Liquid Crystals
Taito Takeda, Yuko Suwa, Makoto Suzuki, Hidemi Kitano, Miyako Ueguchi‐Tanaka, Motoyuki Ashikari, Makoto Matsuoka, Chiharu Ueguchi,
Summary Although the shoot apical meristem (SAM) is ultimately responsible for post‐embryonic development in higher plants, lateral meristems also play an important role in determining the final morphology of the above‐ground part. Axillary buds developing at the axils of leaves produce additional shoot systems, lateral branches. The rice TB1 gene ( OsTB1 ) was first identified based on its sequence similarity with maize TEOSINTE BRANCHED 1 ( TB1 ), which is involved in lateral branching in maize. Both genes ...
Tópico(s): Plant tissue culture and regeneration
2003 - Wiley | The Plant Journal
Taroh Satoh, Takashi Ura, Yasuhide Yamada, Kentaro Yamazaki, Toshimasa Tsujinaka, Masaki Munakata, Tomohiro Nishina, Shu Okamura, Taito Esaki, Yasutsuna Sasaki, Wasaburo Koizumi, Yoshihiro Kakeji, Naoki Ishizuka, Ichinosuke Hyodo, Yuh Sakata,
Irinotecan-induced severe neutropenia is associated with homozygosity for the UGT1A1*28 or UGT1A1*6 alleles. In this study, we determined the maximum-tolerated dose (MTD) of irinotecan in patients with UGT1A1 polymorphisms. Patients who had received chemotherapy other than irinotecan for metastatic gastrointestinal cancer were enrolled. Patients were divided into three groups according to UGT1A1 genotypes: wild-type (*1/*1); heterozygous (*28/*1, *6/*1); or homozygous (*28/*28, *6/*6, *28/*6). Irinotecan ...
Tópico(s): Lung Cancer Research Studies
2011 - Wiley | Cancer Science
Taito Murakami, Yusuke Nambu, Takashi Koretsune, Gu Xiangyu, Takafumi Yamamoto, Craig M. Brown, Hiroshi Kageyama,
Magnetic properties of MnSb2Te4 were examined through magnetic susceptibility, specific-heat, and neutron-diffraction measurements. As opposed to isostructural MnBi2Te4 with the antiferromagnetic ground state, MnSb2Te4 develops a spontaneous magnetization below 25 K. From our first-principles calculations on the material in a ferromagnetic state, the state could be interpreted as a type-II Weyl semimetal state with broken time-reversal symmetry. Detailed structural refinements using x-ray-diffraction ...
Tópico(s): Heusler alloys: electronic and magnetic properties
2019 - American Physical Society | Physical review. B./Physical review. B
Norihiko Iida, Takayuki Tsuboi,
... TSUBOI MD Department of Environmental and Public Health, Taito City, Tokyo, JapanSearch for more papers by this ... TSUBOI MD Department of Environmental and Public Health, Taito City, Tokyo, JapanSearch for more papers by this ...
Tópico(s): Genomic variations and chromosomal abnormalities
1995 - Wiley | Psychiatry and Clinical Neurosciences
Yusuke Kawamura, Kenji Ikeda, Yasuji Arase, Yushi Sorin, Taito Fukushima, Hideo Kunimoto, Tetsuya Hosaka, Masahiro Kobayashi, Satoshi Saitoh, Hitomi Sezaki, Norio Akuta, Fumitaka Suzuki, Yoshiyuki Suzuki, Hiromitsu Kumada,
Currently, non-alcoholic steatohepatitis (NASH) can only be diagnosed histopathologically. Our objective was to establish a new scoring system for the fibrotic stage of NASH.We enrolled 139 patients with histologically proven NASH and divided them into two groups to construct (n = 90) and validate (n = 49) a fibrotic score for NASH (FSN). We used 17 variables and their natural logarithmic transformations in the multivariate analysis. To assess the accuracy of the FSN in determining NASH advanced fibrosis ( ...
Tópico(s): Lipid metabolism and disorders
2015 - Springer Science+Business Media | Hepatology International
Muneyoshi IYOTA, T. Matsuda, Tomokazu Sano, Masaya SHIGETA, Takahisa Shobu, Hirokatsu Yumoto, Takahisa Koyama, Hiroshi Yamazaki, Yasunori Senba, Haruhiko Ohashi, Shunji Goto, Ichiro Inoue, Yujiro Hayashi, Kenji Tamasaku, Taito Osaka, Jumpei Yamada, Makina Yabashi,
Aluminum alloys are increasingly being applied to automobile bodies to reduce the weight of automobiles. In joining steel materials and aluminum alloys using resistance spot welding(RSW), it is important to control the state of intermetallic compounds due to the temperature at the joining interface. In other words, in RSW of Fe/Al dissimilar materials, it is necessary to clarify the heating and cooling phenomena of the interface temperature during joining. Although the convection behavior of the ...
Tópico(s): Aluminum Alloy Microstructure Properties
2023 - Elsevier BV | Journal of Manufacturing Processes
Satoshi Kobayashi, Taito Fukushima, Makoto Ueno, Satoshi Moriya, Makoto Chuma, Kazushi Numata, Kota Tsuruya, Shunji Hirose, Tatehiro Kagawa, Nobuhiro Hattori, Tsunamasa Watanabe, Kotaro Matsunaga, Michihiro Suzuki, Haruki Uojima, Hisashi Hidaka, Chika Kusano, Motoko Suzuki, Manabu Morimoto,
Abstract Background Transarterial chemoembolization (TACE) is the standard treatment for intermediate stage hepatocellular carcinoma (HCC) (Barcelona Clinic Liver Cancer [BCLC] B). However, it often leads to a poor prognosis and decreased hepatic function especially in patients with BCLC substage B2. Lenvatinib (LEN) was demonstrated to be efficacious in these patients in the REFLECT phase 3 trial. We therefore aimed to evaluate the efficacy and safety of LEN as a first-line treatment for the patients ...
Tópico(s): Cholangiocarcinoma and Gallbladder Cancer Studies
2022 - BioMed Central | BMC Cancer
Gerhard Jung, Eva Hernández‐Illán, Juan José Lozano, Julia Sidorova, Jenifer Muñoz, Yasuyuki Okada, Enrique Quintero, Goretti Hernández, Rodrigo Jover, Sabela Carballal, Míriam Cuatrecasas, Lorena Moreno, Mireia Díaz, Teresa Ocaña, Ariadna Sánchez, Liseth Rivero, Oswaldo Ortíz, Joan Llach, Antoni Castells, María Pellisé, Ajay Goel, Eduard Batlle, Francesc Balaguer,
... ng Hb/mL; OC-SENSOR; Eiken Chemical Co., Taito-ku, Tokyo, Japan), a colonoscopy is performed. In ...
Tópico(s): Colorectal Cancer Screening and Detection
2022 - Elsevier BV | Journal of Molecular Diagnostics
Yoshiaki Ito, Osamu Ikeda, Rintaro Ban, Taito Kubota, Tatsuya Sakamaki, Takahiro Kuribayashi, Akio Suzuki,
In-situ X-ray diffraction measurements of ScOOH were conducted under high pressure and temperature conditions up to 11 GPa and 900 K to understand its phase transitions. As the pressure increased, α-ScOOH, InOOH-type ScOOH, and YbOOH-type ScOOH were observed. The experimental results indicate that the boundaries between α-ScOOH and InOOH-type ScOOH, and between InOOH-type and YbOOH-type ScOOH are represented by the following linear equations: P(GPa) = (0.0009 ± 0.0015) × [T(K) – 700] + 4.33 ± 0.04 and P(GPa) = (– ...
Tópico(s): Crystal Structures and Properties
2021 - Taylor & Francis | High Pressure Research
... Edogawa-ku; the latter -Bunkyo-ku, Arakawa-ku, Taito-ku, Sumida-ku, and Koto-ku-are in ...
Tópico(s): Urban and spatial planning
1994 - Association of Japanese Geographers | Geographical Review of Japan
Naotake Akutsu, Tomoaki Karube, Shinichi Miyazaki, Taito Aoki, Kenji Nakajima, Takashi Akai, Masaya Uesato, Yoshihiro Ishikawa, Nobuo Hirayama, Fumihiko Miura, Hideaki Hayashi, Y Gunji, Takenori Ochiai,
Objective: Endoscopic ultrasonography (EUS) is thought to be a useful tool for accurate preoperative staging of patients with gastric carcinomas, especially essential for determining patient selection for potentially curative resection, curative endoscopic mucosal resection (EMR), or non-curative operation. In this presentation, we report our experience with two types of EUS (the rotating sector echoendoscope [RS] and the linear sector echoendoscope [LS]) and discuss the accuracy with these EUS. Methods: ...
Tópico(s): Gastrointestinal Tumor Research and Treatment
2003 - Elsevier BV | Ultrasound in Medicine & Biology