Soichi Ogishima, Satoshi Nagaie, Satoshi Mizuno, Ryosuke Ishiwata, Keita Iida, Kazuro Shimokawa, Takako Takai‐Igarashi, Naoki Nakamura, Sachiko Nagase, Tomohiro Nakamura, Naho Tsuchiya, Naoki Nakaya, Keiko Murakami, Fumihiko Ueno, Tomomi Onuma, Mami Ishikuro, Taku Obara, Shunji Mugikura, Hiroaki Tomita, Akira Uruno, Tomoko Kobayashi, Akito Tsuboi, Shu Tadaka, Fumiki Katsuoka, Akira Narita, Mika Sakurai, Satoshi Makino, Gen Tamiya, Yuichi Aoki, Ritsuko Shimizu, Ikuko N. Motoike, S. Koshiba, Naoko Minegishi, Kazuki Kumada, Takahiro Nobukuni, Kichiya Suzuki, Inaho Danjoh, Fuji Nagami, Kozo Tanno, Hideki Ohmomo, Koichi Asahi, Atsushi Shimizu, Atsushi Hozawa, Shinichi Kuriyama, Masayuki Yamamoto, Michiaki Abe, Yayoi Aizawa, Yuichi Aoki, Koichi Chida, Inaho Danjoh, Shinichi Egawa, Ai Eto, Takamitsu Funayama, Nobuo Fuse, Yohei Hamanaka, Yuki Harada, Hiroaki Hashizume, Shinichi Higuchi, Sachiko Hirano, Takumi Hirata, Masahiro Hiratsuka, Atsushi Hozawa, Kazuhiko Igarashi, Jin Inoue, N. Ishida, Naoto Ishii, Tadashi Ishii, Mami Ishikuro, Kiyoshi Ito, Sadayoshi Ito, Maiko Kageyama, Fumiki Katsuoka, Hiroshi Kawame, Junko Kawashima, Masahiro Kikuya, Kengo Kinoshita, Kazuyuki Kitatani, Tomomi Kiyama, Hideyasu Kiyomoto, Tomoko Kobayashi, Eiichi Kodama, Mana Kogure, Kaname Kojima, Sachie Koreeda, S. Koshiba, Shihoko Koyama, Hisaaki Kudo, Kazuki Kumada, Shigeo Kure, Miho Kuriki, Shinichi Kuriyama, Yoko Kuroki, Norihide Maikusa, Satoshi Makino, Hiroko Matsubara, Hiroyuki Matsui, Hirohito Metoki, Takahiro Mimori, Naoko Minegishi, Kazuharu Misawa, Masako Miyashita, Satoshi Mizuno, Hozumi Motohashi, Ikuko N. Motoike, Satoshi Nagaie, Masato Nagai, Fuji Nagami, Masao Nagasaki, Sachiko Nagase, Naoki Nakamura, Tomohiro Nakamura, Naoki Nakaya, Keiko Nakayama, Akira Narita, Ichiko Nishijima, Takahiro Nobukuni, Kotaro Nochioka, Taku Obara, Soichi Ogishima, Noriaki Ohuchi, G. Olivier, Noriko Osumi, Hiroshi Otsu, Akihito Otsuki, Daisuke Saigusa, Sakae Saito, Tomo Saito, Masaki Sakaida, Mika Sakurai‐Yageta, Yuki Sato, Yukuto Sato, Atsushi Sekiguchi, Chen‐Yang Shen, Tomoko Shibata, Ritsuko Shimizu, Kazuro Shimokawa, Matsuyuki Shirota, Junichi Sugawara, Kichiya Suzuki, Yoichi Suzuki, Shu Tadaka, Makiko Taira, Takako Takai‐Igarashi, Yuji Takano, Yasuyuki Taki, Gen Tamiya, Osamu Tanabe, Hiroshi Tanaka, Yukari Tanaka, Shunsuke Teraguchi, Takahiro Terakawa, Teiji Tominaga, Hiroaki Tomita, Akito Tsuboi, Naho Tsuchiya, Ichiro Tsuji, Masao Ueki, Akira Uruno, Nobuo Yaegashi, Junya Yamagishi, Yumi Yamaguchi‐Kabata, Chizuru Yamanaka, Riu Yamashita, Jun Yasuda, Junji Yokozawa, Kazunori Waki, Makoto Sasaki, Junko Akai, Ryujin Endo, Akimune Fukushima, Ryohei Furukawa, Tsuyoshi Hachiya, Kouhei Hashizume, Jiro Hitomi, Yasushi Ishigaki, Shohei Komaki, Yuka Kotozaki, Takahiro Mikami, Motoyuki Nakamura, Naoyuki Nishiya, Satoshi Nishizuka, Yoko Nomura, Kuniaki Ogasawara, Hideki Ohmomo, Shinichi Omama, Ryo Otomo, Kotaro Otsuka, Kotaro Oyama, Kiyomi Sakata, Ryohei Sasaki, Mamoru Satoh, Namie Sato, Atsushi Shimizu, Yu Shiwa, Yoichi Sutoh, Nobuyuki Takanashi, Noriko Takebe, Fumitaka Tanaka, Ryoichi Tanaka, Kozo Tanno, Tomoharu Tokutomi, Kayono Yamamoto, Fumio Yamashita, Nobuo Fuse, Teiji Tominaga, Shigeo Kure, Nobuo Yaegashi, Kengo Kinoshita, Makoto Sasaki, Hiroshi Tanaka, Masayuki Yamamoto,
To reveal gene-environment interactions underlying common diseases and estimate the risk for common diseases, the Tohoku Medical Megabank (TMM) project has conducted prospective cohort studies and genomic and multiomics analyses. To establish an integrated biobank, we developed an integrated database called "dbTMM" that incorporates both the individual cohort/clinical data and the genome/multiomics data of 157,191 participants in the Tohoku Medical Megabank project. To our knowledge, dbTMM is the ...
Tópico(s): Health, Environment, Cognitive Aging
2021 - Springer Nature | Human Genome Variation
Naoko Minegishi, Ichiko Nishijima, Takahiro Nobukuni, Hisaaki Kudo, N. Ishida, Takahiro Terakawa, Kazuki Kumada, Riu Yamashita, Fumiki Katsuoka, Soichi Ogishima, Kichiya Suzuki, Makoto Sasaki, Mamoru Satoh, Masayuki Yamamoto,
The Tohoku Medical Megabank biobank (TMM biobank) is the first major population-based biobank established in Japan. The TMM biobank was established based on two population cohorts and is a reconstruction program from the Great East Japan Earthquake and Tsunami of 2011. The biobank stores more than 3.4 million tubes of biospecimens and associated health and analytic data obtained from approximately 150,000 TMM cohort participants between May 2013 and December 2018, and the TMM biobank currently shares ...
Tópico(s): Genomics and Rare Diseases
2019 - Tohoku University | The Tohoku Journal of Experimental Medicine
Ryutaro Tanizaki, Takeshi Nishijima, Takahiro Aoki, Katsuji Teruya, Yoshimi Kikuchi, Shinichi Oka, Hiroyuki Gatanaga,
Background. Intramuscular benzathine penicillin G (BPG) is widely used for the treatment of syphilis. However, BPG is not available in some countries. This study examined the effectiveness and safety of high-dose oral amoxicillin plus probenecid for the treatment of syphilis in patients with human immunodeficiency virus type 1 (HIV-1). Methods. This retrospective observational study included 286 HIV-infected male patients with syphilis (median age, 36 years; median CD4 count, 389 cells/µL) who were ...
Tópico(s): HIV, Drug Use, Sexual Risk
2015 - Oxford University Press | Clinical Infectious Diseases
Hironobu Nishijima, Takahiro Asakage, Masashi Sugasawa,
Carotid body tumors (CBTs) are rare neoplasms of the carotid body. Most CBTs are benign; however, some can show malignant behavior. Malignant CBTs have an unpredictable history; often, there is no correlation between the histologic findings and the clinical behavior. They are usually diagnosed by the development of local recurrence or lymph node metastasis following total resection of the primary mass, or by the detection of distant metastasis. There are few reports of histopathologic confirmation ...
Tópico(s): Cancer, Hypoxia, and Metabolism
2011 - SAGE Publishing | Annals of Otology Rhinology & Laryngology
Satoshi Iwata, Hiroshi Kobayashi, Rikako Miyake-Nishijima, Takahiro Sasaki, Akiko Souta-Kuribara, Mamoru Nori, Osamu Hosono, Hiroshi Kawasaki, Hirotoshi Tanaka, Chikao Morimoto,
CD82, a member of tetraspan family (tetraspanin), is a multifunctional molecule that is involved in cell activation, costimulation, and cell spreading of T cells. Here we show that immobilized anti-CD82 monoclonal antibody (mAb) as well as anti-alpha4beta1 integrin mAb induced tyrosine phosphorylation of pp105/Crk-associated substrate lymphocyte type (Cas-L) in human peripheral T cells and H9 cells. Furthermore, one of anti-CD82 mAb (8E4), which induces homotypic aggregation of T cells and H9 cells ...
Tópico(s): Immunotherapy and Immune Responses
2002 - Wiley | European Journal of Immunology
Kazumi Takahashi, Takahide Hayano, Ryota Sugimoto, Hirofumi Kashiwagi, Shinoda Mari, Yoshihiro Nishijima, Takahiro Suzuki, Shingo Suzuki, Yuko Ohnuki, Akane Kondo, Takashi Shiina, Hirofumi Nakaoka, Ituro Inoue, Shun‐ichiro Izumi,
Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is characterized by congenital absence of the vagina and uterus. We conducted genome-wide SNP analyses and exome sequencing to detect the causes of MRKH syndrome. We identified de novo variants of MYCBP2, NAV3, and PTPN3 in three families and a variant of MYCBP2 in a sporadic case. Here, we demonstrated the partial genetic makeup of Japanese MRKH syndrome.
Tópico(s): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
2018 - Springer Nature | Human Genome Variation
Masahiko Higashiyama, Yasuo Miyoshi, Ken Kodama, Hideoki Yokouchi, Kaoru Takami, Masaki Nishijima, Takahiro Nakayama, H Kobayashi, Kazuhiko Minamigawa, Yusuke Nakamura,
Tópico(s): Lung Cancer Research Studies
2000 - Elsevier BV | European Journal of Cancer
Chinami Makii, Yuji Ikeda, Katsutoshi Oda, Yuriko Uehara, Akira Nishijima, Takahiro Koso, Yoshiko Kawata, Tomoko Kashiyama, Aki Miyasaka, Kenbun Sone, Michihiro Tanikawa, Tetsushi Tsuruga, Mayuyo Mori‐Uchino, Kazunori Nagasaka, Yōko Matsumoto, Osamu Wada‐Hiraike, Kei Kawana, Kosei Hasegawa, Keiichi Fujiwara, Hiroyuki Aburatani, Yutaka Osuga, Tomoyuki Fujii,
PI3K pathway signaling has received attention as a molecular target in clear cell ovarian carcinoma (CCOC). MDM2 is one of the AKT effectors in the PI3K pathway, which binds to and degrades p53. In this study, we aimed to clarify the prognostic significance of PIK3CA and MDM2 expression, and potential therapeutic effect of a dual inhibition of the PI3K pathway and MDM2.cDNA expression was evaluated by using microarray data using 75 samples of CCOC. DS-7423 (dual inhibitor of pan-PI3K and mTOR) and ...
Tópico(s): Microtubule and mitosis dynamics
2019 - Elsevier BV | Gynecologic Oncology
Motoyuki Tsuboi, Takeshi Nishijima, Takahiro Aoki, Katsuji Teruya, Yoshimi Kikuchi, Hiroyuki Gatanaga, Shinichi Oka,
The usefulness of an automated latex turbidimetric rapid plasma reagin (RPR) assay, compared to the conventional manual card test (serial 2-fold dilution method), for the diagnosis of syphilis and evaluation of treatment response remains unknown. We conducted (i) a cross-sectional study and (ii) a prospective cohort study to elucidate the correlation between automated and manual tests and whether a 4-fold decrement is a feasible criterion for successful treatment with the automated test, respectively, ...
Tópico(s): HIV/AIDS Research and Interventions
2018 - American Society for Microbiology | Journal of Clinical Microbiology
Takahiko Nishijima, Takahiro Nakano, Shinji Takahashi, Koya Suzuki, Hiroshi Yamada, Shohei Kokudo, Seiji Ohsawa,
The purpose of this study was to analyze the relationship between changes over the years in physical abilities of young people and their exercise and sports activity statistically. Samples were 17-year-olds covered in the National Statistics on Physical Fitness and Motor Ability prepared by MEXT obtained through Sports-test during the 18 years between 1980 and 1997. Changes over the years in averages of total physical fitness test scores was statistically analyzed by gender and groups divided by ...
Tópico(s): Sports Performance and Training
2003 - | International Journal of Sport and Health Science
Akio Nishijima, Takahiro Fujimoto, Takamichi Hirata, Junko Nishijima,
Cold atmospheric pressure plasma (CAP) has been expected to be effective for wound healing among plasma medicines and has been attracting attention. The aim of this retrospective clinical study was to evaluate and compare the effects of CAP on acute wounds created by a fractional CO2 (FXCO2) laser on four treatment groups. Methods: This study was conducted between September 2017 and November 2018. Radiated surface wounds were created using a FXCO2 laser on four identically-sized regions on the medial ...
Tópico(s): Laser Applications in Dentistry and Medicine
2019 - Scientific Research Publishing | Modern Plastic Surgery
Chinami Makii, Katsutoshi Oda, Yuji Ikeda, Kenbun Sone, Kosei Hasegawa, Yuriko Uehara, Akira Nishijima, Kayo Asada, Takahiro Koso, Tomohiko Fukuda, Kanako Inaba, Shinya Oki, Hidenori Machino, Machiko Kojima, Tomoko Kashiyama, Mayuyo Mori‐Uchino, Takahide Arimoto, Osamu Wada‐Hiraike, Kei Kawana, Tetsu Yano, Keiichi Fujiwara, Hiroyuki Aburatani, Yutaka Osuga, Tomoyuki Fujii,
... Kosei Hasegawa 2 , Yuriko Uehara 1, 3 , Akira Nishijima 1, 3 , Kayo Asada 1, 3 , Takahiro Koso 1, 3 , Tomohiko Fukuda 1 , Kanako Inaba ...
Tópico(s): Viral-associated cancers and disorders
2016 - Impact Journals LLC | Oncotarget
Y. Kasahara, Takahiro Nishijima, Tatsuya Sato, Yuki Takeuchi, Jianting Ye, Hongtao Yuan, Hidekazu Shimotani, Yoshihiro Iwasa,
We report evidence for superconductivity induced by the application of strong electric fields onto the surface of a band insulator, ZrNCl, provided by the observation of a shielding diamagnetic signal. We introduced an electric-double-layer capacitor configuration and in situ magnetization measurements at low temperatures as a method to detect the novel electric-field-induced superconducting state. The results showed excellent agreement with a previous report using a transistor configuration, demonstrating ...
Tópico(s): Inorganic Chemistry and Materials
2011 - Physical Society of Japan | Journal of the Physical Society of Japan
Mai Furumiya, Katsuhisa Inoue, Chihiro Nishijima, Takahiro Yamashiro, Erina Inaoka, Kinya Ohta, Yayoi Hayashi, Hiroaki Yuasa,
Myricetin is a flavonoid that has recently been suggested to interfere with the intestinal folate transport system. The present study was conducted to examine that possibility, focusing on its inhibitory effect on proton-coupled folate transporter (PCFT) as the molecular entity of the transport system. The uptake transport of folate was first examined in the Caco-2 cell as an intestinal epithelial cell model, and its carrier-mediated component, of which the Michaelis constant (Km) was 0.407 μΜ, was ...
Tópico(s): Phytase and its Applications
2014 - Elsevier BV | Drug Metabolism and Pharmacokinetics
Hidekazu Nishigori, Taku Obara, Toshie Nishigori, Hirohito Metoki, Mami Ishikuro, Satoshi Mizuno, Kasumi Sakurai, Nozomi Tatsuta, Ichiko Nishijima, Ikuma Fujiwara, Takahiro Arima, Kunihiko Nakai, Nariyasu Mano, Shinichi Kuriyama, Nobuo Yaegashi,
Purpose: To elucidate drug use before and during pregnancy in Japan. Methods: The Japan Environment and Children’s Study (JECS) is an ongoing nationwide birth cohort study. We analyzed data from JECS involving cases where drugs were used for 12 months before pregnancy was diagnosed, between the time of diagnosis of pregnancy until week 12 of pregnancy, and after week 12 of pregnancy. Results: We analyzed data from 97,464 pregnant women. The percentages of pregnant women who had taken one or more ...
Tópico(s): Pregnancy and preeclampsia studies
2017 - Multidisciplinary Digital Publishing Institute | Pharmacy
Satoshi Mizuno, Hidekazu Nishigori, Takashi Sugiyama, Fumiaki Takahashi, Noriyuki Iwama, Zen Watanabe, Kasumi Sakurai, Mami Ishikuro, Taku Obara, Nozomi Tatsuta, Ichiko Nishijima, Ikuma Fujiwara, Takahiro Arima, Shinichi Kuriyama, Hirohito Metoki, Kunihiko Nakai, Hidekuni Inadera, Nobuo Yaegashi,
Social capital is generally defined as the quality and frequency of social interactions with relatives, neighbors, and society. Social capital refers to broad concepts of social interactions and structures in individuals, communities and societies such as trust (e.g., neighborhood trust, which is social cohesion with neighbors) and social support (e.g., emotional support, which is the level of the feeling of being loved). Studies during the last few decades have shown that there is a significant inverse ...
Tópico(s): Diabetes Management and Education
2016 - Elsevier BV | Diabetes Research and Clinical Practice
T. Kobayashi, Takeshi Nishijima, Katsuji Teruya, Takahiro Aoki, Yoshimi Kikuchi, Shinichi Oka, Hiroyuki Gatanaga,
Background Little information is available on the mortality and risk factors associated with death in disseminated non-tuberculous mycobacterial infection (dNTM) in HIV-infected patients in the ART-era. Methods In a single-center study, HIV-infected dNTM with positive NTM culture from sterile sites between 2000 and 2013 were analysed. The clinical characteristics at commencement of anti-mycobacterial treatment (baseline) were compared between those who survived and died. Results Twenty-four patients ...
Tópico(s): Diagnosis and treatment of tuberculosis
2016 - Public Library of Science | PLoS ONE
Akihito Uji, Tomoaki Murakami, Kazuaki Nishijima, Tadamichi Akagi, Takahiro Horii, Naoko Arakawa, Yuki Muraoka, Abdallah A. Ellabban, Nagahisa Yoshimura,
To determine if hyperreflective foci in the outer retina are associated with photoreceptor integrity and the logarithm of minimal angle of resolution (logMAR) visual acuity (VA) in patients with diabetic macular edema (DME).Retrospective, observational, cross-sectional study.Patients (n=76; 108 eyes) with clinically relevant macular edema and no serous retinal detachment were analyzed retrospectively. Spectral-domain optical coherence tomography (SD-OCT) images were obtained for all patients. We investigated ...
Tópico(s): Glaucoma and retinal disorders
2011 - Elsevier BV | American Journal of Ophthalmology
Yasuki Matsuda, Michio Ogawa, Kiyoshi Sakamoto, Shin-ichi Yamashita, A. Kanda, Masaki KOHNO, Nobuo Yoshida, Junichi Nishijima, Asako Murata, Takahiro Mori,
A radioimmunoassay (RIA) for the determination of human group-II phospholipase A(2) (M-PLA(2)) has been developed. M-PLA(2) was purified from human spleen. Monoclonal antibody (IgG) was prepared by fusion of splenic cells from immunized mice with M-PLA(2) and the mouse myeloma cell line NS-1. The RIA was carried out by a single antibody method. The assay is sensitive (0.78 μg/1), reproducible and specific. In healthy individuals, the serum M-PLA2 concentration ranges from 1.4 to 4.2 μg/l, the average ...
Tópico(s): Peptidase Inhibition and Analysis
1991 - Karger Publishers | Enzyme
Tomoaki Murakami, Naoko Ueda‐Arakawa, Kazuaki Nishijima, Akihito Uji, Takahiro Horii, Ken Ogino, Nagahisa Yoshimura,
To integrate parameters on spectral-domain optical coherence tomography (SD-OCT) in diabetic retinopathy (DR) based on the self-organizing map and objectively describe the macular morphologic patterns.A total of 336 consecutive eyes of 216 patients with DR for whom clear SD-OCT images were available were retrospectively reviewed. Eleven OCT parameters and the logarithm of the minimal angle of resolution (logMAR) were measured. These multidimensional data were analyzed based on the self-organizing map ...
Tópico(s): Glaucoma and retinal disorders
2014 - Cadmus Press | Investigative Ophthalmology & Visual Science
T. Kunihisa, Shinji Yamamoto, Masaaki Nishijima, Takahiro Yokoyama, M. Nishitsuji, K. Nishii, Osamu Ishikawa,
This paper describes the power amplifier used for an automated toll collection system in Japan
Tópico(s): Advanced Power Amplifier Design
1999 - Institute of Electronics, Information and Communication Engineers | IEICE Transactions on Electronics
Shôji Watanabe, Kosuke Nakaema, Takahiro Nishijima, Akiko Okamoto, Noriyuki Yonezawa,
In the title compound, C(19)H(15)NO(5), the dihedral angle between the naphthalene ring system and the benzene ring is 61.97 (5)°. The dihedral between the naphthalene ring system and the bridging carbonyl C-C(=O)-C plane is 54.68 (6)°, far larger than that [12.54 (7)°] between the phenyl group and the bridging carbonyl group. The nitro group and the phenyl ring are almost coplanar [O-N-C-C torsion angle = 2.94 (19)°]. In the crystal, mol-ecules are linked by C-H⋯π inter-actions and the phenyl rings are ...
Tópico(s): Structural and Chemical Analysis of Organic and Inorganic Compounds
2010 - International Union of Crystallography | Acta Crystallographica Section E Structure Reports Online
Naotoshi Yamashita, Yasunori Nakayama, Kei Tsumura, Takahiro Nishijima, Hiroyasu Ueda, Kiyomichi Yoshimaru, Tomoshige Hayashi, Junichi Yoshikawa,
Objectives The purpose of this study was to evaluate whether the pulsatility of brachial artery pressure is related to an increased risk of coronary artery disease (CAD). On the basis of vascular mechanics, we recently reported that relative pulse pressure can predict the occurrence of restenosis after percutaneous transluminal coronary angioplasty. We also hypothesized that relative pulse pressure of the brachial arterial pressure waveform is associated with an increased risk of CAD. Design A cross- ...
Tópico(s): Coronary Interventions and Diagnostics
2001 - Lippincott Williams & Wilkins | Journal of Hypertension
Mizuki Sugiyama, Ichiko Nishijima, Shota Miyazaki, Takahiro J. Nakamura,
In mammals, the timing of behavior and physiological activity is controlled by the suprachiasmatic nucleus (SCN) in the hypothalamus. Incidentally, secretin is a peptide hormone that promotes digestive activities and regulates water reabsorption. In recent studies, exogenous administration of secretin has been reported to induce secretion of oxytocin in the supraoptic nucleus of the hypothalamus and modulate social behavior. These results indicate that secretin is involved in the neural network that ...
Tópico(s): Sleep and Wakefulness Research
2020 - Elsevier BV | Neuroscience Letters
Tomofumi Ishikawa, Taku Obara, Hidekazu Nishigori, Toshie Nishigori, Hirohito Metoki, Mami Ishikuro, Nozomi Tatsuta, Satoshi Mizuno, Kasumi Sakurai, Ichiko Nishijima, Yuriko Murai, Ikuma Fujiwara, Takahiro Arima, Kunihiko Nakai, Nobuo Yaegashi, Shinichi Kuriyama, Nariyasu Mano,
Objective: To provide the latest and most promising evidence on the prevalence and determinants for folic acid supplementation in pregnant women in Japan, including differences in prevalence between interview years and determinants across regions.Materials and methods: The study participants were enrolled from 15 regional centers across Japan between January 2011 and March 2014. Information on the use of folic acid supplementation before and during pregnancy and the characteristics of the participants ...
Tópico(s): Pregnancy and preeclampsia studies
2018 - Informa | The Journal of Maternal-Fetal & Neonatal Medicine
Kasumi Sakurai, Hidekazu Nishigori, Toshie Nishigori, Satoshi Mizuno, Taku Obara, Noriyuki Iwama, Zen Watanabe, Mami Ishikuro, Nozomi Tatsuta, Ichiko Nishijima, Junichi Sugawara, Ikuma Fujiwara, Takahiro Arima, Shinichi Kuriyama, Hirohito Metoki, Fumiaki Takahashi, Kunihiko Nakai, Nobuo Yaegashi,
Abstract Objective This study aimed to clarify the correlation between the 2011 Great East Japan Earthquake and domestic violence (DV) against pregnant females after the disaster in Miyagi Prefecture, an area damaged by the earthquake and tsunami. Methods We analyzed 7600 pregnant females from June to December 2011. The incidence of physical and mental DV and the proportions in the inland, north coastal, and south coastal areas of Miyagi Prefecture and nationwide were calculated, and a chi-square ...
Tópico(s): Homelessness and Social Issues
2016 - Cambridge University Press | Disaster Medicine and Public Health Preparedness
Taku Obara, Hidekazu Nishigori, Toshie Nishigori, Hirohito Metoki, Mami Ishikuro, Nozomi Tatsuta, Satoshi Mizuno, Kasumi Sakurai, Ichiko Nishijima, Yuriko Murai, Ikuma Fujiwara, Takahiro Arima, Kunihiko Nakai, Nariyasu Mano, Nobuo Yaegashi, Shinichi Kuriyama,
The aim of the study was to clarify the prevalence and determinants of inadequate use of folic acid supplementation in pregnant Japanese women.This study was part of the Japan Environment and Children's Study, a nationwide and government-funded birth cohort study. We collected information on the use of folic acid supplementation before and during pregnancy and characteristics of participants using self-administered questionnaire.Among 9849 women who completed the data collection for this study, ...
Tópico(s): Pregnancy and Medication Impact
2016 - Informa | The Journal of Maternal-Fetal & Neonatal Medicine
Zen Watanabe, Noriyuki Iwama, Hidekazu Nishigori, Toshie Nishigori, Satoshi Mizuno, Kasumi Sakurai, Mami Ishikuro, Taku Obara, Nozomi Tatsuta, Ichiko Nishijima, Ikuma Fujiwara, Kunihiko Nakai, Takahiro Arima, Takashi Takeda, Junichi Sugawara, Shinichi Kuriyama, Hirohito Metoki, Nobuo Yaegashi,
To examine psychological distress among pregnant women in Miyagi prefecture which was directly affected by the Great East Japan Earthquake and tsunami and compare other areas of Japan that were less damaged. This study was conducted in conjunction with the Japan Environment and Children's Study (JECS). We examined 10,129 Japanese women using the primary fixed data of the JECS. The Kessler 6-item psychological distress scale (K6) was administered to 7473 eligible women including 998 in Miyagi unit ...
Tópico(s): Grief, Bereavement, and Mental Health
2015 - Elsevier BV | Journal of Affective Disorders
Ei Kinai, Takeshi Nishijima, Daisuke Mizushima, Kôji Watanabe, Takahiro Aoki, Haruhito Honda, Hirohisa Yazaki, Ikumi Genka, Junko Tanuma, Katsuji Teruya, Kunihisa Tsukada, Hiroyuki Gatanaga, Yoshimi Kikuchi, Shinichi Oka,
HIV-infected patients are at high risk for bone mineral density (BMD) loss. The present study was designed to provide information on characteristics of BMD abnormalities in Japanese HIV-1-infected patients and risk factors involved in worsening of BMD. A total of 184 Japanese HIV-1-infected men were studied with a dual-energy X-ray absorptiometry scan (DXA) at the lumbar spine and femoral neck. Multivariate logistic regression models were used for comparison of the impact of risk factors on BMD loss. ...
Tópico(s): HIV/AIDS drug development and treatment
2014 - Mary Ann Liebert, Inc. | AIDS Research and Human Retroviruses
Munemitsu Yoshikawa, Tomoaki Murakami, Kazuaki Nishijima, Akihito Uji, Ken Ogino, Takahiro Horii, Nagahisa Yoshimura,
To investigate the papillofoveal distance and its association with retinal thickness on optical coherence tomography (OCT) images after vitrectomy for diabetic macular edema (DME).In this retrospective case series, 72 eyes of 57 consecutive patients who underwent vitrectomy for DME were included. Retinal images dissecting the fovea horizontally were obtained using OCT before and after vitrectomy. After identification of the disc margin and the presumed foveal center, the papillofoveal distance was ...
Tópico(s): Glaucoma and retinal disorders
2013 - Cadmus Press | Investigative Ophthalmology & Visual Science