Guy Perrieère, Manolo Gouy, Takashi Gojobori,
... author on: Oxford Academic PubMed Google Scholar Takashi Gojobori Takashi Gojobori 1DNA Research Center, National Institute of GeneticsMishima, Shizuoka- ...
Tópico(s): Bacteriophages and microbial interactions
1994 - Oxford University Press | Nucleic Acids Research
K. Suzuki, M. Mizokami, Johnson Y.N. Lau, Naoto Mizoguchi, Koji Kato, Y Mizuno, T Sodeyama, Kendo Kiyosawa, Takashi Gojobori,
... author on: Oxford Academic PubMed Google Scholar Takashi Gojobori Takashi Gojobori Search for other works by this author on: ...
Tópico(s): Vibrio bacteria research studies
1994 - Oxford University Press | The Journal of Infectious Diseases
Toshitsugu Sato, Mahito Terabe, Hiroshi Watanabe, Takashi Gojobori, C. Hori-Takemoto, K.-i. Miura,
... author on: Oxford Academic PubMed Google Scholar Takashi Gojobori, Takashi Gojobori ‡Center for Information Biology, National Institute of Genetics1111 ...
Tópico(s): Genomics and Phylogenetic Studies
2001 - Oxford University Press | The Journal of Biochemistry
K.-n. Wada, Y. Wada, F. Ishibashi, T. Gojobori, Toshimichi Ikemura,
... author on: Oxford Academic PubMed Google Scholar Takashi Gojobori, Takashi Gojobori Search for other works by this author on: ...
Tópico(s): RNA modifications and cancer
1992 - Oxford University Press | Nucleic Acids Research
T. Maruyama, T. Gojobori, S.-i. Aota, Toshimichi Ikemura,
... author on: Oxford Academic PubMed Google Scholar Takashi Gojobori, Takashi Gojobori National Institute of GeneticsMishima 411, Japan Search for ...
Tópico(s): Cancer-related molecular mechanisms research
1986 - Oxford University Press | Nucleic Acids Research
S.-i. Aota, T. Gojobori, Fumie Ishibashi, T. Maruyama, Toshimichi Ikemura,
... author on: Oxford Academic PubMed Google Scholar Takashi Gojobori, Takashi Gojobori National Institute of GeneticsMishmia, 411, Japan Search for ...
Tópico(s): RNA modifications and cancer
1988 - Oxford University Press | Nucleic Acids Research
... Xiao-Juan Zhang, Li Zhou, Jian-Fang Gui, Takashi Gojobori Whole Genome Incorporation and Epigenetic Stability in a ...
Tópico(s): Evolution and Genetic Dynamics
1925 - University of Chicago Press | The American Naturalist
... Bock Gu, Joo-Myung Ahn, Jung Shan Hwang, Takashi Gojobori, Michael Levin Long-range neural and gap junction ...
Tópico(s): Planarian Biology and Electrostimulation
1952 - University of Chicago Press | The Quarterly Review of Biology
... Ikuko Yuyama, Hiroshi Shimizu, Masafumi Nozawa, Kazuho Ikeo, Takashi Gojobori Different Endosymbiotic Interactions in Two Hydra Species Reflect ...
Tópico(s): Marine Toxins and Detection Methods
1963 - University of Chicago Press | Physiological Zoology
K Shimotohno, Yoshiko Takahashi, N. Shimizu, Takashi Gojobori, David W. Golde, I S Chen, Masanao Miwa, Takashi Sügimura,
The entire nucleotide sequence of an infectious clone of human T-cell leukemia virus type II provirus was determined. This provirus consists of 8952 nucleotides. In addition to long terminal repeats and gag, pol, env, and X, a protease gene that is responsible for processing the gag precursor protein was found. The protease gene is encoded in a different frame from gag and pol and was located between the gag and pol open reading frames. The 5' region of the protease gene overlaps the 3' gag region. ...
Tópico(s): Vector-Borne Animal Diseases
1985 - National Academy of Sciences | Proceedings of the National Academy of Sciences
R. C. Woodruff, Michael Ashburner,
... 10.1007/BF00498949 Hirotami T. Imai , Takeo Maruyama , Takashi Gojobori , Yutaka Inoue , and Ross H. Crozier Theoretical Bases ...
Tópico(s): Insect Resistance and Genetics
1978 - University of Chicago Press | The American Naturalist
Takashi Gojobori, Etsuko N. Moriyama, Yasuo Ina, Kazuho Ikeo, Tomoyuki Miura, Hajime Tsujimoto, Masanori Hayami, Shozo Yokoyama,
From what viruses the human immunodeficiency viruses (HIVs) originated is an extremely controversial question. To address this question, we have analyzed nucleotide sequences of simian immunodeficiency viruses (SIVs) and HIVs by using the techniques for understanding molecular evolution. In particular, we compared the nucleotide sequences of whole genomes, gene region by gene region, between a given pair of viruses, including four types of SIVs--isolated from mandrills (Papio sphinx), African green ...
Tópico(s): HIV/AIDS Research and Interventions
1990 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Takashi Gojobori, Etsuko N. Moriyama, Makoto Kimura,
Evolution of viral genes is characterized by enormously high speed compared with that of nuclear genes of eukaryotic organisms. In this paper, the evolutionary rates and patterns of base substitutions are examined for retroviral oncogenes, human immunodeficiency viruses (HIV), hepatitis B viruses (HBV), and influenza A viruses. Our results show that the evolutionary process of these viral genes can readily be explained by the neutral theory of molecular evolution. In particular, the neutral theory ...
Tópico(s): Protein Structure and Dynamics
1990 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Tomoyuki Miura, Jun-ichi Sakuragi, Meiko Kawamura, Masashi Fukasawa, Etsuko N. Moriyama, Takashi Gojobori, Koh-ichi Ishikawa, J. A. A. Mingle, Victor B.A. Nettey, Hirofumi Akari, Masayoshi Enami, Hajime Tsujimoto, Masanori Hayami,
We designed a universal primer (UNIPOL) for DNA amplification of AIDS-related viruses. The phylogenetic tree constructed from the presumed sequences amplified with UNIPOL was representative of the tree calculated from whole pol gene sequences so far reported. UNIPOL was able to amplify the sequences of all four major groups of primate lentiviruses and also that of a distinct virus from a Ghanaian patient with an AIDS-related complex, designated GH-2. This strain scarcely hybridizes with known HIV/ ...
Tópico(s): Herpesvirus Infections and Treatments
1990 - Lippincott Williams & Wilkins | AIDS
Toshihiko Shiroishi, Naoto Hanzawa, Tomoko Sagai, Masahiro Ishiura, Takashi Gojobori, Michael Steinmetz, Kazuo Moriwaki,
Tópico(s): Genetic Mapping and Diversity in Plants and Animals
1990 - Springer Science+Business Media | Immunogenetics
Takashi Gojobori, Etsuko N. Moriyama, Makoto Kimura,
This chapter describes methods for estimating total number of nucleotide substitutions. The initiation and termination codons are excluded from the comparison, because the former is usually invariant and changes of the latter are quite restrictive. When the number of differences varies depending on the types of base pairs, and furthermore when the value of K is expected to become more than 1.0, the four- and six-parameter methods are more suitable than other methods. In particular, the estimate ...
Tópico(s): Machine Learning in Bioinformatics
1990 - Academic Press | Methods in enzymology on CD-ROM/Methods in enzymology
Tópico(s): Vector-Borne Animal Diseases
1990 - Springer Science+Business Media | Journal of Molecular Evolution
Tatsuo Yamamoto, Takashi Gojobori, Takeshi Yokota,
Three families of the evolutionarily related pathogenic determinants in enterotoxigenic Escherichia coli and Vibrio cholerae O1, a family of cholera enterotoxin (CT) and heat-labile enterotoxin (LT) including CT, LTh, and LTp, a family of heat-stable enterotoxin I (STI) including STIa and STIb, and a family of K88 enteroadhesion fimbriae including K88ab, K88ac, and K88ad were analyzed for synonymous (silent) nucleotide substitutions by using the gene nucleotide sequences of earlier reports and the LTp ...
Tópico(s): Bacterial Genetics and Biotechnology
1987 - American Society for Microbiology | Journal of Bacteriology
Aota Shin-ichi, Takashi Gojobori, Katsuya Shigesada, Ozeki Haruo, Ikemura Toshimichi,
We determined the nucleotide (nt) sequences of cDNA and genomic clones for murine intracistemal type A particle (IAP) elements, which are retrovirus-like repetitive sequences in rodent genomes. The nucleotide sequence of the cDNA resembled that of retrovirus RNA genomes in its lack of the U5 sequence within the 3′ long terminal repeat. By sequence comparison of our clones with reported rodent IAP elements, we located the probable gag, pol and env gene regions. The sequences for the pal, env and the ...
Tópico(s): RNA modifications and cancer
1987 - Elsevier BV | Gene
Takashi Gojobori, Shozo Yokoyama,
Tópico(s): Bacteriophages and microbial interactions
1987 - Springer Science+Business Media | Journal of Molecular Evolution
Shozo Yokoyama, Takashi Gojobori,
Tópico(s): Vector-Borne Animal Diseases
1987 - Springer Science+Business Media | Journal of Molecular Evolution
Hideaki Bando, Jun Kusuda, Takashi Gojobori, Takeo Maruyama, S. Kawase,
The genome structure of a densovirus from a silkworm was determined by sequencing more than 85% of the complete genome DNA. This is the first report of the genome organization of an insect parvovirus deduced from the DNA sequence. In the viral genome, two large open reading frames designated 1 and 2 and one smaller open reading frame designated 3 were identified. The first two open reading frames shared the same strand, while the third was found in the complementary sequence. Computer analysis suggested ...
Tópico(s): Animal Virus Infections Studies
1987 - American Society for Microbiology | Journal of Virology
Satoshi Horai, Takashi Gojobori, Ei Matsunaga,
Tópico(s): Metabolomics and Mass Spectrometry Studies
1987 - Springer Science+Business Media | Human Genetics
The relative contributions of germline gene variation and somatic mutation to immunoglobulin diversity were studied by comparing germline gene sequences with their rearranged counterparts for the mouse VH, V kappa, and V lambda genes. The mutation rate at the amino acid level was estimated to be 7.0% in the first and second complementarity-determining regions (CDRs) and 2.0% in the framework regions (FRs). The difference in the mutation rate at the nucleotide level between the CDRs and FRs was of ...
Tópico(s): Blood groups and transfusion
1986 - Oxford University Press | Molecular Biology and Evolution
Satoshi Horai, Takashi Gojobori, Ei Matsunaga,
Analysis of the data for mitochondrial DNA using restriction enzymes revealed a total of 117 different types among Japanese, Caucasians and Negroes. The average number of nucleotide substitutions for the Japanese was almost the same as that for the Caucasians, whereas the value for the Negroes was almost two times larger than those for the other two races. A phylogenetic tree constructed by genetic distances showed distinct clusters of individuals from the same racial group, although there were ...
Tópico(s): Metabolism and Genetic Disorders
1986 - Genetics Society of Japan | The Japanese Journal of Genetics
Hirotami T. Imai, Takeo Maruyama, Takashi Gojobori, Yutaka Inoue, Ross H. Crozier,
Data from the literature (tables 1, 2; fig. 1) show that the relative probabilities of occurrence for the various categories of spontaneous chromosomal mutations do not match those predicted by both the random-contact-and-exchange model (basically equivalent to the exchange theory of Revell) and the random-breakage-and-reunion model (i.e., the breakage-and-reunion theory of Sax or of Muller). These models do not take into account recent findings that, during the meiotic prophase and especially at pachytene, ...
Tópico(s): Plant Genetic and Mutation Studies
1986 - University of Chicago Press | The American Naturalist
Etsuro Orito, M. Mizokami, Y Ina, Etsuko N. Moriyama, Nobutoshi Kameshima, Masakazu Yamamoto, Takashi Gojobori,
An analysis of molecular phylogeny was undertaken to examine whether the evolution of the hepadnavirus family is host-dependent. Using the nucleotide sequences of 18 strains, we constructed phylogenetic trees. The trees obtained show that all 12 strains of hepatitis B virus can be classified into four subgroups that are not compatible with conventional subtypes. We estimated the rate of synonymous (silent) substitution for hepatitis B virus to be 4.57 x 10(-5) per site per year. Applying this rate ...
Tópico(s): Animal Virus Infections Studies
1989 - National Academy of Sciences | Proceedings of the National Academy of Sciences
Hajime Tsujimoto, Akira Hasegawa, Noboru Maki, Masashi Fukasawa, Tomoyuki Miura, Stephan Speidel, Robert W. Cooper, Etsuko N. Moriyama, Takashi Gojobori, Masanori Hayami,
Tópico(s): Cytomegalovirus and herpesvirus research
1989 - Nature Portfolio | Nature
Shozo Yokoyama, Linda H. Chung, Takashi Gojobori,
A phylogenetic tree for different human immunodeficiency viruses type 1 (HIV1) and type 2 (HIV2), lentiviruses, and oncoviruses has been constructed by comparing the nucleotide sequences of the two regions of their pol genes that encode the reverse transcriptase and endonuclease/integrase. The analysis indicates that (1) different HIV1 strains form one cluster and their common ancestor diverged from the ancestor of HIV2, (2) the common ancestor of the HIV1 and HIV2 strains diverged from that of the ...
Tópico(s): Animal Disease Management and Epidemiology
1988 - Oxford University Press | Molecular Biology and Evolution
Kiyoshi Hayasaka, Takashi Gojobori, S Horai,
We determined nucleotide sequences of homologous 0.9-kb fragments of mitochondrial DNAs (mtDNAs) derived from four species of old-world monkeys, one species of new-world monkeys, and two species of prosimians. With these nucleotide sequences and homologous sequences for five species of hominoids, we constructed a phylogenetic tree for the four groups of primates. The phylogeny obtained is generally consistent with evolutionary trees constructed in previous studies. Our results also suggest that the ...
Tópico(s): Machine Learning in Bioinformatics
1988 - Oxford University Press | Molecular Biology and Evolution