Limpar
706 resultados

Acesso aberto

Tipo do recurso

Ano de criação

Produção nacional

Revisado por pares

Áreas

Idioma

Editores

Jornais Acesso aberto

By Donald Macintyre, Labour Correspondent, From Paul Ellman, By Annabel Ferriman, By John Whitmore, By Tony Samstag, By Lucy Hodges, By Anthony Bevins Political Correspondent, From Clifford Webb, By Our Labour Editor, By Peter Evans, By Frances Gibb, By George Clark, By David Felton Labour Reporter, By a Staff Reporter, By Anthony Bevins, Political Correspondent, By Paul Routledge, Labour Editor, By Hugh Noyes, Parliamentary Correspondent, By Richard Evans, From Richard Ford, From Ronald Kershaw, From John Chartres, By Annabel Ferriman Health Services Correspondent, From Richard Wigg, From Charles Hargrove, From Peter Nichols, From Christopher Thomas, From Patrick Knight, From Our Own Correspondent, From Kuldip Nayar, From Our Correspondent, From David Watts, From David Bonavia Peking, From Christopher Walker, From Roger Boyes, From Michael Hamlyn, From Peter Watson, From Michael Hornsby, From an Murray, By Caroline Moorehead, by Suzy Menkes, PHS, SIMON GOURLAY, D. STUART-SMITH., CHRISTOPHER BLAND, T. M. McGOLDRICK, L. A. MORITZ, NICHOLAS KALDOR, MICHAEL CROFT, D. BRYCE-SMITH, JILL TWEEDIE, DORA NASH, MICHAEL TRACEY, SHIRLEY WILLIAMS, A. R. FERSHT, PATRICK McGRATH, ELIZABETH OLIVER, ROBIN A. HOWARD, R. E. MEGARRY, By Bryan Appleyard, By Harry Golombek, Chess Correspondent, Professor William A. Armstrong writes:, Bryan Appleyard, John Percival, John Russell Taylor, Paul Griffiths, Barry Millington, By Melvyn Westlake, By Margareta Pagano, By Frances Williams, By Torin Douglas, By Michael Baily, By Peter Hill, Industrial Editor, By Jonathan Davis, Energy Correspondent, By Our Industrial Editor, John Whitmore, Peter Wainwright, From Bailey Morris, By Peter West, Rugby Correspondent, From Richard Streeton, from John Ballantine, By John Hennessy, By Stuart Jones, Football Correspondent, By Srikumar Sen, Boxing Correspondent, By Jim Railton, By Rex Bellamy, By Robert Pryce, By Nicholas Harling, By Paul Harrison, By Michael Seely, By Ian Reid, Edited by Peter Dear, By David Nicholson-Lord,

... Author of definitive work on Shakespeare's sources, Takashi Shimura, Mr Norman Tetlow, Prof Witold Trampczynski, Professor Gershom ...

1982 - Gale Group | TDA

Carta Acesso aberto Revisado por pares

М.D. Тronko, Vladimir Saenko, Victor Shpak, Bogdanova Ti, Shinichi Suzuki, Shunichi Yamashita,

... Suzuki, Satoru Suzuki, Toshihiko Fukushima, Sanae Midorikawa, Hiroki Shimura, Takashi Matsuzuka, Tetsuo Ishikawa, Hideto Takahashi, Akira Ohtsuru, Akira ...

Tópico(s): Radioactive contamination and transfer

2014 - Mary Ann Liebert, Inc. | Thyroid

Revisão Revisado por pares

Takaya Shimura, Takashi Joh,

Acute malignant colorectal obstruction (AMCO) is an emergency associated with colorectal cancer (CRC). Emergency surgery is standard therapy for AMCO, and 1-stage surgery without colostomy is preferable, but it is occasionally difficult in the emergency setting. A self-expandable metallic stent (SEMS) enables noninvasive colonic decompression and subsequent 1-stage surgery, which has been widely applied for CRC with AMCO. However, recent accumulation of high-quality evidence has highlighted some problems ...

Tópico(s): Colorectal and Anal Carcinomas

2016 - Lippincott Williams & Wilkins | Journal of Clinical Gastroenterology

Revisão Acesso aberto Revisado por pares

Shunichi Yamashita, Hitoshi Ohto, Masafumi Abe, Koichi Tanigawa, Shunichi Yamashita, Kenji Kamiya, Seiji Yasumura, Mitsuaki Hosoya, Shinichi Suzuki, Akira Ohtsuru, Akira Sakai, H. Yabe, Masaharu Maeda, Keisei Fujimori, Tetsuo Ishikawa, Tetsuya Ohira, Tsuyoshi Watanabe, Hiroaki Satoh, Satoru Suzuki, Toshihiko Fukushima, Sanae Midorikawa, Hiromi Shimura, Takashi Matsuzuka, Hirofumi Mashiko, Aya Goto, Kenneth E. Nollet, Hideto Takahashi, Yoshisada Shibata, Makoto Miyazaki, Shiro Matsui, Seisho Tanaka,

Five years have passed since the Great East Japan Earthquake and the subsequent Fukushima Daiichi Nuclear Power Plant accident on 11 March 2011. Countermeasures aimed at human protection during the emergency period, including evacuation, sheltering and control of the food chain were implemented in a timely manner by the Japanese Government. However, there is an apparent need for improvement, especially in the areas of nuclear safety and protection, and also in the management of radiation health ...

Tópico(s): Radioactivity and Radon Measurements

2016 - Elsevier BV | Clinical Oncology

Artigo Revisado por pares

Shinichi Suzuki, Satoru Suzuki, Toshihiko Fukushima, Sanae Midorikawa, Hiroki Shimura, Takashi Matsuzuka, Tetsuo Ishikawa, Hideto Takahashi, Akira Ohtsuru, Akira Sakai, Mitsuaki Hosoya, Seiji Yasumura, Kenneth E. Nollet, Tetsuya Ohira, Hitoshi Ohto, Masafumi Abe, Kenji Kamiya, Shunichi Yamashita,

Thyroid nodules and cancers are rare in children compared with adults. However, after the 1986 Chernobyl Nuclear Power Plant accident, a rapid increase in childhood thyroid cancer was observed. To avoid any confusion and misunderstanding of data obtained in Fukushima after the 2011 nuclear accident, baseline prevalence of thyroid nodules and cancers should be carefully assessed with standardized criteria systematically, and comprehensively applied to the population perceived to be at risk.Under ...

Tópico(s): Radiation Dose and Imaging

2016 - Mary Ann Liebert, Inc. | Thyroid

Artigo Revisado por pares

Yoshihiro Hishikawa, Haruya Shimura, Takashi UEDA, Ayumi Sasaki, Yuki Ishii,

Experimental procedure for precisely characterizing the performance of perovskite solar cells such as the current-voltage (I-V) curves and the maximum output power Pmax is investigated, based on results of the samples with different structures. Special care is taken for the hysteresis effects. Confirming the hysteresis of the I-V curves in a wide range including the timescale of minutes is preferred for precise measurements, since the hysteresis remains for more than 10 min in some samples. When ...

Tópico(s): Conducting polymers and applications

2016 - Elsevier BV | Current Applied Physics

Artigo Revisado por pares

Keima Abe, Shigenori Kido, Tomoo Maeda, Daisuke Kami, Hideyuki Matsuura, Hanako Shimura, Takashi Suzuki,

Abstract Most Brassicaceae plants produce glucosinolates (GSLs), which are hydrolyzed to form isothiocyanates (ITCs) that contribute to a stimulative flavor and antibiotic activity beneficial to human health. Three glucosinolates (GSLs), gluconapin, glucoibarin and glucobrassicin, were isolated from plants of Cardamine fauriei Maxim. (Brassicaceae; Ezo-wasabi in Japanese), a wild, edible herb originating from Hokkaido, Japan. These GSLs comprise two types: aliphatic (gluconapin and glucoibarin) and indolic ( ...

Tópico(s): Plant Stress Responses and Tolerance

2015 - Elsevier BV | Scientia Horticulturae

Artigo Revisado por pares

Yasunobu Yasoshima, Tsuyoshi Shimura, Takashi Yamamoto,

Amygdalar neuronal responses to sodium saccharin used as the conditioned stimulus (CS) and to other taste stimuli including sucrose, NaCl, HCl and quinine hydrochloride were recorded before and after the acquisition of conditioned taste aversion (CTA) in freely behaving rats. Of 73 units recorded from the basolateral nucleus of the amygdala (BLA), 17 (23%) and 1 (1%) exhibited facilitatory and inhibitory responses, respectively, to both the CS and sucrose after aversive conditioning to the CS. On the ...

Tópico(s): Neuroscience and Neuropharmacology Research

1995 - Lippincott Williams & Wilkins | Neuroreport

Artigo Acesso aberto Revisado por pares

Masashi Seto, Kazuhide Kimbara, Minoru Shimura, Takashi Hatta, Masao Fukuda, Kazuyoshi Yano,

We have characterized a biphenyl degrader, Rhodococcus sp. strain RHA1. Biphenyl-grown cells of strain RHA1 efficiently transformed 45 components in the 62 major peaks of a polychlorinated biphenyl (PCB) mixture of Kanechlors 200, 300, 400, and 500 within 3 days, which includes mono- to octachlorobiphenyls. Among the intermediate metabolites of PCB transformation, di- and trichlorobenzoic acids were identified. The gradual decrease of these chlorobenzoic acids during incubation indicated that these ...

Tópico(s): Chemical Reactions and Isotopes

1995 - American Society for Microbiology | Applied and Environmental Microbiology

Artigo Revisado por pares

Tsuyoshi Shimura, Takashi Yamamoto, Minoru Shimokochi,

A total of 74 single unit activities was recorded from the medial preoptic-anterior hypothalamic continuum (MPOA) during free copulatory behavior of male rats. Forty-six units (62.2%) showed changed activities during at least one phase of male copulatory movements; 26 units (35.1%) increased in the firing rate during pelvic thrusting; 32 units (43.2%) increased in activity during backward jumping immediately after intromission; only one unit (1.4%) showed decreased firing rate during thrusting and backward ...

Tópico(s): Stress Responses and Cortisol

1994 - Elsevier BV | Brain Research

Artigo Acesso aberto Revisado por pares

Yoshihiro Takamura, Masahiko Shimura, Takashi Katome, Hideaki Someya, Masahiko Sugimoto, Takao Hirano, Taiji Sakamoto, Makoto Gozawa, Takehiro Matsumura, Masaru Inatani,

Background/Aims To investigate whether intravitreal injection of triamcinolone acetonide (IVTA) combined with vitrectomy prevents postoperative inflammation in patients with vitreous haemorrhage (VH) due to proliferative diabetic retinopathy (PDR). Methods This prospective, multicentre, randomised study conducted at seven sites in Japan enrolled patients diagnosed as having VH following PDR. Patients underwent vitrectomy with (IVTA+VIT group) or without (VIT group) IVTA at the end of the surgery. Anterior ...

Tópico(s): Vascular Malformations Diagnosis and Treatment

2018 - BMJ | British Journal of Ophthalmology

Artigo Acesso aberto Revisado por pares

Akira Ohtsuru, Sanae Midorikawa, Tetsuya Ohira, Satoru Suzuki, Hideto Takahashi, Michio Murakami, Hiroki Shimura, Takashi Matsuzuka, Seiji Yasumura, Shinichi Suzuki, Susumu Yokoya, Yuko Hashimoto, Akira Sakai, Hitoshi Ohto, Shunichi Yamashita, Koichi Tanigawa, Kenji Kamiya,

Ultrasonographic (US) screening for thyroid cancer was performed in the Fukushima Health Management Survey after the 2011 Fukushima Daiichi nuclear power station accident. Clinical characteristics of thyroid cancers screened by US among children and young adults during the first 5 years after the accident were analyzed.To evaluate the number of detected thyroid cancers by age group within 5 years of the Fukushima Daiichi nuclear power station accident and to compare the basic clinical characteristics ...

Tópico(s): Radioactivity and Radon Measurements

2018 - American Medical Association | JAMA Otolaryngology–Head & Neck Surgery

Artigo Revisado por pares

Makoto Matsubayashi, Takeshi Hatta, Takeharu Miyoshi, A Anisuzzaman, Kazumi Sasai, Kameo SHIMURA, Takashi Isobe, Kiyoshi Kita, Naotoshi Tsuji,

Seven species of Eimeria are responsible for coccidiosis in chickens. Eimeria tenella is one of the most pathogenic parasites since it is associated with high mortality and great economic impact. The life cycle of the parasite includes development in the environment and in the intestinal tract. We conducted RNA sequencing using a next generation sequencer to obtain transcriptome information from the sporulating oocysts, and sporozoites. We collected 2.8 million 75 bp reads of a short-tag sequence, ...

Tópico(s): Helminth infection and control

2013 - Elsevier BV | Infection Genetics and Evolution

Artigo Revisado por pares

Yoshikazu Hirata, Hiromi Kataoka, Takaya Shimura, Takashi Mizushima, Tsutomu Mizoshita, Satoshi Tanida, Toshio Kamiya, Takashi Joh,

Objective. Aspirin-induced enteropathy is increasing, but whether the type of aspirin affects the gastrointestinal (GI) bleeding, especially small intestine, is unclear. The incidence of GI bleeding for buffered aspirin and enteric-coated aspirin was evaluated in patients receiving long-term low-dose aspirin (LDA) for cardiovascular (CV) diseases. Methods. This retrospective cohort study assessed overt GI bleeding, decreased hemoglobin levels suspecting small bowel blood loss, and CV death in patients ...

Tópico(s): Platelet Disorders and Treatments

2011 - Taylor & Francis | Scandinavian Journal of Gastroenterology

Artigo Revisado por pares

Masayasu Shimura, Takashi UEDA, Gyungmin Choi, Mamoru Tanahashi, Toshio Miyauchi,

Simultaneous dual-plane CH planar laser induced fluorescence (PLIF), single-plane OH PLIF and dual-plane stereoscopic particle image velocimetry (PIV) measurement has been developed to investigate three-dimensional structures of methane-air turbulent premixed flame. Dual-plane CH PLIF system consists of two independent conventional CH PLIF measurement systems and laser beams from each laser system are led to parallel optical pass using the difference of polarization, and CH PLIF is conducted in two ...

Tópico(s): Atmospheric and Environmental Gas Dynamics

2010 - Elsevier BV | Proceedings of the Combustion Institute

Artigo Acesso aberto Revisado por pares

Dong Hun Kim, Kazunori Shimura, Takashi Horiguchi,

The effect of loading on chloride penetration into concrete is evaluated in this study. It is found that the chloride penetration rates for OPC concrete and blast furnace slag BFS concrete under the tensile stress were increased by 29% and 77%, respectively. The diffusion coefficient of BFS concrete was lower than that of conventional concrete without BFS, no loads and stress states. Under tensile stress, the diffusion coefficient for BFS and plain concrete showed higher values with increasing stress. ...

Tópico(s): Innovative concrete reinforcement materials

2010 - | Journal of Advanced Concrete Technology

Artigo Revisado por pares

Tadashi Inui, Tsuyoshi Shimura, Takashi Yamamoto,

When subjects receive a taste stimulus (conditioned stimulus, CS) that is paired with malaise, they acquire conditioned taste aversion (CTA). It is thought that the taste CS changes from appetitive to aversive after acquisition of CTA. Previous studies have suggested that the ventral pallidum (VP) is involved in the hedonics of taste stimuli, therefore the present study investigated whether the VP is a neural substrate for the shift in preference of the CS after CTA acquisition. In the first experiment, ...

Tópico(s): Neurotransmitter Receptor Influence on Behavior

2007 - Elsevier BV | Brain Research

Artigo Revisado por pares

Tadashi Inui, Tsuyoshi Shimura, Takashi Yamamoto,

Rats failed to acquire aversions to odor stimulus, which was followed 30 min later by an unconditioned stimulus (US). However, when the odor stimulus was accompanied by a taste stimulus, they acquired odor aversions as well as taste aversions. In this phenomenon, referred to as a taste-potentiated odor aversion, lesions of the amygdala disrupted both taste and odor aversions, whereas lesions of the parvicellular part of ventroposteromedial thalamic nucleus (VPMpc) or insular cortex (IC) disrupted taste ...

Tópico(s): Circadian rhythm and melatonin

2006 - American Psychological Association | Behavioral Neuroscience

Artigo Acesso aberto Revisado por pares

Michiyo Matsumoto, M. Tsuji, J. Okuda, Hidekazu Sasaki, Kazuhiko Nakano, Kenji Osawa, Susumu Shimura, Takashi Ooshima,

Cacao bean husk extract (CBH) has been shown to possess antibacterial and antiglucosyltransferase activities through its unsaturated fatty acids and epicatechin polymers, respectively. In the present study, the antiplaque activities of CBH were examined in vitro and in vivo . The extract inhibited the adherence of Streptococcus mutans MT8148 to saliva‐coated hydroxyapatite and reduced the accumulation of artificial dental plaque by S. mutans MT8148 on orthodontic wire. The number of mutans streptococci ...

Tópico(s): HIV/AIDS oral health manifestations

2004 - Wiley | European Journal Of Oral Sciences

Artigo Acesso aberto Revisado por pares

Daisuke Miyazawa, Gouri Mukerjee-Dhar, Minoru Shimura, Takashi Hatta, Kazuhide Kimbara,

A 10 kb DNA fragment was isolated using a DNA probe derived from the N-terminal amino acid sequence of the extradiol dioxygenase purified from naphthalene-grown Bacillus sp. JF8, a thermophilic naphthalene and polychlorinated biphenyl degrader. The cloned DNA fragment had six open reading frames, designated nahHLOMmocBnahC based on sequence homology, of which the products NahH_JF8 and NahC_JF8 were extradiol dioxygenases. Although NahC_JF8 and NahH_JF8 exhibit low homology to known extradiol dioxygenases, ...

Tópico(s): Pesticide and Herbicide Environmental Studies

2004 - Microbiology Society | Microbiology

Artigo Revisado por pares

Kenichi Tokita, Zoltán Karádi, Tsuyoshi Shimura, Takashi Yamamoto,

Our previous studies have demonstrated that gustatory neurons in the parabrachial nucleus (PBN) show altered responses after the acquisition of conditioned taste aversion (CTA) to NaCl. The present study was conducted 1) to examine centrifugal influences on the altered gustatory activity of CTA-trained rats, and 2) to evaluate the role of amiloride-sensitive (ASN) and -insensitive NaCl (AIN) best units in coding the taste of NaCl. Animals were separated into 2 groups: a CTA group that had acquired taste ...

Tópico(s): Neuroscience and Neuropharmacology Research

2004 - American Physiological Society | Journal of Neurophysiology

Artigo Revisado por pares

Shoko Taniguchi, Yoko Imayoshi, Eri Kobayashi, Yoshie Takamatsu, Hideyuki Ito, Tsutomu Hatano, Hiroshi Sakagami, Harukuni Tokuda, Hoyoku Nishino, Daigo Sugita, Susumu Shimura, Takashi Yoshida,

Callus tissue cultures induced from an axenic leaf of Eriobotrya japonica (Rosaceae) produced triterpenes in large amounts (ca. 50 mg/g dry wt). Nine triterpenes were characterized as ursolic acid, oleanolic acid, 2alpha-hydoxyursolic acid, maslinic acid, tormentic acid, 2alpha, 19alpha-dihydroxy-3-oxo-urs-12-en-28-oic acid, hyptadienic acid and a mixture of 3-O-cis-p-coumaroyltormentic acid and 3-O-trans-p-coumaroyltormentic acid. The triterpene composition in the callus tissues was noticeably different ...

Tópico(s): Toxin Mechanisms and Immunotoxins

2002 - Elsevier BV | Phytochemistry

Artigo Revisado por pares

Akashi Ohtaki, Shin Kondo, Yoichiro Shimura, Takashi Tonozuka, Yoshiyuki Sakano, S. Kamitori,

Phe286 located in the center of the active site of α-amylase 2 from Thermoactinomyces vulgaris R-47 (TVAII) plays an important role in the substrate recognition for cyclomaltooligosaccharides (cyclodextrins). The X-ray structures of mutant TVAIIs with the replacement of Phe286 by Ala (F286A) and Tyr (F286Y) were determined at 3.2 Å resolution. Their structures have no significant differences from that of the wild-type enzyme. The kinetic analyses of Phe286-replaced variants showed that the variants ...

Tópico(s): Enzyme Catalysis and Immobilization

2001 - Elsevier BV | Carbohydrate Research

Artigo

Yukiko Andoh, Sanae Shimura, Takashi Sawai, Hidetada Sasaki, Tamotsu Takishima, Kunio Shirato,

Sjögren's syndrome is characterized by a decrease in exocrine gland secretion and the destruction of secretory tissue and cells, that is, salivary and lacrimal glands. Although patients with Sjögren's syndrome have chronic cough and sometimes sputum, we have little knowledge concerning the morphology of their airways. We performed morphometric analysis of goblet cells and bronchial glands and compared them with intraluminal mucus volume by measuring the mucus-occupying ratio (MOR) in the airways ...

Tópico(s): Voice and Speech Disorders

1993 - American Thoracic Society | American Review of Respiratory Disease

Revisão Revisado por pares

Leonard D. Kohn, Shinji Kosugi, Toshiaki Ban, Motoyasu Saji, Shoichiro Ikuyama, Cesidio Giuliani, Akinari Hidaka, Hiroki Shimura, Takashi Akamizu, Kazuo Tahara, John Moriarty, Bellur S. Prabhakar, Dinah S. Singer,

Key Words: major histocompatibility complexgonadotropin receptorthyroid stimulating antibodiesthyroid blocking antibodiesGraves' diseasemyxedema

Tópico(s): Thyroid Disorders and Treatments

1992 - Taylor & Francis | International Reviews of Immunology

Artigo Revisado por pares

Yukiko Andoh, Sanae Shimura, Takashi Aikawa, Hidetada Sasaki, Tamotsu Takishima,

We performed a morphometric analysis of peribronchiolar and perivascular fibrosis in lungs obtained at autopsy from six patients with chronic bronchitis, six with pulmonary emphysema, and four normal control subjects. The areas of fibrosis outside the smooth muscle layer of bronchioles and outside the external elastic lamina of muscular pulmonary arteries were measured and their thickness was then calculated by assuming a round airway or artery. Patients with chronic bronchitis had significantly ...

Tópico(s): Congenital Diaphragmatic Hernia Studies

1992 - Elsevier BV | CHEST Journal

Artigo Acesso aberto Revisado por pares

S Ikuyama, Hans Helmut Niller, Hiroki Shimura, Takashi Akamizu, Leonard D. Kohn,

Genomic clones containing 1.7 kilobases of the 5'-flanking region of the rat TSH receptor (TSHR) plus coding sequence from the ATG initiation codon [1 basepair (bp)] to the start of the first intron (170 bp) have been isolated and characterized. RNAase protection, primer extension, and cDNA sequences cloned by the anchored polymerase chain reaction identified multiple transcriptional start sites, the major ones clustered between -89 to -68 bp. This portion of the 5'-flanking region has neither a TATA ...

Tópico(s): Immune Response and Inflammation

1992 - Oxford University Press | Molecular Endocrinology

Artigo Revisado por pares

Thomas R. Scott, Richard S. Perrotto,

... Parabrachial Neuronal ActivitiesKen'ichi Tokita, Zoltán Karádi, Tsuyoshi Shimura, and Takashi Yamamoto1 July 2004 | Journal of Neurophysiology, Vol. 92, ...

Tópico(s): Olfactory and Sensory Function Studies

1980 - American Physiological Society | Journal of Neurophysiology