... jinken hakubutsukan 20-nen no ayumi to sōgō tenji no gaiyō [The 20-year trajectory of the ... 2008. Takeshi Asaji, ‘Sabetsu jinken to kin-gendai tenji no shatei’ [A range of issues on discrimination, ... 2008. Osaka Human Rights Museum, Osaka jinken hakubutsukan tenji sōgō zuroku: Jinken kara mita Nihon shakai [The ... Osaka Human Rights Museum, Osaka jinken hakubutsukan sogo tenji zuroku: Watashi ga mukiau Nihon shakai no sabetsu ... 13–14. Keiko Nakama, ‘Sabetsu mondai to hakubutsukan tenji’ [The problem of discrimination and museum exhibitions], Osaka ...
Tópico(s): Educator Training and Historical Pedagogy
2010 - Routledge | The International Journal of Human Rights
... by Prince Naka no Oe 43t5i (later Emperor Tenji ~it) in 645. As has been observed, however, ... proved impossible, however, to implement these fully before Tenji's death in late 671. Shortly afterward, a ...
Tópico(s): Chinese history and philosophy
1986 - Sophia University | Monumenta Nipponica
Stefana Đukanović, Tea Ganić, Branka Lončarević, Stefana Cvetković, Biljana Nikolić, Dina Tenji, Danijela Randjelović, Dragana Mitić-Ćulafić,
Because the Staphylococcus aureus is one of the most well-known pathogens associated with medical devices and nosocomial infections, the aim of the study was to examine antibiofilm potential of emodin against it.Antibacterial activity was examined through microdilution assay. Antibiofilm testing included crystal violet staining of biofilm biomass and morphology analysis by Atomic force microscopy (AFM). Furthermore, aerobic respiration was monitored using the Micro-Oxymax respirometer. For investigation ...
Tópico(s): Mycobacterium research and diagnosis
2021 - Oxford University Press | Journal of Applied Microbiology
Kesavan Selvam, K.A. Martin Xavier, Avadootha Shivakrishna, Tenji Pem Bhutia, Satish Kamat, Latha Shenoy,
The pollution due to marine debris is a serious environmental threat in many parts of the world. The abundance of marine debris, composition and its distribution over the seafloor along north-east coast of Arabian coast was studied through trawl based swept method. Experimental fishing was conducted fortnightly using shrimp bottom trawl and collected debris was categorized as per standard protocols. A total of 1077 pieces of debris (11.7 kg dry weight) were collected from 25 hauls. The average number ...
Tópico(s): Recycling and Waste Management Techniques
2020 - Elsevier BV | The Science of The Total Environment
Dina Tenji, Bojana Micić, Sándor Sipos, Branko Miljanović, Ivana Teodorović, Sonja Kaišarević,
Abstract Background A prerequisite for long-term survival of populations under multi-stress conditions is their capacity to set up efficient adaptive strategies. However, changes in the activity of molecular biomarkers have been for decades considered as early signals of the deterioration of the fish health and evidence of stress-related adverse biological effects. The aim of this study was to show that such changes actually represent adaptive response of fish to chemical stress. Gene expression ...
Tópico(s): Aquaculture Nutrition and Growth
2020 - Springer Science+Business Media | Environmental Sciences Europe
Purpose The purpose of this paper is to apply an existing theoretical model of organisational culture contextualised for total quality management (TQM) as a means of assessing the readiness for implementing TQM in the workplace. The “Amalgamated Model” is a hybrid that encapsulates organisational culture traits and their relative contribution as indictors of effective TQM implementation. Design/methodology/approach A questionnaire that would test the theoretical model was devised and administered ...
Tópico(s): Organizational Leadership and Management Strategies
2019 - Emerald Publishing Limited | The TQM Journal
Akira Nagasaki, Saku Kijima, Tenji Yumoto, Miku Imaizumi, Ayana Yamagishi, Hyonchol Kim, Chikashi Nakamura, Taro Q.P. Uyeda,
Actin, a major component of microfilaments, is involved in various eukaryotic cellular functions. Over the past two decades, actin fused with fluorescent protein has been used as a probe to detect the organization and dynamics of the actin cytoskeleton in living eukaryotic cells. It is generally assumed that the expression of fusion protein of fluorescent protein does not disturb the distribution of endogenous actin throughout the cell, and that the distribution of the fusion protein reflects that ...
Tópico(s): Cell Image Analysis Techniques
2017 - Japan Society of Cell Biology | Cell Structure and Function
Yuko Ogawa, Yuuko Fujii, Reina Sugiyama, Tenji Konishi,
Yokukansan is a traditional Japanese "Kampo" medicine derived from Yi-Gan San in traditional Chinese medicine. Many studies have been published on its effects and mechanisms. In this study, we focused on the sleep-promoting effects of Yokukansan.Yokukansan composes of seven crude drugs: Uncaria Hook, Bupleurm Root, Cnidium Rhizome, Japanese Angelica Root, Poria Sclerotium, Atractylodes Lancea Rhizome, and Glycyrrhiza. Although each has distinctive effects in isolation, they combine to work as a sleep ...
Tópico(s): Pharmacological Effects of Natural Compounds
2015 - Elsevier BV | Journal of Ethnopharmacology
... Available: http://www.nimd.go.jp/archives/english/tenji/e_corner/qa1/q5.html [accessed 27 August ...
Tópico(s): Toxic Organic Pollutants Impact
2013 - National Institute of Environmental Health Sciences | Environmental Health Perspectives
As part of our search for sedative substances from natural sources, we isolated two novel amino acid amides connected with the fructopyranose, kwansonine A (1) and kwansonine B (2), together with three known amino acid amides, longitubanine A (3), longitubanine B (4), and pinnatanine (5), from Hemerocallis fulva L. var. sempervirens (ARAKI) M. HOTTA. The structures of 1 and 2 have been determined on the spectroscopic evidences as N2-(1-β-D-fructopyranosyl)-N5-(2′,5′-dihydro-2′-furyl-3′-hydroxymethyl)- ...
Tópico(s): Agricultural Productivity and Crop Improvement
2009 - Pharmaceutical Society of Japan | Chemical and Pharmaceutical Bulletin
Tenji Konishi, Shigeo Kondô, Nahoko Uchiyama,
The larvicidal activities of three sesquiterpenes, alantolactone, isoalantolactone and dihydroisoalantolactone, isolated from the roots of Inula helenium (Compositae) against 3rd and 4th instars of Aedes albopictus (Diptera: Culicidae) and Paratanytarsus grimmii (Diptera: Chironomidae), were examined. The two sesquiterpenes, alantolactone and isoalantolactone, showed LC50 values of 2.7 μg/ml and 11.9 μg/ml for A. albopictus, and 5.1 μg/ml and 4.1 μg/ml for P. grimmii within 48 h, respectively. Alantolactone ...
Tópico(s): Essential Oils and Antimicrobial Activity
2008 - Springer Science+Business Media | Applied Entomology and Zoology
... leaving Osaka, I visited my former mentor, Professor Tenji Taniguchi, to tell him of my plans. He ...
Tópico(s): Neuroscience of respiration and sleep
2008 - Elsevier BV | Journal of Biological Chemistry
Nahoko Uchiyama, Ik Hwi Kim, Ruri Kikura‐Hanajiri, Nobuo Kawahara, Tenji Konishi, Yukihiro Goda,
Flavanone glycosides, such as naringin and neohesperidin, are distributed in some Citrus species and have a chiral center in the C-2 position of the flavanone moiety. Naringin and neohesperidin (2S-form) were separated from the corresponding C-2 epimers (2R-epi-form) by normal-phase HPLC using a polysaccaride-derived chiral stationary phases (CSPs), CHIRALPAK® IB. The analyses of commercial samples of naringin revealed that the relative ratios of naringin to the C-2 epimer were 29–89%. In the case ...
Tópico(s): Bioactive natural compounds
2007 - Elsevier BV | Journal of Pharmaceutical and Biomedical Analysis
Tenji Konishi, Takao Konoshima, Akihiro Daikonya, Susumu Kitanaka,
From a MeOH extract of the aerial part of Piper futokadsura, the tetrahydrofuran lignans, futokadsurin A [(7S,8S,7′S,8′R)-3,4,3′-trimethoxy-4′-hydroxy-7,7′-epoxylignan], futokadsurin B [(7R,8R,7′R,8′S)-3,4-dimethoxy-3′,4′-methylenedioxy-7,7′-epoxylignan], and futokadsurin C [(7R,8R,7′S,8′S)-3,4-methylenedioxy-3′,4′-dimethoxy-7,7′-epoxylignan] were isolated, together with nine known neolignans. In addition, L-tryptophan, pellitorine, phytol, elemicin, and 1,2,4-trimethoxyphenyl-5-aldehyde were isolated. ...
Tópico(s): Traditional and Medicinal Uses of Annonaceae
2005 - Pharmaceutical Society of Japan | Chemical and Pharmaceutical Bulletin
Tenji Konishi, Kiyonori Yamazoe, Takao Konoshima, Yasuhiro Fujiwara,
Labdane-type diterpenes, called excoecarins S, T1, and T2 were isolated from the resinous wood of Excoecaria agallocha, along with three known compounds, ent-12-oxo-2,3-secobeyer-15-ene-2,3-dioic acid, agallochin H, and ent-15-epoxy-beyerane-3α-ol. Their structures were elucidated on the basis of spectroscopic data, chemical evidence, and X-ray analysis.
Tópico(s): Biological Activity of Diterpenoids and Biflavonoids
2003 - Elsevier BV | Phytochemistry
Tenji Konishi, Kiyonori Yamazoe, Masahiro Kanzato, Takao Konoshima, Yasuhiro Fujiwara,
Three new diterpenoids, excoecarins V1-V3 (1-3) and a new flavanone glycoside (7) were isolated from the fresh stem of Excoecaria agallocha L. Their structures were elucidated as: 2alpha,3alpha,18-trihydroxy-3beta,20-epoxybeyer-15-ene (1), ent-2,3-secokaur-16-en-2,3-dioic acid (2), ent-3,4-seco-16alpha-hydroxyatis-4(19)-en-3-oic acid (3), and 3,5,7,3',5'-pentahydroxy-2R,3R-flavanonol 3-O-alpha-L-rhamnopyranoside (7) on the basis of spectroscopic data, chemical evidence, and/or X-ray analysis.
Tópico(s): Biological Activity of Diterpenoids and Biflavonoids
2003 - Pharmaceutical Society of Japan | Chemical and Pharmaceutical Bulletin
Tenji Konishi, Takao Konoshima, Yasuo Shimada, Shiu Kiyosawa,
Six new chromones, 6-methoxy-2-[2-(3-methoxy-4-hydroxyphenyl)ethyllchromone (2), 6,8-dihydroxy-2-(2-phenylethyl)chromone (3), 6-hydroxy-2-[2-(4-hydroxyphenyl)ethyl]chromone (4), 6-hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone (5), 7-hydroxy-2-(2-phenylethyl)chromone (6), and 6-hydroxy-7-methoxy-2-(2-phenylethyl)chromone (7) were isolated from the ether extract of agarwood in addition to a known compound, 2-(2-phenylethyl)chromone or flidersiachromone (1). Their structures were determined by spectroscopic ...
Tópico(s): Biological Stains and Phytochemicals
2002 - Pharmaceutical Society of Japan | Chemical and Pharmaceutical Bulletin
Tenji Konishi, Yasuo Shimada, Tsuneatsu Nagao, Hikaru Okabe, Takao Konoshima,
The MeOH extract of the roots of Inula helenium showed a high inhibitory activity for cell growth against MK-1, HeLa and B16F10 cell lines. Significant activity was found in the hexane-soluble fraction. From the hexane-soluble fraction, seven sesquiterpenes, namely, one germacrane (4beta,5alpha-epoxy-1(10),11(13)-germacradiene-8,12-olide), one elemane (igalane), and five eudesmanes (alantolactone, isoalantolactone, 11alpha,13-dihydroalantolactone, 11alpha,13-dihydro-isoalantolactone, 5-epoxyalantolactone) ...
Tópico(s): Natural product bioactivities and synthesis
2002 - Pharmaceutical Society of Japan | Biological and Pharmaceutical Bulletin
Tenji Konishi, Kiyonori Yamazoe, Takao Konoshima, Takashi Maoka, Yasuhiro Fujiwara, Kazumoto Miyahara,
Two new bis-secolabdane diterpenoids, excoecarins R1 (1) and R2 (2), were isolated from the resinous wood of Excoecaria agallocha. The structures of 1 and 2 were established on the basis of spectroscopic data interpretation and chemical evidence.
Tópico(s): Biological Control of Invasive Species
2002 - American Chemical Society | Journal of Natural Products
Takao Konoshima, Tenji Konishi, Midori Takasaki, Kiyonori Yamazoe, Harukuni Tokuda,
Eight new diterpenoids (1—8) have been isolated from the wood of Excoecaria agallocha (Euphorbiaceae) and their inhibitory effects on the induction of Epstein-Barr virus early antigen (EBV-EA) in Raji cells were examined to search for potent anti-tumor-promoters from natural resources. Of these compounds, the secolabdane-type diterpenoid, compound 7 exhibited a remarkable inhibitory effect on EBV-EA induction, and a significant anti-tumor-promoting effect in the mouse two-stage carcinogenesis test ...
Tópico(s): Natural Compounds in Disease Treatment
2001 - Pharmaceutical Society of Japan | Biological and Pharmaceutical Bulletin
Tenji Konishi, Yasuhiro Fujiwara, Takao Konoshima, Shiu Kiyosawa, Masatoshi Nishi, Kazumoto Miyahara,
Two steroidal saponins, hemeroside A and B, were isolated from the aerial part of Hemerocallis fulva var. kwanso for the first time. The structures of these compounds were established as 24S-hydroxy-neotokorogenin 1-O-alpha-L-arabinopyranosyl 24-O-beta-D-glucopyranoside (1) and isorhodeasapogenin 3-O-beta-D-glucopyranosyl-(1-->3)-[beta-D-xylopyranosyl-(1-->2)]-beta-D-glucopyranosyl-(1-->4)-beta-D-galactopyranoside (2) through NMR experiments.
Tópico(s): Natural product bioactivities and synthesis
2001 - Pharmaceutical Society of Japan | Chemical and Pharmaceutical Bulletin
Tópico(s): Urban and spatial planning
2000 - The Association of Teachers of Japanese | The Journal of the Association of Teachers of Japanese
Tenji Konishi, Takao Konoshima, Takashi Maoka, Yasuhiro Fujiwara,
Tópico(s): Essential Oils and Antimicrobial Activity
2000 - Elsevier BV | Tetrahedron Letters
Tenji Konishi, Takao Konoshima, Yasuhiro Fujiwara, Shiu Kiyosawa,
Three novel diterpenoids, excoecarins D, E, and K (1−3), were isolated from Excoecaria agallocha. The structures of 1−3 were established as 3α,18-dihydroxy-3β,20-epoxybeyer-15-ene, (15R,16S)-ent-15,16-epoxybeyeran-3-one, and ent-3β-hydroxykaur-16-en-2-one, respectively, on the basis of extensive NMR experiments and, in the case of 1, by X-ray analysis.
Tópico(s): Phytochemistry and Bioactive Compounds
2000 - American Chemical Society | Journal of Natural Products
Tenji Konishi, Takao Konoshima, Yasuhiro Fujiwara, Shiu Kiyosawa, Kazumoto Miyahara, Masatoshi Nishi,
Three new labdane-type diterpenes, excoecarins F, G1, and G2, were isolated from resinous wood of Excoecaria agallocha LINN collected from Okinawa prefecture. Stereochemistries of the new diterpenes were determined on the basis of chemical and physicochemical evidence. Excoecarin F was found to posses a chloride element in its structure.
Tópico(s): Phytochemistry and Bioactive Compounds
1999 - Pharmaceutical Society of Japan | Chemical and Pharmaceutical Bulletin
Tenji Konishi, Midori Takasaki, Harukuni Tokuda, SHU KIYOSAWA, Takao Konoshima,
To search for possible anti-tumor-promoters, we carried out the primary screening of seventeen diterpenes (1-17) isolated from the resinous wood of Excoecaria agallocha (Euphorbiaceae) using an in vitro synergistic assay system. Of these diterpenes, ent-16-hydroxy-3-oxo-13-epi-manoyloxide (5), (13R,14R)-ent-8alpha,13;14,15-diepoxy-13-epi- labda-3beta-ol (8) ent-3beta-hydroxy-15-beyeren-2-one (10) and ent-15-hydroxy-labda-8(17),13E-dien-3-one (14) exhibited significant inhibitory effects on Epstein-Barr ...
Tópico(s): Ginger and Zingiberaceae research
1998 - Pharmaceutical Society of Japan | Biological and Pharmaceutical Bulletin
Tenji Konishi, Yasuhiro Fujiwara, Takao Konoshima, Shiu Kiyosawa,
Five new labdane-type diterpenes were isolated from the resinous wood of Excoecaria agallocha. The structures of these compounds were established as ent-13-epi-8, 13-epoxy-2-hydroxylabda-1, 14-dien-3-one (1), ent-13-epi-8, 13-epoxy-14S, 15-dohydroxylabdan-3-one (2), ent-13-epi-8, 13-epoxy-2, 3-secolabd-14-ene-2, 3-dioic acid (3), ent-13-epi-8, 13-epoxy-2, 3-secolabd-14-ene-2, 3-dioic acid 3-methyl ester (4) and ent-13-epi-8, 13-epoxy-2-oxa-3-oxolabd-14-ene-1R-carboxylic acid (5).
Tópico(s): Traditional and Medicinal Uses of Annonaceae
1998 - Pharmaceutical Society of Japan | Chemical and Pharmaceutical Bulletin
Dervilla M. X. Donnelly, Tenji Konishi, Olive Dunne, Peadar Cremin,
Five new sesquiterpene aryl esters based on the Δ2, 3-protoilludane keleton were isolated from Armillaria tabescens grown in culture. These were characterized as 4-dehydro-14-hydroxydihydromelleolide, 4-dehydro-dihydromelleolide, 14-hydroxydihydromelleolide, 13-hydroxy-4-methoxymelleolide and 5β,10α-dihydroxy-1-orsellinate-dihydromelleolide. The structures of these compounds was established by collective NMR techniques.
Tópico(s): Phytochemistry and Bioactivity Studies
1997 - Elsevier BV | Phytochemistry
Tenji Konishi, Shiu Kiyosawa, Takao Konoshima, Yasuhiro Fujiwara,
Three new diterpenes, excoecarins A (2), B (3) and C (4) have been isolated from the wood of Excoecaria agallocha LINN. The structures of excoecarins A, B and C were established as (13R, 14R)-ent-8α, 13;14, 15-diepoxy-13-epi-labda-3-one (2), (13R, 14S)-ent-8α, 13;14, 15-diepoxy-13-epi-labda-3-one (3), (13R, 14R)-ent-8α, 13;14, 15-diepoxy-13-epi-labda-3β-ol (4), respectively, on the basis of spectroscopic data and chemical evidence.
Tópico(s): Natural Compounds in Disease Treatment
1996 - Pharmaceutical Society of Japan | Chemical and Pharmaceutical Bulletin
Tenji Konishi, Masuji AZUMA, Rie ITOGA, Shiu Kiyosawa, Yasuhiro Fujiwara, Yasuo Shimada,
From the wood of Excoecaria agallocha LINN., three new labdane-type diterpenes, ent-11α-hydroxy-3-oxo-13-epi-manoyl oxide (4), ent-16-hydroxy-3-oxo-13-epi-manoyl oxide (5) and ent-15-hydroxy-labda-8(17), 13E-diene-3-one (6) were isolated together with three known compounds, ent-3-oxo-13-epi-manoyl oxide (ribenone, 1), ent-3β-hydroxy-13-epi-manoyl oxide (ribenol, 2) and ent-13-epi-manoyl oxide (3), and their structures were determined.
Tópico(s): Biological Activity of Diterpenoids and Biflavonoids
1996 - Pharmaceutical Society of Japan | Chemical and Pharmaceutical Bulletin