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EDWARD PRICE BELL., ARMENEUS., PLUTARCH., ALFRED ROBBINS., DESMOND COKE., PHILIP E. PILDITCH., AUSTIN HOPKINSON., E. P. HEWITT., HENRY S. DAVENPORT., THOMAS ASHBY, EUGENIE STRONG.,

... Rector Of Clapham., Naval And Military, Señor Albert Gutierrez, formerly Bolivian, Viscount Peel has appointed Mr. S. ...

1922 - Gale Group | TDA

Artigo Revisado por pares

Joseph G. Cannon, Cecilia Suarez-Gutierrez, Teresa Lee, John P. Long, B. Costall, D. Fortune, Robert J. Naylor,

... peripheral and central effectsJoseph G. Cannon, Cecilia Suarez-Gutierrez, Teresa Lee, John Paul Long, Brenda Costall, David H. ...

Tópico(s): Synthesis and pharmacology of benzodiazepine derivatives

1979 - American Chemical Society | Journal of Medicinal Chemistry

Artigo Revisado por pares

Maria‐Teresa Gutierrez‐Lugo, Yuehong Wang, Scott G. Franzblau, Enrique Suárez, Barbara N. Timmermann,

... from Thalia multiflora Horkel ex Koernicke Maria-Teresa Gutierrez-Lugo, Maria-Teresa Gutierrez-Lugo Department of Pharmacology and Toxicology, Division ... for more papers by this author Maria-Teresa Gutierrez-Lugo, Maria-Teresa Gutierrez-Lugo Department of Pharmacology and Toxicology, Division of ...

Tópico(s): Traditional and Medicinal Uses of Annonaceae

2005 - Wiley | Phytotherapy Research

Carta Revisado por pares

Salvador Arias‐Santiago, María Teresa Gutiérrez‐Salmerón, A. Buendía‐Eisman, María Sierra Girón-Prieto, Ramón Naranjo‐Sintes,

... hotmail.esSearch for more papers by this authorMaría Teresa Gutiérrez-Salmerón PhD, María Teresa Gutiérrez-Salmerón PhD Dermatology Unit San Cecilio University Hospital ... hotmail.esSearch for more papers by this authorMaría Teresa Gutiérrez-Salmerón PhD, María Teresa Gutiérrez-Salmerón PhD Dermatology Unit San Cecilio University Hospital ...

Tópico(s): melanin and skin pigmentation

2010 - Wiley | International Journal of Dermatology

Carta Revisado por pares

Jesús Tercedor‐Sánchez, José M. Ródenas, M. Teresa Henraz, Valentin García‐Mellado, María Teresa Gutiérrez‐Salmerón, Ramón Naranjo,

... Granada, SpainSearch for more papers by this authorM. Teresa Gutierrez-Salmerón M.D., M. Teresa Gutierrez-Salmerón M.D. Granada, SpainSearch for more papers ... Granada, SpainSearch for more papers by this authorM. Teresa Gutierrez-Salmerón M.D., M. Teresa Gutierrez-Salmerón M.D. Granada, SpainSearch for more papers ...

Tópico(s): Chronic Lymphocytic Leukemia Research

1992 - Wiley | International Journal of Dermatology

Revisão Acesso aberto Revisado por pares

Maria‐Teresa Gutierrez‐Lugo, Carole A. Bewley,

... Small Molecules, and Genetics in Tuberculosis Drug DevelopmentMaria-Teresa Gutierrez-Lugo and Carole A. Bewley*View Author Information ...

Tópico(s): Biochemical and Molecular Research

2008 - American Chemical Society | Journal of Medicinal Chemistry

Artigo Revisado por pares

John Weeks,

... in Bruce Campbell, Andrew Jackson, Mehrene Larudee and Teresa Gutierrez Haces (eds.) Labour market effects under CUFTA/NAFTA. ... in Bruce Campbell, Andrew Jackson, Mehrene Larudee and Teresa Gutierrez Haces (eds.) Labour market effects under CUFTA/NAFTA. ...

Tópico(s): International Labor and Employment Law

1999 - Wiley | International Labour Review

Artigo Acesso aberto Revisado por pares

Ingrid Fricke-Galindo, Ivette Buendía-Roldán, Andy Ruíz, Yadira Palacios, Gloria Pérez‐Rubio, Rafael de Jesús Hernández-Zenteno, Felipe Reyes-Melendres, Armando Zazueta-Márquez, Aimé Alarcón-Dionet, Javier Guzmán-Vargas, Omar Andrés Bravo-Gutiérrez, Teresa Quintero-Puerta, Ilse Adriana Gutiérrez-Pérez, Karol J. Nava-Quiroz, José Luis Bañuelos-Flores, Mayra Mejía, Jorge Rojas‐Serrano, Espiridión Ramos-Martı́nez, Iris Paola Guzmán‐Guzmán, Leslie Chávez‐Galán, Ramcés Falfán‐Valencia,

Abstract Background The impact of genetic variants in the expression of tumor necrosis factor-α (TNF-α) and its receptors in coronavirus disease 2019 (COVID-19) severity has not been previously explored. We evaluated the association of TNF (rs1800629 and rs361525), TNFRSF1A (rs767455 and rs1800693), and TNFRSF1B (rs1061622 and rs3397) variants with COVID-19 severity, assessed as invasive mechanical ventilation (IMV) requirement, and the plasma levels of soluble TNF-α, TNFR1, and TNFR2 in patients with ...

Tópico(s): Respiratory Support and Mechanisms

2022 - Oxford University Press | The Journal of Infectious Diseases

Artigo Acesso aberto Revisado por pares

Pedro Garrido-Gutiérrez, Teresa Sánchez Chaparro, María Jesús Sánchez-Naranjo,

This article analyses students’ intention to use a particular e-learning technology (MS Teams) at university during the COVID-19 outbreak in Spain using the Unified Theory of Acceptance and Use of Technology (UTAUT). The model was refined through a qualitative analysis based on six focus group discussions with students from different engineering faculties in Madrid, Spain. A survey involving 346 undergraduate students was subsequently fed into the model. Structural Equation Modelling (SEM) and SMART ...

Tópico(s): Technology Adoption and User Behaviour

2023 - Multidisciplinary Digital Publishing Institute | Education Sciences

Revisão Acesso aberto Revisado por pares

Pilar Guadix, Isabel Corrales-Gutiérrez, Teresa Vilariño‐García, Carmen Rodríguez-Chacón, Flora Sánchez-Jiménez, Carlos Jiménez‐Cortegana, José L. Dueñas, Víctor Sánchez‐Margalet, Antonio Pérez‐Pérez,

Gestational diabetes mellitus (GDM) is the most frequent pathophysiological state of pregnancy, which in many cases produces fetuses with macrosomia, requiring increased nutrient transport in the placenta. Recent studies by our group have demonstrated that leptin is a key hormone in placental physiology, and its expression is increased in placentas affected by GDM. However, the effect of leptin on placental nutrient transport, such as transport of glucose, amino acids, and lipids, is not fully understood. ...

Tópico(s): Birth, Development, and Health

2023 - Frontiers Media | Frontiers in Endocrinology

Artigo Revisado por pares

Mendoza Enciso Emmanuel Antonio, Carolina C. Barajas-García, Rodriguez Jimenez Dante Emiliano, Ortiz Lopez Margarita Guadalupe, Reza Escalera Ana Lilian, Tiscareño Gutiérrez María Teresa, Gonzalez Gamez Mario, Rodríguez Correa Gustavo Ivan, Ramos Velazco Mercedes, Chew Wong Alfredo, Reyes Acevedo Rafael, Guerrero Barrera Alma Lilian, María José Guerra Palmero,

The incidence of urinary tract infections (UTIs) in the first 2 months postrenal transplantation (pRT) is very high. We evaluate the efficacy of asymptomatic bacteriuria (AB) screening and treatment on the incidence of UTI in the first 2 months pRT METHODS: We conducted a randomized controlled clinical trial. A urine culture was obtained in all patients on the day of the bladder catheter removal, on week three, and before removal of the ureteral catheter. The intervention group received treatment for ...

Tópico(s): Kidney Stones and Urolithiasis Treatments

2022 - Wiley | Transplant Infectious Disease

Artigo Acesso aberto Revisado por pares

Jofre Carnicer, Maria Vives‐Ingla, Laura Blanquer, Xavier Méndez‐Camps, Carme Rosell, Santiago Sabaté, Emília Gutiérrez, Teresa Sauras‐Yera, Josep Peñuelas, Adrià Barbeta,

Abstract Resilience of endangered rear edge populations of cold‐adapted forests in the Mediterranean basin is increasingly altered by extreme heatwave and drought pressures. It remains unknown, however, whether microclimatic variation in these isolated forests could ultimately result in large intra‐population variability in the demographic responses, allowing the coexistence of contrasting declining and resilient trends across small topographic gradients. Multiple key drivers promoting spatial variability ...

Tópico(s): Fire effects on ecosystems

2021 - Wiley | Journal of Ecology

Artigo Acesso aberto Revisado por pares

Andrea Guala, Lydia Dux‐Santoy, Gisela Teixidó‐Turà, Aroa Ruiz‐Muñoz, Laura Galián-Gay, Maria Luz Servato, Filipa Valente, L Gutiérrez, Teresa González‐Alujas, Kevin M. Johnson, Oliver Wieben, G Casas-Masnou, Augusto Sao Avilés, R Fernandez-Galera, Ignacio Ferreira‐González, Arturo Evangelista, José F. Rodríguez‐Palomares,

This study sought to assess the predictive value of wall shear stress (WSS) for colocalized ascending aorta (AAo) growth rate (GR) in patients with bicuspid aortic valve (BAV).BAV is associated with AAo dilation, but there is limited knowledge about possible predictors of aortic dilation in patients with BAV. An increased WSS has been related to aortic wall damage in patients with BAV, but no previous prospective study tested its predictive value for dilation rate. Recently, a registration-based technique ...

Tópico(s): Aortic aneurysm repair treatments

2021 - Elsevier BV | JACC. Cardiovascular imaging

Artigo

M Eugène, Piotr Duchnowski, Bernard Prendergast, Olaf Wendler, Cécile Laroche, Jean‐Luc Monin, Yannick Jobic, Bogdan A. Popescu, Jeroen J. Bax, Alec Vahanian, Bernard Iung, Bernard Iung, Jeroen J. Bax, Michele De Bonis, Victoria Delgado, Michael Haude, Gerhard Hindricks, Aldo P. Maggioni, Luc Piérard, Bogdan A. Popescu, Bernard Prendergast, Susanna Price, Raphaël Rosenhek, Frank Ruschitzka, Alec Vahanian, Olaf Wendler, Stephan Windecker, Souad Mekhaldi, Katell Lemaitre, Sébastien Authier, Cécile Laroche, Aldo P. Maggioni, Magdy Abdelhamid, Astrid Apor, Gani Bajraktari, Branko Beleslin, Alexander Bogachev‐Prokophiev, Daniela Cassar Demarco, Agnès Pasquet, Victoria Delgado, Sait Mesut Doğan, Andrejs Ērglis, Arturo Evangelista, A Goda, Nikolaj Ihlemann, Hüseyin İnce, Andreas Katsaros, Kateřina Linhartová, Julia Mascherbauer, Erkin М Мirrakhimov, Vaida Mizarienė, Bogdan A. Popescu, Shelley Rahman-Haley, Regina Ribeiras, Fuad Samadov, Antti Saraste, Iveta Šimková, Elizabeta Srbinovska Kostovska, Lidia Tomkiewicz‐Pająk, Christophe Tribouilloy, E Zëra, Mimoza Metalla, A Goda, E Shirka, E Dado, Loreta Bica, Jorida Aleksi, G Knuti, Lidra Gjyli, R Pjeci, E Shuperka, Erviola Lleshi, Joana Rustemaj, M Qordja, Mirald Gina, Senada Husi, Daniel Basic, Regina Steringer‐Mascherbauer, Charlotte Huber, Christian Ebner, Elisabeth Sigmund, Andrea Ploechl, Thomas Sturmberger, Veronica Eder, Tanja Koppler, Julia Mascherbauer, Maria Heger, Andreas A. Kammerlander, Franz Duca, Christina Binder, Matthias Koschutnik, Leonard Perschy, L Puskas, Chen‐Yu Ho, Farid Aliyev, Vugar Guluzada, Galib Imanov, Firdovsi İbrahimov, Abbasali Abbasaliyev, Tahir Ahmedov, Fargana Muslumova, Jamil Babayev, Yasmin Rustamova, Tofig Jahangirov, Rauf Samadov, Fuad Samadov, Muxtar Museyibov, Elnur İsayev, Oktay Musayev, Shahin Xalilov, Saleh Huseynov, Madina Yuzbashova, Vuqar Zamanov, Vusal Mammadov, Gery Van Camp, Martin Pěnička, H Batjoens, Philippe Debonnaire, Daniel Jp Dendooven, Sébastien Knecht, Mattias Duytschaever, Yves Vandekerckhove, Luc Missault, Luc Muyldermans, René Tavernier, Tineke De Grande, Patrick Coussement, Joyce DeTroyer, K. Derycker, Kelly De Jaegher, Antoine Bondue, Christophe Beauloye, Céline Goffinet, Daniela Corina Mirica, Antoine Bondue, Frédéric Vanden Eynden, Philippe van de Borne, B. van Frachen, David Vancraeynest, Jean‐Louis Vanoverschelde, Sophie Piérard, Mihaela Malanca, F Sinnaeve, S. Tahon, Marie De Clippel, Frederic Gayet, Jacques Loiseau, Nico Van de Veire, Veronique Moerman, Anne‐Marie Willems, Bernard Cosyns, Steven Droogmans, Andreea Motoc, D. Kerkhove, Danièle Plein, Bram Roosens, Caroline Weytjens, Patrizio Lancellotti, Luc Piérard, Elena Dulgheru, Ilona Pařenicová, Helena Bedáňová, František Toušek, S Sindelárová, Júlia Čanádyová, Miloš Táborský, Jiří Ostřanský, Iveta Šimková, Marek Vícha, Libor Jelínek, Irena Opavská, Miroslav Homza, Miriam Kvrayola, Radim Brát, Dan Mrozek, Eva Lichnerová, Iveta Docekalova, Kateřina Linhartová, Marta Zárybnická, M. Pešková, Patrik Roučka, Vlasta Šťastná, Dagmar Jungwirtova Vondrackova, Alfred Hornig, Matúš Nižňanský, Marian Branny, Alexandra Vodzinská, Miloslav Dorda, Libor Snkouril, Krystyna Kluz, Jana Kypusova, Radka Nezvalova, Nikolaj Ihlemann, Niels Thue Olsen, Hosam Hasan Ali, Salma Taha, Mohamed Hassan, Ahmed Afifi, Hamza Kabil, Amr Mady, Hany Ebaid, Yasser A. Ahmed, Mohammad Ghasemi Nour, Islam Talaat, CairoMaiy El Sayed, Ahmad E. Mostafa, C. Sadek, CairoSherif Eltobgi, Magdy Abdelhamid, Sameh Bakhoum, Ramy Doss, Mahmoud Sheashea, Abd Allah Elasry, Ahmed Fouad, Mahmoud Baraka, Sameh Samir, Alaa Mahmoud Roshdy, Yasser Arafat Abdelrazek, M M Abd Rabou, Ahmed M. Abo‐Bakr, M Moaaz, Mohamed Mokhtar Mohamed, Mohamed Ashry, Khaled Elkhashab, Haytham Soliman Ghareeb, Mostafa Kamal, Gomaa Abdelrazek, GizaNabil Farag, Giza Ahmed Elbarbary, Evette Wahib, Ghada Kazamel, Diaa Kamal, Ahmad E. Mostafa, Mahmoud Tantawy, Adel Alansary, Mohammed Yahia, Raouf Mahmoud, Tamer El Banna, Mohamed Atef, Gamela Nasr, Ahmed Salah, Ehab E. El Hefny, Islam Saifelyazal, Mostafa Abd El Ghany, Abd El Rahman El Hadary, Ahmed Khairy, Jyri Lommi, Mika Laine, Minna Kylmälä, Katja Kankanen, Mika Laine, Anu Turpeinen, Juha Hartikainen, Lari Kujanen, Juhani Airaksinen, Antti Saraste, Tuija Vasankari, Christophe Tribouilloy, Catherine Szymanski, Yohann Bohbot, Mesut Gun, Justine Rousseaux, Loïc Bière, Victor Mateus, Martin Audonnet, Jérémy Rautureau, Charles Cornet, Emmanuel Sorbets, BourgesKarine Mear, Adi Issa, Yannick Jobic, Florent Le Ven, Marie-Claire Pouliquen, Martine Gilard, Alice Ohanessian, Martin Audonnet, Ali Farhat, Alina Vlase, Fkhar Said, Caroline Lasgi, Carlos E. Sanchez, R. Breil, Marc Peignon, Jean-Philippe Elkaïm, Virginie Jan-Blin, Sylvain Ropars BertrandM'Ban, Hélène Bardet, Samuel Sawadogo, Aurélie Muschoot, Dieudonné Tchatchoua, Simon Elhadad, Aline Maubert, Victor Mateus, Tahar Lazizi, Kais Ourghi, Philippe Bonnet,

There were gaps between guidelines and practice when surgery was the only treatment for aortic stenosis (AS). This study analyzed the decision to intervene in patients with severe AS in the EORP VHD (EURObservational Research Programme Valvular Heart Disease) II survey. Among 2,152 patients with severe AS, 1,271 patients with high-gradient AS who were symptomatic fulfilled a Class I recommendation for intervention according to the 2012 European Society of Cardiology guidelines; the primary end point ...

Elsevier BV

Artigo Revisado por pares

Andrea Guala, Gisela Teixidó‐Turà, José F. Rodríguez‐Palomares, Aroa Ruiz‐Muñoz, Lydia Dux‐Santoy, N. Villalva, Chiara Granato, Laura Galián-Gay, L Gutiérrez, Teresa González‐Alujas, Violeta Sánchez, Alberto Forteza, David García‐Dorado, Artur Evangelista,

Abstract Aims Life expectancy in Marfan syndrome patients has improved thanks to the early detection of aortic dilation and prophylactic aortic root surgery. Current international clinical guidelines support the use of aortic root diameter as a predictor of complications. However, other imaging markers are needed to improve risk stratification. This study aim to ascertain whether proximal aorta longitudinal and circumferential strain and distensibility assessed by cardiac magnetic resonance (CMR) ...

Tópico(s): Cardiac Valve Diseases and Treatments

2019 - Oxford University Press | European Heart Journal

Artigo Acesso aberto Revisado por pares

Raymond Salvador, Erick J. Canales‐Rodríguez, Amalia Guerrero‐Pedraza, Salvador Sarró, Diana Tordesillas‐Gutiérrez, Teresa Maristany, Benedicto Crespo‐Facorro, Peter J. McKenna, Edith Pomarol‐Clotet,

Magnetic resonance imaging (MRI) has been proposed as a source of information for automatic prediction of individual diagnosis in schizophrenia. Optimal integration of data from different MRI modalities is an active area of research aimed at increasing diagnostic accuracy. Based on a sample of 96 patients with schizophrenia and a matched sample of 115 healthy controls that had undergone a single multimodal MRI session, we generated individual brain maps of gray matter vbm, 1back, and 2back levels ...

Tópico(s): Neural dynamics and brain function

2019 - Frontiers Media | Frontiers in Neuroscience

Revisão Acesso aberto Revisado por pares

Domingo Hernández, Juana Alonso-Titos, Ana María Armas-Padrón, Verónica López, Mercedes Cabello, E. Solá, Laura Fuentes, Elena Gutiérrez, Teresa Vázquez, Tamara Jiménez, Pedro Ruiz‐Esteban, M. González-Molina,

Chronic kidney disease (CKD) is an important independent risk factor for adverse cardiovascular events in patients waitlisted for kidney transplantation (KT). Although KT reduces cardiovascular risk, these patients still have a higher all-cause and cardiovascular mortality than the general population. This concerning situation is due to a high burden of traditional and nontraditional risk factors as well as uremia-related factors and transplant-specific factors, leading to 2 differentiated processes ...

Tópico(s): Chronic Kidney Disease and Diabetes

2019 - Karger Publishers | Kidney & Blood Pressure Research

Artigo Revisado por pares

Lydia Dux‐Santoy, Andrea Guala, Gisela Teixidó‐Turà, Aroa Ruiz‐Muñoz, Giuliana Maldonado, N. Villalva, Laura Galián-Gay, Filipa Valente, L Gutiérrez, Teresa González‐Alujas, Augusto Sao‐Avilés, Kevin M. Johnson, Oliver Wieben, Marina Huguet, David García‐Dorado, Arturo Evangelista, José F. Rodríguez‐Palomares,

Abstract Aims Aortic dilation in bicuspid aortic valve (BAV) might extend to the proximal arch. Arch flow dynamics and their relationship with this segment dilation are still unexplored. Using 4D-flow cardiovascular magnetic resonance, we analysed flow dynamics in the arch for each BAV morphotype and their association with this segment dilation. Methods and results One hundred and eleven BAV patients (aortic diameters ≤55 mm, non-severe valvular disease), 21 age-matched tricuspid aortic valve (TAV) ...

Tópico(s): Aortic aneurysm repair treatments

2019 - Oxford University Press | European Heart Journal - Cardiovascular Imaging

Artigo Acesso aberto Revisado por pares

Rafael Simó, Jordi Bañeras, Cristina Hernández, José F. Rodríguez‐Palomares, Filipa Valente, Laura Gutiérrez, Teresa González‐Alujas, Ignacio Ferreira, Santiago Aguadé‐Bruix, Joan Montaner, Daniel Serón, Joan Genescà, Anna Boixadera, José García‐Arumí, Alejandra Planas, Olga Simó‐Servat, David García‐Dorado,

Objective Detection of subclinical cardiovascular disease (CVD) has significant impact on the management of type 2 diabetes. We examined whether the assessment of diabetic retinopathy (DR) is useful for identifying patients at a higher risk of having silent CVD. Research design and methods Prospective case–control study comprising 200 type 2 diabetic subjects without history of clinical CVD and 60 age-matched non-diabetic subjects. The presence of subclinical CVD was examined using two parameters: ( ...

Tópico(s): Cerebrovascular and Carotid Artery Diseases

2019 - BMJ | BMJ Open Diabetes Research & Care

Artigo Acesso aberto Revisado por pares

Marta Sancho, Marta de Gracia, Roser Granero, Sara González-Simarro, Isabel Sánchez, Fernando Fernández‐Aranda, Joan Trujols, Núria Mallorquí‐Bagué, Gemma Mestre‐Bach, Amparo del Pino‐Gutiérrez, Teresa Mena-Moreno, Cristina Vintró‐Alcaraz, Trevor Steward, Neus Aymamí, Mónica Gómez‐Peña, José M. Menchón, Susana Jiménez‐Múrcia,

Introduction: Impairments in emotion regulation are understood to be a transdiagnostic risk factor of suffering from compulsive and addictive behaviors. The aim of this study was to investigate the role of emotion regulation deficits in gambling disorder and to analyze these differences taking gender, age and gambling activity preferences into account. Methods: The sample included n=484 patients seeking treatment for gambling disorder at a specialized outpatient service. Main outcomes were socio- ...

Tópico(s): Eating Disorders and Behaviors

2019 - Frontiers Media | Frontiers in Psychiatry

Artigo Acesso aberto Revisado por pares

Andrea Guala, Gisela Teixidó‐Turà, Lydia Dux‐Santoy, Chiara Granato, Aroa Ruiz‐Muñoz, F Valente, Laura Galián-Gay, L Gutiérrez, Teresa González‐Alujas, Kevin M. Johnson, Oliver Wieben, Augusto Sao Avilés, Artur Evangelista, José F. Rodríguez‐Palomares,

Diseases of the descending aorta have emerged as a clinical issue in Marfan syndrome following improvements in proximal aorta surgical treatment and the consequent increase in life expectancy. Although a role for hemodynamic alterations in the etiology of descending aorta disease in Marfan patients has been suggested, whether flow characteristics may be useful as early markers remains to be determined. Seventy-five Marfan patients and 48 healthy subjects were prospectively enrolled. In- and through- ...

Tópico(s): Aortic aneurysm repair treatments

2019 - BioMed Central | Journal of Cardiovascular Magnetic Resonance

Revisão Acesso aberto Revisado por pares

Pedro-Luis Sanchez-Gonzalez, David Díaz Gutiérrez, Teresa J. Leo, Luis R. Núñez-Rivas,

Although maritime transport is the backbone of world commerce, its digitalization lags significantly behind when we consider some basic facts. This work verifies the state-of-the-art as it currently applies to eight digital domains: Autonomous vehicles and robotics; artificial intelligence; big data; virtual reality, augmented and mixed reality; internet of things; the cloud and edge computing; digital security; and 3D printing and additive engineering. It also provides insight into each of the ...

Tópico(s): International Maritime Law Issues

2019 - Multidisciplinary Digital Publishing Institute | Sensors

Artigo Acesso aberto Revisado por pares

Dimitrios Evangelopoulos, Gareth A. Prosser, Angela Rodgers, Belinda Dagg, Bhagwati Khatri, Mei Mei Ho, Maximiliano G. Gutiérrez, Teresa Cortes, Luiz Pedro S. de Carvalho,

Abstract Drug resistant infections represent one of the most challenging medical problems of our time. D -cycloserine is an antibiotic used for six decades without significant appearance and dissemination of antibiotic resistant strains, making it an ideal model compound to understand what drives resistance evasion. We therefore investigated why Mycobacterium tuberculosis fails to become resistant to D -cycloserine. To address this question, we employed a combination of bacterial genetics, genomics, ...

Tópico(s): Tuberculosis Research and Epidemiology

2019 - Nature Portfolio | Nature Communications

Artigo Acesso aberto Revisado por pares

Lydia Dux‐Santoy, Andrea Guala, Julio Sotelo, Sergio Uribe, Gisela Teixidó‐Turà, Aroa Ruiz‐Muñoz, Daniel E. Hurtado, Filipa Valente, Laura Galián-Gay, L Gutiérrez, Teresa González‐Alujas, Kevin M. Johnson, Oliver Wieben, Ignacio Ferreira‐González, Arturo Evangelista, José F. Rodríguez‐Palomares,

To assess the relationship between regional wall shear stress (WSS) and oscillatory shear index (OSI) and aortic dilation in patients with bicuspid aortic valve (BAV). Approach and Results: Forty-six consecutive patients with BAV (63% with right-left-coronary-cusp fusion, aortic diameter ≤ 45 mm and no severe valvular disease) and 44 healthy volunteers were studied by time-resolved 3-dimensional phase-contrast magnetic resonance imaging. WSS and OSI were quantified at different levels of the ascending ...

Tópico(s): Coronary Artery Anomalies

2019 - Lippincott Williams & Wilkins | Arteriosclerosis Thrombosis and Vascular Biology

Artigo Revisado por pares

Andrea Guala, José F. Rodríguez‐Palomares, Lydia Dux‐Santoy, Gisela Teixidó‐Turà, Giuliana Maldonado, Laura Galián-Gay, Marina Huguet, Filipa Valente, L Gutiérrez, Teresa González‐Alujas, Kevin M. Johnson, Oliver Wieben, Augusto Sao Avilés, David García‐Dorado, Arturo Evangelista,

This study sought to ascertain whether patients with a bicuspid aortic valve (BAV) have an intrinsic alteration in regional aortic stiffness compared with patients with tricuspid aortic valve (TAV) and Marfan syndrome (MFS) patients with similar aortic sizes, as well as to assess the influence of ascending aorta (AAo) dilation on regional stiffness parameters in BAV patients. Imaging biomarkers as predictors of BAV, MFS, and degenerative AAo aneurysms in TAV patients (DA-TAV) are lacking. Biomechanical ...

Tópico(s): Cardiac Valve Diseases and Treatments

2018 - Elsevier BV | JACC. Cardiovascular imaging

Artigo Acesso aberto Revisado por pares

Victoria Gil, Miguel Ángel Gaertner, Claudia Gutiérrez, Teresa Losada,

As solar energy will be an increasingly important renewable energy source in future years, the study of how climate change affects both its temporal and spatial variability is very relevant. In this paper, we study future changes of the solar radiation resource in the Iberian Peninsula (IP) through a set of simulations from ESCENA project (generation of regionalized scenarios of climate change in Spain with high‐resolution models) until mid‐century. The evaluation of the simulations against observations ...

Tópico(s): Social Acceptance of Renewable Energy

2018 - Wiley | International Journal of Climatology

Revisão Acesso aberto Revisado por pares

José Marı́a Gutiérrez, Teresa Escalante, Rosario Lunar Hernández, Stefano Gastaldello, Patricia Saravia‐Otten, Alexandra Rucavado,

Skeletal muscle regeneration after myonecrosis involves the activation, proliferation and fusion of myogenic cells, and a coordinated inflammatory response encompassing phagocytosis of necrotic cell debris, and the concerted synthesis of cytokines and growth factors. Myonecrosis often occurs in snakebite envenomings. In the case of venoms that cause myotoxicity without affecting the vasculature, such as those of many elapid snakes, regeneration proceeds successfully. In contrast, in envenomings ...

Tópico(s): Calpain Protease Function and Regulation

2018 - Multidisciplinary Digital Publishing Institute | Toxins

Artigo Revisado por pares

Jeroen C. Vis, José F. Rodríguez‐Palomares, Gisela Teixidó‐Turà, Laura Galián-Gay, Chiara Granato, Andrea Guala, Augusto Sao‐Avilés, L Gutiérrez, Teresa González‐Alujas, David García‐Dorado, Arturo Evangelista,

•In patients with BAVs, TTE slightly underestimated aortic root diameter. •In BAV, aortic diameter differences by TTE and MRI are ≥3 mm in 39% of cases. •Root asymmetry increases aortic root diameter differences between TTE and MRI in BAV. •In BAV-RN, underestimation of aortic root diameter may be significant. •TTE-PSAX helps in root asymmetry diagnosis but has low diameter reproducibility. Background Transthoracic echocardiography (TTE) and magnetic resonance imaging (MRI) have yielded excellent results ...

Tópico(s): Coronary Artery Anomalies

2018 - Elsevier BV | Journal of the American Society of Echocardiography