... Mushi Productions, Osamu Tezuka. Used by permission of Tezuka Productions Co., Ltd. All rights reserved. [End Page 314] ...
Tópico(s): Japanese History and Culture
2013 - University of Minnesota Press | Mechademia Second Arc
Eishin Morita, Yoshikazu Kameyoshi, Takaaki Hiragun, Shoji Mihara, S. Yamamoto,
... Matsukura M, Yudate T, Chihara J, Stingl G & Tezuka T. Enhanced production of RANTES, an eosinophil chemoattractant factor, by cytokine- ...
Tópico(s): Asthma and respiratory diseases
2001 - Wiley | Allergy
... insects) (Tokyo: Kōdansha, 1998). Used by permission of Tezuka Productions Co., Ltd. All rights reserved. Click for larger ... insects) (Tokyo: Kodansha, 1998). Used by permission of Tezuka Productions Co., Ltd. All rights reserved. [End Page 74] ... Tezuka Manga Complete Works. Used by permission of Tezuka Productions Co., Ltd. All rights reserved. Click for larger ... Tezuka Manga Complete Works. Used by permission of Tezuka Productions Co., Ltd. All rights reserved. dressed in the uniform of the insect hunter: khakis, a white button-up shirt, and a beige hat. He holds the requisite butterfly net and has an insect cage handle slung over his belt. Above the photo is a quote attributed to Tezuka, a textbook example of the causative verb that ...
Tópico(s): Cancer-related Molecular Pathways
2013 - University of Minnesota Press | Mechademia Second Arc
... and local tastes-and despite the involvement of Tezuka Productions, a company entrusted with preserving the creator's ... in Takarazuka in 2011. Used by permission of Tezuka Productions Co., Ltd. All rights reserved. [End Page 281] with the exhibition, Tezuka was connected ever more intimately to Akihabara as ...
Tópico(s): Cinema and Media Studies
2013 - University of Minnesota Press | Mechademia Second Arc
... concerns, Suzuki et al. (2018)3Suzuki N. Matsuo-Tezuka Y. Sasaki Y. et al.Iron attenuates erythropoietin production by decreasing hypoxia-inducible transcription factor 2α concentrations ...
Tópico(s): Iron Metabolism and Disorders
2018 - Elsevier BV | Kidney International
... 5. Dreams of Export: Toei Doga and MOM Production 1953-67.- 6. Warrior Business: Tezuka's Anime Revolution in Context 1961-67.- 7. ...
Tópico(s): Asian Culture and Media Studies
2014 - Association of College and Research Libraries | Choice Reviews Online
... culture. Graziano Krätli North Haven, Connecticut Toshio Ban & Tezuka Productions. The Osamu Tezuka Story: A Life in Manga and Anime. Trans. ...
Tópico(s): Comics and Graphic Narratives
2017 - University of Oklahoma | World Literature Today
... idleness), showing obi wrapper. Used by permission of Tezuka Productions Co., Ltd. All rights reserved. It might be Okumoto's profession as a French literature expert that leads him to look to foreign authors such as Victor Hugo or Balzac to find one with Tezuka's scope and precociousness.4 These are no ...
Tópico(s): Cultural, Media, and Literary Studies
2013 - University of Minnesota Press | Mechademia Second Arc
Ryu-ich Fukuda, Kiyohito Tsuchiya, Koji Suzuki, Katsuhiko Itoh, Jun Fujita, Atae Utsunomiya, Takashi Tsuji,
... Chem... 2006; 281: 8927-8938Google Scholar, 26Okamoto N. Tezuka K. Kato M. Abe R. Tsuji T. Biochem. Biophys. Res. Commun... 2003; 310: 691-702Google Scholar). However, how Tax modulates PIP3 production and the mechanism of Akt signaling activation has ...
Tópico(s): Animal Disease Management and Epidemiology
2008 - Elsevier BV | Journal of Biological Chemistry
... competition evaluated on group rather than individual performance. Tezuka sees major problems with the three elements. The severe competition among companies has led to overinvestment in production capacity. The competition has held down operating profits, accelerated the speed of product development, and shortened product life. It has also raised the entry barriers for non-Japanese firms. Tezuka predicts that the system in its current form ...
Tópico(s): Globalization, Economics, and Policies
1997 - Elsevier BV | Sloan management review
... There are, however, some dissenters who argue that Tezuka could never have created his animation company Mushi Production (Mushi Pro) so swiftly were it not for ... so by the strictures of the Astro Boy production.10 At no point, however, did Tezuka define what this notional "anime" actually was. His ...
Tópico(s): Digital Games and Media
2013 - University of Minnesota Press | Mechademia Second Arc
Tatsuya Koyama, Yoshikazu Nakaoka, Yasushi Fujio, Hisao Hirota, Keigo Nishida, Shoko Sugiyama, Kitaro Okamoto, Keiko Yamauchi‐Takihara, Michihiro Yoshimura, Seibu Mochizuki, Masatsugu Hori, Toshio Hirano, Naoki Mochizuki,
... T. Ohtani T. Shirogane T. Atsumi T. Takahashi-Tezuka M. Ishihara K. Hibi M. Hirano T. Blood. 1999; 93: 1809-1816Crossref PubMed Google Scholar). For adenovirus production, the sequence encoding Gab1Δp85, SHP2WT, or SHP2C/S ...
Tópico(s): Cytokine Signaling Pathways and Interactions
2008 - Elsevier BV | Journal of Biological Chemistry
Emma H. Wilson, Christopher A. Hunter,
... J Biol Chem 2000; 276: 46118–46124. 43 Tezuka H, Imai S, Tsukidate S & Fujita K. A Dirofilaria immitis polyprotein up-regulates nitric oxide production. Infect Immun 2002; 70: 5283–5286. 44 Van ...
Tópico(s): T-cell and B-cell Immunology
2003 - Wiley | Parasite Immunology
... years, has not produced a figure such as Tezuka Osamu. Some analyses suggest that South Korean audiences do not accept animation. 6 Nevertheless, owing to decades of active production, South Korea’s animation industry eventually attracted the ...
Tópico(s): Asian Industrial and Economic Development
2014 - University of Minnesota Press | Mechademia Second Arc
Naokazu Okamoto, Katsunari Tezuka, Masako Kato, Ryo Abe, Takashi Tsuji,
Both AILIM/ICOS and CD28 provide positive costimulatory signals for T-cell activation, resulting in proliferation and cytokine production. In this study, we attempted to clarify the key signaling molecules in T-cell proliferation, and also IL-2 and IL-10 production, during T-cell activation by CD3 induced by costimulation with either AILIM/ICOS or CD28. We examined the role of both the PI3-kinase/Akt pathway and MAP kinase family members such as ERK1/2, JNK, and p38 kinase in this process. PI3-kinase ...
Tópico(s): Cytokine Signaling Pathways and Interactions
2003 - Elsevier BV | Biochemical and Biophysical Research Communications
... per year, it soon outpaced the original manga production. Tezuka had to create new stories exclusive to the ...
Tópico(s): Art, Technology, and Culture
2013 - University of Minnesota Press | Mechademia Second Arc
Hiroyuki Tezuka, Shinjiro Imai, Setsuko Tsukidate, Koichirô Fujita,
ABSTRACT We investigated the effect of recombinant Dirofilaria immitis polyprotein (rDiAg) on nitric oxide (NO) production by peritoneal macrophages. rDiAg induced NO production by macrophages from wild-type and lipopolysaccharide-hyporesponsive C3H/HeJ, but not CD40 −/− , mice. These results suggest that CD40 is involved in rDiAg-driven NO production by murine macrophages.
Tópico(s): Invertebrate Immune Response Mechanisms
2002 - American Society for Microbiology | Infection and Immunity
... behind large round glasses (Figure 1), likewise animated Tezuka the man, as his signature and in the logo for Mushi Productions. Of the more than 700 manga he produced in his lifetime, as many as 180 had insects in them.3 It is no exaggeration to say that insects inspired Tezuka Osamu's own "Manga Life," and that his ...
Tópico(s): Animal and Plant Science Education
2013 - University of Minnesota Press | Mechademia Second Arc
Hiroyuki Tezuka, Toshiaki Ohteki,
The intestinal mucosa is a physiological barrier for most microbes, including both commensal bacteria and invading pathogens. Under homeostatic conditions, immunoglobulin A (IgA) is the major immunoglobulin isotype in the intestinal mucosa. Microbes stimulate the production of IgA, which controls bacterial translocation and neutralizes bacterial toxins at the intestinal mucosal surface. In the intestinal mucosa, dendritic cells (DCs), specialized antigen-presenting cells, regulate both T-cell-dependent ( ...
Tópico(s): T-cell and B-cell Immunology
2019 - Frontiers Media | Frontiers in Immunology
Mio Hori, Seishi Kishimoto, Yu Tezuka, Hideo Nishigori, Keitaro Nomoto, Umenoi Hamada, Yoshikazu Yonei,
Objective: To determine the effect of beet extract on skin elasticity in female volunteers with dry skin and in human dermal fibroblasts.Method: To assess the effects of oral administration of glucosyl ceramide contained in beet extract (beet ceramide), we conducted an 8-week double-blind comparison study with 35 females (mean age: 40.9±4.2 years) with mild subjective symptoms of dry skin and declining keratin moisture levels. The compound was administered as glucosyl ceramide at 0, 0.6, or 1.8 mg/ ...
Tópico(s): Polysaccharides and Plant Cell Walls
2010 - | ANTI-AGING MEDICINE
... product producers, "Atomu no kai" (The Atomu Association), Tezuka and his Mushi Production studio effectively differentiated between good, licensed [End Page ... Yet even amid this economically beneficial situation to Tezuka, wherein Atomu goods were bringing much needed cash to pay for the loss-making animation production business, there was something in the proliferation of Atomu images that would begin to cause Tezuka...
Tópico(s): Japanese History and Culture
2013 - University of Minnesota Press | Mechademia Second Arc
... action elements in a detailed performance analysis of TeZukA (2011) by choreographer Sidi Larbi Cherkaoui. This dance theatre production enacts the life story of Osamu Tezuka and some of his famous manga characters, interweaving ...
Tópico(s): Theatre and Performance Studies
2015 - | Networking Knowledge Journal of the MeCCSA Postgraduate Network
Takashi Kondo, Hironori Tezuka, Jun Ishii, Fumio Matsuda, Chiaki Ogino, Akihiko Kondo,
The production of higher alcohols by engineered bacteria has received significant attention. The budding yeast, Saccharomyces cerevisiae, has considerable potential as a producer of higher alcohols because of its capacity to naturally fabricate fusel alcohols, in addition to its robustness and tolerance to low pH. However, because its natural productivity is not significant, we considered a strategy of genetic engineering to increase production of the branched-chain higher alcohol isobutanol, which ...
Tópico(s): Fungal and yeast genetics research
2012 - Elsevier BV | Journal of Biotechnology
Hiroyuki Tezuka, Yukiko Abe, Makoto Iwata, Hajime Takeuchi, Hiromichi Ishikawa, Masayuki Matsushita, Tetsuo Shiohara, Shizuo Akira, Toshiaki Ohteki,
Tópico(s): T-cell and B-cell Immunology
2007 - Nature Portfolio | Nature
Yutaka Arimura, Fumiko Shiroki, Shingo Kuwahara, Hidehito Kato, Umberto Dianzani, Takehiko Uchiyama, Junji Yagi,
... 3083-3091PubMed Google Scholar) or AILIM (10Tamatani T. Tezuka K. Hanzawa-Higuchi N. Int. Immunol. 2000; 12: 51-55Crossref PubMed Scopus (46) Google Scholar), is a member of the CD28 family and has roles similar to those of CD28 except for IL-2 production (11Hutloff A. Dittrich A.M. Beier K.C. ...
Tópico(s): PI3K/AKT/mTOR signaling in cancer
2004 - Elsevier BV | Journal of Biological Chemistry
Yasuhiro Tezuka, Shiho Irikawa, T. Kaneko, Arjun H. Banskota, Takema Nagaoka, Quanbo Xiong, Koji Hase, Shigetoshi Kadota,
Sixty-eight water and methanol extracts from 34 Chinese herbal drugs, most of which are used for inflammatory diseases, were screened for their inhibitory effects on nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated J774.1 macrophages and in LPS/interferon (IFN)-γ-stimulated mouse peritoneal exudate macrophages. Among the extracts, methanol extracts of Myristica fragrans, Plantago asiatica, Rubia cordifolia, and Zanthoxylum bungeanum showed significant inhibition in J774.1 macrophages, ...
Tópico(s): Phytochemistry and Biological Activities
2001 - Elsevier BV | Journal of Ethnopharmacology
Suresh Awale, Suraj Prakash Shrestha, Yasuhiro Tezuka, Jun‐ya Ueda, Katsumichi Matsushige, Shigetoshi Kadota,
A methanolic extract of Nepalese propolis yielded 10 new open-chain neoflavonoids (1−10), a new chalcone (11), and eight previously reported compounds (12−19). Their structures were determined on the basis of spectroscopic data and chemical conversion. The isolated compounds other than 5, 8, and 16 showed dose-dependent inhibitory activities on nitric oxide production in lipopolysaccharide-activated macrophage-like J774.1 cells and were more active than a positive control, NG-monomethyl-l-arginine ( ...
Tópico(s): Essential Oils and Antimicrobial Activity
2005 - American Chemical Society | Journal of Natural Products
Jeevan K. Prasain, Yasuhiro Tezuka, Koji Hase, Purusotam Basnet, Hui Dong, Tsuneo NAMBA, Shigetoshi KADOTA,
Thirteen novel diarylheptanoids bearing a chalcone or a flavanone moiety (1-13), a new curcumin derivative, 1, 2-dihydrobis(de-O-methyl)curcumin(14), and two known flavonoids(15 and 16) isolated from the seeds of Alpinia blepharocalyx K. Schum. were tested for their inhibitory effects on nitric oxide (NO) production in lipopolysaccaride (LPS)-activated murine macrophages J774.1 in vitro. All the tested compounds inhibited NO production in a concentration-dependent manner (IC50=36-568 μM). Among the ...
Tópico(s): Phytochemistry and Biological Activities
1998 - Pharmaceutical Society of Japan | Biological and Pharmaceutical Bulletin
Hidetoshi Tezuka, Toshio Mori, Yasushi Okumura, Katsuaki Kitabatake, Yoshihiro Tsumura,
NHS5, a gene suppressing formation of hydrogen sulfide (H2S), was cloned from a Saccharomyces cerevisiae X2180-1A gene library. The gene was inserted into suitable vectors and introduced into bottom-fermentation yeasts. We verified that the strain with the inserted gene was effective in beer production because the gene reduced H2S content in green beer and did not affect other fermentation characters. We also proved that the function of the gene was related to production of cystathionine β-synthase.
Tópico(s): Fungal and yeast genetics research
1992 - Taylor & Francis | Journal of the American Society of Brewing Chemists
Takuya Kamino, Toshihiro Shimokura, Yusuke Morita, Yasuhiro Tezuka, Mikio Nishizawa, Ken Tanaka,
Tópico(s): Bioactive natural compounds
2016 - Springer Science+Business Media | Journal of Natural Medicines