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Imagens Acesso aberto

Photograph of the facade of the Do-Thal cave temple at Ellora from the 'Lee-Warner Collection: 'Bombay Presidency. William Lee Warner C.S.' taken by J. Johnston in the 1870s. ...

0000 - Gale Group | NCCO Photography

Artigo Revisado por pares

S. Pootrakul, Surang Assawamunkong, S Na-Nakorn,

... 1% A2-B-thalassemia genes: βO-thalassemia (βO-thal) or classical β-thalnssemia and β+-thalassemia (β+-thal) or mild 6-thalasseinin exist. This study presents ... synthesis in peripheral blood of the genuine β+-thal hetcrozygotes in comparision with those of the βO-thal heterozygotes. Thirty individuals of Thai and Chinese exctraction with the β+-thal heterozygosity were hematologically examined. The hematologic means of ... A2 and alkali3 denaturation hemoglobin of the β+-thal traits were, 11.7 g%, 67.8 u3, ...

Tópico(s): Blood groups and transfusion

1976 - Taylor & Francis | Hemoglobin

Imagens Acesso aberto

Photograph of the Tin Thal cave at Ellora from the 'Lee-Warner Collection: 'Bombay Presidency. William Lee Warner C.S.' taken by J. Johnston in ... between the sixth and the ninth Centuries. Tin-Thal is a Buddhist excavation that is thought to ...

0000 - Gale Group | NCCO Photography

Artigo Acesso aberto Revisado por pares

T. H. J. Huisman, ME Gravely, B. B. Webber, Kehinde O. Okonjo, J. B. Henson, A. L. Reese,

... of the A gamma T-chain in beta-thal heterozygotes and G gamma A gamma-HPFH heterozygotes ... detected in the nine G gamma-delta beta-thal heterozygotes nor in the eight G gamma-[delta+ ... A gamma gene in trans to the beta-thal or HPFH determinant. The contribution by the gamma-chain genes in trans to the beta-thal or HPFH determinant is about 15% of the ... production in both conditions. (C) Three black beta-thal heterozygotes (and five additional relatives) had the A gamma T gene in cis to the beta-thal determinant. Four of these patients had a low ...

Tópico(s): Blood groups and transfusion

1981 - Elsevier BV | Blood

Imagens Acesso aberto

... of the façade of the cave temple Tin Thal, Cave XII at Ellora in Maharashtra, from the ... dynasties between the 6th and 9th centuries. Tin Thal is a Buddhist excavation which probably dates from ...

0000 - Gale Group | NCCO Photography

Artigo Revisado por pares

Vivian Chan, T. K. Chan, D. Todd,

... because of the molecular heterogeneity of α-thalassemia (thal). The hallmark is the presence of excess β ... double heterozygosity for two deletional forms of α-thal, α-thal-1 and α-thal-2. The majority of cases with an α-thal-1 defect have a deletion of at least ... ζ-α gene cluster, i.e. ζ-α-thal-1. Of 33 α-thal-2 defects studied, 26 were the rightward deletion ( ... with Hb Q. About 10% of the α-thal defects belong to the nondeletion type, the most ... Spring (CS). This anomaly, when coinherited with α-thal-1, produces Hb H-CS disease which has ...

Tópico(s): Blood groups and transfusion

1988 - Taylor & Francis | Hemoglobin

Imagens Acesso aberto

... the façade of the cave temple XII, Tin-Thal, at Ellora in Maharashtra, from the right, taken ... dynasties between the 6th and 9th centuries. Tin Thal is a Buddhist excavation which probably dates from ...

0000 - Gale Group | NCCO Photography

Artigo Revisado por pares

Mathias Schmid, Maria Domenica Cappellini, John B. Porter, Peter L. Greenberg, Tomasz Lawniczek, Sabine Glaser, Victor Dong, Norbert Gattermann,

... MDS and non-MDS pts (β-thalassemia [β-thal] and other anemias [sickle cell, Diamond-Blackfan, aplastic ... mg/kg/day); 107 (randomized trial in β-thal pts, dosing 5–40 mg/kg/day) and ... data. Results 1798 pts were assessed (951 β-thal; 584 MDS, 263 other). MDS pts were older ( ... age 71 yrs) compared with those with β-thal (25 yrs) and other anemias (38 yrs). Mean actual dose of deferasirox (mg/kg/day): β-thal pts 23.5; MDS pts 20.3; other ... 34, 0.32 and 0.23 in β-thal, MDS and other anemias, respectively. At 1 yr, 88%, 53% and 69% of β-thal, MDS and other pts remained in the study, ...

Tópico(s): Myeloproliferative Neoplasms: Diagnosis and Treatment

2009 - Elsevier BV | Blood

Imagens Acesso aberto

Albumen Print of Hyp Thal Temple at Phyl. Fifty Years after This Photograph Was Taken the Egyptian Government Erected a Barrage across the River to ...

0000 - Gale Group | NCCO Photography

Revisão Revisado por pares

Rasik Gupta, R.S. Tiwary, P.L. Pande, F. Kutlar, C. Öner, R. Öner, T. H. J. Huisman,

... have investigated the frequencies and types of alpha-thal, beta-thal, and Hb variants among nearly 200 inhabitants of ... 85% were tribals of the Gond group. alpha-Thal, as -alpha 3.7/and -alpha 4.2/, ... the presence of other nondeletional types of alpha-thal. alpha-Globin gene triplications were not observed. Four of the six beta-thal alleles observed were in the tribal groups; two ( ... first time. The simultaneous presence of an alpha-thal (-alpha/alpha alpha or -alpha/-alpha) greatly improved ... condition of the patients with Hb S-beta(+)-thal (IVS-I-5; G----C). The lower frequency ...

Tópico(s): Iron Metabolism and Disorders

1991 - Taylor & Francis | Hemoglobin

Imagens Acesso aberto

Photograph of the tope (stupa) at Mir Rukan in Sind, Pakistan, taken by a photographer of the Archaeological survey of India in the 1870s. This Buddhist ...

0000 - Gale Group | NCCO Photography

Artigo Revisado por pares

Г. Д. Ефремов,

... that the average incidence of β-thalassemia (β-thal) trait is 1.2%, ranging from 2.9% ... in the northwest (Croatia). The frequency of δβ-thal is 0.2%, while the frequency of the ... newborns has shown that the frequency of α-thal trait is 1.6%. The molecular basis of the different forms of β-thal among Yugoslavians has been almost completely defined. Over 250 β-thal chromosomes have been studied, and in over 90% the molecular defect was determined. Eighteen different β-thal mutations have been detected, three of which (IVS- ...

Tópico(s): Neonatal Health and Biochemistry

1992 - Taylor & Francis | Hemoglobin

Artigo Acesso aberto Revisado por pares

Fabrizio Mastropietro, G. Modiano, Maria Pia Cappabianca, Enrica Foglietta, Carmelo D'asero, Mauro Mezzabotta, Donatella Ponzini, Laura Maffei, A. Amato, Margherita Lerone, Paola Grisanti, Paola Di Biagio, S. Rinaldi, I Bianco,

... of beta-thalassemia intermedia referred to as beta-thal int sub-silent and evident are associated with ... mutations of the beta-globin gene. Silent beta thal mutations are invariably associated with sub-silent beta thal int; beta° or severe beta+ thal mutations are associated with evident beta thal int (88%) and almost invariably (98%) with thalassemia ... in 26.9% of patients affected by beta-thal int sub-silent and evident, respectively, but only ... patients with thalassemia major. The severity of beta-thal int and the increased Hb F level are ...

Tópico(s): Blood groups and transfusion

2002 - Springer Science+Business Media | BMC Hematology

Musical work Acesso aberto

... 660. M Waldow: 'Von hoher Alp'zum stillen Thal. Gavotte'. [After 1861].'From lofty Alps to silent dale. Von hoher Alp'zum stillen Thal. Gavotte. op. 42'. Printed orchestral parts, published by ...

0000 - Gale Group | NCCO British Theatre

Artigo Acesso aberto Revisado por pares

Mohamad Mohty, Anne‐Marie Stoppa, Didier Blaise, Daniel Isnardon, Jean‐Albert Gastaut, Daniel Olive, Béatrice Gaugler,

Thalidomide (Thal) was shown to be a potent immunomodulating agent. Because of their central role in controlling immunity, we investigated the effects of Thal on monocyte-derived dendritic cells (Mo-DC). The ... micro g/ml or 20 micro g/ml Thal from the beginning of monocyte culture with granulocyte ... 4 did not block Mo-DC differentiation. Moreover, Thal alone could not induce Mo-DC maturation. However, Thal exerted a modulation of Mo-DC functional properties. At 10 micro g/ml, Thal modified the allostimulatory capacity of DC little, whereas ...

Tópico(s): vaccines and immunoinformatics approaches

2002 - Oxford University Press | Journal of Leukocyte Biology

Musical work Acesso aberto

... 660. M Waldow: 'Von hoher Alp'zum stillen Thal. Gavotte'. [After 1861].'From lofty Alps to silent dale. Von hoher Alp'zum stillen Thal. Gavotte. op. 42'. Printed orchestral parts, published by ...

0000 - Gale Group | NCCO British Theatre

Artigo Acesso aberto Revisado por pares

Pablo A. Ortiz, Jeffrey L. Garvin,

... thick ascending limb of the loop of Henle (THAL). The free radical superoxide (O 2 − ) reacts with ... oxidases, some of which are present in the THAL. However, the ability of the THAL to produce O 2 − and its interaction with ... that NO bioavailability is decreased by O 2 − . THALs were isolated and perfused and NO production was ... NO synthase inhibitor L-NAME (n=7). Scavenging THAL O 2 − with the superoxide dismutase (SOD) mimetic ... to the bath significantly increased NO release by THALs. Addition of SOD (300 U/mL) to the ...

Tópico(s): Electron Spin Resonance Studies

2002 - Lippincott Williams & Wilkins | Hypertension

Musical work Acesso aberto

... 660. M Waldow: 'Von hoher Alp'zum stillen Thal. Gavotte'. [After 1861].'From lofty Alps to silent dale. Von hoher Alp'zum stillen Thal. Gavotte. op. 42'. Printed orchestral parts, published by ...

0000 - Gale Group | NCCO British Theatre

Artigo Brasil Produção Nacional Revisado por pares

Aderson S. Araújo, Wilson A. Silva, Silvana A. Carneiro Leão, Flavia C. G. M. Bandeira, Mary Petrou, Bernadette Modell, Marco A. Zago,

... Brazil are sickle cell disease and beta-thalassemia (thal). The sickle gene was introduced by the slave trade, whereas beta-thal was introduced later, due to a massive immigration ( ... 47-54%), leading to severe forms of beta0-thal. However, the northeast region of the country has ... and since the majority of cases of beta-thal in Pernambuco, a state located in the northeast ... we would predict a different spectrum of beta-thal mutations in this region. We examined 60 unrelated patients (86 beta-thal chromosomes) under regular clinical follow-up in Pernambuco: ...

Tópico(s): Genomic variations and chromosomal abnormalities

2003 - Taylor & Francis | Hemoglobin

Musical work Acesso aberto

... 660. M Waldow: 'Von hoher Alp'zum stillen Thal. Gavotte'. [After 1861].'From lofty Alps to silent dale. Von hoher Alp'zum stillen Thal. Gavotte. op. 42'. Printed orchestral parts, published by ...

0000 - Gale Group | NCCO British Theatre

Artigo Acesso aberto Revisado por pares

Pablo A. Ortiz, Barbara A. Stoos, Nancy J. Hong, Dianne M. Boesch, Craig F. Plato, Jeffrey L. Garvin,

l -Arginine inhibits thick ascending limb (THAL) NaCl absorption by activating endothelial NO synthase (eNOS) and increasing NO production. Inhibition of renal NO production combined with a high-salt diet produces hypertension, and the THAL has been implicated in salt-sensitive hypertension. We ... action of l -arginine on NaCl absorption by THALs because of increased eNOS expression and NO production. To test this, we used isolated THALs from rats on a normal-salt (NS) or ... L) decreased chloride absorption by 56±10% in THALs from rats on a HS diet, but only ...

Tópico(s): Sodium Intake and Health

2003 - Lippincott Williams & Wilkins | Hypertension

Musical work Acesso aberto

... 660. M Waldow: 'Von hoher Alp'zum stillen Thal. Gavotte'. [After 1861].'From lofty Alps to silent dale. Von hoher Alp'zum stillen Thal. Gavotte. op. 42'. Printed orchestral parts, published by ...

0000 - Gale Group | NCCO British Theatre

Artigo Acesso aberto Revisado por pares

Pablo A. Ortiz, Nancy J. Hong, Ding Wang, Jeffrey L. Garvin,

... thick ascending limb of the loop of Henle (THAL) plays an essential role in the regulation of ... nitric oxide synthase (NOS), decreases NaCl absorption by THALs. We hypothesized that eNOS produces the NO that regulates THAL NaCl transport and that selective expression of eNOS in the THAL of eNOS knockout(−/−) mice would restore the effects ... was absent in Ad-NKCC2GFP–transduced kidneys. In THALs from eNOS−/− mice transduced with Ad-NKCC2eNOS, adding ... P <0.05; n=5), but not in THALs transduced with Ad-NKCC2GFP. In THALs from eNOS−/− ...

Tópico(s): Renin-Angiotensin System Studies

2003 - Lippincott Williams & Wilkins | Hypertension

Musical work Acesso aberto

... 660. M Waldow: 'Von hoher Alp'zum stillen Thal. Gavotte'. [After 1861].'From lofty Alps to silent dale. Von hoher Alp'zum stillen Thal. Gavotte. op. 42'. Printed orchestral parts, published by ...

0000 - Gale Group | NCCO British Theatre

Artigo Acesso aberto Revisado por pares

Pablo A. Ortiz, Nancy J. Hong, Craig F. Plato, Marisela Varela, Jeffrey L. Garvin,

... thick ascending limb of the loop of Henle (THAL) plays an important role in the maintenance of ... segments have been described, in vivo transduction of THALs has not been successful. We hypothesized that in ... renal medulla would result in efficient transduction of THALs.MethodsWe injected recombinant adenoviruses containing the reporter gene, ... K/2 Cl cotransporter (Ad-NKCC2GFP), which is THAL-specific, into the outer medullary interstitium of Sprague- ... the outer medulla (which is composed primarily of THALs) 5 days after Ad-CMVGFP injection. We quantified ...

Tópico(s): Metabolism and Genetic Disorders

2003 - Elsevier BV | Kidney International

Musical work Acesso aberto

... 660. M Waldow: 'Von hoher Alp'zum stillen Thal. Gavotte'. [After 1861].'From lofty Alps to silent dale. Von hoher Alp'zum stillen Thal. Gavotte. op. 42'. Printed orchestral parts, published by ...

0000 - Gale Group | NCCO British Theatre

Artigo Acesso aberto Revisado por pares

Gustavo Ares, Paulo S. Caceres, Francisco J. Alvarez‐Leefmans, Pablo A. Ortiz,

... thick ascending limb of the loop of Henle (THAL) is mediated by the apical Na/K/2Cl ... and natriuretic peptides, decrease NaCl absorption by the THAL. However, the mechanism by which cGMP decreases NaCl absorption in THALs is not known. We hypothesized that cGMP decreases surface NKCC2 levels in the THAL. We used surface biotinylation to measure surface NKCC2 levels in rat THAL suspensions. We tested the effect of the membrane- ... cGMP (db-cGMP) on surface NKCC2 levels. Incubating THALs with db-cGMP for 20 min decreased surface ...

Tópico(s): Ion Transport and Channel Regulation

2008 - American Physical Society | AJP Renal Physiology