FROM OUR RACING CORRESPONDENT., FROM OUR GOLF CORRESPONDENT., FROM OUR SPECIAL CORRESPONDENT., BY OUR COMMERCIAL MOTOR CORRESPONDENT., FROM OUR CHESS CORRESPONDENT., FROM OUR CIVIL SERVICE CORRESPONDENT., FROM OUR CORRESPONDENT., LATYMER., H. ARNOLD WOOLLEY, PERCY C. ATKINS., BLANCHE GORDON LENNOX., DOROTHY HAIG, PERCIVAL H. REED., J. C. F. HOOD., HUGH F. SPENDER., WALTER PAYNE., B. M. SKINNER., HENRY N. STEVENS, By CALLISTHENES., FROM OUR MUSIC CRITIC., FROM OUR CAIRO CORRESPONDENT., FROM OUR RIGA CORRESPONDENT., FROM OUR OWN CORRESPONDENT., FROM OUR OTTAWA CORRESPONDENT., From Our Parliamentary Correspondent., Our Winnipeg Correspondent, FROM OUR WEATHER CORRESPONDENT, H. JOHNSTONE MILLAR., DAVID C. LAMB, HAROLD MOXON, ALFRED D. FRIPP., FROM OUR CORRESPONDENT, FROM A CORRESPONDENT., Sir Evan Cotton, A correspondent, Mr. Paul Selver, FROM OUR TRADE CORRESPONDENT.,
... The Country. A Cistercian Abbey.. Obituaries: M. Otokar Brezina., Mr. R. M. Chellew., Mr. R. W. Reid., ...
1929 - Gale Group | TDA
Raymond M. Anchan, Behzad Gerami‐Naini, J. Suzanne Lindsey, Joshua W. K. Ho, Adam Kieżun, S.T. Lipskind, Nicholas Ng, Joseph A. LiCausi, Chloe S. Kim, Paul R. Brezina, Thomas Tuschl, Richard L. Maas, W.G. Kearns, Zev Williams,
To explore restoration of ovarian function using epigenetically-related, induced pluripotent stem cells (iPSCs), we functionally evaluated the epigenetic memory of novel iPSC lines, derived from mouse and human ovarian granulosa cells (GCs) using c-Myc, Klf4, Sox2 and Oct4 retroviral vectors. The stem cell identity of the mouse and human GC-derived iPSCs (mGriPSCs, hGriPSCs) was verified by demonstrating embryonic stem cell (ESC) antigen expression using immunocytochemistry and RT-PCR analysis, as well ...
Tópico(s): Reproductive Biology and Fertility
2015 - Public Library of Science | PLoS ONE
Marian Brezina, Thomas A. Manteuffel, S. MCormick, J. Ruge, Geoffrey Sanders,
Applying smoothed aggregation (SA) multigrid to solve a nonsymmetric linear system, $A\mathbf{x} =\mathbf{b}$, is often impeded by the lack of a minimization principle that can be used as a basis for the coarse-grid correction process. This paper proposes a Petrov–Galerkin (PG) approach based on applying SA to either of two symmetric positive definite (SPD) matrices, $\sqrt{A^{t}A}$ or $\sqrt{AA^{t}}$. These matrices, however, are typically full and difficult to compute, so it is not computationally efficient ...
Tópico(s): Sparse and Compressive Sensing Techniques
2010 - Society for Industrial and Applied Mathematics | SIAM Journal on Scientific Computing
Marian Brezina, Thomas A. Manteuffel, Steve McCormick, J. Ruge, Geoffrey Sanders, Panayot S. Vassilevski,
Abstract Consider the linear system A x = b , where A is a large, sparse, real, symmetric, and positive‐definite matrix and b is a known vector. Solving this system for unknown vector x using a smoothed aggregation (SA) multigrid algorithm requires a characterization of the algebraically smooth error, meaning error that is poorly attenuated by the algorithm's relaxation process. For many common relaxation processes, algebraically smooth error corresponds to the near‐nullspace of A . Therefore, having a ...
Tópico(s): Sparse and Compressive Sensing Techniques
2008 - Wiley | Numerical Linear Algebra with Applications
James H. Adler, Marian Brezina, Thomas A. Manteuffel, Steve McCormick, J. Ruge, Lei Tang,
This paper investigates the performance of a parallel Newton, first-order system least-squares (FOSLS) finite-element method with local adaptive refinement and algebraic multigrid (AMG) applied to incompressible, resistive magnetohydrodynamics. In particular, an island coalescence test problem is studied that models magnetic reconnection using a reduced two-dimensional (2D) model of a tokamak fusion reactor. The results show that, using an appropriate temporal and spatial resolution, these methods ...
Tópico(s): Magnetic confinement fusion research
2013 - Society for Industrial and Applied Mathematics | SIAM Journal on Scientific Computing
J. Brannick, Marian Brezina, Scott MacLachlan, Thomas A. Manteuffel, Steve McCormick, J. Ruge,
Abstract Algebraic multigrid (AMG) is an iterative method that is often optimal for solving the matrix equations that arise in a wide variety of applications, including discretized partial differential equations. It automatically constructs a sequence of increasingly smaller matrix problems that hopefully enables efficient resolution of all scales present in the solution. The methodology is based on measuring how a so‐called algebraically smooth error value at one point depends on its value at another. ...
Tópico(s): Matrix Theory and Algorithms
2006 - Wiley | Numerical Linear Algebra with Applications
Bruno Walser, Paul R. Brezina, Thomas Geiger,
Der Einfluß langzeitigen Anlassens auf das Gefüge, die Härte und die Zeitstandeigenschaften von X 22 CrMoV 12 1 wird dargestellt. Thermisch bedingte Gefügeänderungen führen zu einem Härteabfall und können die Beanspruchungsdauer bis zum Bruch gegenüber dem Ausgangszustand bis 70 % vermindern. Die normierte Darstellung der Versuchsdaten ergibt ein Hilfsmittel zur Abschätzung der allein durch Zeit und Temperatur bedingten Lebensdauerverminderung.
Tópico(s): Hydrogen embrittlement and corrosion behaviors in metals
1979 - Wiley | Archiv für das Eisenhüttenwesen
Marian Brezina, C. Ketelsen, Thomas A. Manteuffel, Stephen F. McCormick, M. Park, J. Ruge,
SUMMARY Bootstrap algebraic multigrid (BAMG) is a multigrid‐based solver for matrix equations of the form Ax = b . Its aim is to automatically determine the interpolation weights used in algebraic multigrid by locally fitting a set of test vectors that have been relaxed as solutions to the corresponding homogeneous equation, Ax = 0. This paper studies an improved form of BAMG, called relaxation‐corrected bootstrap algebraic multigrid ( r BAMG), that involves adding scaled residuals of the test vectors to ...
Tópico(s): Tensor decomposition and applications
2012 - Wiley | Numerical Linear Algebra with Applications
Cornelia Zöchmeister, Stefanie Brezina, Philipp Hofer, Andreas Baierl, Michael Bergmann, Thomas Bachleitner‐Hofmann, Judith Karner‐Hanusch, Anton Stift, Armin Gerger, Gernot Leeb, Karl Mach, P. Sivaramakrishna Rachakonda, Rajiv Kumar, Andrea Gsur,
// Cornelia Zöchmeister 1, * , Stefanie Brezina 1, * , Philipp Hofer 1 , Andreas Baierl 2 , Michael M. Bergmann 3 , Thomas Bachleitner-Hofmann 3 , Judith Karner-Hanusch 3 , Anton Stift 3 , Armin Gerger 4 , Gernot Leeb 5 , Karl Mach 5 , Sivaramakrishna ...
Tópico(s): Cancer Cells and Metastasis
2018 - Impact Journals LLC | Oncotarget
Anne J. M. R. Geijsen, Stefanie Brezina, Pekka Keski‐Rahkonen, Andreas Baierl, Thomas Bachleitner‐Hofmann, Michael Bergmann, Juergen Boehm, Hermann Brenner, Jenny Chang‐Claude, Fränzel J.B. van Duijnhoven, Biljana Gigic, Tanja Gumpenberger, Philipp Hofer, Michael Hoffmeister, Andreana N. Holowatyj, Judith Karner‐Hanusch, Dieuwertje E. Kok, Gernot Leeb, Arve Ulvik, Nivonirina Robinot, Jennifer Ose, Anton Stift, Petra Schrotz‐King, Alexis Ulrich, Per Magne Ueland, Ellen Kampman, Augustin Scalbert, James E. Haber, Andrea Gsur, Cornelia M. Ulrich,
Colorectal cancer is known to arise from multiple tumorigenic pathways; however, the underlying mechanisms remain not completely understood. Metabolomics is becoming an increasingly popular tool in assessing biological processes. Previous metabolomics research focusing on colorectal cancer is limited by sample size and did not replicate findings in independent study populations to verify robustness of reported findings. Here, we performed a ultrahigh performance liquid chromatography‐quadrupole ...
Tópico(s): Cancer, Lipids, and Metabolism
2019 - Wiley | International Journal of Cancer
Marian Brezina, Robert D. Falgout, Scott MacLachlan, Thomas A. Manteuffel, Stephen F. McCormick, J. Ruge,
Efficient numerical simulation of physical processes is constrained by our ability to solve the resulting linear systems, prompting substantial research into the development of multiscale iterative methods capable of solving these linear systems with an optimal amount of effort. Overcoming the limitations of geometric multigrid methods to simple geometries and differential equations, algebraic multigrid methods construct the multigrid hierarchy based only on the given matrix. While this allows for ...
Tópico(s): Matrix Theory and Algorithms
2006 - Society for Industrial and Applied Mathematics | SIAM Journal on Scientific Computing
Marian Brezina, Robert D. Falgout, Scott MacLachlan, Thomas A. Manteuffel, Steve McCormick, J. Ruge,
Substantial effort has been focused over the last two decades on developing multilevel iterative methods capable of solving the large linear systems encountered in engineering practice. These systems often arise from discretizing partial differential equations over unstructured meshes, and the particular parameters or geometry of the physical problem being discretized may be unavailable to the solver. Algebraic multigrid (AMG) and multilevel domain decomposition methods of algebraic type have been ...
Tópico(s): Numerical methods for differential equations
2005 - Society for Industrial and Applied Mathematics | SIAM Review
Marian Brezina, Robert D. Falgout, Scott MacLachlan, Thomas A. Manteuffel, Steve McCormick, J. Ruge,
Substantial effort has been focused over the last two decades on developing multilevel iterative methods capable of solving the large linear systems encountered in engineering practice. These systems often arise from discretizing partial differential equations over unstructured meshes, and the particular parameters or geometry of the physical problem being discretized may be unavailable to the solver. Algebraic multigrid (AMG) and multilevel domain decomposition methods of algebraic type have been ...
Tópico(s): Numerical methods for differential equations
2004 - Society for Industrial and Applied Mathematics | SIAM Journal on Scientific Computing
Marian Brezina, José María García, Thomas A. Manteuffel, Stephen F. McCormick, J. Ruge, Liang Tang,
SUMMARY This paper develops new adaptive mesh refinement strategies for first‐order system least squares (FOSLS) in conjunction with algebraic multigrid (AMG) methods in the context of nested iteration (NI). The goal is to reach a certain error tolerance with the least amount of computational cost and nearly uniform distribution of the error over all elements. To accomplish this, the refinement decisions at each refinement level are determined on the basis of minimizing the ‘accuracy‐per‐computational‐ ...
Tópico(s): Matrix Theory and Algorithms
2012 - Wiley | Numerical Linear Algebra with Applications
Elena Brezina, Carsten Prasse, Manfred Wagner, Thomas A. Ternes,
Carbamazepine (CBZ) is a worldwide used antiepileptic drug, which is metabolized to a large extent in the human body to several metabolites, including 10,11-dihydroxy-10,11-dihydrocarbamazepine (DiOHCBZ), 2-hydroxycarbamazepine (2OHCBZ), and 3-hydroxycarbamazepine (3OHCBZ). 2OHCBZ and 3OHCBZ were previously detected in raw and treated wastewater revealing their widespread emission into the aquatic environment, eventually leading to the contamination of drinking water resources. Sand filtration is frequently ...
Tópico(s): Water Treatment and Disinfection
2015 - American Chemical Society | Environmental Science & Technology
James Brannick, Marian Brezina, Robert D. Falgout, Thomas A. Manteuffel, Steve McCormick, J. Ruge, Brendan Sheehan, Jinchao Xu, Ludmil Zikatanov,
Multigrid methods are ideal for solving the increasingly large-scale problems that arise in numerical simulations of physical phenomena because of their potential for computational costs and memory requirements that scale linearly with the degrees of freedom. Unfortunately, they have been historically limited by their applicability to elliptic-type problems and the need for special handling in their implementation. In this paper, we present an overview of several recent theoretical and algorithmic ...
Tópico(s): Computational Fluid Dynamics and Aerodynamics
2006 - IOP Publishing | Journal of Physics Conference Series
Elena Brezina, Carsten Prasse, Johannes Meyer, Harald Mückter, Thomas A. Ternes,
Trace organic contaminants such as pharmaceuticals, personal care products and industrial chemicals are frequently detected in the urban water cycle, including wastewater, surface water and groundwater, as well as drinking water. These also include human metabolites (HMs), which are formed in the human body and then excreted via urine or feces, as well as transformation products (TPs) formed in engineered treatment systems and the aquatic environment. In the current study, the occurrence of HMs as ...
Tópico(s): Water Treatment and Disinfection
2017 - Elsevier BV | Environmental Pollution
Stephen G. Ellis, Marc S. Penn, Brian J. Bolwell, Mario J. García, Matthews Chacko, Thomas J. Wang, Kelly J. Brezina, Gerry McConnell, Eric J. Topol,
Preclinical studies suggest that administration of cytokines to mobilize stem cells and alter the postinfarction inflammatory cardiac milieu may enhance left ventricular function and survival. Eighteen patients were randomized in a 2:1 double-blind fashion to granulocyte colony stimulating factor (G-CSF) (at 5 escalating to 10 μg/kg per day subcutaneously for 5 days [6 patients in each group]) or matching placebo. Principal safety and efficacy end points were rupture-free survival and recovery of left ...
Tópico(s): Cardiac Fibrosis and Remodeling
2006 - Elsevier BV | American Heart Journal
2016 - J.B. Metzler | Zeitschrift für Literaturwissenschaft und Linguistik
Das Stipendium wird dem Wirken von Herrn Prim. Prof. Dr. K. Brezina gerecht, dessen Lebenswerk sich schwerpunktmäßig mit der Ausbildung von RadiologInnen beschäftigte und der auch den "Kotscher-Fortbildungskurs" institutionalisierte.
Tópico(s): Historical, Literary, and Cultural Studies
2008 - Thieme Medical Publishers (Germany) | RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
Das Stipendium wird dem Wirken von Herrn Prim. Prof. Dr. K. Brezina gerecht, dessen Lebenswerk sich schwerpunktmäßig mit der Ausbildung von RadiologInnen beschäftigte und der auch den "Kotscher-Fortbildungskurs" institutionalisierte.
Tópico(s): Medical Practices and Rehabilitation
2007 - Thieme Medical Publishers (Germany) | RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
Travis Austin, Marian Brezina, Ben Jamroz, Chetan Jhurani, Thomas A. Manteuffel, J. Ruge,
High-order finite elements often have a higher accuracy per degree of freedom than the classical low-order finite elements. However, in the context of implicit time-stepping methods, high-order finite elements present challenges to the construction of efficient simulations due to the high cost of inverting the denser finite element matrix. There are many cases where simulations are limited by the memory required to store the matrix and/or the algorithmic components of the linear solver. We are particularly ...
Tópico(s): Electromagnetic Simulation and Numerical Methods
2012 - Elsevier BV | Journal of Computational Physics
Marian Brezina, Andrew Cleary, Robert D. Falgout, Van Emden Henson, Jim E. Jones, Thomas A. Manteuffel, Steve McCormick, J. Ruge,
We introduce AMGe, an algebraic multigrid method for solving the discrete equations that arise in Ritz-type finite element methods for partial differential equations. Assuming access to the element stiffness matrices, we have that AMGe is based on the use of two local measures, which are derived from global measures that appear in existing multigrid theory. These new measures are used to determine local representations of algebraically "smooth" error components that provide the basis for constructing ...
Tópico(s): Electromagnetic Simulation and Numerical Methods
2001 - Society for Industrial and Applied Mathematics | SIAM Journal on Scientific Computing
Philipp Hofer, Michael Hagmann, Stefanie Brezina, Erich Dolejsi, Karl Mach, Gernot Leeb, Andreas Baierl, Stephan Buch, Hedwig Sutterlüty, Judith Karner‐Hanusch, Michael Bergmann, Thomas Bachleitner‐Hofmann, Anton Stift, Armin Gerger, Katharina Rötzer, J. Karner, Stefan Stättner, Mélanie Waldenberger, Thomas Meitinger, Konstantin Strauch, Jakob Linseisen, Christian Gieger, Florian Frommlet, Andrea Gsur,
Most genome-wide association studies (GWAS) were analyzed using single marker tests in combination with stringent correction procedures for multiple testing. Thus, a substantial proportion of associated single nucleotide polymorphisms (SNPs) remained undetected and may account for missing heritability in complex traits. Model selection procedures present a powerful alternative to identify associated SNPs in high-dimensional settings. In this GWAS including 1060 colorectal cancer cases, 689 cases of ...
Tópico(s): Colorectal Cancer Screening and Detection
2017 - Impact Journals LLC | Oncotarget
... Firing Patterns and Muscle Contraction in Rhythmic BehaviorsVladimir Brezina, Irina V. Orekhova, and Klaudiusz R. Weiss1 January 2000 | Journal of Neurophysiology, Vol. 83, No. 1Pattern of Pulses That Maximize Force Output From Single Human Thenar Motor UnitsC. K. Thomas, R. S. Johansson, and B. Bigland-Ritchie1 December ...
Tópico(s): Motor Control and Adaptation
1980 - American Physiological Society | Journal of Neurophysiology
Albert C. Yeh, Mohiuddin Ahmed Khan, Jason Harlow, Akhil Ranjan Biswas, Mafruha Akter, Jannatul Ferdous, Tasneem Ara, Manirul Islam, Martin Caron, Anne‐Marie Barron, Jenna A. Moran, Mark Brezina, Humayra Nazneen, M Kamruzzaman, Anup Kumar Saha, Ariela L. Marshall, Salma Afrose, Christopher P. Stowell, Frederic I. Preffer, David R. Bangsberg, Annekathryn Goodman, Eyal C. Attar, Steven L. McAfee, Thomas R. Spitzer, Bimalangshu R. Dey,
Treatment of malignant and nonmalignant hematologic diseases with hematopoietic stem-cell transplantation (HSCT) was first described almost 60 years ago, and its use has expanded significantly over the last 20 years. Whereas HSCT has become the standard of care for many patients in developed countries, the significant economic investment, infrastructure, and health care provider training that are required to provide such a service have prohibited it from being widely adopted, particularly in developing ...
Tópico(s): Acute Lymphoblastic Leukemia research
2017 - American Society of Clinical Oncology | Journal of Global Oncology
Yi‐Bin Chen, Tracy T. Batchelor, Shuli Li, Ephraim P. Hochberg, Mark Brezina, SooAe Jones, Candice Del Rio, Morgan Curtis, Karen K. Ballen, Jeffrey A. Barnes, S. Andrew, Jörg Dietrich, Jessica Driscoll, Elizabeth R. Gertsner, Fred H. Hochberg, Ann S. LaCasce, Steven L. McAfee, Thomas R. Spitzer, Lakshmi Nayak, Philippe Armand,
BACKGROUND High‐dose thiotepa, busulfan, and cyclophosphamide (TBC) with autologous stem cell transplantation (ASCT) has been used in patients with central nervous system (CNS) involvement by non‐Hodgkin lymphoma (NHL). Despite limited penetration into the CNS, rituximab is active in primary CNS NHL. Therefore, high‐dose rituximab was combined with TBC for ASCT in patients with CNS NHL. METHODS A single‐arm phase 2 trial using high‐dose rituximab with cytarabine for stem cell mobilization followed by ...
Tópico(s): Lymphoma Diagnosis and Treatment
2014 - Wiley | Cancer
Anne J. M. R. Geijsen, Arve Ulvik, Biljana Gigic, Dieuwertje E. Kok, Fränzel J.B. van Duijnhoven, Andreana N. Holowatyj, Stefanie Brezina, Eline H. van Roekel, Andreas Baierl, Michael Bergmann, Jürgen Böhm, Martijn J.L. Bours, Hermann Brenner, Stéphanie O. Breukink, Mary P. Bronner, Jenny Chang‐Claude, Johannes H.W. de Wilt, William M. Grady, Thomas Grünberger, Tanja Gumpenberger, Esther Herpel, Michael Hoffmeister, Lyen C. Huang, Jolanta Jedrzkiewicz, Eric T.P. Keulen, Rama Kiblawi, Torsten Kölsch, Janna L. Koole, Katharina Kosma, Ewout A. Kouwenhoven, Flip M. Kruyt, Gry Kvalheim, Christopher I. Li, Tengda Lin, Jennifer Ose, T. Bartley Pickron, Courtney L. Scaife, Peter Schirmacher, Martin Schneider, Petra Schrotz‐King, Marie C Singer, Eric R. Swanson, Peter van Duijvendijk, Henk K. van Halteren, Moniek van Zutphen, Kathy Vickers, F. Jeroen Vogelaar, Evertine Wesselink, James E. Haber, Alexis Ulrich, Per Magne Ueland, Matty P. Weijenberg, Andrea Gsur, Cornelia M. Ulrich, Ellen Kampman,
Folates, including folic acid, may play a dual role in colorectal cancer development. Folate is suggested to be protective in early carcinogenesis but could accelerate growth of premalignant lesions or micrometastases. Whether circulating concentrations of folate and folic acid, measured around time of diagnosis, are associated with recurrence and survival in colorectal cancer patients is largely unknown.
Tópico(s): Nutrition and Health in Aging
2020 - Oxford University Press | JNCI Cancer Spectrum
T. Brezina, H. Dewitz, Thomas Schroeder, Stephen E. Ullrich, Kathrin Nachtkamp, Guido Reifenberger, Bastian Malzkorn, Michael Sabel, Rainer Haas, Guido Kobbe,
Abstract Primary central nervous system non-Hodgkin lymphomas (PCNS-NHLs) are extranodal B-cell lymphomas with poor prognosis. The role of high-dose therapy (HDT) followed by autologous blood stem cell transplantation (ASCT) as first-line therapy is still not clear. We retrospectively collected long-term follow up data of 61 consecutive patients with PCNS-NHL at the University Hospital Düsseldorf from January 2004 to December 2016. Thirty-six patients were treated with conventional chemoimmunotherapy ( ...
Tópico(s): Glioma Diagnosis and Treatment
2022 - Springer Science+Business Media | Annals of Hematology
Robert D. Falgout, James Brannick, Marian Brezina, Thomas A. Manteuffel, Steve McCormick,
In this paper, we highlight new multigrid solver advances in the Terascale Optimal PDE Simulations (TOPS) project in the Scientific Discovery Through Advanced Computing (SciDAC) program. We discuss two new algebraic multigrid (AMG) developments in TOPS: the adaptive smoothed aggregation method (αSA) and a coarse-grid selection algorithm based on compatible relaxation (CR). The αSA method is showing promising results in initial studies for Quantum Chromodynamics (QCD) applications. The CR method has the ...
Tópico(s): Advanced Numerical Methods in Computational Mathematics
2005 - IOP Publishing | Journal of Physics Conference Series