Jos. Adolphus, Abner Thorp, E. H. Coovert, A. Jackson Howe, Dr. A. D. Bundy, A. Jackson Howe, Dr. Thomas Inman, Dr. W. H. Broadbent, William S. Savory, Dr. B. W. Richardson, Arthur Leared, Dr. Duncan Menzies, Mr. J. C. Skey, M. Demarquay, J. E. Petrequin, I. G. M. Goss, J. W. Smith, Thomas King Chambers, William Acton, John M. Scudder, I. A. Thayer,
... Especially in Those of the Eye, Tooth Cement (Stehle), Varieties, The Cure ... On Catching Cold. By Dr. Thomas Inman, A Case in Surgery. By Abner Thorp, ...
1867 - Gale Group | NCCO-STM 1of2
Ulrich E. Schaible, Reinhard Wallich, Michael D. Kramer, Gabi Nerz, Thomas Stehle, C Muşeţeanu, Markus M. Simon,
... author on: Oxford Academic PubMed Google Scholar Thomas Stehle, Thomas Stehle Search for other works by this author on: ...
Tópico(s): T-cell and B-cell Immunology
1994 - Oxford University Press | International Immunology
Dr. John Southey Warter, Dr. Thomas Armetirding Compton, Dr. Thomas A. Compton, Dr. Sydney Ringer, W. B. Kesteven, F. C. Skey, Dr. Thomas Inman, Dr. J. Birkbeck Nevins, Dr. W. H. Broadbent, Dr. Samuel Wilks, F. C. Skey, Dr. Francis E. Anstie, Dr. Edward Long Fox, Dr. William Leishman, Dr. Francis Delafield, Dr. J. Henry Bennet, Dr. Hyde Salter, Dr. Hyde Salter, Dr. W. Newman, Dr. F. W. Pavy, Dr. F. W. Pavy, Dr. G. Owen Rees, Dr. F. W. Pavy, Dr. Arthur Hill Hassall, Dr. F. W. Pavy, Henry Hancock, Dr. Robert M'Donnell, Thomas Nunneley, Dr. G. Hamilton, Richard Barwell, William S. Savory, Dr. W. A. Wetherby, Dr. Julian J. Chisolm, Arthur E. Durham, Dr. Maurice H. Collis, Dr. J. Y. Totherick, Dr. T. Parvin, Dr. Andrew Paul, John Adams, Christopher Heath, Dr. Charles Owen Aspray, Henry Thompson, John Hilton, Edward Cock, T. Pridgin Teale Jr., John Wood, Dr. T. W. Belcher, F. C. Skey, J. Z. Laurence, James Rouse, Dr. J. S. Prettyman, Dr. H. Samuel Perdon, Dr. Lumley Earle, Robert Ellis, Dr. C. B. Suckling, Dr. Thomas Dalton, William S. Savory, T. Spencer Wells, I. B. Brown, Dr. R. T. Tracy, Dr. C. H. F. Routh, Dr. C. B. Garrett, W. Whalley, Dr. Charles Kidd, Dr. James F. Duncan, Francis McLean, Harry Lobb, Dr. Henry S. Downs, Dr. Joseph Buller, Dr. B. W. Richardson, Henry Lee, Dr. H. Bence Jones, Dr. W. H. Broadbent, Dr. James F. Duncan, Dr. Hyde Salter, Dr. Alex. Robertson, Dr. Robert Greenhalgh, Dr. W. H. Broadbent, Dr. F. E. Junker, Dr. W. H. Broadbent, Dr. J. Hughes Bennett, Dr. Julius Althaus, Dr. F. P. Atkinson, F. A. Bulley, Dr. G. E. Nicholas,
... the Medical Uses of Chloroform Inhalation, Tooth Cement (Stehle), Physiological Action of Narceine, On a New Method ...
1867 - Gale Group | NCCO-STM 1of2
Thomas Stehlé, Pierre Delanaye,
Abstract Background The glomerular filtration rate (GFR) is estimated by the serum or plasma concentration of creatinine and/or cystatin C using equations that include demographic data. The equations worldwide most widely used are those of the Chronic Kidney Disease Epidemiology Collaboration (CKD‐EPI) consortium and updated in 2021 to remove the Afro‐American racial correction factor. In 2021 and then in 2023, the European Kidney Function Consortium also developed equations based on creatinine and ...
Tópico(s): Renal Diseases and Glomerulopathies
2024 - Wiley | European Journal of Clinical Investigation
Christoph Mamot, Reto Ritschard, Andreas Wicki, Gregor Stehle, Thomas Dieterle, Lukas Bubendorf, Christoph Hilker, Stefanie Deuster, Richard Herrmann, Christoph Rochlitz,
Background Results of preclinical studies have shown that EGFR immunoliposomes have substantial antitumour effects. We aimed to assess the tolerability, safety, pharmokinetics, and efficacy of anti-EGFR immunoliposomes loaded with doxorubicin (anti-EGFR ILs-dox) in patients with solid tumours. Methods In this first-in-man, open-label, phase 1 clinical study, we enrolled patients at University Hospital of Basel, Switzerland, who had EGFR-overexpressing advanced solid tumours no longer amenable to ...
Tópico(s): Lung Cancer Research Studies
2012 - Elsevier BV | The Lancet Oncology
Sven Wehner, Katharina Meder, Tim O. Vilz, Birgit Alteheld, Peter Stehle, Thomas Pech, Joerg C. Kalff,
Tópico(s): Clinical Nutrition and Gastroenterology
2011 - Springer Science+Business Media | Langenbeck s Archives of Surgery
Stefan Wellert, Brigtte Tiersch, Joachim Koetz, André Richardt, Alain Lapp, Olaf Holderer, Jürgen Gäb, Marc‐Michael Blum, Christoph Schulreich, Ralf Stehle, Thomas Hellweg,
Tópico(s): Surfactants and Colloidal Systems
2011 - Springer Science+Business Media | European Biophysics Journal
Andreas Wunder, Ulf Müller–Ladner, Ernst H. K. Stelzer, Jürgen Funk, Elena Neumann, G. Stehle, Thomas Pap, Hannsjörg Sinn, Steffen Gay, Christoph Fiehn,
We reported recently that albumin is a suitable drug carrier for targeted delivery of methotrexate (MTX) to tumors. Due to pathophysiological conditions in neoplastic tissue, high amounts of albumin accumulate in tumors and are metabolized by malignant cells. MTX, covalently coupled to human serum albumin (MTX-HSA) for cancer treatment, is currently being evaluated in phase II clinical trials. Because synovium of patients with rheumatoid arthritis (RA) shares various features observed also in tumors, ...
Tópico(s): Chronic Myeloid Leukemia Treatments
2003 - American Association of Immunologists | The Journal of Immunology
Fee Stehle, Thomas Hickmann, Markus Lederer, Chris Höhne,
Several scholars have pointed to the increasing salience of cities in the global endeavour to reduce dangerous climate change to 1.5°C. However, we still lack systematic comparative analyses on how urban climate initiatives evolve in different political-administrative systems of countries in the global South and what role transnational city networks play in that context. This question is specifically important with regard to the role of cities in contributing to reaching the targets of the Paris ...
Tópico(s): Climate Change Policy and Economics
2020 - SAGE Publishing | Urbanisation
F. Pigneur, Alain Luciani, Mario Ghosn, Édouard Reizine, Antoine Morel, Thomas Stehlé,
... Alain Luciani*, Mario Ghosn*, Edouard Reizine*, Antoine Morel†, Thomas Stehlé†Frédéric Pigneur* , Alain Luciani*, Mario Ghosn*, Edouard Reizine*, Antoine Morel†, Thomas Stehlé†Author AffiliationsDepartment of Medical Imaging, Henri Mondor Hospital, ... Alain Luciani*Mario Ghosn*Edouard Reizine*Antoine Morel†Thomas Stehlé†Published Online:May 9 2023https://doi.org/10. ...
Tópico(s): Liver Disease and Transplantation
2023 - Radiological Society of North America | Radiology
Dina Becker, Steffen Boley, Rocco Eisseler, Thomas Stehle, Hans‐Christian Möhring, Volkher Onuseit, Max Hoßfeld, Thomas Graf,
Abstract This paper describes the interdependence of additive and subtractive manufacturing processes using the production of test components made from S Al 5356. To achieve the best possible part accuracy and a preferably small wall thickness already within the additive process, a closed loop process control was developed and applied. Subsequent machining processes were nonetheless required to give the components their final shape, but the amount of material in need of removal was minimised. The ...
Tópico(s): Additive Manufacturing and 3D Printing Technologies
2021 - Springer Science+Business Media | Production Engineering
Bilal N. Sheikh, Wibke Bechtel‐Walz, Jacopo Lucci, O Karpiuk, I Hild, B. Hartleben, Julia Vornweg, Martin Helmstädter, Abdullah H. Sahyoun, Vivek Bhardwaj, Thomas Stehlé, Sean A. Diehl, Oliver Kretz, Anne K. Voss, Tim Thomas, Thomas Manke, Tobias B. Huber, Asifa Akhtar,
MOF (MYST1, KAT8) is the major H4K16 lysine acetyltransferase (KAT) in Drosophila and mammals and is essential for embryonic development. However, little is known regarding the role of MOF in specific cell lineages. Here we analyze the differential role of MOF in proliferating and terminally differentiated tissues at steady state and under stress conditions. In proliferating cells, MOF directly binds and maintains the expression of genes required for cell cycle progression. In contrast, MOF is dispensable ...
Tópico(s): Renal and related cancers
2015 - Springer Nature | Oncogene
Aindrila Chatterjee, Janine Seyfferth, Jacopo Lucci, Ralf Gilsbach, Sebastian Preißl, Lena Böttinger, Christoph U. Mårtensson, Amol Panhale, Thomas Stehlé, Oliver Kretz, Abdullah H. Sahyoun, Sergiy Avilov, Stefan Eimer, Lutz Hein, Nikolaus Pfanner, Thomas Becker, Asifa Akhtar,
A functional crosstalk between epigenetic regulators and metabolic control could provide a mechanism to adapt cellular responses to environmental cues. We report that the well-known nuclear MYST family acetyl transferase MOF and a subset of its non-specific lethal complex partners reside in mitochondria. MOF regulates oxidative phosphorylation by controlling expression of respiratory genes from both nuclear and mtDNA in aerobically respiring cells. MOF binds mtDNA, and this binding is dependent ...
Tópico(s): RNA modifications and cancer
2016 - Cell Press | Cell
Bilal N. Sheikh, Sukanya Guhathakurta, Tsz Hong Tsang, Marius Schwabenland, Gina Renschler, Benjamin Herquel, Vivek Bhardwaj, Herbert Holz, Thomas Stehlé, Olga Bondareva, Nadim Aizarani, Omar Mossad, Oliver Kretz, Wilfried Reichardt, Aindrila Chatterjee, Laura J. Braun, Julien Thévenon, Hervé Sartelet, Thomas Blank, Dominic Grün, Dominik von Elverfeldt, Tobias B. Huber, Dietmar Vestweber, Sergiy Avilov, Marco Prinz, Joerg M. Buescher, Asifa Akhtar,
Tópico(s): NF-κB Signaling Pathways
2020 - Nature Portfolio | Nature Cell Biology
Lyubomir Zagorchev, Carsten Meyer, Thomas Stehlé, Fabian Wenzel, Stewart Young, Jörg Peters, Juergen Weese, Keith D. Paulsen, Matthew Garlinghouse, James Ford, Robert M. Roth, Laura A. Flashman, Thomas W. McAllister,
Conventional structural imaging is often normal after mild traumatic brain injury (mTBI). There is a need for structural neuroimaging biomarkers that facilitate detection of milder injuries, allow recovery trajectory monitoring, and identify those at risk for poor functional outcome and disability. We present a novel approach to quantifying volumes of candidate brain regions at risk for injury. Compared to controls, patients with mTBI had significantly smaller volumes in several regions including ...
Tópico(s): Cardiac Arrest and Resuscitation
2015 - Mary Ann Liebert, Inc. | Journal of Neurotrauma
Pierre Delanaye, Étienne Cavalier, Hans Pottel, Thomas Stehlé,
Glomerular filtration rate (GFR) is estimated in clinical practice from equations based on the serum concentration of endogenous biomarkers and demographic data. The 2009 creatinine-based Chronic Kidney Disease Epidemiology Collaboration equation (CKD-EPI
Tópico(s): Renal Diseases and Glomerulopathies
2023 - Oxford University Press | Clinical Kidney Journal
Produção Nacional
Revisado por pares
Pierre Delanaye, Emmanuelle Vidal‐Petiot, Jonas Björk, Natalie Ebert, Bjørn O. Eriksen, Laurence Dubourg, Anders Grubb, Magnus Hansson, Karin Littmann, Christophe Mariat, Toralf Melsom, Elke Schäeffner, Per‐Ola Sundin, Arend Bökenkamp, Ulla Berg, Kajsa Åsling‐Monemi, Anna Åkesson, Anders Larsson, Étienne Cavalier, R. Neil Dalton, Marie Courbebaisse, Lionel Couzi, F. Gaillard, Cyril Garrouste, Lola Jacquemont, Nassim Kamar, Christophe Legendre, Lionel Rostaing, Thomas Stehlé, Jean‐Philippe Haymann, Luciano da Silva Selistre, Jorge Paulo Strogoff de Matos, Justine Busanga Bukabau, Ernest Kiswaya Sumaili, Eric Yayo, Dagui Monnet, Ulf Nyman, Hans Pottel, Martin Flamant,
A new Chronic Kidney Disease Epidemiology Collaboration equation without the race variable has been recently proposed (CKD-EPIAS). This equation has neither been validated outside USA nor compared with the new European Kidney Function Consortium (EKFC) and Lund-Malmö Revised (LMREV) equations, developed in European cohorts.Standardized creatinine and measured glomerular filtration rate (GFR) from the European EKFC cohorts (n = 13 856 including 6031 individuals in the external validation cohort), from France ( ...
Tópico(s): Renal Diseases and Glomerulopathies
2022 - Oxford University Press | Nephrology Dialysis Transplantation
Michael Storchak, K. Drewle, Christian Menze, Thomas Stehle, Hans‐Christian Möhring,
The thermomechanical interaction of the tool with the chip in the most loaded secondary cutting zone depends on the contact length of the tool rake face with the chip. Experimental studies of the dependency of the contact length on the cutting speed, the undeformed chip thickness, and the tool rake angle, performed by the optical method, are used for comparison with the contact length obtained by the FE modeling of the orthogonal cutting process. To determine the parameters of the constitutive Johnson- ...
Tópico(s): Advanced Surface Polishing Techniques
2022 - Multidisciplinary Digital Publishing Institute | Materials
Cecília Pessoa Rodrigues, Josip S. Herman, Benjamin Herquel, Claudia Isabelle Keller Valsecchi, Thomas Stehlé, Dominic Grün, Asifa Akhtar,
Self-renewal and differentiation of hematopoietic stem cells (HSCs) are orchestrated by the combinatorial action of transcription factors and epigenetic regulators. Here, we have explored the mechanism by which histone H4 lysine 16 acetyltransferase MOF regulates erythropoiesis. Single-cell RNA sequencing and chromatin immunoprecipitation sequencing uncovered that MOF influences erythroid trajectory by dynamic recruitment to chromatin and its haploinsufficiency causes accumulation of a transient ...
Tópico(s): Single-cell and spatial transcriptomics
2020 - American Association for the Advancement of Science | Science Advances
Emese Renczés, Veronika Borbélyová, Manuel Steinhardt, Tim Höpfner, Thomas Stehlé, Daniela Ostatníková, Peter Celec,
Aging in women is associated with low estrogen, but also with cognitive decline and affective disorders. Whether low estrogen is causally responsible for these behavioral symptoms is not clear. Thus, we aimed to examine the role of estradiol in anxiety-like behavior and memory in rats at middle age. Twelve-month old female rats underwent ovariectomy (OVX) or were treated with 1mg/kg of letrozole – an aromatase inhibitor. In half of the OVX females, 10µg/kg of 17β-estradiol was supplemented daily for ...
Tópico(s): Stress Responses and Cortisol
2020 - Frontiers Media | Frontiers in Endocrinology
Michael Storchak, Philipp Rupp, Hans‐Christian Möhring, Thomas Stehle,
The Johnson–Cook constitutive equation is very widely used for simulating cutting processes. Different methods are applied for establishing parameters of the constitutive equation. Based on the methods analysed in this study, two algorithms were worked out to determine the constitutive parameters for the prevailing conditions during cutting processes. In the first algorithm, all constitutive parameters were established simultaneously with standardized test methods. In the second algorithm, the constitutive ...
Tópico(s): Engineering Technology and Methodologies
2019 - Multidisciplinary Digital Publishing Institute | Metals
Philippe Attias, Giovanna Melica, David Boutboul, Nathalie De Castro, Vincent Audard, Thomas Stehlé, Géraldine Gaube, Slim Fourati, Françoise Botterel, Vincent Fihman, Étienne Audureau, Philippe Grimbert, Marie Matignon,
Epidemiology of opportunistic infections (OI) after kidney allograft transplantation in the modern era of immunosuppression and the use of OI prevention strategies are poorly described. We retrospectively analyzed a single-center cohort on kidney allograft adult recipients transplanted between January 2008 and December 2013. The control group included all kidney recipients transplanted in the same period, but with no OI. We analyzed 538 kidney transplantations (538 patients). The proportion of OI ...
Tópico(s): Neurological Complications and Syndromes
2019 - Multidisciplinary Digital Publishing Institute | Journal of Clinical Medicine
Tom Brosch, Jörg Peters, Alexandra Groth, Thomas Stehlé, Jürgen Weese,
Model-based segmentation (MBS) has been successfully used for the fully automatic segmentation of anatomical structures in medical images with well defined gray values due to its ability to incorporate prior knowledge about the organ shape. However, the robust and accurate detection of boundary points required for the MBS is still a challenge for organs with inhomogeneous appearance such as the prostate and magnetic resonance (MR) images, where the image contrast can vary greatly due to the use of ...
Tópico(s): Medical Imaging and Analysis
2018 - Springer Science+Business Media | Lecture notes in computer science
Fabian Wenzel, Carsten Meyer, Thomas Stehlé, Jörg Peters, Susanne Siemonsen, Christian J. Thaler, Lyubomir Zagorchev,
This work presents a novel approach for the rapid segmentation of clinically relevant subcortical brain structures in T1-weighted MRI by utilizing a shape-constrained deformable surface model. In contrast to other approaches for segmenting brain structures, its design allows for parallel segmentation of individual brain structures within a flexible and robust hierarchical framework such that accurate adaptation and volume computation can be achieved within a minute of processing time. Furthermore, ...
Tópico(s): Medical Imaging and Analysis
2018 - Elsevier BV | Medical Image Analysis
Hans‐Christian Möhring, Valerii Kushner, Michael Storchak, Thomas Stehle,
This paper presents methods for refining the calculation of cutting temperatures. The heat flow densities and temperatures in the chip forming area, the accumulation zone and the area of the plastic contact between chip and tool affect the cutting temperature considerably. The new method takes the heat distribution for moving sources into account. The temperature in the contact between the flank face and the workpiece is calculated considering how friction and the accumulation zone affect the cutting ...
Tópico(s): Tunneling and Rock Mechanics
2018 - Elsevier BV | CIRP Annals
Philippe Rémy, Vincent Audard, Pierre André Natella, Gaëlle Pellé, Bertrand Dussol, Hélène Leray‐Moragues, Cécile Vigneau, Khedidja Bouachi, Jacques Dantal, Laurence Vrigneaud, Alexandre Karras, Frank Pourcine, Philippe Gatault, Philippe Grimbert, Nawelle Ait Sahlia, Anissa Moktefi, Éric Daugas, Claire Rigothier, Sylvie Bastuji‐Garin, Dil Sahali, Jean‐Claude Aldigier, Pierre Bataille, Bernard Canaud, Dominique Chauveau, Christian Combe, Gabriel Choukroun, Emilie Cornec-Legall, Karine Dahan, Michel Delahousse, Dominique Desvaux, P. Deteix, Antoine Dürrbach, Vincent Esnault, Marie Essig, P Fiévet, T. Frouget, Dominique Guerrot, M. Godin, Annie Gontiers-Picard, Morgane Gosselin, Catherine Hanrotel‐Saliou, Anne-Elisabeth Heng, Antoine Huart, Antoine Humbert, Tomek Kofman, Aurélie Hummel, Philippe Lang, Maurice Laville, Yannick Le Meur, Paolo Malvezzi, Marie Matignon, Rafik Mesbah, Bruno Moulin, Sandrine Muller, Jérôme Olagne, Agathe Pardon, François Provôt, Guillaume Queffeulou, Emmanuelle Plaisier, Quentin Raimbourg, Philippe Rieu, Thomas Stehlé, P Vanhille,
First-line therapy of minimal change nephrotic syndrome (MCNS) in adults is extrapolated largely from pediatric studies and consists of high-dose oral corticosteroids. We assessed whether a low corticosteroid dose combined with mycophenolate sodium was superior to a standard oral corticosteroid regimen. We enrolled 116 adults with MCNS in an open-label randomized controlled trial involving 32 French centers. Participants randomly assigned to the test group (n=58) received low-dose prednisone (0.5 mg/ ...
Tópico(s): Systemic Sclerosis and Related Diseases
2018 - Elsevier BV | Kidney International
Vincent Audard, Pablo Bartolucci, Thomas Stehlé,
Albuminuria is considered to be a relevant biomarker for the detection of early glomerular damage in patients with sickle cell disease (SCD). Improvements in our understanding of the pathophysiological processes and molecular mechanisms underlying albuminuria are required, because increasing numbers of patients with SCD are developing chronic kidney disease. The early recognition of sickle cell nephropathy (SCN) and studies of the natural course of this emerging renal disease are therefore crucial, ...
Tópico(s): Blood groups and transfusion
2017 - Oxford University Press | Clinical Kidney Journal
Jan T. Benthien, Martin Ohlmeyer, Matthias Schneider, Thomas Stehle,
Tópico(s): Material Properties and Processing
2017 - Springer Science+Business Media | European Journal of Wood and Wood Products
Marion Gauthier, Florence Canouï‐Poitrine, Esther Guéry, Dominique Desvaux, Sophie Hüe, Guillaume Canaud, Thomas Stehlé, Philippe Lang, Tomek Kofman, Philippe Grimbert, Marie Matignon,
In kidney transplant recipients, anticardiolipin (ACL) antibodies without antiphospholipid syndrome (APS) are found in up to 38% of patients and could be associated with thrombotic events (TEs). However, the prognostic role of ACL regarding kidney transplant and patients outcomes have still not been well defined. We conducted an observational, monocentric, retrospective cohort study including 446 kidney transplant recipients and standardized follow-up: 36-month allograft and patient survival, 12-month ...
Tópico(s): Renal Diseases and Glomerulopathies
2017 - Oxford University Press | Nephrology Dialysis Transplantation
Charlotte Hurabielle, Évangéline Pillebout, Thomas Stehlé, Cécile Pagès, J. Roux, Pierre Schneider, Sylvie Chevret, Cendrine Chaffaut, Anne Boutten, Samia Mourah, Nicole Basset‐Séguin, Emmanuelle Vidal‐Petiot, Célèste Lebbe, Martin Flamant,
Serum creatinine has been reported to increase in patients receiving Vemurafenib, yet neither the prevalence nor the mechanism of this adverse event are known.We aimed to evaluate the frequency and the mechanisms of increases in plasma creatinine level in patients receiving Vemurafenib for advanced melanoma.We performed a retrospective monocentric study including consecutive patients treated with Vemurafenib for an advanced melanoma. We collected clinical and biological data concerning renal function ...
Tópico(s): HER2/EGFR in Cancer Research
2016 - Public Library of Science | PLoS ONE