Xiao-Fang Yu, Wei Liu, Jie Chen, Wei Kong, Bindong Liu, Jin-ye Yang, Fuxiong Liang, Francine E. McCutchan, Sucheep Piyasirisilp, Shenghan Lai,
... the recent outbreak of HIV infection in Tianyang, Tiandong, Binyang, and Nanning, we obtained HIV-1 env ... sequences from Tianyang (99TY021, 023, 024 and 027), Tiandong (98TD001–98TD008), Binyang (00BY004–00BY 006), and Nanning ( ... users from Tianyang (99TY021, 023, 024 and 027), Tiandong (98TD001–98TD008), Binyang (00BY004, 00BY005, and 00BY006), and ... drug users from Tianyang (99TY021, 023, and 024), Tiandong (98TD004 and 98TD005), Binyang (00BY004 and 00BY005), and ... Baise and those from Nanning, Binyang, Tianyang, and Tiandong than among drug users from Pingxiang and Nanning. ...
Tópico(s): HIV/AIDS drug development and treatment
2001 - Lippincott Williams & Wilkins | AIDS
Xing-Kui Zhou, Ying Huang, Miao Li, Xiaofei Zhang, Yu-Qian Wei, Qi-Yan Cha, Ti-Kun Zhang, Xuejian Wang, Jian-Jin Liu, Ziyi Liu, Shi-Chun Qin, Ming He Mo,
... isolated from a cave soil sample collected from Tiandong Cave, Guizhou Province, south-west PR China. Cells ...
Tópico(s): Microbial Natural Products and Biosynthesis
2020 - Microbiology Society | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
Yongquan Zhang, Hongchang Gao, Jingshun Wang, Qingguo Chi, Tiandong Zhang, Changhai Zhang, Yu Feng, Yue Zhang, Dianxue Cao, Kai Zhu,
All-solid-state lithium metal batteries (ASSLMBs) are considered the most competitive next-generation energy storage batteries due to their high energy density and high safety.
Tópico(s): Advancements in Battery Materials
2024 - Royal Society of Chemistry | Inorganic Chemistry Frontiers
Chao Yin, Tiandong Zhang, Changhai Zhang, Yue Zhang, Chang Kyu Jeong, Geon‐Tae Hwang, Qingguo Chi,
Abstract High‐temperature energy storage performance of dielectric capacitors is crucial for the next generation of power electronic devices. However, conduction losses rise sharply at elevated temperature, limiting the application of energy storage capacitors. Here, the mica films magnetron sputtered by different insulating layers are specifically investigated, which exhibit the excellent high‐temperature energy storage performance. The experimental results revealed that the PbZrO 3 /Al 2 O 3 /PbZrO ...
Tópico(s): Advanced Sensor and Energy Harvesting Materials
2024 - Wiley | SusMat
Yanan Shang, Yu Feng, Zhaotong Meng, Changhai Zhang, Tiandong Zhang, Qingguo Chi,
By utilizing interchain benzene ring electrostatic interactions in all-organic composite to inhibit dipole relaxation, we have reduced current density and achieved a synergistic effect in improving dielectric and energy storage properties.
Tópico(s): Advanced Sensor and Energy Harvesting Materials
2024 - Royal Society of Chemistry | Materials Horizons
Changhai Zhang, Xu Tong, Zeyang Liu, Yue Zhang, Tiandong Zhang, Chao Tang, Xianli Liu, Qingguo Chi,
In today's contemporary civilization, there is a growing need for clean energy focused on preserving the environment; thus, dielectric capacitors are crucial equipment in energy conversion. On the other hand, the energy storage performance of commercial BOPP (Biaxially Oriented Polypropylene) dielectric capacitors is relatively poor; hence, enhancing their performance has drawn the attention of an increasing number of researchers. This study used heat treatment to boost the performance of the composite ...
Tópico(s): Ferroelectric and Piezoelectric Materials
2023 - Multidisciplinary Digital Publishing Institute | Polymers
Tiandong Zhang, Zhuangzhuang Shi, Chao Yin, Changhai Zhang, Yue Zhang, Yongquan Zhang, Qingguo Chen, Qingguo Chi,
Antiferroelectric PbZrO 3 films have great potential to be used as the energy storage dielectrics due to the unique electric field-induced phase transition character. But the phase transition process always accompanies polarization hysteresis effect that induces large energy loss and lowers the breakdown strength, leading to inferior energy storage density as well as low efficiency. In this work, the synergistical strategies by doping smaller ions of Li + -Al 3+ to substitute Pb 2+ and lowering the ...
Tópico(s): Transition Metal Oxide Nanomaterials
2023 - Springer Science+Business Media | Journal of Advanced Ceramics
Wei Li, Binglei Zhang, Weijie Cao, Wenli Zhang, Tiandong Li, Lina Liu, Linping Xu, Fengcai Gao, Yanmei Wang, Fang Wang, Haizhou Xing, Zhongxing Jiang, Jianxiang Shi, Zhilei Bian, Yongping Song,
BCMA CAR-T is highly effective for relapsed/refractory multiple myeloma(R/R-MM) and significantly improves the survival of patients. However, the short remission time and high relapse rate of MM patients treated with BCMA CAR-T remain bottlenecks that limit long-term survival. The immune microenvironment of the bone marrow (BM) in R/R-MM may be responsible for this. The present study aims to present an in-depth analysis of resistant mechanisms and to explore potential novel therapeutic targets for ...
Tópico(s): Multiple Myeloma Research and Treatments
2023 - BioMed Central | Experimental Hematology and Oncology
Yanan Shang, Yu Feng, Changhai Zhang, Tiandong Zhang, Qingguo Chi,
Flexible dielectric materials have given rise to extensive attention in power electronics and other fields because of their outstanding superiorities such as high-power density. However, how to effectively heighten the energy storage density of the dielectric is a long-term challenge. The single fillers introduced tends to focus on enhancing the insulating or polarized properties of the composite, which limits further improvements in energy storage density. In this paper, through the co-doped of ...
Tópico(s): Ferroelectric and Piezoelectric Materials
2023 - Elsevier BV | Composites Part A Applied Science and Manufacturing
Tao‐Lan Zhang, Chao Xia, Bo‐Wen Zheng, Haihong Hu, Lingxiang Jiang, David Escobar, Bo‐Yv Zheng, Tiandong Chen, Jing Li, Guohua Lv, Wei Huang, Yiguo Yan, Ming‐Xiang Zou,
Abstract Background With cancer-associated fibroblasts (CAFs) as the main cell type, the rich myxoid stromal components in chordoma tissues may likely contribute to its development and progression. Methods Single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, bulk RNA-seq, and multiplexed quantitative immunofluorescence (QIF) were used to dissect the heterogeneity, spatial distribution, and clinical implication of CAFs in chordoma. Results We sequenced here 72 097 single cells from 3 primary ...
Tópico(s): Cancer-related molecular mechanisms research
2023 - Oxford University Press | Neuro-Oncology
Tiandong Zhang, Hai Sun, Chao Yin, Young-Hoon Jung, Seongwook Min, Yue Zhang, Changhai Zhang, Qingguo Chen, Keon Jae Lee, Qingguo Chi,
Polymer-based film capacitors have attracted increasing attention due to the rapid development of new energy vehicles, high-voltage transmission, electromagnetic catapults, and household electrical appliances. In recent years, all-organic polymers, polymer nanocomposites, and multilayer films have proposed to address the inverse relationship between dielectric constant and electric breakdown strength, reduce the polarization loss and high-temperature conduction loss of polymer dielectric films. ...
Tópico(s): Ferroelectric and Piezoelectric Materials
2023 - Elsevier BV | Progress in Materials Science
Yue Zhang, Xin He, Xiuchun Cong, Qi Wang, Huajie Yi, Sen Li, Changhai Zhang, Tiandong Zhang, Xuan Wang, Qingguo Chi,
Polyethersulfone (PESU) has distinctive features of great breakdown strength and low dielectric loss. However, some factors limit the practical application of PESU dielectric materials in the field of energy storage, for instance, the low energy storage density, polarization strength and dielectric constant of PESU. In this work, ZnO nano-shell and BFSTO nano-shell coated BZCT are successfully synthesized, respectively, using the hydrothermal method. Compared to the pure PESU and BZCT/PESU, discharged ...
Tópico(s): Electromagnetic wave absorption materials
2023 - Elsevier BV | Journal of Alloys and Compounds
Zhaotong Meng, Tiandong Zhang, Changhai Zhang, Yanan Shang, Qingquan Lei, Qingguo Chi,
Dielectric capacitors have been developed for nearly a century, and all-polymer film capacitors are currently the most popular. Much effort has been devoted to studying polymer dielectric capacitors and improving their capacitive performance, but their high conductivity and capacitance losses under high electric fields or elevated temperatures are still significant challenges. Although many review articles have reported various strategies to address these problems, to the best of current knowledge, ...
Tópico(s): Ferroelectric and Piezoelectric Materials
2023 - | Advanced Materials
Changhai Zhang, Zeyang Liu, Tiandong Zhang, Xubin Wang, Chao Yin, Xianli Liu, Qingguo Chi,
Abstract The packaging insulation material was a crucial component to guarantee the stable and safe operation of electronic devices. Epoxy resin, one of the most popular packaging materials, was widely used as an electronic packaging material because of its good corrosion resistance and electrical insulation, low price, and easy processing and molding. However, the unsatisfied heat resistance cannot meet the requirements of the rapid development of third‐generation power semiconductors, so it was ...
Tópico(s): Synthesis and properties of polymers
2023 - Wiley | Journal of Applied Polymer Science
Jingshun Wang, Yongquan Zhang, Guang Liu, Tiandong Zhang, Changhai Zhang, Yue Zhang, Yu Feng, Qingguo Chi,
Abstract Magnesium‐ion batteries are widely studied for its environmentally friendly, low‐cost, and high volumetric energy density. In this work, the solvothermal method is used to prepare titanium dioxide bronze (TiO 2 ‐B) nanoflowers with different nickel (Ni) doping concentrations for use in magnesium ion batteries as cathode materials. As Ni doping enhances the electrical conductivity of TiO 2 ‐B and promotes magnesium ion diffusion, the band gap of TiO 2 ‐B host material can be significantly reduced, ...
Tópico(s): Supercapacitor Materials and Fabrication
2023 - Wiley | Small
Xincheng Liu, Cui Guo, Tiandong Leng, Zhen Fan, Jialuo Mai, Jiehong Chen, Jinhai Xu, Qianyi Li, Bin Jiang, Ke Sai, Wenzhuo Yang, Jiayu Gu, Jingyi Wang, Shuxin Sun, Zhijie Chen, Yingqian Zhong, Xuanming Liang, Chaoxin Chen, Jing Cai, Yuan Lin, Jiankai Liang, Jun Hu, Guangmei Yan, Wenbo Zhu, Wei Yin,
Abstract Differentiation therapy using small molecules is a promising strategy for improving the prognosis of glioblastoma (GBM). Histone acetylation plays an important role in cell fate determination. Nevertheless, whether histone acetylation in specific sites determines GBM cells fate remains to be explored. Through screening from a 349 small molecule-library, we identified that histone deacetylase inhibitor (HDACi) MS-275 synergized with 8-CPT-cAMP was able to transdifferentiate U87MG GBM cells ...
Tópico(s): Protein Degradation and Inhibitors
2023 - Springer Nature | Cell Death and Disease
Yanfeng Lu, Peiyi Zhao, Yajun Chen, Tiandong Huang, Yunlan Liu, Dan Ding, Guangxian Zhang,
A novel phosphorus-containing flame retardant, ammonium starch phosphate (ASTP) based on biomass starch, was synthesized for cotton fabrics, and its structure was characterized by 1D and 2D NMR. The limiting oxygen index (LOI) of the cotton fabric treated with 30 % ASTP reached 45.2 %, and the LOI remained at 32.1 % after 50 laundry cycles, indicating that the cotton fabrics treated with ASTP had a high flame retardancy and semi-permanent wash durability. The semi-permanent wash durability, Fourier transform ...
Tópico(s): Synthesis of Organic Compounds
2022 - Elsevier BV | Carbohydrate Polymers
Yanan Shang, Yu Feng, Changhai Zhang, Tiandong Zhang, Qingquan Lei, Qingguo Chi,
By reasonably adjusting two-dimensional filler double gradient distribution, the restrictive relationship between breakdown strength and dielectric constant is balanced, and the synergistic improvement of breakdown and polarization is realized.
Tópico(s): Electromagnetic wave absorption materials
2022 - Royal Society of Chemistry | Journal of Materials Chemistry A
Qiyuan Cao, Rui Wang, Tiandong Zhang, Yu Wang, Shuo Wang,
In this paper, the hydrodynamic modeling and parameter identification of the RobDact, a bionic underwater vehicle inspired by Dactylopteridae, are carried out based on computational fluid dynamics (CFD) and force measurement experiment. Firstly, the paper briefly describes the RobDact, then establishes the kinematics model and rigid body dynamics model of the RobDact according to the hydrodynamic force and moment equations. Through CFD simulations, the hydrodynamic force of the RobDact at different ...
Tópico(s): Robotic Locomotion and Control
2022 - American Association for the Advancement of Science | Cyborg and Bionic Systems
Luxiang Ma, Tiandong Chen, Chunxi Hai, Shengde Dong, Xin He, Qi Xu, Hang Feng, Xin Ao, Jitao Chen, Yuan Zhou,
Tópico(s): Advanced Battery Materials and Technologies
2022 - Springer Science+Business Media | Tungsten
Tiandong Zhang, Hainan Yu, Young Hoon Jung, Changhai Zhang, Yu Feng, Qingguo Chen, Keon Jae Lee, Qingguo Chi,
Biaxially oriented polypropylene (BOPP) is one of the most commonly used commercial capacitor films, but its upper operating temperature is below 105 °C due to the sharply increased electrical conduction loss at high temperature. In this study, growing an inorganic nanoscale coating layer onto the BOPP film's surface is proposed to suppress electrical conduction loss at high temperature, as well as increase its upper operating temperature. Four kinds of inorganic coating layers that have different ...
Tópico(s): Ferroelectric and Piezoelectric Materials
2022 - Wiley | Energy & environment materials
Huajian Zhu, Yuchen Tan, Chen He, Yang Liu, Yiping Duan, Wenjian Zhu, Tiandong Zheng, Dahong Li, Jinyi Xu, Dong‐Hua Yang, Zhe‐Sheng Chen, Shengtao Xu,
Most vascular disrupting agents (VDAs) fail to prevent the regrowth of blood vessels at the edge of tumors, causing tumor rebound and relapse. Herein, a series of novel multifunctional vascular disrupting agents (VDAs) capable of inhibiting microtubule polymerization and histone deacetylases (HDACs) were designed and synthesized using the tubulin polymerization inhibitor TH-0 as the lead compound. Among them, compound TH-6 exhibited the most potent antiproliferative activity (IC50 = 18–30 nM) against ...
Tópico(s): Click Chemistry and Applications
2022 - American Chemical Society | Journal of Medicinal Chemistry
Tiandong Kong, Lu Chen, Xiaoli Zhao, Fangfang Duan, Hanli Zhou, Lei Wang, Danna Liu,
Tópico(s): Neutropenia and Cancer Infections
2022 - Springer Science+Business Media | Investigational New Drugs
Junyin Li, Yan Liu, Jin Liu, Xian Cui, Tiandong Hou, Dongdong Cheng,
Chemical synthetic slow release fertilizer had become a major breakthrough in the green fertilizer industry due to its superior nutrient management and degradation properties. However, the traditional chemical synthetic slow release fertilizers contain only nitrogen and consume high energy during drying. Herein, a low cost green chemical synthetic slow release fertilizer (PSRF/KCl) was prepared from urea, formaldehyde and diammonium phosphate by spray drying method. Compared with the traditional ...
Tópico(s): Graphene and Nanomaterials Applications
2022 - Elsevier BV | The Science of The Total Environment
Tiandong Wang, Xiaoyue Lin, Fan Sheng,
The literature on leadership is increasingly supporting the power of digital leadership in promoting corporate innovation. In spite of this, digital leadership is a noticeable omission from the literature. As such, in this study, we developed a model based on a resource-based view and social information processing theory to examine the roles of digital entrepreneurial orientation and digital organizational culture in the relationship between digital leadership and exploratory innovation. We examined ...
Tópico(s): Business and Economic Development
2022 - Frontiers Media | Frontiers in Psychology
Tiandong Zhang, Lianyin Yang, Changhai Zhang, Yu Feng, Jian Wang, Zhonghui Shen, Qingguo Chen, Qingquan Lei, Qingguo Chi,
With the rapid development of next-generation electrical power equipment and microelectronics, there is an urgent demand for dielectric capacitor films which can work efficiently under extreme conditions. However, sharply increased electrical conduction and drastically degrading electric breakdown strength are inevitable at elevated temperatures. Herein, a facile but effective method is proposed to improve high temperature capacitive performance. We report that utilizing an inorganic insulation ...
Tópico(s): Ferroelectric and Piezoelectric Materials
2022 - Royal Society of Chemistry | Materials Horizons
Mengjia Feng, Yu Feng, Changhai Zhang, Tiandong Zhang, Xu Tong, Qiang Gao, Qingguo Chen, Qingguo Chi,
Optimizing the high‐temperature energy storage characteristics of energy storage dielectrics is of great significance for the development of pulsed power devices and power control systems. Selecting a polymer with a higher glass transition temperature ( T g ) as the matrix is one of the effective ways to increase the upper limit of the polymer operating temperature. However, current high‐ T g polymers have limitations, and it is difficult to meet the demand for high‐temperature energy storage dielectrics ...
Tópico(s): High voltage insulation and dielectric phenomena
2022 - Wiley | Energy & environment materials
Guang Liu, Qingquan Lei, Yu Feng, Changhai Zhang, Tiandong Zhang, Qingguo Chen, Qingguo Chi,
Abstract Dielectric capacitors have a high power density, and are widely used in military and civilian life. The main problem lies in the serious deterioration of dielectric insulation performance at high temperatures. In this study, a polycarbonate (PC)‐based energy storage dielectric was designed with BN/SiO 2 heterojunctions on its surface. Based on this structural design, a synergistic suppression of the carrier injection and transport was achieved, significantly improving the insulating properties ...
Tópico(s): Ferroelectric and Piezoelectric Materials
2022 - Wiley | InfoMat
Mengjia Feng, Yu Feng, Changhai Zhang, Tiandong Zhang, Qingguo Chen, Qingguo Chi,
An improved composite dielectric with an excellent high-temperature energy storage performance has been obtained by modulating the trap parameters.
Tópico(s): Advanced Sensor and Energy Harvesting Materials
2022 - Royal Society of Chemistry | Materials Horizons
Qingguo Chi, Xinle Zhang, Xubin Wang, Changhai Zhang, Yongquan Zhang, Chao Tang, Zhonghua Li, Tiandong Zhang,
With the rapid development of the third generation of wide bandgap semiconductor devices, there is an urgent need for highly thermally conductive and electrically insulating packaging materials to solve the heat dissipation problem in the microelectronic devices. In this work, the three-dimensional boron nitride (3D-BN) is successfully constructed by using a facile method, where the healthy and non-toxic food-grade material, curdlan, is used to provide a stable skeletons for growing 3D-BN using an ...
Tópico(s): Aerogels and thermal insulation
2022 - Elsevier BV | Composites Communications