Emilio Pintor Holguín, Marcelo Sanmartı́n, Luís Azcona, Rosana Hernández, Arturo Fernández-Cruz, Carlos Macaya,
La combinación de ticlopidina y aspirina como tratamiento de elección para evitar la formación de trombos después de la implantación de un stent ... leucocitoclástica en probable relación con la administración de ticlopidina. In the last five years the combination of ...
Tópico(s): Antiplatelet Therapy and Cardiovascular Diseases
2001 - Elsevier BV | Revista Española de Cardiología
F Balsano, P Rizzon, Francesco Violi, Domenico Scrutinio, Claudio Cimminiello, F Aguglia, C Pasotti, G Rudelli,
We conducted a controlled multicenter trial with central randomization and evaluation of events under blind conditions involving 652 patients with unstable angina. Patients were treated either with conventional therapy alone (group C) (n = 338) or with conventional therapy combined with an inhibitor of platelet aggregation, ticlopidine 250 mg b.i.d. (group C + T) (n = 314). Patients were assigned randomly within 48 hours of admission and followed up for 6 months. With the "intention-to-treat" approach, the ...
Tópico(s): Diabetes Treatment and Management
1990 - Lippincott Williams & Wilkins | Circulation
Juan V. Llau, Raquel Ferrandis, C. López Forte,
... se encuentran tanto los antiagregantes plaquetarios (aspirina, clopidogrel, ticlopidina) como los anticoagulants (acenocumarol, warfarina, heparina de bajo ...
Tópico(s): Atrial Fibrillation Management and Outcomes
2009 - Elsevier BV | Cirugía Española
Lisa C. Adams, G. Jeffrey, Bastiaan DeBoer, George Garas,
... angina. A controlled multicenterclinical trial. The Studio della Ticlopidina nell'Angina Instablile Group. Circulation 1990; 82: 17− ...
Tópico(s): Drug Transport and Resistance Mechanisms
2002 - Wiley | Internal Medicine Journal
Produção Nacional
Revisado por pares
Marcelo Pereira da Rosa, Gislaine Baroni, Vera Lúcia Portal,
... ao ácido acetilsalicílico (AAS), ao clopidogrel ou à ticlopidina 6,7 , mesmo nas diversas combinações desses 8 . ...
Tópico(s): Protease and Inhibitor Mechanisms
2006 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Juan Carlos López‐Gutiérrez, M.P. Calderón Romero,
... resolvió con la administración de ácido acetilsalicílico y ticlopidina aun sin la desaparición del tumor. El cuarto ...
Tópico(s): Vascular Malformations Diagnosis and Treatment
2005 - Elsevier BV | Anales de Pediatría
... A controlled multicenter clinical trial. The Studio della Ticlopidina nell'Angina Instabile Group. Circulation. 1990; 82:17- ...
Tópico(s): Heparin-Induced Thrombocytopenia and Thrombosis
1996 - American College of Physicians | Annals of Internal Medicine
Ana María del Pino, Francisco J. de Abajo, Dolores Montero, Mariano Madurga, Gloria Martín-Serrano,
Tópico(s): Diabetes Treatment and Management
2000 - Elsevier BV | Medicina Clínica
V. Gómez Juanes, Milagros Villar, S. Fidalgo González, J.A. Fernández Gómez, M.J. Calvo Alcántara, M.A. de Marino Gómez-Sandoval, Caterina Vicens,
... desviación negativa respecto al valor estándar. AAS y ticlopidina suponen un 74% de los antiagregantes plaquetarios. El ...
Tópico(s): Medication Adherence and Compliance
2000 - Elsevier BV | Atención Primaria
Ángeles E. Pizarro, Raúl J. Andrade, Miren García‐Cortés, M. Isabel Lucena, J M Pérez-Moreno, M.M. Puertas, Herminia Sanchez-Martinez, JL Montero, José Antonio Durán, M Jiménez, A Ruiz-Montero, M J Soto-Conesa, Luı́s Rodrigo, Ruth de Francisco, R. Alcántara, Rogério Camargo,
To analyze the characteristics of hepatotoxicity due to ticlopidine.We describe all the case of hepatotoxicity attributed to ticlopidine and reported to the Register of drug associated hepatopathies. We also obtained data from MEDLINE and the Spanish Medical Index regarding cases reported during the period 1982 2001.We reported twelve cases of hepatopathy related to the use of ticlopidine. These made up 5% of all the cases notified to the Register. Eighty three percent of the patients were male, ...
Tópico(s): Drug Transport and Resistance Mechanisms
2001 - Viguera Publishers | Revista de Neurología
Pilar García Ortega, Juan José Navarro, Alfonso Carvajal, Javier García del Pozo,
Tópico(s): Clinical Nutrition and Gastroenterology
2001 - Elsevier BV | Medicina Clínica
Núria López Ariztegui, M. C. Ochoa, M J Sánchez-Migallón, C. Nevado, Melinda S. Martin,
Ticlopidine and phenytoin are two drugs which are widely used in everyday clinical practice, the first as a platelet anti-aggregant and the second as an anti-epileptic agent. Their association is not uncommon, since there is a high incidence of epileptic crises of vascular origin in adults.We present the case of a 77 year old man who had been treated for twenty years with phenytoin for partial crises secondary to a left frontal hematoma. He then followed treatment with ticlopidine for a femoropopliteal ...
Tópico(s): Epilepsy research and treatment
1998 - Viguera Publishers | Revista de Neurología
... F, Pasotti C, Rudelli G, the Studio della Ticlopidina nell'Angina Instabile Group. Antiplatelet treatment with ticlopidine ...
Tópico(s): Cardiac Imaging and Diagnostics
1998 - Lippincott Williams & Wilkins | Circulation
L. Michael Prisant, Thomas von Dohlen, Ward Rogers, Lauren C. Houghton, Albert A. Carr, Martin J. Frank,
... Pasotti C, Rudelli G and the studio della Ticlopidina nell' Angina Instabile Group: Anti platelet treatment with ...
Tópico(s): Hormonal Regulation and Hypertension
1992 - Wiley | The Journal of Clinical Pharmacology
Arshad Majid, Norman Delanty, Jonathan Kantor,
... científicas internacionales. Los términos claves utilizados fueron: aspirina, ticlopidina, dipiridamol, antiplaquetario y clopidogrel.SELECCIÓN DE FUENTES DE ... terapia alternativa eficaz y segura comparada con la ticlopidina, y carece de algunos de los efectos adversos serios asociados al uso de la ticlopidina. Sin embargo, ha demostrado ser inferior a la ...
Tópico(s): Lipoproteins and Cardiovascular Health
2001 - SAGE Publishing | Annals of Pharmacotherapy
Domingo A. Pascual‐Figal, Mariano Valdés Chávarri, José López Candel, Tomás Vicente, Fernando Pérez Lorente, Arcadio García Alberola, Juan A. Ruipérez,
... 2,2 atm) y tratamiento con aspirina y ticlopidina durante un mes. La tasa de éxito del ...
Tópico(s): Acute Myocardial Infarction Research
2000 - Elsevier BV | Revista Española de Cardiología
Francisco Domingo, Emilio Pérez Fernández, Aurelio Quesada Dorador, Felipe Atienza, Juan Vicente Vilar Herrero, Ildefonso Echánove Errazti, José de Velasco Rami,
... heparinizados durante 72 h y recibieronterapéutica antiagregante con ticlopidina yaspirina. Se consiguió restaurar la permeabilidaddel vaso con ...
Tópico(s): Cardiac Valve Diseases and Treatments
1997 - Elsevier BV | Revista Española de Cardiología
A. Diaz Fuenzalida, Hernan Gonzalo Valdes Socin, O Laudano, Alejandra Avagnina, Jorge Findor,
Tópico(s): Biliary and Gastrointestinal Fistulas
1997 - Elsevier BV | Gastroenterología y Hepatología
Thomas L. Lenz, Daniel E. Hilleman,
... efectividad relativa de aspirina/dipiridamole-LE comparada con ticlopidina y clopidogrel aún está por determinarse. Como terapia antiplaquetaria alterna, el CAMT recomienda clopidogrel sobre ticlopidina debido a una incidencia menor de efectos adversos. ...
Tópico(s): Inflammatory mediators and NSAID effects
2000 - SAGE Publishing | Annals of Pharmacotherapy
Luis Martínez Elbal, José-Ramón López Mínguez, Manuel Axolohua Sánchez Alonso, Isabel Calvo, Luis Insa, Román Lezaún, Thierry Colman, E Esplugas, Nicolás Vazquez, Francisco Picó, A Amaro,
... tratados con aspirina (125-325 mg/día) y ticlopidina (250 mg/12 h durante cuatro semanas). Tras ... Wiktor es óptimo, la terapia con aspirina y ticlopidina exclusivamente se acompaña de un índice muy bajo ...
Tópico(s): Cardiac Imaging and Diagnostics
1998 - Elsevier BV | Revista Española de Cardiología
... La agregacion plaquetaria inducida porlipopolisacarido es inhibida por ticlopidina. Investigamos si ticlopidina podia modificar el efecto de la interaccion lipopolisacarido - ... plasma rico en plaquetas de ratas pretratadas con ticlopidina; lipopolisacarido + solucion de ticlopidina; lipopolisacarido + plasma rico en plaquetas + solucion de ticlopidina; solucion de ticlopidina. Se evidencio dano celular con lipopolisacarido, que se ... rico en plaquetas procedente de ratas pretratadas con ticlopidina, estas alteraciones no estuvieron presentes. En conclusion ticlopidina ...
Tópico(s): Hyperglycemia and glycemic control in critically ill and hospitalized patients
2007 - National University of Colombia | Revista de la Facultad de Medicina
Produção Nacional
Revisado por pares
Anis Rassi, Vicente Amato Neto, Gustavo Gabriel Rassi, F. Ferriolli Filho, Valdir Sabbaga Amato,
Em investigação experimental, a ticlopidina mostrou ser ativa no sentido de diminuir a parasitemia e a mortalidade quando avaliada a infecção de camundongos pelo Trypanosoma ...
Tópico(s): HIV/AIDS drug development and treatment
2000 - Brazilian Society of Tropical Medicine | Revista da Sociedade Brasileira de Medicina Tropical
FBalsano, PRizzon, FVioli, DScrutinio, CCimminiello, FAguglia, CPasotti, GRudelli,
We conducted a controlled multicenter trial with central randomization and evaluation of events under blind conditions involving 652 patients with unstable angina. Patients were treated either with conventional therapy alone (group C) (n = 338) or with conventional therapy combined with an inhibitor of platelet aggregation, ticlopidine 250 mg b.i.d. (group C + T) (n = 314). Patients were assigned randomly within 48 hours of admission and followed up for 6 months. With the intention-to-treat approach, the ...
Tópico(s): Lipoproteins and Cardiovascular Health
1990 - Lippincott Williams & Wilkins | Circulation
Francesco Violi, Claudio Cimminiello, S Chierichetti, M Scatigna, P Rizzon, F Balsano,
The treatment of patients suffering from unstable angina (UA) with antiplatelet drugs is a therapeutic approach that provided interesting results. Patients given aspirin, that inhibits cyclooxigenase pathway (CP) showed a significant reduction of cardiovascularevents. Quite surprisingly sulfinpirazone, that possesses a mechanism of action similar to aspirin, did not influence cardiovascular complications of UA patients. To further investigate the role of platelets in UA patients, we planned to study ...
Tópico(s): Cardiac Valve Diseases and Treatments
1987 - Thieme Medical Publishers (Germany) | Thrombosis and Haemostasis
José Antônio Franchini Ramires, Antônio de Pádua Mansur, José Renato M Martins, A Raineri, Luı́z Antonio Machado César, Giovanni Bellotti, Dalton de Alencar Fischer Chamone, Fúlvio Pileggi,
Tópico(s): Antiplatelet Therapy and Cardiovascular Diseases
1991 - Sociedade Brasileira de Cardiologia (SBC) | Arquivos Brasileiros de Cardiologia
Pilar Vaquerizo, Julián Solís García del Pozo, Pauline Hernandez,
Tópico(s): Metabolism and Genetic Disorders
2002 - SciELO | Anales de Medicina Interna
Carolina Ruiz B, Tatiana Monroy A, Nelson Montaña N, Pilar Lora L, Rubén Lamich B, Alejandro Valderrama R,
We report a 58 years old male that developed a bone marrow aplasia associated to the use of ticlopidine, prescribed after coronary artery stenting. The patient developed a pneumonia as a complication. He was admitted to the Intermediate Treatment Unit, receiving wide spectrum antimicrobial therapy and a granulocyte colony stimulating factor (Neupogen(r)) with favourable response. Ticlodipine is an effective antiplatelet agent, but has serious hematological and other side effects. Its prescription ...
Tópico(s): Pneumocystis jirovecii pneumonia detection and treatment
2002 - Q16635223 | Revista médica de Chile
Torre Lima F. J. de la, J. L. Prada Parda, Ma R. López López, Alfonso del Arco,
pelvi-crural al final del embarazo, y que curan de forma espontánea.El estudio analítico es habitualmente normal y, en ocasiones, pueden observarse alteraciones propias del último tercio del embarazo.La radiografía al inicio es normal, pero entre 1-2 meses se observa una desmineralización habitualmente homogénea, a diferencia de las localizaciones periféricas de la DSR, sin encontrar alteración de la interlínea articular.La gammagrafía muestra, de manera precoz, una hipercaptación del isótopo en ...
Tópico(s): Hematological disorders and diagnostics
2002 - SciELO | Anales de Medicina Interna
Alberto Sánchez Romero, Rafael García Delgado, José Antonio Durán Quintana,
We report a case in which the association between ticlopidine, nifedipine and phenobarbital was linked with a higher than expected phenobarbital concentration in serum, which suggested a possible interaction between these drugs.A 67 year old male who received treatment with phenobarbital, digoxin, nifedipine, ticlopidine, paroxetine and clorazepate dipotassium. The first control of the level of phenobarbital in serum was performed without any symptoms or signs of toxicity or ineffectiveness. A phenobarbital ...
Tópico(s): Pharmacological Effects and Toxicity Studies
2003 - Viguera Publishers | Revista de Neurología
Giorgio Baralis, Giuseppe Steffenino, Antonio Dellavalle, Eugenio La Scala, E Uslenghi,
Tópico(s): Coronary Interventions and Diagnostics
2003 - Italian Society of Cardiac Surgery | Giornale italiano di cardiologia