Renata Bocian, Paulina Kaźmierska, Paulina Kłos‐Wojtczak, Tomasz Kowalczyk, Jan Konopacki,
Previous in vivo data suggested that orexin neuropeptides (ORX(A) and ORX(B) ) synthetized in hypothalamic neurons were involved in the mechanism of generation of the hippocampal formation theta rhythm. Surprisingly, this suggestion has never been directly proved by experiments using intraseptal or intrahippocampal administration of orexins. In this study, involving the use of in vitro hippocampal formation slices and in vivo model of anesthetized rat, we provide the first convergent electropharmacological ...
Tópico(s): Sleep and related disorders
2015 - Wiley | Hippocampus
Mateusz Zelent, Nadeem Tahir, R. Gieniusz, Jarosław W. Kłos, Tomasz Wojciechowski, U. Guzowska, A. Maziewski, Jun Ding, A. O. Adeyeye, Maciej Krawczyk,
We have investigated theoretically (with micromagnetic simulations and plane wave method) and experimentally (with ferromagnetic resonance and Brillouin light scattering) three types of antidot lattices (ADLs) based on permalloy thin films with increased complexity of the unit cell: simple square, bi-component square and wave-like ADL. We have found that placing a small additional antidot in the center of the unit cell of the square ADL modify significantly the spin wave spectrum and its dependence ...
Tópico(s): Physics of Superconductivity and Magnetism
2017 - Institute of Physics | Journal of Physics D Applied Physics
Anna Janicka-Kłos, Tomasz Janek, Joanna Burger, Hanna Czapor‐Irzabek,
Mucin 7 (called MUC7 or MG2) is a salivary protein whose fragments exhibit a strong antimicrobial activity and is a natural protection of organisms against pathogens. Up to date however the exact mechanism of their actions is unknown. One hypothesis covers an involvement of biologically occurring metal ions in this process. Herein, three 12-mer peptides have been included in the study, one of which (mother-peptide sequence, L3) is a direct analogue of a fragment naturally cut out from the MUC7 (with ...
Tópico(s): Chemical Synthesis and Analysis
2019 - Elsevier BV | Journal of Inorganic Biochemistry
Aneta Lewicka, Sławomir Lewicki, Anna Kłos, Bogdan Dębski, Tomasz Kurył, Jerzy Bertrandt,
[b]Introduction[/b]. Prolonged shortages of protein in the diet significantly alter the composition and content of polyunsaturated fatty acids (PUFA) in tissues and body fluids. One of nutritional factors which may reduce negative effects of protein malnutrition might be vitamin B[sub]2[/sub] due to its influence on lipids metabolism. [b]Objective. [/b]The aim of the study was to investigate the influence of low protein (LP) diet enriched with vitamin B[sub]2[/sub] on the content and composition of PUFA ...
Tópico(s): Fatty Acid Research and Health
2017 - Institute of Rural Health | Annals of Agricultural and Environmental Medicine
Izabela Skibińska, Marek Tomaszewski, Mirosław Andrusiewicz, Paulina Urbaniak, Roza Czarnecka-Klos, Milud Shadi, Tomasz Kotwicki, Małgorzata Kotwicka,
The aim of this study was to detect and assess the estrogen receptor (ESR) coactivator PELP1 expression within human paraspinal skeletal muscles in patients suffering from idiopathic scoliosis.During surgical correction of scoliosis the muscle biopsies harvested in 29 females. Presence of PELP1, ESR1 and ESR2 genes transcripts was studied using RT-qPCR technique while immunohistochemistry and western blot methods were used to detect the PEPL1 protein presence.PELP1 expression in deep paraspinal muscles ...
Tópico(s): Pregnancy-related medical research
2016 - Public Library of Science | PLoS ONE
Bohdan Kłos, Ryszard Kokoszczyński, Tomasz Łyziak, Jan Przystupa, Ewa Wróbel,
The paper presents the procedure and two structural macroeconometric models used at the National Bank of Poland for producing regular quarterly inflation projections. One of the models is a small macroeconomic model based on the New Keynesian Phillips curve, the IS curve and the exchange rate equation based on uncovered interest parity with risk factors. The other, more disaggregated model, explicitly focuses on the supply side and separates the steady state from short-term adjustments.
Tópico(s): Global Financial Crisis and Policies
2005 - RELX Group (Netherlands) | SSRN Electronic Journal
Patrycja Krzyżanowska-Jankowska, Janusz Książyk, Małgorzata Kocielińska-Kłos, Elżbieta Banaś, Małgorzata Kaleta, Katarzyna Popińska, Tomasz Szczapa, Jarosław Walkowiak,
Tópico(s): Vitamin C and Antioxidants Research
2012 - Elsevier BV | Clinical Nutrition
T. Ciesielczuk, Tomasz Olszowski, Marcin Prokop, A. Kłos,
Abstract The moss Pleurozium schreberi was used to evaluate the emission of polycyclic aromatic hydrocarbons (PAHs) at Polish cemeteries on the All Saints' Day, when Poles traditionally light candles and candle lamps in memory of the deceased. Moss samples were exposed for 7 days at 4 cemeteries and, for comparison, in a city centre and in a rural area. During exposition, the mean content of 16 monitored PAHs in the samples increased by 455 ng/g at the cemeteries and by 689 ng g -1 in the city centre. ...
Tópico(s): Botany and Plant Ecology Studies
2012 - De Gruyter | Ecological Chemistry and Engineering S
Joanna Klos, Elwira Śliwińska, Adam Kula, Hieronim Golczyk, Aleksandra Grabowska-Joachimiak, Tomasz Ilnicki, Krzysztof Szostek, Alan V. Stewart, Andrzej Joachimiak,
The subgenus Ceratochloa of the genus Bromus includes a number of closely related allopolyploid forms or species that present a difficult taxonomic problem. The present work combines data concerning chromosome length, heterochromatin distribution and nuclear genome size of different 6x, 8x and 12x accessions in this subgenus. Special attention is paid to the karyotype structure and genomic constitution of duodecaploid plants recently found in South America. Hexaploid lineages possess six almost ...
Tópico(s): Plant tissue culture and regeneration
2009 - Brazilian Society of Genetics | Genetics and Molecular Biology
Wojciech Pluskiewicz, Piotr Adamczyk, Edward Franek, Piotr Leszczyński, Ewa Sewerynek, Hanna Wichrowska, Luiza Napiórkowska, Tomasz Kostyk, Michał Stuss, Wioletta Stępień-Kłos, Krzysztof S. Gołba, Bogna Drozdzowska,
The aim of the cross-sectional study was to establish the degree of conformity between 10-year probability of osteoporotic fracture, assessed by FRAX, and using the nomograms, as proposed by Nguyen at al.Postmenopausal Polish women (2012) were examined in their mean age of 68.5+/-7.9 years (age range 55-90 years). Fracture probability by FRAX was based on age, BMI, prior fracture, hip fracture in parents, steroid use, rheumatoid arthritis, alcohol use, secondary osteoporosis and T-score for femoral ...
Tópico(s): Bone health and treatments
2010 - Elsevier BV | Bone
Anna Janicka-Kłos, Hanna Czapor‐Irzabek, Tomasz Janek,
Mucin 7 (encoded byMUC7) is a human salivary protein that has a role in the natural immune system. Fragments of mucin 7 exhibit antimicrobial activity against bacteria and yeast. Although the antimicrobial properties of peptides have been known and studied for decades, the exact mechanism of action of antimicrobial peptides (AMPs) is still unclear. It is known that some AMPs require divalent metal ions to activate their activity. Herein, we investigated three 15-mer MUC7 peptides, one of which (mother ...
Tópico(s): Protein Hydrolysis and Bioactive Peptides
2021 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Beata Tylińska, Anna Janicka-Kłos, Tomasz Gębarowski, Paulina Nowotarska, Stanisława Plińska, Benita Wiatrak,
Pyrimidine derivatives exhibit a wide range of biological activities, including anti-inflammatory properties. The aim of this study was to investigate the effects of tested pyrimidine derivatives on the activity of cyclooxygenase isoenzymes (COX-1 and COX-2), antioxidant properties, and their ability to inhibit the growth of inflammatory cells. In vitro tests were conducted to assess the ability of pyrimidine derivatives L1–L4 to inhibit COX-1 and COX-2 activity using the TMPD oxidation assay (N,N, ...
Tópico(s): Inflammatory mediators and NSAID effects
2024 - Multidisciplinary Digital Publishing Institute | International Journal of Molecular Sciences
Tomasz Żarnowski, Maria Tulidowicz-Bielak, Klos-Rola,
Background: The aim of this study was to evaluate the influence of topical bevacizumab on the formation and function of filtering blebs in eyes with early bleb failure after antiglaucoma surgery. Methods: Of all patients who underwent mitomycin-augmented trabeculectomy for glaucoma in the Department of Ophthalmology at the Medical University in Lublin, Poland, between March 2009 and March 2010, a total of 21 eyes from 20 patients with injected filtration bleb 9.8 ± 4.7 days after surgery were included ...
Tópico(s): Retinal and Macular Surgery
2013 - Dove Medical Press | Clinical ophthalmology
Jan Konopacki, Renata Bocian, Tomasz Kowalczyk, Paulina Kłos‐Wojtczak,
Gap junctions (GJs) were discovered more than five decades ago, and since that time enormous strides have been made in understanding their structure and function. Despite the voluminous literature concerning the function of GJs, the involvement of these membrane structures in the central mechanisms underlying oscillations and synchrony in the neuronal network is still a matter of intensive debate. This review summarizes what is known concerning the involvement of GJs as electrical synapses in mechanisms ...
Tópico(s): Nicotinic Acetylcholine Receptors Study
2014 - Elsevier BV | Brain Research Bulletin
Zbigniew Heleniak, Magdalena Cieplińska, Tomasz Szychliński, Dymitr Rychter, Kalina Jagodzińska, Alicja Kłos, Izabela Kuźmiuk, Marzena Tylicka, Leszek Tylicki, Piotr Rutkowski, Alicja Dębska‐Ślizień,
Nonsteroidal anti-inflammatory drugs (NSAIDs) are the cornerstone of pain management. There are no detailed data on NSAIDs use in Poland, especially in patients with chronic kidney disease (CKD). The aim of this study was to evaluate the frequency, circumstances, and causes of NSAIDs use as well as knowledge of their side-effects in patients with CKD. This cross-sectional study was conducted in 972 individuals with CKD, enrolled in a written survey originally developed by the authors. There were 574 ...
Tópico(s): Pharmacological Effects and Toxicity Studies
2016 - Springer Science+Business Media | Journal of Nephrology
Renata Bocian, Paulina Kłos‐Wojtczak, Bartosz Caban, Tomasz Kowalczyk, Paulina Kaźmierska, Jan Konopacki,
ABSTRACT Kowalczyk et al. (Hippocampus 2014; 24:7‐20) were probably the first to conduct a systemic study of posterior hypothalamic area (PHa) theta rhythm in anesthetized rats. They demonstrated that local PHa theta field potentials were tail‐pinch resistant and could be generated in urethane‐anesthetized rats independently of ongoing hippocampal formation theta rhythm. These in vivo data were also confirmed in PHa slice preparations perfused with cholinergic agonist, carbachol. In the current experiments ...
Tópico(s): Sleep and Wakefulness Research
2016 - Wiley | Hippocampus
Karolina Richter, Tomasz Stefura, Nikola Kłos, Jonasz Tempski, Marta Kołodziej-Rzepa, Michał Kisielewski, Tomasz Wojewoda, Wojciech M. Wysocki,
To date, there have been multiple studies and clinical guidelines or recommendations for complex management of melanoma patients. The most controversial subjects included the frequency of follow-up. This study provides a coherent and comprehensive comparison of conventional vs. reduced-frequency follow-up strategies for early-stage melanoma patients. The value of our study consists in the precise analysis of a large collection of articles and the selection of the most valuable works in relation ...
Tópico(s): CAR-T cell therapy research
2023 - Multidisciplinary Digital Publishing Institute | Current Oncology
Research findings concerning benzene, toluene, ethylobenzene, meta-, para- and ortho-xylene as well as styrene (BTEXS) emission at public cemeteries during All Saints' Day are presented here. Tests were carried out at town-located cemeteries in Opole and Grodków (southern Poland) and, as a benchmark, at the centres of those same towns. The purpose of the study was to estimate BTEXS emissions caused by the candle burning and, equally important to examine, whether emissions generated by the tested sources ...
Tópico(s): Vehicle emissions and performance
2013 - Springer Science+Business Media | Bulletin of Environmental Contamination and Toxicology
Anton Pashkevich, Eduard Bairamov, Marcin Jacek Kłos, Tomasz E. Burghardt, Matúš Šucha,
A wearable eye tracker was utilised to study paths and observation of directional signs at main railway station in Katowice. For the purpose of identifying confusion points due to inadequate signage, the task of finding the railway station from a tram stop, finding train schedule, ticket office, and then platform was assigned to 16 young people who were either familiar or not familiar with the area. No meaningful differences were found between the two groups in terms of time to complete the task ...
Tópico(s): Impact of Light on Environment and Health
2021 - Springer International Publishing | Lecture notes in networks and systems
Ḃ. Turek, C. Wajler, Z. Kłos, Tomasz Szara,
Tópico(s): Veterinary Orthopedics and Neurology
2013 - Polish Society of Veterinary Sciences | Medycyna Weterynaryjna
Ḃ. Turek, C Wajler, Z. Klos, Tomasz Szara,
Tópico(s): Mechanical Engineering and Vibrations Research
2013 - Polish Society of Veterinary Sciences | Medycyna Weterynaryjna
Michał Kisielewski, Karolina Richter, Magdalena Pisarska, Michał Wysocki, Nikola Kłos, Tomasz Stefura, Tomasz Wojewoda, Wojciech M. Wysocki,
Wound infection after intestinal ostomy closure is a very common postoperative complication. An alternative to primary wound suturing by single sutures or purse string sutures (PSS) is applying incisional negative pressure wound therapy (iNPWT). The aim of the following systematic review and meta-analysis was to assess and compare clinical outcomes in patients after PSS and iNPWT use.
Tópico(s): Surgical site infection prevention
2024 - Mary Ann Liebert, Inc. | Advances in Wound Care
Wojciech Pluskiewicz, Piotr Adamczyk, Edward Franek, Piotr Leszczyński, Ewa Sewerynek, Hanna Wichrowska, Luiza Napiórkowska, Tomasz Kostyk, Michał Stuss, Wioletta Stępień-Kłos, Bogna Drozdzowska,
The diagnosis of osteoporosis centres on the assessment of bone mineral density (BMD). Osteoporosis is defined as a BMD 2·5 SD or more below the average value for premenopausal women (T score <−2·5 SD). Severe osteoporosis denotes osteoporosis in the presence of one or more fragility fractures. The same absolute value for BMD used in women can be used in men. The recommended site for diagnosis is the proximal femur with dual energy X-ray absorptiometry (DXA). Other sites and validated techniques, however, ...
Tópico(s): Hip and Femur Fractures
2009 - Elsevier BV | Bone
Paweł Wielgosz, Tomasz Hadaś, Anna Kłos, Jacek Paziewski,
This review paper presents research results on geodetic positioning and applications carried out in Poland, and related to the activities of the International Association of Geodesy (IAG) Commission 4 "Positioning and Applications" and its working groups.It also constitutes the chapter 4 of the national report of Poland for the International Union of Geodesy and Geodynamics (IUGG) covering the period of 2015-2018.The paper presents selected research, reviewed and summarized here, that were carried ...
Tópico(s): Indoor and Outdoor Localization Technologies
2023 - De Gruyter Open | Geodesy and Cartography
Renata Bocian, Bartosz Caban, Paulina Kłos‐Wojtczak, Jan Konopacki, Tomasz Kowalczyk,
Data obtained in in vitro experiments and urethane anaesthetized animals have revealed that the mechanisms responsible for the generation of hippocampal cholinergic theta rhythm are specifically affected by the administration of broad spectrum gap junctions (GJs) blocker - carbenoxolone (CBX). The aim of this study was to examine the effect of GJs modulation on the production of posterior hypothalamic theta. Specifically, we were interested in evaluating whether CBX could attenuate the theta rhythm ...
Tópico(s): Memory and Neural Mechanisms
2016 - Wiley | European Journal of Neuroscience
Winfried Decking, Suren Abeghyan, P. Abramian, A. Abramsky, Aaron D. Aguirre, Clemens Albrecht, P. Alou, M. Altarelli, P. Altmann, K. Amyan, V.V. Anashin, Evstati Apostolov, Karen Appel, D. Auguste, V. Ayvazyan, Stefan Baark, F. Babies, N. Baboi, P. A. Bak, V. Balandin, R. Baldinger, B. Baranasic, S. Barbanotti, Oleg Belikov, V. A. Belokurov, L. Belova, V. A. Belyakov, S. D. Berry, Michele Bertucci, Bolko Beutner, Andreas Block, M. Blöcher, T. Böckmann, C. Bohm, M. Böhnert, V. T. Bondar', E. N. Bondarchuk, M. Bonezzi, Pawel Borowiec, Coleen S. Bosch, Ulrike Bösenberg, A. Bosotti, Ralph Bospflug, Michael Bousonville, E. Boyd, Y. Bozhko, A. Brand, Julien Branlard, S. Briechle, Frank Brinker, Sascha Brinker, R. Brinkmann, Sándor Brockhauser, Oleg Brovko, H. Brück, A. Brüdgam, Łukasz Butkowski, T. Büttner, J. Calero, E. Castro-Carballo, G. Cattalanotto, Joël Charrier, Jianliang Chen, A. Cherepenko, V. G. Cheskidov, Marco Chiodini, Andy Chong, S. Choroba, M. Chorowski, D V Churanov, W. Cichalewski, M. Clausen, William Andrew Clement, Christelle Cloué, J.A. Cobos, N. Coppola, S. Cunis, Krzysztof Czuba, Marie Kristin Czwalinna, B. Dalmagne, J. A. Dammann, H. Danared, Albrecht Wagner, A. Delfs, Thomas Delfs, Florian Dietrich, Tom Dietrich, M. Dohlus, M. Dommach, A. Donat, Xiaohao Dong, N. Doynikov, M. Dressel, M. Duda, P. Duda, Hans-Jörg Eckoldt, Wajid Ehsan, J. Eidam, F. Eints, Claudia Engling, U. Englisch, A. Ermakov, K. Escherich, J. Eschke, Evgeni Saldin, M. Faesing, A. Fallou, M. Felber, Michael Fenner, Bruno Fernandes, José Manuel Fernández Fernández, S. Feuker, K. Filippakopoulos, K. Floettmann, V.F. Fogel, M. Fontaine, Airán Francés, Idoia Freijo Martìn, Wolfgang Freund, T. Freyermuth, Michael Friedland, Lars Fröhlich, M. Fusetti, J. Fydrych, A. Gallas, O. García, L. García‐Tabarés, Gianluca Geloni, Natalia Gerasimova, Ch. Gerth, Patrick Geßler, V. Gharibyan, M. Gloor, J. Głowinkowski, A. Goessel, Z. Gołębiewski, N. Golubeva, W. Grabowski, W. Graeff, Alexander Grebentsov, M. Grecki, T. Grevsmuehl, Matthias Groß, Uwe Grosse‐Wortmann, Jan Grünert, S. Grunewald, P. Grzegory, Feng Gao, H. Guler, G. Gusev, J. L. Gutierrez, L. Hagge, M. Hamberg, R. Hanneken, E. Harms, Ingmar Hartl, A. Hauberg, Steffen Hauf, J. Hauschildt, Jens Hauser, Jan Havlíček, Anders Hedqvist, Niels Heidbrook, F. Hellberg, Denis Henning, O. Hensler, Tobias Hermann, A. Hidvégi, M. Hierholzer, Heiko Hintz, Frank Hoffmann, Markus Hoffmann, Matthias Hoffmann, Y. Holler, M. Hüning, Alexandr Ignatenko, Markus Ilchen, A. Iluk, J. Iversen, J. Iversen, Manuel Izquierdo, L. Jachmann, N. Jardon, U. Jastrow, Kay Jensch, J. Jensen, M. Jeżabek, M. Jidda, Hyunchang Jin, Niklas Johansson, R. Jonas, W. Kaabi, Daniela Kaefer, R. Kammering, H. Kapitza, Suren Karabekyan, S. Karstensen, Karol Kasprzak, V. Katalev, D. Keese, B. Keil, M.A. Kholopov, M. Killenberger, B. Kitaev, Y. Klimchenko, Ronald Klos, Lennart Knebel, Andreas Koch, M. E. Koepke, Sebastian Köhler, W. Köhler, N. Kohlstrunk, Zuzana Konôpková, Andrey O. Konstantinov, W. Kook, W. Koprek, M. Körfer, Olaf Korth, А. А. Kosarev, Konrad Kosiński, D. Kostin, Yauhen Kot, A. Kotarba, Tomasz Kozak, V. R. Kozak, R. Kramert, M. Krasilnikov, Alexander Krasnov, B. Krause, L. Kravchuk, Olaf Krebs, R. Kretschmer, Jens Kreutzkamp, O. Kröplin, Krzysztof Krzysik, G. Kube, H. Kuehn, Naresh Kujala, V. Kulikov, V. Kuzminych, Daniele La Civita, M. Lacroix, Thorsten Lamb, A. Lancetov, Mats Larsson, David Le Pinvidic, S. Lederer, Timmy-Jan Lensch, Dan Lenz, A. Leuschner, F. Levenhagen, Yuelin Li, J. Liebing, L. Lilje, T. Limberg, D. Lipka, B. List, J. Liu, S. Liu, B. Lorbeer, J. Lorkiewicz, Huihua Lu, Frank Ludwig, Karsten Machau, W. Maciocha, Catherine Madec, C. Magueur, C. Maiano, Irina L. Maksimova, K. Malcher, Theophilos Maltezopoulos, E.V. Mamoshkina, Bastian Manschwetus, F. Marcellini, Goran Marinković, T. Martı́nez, H. Martirosyan, W. Maschmann, M.A. Maslov, A. Matheisen, Uroš Mavrič, J. Meißner, K. W. Meißner, M. Messerschmidt, N. Meyners, G. Michalski, P. Michelato, N. Mildner, M. K. Moe, Francesca Moglia, Christian Mohr, S. Mohr, W.-D. Möller, M. Mommerz, Laura Monaco, C. Montiel,
The European XFEL is a hard X-ray free-electron laser (FEL) based on a high-electron-energy superconducting linear accelerator. The superconducting technology allows for the acceleration of many electron bunches within one radio-frequency pulse of the accelerating voltage and, in turn, for the generation of a large number of hard X-ray pulses. We report on the performance of the European XFEL accelerator with up to 5,000 electron bunches per second and demonstrating a full energy of 17.5 GeV. Feedback ...
Nature Portfolio
Maciej Rutkowski, Tomasz Matuszewski, Józef Kędziora, Marek Paradowski, Kajetan Klos, A. Zakrzewski,
It has been found during last years that vitamins A, C, E and carotenoids, besides previously recognized functions of preventing particular lipido- and avitaminosis, significantly participate in the protection of the human body against oxidation stress that is characterized by balance disturbance between speed of free radical creation and reactive oxygen forms with pace of their neutralization by enzymes and antioxidants. The antioxidative system creates special protective barrier which includes ...
Tópico(s): Vitamin C and Antioxidants Research
2010 - MedPress | Polski Merkuriusz Lekarski
Vasyl Martsenyuk, Георги Димитров, Dejan Rančić, Iveta Dirgová Ľuptáková, Igor Jovančević, Marcin Bernaś, Aleksandra Kłos-Witkowska, Tomasz Gancarczyk, Iva Kostadinova, Elizabet Mihaylova, Dragan Stojanović, Marko Milojković, Jiřı́ Pospı́chal, Aleksandar Plamenac,
The consortium of “The Future is in Applied Artificial Intelligence” Project designed the first competency-based applied artificial intelligence curriculum at the higher-education institution level. The development was based on advanced system research on existing artificial intelligence-related resources and surveying target groups of teachers, information technology students, and employers, which should enhance the performance of implementing artificial intelligence education. A review of applied ...
Tópico(s): Online Learning and Analytics
2024 - Multidisciplinary Digital Publishing Institute | Applied Sciences
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Tópico(s): Child Nutrition and Feeding Issues
2024 - Elsevier BV | Clinical Nutrition ESPEN