Shinsuke Koike, Saori Tanaka, Tomohisa Okada, Toshihiko Aso, Ayumu Yamashita, Okito Yamashita, Michiko Asano, Norihide Maikusa, Kentaro Morita, Naohiro Okada, Masaki Fukunaga, Akiko Uematsu, Hiroki Togo, Atsushi Miyazaki, Katsutoshi Murata, Yuta Urushibata, Joonas A. Autio, Takayuki Ose, Junichiro Yoshimoto, Toshiyuki Araki, Matthew F. Glasser, David C. Van Essen, Megumi Maruyama, Norihiro Sadato, Mitsuo Kawato, Kiyoto Kasai, Yasumasa Okamoto, Takashi Hanakawa, Takuya Hayashi,
Psychiatric and neurological disorders are afflictions of the brain that can affect individuals throughout their lifespan. Many brain magnetic resonance imaging (MRI) studies have been conducted; however, imaging-based biomarkers are not yet well established for diagnostic and therapeutic use. This article describes an outline of the planned study, the Brain/MINDS Beyond human brain MRI project (BMB-HBM, FY2018 ~ FY2023), which aims to establish clinically-relevant imaging biomarkers with multi-site ...
Tópico(s): Functional Brain Connectivity Studies
2021 - Elsevier BV | NeuroImage Clinical
Sei Nishida, Toshihiko Aso, Shigetoshi Takaya, Yuki Takahashi, Takayuki Kikuchi, Takeshi Funaki, Kazumichi Yoshida, Tomohisa Okada, Takeharu Kunieda, Kaori Togashi, Hidenao Fukuyama, Susumu Miyamoto,
The development of noninvasive approaches for identifying hypoperfused brain tissue at risk is of major interest. Recently, the temporal-shift (TS) maps estimated from resting-state blood oxygenation level-dependent (BOLD) signals have been proposed for determining hemodynamic state.To examine the equivalency of the TS map and the cerebrovascular reactivity (CVR) map derived from acetazolamide-challenged single-photon emission computed tomography (SPECT) in identifying hemodynamic impairment in patients ...
Tópico(s): Functional Brain Connectivity Studies
2018 - Lippincott Williams & Wilkins | Neurosurgery
Tomohisa Kunii, Toshie Iijima, Teruo Jojima, Masanori Shimizu, Masato Kase, Shintaro Sakurai, Takahiko Kogai, Isao Usui, Yoshimasa Aso,
Adefovir dipivoxil is a nucleotide analogue that is approved for treatment of chronic hepatitis B. Adefovir dipivoxil is associated with proximal tubular dysfunction, resulting in Fanconi syndrome, which can cause secondary hypophosphatemic osteomalacia. We describe a case of a patient with hypophosphatemic osteomalacia secondary to Fanconi syndrome induced by adefovir dipivoxil concomitantly with osteoporosis in whom clinical symptoms were improved by adding denosumab (a human monoclonal antibody ...
Tópico(s): Pharmacological Effects and Toxicity Studies
2019 - BioMed Central | Journal of Medical Case Reports
Shimpei Yamasaki, Toshihiko Aso, Jun Miyata, Genichi Sugihara, Masaaki Hazama, Kiyotaka Nemoto, Yujiro Yoshihara, Yukiko Matsumoto, Tomohisa Okada, Kaori Togashi, Toshiya Murai, Hidehiko Takahashi, Taro Suwa,
Abstract Recent studies examining electroconvulsive therapy (ECT) have reported that early sessions can induce rapid antidepressant and antipsychotic effects, and the early termination of ECT was reported to increase the risk of relapse. We hypothesized that different neural mechanisms associated with the therapeutic effects of ECT may be involved in the different responses observed during the early and late periods of ECT treatment. We investigated whether these antidepressant and antipsychotic ...
Tópico(s): Treatment of Major Depression
2020 - Springer Nature | Translational Psychiatry
Yuki Oi, Masakazu Hirose, Hiroki Togo, Kenji Yoshinaga, Thai Akasaka, Tomohisa Okada, Toshihiko Aso, Ryōsuke Takahashi, Matthew F. Glasser, Takuya Hayashi, Takashi Hanakawa,
The Human Connectome Project (HCP)-style surface-based brain MRI analysis is a powerful technique that allows precise mapping of the cerebral cortex. However, the strength of its surface-based analysis has not yet been tested in the older population that often presents with white matter hyperintensities (WMHs) on T2-weighted (T2w) MRI (hypointensities on T1w MRI). We investigated T1-weighted (T1w) and T2w structural MRI in 43 healthy middle-aged to old participants. Juxtacortical WMHs were often misclassified ...
Tópico(s): Advanced MRI Techniques and Applications
2023 - Elsevier BV | NeuroImage
Tomoyoshi Tamura, Ryo Yamamoto, Koichiro Homma, Nobuya Kitamura, Tomohisa Nomura, Takashi Tagami, Hideo Yasunaga, Shotaro Aso, Munekazu Takeda, Junichi Sasaki,
Background: Hyperuricemia is frequently seen in patients after cardiac arrest. Persistent hyperuricemia during a cellular energy crisis is believed to result from the breakdown of nucleotides into uric acid (UA) and indicates an insufficient restoration of adenosine triphosphate (ATP) synthesis. Hypothesis: Early reduction in serum UA level, UA clearance (UA-CL), is associated with survival after cardiac arrest. Aims: The study examined the association between UA-CL and 30-day survival following out- ...
Tópico(s): Cardiac Arrest and Resuscitation
2024 - Lippincott Williams & Wilkins | Circulation
Yuki Kishihara, Masahiro Kashiura, Hideto Yasuda, Nobuya Kitamura, Tomohisa Nomura, Takashi Tagami, Hideo Yasunaga, Shotaro Aso, Munekazu Takeda, Takashi Moriya,
Out-of-hospital cardiac arrest (OHCA) is a serious condition. The volume-outcome relationship and various post–cardiac arrest care elements are believed to be associated with improved neurological outcomes. Although previous studies have investigated the volume–outcome relationship, adjusting for post-cardiac arrest care, intra-class correlation for each institution, and other covariates may have been insufficient. To investigate the volume-outcome relationships and favorable neurological outcomes ...
Tópico(s): Trauma and Emergency Care Studies
2023 - Elsevier BV | The American Journal of Emergency Medicine
Boo‐Keun Khim, Ken Ikehara, Tomohisa Irino,
... through correlation of lightness ( L *) values and tephra (Aso‐4 and Toya) layers with those in the ...
Tópico(s): Isotope Analysis in Ecology
2011 - Wiley | Journal of Quaternary Science
Tomohisa TAKADA, Fumiya YAMANO, Yuki Akaike, Yoshitaka Sato, Masaru Fujita, Hayato Aso, Shinichi Nishida,
The purpose of this study is to produce the Cu-Ni-Si copper alloy strip by using a vertical type twin-roll casting process. The demand of Cu-Ni-Si copper alloy sheet called Corson alloy sheet has been increasing for small electronic devices because of these remarkable properties such as good bending workability, high strength and high conductivity. However it has difficulty for Cu-Ni-Si copper alloy to produce a thin strip by conventional hot rolling process, thus it needs many process because it ...
Tópico(s): Metallurgy and Material Forming
2015 - Japan Society Mechanical Engineers | The Proceedings of Ibaraki District Conference
Tomohisa Kunii, Isao Usui, Teruo Jojima, Masanori Shimizu, Masato Kase, Shintaro Sakurai, Takuya Tomaru, Toshie Iijima, Yoshimasa Aso,
Tópico(s): Diabetes Treatment and Management
2024 - Springer Science+Business Media | Diabetology International
Satoru Matsuda, Hiroya Takeuchi, Hirofumi Kawakubo, Ryo Takemura, Yusuke Maeda, Yuki Hirata, Takuji Kaburagi, Tomohisa Egawa, Tomohiko Nishi, Masaharu Ogura, Taku Miyasho, Akihiko Okamura, Shuhei Mayanagi, Kazumasa Fukuda, Rieko Nakamura, Tomoyuki Irino, Norihito Wada, Yuko Kitagawa,
Tópico(s): Pancreatic and Hepatic Oncology Research
2020 - Springer Science+Business Media | Annals of Surgical Oncology
... Suzuki Lee L. Swanstrom Minoru Tada Tadayuki Takagi Tomohisa Takagi Naminatsu Takahara Hiroyuki Takamaru Yuichi Takano Madoka ...
Tópico(s): Colorectal Cancer Screening and Detection
2020 - Wiley | Digestive Endoscopy