Toshiyuki Yano, Ryo Takahashi, Tomohisa Yamashita, Nobutaka Nagano, Aki Ishikawa, Akihiro Sakurai, Hiroki Maruyama, Tetsuji Miura,
... Sediment Toshiyuki Yano, MD, PhD, Ryo Takahashi, MD, Tomohisa Yamashita, MD, PhD, Nobutaka Nagano, MD, Aki Ishikawa, MD, ... of Medical and Dental Sciences, Japan (H.M.). , Tomohisa YamashitaTomohisa Yamashita From the Department of Cardiovascular, Renal and Metabolic ...
Tópico(s): Trypanosoma species research and implications
2017 - Lippincott Williams & Wilkins | Circulation Heart Failure
Shunji Nomura, Tomohisa Yamashita, Hisashi Yoshino, Ken Ando,
X‐ray lattice parameter measurements of the Bi 2‐ x (Sr,Ca) 3‐ y Cu 2‐ z O 8+ d system show that a continuously varying solid‐solution cation nonstoichiometry exists within the overall composition ranges x < 0.32, ‐0.2 < y < 0.32, and z < 0.25. A modulated structure along the b axis remains present over these composition ranges. Defects introduced by cation deficiency have been clarified to be vacancies by density measurements. The oxygen content determined by titration decreases proportionately with increasing ...
Tópico(s): Magnetic and transport properties of perovskites and related materials
1991 - Wiley | Journal of the American Ceramic Society
Tomohisa Yamashita, Tatsuya Uchida, Takanori Fukushima, Norio Teramae,
Solvent relaxation processes of 12-(9-anthroyloxy) stearic acid (12-AS) and 4-(9-anthroyloxy) butanoic acid (4-ABA) at the heptane/water interface are examined by time-resolved total internal reflection fluorescence spectroscopy. In a bulk heptane solution containing 3 M ethanol, both 12-AS and 4-ABA show time-dependent fluorescence spectral shifts, and the decay profiles can be analyzed by the two-state kinetics model. The results obtained for the binary mixture of heptane and ethanol can be ascribed ...
Tópico(s): Protein Interaction Studies and Fluorescence Analysis
2003 - American Chemical Society | The Journal of Physical Chemistry B
Marenao Tanaka, Hideaki Yoshida, Masato Furuhashi, Nobuhiko Togashi, Masayuki Koyama, Satoshi Yamamoto, Tomohisa Yamashita, Yusuke Okazaki, Shutaro Ishimura, Hideki Ota, Tadashi Hasegawa, Tetsuji Miura,
We examined the hypothesis that renal congestion is responsible for the decline in renal function in patients with heart failure (HF) via tubulointerstitial inflammation.First, in a longitudinal study, we retrospectively examined the relationship between cardiac functions and the decline of renal function during a period of 6.4±3.2 years in 20 patients who had a left ventricular ejection fraction of <40% and an estimated glomerular filtration ratio (eGFR) of <60 mL/min/1.73 m(2). Second, we compared ...
Tópico(s): Gout, Hyperuricemia, Uric Acid
2011 - The Japanese Society of Internal Medicine | Internal Medicine
A. Yamaguchi, Yosuke Amino, Kentaro Shima, Shintaro Suzuki, Tomohisa Yamashita, Norio Teramae,
The local environments surrounding dye molecules were studied with use of coumarin dyes in a mesostructured silica−surfactant nanocomposite, which was formed in a porous alumina membrane by a surfactant-templated method and has an average pore diameter of 3.4 nm. Coumarin dyes, such as coumarin 480 (C480), coumarin 343 (C343), and propylamide coumarin 343 (PAC343), were extracted into the silica−surfactant nanocomposite and time-resolved fluorescence spectra of these dyes were examined. C480 and C343 ...
Tópico(s): Mesoporous Materials and Catalysis
2006 - American Chemical Society | The Journal of Physical Chemistry B
Shuji Kodama, Sen‐ichi Aizawa, Atsushi Taga, Tomohisa Yamashita, Atsushi Yamamoto,
Abstract Six reducing monosaccharides (mannose, galactose, fucose, glucose, xylose, and arabinose) were derivatized with 1‐phenyl‐3‐methyl‐5‐pyrazolone (PMP) and chiral resolution of these racemic PMP‐monosaccharides was studied by ligand‐exchange CE using borate anion as a central ion of the chiral selector and ( S )‐3‐amino‐1,2‐propanediol (SAP) as a chiral selector ligand. PMP‐mannose, PMP‐galactose and PMP‐fucose were successfully enantioseparated. Lowering the capillary temperature increased the resolution ...
Tópico(s): Mass Spectrometry Techniques and Applications
2006 - Wiley | Electrophoresis
A. Yamaguchi, Masaki Nakano, Kimihisa Nochi, Tomohisa Yamashita, K. Morita, Norio Teramae,
Tópico(s): Advanced Fluorescence Microscopy Techniques
2006 - Springer Science+Business Media | Analytical and Bioanalytical Chemistry
Tomohisa Yamashita, Shuji Kodama, Mikiya Ohto, Eriko Nakayama, Sumiyo Hasegawa, Nobutaka Takayanagi, Tomoko Kemmei, A. Yamaguchi, Norio Teramae, Yukio Saitō,
The permeation fluxes of phenol, benzene sulfonate (BS) and benzene disulfonate (BDS) through a porous anodic alumina membrane with the perpendicularly oriented silica-surfactant nanochannel assembly membrane (NAM) were measured in water-ethanol mixture media. The permeation flux depended on solute charges and on solvent composition. As the ethanol ratio increased, the fluxes of BS and BDS increased and the flux of phenol decreased. The results of extraction/elution experiments also depended on the ...
Tópico(s): Analytical Chemistry and Sensors
2006 - Springer Nature | Analytical Sciences
Hideki Ota, Masato Furuhashi, Shutaro Ishimura, Masayuki Koyama, Yusuke Okazaki, Tomohiro Mita, Takahiro Fuseya, Tomohisa Yamashita, Marenao Tanaka, Hideaki Yoshida, Kazuaki Shimamoto, Tetsuji Miura,
Fatty acid-binding protein 4 (FABP4/A-FABP/aP2), a lipid chaperone, is expressed in both adipocytes and macrophages. Recent studies have shown secretion of FABP4 from adipocytes and association of elevated serum FABP4 level with obesity, insulin resistance, and atherosclerosis. However, little is known about the role of FABP4 in essential hypertension. We first examined serum FABP4 concentrations in 18 normotensives (NT) and 30 nontreated essential hypertensives (EHT). The EHT were divided into 18 ...
Tópico(s): Metabolomics and Mass Spectrometry Studies
2012 - Oxford University Press | American Journal of Hypertension
Satoshi Nagoya, Masamichi Usui, Takuro Wada, Tomohisa Yamashita, S. Ishii,
We treated four patients with periacetabular malignant tumours by pelvic reconstruction with a free vascularised fibular graft after resection of the tumour. The mean follow-up period was 32 months (9 to 39). The diagnosis was chondrosarcoma in three patients and osteosarcoma in one. In two patients total resection of the hemipelvis was required and in the other two less, but still massive, resection was undertaken. All were treated with an immediate free vascularised fibular graft which included ...
Tópico(s): Management of metastatic bone disease
2000 - British Editorial Society of Bone & Joint Surgery | Journal of Bone and Joint Surgery - British Volume
Hiroshi Akasaka, Hideaki Yoshida, Hideki Takizawa, Nagisa Hanawa, Toshiyuki Tobisawa, Marenao Tanaka, Norihito Moniwa, Nobuhiko Togashi, Tomohisa Yamashita, Setsuko Kuroda, Nobuyuki Ura, Tetsuji Miura,
BackgroundThe impact of elevation of the serum uric acid level (SUA) on the natural history of glomerular filtration rate (GFR) remains controversial.
Tópico(s): Hepatitis C virus research
2014 - Oxford University Press | Nephrology Dialysis Transplantation
Tomohisa Yamashita, Hiroyasu Matsushima, Itsuki Noda,
In this paper, we apply an exhaustive analysis to large-scale pedestrian flow in evacuating against tsunami. The exhaustive analysis is a method for understanding the tendency of behavior of a social system based on massive simulation scenarios. With the pedestrian simulation environment, we verify evacuation plan from the point of view of the number of the evacuees and overlapping of evacuation routes. As a result of our exhaustive analysis with 17,496 scenarios, especially in the case with many ...
Tópico(s): Transportation Planning and Optimization
2014 - Elsevier BV | Transportation research procedia
Shunji Nomura, Tomohisa Yamashita, Hisashi Yoshino, Ken Ando,
A single crystal of Bi 2.2 (Sr, Ca) 3- d Cu 2 O x was grown by a self-flux method using a solution containing excess Bi 2 O 3 and CuO compared to the composition of Bi 2 (Sr, Ca) 3- d Cu 2 O x in the Bi-Sr-Ca-Cu-O system. The dimensions of the single crystal obtained were up to 7×5×1 mm 3 . The critical temperature of the single crystal was 84 K which was determined by both magnetization and electrical resistivity measurements. The ratio of resistivities in the c -plane and along the c -axis was found ...
Tópico(s): Surface and Thin Film Phenomena
1988 - Institute of Physics | Japanese Journal of Applied Physics
Shuji Kodama, Atsushi Morikawa, Kazuya Nakagomi, Atsushi Yamamoto, Atsushi Satô, Kentaro Suzuki, Tomohisa Yamashita, Tomoko Kemmei, Atsushi Taga,
Nicotine (NC) and its related compounds (cotinine (CN), nornicotine (NN), anatabine (AT) and anabasine (AB)) were simultaneously enantioseparated by CE using a capillary with amino groups and sulfated beta-CD as a chiral selector. The optimum running conditions were found to be 30 mM acetate buffer (pH 5.0) containing 8% sulfated beta-CD with an applied voltage of +15 kV at 30 degrees C using direct detection at 260 nm. Using a capillary coated with amino groups, the EOF migrates toward the positive pole. ...
Tópico(s): Nicotinic Acetylcholine Receptors Study
2009 - Wiley | Electrophoresis
Shuji Kodama, Yuji Ito, Atsushi Taga, Yoko Nomura, Atsushi Yamamoto, Satoshi Chinaka, Kentaro Suzuki, Tomohisa Yamashita, Tomoko Kemmei, Kazuichi Hayakawa,
Glyphosate is an herbicide used for many plants that can be toxic to humans in high doses. Current methods for measuring glyphosate are slow and expensive. Here we describe a fast and simple method for measuring glyphosate in tea beverages by capillary electrophoresis with on-line formation of copper(II)-glyphosate complex. The optimum running conditions were found to be 40 mM acetate buffer (pH 5.0) containing 5 mM CuSO4 with an effective voltage of +15 kV using a sulfonated capillary (FunCap-CE Type ...
Tópico(s): Weed Control and Herbicide Applications
2008 - Pharmaceutical Society of Japan | JOURNAL OF HEALTH SCIENCE
Shuji Kodama, Sen‐ichi Aizawa, Atsushi Taga, Tomohisa Yamashita, Tomoko Kemmei, Kentaro Suzuki, Yoshitaka Honda, Atsushi Yamamoto,
Enantioseparation of tartaric acid by ligand exchange CE with a Cu(II)-D-quinic acid system was studied. Racemic tartaric acid was enantioseparated by ligand exchange CE using BGEs containing relatively low Cu(II)-D-quinic acid molar ratios ranging from 1:1 to 1:3 and high molar ratios ranging from 1:8 to 1:12 but was not enantioseparated using BGEs with medium molar ratios ranging from 1:4 to 1:6. While the migration order of D-tartaric acid was prior to L-tartaric acid at the lower Cu(II)-D-quinic ...
Tópico(s): Chemical and Physical Properties in Aqueous Solutions
2010 - Wiley | Electrophoresis
Shuji Kodama, Atsushi Taga, Atsushi Yamamoto, Yuji Ito, Yoshitaka Honda, Kentaro Suzuki, Tomohisa Yamashita, Tomoko Kemmei, Sen‐ichi Aizawa,
Abstract The ratio of citric acid to D ‐isocitric acid can be used to distinguish authentic and adulterated fruit juices. To separate DL ‐isocitric acid enantiomers, we used ligand exchange CE. D ‐Quinic acid was used as a chiral selector ligand and Mn(II), Fe(III), Co(II), Ni(II), Cu(II), and Zn(II) ions were used as the central ions of the chiral selector in the BGE. DL ‐Isocitric acid was found to be enantioseparated with the above metal ions except for Mn(II) ion. The optimum running conditions ...
Tópico(s): Chemical and Physical Properties in Aqueous Solutions
2010 - Wiley | Electrophoresis
K. Kuwano, M. Igarashi, S. Kusada, Kaoru Nemoto, T. Okutomi, Satoshi Hirano, Takaya Tominaga, M. Terai, T. Kuriyama, Kenji Tasaki, Taizo Tosaka, K. Marukawa, S. Hanai, Tomohisa Yamashita, Y. Yanase, Hiroyuki Nakao, M. Yamaji,
An HTS magnet for a Superconducting Maglev, consisting of four persistent current HTS coils, was developed. The HTS coils are installed in a cryostat, and cooled to approximately 15 K by conduction cooling, using two sets of two-stage GM type pulse tube cryocoolers. The HTS magnet is operated in a persistent current mode at a rated magneto-motive force of 750 kA. The running tests were executed on the Yamanashi Maglev Test Line, with a top speed of 553 km/h achieved on December 2, 2005. The test ...
Tópico(s): Superconducting Materials and Applications
2007 - IEEE Council on Superconductivity | IEEE Transactions on Applied Superconductivity
Shuji Kodama, Sen‐ichi Aizawa, Atsushi Taga, Tomohisa Yamashita, Tomoko Kemmei, Atsushi Yamamoto, Kazuichi Hayakawa,
Six reducing monosaccharides (mannose, galactose, fucose, glucose, xylose, and arabinose) were derivatized with 8-aminonaphthalene-1,3,6-trisulfonate (ANTS). Based on the chiral ligand-exchange principle using borate as a central ion of the chiral selector and (S)-3-amino-1,2-propanediol (SAP) as a chiral selector ligand, all of the six ANTS-monosaccharides were simultaneously enantioseparated using absorbance at 245 nm for detection. The optimum conditions for both high resolution and moderately short ...
Tópico(s): Mass Spectrometry Techniques and Applications
2007 - Wiley | Electrophoresis
S. Kusada, M. Igarashi, Kaoru Nemoto, T. Okutomi, Satoshi Hirano, K. Kuwano, Takaya Tominaga, M. Terai, T. Kuriyama, Kenji Tasaki, Taizo Tosaka, K. Marukawa, S. Hanai, Tomohisa Yamashita, Y. Yanase, Hiroyuki Nakao, M. Yamaji,
This paper describes the outline of a development project for the HTS magnet for the superconducting Maglev, which commenced in 1999. A very small current decay rate of 0.44%/day was achieved in 2003, using a prototype HTS coil, and a second HTS magnet, consisting of four persistent current HTS coils, was produced in 2005 for vehicle running tests. The second HTS magnet was operated in a persistent current mode at a rated magneto-motive force of 750 kA, and a top speed of 553 km/h was attained on ...
Tópico(s): Magnetic confinement fusion research
2007 - IEEE Council on Superconductivity | IEEE Transactions on Applied Superconductivity
Tomohisa Yamashita, Mineko Fujimiya, Kanna Nagaishi, Koji Ataka, Marenao Tanaka, Hideaki Yoshida, Kazufumi Tsuchihashi, Kazuaki Shimamoto, Tetsuji Miura,
Although diabetic nephropathy (DN) is a major cause of end-stage renal disease, the mechanism of dysfunction has not yet been clarified. We previously reported that in diabetes proinsulin-producing bone marrow-derived cells (BMDCs) fuse with hepatocytes and neurons. Fusion cells are polyploidy and produce tumor necrosis factor (TNF)-α, ultimately causing diabetic complications. In this study, we assessed whether the same mechanism is involved in DN. We performed bone marrow transplantation from male ...
Tópico(s): Hematopoietic Stem Cell Transplantation
2011 - Wiley | The FASEB Journal
Makoto Toida, K Shimokawa, Hiroki Makita, Kazuki Kato, Akio Kobayashi, Yukihiro Kusunoki, D. Hatakeyama, H. Fujitsuka, Tomohisa Yamashita, Takayuki Shibata,
We present a retrospective study of 82 patients with intraoral minor salivary gland tumors which were diagnosed from 1979 to 2003 in Gifu University Hospital. The histological diagnoses were reevaluated according to the 1991 WHO classification. A total of 82 tumors, consisting of 55 benign and 27 malignant tumors, were found in 28 male and 54 female Japanese patients; the male-to-female ratio was 1:1.9. The mean age of the patients was 51.4+/-18.1 years. The tumors affected the palate (n = 64), the ...
Tópico(s): Oral and Maxillofacial Pathology
2005 - Elsevier BV | International Journal of Oral and Maxillofacial Surgery
A. Yamaguchi, Jun Watanabe, Moataz Mekawy, Rise Fujiwara, K. Morita, Tomohisa Yamashita, Yosuke Amino, Yong Chen, Logudurai Radhakrishnan, Norio Teramae,
Extraction mechanisms of charged organic dye molecules are examined for an assembly of silica-surfactant nanochannels with a channel diameter of 3.4 nm, which is formed inside the pores of an anodic alumina membrane by a surfactant-template method. Experimental results confirm that the extraction mechanism depends on the sign of a charge of the dye molecules. The extraction of the cationic rhodamine 6G is predominantly caused by an ion-pair extraction process, whereas an anion-exchange process is ...
Tópico(s): Analytical Chemistry and Chromatography
2005 - Elsevier BV | Analytica Chimica Acta
A. Yamaguchi, Fumiaki Uejo, Takashi Yoda, Tatsuya Uchida, Yoshihiko Tanamura, Tomohisa Yamashita, Norio Teramae,
Tópico(s): Nanopore and Nanochannel Transport Studies
2004 - Nature Portfolio | Nature Materials
Tomohisa Yamashita, T. Okada, Itsuki Noda,
AbstractThis paper describes implementation of a pedestrian simulation environment to carry out an exhaustive analysis of huge-scale pedestrian flow. Our environment consists of the CrowdWalk pedestrian simulator and the PRACTIS simulation controller. CrowdWalk has three pedestrian movement models that are based on a one-dimensional space model. PRACTIS carries out an exhaustive and efficient analysis in a cluster environment to support effective decision-making, enabling pedestrians to be guided ...
Tópico(s): Traffic Prediction and Management Techniques
2013 - Taylor & Francis | SICE Journal of Control Measurement and System Integration
Yoshiki MIYAZAKI, Katsutoshi MIZUNO, Tomohisa Yamashita, Masafumi Ogata, Hitoshi Hasegawa, K. Nagashima, Shinichi Mukoyama, Taro Matsuoka, Kengo Nakao, Shinichi Horiuch, Tadakazu Maeda, Hideki Shimizu,
We have been developing a superconducting magnetic bearing (SMB) that has high temperature superconducting (HTS) coils and bulks for a flywheel energy storage system (FESS) that have an output capability of 300 kW and a storage capacity of 100 kW h (Nagashima et al., 2008, Hasegawa et al., 2015) [1,2]. The world largest-class FESS with a SMB has been completed and test operation has started. A CFRP flywheel rotor that had a diameter of 2 m and weight of 4000 kg had a capability to be rotated at a maximum ...
Tópico(s): Frequency Control in Power Systems
2016 - Elsevier BV | Cryogenics
Kouhei Ohno, Atsushi Kuno, Hiromichi Murase, Shingo Muratsubaki, Takayuki Miki, Masaya Tanno, Toshiyuki Yano, Satoko Ishikawa, Tomohisa Yamashita, Tetsuji Miura,
Acute kidney injury (AKI) after acute myocardial infarction (MI) worsens the prognosis of MI patients. Although type 2 diabetes mellitus (DM) is a major risk factor of AKI after MI, the underlying mechanism remains unclear. Here, we examined the roles of renal Toll-like receptors (TLRs) in the impact of DM on AKI after MI. MI was induced by coronary artery ligation in Otsuka-Long-Evans-Tokushima fatty (OLETF) rats, a rat DM model, and Long-Evans-Tokushima-Otsuka (LETO) rats, nondiabetic controls. Sham- ...
Tópico(s): Advanced Glycation End Products research
2017 - American Physical Society | AJP Heart and Circulatory Physiology
Shinichi Mukoyama, Kengo Nakao, H. Sakamoto, Taro Matsuoka, K. Nagashima, Masafumi Ogata, Tomohisa Yamashita, Yoshiki MIYAZAKI, Kazufumi Miyazaki, Tadakazu Maeda, Hideki Shimizu,
The world's largest-class flywheel energy storage system (FESS), with a 300 kW power, was established at Mt. Komekura in Yamanashi prefecture in 2015. The FESS, connected to a 1-MW megasolar plant, effectively stabilized the electrical output fluctuation of the photovoltaic (PV) power plant caused by the change in sunshine. The FESS uses a superconducting magnetic bearing (SMB) to levitate a heavy weight flywheel rotor without mechanical contact. The SMB consists of high-temperature superconducting ...
Tópico(s): Magnetic Bearings and Levitation Dynamics
2017 - IEEE Council on Superconductivity | IEEE Transactions on Applied Superconductivity
Carlos M. Ferrario, Jessica L. VonCannon, Sarfaraz Ahmad, Kendra N. Wright, Drew J. Roberts, Hao Wang, Tomohisa Yamashita, Leanne Groban, Che Ping Cheng, James F. Collawn, Louis J. Dell’Italia, Jasmina Varagić,
Angiotensin-(1-12) [Ang-(1-12)], an alternate substrate for tissue angiotensin II (Ang II) formation, underscores the importance of alternative renin-independent pathway(s) for the generation of angiotensins. Since renin enzymatic activity is species-specific, a transgenic model of hypertension due to insertion of the human angiotensinogen (AGT) gene in Sprague Dawley rats allowed for characterizing the contribution of a non-renin dependent mechanism for Ang II actions in their blood and heart tissue. ...
Tópico(s): Coagulation, Bradykinin, Polyphosphates, and Angioedema
2019 - Frontiers Media | Frontiers in Cardiovascular Medicine
Tomohisa Yamashita, Kazuyuki Yasukawa, Etsuko Yunoki,
Fluidic chip fabrication technologies using three-dimensional (3D) printing have received broad attention recently. Herein, we describe a new method for fabricating polydimethylsiloxane (PDMS) fluidic chips using a 3D-printed polyvinyl alcohol (PVA) or acrylonitrile butadiene styrene (ABS) template and polymer coating. In this method, polyethylene glycol (PEG) was coated on the 3D-printed template. This coated template was immersed in liquid PDMS, and subsequently the PDMS was cured. Space can be created ...
Tópico(s): 3D Printing in Biomedical Research
2019 - Springer Nature | Analytical Sciences