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Freedom Collection

Primary Document Acesso aberto

Whiston, James,

"Sold by Samuel Crouch, Edward Poole, and Joseph Fox ... "--p. 32 (2nd group) [Part 2] The mismanagements in trade discovered, has special t.-p. Book.

0000 - Gale Group | The Making of Modern World

Artigo Acesso aberto Revisado por pares

S Maneewannakul, Pushpa Kathir, Deanna Moore, Lindner Le, Jyh‐Horng Wu, K Ippen-Ihler,

... we have investigated the physical location of the traC and traW genes. We found that plasmid clones ... were able to complement transfer of F lac traC mutants and expressed an approximately 92,000-dalton product that comigrates with TraC. We also found that traW-complementing activity was ... The two different F DNA fragments that expressed traC and traW activities do not overlap. Our data indicate that the traC gene is located in a more-tra operon ... earlier maps and that traW is distal to traC. These results resolve a long-standing question concerning ...

Tópico(s): Bacterial Genetics and Biotechnology

1987 - American Society for Microbiology | Journal of Bacteriology

Artigo Acesso aberto Revisado por pares

Kimberly A. Schandel, Matthias M. Müller, Robert E. Webster,

TraC is one of the proteins encoded by the F transfer region of the F conjugative plasmid ... protein from the plasmid pKAS2, which carries only traC, resulted in the formation of inclusion bodies from which soluble TraC was purified. When small amounts of TraC were produced from pKAS2, the protein was localized to the cytoplasm by using anti-TraC antibodies. Similar analysis of a set of TraC-alkaline phosphatase fusion proteins localized all of these fusion proteins to the cytoplasm. However, when TraC was expressed from the F plasmid, much of ...

Tópico(s): Glycosylation and Glycoproteins Research

1992 - American Society for Microbiology | Journal of Bacteriology

Livro

National Bureau of Economic Research (NBER)

Artigo Acesso aberto Revisado por pares

Ana L.M. Giannini, Yifang Gao, Marie-José Bijlmakers,

... really interesting new gene) finger protein 125], or TRAC-1 (T-cell RING protein in activation 1), ... positive regulator of T-cell activation. In addition, TRAC-1 has been shown to down-modulate HIV ... terminal C3HC4 (Cys3-His-Cys4) RING domain, the TRAC-1 protein remains uncharacterized. In the present paper, we report novel interactions and modifications for TRAC-1, and elucidate its domain organization. Specifically, we determine that TRAC-1 associates with membranes and is excluded from ... a crucial role for the C-terminus in TRAC-1 function. In this region, novel domains were ...

Tópico(s): Immunotherapy and Immune Responses

2008 - Portland Press | Biochemical Journal

Primary Document Acesso aberto

Dymond, Jonathan,

"... to be held at [the Trac Association of Friends] depository, no. 84, Mulberry Street."--T.-p. The Trac Association of Friends was located at 84 Mulberry St. ...

0000 - Gale Group | SAS Part 1

Artigo Acesso aberto Revisado por pares

Dennis W. Wilson, Karen Oslund, Bonnie Lyons, Oded Foreman, Lisa Burzenski, Karen L. Svenson, Thomas H. Chase, Leonard D. Shultz,

... mice homozygous for the spontaneous thrombocytopenia and cardiomyopathy ( trac) mutation results from a single base pair change ... showed inflammation and myocyte degeneration in A/J- trac/trac mice beginning postweaning and progressed to marked dilative ... with normal myocytes suggesting myocyte repair. A/J- trac/trac mice fed lifelong phytosterol-free diets did not develop cardiomyopathy. BALB/cByJ- trac/trac mice had lesser inflammatory infiltrates and later onset DCM. BALB/cByJ- trac/trac mice changed from normal to phytosterol-free ...

Tópico(s): Atherosclerosis and Cardiovascular Diseases

2012 - SAGE Publishing | Toxicologic Pathology

Musical work Acesso aberto

... Miss Longman'. Printed music inserted: Emile Waldteufel: 'Tric trac polka'. For piano. Published by Hopwood & Crew, plate ...

0000 - Gale Group | NCCO British Theatre

Artigo Acesso aberto Revisado por pares

H. Zhao, Connie C. Li, Pardo Jorge, Peter C. Chu, Charlene Liao, Jianing Huang, John G. Dong, Xiulan Zhou, Qi Huang, Betty Huang, Mark K. Bennett, Susan M. Molineaux, Henry Lu, Sarkiz Daniel-Issakani, Donald G. Payan, Esteban S. Masuda,

TRAC-1 (T cell RING (really interesting new gene) protein identified in activation screen) is a novel ... surface activation marker screen. The C-terminal truncated TRAC-1 specifically inhibited anti-TCR-mediated CD69 up- ... cell line. In this study, we show that TRAC-1 is a RING finger ubiquitin E3 ligase ... of its amino-terminal RING finger domain abolished TRAC-1's ligase activity and the dominant inhibitory effect of C-terminal truncated TRAC-1 on TCR stimulation. The results of in vitro biochemical studies indicate that TRAC-1 can stimulate the formation of both K48- ...

Tópico(s): Immune Cell Function and Interaction

2005 - American Association of Immunologists | The Journal of Immunology

Musical work Acesso aberto

... Miss Longman'. Printed music inserted: Emile Waldteufel: 'Tric trac polka'. For piano. Published by Hopwood & Crew, plate ...

0000 - Gale Group | NCCO British Theatre

Artigo Acesso aberto Revisado por pares

Anthony N. Hollenberg, Tsuyoshi Monden, John P. Madura, Karen Lee, Fredric E. Wondisford,

Recently, a family of nuclear co-repressor proteins (TRACs) have been identified that interact with thyroid hormone ( ... report, we have cloned and characterized a human TRAC, which when expressed as a truncated protein lacking its repressing domains, can abolish endogenous cellular TRAC activity. Use of this inhibitor has uncovered a differential function of TRACs on negative versus positive thyroid hormone response elements ... of the TR A/B domain in modulating TRAC function. Thus, isoform-specific functions of the TR ...

Tópico(s): Estrogen and related hormone effects

1996 - Elsevier BV | Journal of Biological Chemistry

Musical work Acesso aberto

... Miss Longman'. Printed music inserted: Emile Waldteufel: 'Tric trac polka'. For piano. Published by Hopwood & Crew, plate ...

0000 - Gale Group | NCCO British Theatre

Carta Revisado por pares

Graeme J. Hankey,

... Young J et al.on behalf of the TRACS Trial CollaborationA structured training programme for caregivers of inpatients after stroke (TRACS): a cluster randomised controlled trial and cost-effectiveness ... the results of the training caregivers after stroke (TRACS) trial of the LSCTC in several stroke units ... Young J et al.on behalf of the TRACS Trial CollaborationA structured training programme for caregivers of inpatients after stroke (TRACS): a cluster randomised controlled trial and cost-effectiveness ...

Tópico(s): Acute Ischemic Stroke Management

2013 - Elsevier BV | The Lancet

Musical work Acesso aberto

... Miss Longman'. Printed music inserted: Emile Waldteufel: 'Tric trac polka'. For piano. Published by Hopwood & Crew, plate ...

0000 - Gale Group | NCCO British Theatre

Artigo Acesso aberto Revisado por pares

Amy Kind, Maria Brenny‐Fitzpatrick, Kris Leahy‐Gross, Jacquelyn Mirr, Elizabeth N. Chapman, Brooke Frey, Beth Houlahan,

... of Veterans Affairs ( VA ) Coordinated‐Transitional Care (C‐TraC) program is a low‐cost transitional care program ... community. The low‐cost, primarily telephone‐based C‐TraC program reduced 30‐day rehospitalizations by one‐third, ... VA hospitals have expressed interest in launching C‐TraC, but non‐ VA hospitals differ in important ways ... objective of this project was to adapt C‐TraC to the specific context of one non‐ VA ... Using this protocolized implementation approach, an adapted C‐TraC protocol was created and launched at the non‐ ...

Tópico(s): Interprofessional Education and Collaboration

2016 - Wiley | Journal of the American Geriatrics Society

Musical work Acesso aberto

... Miss Longman'. Printed music inserted: Emile Waldteufel: 'Tric trac polka'. For piano. Published by Hopwood & Crew, plate ...

0000 - Gale Group | NCCO British Theatre

Artigo Acesso aberto Revisado por pares

Heike Schmidt‐Eisenlohr, Natalie Domke, Christian Baron,

... biological experiments presented here show extracellular localization of TraC, as suggested by extracellular complementation of TraC-deficient bacteria by helper cells expressing a functional ... J. Bacteriol. 161:402–410, 1985). Overexpression of TraC and its export in large amounts into the ... extraction, ammonium sulfate precipitation, and column chromatography. Whereas TraC was soluble in overexpressing strains, it partly associated ... TraII region-encoded transfer machinery. Membrane association of TraC was reduced in strains carrying pKM101 derivatives with ...

Tópico(s): Bacteriophages and microbial interactions

1999 - American Society for Microbiology | Journal of Bacteriology

Musical work Acesso aberto

... Miss Longman'. Printed music inserted: Emile Waldteufel: 'Tric trac polka'. For piano. Published by Hopwood & Crew, plate ...

0000 - Gale Group | NCCO British Theatre

Revisão Acesso aberto Revisado por pares

Lawrence G. Lum,

... PBMC, whereas T cell receptor activated T cells (TRAC) are prepared by directly cross linking the T ... by expansion in low dose IL-2 (see TRAC). Anti-CD3 MAb Activation of T Cells ALT ... proliferation, cytokine synthesis, and immune responses.75-78 TRAC are produced by OKT3 and IL-2 (100 IU/ml) stimulation of PBMC (Fig. 4). TRAC have LAK- and NK-like cytotoxic properties and ... targeting antibodies or gene products. In preclinical models, TRAC exerted anti-tumor or antilymphoma effects. For example, TRAC reduced liver metastases due to MCA-38-LD ...

Tópico(s): Immune Cell Function and Interaction

1999 - Wiley | CA A Cancer Journal for Clinicians

Musical work Acesso aberto

... Miss Longman'. Printed music inserted: Emile Waldteufel: 'Tric trac polka'. For piano. Published by Hopwood & Crew, plate ...

0000 - Gale Group | NCCO British Theatre

Artigo Acesso aberto Revisado por pares

Raedun Clarke, Sjoukje van der Stegen, Chia‐Wei Chang, Mushtaq Husain, Yi-Shin Lai, Eigen Peralta, Laurel Stokely, Ramzey Abujarour, Jason Dinella, Tom Lee, Mochtar Pribadi, Helen Y. Chu, Chris Truong, Mohsen Sabouri-Ghomi, Miguel Meza, Judith Feucht, Justin Eyquem, Jorge Mansilla‐Soto, Isabelle Rivière, Michel Sadelain, Bahram Valamehr,

... CD19 CAR into the T cell receptor α (TRAC) locus to provide antigen specificity and enhanced efficacy ... contain the modified CD19 CAR targeted into the TRAC locus and hnCD16, and clonally selected to create a master hiPSC line (TRAC-TiPSC, FT819). Molecular characterization of the TRAC-TiPSC master cell line by 5' junction, 3' ... allelic targeting of the CD19 CAR into the TRAC locus. The origin of the clonal master cell ... T cell differentiation protocol, we demonstrate that the TRAC-TiPSCs yield TRAC-iT cells with uniform expression ...

Tópico(s): Nanowire Synthesis and Applications

2018 - Elsevier BV | Blood

Musical work Acesso aberto

... Miss Longman'. Printed music inserted: Emile Waldteufel: 'Tric trac polka'. For piano. Published by Hopwood & Crew, plate ...

0000 - Gale Group | NCCO British Theatre

Artigo Acesso aberto

Calvin N. Mooers,

A description of the TRAC (Text Reckoning And Compiling) language and processing algorithm is given. The TRAC language was developed as the basis of a software package for the reactive typewriter. In the TRAC language, one can write procedures for accepting, naming ... text; and for printing out any string. The TRAC language is based upon an extension and generalization ... concept of the “macro.” Through the ability of TRAC to accept and store definitions of procedures, the capabilities of the language can be indefinitely extended. TRAC can handle iterative and recursive procedures, and can ...

Tópico(s): Engineering and Information Technology

1966 - Association for Computing Machinery | Communications of the ACM

Musical work Acesso aberto

... Miss Longman'. Printed music inserted: Emile Waldteufel: 'Tric trac polka'. For piano. Published by Hopwood & Crew, plate ...

0000 - Gale Group | NCCO British Theatre

Artigo Acesso aberto Revisado por pares

Thomas H. Chase, Bonnie Lyons, Roderick T. Bronson, Oded Foreman, Leah Rae Donahue, Lisa Burzenski, Bruce Gott, PRISCILLA W. LANE, Belinda S. Harris, Uta Ceglarek, Joachim Thiery, Henning Wittenburg, Jonathan N. Thon, Joseph E. Italiano, Kenneth R. Johnson, Leonard D. Shultz,

Abstract The spontaneous mouse mutation “thrombocytopenia and cardiomyopathy” (trac) causes macrothrombocytopenia, prolonged bleeding times, anemia, leukopenia, infertility, ... functional impairments in activation and aggregation. Megakaryocytes in trac/trac mice are present in increased numbers, have poorly ... but is associated with a microenvironmental abnormality. The trac mutation maps to mouse chromosome 17, syntenic with ... complex that limits dietary phytosterol accumulation. Phytosterolemia in trac/trac mice confirmed a functional defect in the ...

Tópico(s): Platelet Disorders and Treatments

2009 - Elsevier BV | Blood