Yaser Bitar, Ulrike Holzgrabe,
... high resolution and short migration times of all tropa alkaloids were achieved by using heptakis(2,3-di-O-methyl-6-O-sulfo)-beta-CD and sulfated beta-CD in the microemulsion ...
Tópico(s): Innovative Microfluidic and Catalytic Techniques Innovation
2007 - Wiley | Electrophoresis
Maike Wedig, Ulrike Holzgrabe,
Anionic cyclodextrins (CDs), i.e., sulfated CD, sulfobutylether beta-CD (SBE-beta-CD) and heptakis(2,3-di-O-acetyl-6-sulfato)-beta-CD (HDAS-beta-CD), were used to separate the isomers of atropine, homatropine, ipratropium, scopolamine and butylscopolamine. Variations in the pH value and the concentration of the various CDs revealed the sulfated beta-CD to be superior to the other derivatives. In a basic medium at low concentrations of sulfated CD the enantiomers of atropine, homatropine and ipratropium ...
Tópico(s): Innovative Microfluidic and Catalytic Techniques Innovation
1999 - Wiley | Electrophoresis