By Fred Emery Political Editor, From David Bonavia, By Edward Townsend, By Our Political Editor, From Michael Leapman, From Craig Seton, By Donald Macintyre Labour Reporter, By Our Labour Staff, By Nicholas Timmins, By Pearce Wright Science Editor, By Ian Bradley, By Peter Evans Home Affairs Correspondent, By a Staff Reporter, By Michael Baily Transport Correspondent, From Tim Jones, By Lucy Hodges, By Our Motoring Correspondent, By David Nicholson-Lord, By Pat Healy Social Services Correspondent, By Our Agriculture Correspondent, From Ronald Faux, By Martin Huckerby, By George Clark Political Correspondent, From Charles Hargrove, From Gretel Spitzer, From Our Correspondent, From Richard Wigg, From Patricia Clough, From Tony Allaway, From Moshe Brilliant, From David Cross, From Christopher Wenner, From David Watts, By Caroline Moorehead, By Norman Fox Football Correspondent, By Rex Bellamy Squash Rackets Correspondent, By a Special Correspondent, By Peter Walker, By Iain Mackenzie, From John Woodcock Cricket Correspondent, By Paul Harrison, By Srikumar Sen Boxing Correspondent, By Joyce Whitehead, By Keith Macklin, By Michael Phillips Racing Correspondent, Brian Connell, Philip Howard, William Mann, Stanley Sadie, Paul Griffiths, Max Harrison, Joan Chissell, Michael Church, Joan Bakewell, John Percival, Richard Williams, Baron Phillips, Eric Heffer, Michael Leapman, George Hill, David Wood, GORDON MURSELL, , DAVID WESTON, , ANN DALLY, , R. P. W. WALL, , G. L. B. PITT, , TED KNIGHT, , PENELOPE ROPER, , PHILIP ROGERS, , W. H. PALMER, , WALSTON, , PAMELA BENTLEY, , DESMOND BURTON, , E. L. GILDER, , ELFRIDA MANNING, , By Clifford Longley, By Our Bridge Correspondent, By the Staff of Nature, From Our Special Correspondent, Hugh Clayton, By Geraldine Norman Sale Room Correspondent, A colleague writes:, By Peter Hill Industrial Editor, By Clifford Webb, By John Huxley, Frank Vogl, By John Huxley and Peter Norman, By Philip Robinson, By Our Industrial Staff, From Peter Norman, By Derek Harris, Iain Murray, Patricia Tisdall, E. IRA BROWN, , IAN FINDLAY, , ANDREW WINGFIELD, , BY THE FINANCIAL EDITOR, Peter Hill, Mario Modiano, Bryan Appleyard, Ronald Faux, Catherine Gunn, Michael Clark, Rosemary Unsworth, David Robinson, Michael Prest Commodities correspondent, Edited by Peter Dear,
... jailbreak fails, Prisoners of conscience São Tomé: Miguel Trovoada, Stories of maltreatment by the Iranians continue as ...
1981 - Gale Group | TDA
Antonio Salas, Ãngel Carracedo, Martin Richards, Vincent Macaulay,
... Google Scholar AngolaresSão Tomé and Príncipe30Trovoada et al. Trovoada et al., 2004Trovoada MJ Pereira L Gusmao L ... Google Scholar ForrosSão Tomé and Príncipe34Trovoada et al. Trovoada et al., 2004Trovoada MJ Pereira L Gusmao L ... Google Scholar TongasSão Tomé and Príncipe38Trovoada et al. Trovoada et al., 2004Trovoada MJ Pereira L Gusmao L ...
Tópico(s): Molecular Biology Techniques and Applications
2005 - Elsevier BV | The American Journal of Human Genetics
Erdembileg Anuurad, Masayuki Yamasaki, Neil S. Shachter, Thomas A. Pearson, Lars Berglund,
... Full Text PDF PubMed Google Scholar, 19Seixas S. Trovoada M.J. Rocha J. Haplotype analysis of the ... Africans from Sao Tome e Principe (19Seixas S. Trovoada M.J. Rocha J. Haplotype analysis of the ...
Tópico(s): Liver Disease Diagnosis and Treatment
2009 - Elsevier BV | Journal of Lipid Research
Maria Rosário Sambo, Maria Jesus Trovoada, Carla Benchimol, Vatúsia Quinhentos, Lígia Antunes Gonçalves, Rute Velosa, Isabel Marques, Nuno Sepúlveda, Taane G. Clark, Stefan Mustafa, Oswald Wagner, António Coutinho, Carlos Penha‐Gonçalves,
Background Cerebral malaria (CM) represents a severe outcome of the Plasmodium falciparum infection. Recent genetic studies have correlated human genes with severe malaria susceptibility, but there is little data on genetic variants that increase the risk of developing specific malaria clinical complications. Nevertheless, susceptibility to experimental CM in the mouse has been linked to host genes including Transforming Growth Factor Beta 2 (TGFB2) and Heme oxygenase-1 (HMOX1). Here, we tested whether ...
Tópico(s): Complement system in diseases
2010 - Public Library of Science | PLoS ONE
Maria Jesus Trovoada, Luı́sa Pereira, Leonor Gusmão, Augusto Abade, António Amorim, Maria João Prata,
Summary We have analysed the matrilineal genetic composition of three self‐reported ethnic groups from São Tomé e Príncipe (Gulf of Guinea), an African archipelago whose settlement begun in the late fifteenth century. Sequence data from the hypervariable segments I (HVS‐I) and II (HVS‐II) were obtained for 30 Angolares, 35 Forros and 38 Tongas. The repertory of mtDNA lineages in São Tomé e Príncipe denoted a fully African maternal pool, primarily arisen from a Central/Southwestern substratum. The absence ...
Tópico(s): Molecular Biology Techniques and Applications
2004 - Wiley | Annals of Human Genetics
Maria de Jesus Trovoada, Madalena Martins, Riadh Ben Mansour, Maria do Rosário Sambo, Ana B. Fernandes, Lígia Antunes Gonçalves, Artur Borja, Roni Moya, Paulo Almeida, João Costa, Isabel Marques, Maria Paula Macedo, António Coutinho, David L. Narum, Carlos Penha‐Gonçalves,
Nitric oxide (NO) is a proposed component of malaria pathogenesis, and the inducible nitric oxide synthase gene (NOS2) has been associated to malaria susceptibility. We analyzed the role of NOS2 polymorphisms on NO bioavailability and on susceptibility to infection, Plasmodium carrier status and clinical malaria. Two distinct West African sample collections were studied: a population-based collection of 1,168 apparently healthy individuals from the Príncipe Island and a hospital-based cohort of 269 ...
Tópico(s): Mosquito-borne diseases and control
2013 - American Society for Microbiology | Infection and Immunity
Elizabeth Ann Ball, Maria Rosário Sambo, Madalena Martins, Maria Jesus Trovoada, Carla Benchimol, João Costa, Lígia Antunes Gonçalves, António Coutinho, Carlos Penha‐Gonçalves,
Development of cerebral malaria (CM), a severe and fatal form of clinical Plasmodium falciparum infection, results from a damaging cascade of vascular, inflammatory, and immunological host responses that leads to brain injury. Progression to CM can be modified by host genetic factors. Our case-control study in Angolan children aimed at highlighting the role of IFN (α, β) receptor 1 (IFNAR1) in progression to CM. We report a robust association between IFNAR1 and CM protection, as well as detailed studies ...
Tópico(s): HIV Research and Treatment
2013 - American Association of Immunologists | The Journal of Immunology
Susana Seixas, Óscar García, Jesus Trovoada, Teresa Almeida‐Santos, António Amorim, Jorge Rocha,
Tópico(s): Blood Coagulation and Thrombosis Mechanisms
2001 - Springer Science+Business Media | Human Genetics
Marina Silva, Farida Alshamali, Paula Silva, Carla Carrilho, Flávio Mandlate, Maria Jesus Trovoada, Viktor Černý, Luı́sa Pereira, Pedro Soares,
Mitochondrial DNA (mtDNA) haplogroup L2 originated in Western Africa but is nowadays spread across the entire continent. L2 movements were previously postulated to be related to the Bantu expansion, but L2 expansions eastwards probably occurred much earlier. By reconstructing the phylogeny of L2 (44 new complete sequences) we provide insights on the complex net of within-African migrations in the last 60 thousand years (ka). Results show that lineages in Southern Africa cluster with Western/Central ...
Tópico(s): Pleistocene-Era Hominins and Archaeology
2015 - Nature Portfolio | Scientific Reports
Tsai‐Ying Yen, Maria de Jesus Trovoada dos Santos, Lien-Feng Tseng, Shu-Feng Chang, Chien-Fu Cheng, Arlindo Vicente de Assunção Carvalho, Pei‐Yun Shu, Jih-Ching Lien, Kun‐Hsien Tsai,
Dengue fever has become a worldwide public health concern, threatening an estimated 40% of the world's population. However, most resources and attention are still focused on malaria, while dengue statuses are poorly recognized in many African countries. In this serological survey, dengue virus (DENV) transmission was demonstrated by using serum samples collected from 78 pregnant women in the Democratic Republic of Sao Tome and Principe (DRSTP) during 2003 to 2004. Immunofluorescence assay was performed ...
Tópico(s): Malaria Research and Control
2015 - Elsevier BV | Acta Tropica
Carine Dochez, Rosemary J. Burnett, Symplice Mbola Mbassi, Fred Were, Andrew Munyalo Musyoki, Daisy Trovoada, M. Jeffrey Mphahlele,
Several African countries have recently introduced or are currently introducing the HPV vaccine, either nationwide or through demonstration projects, while some countries are planning for introduction. A collaborative project was developed to strengthen country adolescent immunisation programmes and health systems in the African Region, addressing unique public health considerations of HPV vaccination: adolescents as the primary target group, delivery platforms (e.g. school-based and facility based), ...
Tópico(s): Hepatitis B Virus Studies
2017 - Elsevier BV | Papillomavirus Research
David Albuquerque, Licínio Manco, Kovana Marcel Loua, Ana Paula Arez, Maria de Jesus Trovoada, Luís Relvas, Tamba S. Millimono, Silvia L. Rath, Dinora Lopes, Fátima Nogueira, Luís Varandas, Manuela Álvarez, Letícia Ribeiro,
Background: Ferroportin is a transmembrane protein responsible for iron export from enterocytes and macrophages. Mutation c.744G → T (Q248H), located in exon 6 of the ferroportin gene SLC40A1, is found as a polymorphism in populations of African origin. This mutation has been extensively analysed in African-Americans, but poorly studied in native African populations.Aim: To increase information about Q248H mutation frequency in native sub-Saharan populations examining three West African populations. ...
Tópico(s): RNA regulation and disease
2011 - Informa | Annals of Human Biology
Maria Jesus Trovoada, Cı́ntia Alves, Leonor Gusmão, Augusto Abade, António Amorim, Maria João Prata,
Seven Y‐chromosome STR loci, DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392 and DYS393 have been analysed in population samples of Angolares, Forros and Tongas, three ethnic groups from the African archipelago of São Tomé e Príncipe (Gulf of Guinea). Complete typings were obtained for 103 chromosomes, which belonged to 79 different haplotypes. The mean heterozygosity per locus in the overall São Tomean sample was 0.566, with the highest value found among Forros and the lowest among Angolares. Angolares ...
Tópico(s): Forensic and Genetic Research
2001 - Wiley | Annals of Human Genetics
Maria Jesus Trovoada, Lígia Tavares, Leonor Gusmão, Cı́ntia Alves, Augusto Abade, António Amorim, Maria João Prata,
Summary Twenty biallelic Y chromosome markers were analyzed in Angolares, Forros and Tongas, three population groups from the African archipelago of São Tomé e Príncipe. While most male lineages belonged to sub‐Saharan haplogroups, the component of European origin added up 23.9% in the archipelago. This contrasts with the reported absence of European mtDNA lineages, and the combined findings testify to a strong sex‐biased admixture process during the long‐lasting colonial period in São Tomé e Príncipe. ...
Tópico(s): Genetic diversity and population structure
2006 - Wiley | Annals of Human Genetics
Leonor Gusmão, Maria João Prata, Carlos J. Miranda, Maria de Jesus Trovoada, António Amorim,
Allele frequencies for eight STRs (CD4, FES/FPS, MBPB, TH01, TP53, TPO, F13A1, VWA) were estimated from samples (sized between 279 and 328) of unrelated individuals born in S. Tomé e Príncipe (Gulf of Guinea, West Africa).
Tópico(s): Forensic and Genetic Research
2001 - Elsevier BV | Forensic Science International
Maria João Prata, António Amorim, Leonor Gusmão, Maria Jesus Trovoada,
Tópico(s): Forensic and Genetic Research
1996 - Springer Nature | Advances in forensic haemogenetics
Produção Nacional
Matheus José Arruda Lyra, Osmar Evandro Toledo Bonfim, N. I. Fedorova, Vladimir Levit,
... a confecção dos campos meteorológicos. Os dados de trovoada foram obtidos através do satélite Tropical Rainfall Measuring ...
Tópico(s): Rural Development and Agriculture
2019 - UNIVERSIDADE FEDERAL DE PERNAMBUCO | Revista Brasileira de Geografia Física
Ana Raquel Matias, Paulo Feytor Pinto,
... the contextual and theoretical assumptions of the project ‘Trovoada de Ideias: Linguistic and social inclusion of students ...
Tópico(s): EFL/ESL Teaching and Learning
2020 - ISCTE – Lisbon University Institute | Portugese Journal of Social Sciences
Licínio Manco, Ana Oliveira, Catarina Gomes, Andre Granjo, Maria de Jesus Trovoada, Letícia Ribeiro, Augusto Abade, António Amorim,
Four intragenic PKLR polymorphisms [1705A/C, 1738C/T, T10/19, and (ATT)n microsatellite] were studied in normal population samples of Central Portugal and Sao Tome e Principe, a small archipelago located in the Gulf of Guinea, West Africa. For all loci, the observed genotype distributions do not deviate from Hardy-Weinberg equilibrium. The allele frequencies found in the Portuguese population are similar to those previously described in Caucasian populations. Mother-child pair analysis for the (ATT) ...
Tópico(s): RNA regulation and disease
2001 - Wayne State University Press | Human Biology
Susana Seixas, Maria Jesus Trovoada, M. Teresa Santos, Jorge Rocha,
Tópico(s): Virology and Viral Diseases
1999 - Wiley | Human Mutation
Produção Nacional
Matheus José Arruda Lyra, Lucas Barbosa Cavalcante, Vladimir Levit, N. I. Fedorova,
... identificados 16 casos de CCM, com registro de trovoada associada em 6 eventos. Quatro diferentes padrões sinóticos ...
Tópico(s): Environmental and biological studies
2017 - Escola Superior de Sustentabilidade | Revista Ibero-Americana de Ciências Ambientais
Paulo Sergio Faro Santos, Bruno Augusto Telles Vanessa Rizelio,
Tópico(s): Intracranial Aneurysms: Treatment and Complications
2018 - | Headache Medicine/Revista Headache Medicine
Susana Seixas, Maria Jesus Trovoada, M. Teresa Santos, Jorge Rocha,
... PortugalSearch for more papers by this authorM. Jesus Trovoada, M. Jesus Trovoada Departamento de Antropologia da Universidade de Coimbra, PortugalSearch ... PortugalSearch for more papers by this authorM. Jesus Trovoada, M. Jesus Trovoada Departamento de Antropologia da Universidade de Coimbra, PortugalSearch ...
Tópico(s): Peptidase Inhibition and Analysis
1999 - Wiley | Human Mutation
... Popular dissatisfaction is growing with Prime Minister Patrice Trovoada's authoritarian style and the government's failure ... claiming to have foiled an assassination attempt against Trovoada. Impacts Trovoada’s administration will try to mend damaged relations ...
Tópico(s): Legal Issues in South Africa
2018 - Emerald Publishing Limited | Emerald expert briefings
Significance Vila Nova justified his decision by citing Trovoada’s supposed inability to govern adequately. The move ... months of growing tensions between the two leaders. Trovoada has denounced his dismissal as unconstitutional. Impacts Harsh ...
Tópico(s): HIV/AIDS Impact and Responses
2025 - Emerald Publishing Limited | Emerald expert briefings
Edwans Silva Cordeiro, Nídia Maria da Silva, Vladimir Levit, N. I. Fedorova,
A previsão do fenômeno adverso trovoada tem extrema importância para segurança de toda população em Alagoas e especialmente para transporte aéreo. A elaboração do método de previsão ... feita para todos os 70 casos observados com trovoada no período de 2008-2012. A comparação da ...
Tópico(s): Geography and Environmental Studies
2013 - UNIVERSIDADE FEDERAL DE PERNAMBUCO | Revista Brasileira de Geografia Física
Maria Rosário Sambo, Carlos Penha‐Gonçalves, Maria Jesus Trovoada, João Costa, Roberto Lardoeyt Ferrer, António Coutinho,
Haemoglobin S (HbS) is the gene known to confer the strongest advantage against malaria morbidity and mortality. Multiple HbS effects have been described resulting in protection against parasitaemia and reduction of severe malaria risk. This study aimed to explore HbS protection against severe malaria and Plasmodium falciparum parasitaemia in Angolan children exhibiting different severe malaria syndromes. A case–control study was designed with 430 malaria cases (n = 288 severe malaria and n = 142 uncomplicated ...
Tópico(s): Iron Metabolism and Disorders
2015 - BioMed Central | Malaria Journal
Susana Seixas, M. Jesus Trovoada, M. Teresa Santos, Jorge Rocha,
Tópico(s): Virology and Viral Diseases
1999 - Wiley | Human Mutation
Luı́sa Pereira, Leonor Gusmão, Maria João Prata, Paulo Mota, Maria Jesus Trovoada, António Amorim,
Tópico(s): RNA and protein synthesis mechanisms
1999 - Springer Science+Business Media | International Journal of Legal Medicine